Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000137834 Gene ID 4091 Accession 6772
Symbol SMAD6 Alias AOVD2;MADH6;MADH7;HsT17432 Full Name SMAD family member 6
Status Confidence Length 80614 bases Strand Plus strand
Position 15 : 66702236 - 66782849 RNA binding domain N.A.
Summary The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36930678 PCB: A pseudotemporal causality-based Bayesian approach to identify EMT-associated regulatory relationships of AS events and RBPs during breast cancer progression. Liangjie Sun 2023-03-01 PLoS computational biology

Transcripts

Name Transcript ID bp Protein Translation ID
SMAD6-201 ENST00000288840 3828 496aa ENSP00000288840
SMAD6-205 ENST00000612349 5198 No protein -
SMAD6-202 ENST00000557916 1401 338aa ENSP00000452955
SMAD6-204 ENST00000559931 573 62aa ENSP00000453446
SMAD6-203 ENST00000558937 632 55aa ENSP00000452694

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
70558Body Mass Index9E-625673412
70559Waist-Hip Ratio9E-625673412
75130Body Mass Index1E-625673412
75131Waist-Hip Ratio1E-625673412
85338Body Mass Index1E-1025673412
85339Waist-Hip Ratio1E-1025673412
89885Body Mass Index3E-725673412
89886Waist-Hip Ratio3E-725673412
99224Subcutaneous Fat9E-622589738
100548Waist-Hip Ratio8E-925673412
104576Body Mass Index3E-1125673412
104577Waist-Hip Ratio3E-1125673412

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000137834homo_sapiensENSP0000036915437.259126.9807homo_sapiensENSP0000028884035.080625.4032
ENSG00000137834homo_sapiensENSP0000026216039.400428.0514homo_sapiensENSP0000028884037.096826.4113
ENSG00000137834homo_sapiensENSP0000033297343.058829.8824homo_sapiensENSP0000028884036.895225.6048
ENSG00000137834homo_sapiensENSP0000030576938.494626.8817homo_sapiensENSP0000028884036.088725.2016
ENSG00000137834homo_sapiensENSP0000044195437.634426.6667homo_sapiensENSP0000028884035.282325
ENSG00000137834homo_sapiensENSP0000034155133.152223.0072homo_sapiensENSP0000028884036.895225.6048
ENSG00000137834homo_sapiensENSP0000026215864.319352.3474homo_sapiensENSP0000028884055.241944.9597

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000137834homo_sapiensENSP0000028884089.516188.1048nomascus_leucogenysENSNLEP0000004895595.483993.9785
ENSG00000137834homo_sapiensENSP0000028884097.983997.7823pan_paniscusENSPPAP0000000899298.181897.9798
ENSG00000137834homo_sapiensENSP0000028884058.064552.4194pongo_abeliiENSPPYP0000003429347.213142.623
ENSG00000137834homo_sapiensENSP0000028884099.798499.7984pan_troglodytesENSPTRP0000001231899.798499.7984
ENSG00000137834homo_sapiensENSP0000028884087.701687.5gorilla_gorillaENSGGOP0000001267810099.7701
ENSG00000137834homo_sapiensENSP0000028884065.927460.0806ornithorhynchus_anatinusENSOANP0000004510674.657568.0365
ENSG00000137834homo_sapiensENSP0000028884084.475881.25sarcophilus_harrisiiENSSHAP0000000919783.967980.7615
ENSG00000137834homo_sapiensENSP0000028884084.87981.6532notamacropus_eugeniiENSMEUP0000000830484.368781.1623
ENSG00000137834homo_sapiensENSP0000028884096.975895.3629dasypus_novemcinctusENSDNOP0000000636596.586394.9799
ENSG00000137834homo_sapiensENSP0000028884053.225851.0081echinops_telfairiENSETEP0000000559290.102486.3481
ENSG00000137834homo_sapiensENSP0000028884097.983996.9758callithrix_jacchusENSCJAP0000005547397.786796.7807
ENSG00000137834homo_sapiensENSP0000028884099.596899.5968cercocebus_atysENSCATP0000000040399.596899.5968
ENSG00000137834homo_sapiensENSP0000028884099.596899.3952macaca_mulattaENSMMUP0000004437299.596899.3952
ENSG00000137834homo_sapiensENSP0000028884099.395299.3952macaca_nemestrinaENSMNEP0000002175599.395299.3952
ENSG00000137834homo_sapiensENSP0000028884099.596899.5968papio_anubisENSPANP0000004653099.596899.5968
ENSG00000137834homo_sapiensENSP0000028884081.048480.6452tursiops_truncatusENSTTRP0000000970581.707381.3008
ENSG00000137834homo_sapiensENSP0000028884062.298457.8629vulpes_vulpesENSVVUP0000001975670.387265.3759
ENSG00000137834homo_sapiensENSP0000028884094.556493.5484mus_spretusMGP_SPRETEiJ_P009190094.747593.7374
ENSG00000137834homo_sapiensENSP0000028884062.558.0645equus_asinusENSEASP0000503607653.173249.3997
ENSG00000137834homo_sapiensENSP0000028884096.774295.7661capra_hircusENSCHIP0000000996696.579595.5734
