RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	tRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000137760	Gene ID	91801	Accession	25189
Symbol	ALKBH8	Alias	ABH8;TRM9;MRT71;TRMT9;TRMT9A	Full Name	alkB homolog 8, tRNA methyltransferase
Status	Confidence	Length	63016 bases	Strand	Minus strand
Position	11 : 107502727 - 107565742	RNA binding domain	2OG-FeII_Oxy_2 , RRM_1 , ALKBH8_N
Summary	Enables tRNA (uracil) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Involved in cellular response to DNA damage stimulus; tRNA methylation; and tRNA wobble uridine modification. Located in cytosol and nuclear body. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000376812	RRM_1	PF00076	0.00012	1
ENSP00000376812	ALKBH8_N	PF09004	3.8e-15	2
ENSP00000391225	RRM_1	PF00076	0.00033	1
ENSP00000391225	ALKBH8_N	PF09004	5.7e-15	2
ENSP00000260318	RRM_1	PF00076	0.00037	1
ENSP00000260318	ALKBH8_N	PF09004	7.5e-15	2
ENSP00000374219	2OG-FeII_Oxy_2	PF13532	4.3e-20	1
ENSP00000374219	ALKBH8_N	PF09004	3e-14	2
ENSP00000397673	2OG-FeII_Oxy_2	PF13532	4.3e-20	1
ENSP00000397673	ALKBH8_N	PF09004	3e-14	2
ENSP00000415885	2OG-FeII_Oxy_2	PF13532	4.3e-20	1
ENSP00000415885	ALKBH8_N	PF09004	3e-14	2

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
26147969	Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.	Lauren Endres	2015-01-01	PloS one
36192131	HITS-CLIP analysis of human ALKBH8 reveals interactions with fully processed substrate tRNAs and with specific noncoding RNAs.	Ivana Cavallin	2022-12-01	RNA (New York, N.Y.)
24489119	Structure of human RNA N⁶-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.	WeiShen Aik	2014-04-01	Nucleic acids research
24580634	Nucleic acid oxidation in DNA damage repair and epigenetics.	Guanqun Zheng	2014-04-23	Chemical reviews
37007161	The role of demethylase AlkB homologs in cancer.	Qiao Li	2023-01-01	Frontiers in oncology
31996211	Case report: recurrent pituitary adenoma has increased load of somatic variants.	Raitis Peculis	2020-01-29	BMC endocrine disorders
35040547	Spectroscopic and in vitro Investigations of Fe2+ /α-Ketoglutarate-Dependent Enzymes Involved in Nucleic Acid Repair and Modification.	David Schmidl	2022-06-03	Chembiochem : a European journal of chemical biology

Name	Transcript ID	bp	Protein	Translation ID
ALKBH8-205	ENST00000428149	4067	664aa	ENSP00000415885
ALKBH8-206	ENST00000429370	2296	224aa	ENSP00000391225
ALKBH8-202	ENST00000389568	2491	664aa	ENSP00000374219
ALKBH8-201	ENST00000260318	1684	238aa	ENSP00000260318
ALKBH8-204	ENST00000417449	2114	664aa	ENSP00000397673
ALKBH8-203	ENST00000393100	999	144aa	ENSP00000376812
ALKBH8-207	ENST00000530933	594	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000137760	homo_sapiens	ENSP00000368152	43.2773	28.5714	homo_sapiens	ENSP00000415885	15.512	10.241
ENSG00000137760	homo_sapiens	ENSP00000432695	38.326	25.3304	homo_sapiens	ENSP00000415885	26.2048	17.3193

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000137760	homo_sapiens	ENSP00000415885	98.494	97.8916	nomascus_leucogenys	ENSNLEP00000008799	98.494	97.8916
ENSG00000137760	homo_sapiens	ENSP00000415885	99.247	98.7952	pan_paniscus	ENSPPAP00000002825	99.247	98.7952
ENSG00000137760	homo_sapiens	ENSP00000415885	98.3434	97.741	pongo_abelii	ENSPPYP00000037353	98.3434	97.741
ENSG00000137760	homo_sapiens	ENSP00000415885	99.0964	98.3434	pan_troglodytes	ENSPTRP00000047669	98.6507	97.901
ENSG00000137760	homo_sapiens	ENSP00000415885	99.0964	98.6446	gorilla_gorilla	ENSGGOP00000015127	99.0964	98.6446
ENSG00000137760	homo_sapiens	ENSP00000415885	82.8313	70.7831	ornithorhynchus_anatinus	ENSOANP00000016578	82.5826	70.5706
ENSG00000137760	homo_sapiens	ENSP00000415885	85.6928	74.6988	sarcophilus_harrisii	ENSSHAP00000035558	83.5536	72.8341
ENSG00000137760	homo_sapiens	ENSP00000415885	76.8072	67.1687	notamacropus_eugenii	ENSMEUP00000013928	76.4618	66.8666
ENSG00000137760	homo_sapiens	ENSP00000415885	60.5422	57.3795	choloepus_hoffmanni	ENSCHOP00000010169	75.4221	71.4822
ENSG00000137760	homo_sapiens	ENSP00000415885	85.5422	78.4639	dasypus_novemcinctus	ENSDNOP00000021624	85.9304	78.82
ENSG00000137760	homo_sapiens	ENSP00000415885	51.0542	47.1386	erinaceus_europaeus	ENSEEUP00000014234	72.7468	67.1674
ENSG00000137760	homo_sapiens	ENSP00000415885	31.6265	27.4096	echinops_telfairi	ENSETEP00000004469	85.3659	73.9837
ENSG00000137760	homo_sapiens	ENSP00000415885	95.6325	92.4699	callithrix_jacchus	ENSCJAP00000042366	92.1626	89.1147
ENSG00000137760	homo_sapiens	ENSP00000415885	93.5241	91.8675	cercocebus_atys	ENSCATP00000024726	97.4882	95.7614
ENSG00000137760	homo_sapiens	ENSP00000415885	98.494	96.988	macaca_fascicularis	ENSMFAP00000033328	93.8307	92.396
ENSG00000137760	homo_sapiens	ENSP00000415885	98.494	96.8373	macaca_mulatta	ENSMMUP00000047462	98.494	96.8373
ENSG00000137760	homo_sapiens	ENSP00000415885	98.7952	97.1386	macaca_nemestrina	ENSMNEP00000037253	98.3508	96.7017
ENSG00000137760	homo_sapiens	ENSP00000415885	98.3434	96.5361	papio_anubis	ENSPANP00000009110	92.4929	90.7932
ENSG00000137760	homo_sapiens	ENSP00000415885	98.1928	96.5361	mandrillus_leucophaeus	ENSMLEP00000011643	98.1928	96.5361
ENSG00000137760	homo_sapiens	ENSP00000415885	83.5843	78.1627	tursiops_truncatus	ENSTTRP00000000222	83.5843	78.1627
ENSG00000137760	homo_sapiens	ENSP00000415885	78.6145	68.8253	vulpes_vulpes	ENSVVUP00000018989	71.7033	62.7747
ENSG00000137760	homo_sapiens	ENSP00000415885	76.0542	68.9759	mus_spretus	MGP_SPRETEiJ_P0090149	85.7385	77.7589