ENSG00000137834homo_sapiensENSP0000028884097.177495.7661loxodonta_africanaENSLAFP0000000808496.981995.5734
ENSG00000137834homo_sapiensENSP0000028884097.983997.7823panthera_leoENSPLOP0000001016497.590497.3896
ENSG00000137834homo_sapiensENSP0000028884097.37997.1774ailuropoda_melanoleucaENSAMEP0000003502997.773397.5708
ENSG00000137834homo_sapiensENSP0000028884096.774295.7661bos_indicus_hybridENSBIXP0000502782590.737289.7921
ENSG00000137834homo_sapiensENSP0000028884042.137141.7339oryctolagus_cuniculusENSOCUP000000053159594.0909
ENSG00000137834homo_sapiensENSP0000028884098.387198.1855equus_caballusENSECAP0000007767597.99297.7912
ENSG00000137834homo_sapiensENSP0000028884096.37195.5645canis_lupus_familiarisENSCAFP0084502294295.791694.99
ENSG00000137834homo_sapiensENSP0000028884097.782397.5806panthera_pardusENSPPRP0000000731697.782397.5806
ENSG00000137834homo_sapiensENSP0000028884088.508187.0968marmota_marmota_marmotaENSMMMP0000000674390.515589.0722
ENSG00000137834homo_sapiensENSP0000028884097.782397.379balaenoptera_musculusENSBMSP0001000535797.782397.379
ENSG00000137834homo_sapiensENSP0000028884093.951691.3306cavia_porcellusENSCPOP0000000138891.732389.1732
ENSG00000137834homo_sapiensENSP0000028884097.782397.5806felis_catusENSFCAP0000001141397.585597.3843
ENSG00000137834homo_sapiensENSP0000028884093.7592.3387ursus_americanusENSUAMP0000002656496.074494.6281
ENSG00000137834homo_sapiensENSP0000028884084.475881.8548monodelphis_domesticaENSMODP0000001201883.300280.7157
ENSG00000137834homo_sapiensENSP0000028884096.774295.7661bison_bison_bisonENSBBBP0000000027696.579595.5734
ENSG00000137834homo_sapiensENSP0000028884097.580697.1774monodon_monocerosENSMMNP0001501060597.777897.3737
ENSG00000137834homo_sapiensENSP0000028884096.774296.371sus_scrofaENSSSCP0000000532596.774296.371
ENSG00000137834homo_sapiensENSP0000028884097.782397.379microcebus_murinusENSMICP0000004426497.782397.379
ENSG00000137834homo_sapiensENSP0000028884094.959792.7419octodon_degusENSODEP0000002216593.824791.6335
ENSG00000137834homo_sapiensENSP0000028884094.758193.75jaculus_jaculusENSJJAP0000001832893.439492.4453
ENSG00000137834homo_sapiensENSP0000028884096.975895.9677ovis_aries_rambouilletENSOARP0002001074896.780795.7747
ENSG00000137834homo_sapiensENSP0000028884067.741966.9355ochotona_princepsENSOPRP0000001367198.245697.076
ENSG00000137834homo_sapiensENSP0000028884097.580697.1774delphinapterus_leucasENSDLEP0000001451397.777897.3737
ENSG00000137834homo_sapiensENSP0000028884097.580697.1774physeter_catodonENSPCTP0000502518197.777897.3737
ENSG00000137834homo_sapiensENSP0000028884094.556493.3468mus_caroliMGP_CAROLIEiJ_P008827794.556493.3468
ENSG00000137834homo_sapiensENSP0000028884094.556493.5484mus_musculusENSMUSP0000003628594.747593.7374
ENSG00000137834homo_sapiensENSP0000028884076.008173.9919dipodomys_ordiiENSDORP0000002452794.01591.5212
ENSG00000137834homo_sapiensENSP0000028884097.177496.5726mustela_putorius_furoENSMPUP0000000030597.570896.9636
ENSG00000137834homo_sapiensENSP0000028884097.983996.9758aotus_nancymaaeENSANAP0000000520398.380697.3684
ENSG00000137834homo_sapiensENSP0000028884044.959744.5564saimiri_boliviensis_boliviensisENSSBOP0000001107196.120795.2586
ENSG00000137834homo_sapiensENSP0000028884099.395299.3952chlorocebus_sabaeusENSCSAP0000000941599.395299.3952
ENSG00000137834homo_sapiensENSP0000028884031.854830.6452tupaia_belangeriENSTBEP0000000112358.088255.8824
ENSG00000137834homo_sapiensENSP0000028884094.959793.9516mesocricetus_auratusENSMAUP0000000843694.959793.9516
ENSG00000137834homo_sapiensENSP0000028884097.177496.7742phocoena_sinusENSPSNP0000000300997.768897.3631
ENSG00000137834homo_sapiensENSP0000028884043.548440.121camelus_dromedariusENSCDRP0000500390857.653.0667
ENSG00000137834homo_sapiensENSP0000028884094.959793.75rattus_norvegicusENSRNOP0000001215595.151593.9394
ENSG00000137834homo_sapiensENSP0000028884098.588798.3871prolemur_simusENSPSMP0000000115997.99697.7956
ENSG00000137834homo_sapiensENSP0000028884095.564594.7581microtus_ochrogasterENSMOCP0000001518395.564594.7581
ENSG00000137834homo_sapiensENSP0000028884095.362994.5564peromyscus_maniculatus_bairdiiENSPEMP0000001844695.17194.3662
ENSG00000137834homo_sapiensENSP0000028884045.564545.1613bos_mutusENSBMUP0000000775784.962484.2105