ENSG00000137760	homo_sapiens	ENSP00000415885	93.6747	86.4458	equus_asinus	ENSEASP00005015827	90.5386	83.5517
ENSG00000137760	homo_sapiens	ENSP00000415885	92.7711	86.1446	capra_hircus	ENSCHIP00000004450	92.7711	86.1446
ENSG00000137760	homo_sapiens	ENSP00000415885	87.8012	80.1205	loxodonta_africana	ENSLAFP00000015002	92.1011	84.0442
ENSG00000137760	homo_sapiens	ENSP00000415885	92.3193	84.6386	panthera_leo	ENSPLOP00000029191	92.3193	84.6386
ENSG00000137760	homo_sapiens	ENSP00000415885	89.006	81.4759	ailuropoda_melanoleuca	ENSAMEP00000021919	87.9464	80.506
ENSG00000137760	homo_sapiens	ENSP00000415885	92.6205	85.3916	bos_indicus_hybrid	ENSBIXP00005014665	79.7665	73.5409
ENSG00000137760	homo_sapiens	ENSP00000415885	93.9759	87.3494	equus_caballus	ENSECAP00000017050	91.0949	84.6715
ENSG00000137760	homo_sapiens	ENSP00000415885	90.2108	82.5301	canis_lupus_familiaris	ENSCAFP00845005365	88.0882	80.5882
ENSG00000137760	homo_sapiens	ENSP00000415885	92.3193	84.7892	panthera_pardus	ENSPPRP00000026717	92.3193	84.7892
ENSG00000137760	homo_sapiens	ENSP00000415885	91.7169	85.6928	marmota_marmota_marmota	ENSMMMP00000001086	92.4128	86.3429
ENSG00000137760	homo_sapiens	ENSP00000415885	93.3735	86.5964	balaenoptera_musculus	ENSBMSP00010010328	92.9535	86.2069
ENSG00000137760	homo_sapiens	ENSP00000415885	85.3916	78.3133	felis_catus	ENSFCAP00000035337	91.1576	83.6013
ENSG00000137760	homo_sapiens	ENSP00000415885	18.0723	15.9639	ursus_americanus	ENSUAMP00000028901	82.1918	72.6027
ENSG00000137760	homo_sapiens	ENSP00000415885	80.2711	69.7289	monodelphis_domestica	ENSMODP00000056554	83.6735	72.6845
ENSG00000137760	homo_sapiens	ENSP00000415885	32.0783	28.4639	bison_bison_bison	ENSBBBP00000016769	89.4958	79.4118
ENSG00000137760	homo_sapiens	ENSP00000415885	92.6205	85.5422	monodon_monoceros	ENSMMNP00015020245	86.9873	80.3395
ENSG00000137760	homo_sapiens	ENSP00000415885	80.4217	73.6446	sus_scrofa	ENSSSCP00000020960	86.9707	79.6417
ENSG00000137760	homo_sapiens	ENSP00000415885	94.5783	87.9518	microcebus_murinus	ENSMICP00000000948	94.5783	87.9518
ENSG00000137760	homo_sapiens	ENSP00000415885	89.6084	81.4759	octodon_degus	ENSODEP00000015681	89.7436	81.5988
ENSG00000137760	homo_sapiens	ENSP00000415885	87.3494	79.2169	jaculus_jaculus	ENSJJAP00000020373	87.7458	79.5764
ENSG00000137760	homo_sapiens	ENSP00000415885	90.2108	82.3795	ursus_maritimus	ENSUMAP00000011641	86.9376	79.3904
ENSG00000137760	homo_sapiens	ENSP00000415885	71.5361	64.1566	ochotona_princeps	ENSOPRP00000008778	72.0789	64.6434
ENSG00000137760	homo_sapiens	ENSP00000415885	92.7711	85.6928	delphinapterus_leucas	ENSDLEP00000020058	87.1287	80.4809
ENSG00000137760	homo_sapiens	ENSP00000415885	93.0723	85.6928	physeter_catodon	ENSPCTP00005008386	87.4116	80.4809
ENSG00000137760	homo_sapiens	ENSP00000415885	85.3916	77.1084	mus_musculus	ENSMUSP00000148653	85.3916	77.1084
ENSG00000137760	homo_sapiens	ENSP00000415885	87.1988	79.3675	dipodomys_ordii	ENSDORP00000008068	85.3982	77.7286
ENSG00000137760	homo_sapiens	ENSP00000415885	88.7048	79.2169	mustela_putorius_furo	ENSMPUP00000006026	88.7048	79.2169
ENSG00000137760	homo_sapiens	ENSP00000415885	96.8373	94.8795	aotus_nancymaae	ENSANAP00000020221	96.8373	94.8795
ENSG00000137760	homo_sapiens	ENSP00000415885	97.2892	94.4277	saimiri_boliviensis_boliviensis	ENSSBOP00000030447	97.2892	94.4277
ENSG00000137760	homo_sapiens	ENSP00000415885	84.1867	76.2048	vicugna_pacos	ENSVPAP00000004570	84.5688	76.5507
ENSG00000137760	homo_sapiens	ENSP00000415885	97.5904	96.3855	chlorocebus_sabaeus	ENSCSAP00000015013	97.5904	96.3855
ENSG00000137760	homo_sapiens	ENSP00000415885	82.2289	74.3976	tupaia_belangeri	ENSTBEP00000002360	85.0467	76.947
ENSG00000137760	homo_sapiens	ENSP00000415885	60.8434	53.012	mesocricetus_auratus	ENSMAUP00000025719	76.2264	66.4151
ENSG00000137760	homo_sapiens	ENSP00000415885	92.4699	85.6928	phocoena_sinus	ENSPSNP00000012225	86.8458	80.4809
ENSG00000137760	homo_sapiens	ENSP00000415885	30.4217	25.753	camelus_dromedarius	ENSCDRP00005015579	81.1245	68.6747
ENSG00000137760	homo_sapiens	ENSP00000415885	93.0723	86.8976	carlito_syrichta	ENSTSYP00000006719	92.6537	86.5067
ENSG00000137760	homo_sapiens	ENSP00000415885	92.3193	85.0904	panthera_tigris_altaica	ENSPTIP00000010243	92.3193	85.0904
ENSG00000137760	homo_sapiens	ENSP00000415885	80.1205	72.2892	rattus_norvegicus	ENSRNOP00000072411	84.3106	76.0697
ENSG00000137760	homo_sapiens	ENSP00000415885	94.7289	88.5542	prolemur_simus	ENSPSMP00000015620	94.3028	88.1559
ENSG00000137760	homo_sapiens	ENSP00000415885	84.9398	75.4518	microtus_ochrogaster	ENSMOCP00000022253	84.9398	75.4518
ENSG00000137760	homo_sapiens	ENSP00000415885	75.6024	65.6627	sorex_araneus	ENSSARP00000007556	78.1931	67.9128
ENSG00000137760	homo_sapiens	ENSP00000415885	86.8976	78.7651	peromyscus_maniculatus_bairdii	ENSPEMP00000025665	86.5067	78.4108
ENSG00000137760	homo_sapiens	ENSP00000415885	32.0783	28.3133	bos_mutus	ENSBMUP00000012566	89.4958	78.9916
ENSG00000137760	homo_sapiens	ENSP00000415885	28.6145	25.3012	mus_spicilegus	ENSMSIP00000005148	78.1893	69.1358
ENSG00000137760	homo_sapiens	ENSP00000415885	85.5422	77.5602	cricetulus_griseus_chok1gshd	ENSCGRP00001009101	85.9304	77.9123
ENSG00000137760	homo_sapiens	ENSP00000415885	88.253	80.5723	pteropus_vampyrus	ENSPVAP00000011280	88.253	80.5723
ENSG00000137760	homo_sapiens	ENSP00000415885	55.5723	51.0542	myotis_lucifugus	ENSMLUP00000015332	90.8867	83.4975