ENSG00000137834homo_sapiensENSP0000028884094.354893.3468mus_spicilegusENSMSIP0000000403794.16593.159
ENSG00000137834homo_sapiensENSP0000028884094.556493.3468cricetulus_griseus_chok1gshdENSCGRP0000100248494.556493.3468
ENSG00000137834homo_sapiensENSP0000028884096.572696.5726pteropus_vampyrusENSPVAP0000000162595.418395.4183
ENSG00000137834homo_sapiensENSP0000028884083.87181.0484vombatus_ursinusENSVURP0001002283583.280.4
ENSG00000137834homo_sapiensENSP0000028884097.580697.379rhinolophus_ferrumequinumENSRFEP0001000566997.580697.379
ENSG00000137834homo_sapiensENSP0000028884097.177496.5726neovison_visonENSNVIP0000002076897.373796.7677
ENSG00000137834homo_sapiensENSP0000028884096.774295.7661bos_taurusENSBTAP0000000082490.737289.7921
ENSG00000137834homo_sapiensENSP0000028884094.959792.3387heterocephalus_glaber_femaleENSHGLP0000005779887.06184.658
ENSG00000137834homo_sapiensENSP0000028884090.725890.7258rhinopithecus_bietiENSRBIP0000003029399.557599.5575
ENSG00000137834homo_sapiensENSP0000028884096.37195.5645canis_lupus_dingoENSCAFP0002001008195.791694.99
ENSG00000137834homo_sapiensENSP0000028884096.774295.9677sciurus_vulgarisENSSVLP0000503170297.363196.5517
ENSG00000137834homo_sapiensENSP0000028884083.87181.0484phascolarctos_cinereusENSPCIP0000000817283.280.4
ENSG00000137834homo_sapiensENSP0000028884090.322688.7097procavia_capensisENSPCAP0000000398990.322688.7097
ENSG00000137834homo_sapiensENSP0000028884094.556493.9516nannospalax_galiliENSNGAP0000002230094.366293.7626
ENSG00000137834homo_sapiensENSP0000028884096.774295.7661bos_grunniensENSBGRP0000003831290.737289.7921
ENSG00000137834homo_sapiensENSP0000028884043.7541.9355chinchilla_lanigeraENSCLAP0000000791990.416786.6667
ENSG00000137834homo_sapiensENSP0000028884097.177496.1694cervus_hanglu_yarkandensisENSCHYP0000001706796.495.4
ENSG00000137834homo_sapiensENSP0000028884096.975896.7742catagonus_wagneriENSCWAP0000001964396.780796.5795
ENSG00000137834homo_sapiensENSP0000028884097.983997.5806ictidomys_tridecemlineatusENSSTOP0000000062297.983997.5806
ENSG00000137834homo_sapiensENSP0000028884095.967795.5645otolemur_garnettiiENSOGAP0000001377896.551796.146
ENSG00000137834homo_sapiensENSP0000028884095.967794.3548cebus_imitatorENSCCAP0000001816597.341595.7055
ENSG00000137834homo_sapiensENSP0000028884097.782397.379urocitellus_parryiiENSUPAP0001002274597.782397.379
ENSG00000137834homo_sapiensENSP0000028884096.169495.1613moschus_moschiferusENSMMSP0000000183595.975994.9698
ENSG00000137834homo_sapiensENSP0000028884045.362945.3629rhinopithecus_roxellanaENSRROP0000003991199.557599.5575
ENSG00000137834homo_sapiensENSP0000028884094.153293.1452mus_pahariMGP_PahariEiJ_P002392394.343493.3333
ENSG00000137834homo_sapiensENSP0000028884098.387197.7823propithecus_coquereliENSPCOP0000000173097.697
ENSG00000137834homo_sapiensENSP0000028884027.217716.3306caenorhabditis_elegansF01G10.8b.140.785524.4713
ENSG00000137834homo_sapiensENSP0000028884020.362914.3145ciona_intestinalisENSCINP0000001228729.360520.6395
ENSG00000137834homo_sapiensENSP0000028884045.967739.3145petromyzon_marinusENSPMAP0000000912867.455657.6923
ENSG00000137834homo_sapiensENSP0000028884047.782338.5081eptatretus_burgeriENSEBUP0000002275857.804946.5854
ENSG00000137834homo_sapiensENSP0000028884031.048428.4274callorhinchus_miliiENSCMIP0000002162687.580.1136
ENSG00000137834homo_sapiensENSP0000028884071.774263.3064latimeria_chalumnaeENSLACP0000000604373.402164.7423
ENSG00000137834homo_sapiensENSP0000028884072.37963.9113lepisosteus_oculatusENSLOCP0000001713073.716665.0924
ENSG00000137834homo_sapiensENSP0000028884066.532356.6532clupea_harengusENSCHAP0000005193566.937156.998
ENSG00000137834homo_sapiensENSP0000028884030.645228.2258clupea_harengusENSCHAP0000005190380.423374.0741
ENSG00000137834homo_sapiensENSP0000028884066.330655.8468clupea_harengusENSCHAP0000005385267.835157.1134
ENSG00000137834homo_sapiensENSP0000028884071.975862.7016danio_rerioENSDARP0000009134273.456863.9918
ENSG00000137834homo_sapiensENSP0000028884062.701652.621danio_rerioENSDARP0000011240868.201857.2368
ENSG00000137834homo_sapiensENSP0000028884059.87950carassius_auratusENSCARP0000010877465.562954.7461