ENSG00000137760	homo_sapiens	ENSP00000415885	85.8434	75.6024	vombatus_ursinus	ENSVURP00010018288	84.0708	74.0413
ENSG00000137760	homo_sapiens	ENSP00000415885	92.6205	85.994	rhinolophus_ferrumequinum	ENSRFEP00010013587	93.3232	86.6464
ENSG00000137760	homo_sapiens	ENSP00000415885	88.5542	78.9157	neovison_vison	ENSNVIP00000031642	88.0239	78.4431
ENSG00000137760	homo_sapiens	ENSP00000415885	92.4699	85.5422	bos_taurus	ENSBTAP00000014068	91.5052	84.6498
ENSG00000137760	homo_sapiens	ENSP00000415885	90.3614	83.2831	heterocephalus_glaber_female	ENSHGLP00000039919	90.4977	83.4087
ENSG00000137760	homo_sapiens	ENSP00000415885	98.494	97.4398	rhinopithecus_bieti	ENSRBIP00000017123	98.494	97.4398
ENSG00000137760	homo_sapiens	ENSP00000415885	90.3614	82.6807	canis_lupus_dingo	ENSCAFP00020010969	89.0208	81.454
ENSG00000137760	homo_sapiens	ENSP00000415885	28.7651	25.9036	sciurus_vulgaris	ENSSVLP00005003606	85.2679	76.7857
ENSG00000137760	homo_sapiens	ENSP00000415885	91.2651	84.3373	sciurus_vulgaris	ENSSVLP00005025685	91.2651	84.3373
ENSG00000137760	homo_sapiens	ENSP00000415885	78.6145	71.5361	procavia_capensis	ENSPCAP00000005207	78.733	71.644
ENSG00000137760	homo_sapiens	ENSP00000415885	89.3072	80.7229	nannospalax_galili	ENSNGAP00000016809	88.7725	80.2395
ENSG00000137760	homo_sapiens	ENSP00000415885	92.3193	85.0904	bos_grunniens	ENSBGRP00000026719	90.0147	82.9662
ENSG00000137760	homo_sapiens	ENSP00000415885	91.8675	84.9398	cervus_hanglu_yarkandensis	ENSCHYP00000004011	89.838	83.0633
ENSG00000137760	homo_sapiens	ENSP00000415885	91.2651	83.8855	catagonus_wagneri	ENSCWAP00000007079	90.991	83.6336
ENSG00000137760	homo_sapiens	ENSP00000415885	91.5663	85.5422	ictidomys_tridecemlineatus	ENSSTOP00000019488	92.261	86.1912
ENSG00000137760	homo_sapiens	ENSP00000415885	91.4157	83.8855	otolemur_garnettii	ENSOGAP00000004424	91.4157	83.8855
ENSG00000137760	homo_sapiens	ENSP00000415885	96.5361	94.2771	cebus_imitator	ENSCCAP00000037222	96.6817	94.4193
ENSG00000137760	homo_sapiens	ENSP00000415885	91.7169	85.6928	urocitellus_parryii	ENSUPAP00010009864	92.4128	86.3429
ENSG00000137760	homo_sapiens	ENSP00000415885	91.4157	84.7892	moschus_moschiferus	ENSMMSP00000022454	91.4157	84.7892
ENSG00000137760	homo_sapiens	ENSP00000415885	78.3133	69.7289	moschus_moschiferus	ENSMMSP00000002864	86.3787	76.9103
ENSG00000137760	homo_sapiens	ENSP00000415885	98.494	97.4398	rhinopithecus_roxellana	ENSRROP00000031578	98.494	97.4398
ENSG00000137760	homo_sapiens	ENSP00000415885	80.1205	73.1928	mus_pahari	MGP_PahariEiJ_P0022278	85.6683	78.2609
ENSG00000137760	homo_sapiens	ENSP00000415885	84.9398	80.2711	propithecus_coquereli	ENSPCOP00000021265	91.1147	86.1066
ENSG00000137760	homo_sapiens	ENSP00000415885	49.0964	32.9819	caenorhabditis_elegans	C14B1.10.1	55.1607	37.0558