ENSG00000137834homo_sapiensENSP0000028884071.975862.7016carassius_auratusENSCARP0000011133773.30663.8604
ENSG00000137834homo_sapiensENSP0000028884061.895251.4113carassius_auratusENSCARP0000012274767.324655.9211
ENSG00000137834homo_sapiensENSP0000028884031.048427.0161carassius_auratusENSCARP000000768827767
ENSG00000137834homo_sapiensENSP0000028884072.177462.9032carassius_auratusENSCARP0000003134973.966964.4628
ENSG00000137834homo_sapiensENSP0000028884058.87148.5887astyanax_mexicanusENSAMXP0000000635162.393251.4957
ENSG00000137834homo_sapiensENSP0000028884068.7561.4919astyanax_mexicanusENSAMXP0000000295471.041763.5417
ENSG00000137834homo_sapiensENSP0000028884058.669448.9919ictalurus_punctatusENSIPUP0000002891663.676153.1729
ENSG00000137834homo_sapiensENSP0000028884068.548460.6855ictalurus_punctatusENSIPUP0000003218569.672161.6803
ENSG00000137834homo_sapiensENSP0000028884066.733956.0484esox_luciusENSELUP0000004309163.653853.4615
ENSG00000137834homo_sapiensENSP0000028884064.314554.8387esox_luciusENSELUP0000002208062.795353.5433
ENSG00000137834homo_sapiensENSP0000028884071.774262.2984electrophorus_electricusENSEEEP0000001955572.653163.0612
ENSG00000137834homo_sapiensENSP0000028884060.483949.5968electrophorus_electricusENSEEEP0000004277564.655253.0172
ENSG00000137834homo_sapiensENSP0000028884063.104854.2339oncorhynchus_kisutchENSOKIP0000504826263.617954.6748
ENSG00000137834homo_sapiensENSP0000028884057.056447.5806oncorhynchus_kisutchENSOKIP0000507198558.110948.46
ENSG00000137834homo_sapiensENSP0000028884025.806521.1694oncorhynchus_kisutchENSOKIP0000509007681.012766.4557
ENSG00000137834homo_sapiensENSP0000028884064.919454.8387oncorhynchus_mykissENSOMYP0000013268561.923152.3077
ENSG00000137834homo_sapiensENSP0000028884063.709754.0323oncorhynchus_mykissENSOMYP0000007578864.227654.4715
ENSG00000137834homo_sapiensENSP0000028884065.12155.0403oncorhynchus_mykissENSOMYP0000010879962.115452.5
ENSG00000137834homo_sapiensENSP0000028884062.903254.0323salmo_salarENSSSAP0000009728363.673554.6939
ENSG00000137834homo_sapiensENSP0000028884064.717754.6371salmo_salarENSSSAP0000016268161.259551.7176
ENSG00000137834homo_sapiensENSP0000028884065.322655.0403salmo_salarENSSSAP0000016561661.832152.0992
ENSG00000137834homo_sapiensENSP0000028884033.266126.0081salmo_truttaENSSTUP0000008433249.107138.3929
ENSG00000137834homo_sapiensENSP0000028884027.217722.9839salmo_truttaENSSTUP0000006872380.357167.8571
ENSG00000137834homo_sapiensENSP0000028884030.241927.0161salmo_truttaENSSTUP0000003218778.947470.5263
ENSG00000137834homo_sapiensENSP0000028884039.717732.6613salmo_truttaENSSTUP0000002477856.44746.4183
ENSG00000137834homo_sapiensENSP0000028884043.145232.8629salmo_truttaENSSTUP0000003226547.03335.8242
ENSG00000137834homo_sapiensENSP0000028884072.177462.9032gadus_morhuaENSGMOP0000000894871.743562.5251
ENSG00000137834homo_sapiensENSP0000028884061.895248.9919gadus_morhuaENSGMOP0000002795159.152246.8208
ENSG00000137834homo_sapiensENSP0000028884060.080648.7903fundulus_heteroclitusENSFHEP0000002257359.244548.1113
ENSG00000137834homo_sapiensENSP0000028884072.580662.9032fundulus_heteroclitusENSFHEP0000001988173.170763.4146
ENSG00000137834homo_sapiensENSP0000028884072.782363.3064poecilia_reticulataENSPREP0000001581372.635863.1791
ENSG00000137834homo_sapiensENSP0000028884051.411342.7419poecilia_reticulataENSPREP0000001214076.807263.8554
ENSG00000137834homo_sapiensENSP0000028884072.983963.7097xiphophorus_maculatusENSXMAP0000000355873.577264.2276
ENSG00000137834homo_sapiensENSP0000028884060.080649.3952xiphophorus_maculatusENSXMAP0000000236858.777148.3235
ENSG00000137834homo_sapiensENSP0000028884071.37162.0968oryzias_latipesENSORLP0000000857272.54163.1148
ENSG00000137834homo_sapiensENSP0000028884060.282349.7984oryzias_latipesENSORLP0000000276759.919849.499
ENSG00000137834homo_sapiensENSP0000028884072.177463.5081cyclopterus_lumpusENSCLMP0000504271772.912464.1548
ENSG00000137834homo_sapiensENSP0000028884061.895249.7984cyclopterus_lumpusENSCLMP0000504500260.552348.7179
ENSG00000137834homo_sapiensENSP0000028884071.572663.3064oreochromis_niloticusENSONIP0000003607772.745964.3443
ENSG00000137834homo_sapiensENSP0000028884061.491949.7984oreochromis_niloticusENSONIP0000001670360.878249.3014
ENSG00000137834homo_sapiensENSP0000028884071.37163.3064haplochromis_burtoniENSHBUP0000001100972.54164.3443
ENSG00000137834homo_sapiensENSP0000028884061.693649.7984haplochromis_burtoniENSHBUP0000001054761.077849.3014
ENSG00000137834homo_sapiensENSP0000028884061.491949.7984astatotilapia_callipteraENSACLP0000002397160.878249.3014
ENSG00000137834homo_sapiensENSP0000028884071.169462.9032astatotilapia_callipteraENSACLP0000002217072.336163.9344
ENSG00000137834homo_sapiensENSP0000028884061.491949.1936sparus_aurataENSSAUP0001000260260.276748.2213
ENSG00000137834homo_sapiensENSP0000028884072.580663.7097sparus_aurataENSSAUP0001002679673.319864.3585
ENSG00000137834homo_sapiensENSP0000028884072.782363.9113lates_calcariferENSLCAP0001002643873.523464.5621
ENSG00000137834homo_sapiensENSP0000028884061.895250.8064lates_calcariferENSLCAP0001000205460.671949.8024
ENSG00000137834homo_sapiensENSP0000028884056.854849.7984xenopus_tropicalisENSXETP0000003478380.113670.1705
ENSG00000137834homo_sapiensENSP0000028884073.387168.3468chrysemys_picta_belliiENSCPBP0000003684673.833768.7627
ENSG00000137834homo_sapiensENSP0000028884069.354864.7177sphenodon_punctatusENSSPUP0000001743182.891677.3494
ENSG00000137834homo_sapiensENSP0000028884043.346835.8871crocodylus_porosusENSCPRP0000500090257.333347.4667
ENSG00000137834homo_sapiensENSP0000028884046.169434.879laticauda_laticaudataENSLLTP0000000471967.155450.7331
ENSG00000137834homo_sapiensENSP0000028884042.137134.879notechis_scutatusENSNSUP0000000078450.728241.9903
ENSG00000137834homo_sapiensENSP0000028884064.314558.2661pseudonaja_textilisENSPTXP0000002246377.804970.4878
ENSG00000137834homo_sapiensENSP0000028884070.564566.3306anas_platyrhynchos_platyrhynchosENSAPLP0000000041172.016567.6955
ENSG00000137834homo_sapiensENSP0000028884069.758164.7177gallus_gallusENSGALP0001002597880.278474.478
ENSG00000137834homo_sapiensENSP0000028884043.548439.7177meleagris_gallopavoENSMGAP0000001021879.704872.6937
ENSG00000137834homo_sapiensENSP0000028884052.62149.3952serinus_canariaENSSCAP0000001413288.175782.7703
ENSG00000137834homo_sapiensENSP0000028884052.62149.3952parus_majorENSPMJP0000001304788.175782.7703
ENSG00000137834homo_sapiensENSP0000028884062.298456.25anolis_carolinensisENSACAP0000000970274.100766.9065
ENSG00000137834homo_sapiensENSP0000028884055.846844.9597neolamprologus_brichardiENSNBRP0000002889460.879149.011
ENSG00000137834homo_sapiensENSP0000028884071.37163.3064neolamprologus_brichardiENSNBRP0000002054972.54164.3443
ENSG00000137834homo_sapiensENSP0000028884067.741961.8952naja_najaENSNNAP0000001672985.279277.9188
ENSG00000137834homo_sapiensENSP0000028884071.774266.9355podarcis_muralisENSPMRP0000002249570.634965.873
ENSG00000137834homo_sapiensENSP0000028884051.612946.371geospiza_fortisENSGFOP0000001748080.503172.327
ENSG00000137834homo_sapiensENSP0000028884073.185567.1371taeniopygia_guttataENSTGUP0000000975176.100669.8113
ENSG00000137834homo_sapiensENSP0000028884059.677453.629erpetoichthys_calabaricusENSECRP0000002780675.510267.8571
ENSG00000137834homo_sapiensENSP0000028884071.169463.5081kryptolebias_marmoratusENSKMAP0000002655572.933965.0826
ENSG00000137834homo_sapiensENSP0000028884059.87947.9839kryptolebias_marmoratusENSKMAP0000001581357.005845.6814
ENSG00000137834homo_sapiensENSP0000028884073.387165.9274salvator_merianaeENSSMRP0000002805074.134466.5988
ENSG00000137834homo_sapiensENSP0000028884059.677449.5968oryzias_javanicusENSOJAP0000004124459.79849.697
ENSG00000137834homo_sapiensENSP0000028884071.774262.5oryzias_javanicusENSOJAP0000002563573.402163.9175
ENSG00000137834homo_sapiensENSP0000028884028.225822.7823amphilophus_citrinellusENSACIP0000000767181.395365.6977
ENSG00000137834homo_sapiensENSP0000028884058.064552.2177amphilophus_citrinellusENSACIP0000000509785.970177.3134
ENSG00000137834homo_sapiensENSP0000028884062.298449.5968dicentrarchus_labraxENSDLAP0000502745261.188148.7129
ENSG00000137834homo_sapiensENSP0000028884072.37963.5081dicentrarchus_labraxENSDLAP0000506767273.116164.1548
ENSG00000137834homo_sapiensENSP0000028884060.483949.5968amphiprion_perculaENSAPEP0000000071059.642148.9066
ENSG00000137834homo_sapiensENSP0000028884072.580664.1129amphiprion_perculaENSAPEP0000002967573.770565.1639