ENSG00000137760	homo_sapiens	ENSP00000415885	53.4639	39.759	drosophila_melanogaster	FBpp0071849	57.7236	42.9268
ENSG00000137760	homo_sapiens	ENSP00000415885	54.9699	36.2952	ciona_intestinalis	ENSCINP00000019591	60.5307	39.9668
ENSG00000137760	homo_sapiens	ENSP00000415885	67.1687	49.6988	petromyzon_marinus	ENSPMAP00000005072	67.1687	49.6988
ENSG00000137760	homo_sapiens	ENSP00000415885	60.3916	45.9337	eptatretus_burgeri	ENSEBUP00000006039	67.1692	51.0888
ENSG00000137760	homo_sapiens	ENSP00000415885	71.3855	57.0783	callorhinchus_milii	ENSCMIP00000041409	75.5981	60.4466
ENSG00000137760	homo_sapiens	ENSP00000415885	76.6566	63.7048	latimeria_chalumnae	ENSLACP00000009969	76.6566	63.7048
ENSG00000137760	homo_sapiens	ENSP00000415885	74.5482	59.0361	lepisosteus_oculatus	ENSLOCP00000008266	72.2628	57.2263
ENSG00000137760	homo_sapiens	ENSP00000415885	70.6325	56.3253	clupea_harengus	ENSCHAP00000041182	71.1684	56.7527
ENSG00000137760	homo_sapiens	ENSP00000415885	71.8373	56.6265	danio_rerio	ENSDARP00000079150	71.6216	56.4565
ENSG00000137760	homo_sapiens	ENSP00000415885	72.5904	57.0783	carassius_auratus	ENSCARP00000057320	73.2523	57.5988
ENSG00000137760	homo_sapiens	ENSP00000415885	71.0843	56.3253	astyanax_mexicanus	ENSAMXP00000049864	73.2919	58.0745
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	54.9699	ictalurus_punctatus	ENSIPUP00000013879	71.2557	55.2194
ENSG00000137760	homo_sapiens	ENSP00000415885	70.4819	56.9277	esox_lucius	ENSELUP00000011868	62.234	50.266
ENSG00000137760	homo_sapiens	ENSP00000415885	69.7289	56.1747	electrophorus_electricus	ENSEEEP00000023850	72.3438	58.2812
ENSG00000137760	homo_sapiens	ENSP00000415885	70.6325	56.4759	oncorhynchus_kisutch	ENSOKIP00005034644	64.5117	51.5818
ENSG00000137760	homo_sapiens	ENSP00000415885	71.2349	56.7771	oncorhynchus_mykiss	ENSOMYP00000107047	64.8834	51.7147
ENSG00000137760	homo_sapiens	ENSP00000415885	70.7831	56.3253	salmo_salar	ENSSSAP00000173632	60.7235	48.3204
ENSG00000137760	homo_sapiens	ENSP00000415885	70.7831	56.4759	salmo_trutta	ENSSTUP00000025681	63.5135	50.6757
ENSG00000137760	homo_sapiens	ENSP00000415885	70.3313	53.4639	gadus_morhua	ENSGMOP00000032892	60.8073	46.224
ENSG00000137760	homo_sapiens	ENSP00000415885	70.0301	53.7651	fundulus_heteroclitus	ENSFHEP00000002870	67.0996	51.5152
ENSG00000137760	homo_sapiens	ENSP00000415885	61.747	46.988	poecilia_reticulata	ENSPREP00000030976	67.8808	51.6556
ENSG00000137760	homo_sapiens	ENSP00000415885	71.2349	54.8193	xiphophorus_maculatus	ENSXMAP00000010906	69.2533	53.2943
ENSG00000137760	homo_sapiens	ENSP00000415885	69.7289	53.7651	oryzias_latipes	ENSORLP00000013082	71.4506	55.0926
ENSG00000137760	homo_sapiens	ENSP00000415885	61.4458	46.8373	cyclopterus_lumpus	ENSCLMP00005013317	66.9951	51.0673
ENSG00000137760	homo_sapiens	ENSP00000415885	69.7289	54.5181	oreochromis_niloticus	ENSONIP00000050511	62.4831	48.8529
ENSG00000137760	homo_sapiens	ENSP00000415885	70.1807	55.2711	haplochromis_burtoni	ENSHBUP00000010368	63.4014	49.932
ENSG00000137760	homo_sapiens	ENSP00000415885	70.0301	55.1205	astatotilapia_calliptera	ENSACLP00000033619	63.2653	49.7959
ENSG00000137760	homo_sapiens	ENSP00000415885	71.8373	55.5723	sparus_aurata	ENSSAUP00010000262	65.075	50.3411
ENSG00000137760	homo_sapiens	ENSP00000415885	71.0843	55.5723	lates_calcarifer	ENSLCAP00010001315	67.0455	52.4148
ENSG00000137760	homo_sapiens	ENSP00000415885	70.6325	57.9819	xenopus_tropicalis	ENSXETP00000031718	78.2972	64.2738
ENSG00000137760	homo_sapiens	ENSP00000415885	85.8434	71.3855	chrysemys_picta_bellii	ENSCPBP00000026224	80.5085	66.9492
ENSG00000137760	homo_sapiens	ENSP00000415885	77.259	68.0723	sphenodon_punctatus	ENSSPUP00000019734	79.0447	69.6456
ENSG00000137760	homo_sapiens	ENSP00000415885	56.3253	47.5904	crocodylus_porosus	ENSCPRP00005020685	82.7434	69.9115
ENSG00000137760	homo_sapiens	ENSP00000415885	28.3133	22.4398	crocodylus_porosus	ENSCPRP00005020680	75.502	59.8394
ENSG00000137760	homo_sapiens	ENSP00000415885	24.5482	19.4277	laticauda_laticaudata	ENSLLTP00000021157	69.6581	55.1282
ENSG00000137760	homo_sapiens	ENSP00000415885	25.753	20.6325	notechis_scutatus	ENSNSUP00000022850	68.1275	54.5817
ENSG00000137760	homo_sapiens	ENSP00000415885	77.4096	63.1024	pseudonaja_textilis	ENSPTXP00000023621	77.5264	63.1976
ENSG00000137760	homo_sapiens	ENSP00000415885	82.6807	67.6205	anas_platyrhynchos_platyrhynchos	ENSAPLP00000019671	66.7072	54.5565
ENSG00000137760	homo_sapiens	ENSP00000415885	81.4759	67.1687	gallus_gallus	ENSGALP00010006256	74.8271	61.6874
ENSG00000137760	homo_sapiens	ENSP00000415885	28.4639	23.1928	meleagris_gallopavo	ENSMGAP00000016072	75.6	61.6
ENSG00000137760	homo_sapiens	ENSP00000415885	82.0783	67.3193	serinus_canaria	ENSSCAP00000005654	80.8605	66.3205
ENSG00000137760	homo_sapiens	ENSP00000415885	81.6265	67.3193	parus_major	ENSPMJP00000024214	80.5349	66.419
ENSG00000137760	homo_sapiens	ENSP00000415885	79.9699	65.2108	anolis_carolinensis	ENSACAP00000010712	79.7297	65.015
ENSG00000137760	homo_sapiens	ENSP00000415885	67.6205	53.1627	neolamprologus_brichardi	ENSNBRP00000018311	71.0443	55.8544
ENSG00000137760	homo_sapiens	ENSP00000415885	25.1506	19.5783	naja_naja	ENSNNAP00000013105	71.0638	55.3191
ENSG00000137760	homo_sapiens	ENSP00000415885	79.6687	66.8675	podarcis_muralis	ENSPMRP00000000354	80.5175	67.5799
ENSG00000137760	homo_sapiens	ENSP00000415885	81.7771	67.1687	geospiza_fortis	ENSGFOP00000011511	80.5638	66.1721