ENSG00000137834homo_sapiensENSP0000028884040.725832.8629oryzias_sinensisENSOSIP0000004768161.963250
ENSG00000137834homo_sapiensENSP0000028884033.266130.2419oryzias_sinensisENSOSIP0000004770287.76679.7872
ENSG00000137834homo_sapiensENSP0000028884060.080649.5968oryzias_sinensisENSOSIP0000001014659.719449.2986
ENSG00000137834homo_sapiensENSP0000028884038.911336.6936gopherus_evgoodeiENSGEVP0000500723390.610385.446
ENSG00000137834homo_sapiensENSP0000028884038.709736.4919chelonoidis_abingdoniiENSCABP0000002199290.140884.9765
ENSG00000137834homo_sapiensENSP0000028884072.580664.1129seriola_dumeriliENSSDUP0000001093273.319864.7658
ENSG00000137834homo_sapiensENSP0000028884060.685550.2016seriola_dumeriliENSSDUP0000002348258.904148.728
ENSG00000137834homo_sapiensENSP0000028884061.895249.5968cottoperca_gobioENSCGOP0000002393860.196148.2353
ENSG00000137834homo_sapiensENSP0000028884070.564562.0968cottoperca_gobioENSCGOP0000003145972.765164.0333
ENSG00000137834homo_sapiensENSP0000028884040.927438.9113anser_brachyrhynchusENSABRP0000000951788.260983.913
ENSG00000137834homo_sapiensENSP0000028884072.177463.9113gasterosteus_aculeatusENSGACP0000000671672.912464.5621
ENSG00000137834homo_sapiensENSP0000028884060.685549.1936gasterosteus_aculeatusENSGACP0000002229558.108147.1042
ENSG00000137834homo_sapiensENSP0000028884072.177462.2984cynoglossus_semilaevisENSCSEP0000001099672.912462.9328
ENSG00000137834homo_sapiensENSP0000028884060.080649.5968cynoglossus_semilaevisENSCSEP0000001974654.379644.8905
ENSG00000137834homo_sapiensENSP0000028884059.677449.7984poecilia_formosaENSPFOP0000000618058.49848.8142
ENSG00000137834homo_sapiensENSP0000028884072.37963.3064poecilia_formosaENSPFOP0000000873273.265364.0816
ENSG00000137834homo_sapiensENSP0000028884060.282350.2016myripristis_murdjanENSMMDP0000502836564.025753.3191
ENSG00000137834homo_sapiensENSP0000028884073.185564.1129myripristis_murdjanENSMMDP0000501960273.930864.7658
ENSG00000137834homo_sapiensENSP0000028884071.169463.5081sander_luciopercaENSSLUP0000000055673.541765.625
ENSG00000137834homo_sapiensENSP0000028884061.895250.4032sander_luciopercaENSSLUP0000004319961.033849.7018
ENSG00000137834homo_sapiensENSP0000028884072.782366.9355strigops_habroptilaENSSHBP0000500082873.975468.0328
ENSG00000137834homo_sapiensENSP0000028884060.483949.5968amphiprion_ocellarisENSAOCP0000001099259.405948.7129
ENSG00000137834homo_sapiensENSP0000028884072.782364.3145amphiprion_ocellarisENSAOCP0000000078473.975465.3689
ENSG00000137834homo_sapiensENSP0000028884072.782367.7419terrapene_carolina_triunguisENSTMTP0000001161073.076968.0162
ENSG00000137834homo_sapiensENSP0000028884034.87928.629hucho_huchoENSHHUP0000001896252.743943.2927
ENSG00000137834homo_sapiensENSP0000028884061.290352.0161hucho_huchoENSHHUP0000002071565.096455.2463
ENSG00000137834homo_sapiensENSP0000028884037.096829.6371betta_splendensENSBSLP0000003100659.354847.4194
ENSG00000137834homo_sapiensENSP0000028884072.983964.1129betta_splendensENSBSLP0000003385873.727164.7658
ENSG00000137834homo_sapiensENSP0000028884068.7561.8952pygocentrus_nattereriENSPNAP0000002871673.019365.7388
ENSG00000137834homo_sapiensENSP0000028884064.717755.2419pygocentrus_nattereriENSPNAP0000000894465.778756.1475
ENSG00000137834homo_sapiensENSP0000028884072.983964.1129anabas_testudineusENSATEP0000001404073.727164.7658
ENSG00000137834homo_sapiensENSP0000028884060.080649.3952anabas_testudineusENSATEP0000002686059.244548.7078
ENSG00000137834homo_sapiensENSP0000028884061.290350.6048seriola_lalandi_dorsalisENSSLDP0000001309059.72549.3124
ENSG00000137834homo_sapiensENSP0000028884072.580664.1129seriola_lalandi_dorsalisENSSLDP0000003059473.319864.7658
ENSG00000137834homo_sapiensENSP0000028884071.169463.1048labrus_bergyltaENSLBEP0000001997271.894163.7475
ENSG00000137834homo_sapiensENSP0000028884060.887149.5968labrus_bergyltaENSLBEP0000002468059.683848.6166
ENSG00000137834homo_sapiensENSP0000028884071.37163.3064pundamilia_nyerereiENSPNYP0000001913972.54164.3443
ENSG00000137834homo_sapiensENSP0000028884061.693649.7984pundamilia_nyerereiENSPNYP0000001044361.077849.3014
ENSG00000137834homo_sapiensENSP0000028884060.282349.5968mastacembelus_armatusENSMAMP0000001795959.561849.004
ENSG00000137834homo_sapiensENSP0000028884072.580663.9113mastacembelus_armatusENSMAMP0000000882773.319864.5621
ENSG00000137834homo_sapiensENSP0000028884061.290350.4032stegastes_partitusENSSPAP0000002578860.437449.7018
ENSG00000137834homo_sapiensENSP0000028884073.185564.5161stegastes_partitusENSSPAP0000002528474.385265.5738
ENSG00000137834homo_sapiensENSP0000028884026.814521.9758oncorhynchus_tshawytschaENSOTSP0000504899781.097666.4634
ENSG00000137834homo_sapiensENSP0000028884038.508129.8387oncorhynchus_tshawytschaENSOTSP0000503377545.693835.4067
ENSG00000137834homo_sapiensENSP0000028884035.483929.2339oncorhynchus_tshawytschaENSOTSP0000503382657.894747.6974
ENSG00000137834homo_sapiensENSP0000028884030.040326.8145oncorhynchus_tshawytschaENSOTSP0000504548378.421170
ENSG00000137834homo_sapiensENSP0000028884060.685549.7984acanthochromis_polyacanthusENSAPOP0000002979758.560348.0545
ENSG00000137834homo_sapiensENSP0000028884072.37964.1129acanthochromis_polyacanthusENSAPOP0000002552173.565665.1639
ENSG00000137834homo_sapiensENSP0000028884072.782366.9355aquila_chrysaetos_chrysaetosENSACCP0002000072972.266.4
ENSG00000137834homo_sapiensENSP0000028884059.072646.9758nothobranchius_furzeriENSNFUP0001502148656.782945.155
ENSG00000137834homo_sapiensENSP0000028884045.161338.1048nothobranchius_furzeriENSNFUP0001501725465.497155.2632
ENSG00000137834homo_sapiensENSP0000028884071.975862.9032cyprinodon_variegatusENSCVAP0000002403272.56163.4146
ENSG00000137834homo_sapiensENSP0000028884059.475848.7903cyprinodon_variegatusENSCVAP000000250405948.4
ENSG00000137834homo_sapiensENSP0000028884059.475852.4194denticeps_clupeoidesENSDCDP0000001310274.494965.6566
ENSG00000137834homo_sapiensENSP0000028884054.233947.7823denticeps_clupeoidesENSDCDP0000001330373.497364.7541
ENSG00000137834homo_sapiensENSP0000028884053.830646.7742denticeps_clupeoidesENSDCDP0000003318977.616367.4419
ENSG00000137834homo_sapiensENSP0000028884061.491949.5968larimichthys_croceaENSLCRP0000501336860.276748.6166
ENSG00000137834homo_sapiensENSP0000028884072.37963.7097larimichthys_croceaENSLCRP0000502220273.116164.3585
ENSG00000137834homo_sapiensENSP0000028884028.427422.5806takifugu_rubripesENSTRUP0000006011081.034564.3678
ENSG00000137834homo_sapiensENSP0000028884059.072646.371takifugu_rubripesENSTRUP0000004798459.191946.4646
ENSG00000137834homo_sapiensENSP0000028884070.564562.2984takifugu_rubripesENSTRUP0000005316071.283162.9328
ENSG00000137834homo_sapiensENSP0000028884054.637148.7903ficedula_albicollisENSFALP0000001340870.207362.6943
ENSG00000137834homo_sapiensENSP0000028884027.822621.5726hippocampus_comesENSHCOP0000000721579.768861.8497
ENSG00000137834homo_sapiensENSP0000028884071.572662.5hippocampus_comesENSHCOP0000001205873.804664.4491
ENSG00000137834homo_sapiensENSP0000028884068.346859.4758cyprinus_carpio_carpioENSCCRP0000005334772.435963.0342
ENSG00000137834homo_sapiensENSP0000028884062.096851.2097cyprinus_carpio_carpioENSCCRP0000017339267.543955.7018
ENSG00000137834homo_sapiensENSP0000028884061.895250.8064cyprinus_carpio_carpioENSCCRP0000012108565.319153.617
ENSG00000137834homo_sapiensENSP0000028884072.37963.1048cyprinus_carpio_carpioENSCCRP0000003168373.716664.271
ENSG00000137834homo_sapiensENSP0000028884069.758164.7177coturnix_japonicaENSCJPP0000502698580.092674.3056
ENSG00000137834homo_sapiensENSP0000028884051.209742.7419poecilia_latipinnaENSPLAP0000002494176.50663.8554
ENSG00000137834homo_sapiensENSP0000028884072.580663.5081poecilia_latipinnaENSPLAP0000001103073.469464.2857
ENSG00000137834homo_sapiensENSP0000028884061.491950.2016sinocyclocheilus_grahamiENSSGRP0000007022667.180654.8458
ENSG00000137834homo_sapiensENSP0000028884071.169461.6936sinocyclocheilus_grahamiENSSGRP0000010817572.336162.7049
ENSG00000137834homo_sapiensENSP0000028884061.088750.4032sinocyclocheilus_grahamiENSSGRP0000000465867.333355.5556
ENSG00000137834homo_sapiensENSP0000028884071.774262.0968sinocyclocheilus_grahamiENSSGRP0000004933773.100663.2444
ENSG00000137834homo_sapiensENSP0000028884061.491949.7984maylandia_zebraENSMZEP0000501645260.878249.3014
ENSG00000137834homo_sapiensENSP0000028884071.169462.9032maylandia_zebraENSMZEP0000503043872.336163.9344
ENSG00000137834homo_sapiensENSP0000028884031.451628.8306tetraodon_nigroviridisENSTNIP0000001126788.135680.791
ENSG00000137834homo_sapiensENSP0000028884056.854844.9597tetraodon_nigroviridisENSTNIP0000001241861.572148.69
ENSG00000137834homo_sapiensENSP0000028884071.37162.0968paramormyrops_kingsleyaeENSPKIP0000003768467.172758.444
ENSG00000137834homo_sapiensENSP0000028884073.588766.3306scleropages_formosusENSSFOP0001506627671.150164.1326
ENSG00000137834homo_sapiensENSP0000028884055.846848.1855leptobrachium_leishanenseENSLLEP0000001429278.693267.8977
ENSG00000137834homo_sapiensENSP0000028884062.096851.6129scophthalmus_maximusENSSMAP0000003484560.03949.9025
ENSG00000137834homo_sapiensENSP0000028884071.774263.1048scophthalmus_maximusENSSMAP0000002366572.505163.7475
ENSG00000137834homo_sapiensENSP0000028884071.774262.2984oryzias_melastigmaENSOMEP0000001833973.402163.7113
ENSG00000137834homo_sapiensENSP0000028884059.87949.7984oryzias_melastigmaENSOMEP000000268806049.899

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000785part_of chromatin1ISAHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0001657involved_in ureteric bud development1IEAHomo_sapiens(9606)Process
GO:0003148involved_in outflow tract septum morphogenesis1ISSHomo_sapiens(9606)Process
GO:0003180involved_in aortic valve morphogenesis1IMPHomo_sapiens(9606)Process
GO:0003183involved_in mitral valve morphogenesis1ISSHomo_sapiens(9606)Process
GO:0003184involved_in pulmonary valve morphogenesis1ISSHomo_sapiens(9606)Process
GO:0003281involved_in ventricular septum development1IEAHomo_sapiens(9606)Process
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1TASHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0006955involved_in immune response1IMPHomo_sapiens(9606)Process
GO:0007179involved_in transforming growth factor beta receptor signaling pathway1IBAHomo_sapiens(9606)Process
GO:0007352involved_in zygotic specification of dorsal/ventral axis1IMPHomo_sapiens(9606)Process
GO:0008285involved_in negative regulation of cell population proliferation1IMPHomo_sapiens(9606)Process
GO:0009653involved_in anatomical structure morphogenesis1IBAHomo_sapiens(9606)Process
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0030154involved_in cell differentiation1IBAHomo_sapiens(9606)Process
GO:0030279involved_in negative regulation of ossification1ISSHomo_sapiens(9606)Process
GO:0030509involved_in BMP signaling pathway2IBA,IDAHomo_sapiens(9606)Process
GO:0030512involved_in negative regulation of transforming growth factor beta receptor signaling pathway2IDA,IMPHomo_sapiens(9606)Process
GO:0030514involved_in negative regulation of BMP signaling pathway2IDA,IMPHomo_sapiens(9606)Process
GO:0031589involved_in cell-substrate adhesion1IMPHomo_sapiens(9606)Process
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032496involved_in response to lipopolysaccharide1IDAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0034616involved_in response to laminar fluid shear stress1IEPHomo_sapiens(9606)Process
GO:0034713enables type I transforming growth factor beta receptor binding1IDAHomo_sapiens(9606)Function
GO:0035904involved_in aorta development1IEAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0043627involved_in response to estrogen1IEAHomo_sapiens(9606)Process
GO:0045444involved_in fat cell differentiation1IDAHomo_sapiens(9606)Process
GO:0045668involved_in negative regulation of osteoblast differentiation1IMPHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0060394involved_in negative regulation of pathway-restricted SMAD protein phosphorylation2IDA,IMPHomo_sapiens(9606)Process
GO:0060395involved_in SMAD protein signal transduction1IBAHomo_sapiens(9606)Process
GO:0060976involved_in coronary vasculature development1IEAHomo_sapiens(9606)Process
GO:0070410enables co-SMAD binding1IPIHomo_sapiens(9606)Function
GO:0070411enables I-SMAD binding2IBA,IPIHomo_sapiens(9606)Function
GO:0070412enables R-SMAD binding1IPIHomo_sapiens(9606)Function
GO:0070698enables type I activin receptor binding1IDAHomo_sapiens(9606)Function
GO:0071144part_of heteromeric SMAD protein complex1IBAHomo_sapiens(9606)Component
GO:0140416enables transcription regulator inhibitor activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:1902895involved_in positive regulation of miRNA transcription1IEAHomo_sapiens(9606)Process

Expression