ENSG00000137760	homo_sapiens	ENSP00000415885	82.3795	68.5241	taeniopygia_guttata	ENSTGUP00000025733	70.7633	58.8616
ENSG00000137760	homo_sapiens	ENSP00000415885	73.3434	57.9819	erpetoichthys_calabaricus	ENSECRP00000003813	75.387	59.5975
ENSG00000137760	homo_sapiens	ENSP00000415885	70.3313	55.1205	kryptolebias_marmoratus	ENSKMAP00000011258	67.3882	52.8139
ENSG00000137760	homo_sapiens	ENSP00000415885	76.9578	64.6084	salvator_merianae	ENSSMRP00000014134	76.0417	63.8393
ENSG00000137760	homo_sapiens	ENSP00000415885	70.0301	54.9699	oryzias_javanicus	ENSOJAP00000032403	67.3913	52.8986
ENSG00000137760	homo_sapiens	ENSP00000415885	68.3735	53.9157	amphilophus_citrinellus	ENSACIP00000004561	67.7612	53.4328
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	54.6687	dicentrarchus_labrax	ENSDLAP00005045962	63.7348	49.1204
ENSG00000137760	homo_sapiens	ENSP00000415885	69.4277	54.3675	amphiprion_percula	ENSAPEP00000022878	61.8792	48.4564
ENSG00000137760	homo_sapiens	ENSP00000415885	67.0181	52.7108	oryzias_sinensis	ENSOSIP00000041798	67.0181	52.7108
ENSG00000137760	homo_sapiens	ENSP00000415885	71.5361	59.7892	pelodiscus_sinensis	ENSPSIP00000012918	74.103	61.9345
ENSG00000137760	homo_sapiens	ENSP00000415885	84.7892	71.5361	gopherus_evgoodei	ENSGEVP00005017281	83.7798	70.6845
ENSG00000137760	homo_sapiens	ENSP00000415885	28.6145	23.7952	chelonoidis_abingdonii	ENSCABP00000027395	78.1893	65.0206
ENSG00000137760	homo_sapiens	ENSP00000415885	70.6325	55.7229	seriola_dumerili	ENSSDUP00000002066	62.4501	49.2676
ENSG00000137760	homo_sapiens	ENSP00000415885	70.3313	53.7651	cottoperca_gobio	ENSCGOP00000008342	62.3498	47.6636
ENSG00000137760	homo_sapiens	ENSP00000415885	68.6747	53.1627	gasterosteus_aculeatus	ENSGACP00000010829	69.1957	53.566
ENSG00000137760	homo_sapiens	ENSP00000415885	69.8795	55.2711	cynoglossus_semilaevis	ENSCSEP00000028913	64.0884	50.6906
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	54.3675	poecilia_formosa	ENSPFOP00000001565	68.9605	52.8551
ENSG00000137760	homo_sapiens	ENSP00000415885	71.6867	56.1747	myripristis_murdjan	ENSMMDP00005045557	62.6316	49.0789
ENSG00000137760	homo_sapiens	ENSP00000415885	69.5783	53.012	sander_lucioperca	ENSSLUP00000026136	62.1804	47.3755
ENSG00000137760	homo_sapiens	ENSP00000415885	81.7771	67.3193	strigops_habroptila	ENSSHBP00005000456	79.5022	65.4466
ENSG00000137760	homo_sapiens	ENSP00000415885	70.3313	54.5181	amphiprion_ocellaris	ENSAOCP00000013109	62.6846	48.5906
ENSG00000137760	homo_sapiens	ENSP00000415885	84.6386	71.5361	terrapene_carolina_triunguis	ENSTMTP00000013728	83.631	70.6845
ENSG00000137760	homo_sapiens	ENSP00000415885	12.1988	9.63855	hucho_hucho	ENSHHUP00000012789	64.8	51.2
ENSG00000137760	homo_sapiens	ENSP00000415885	71.2349	56.9277	hucho_hucho	ENSHHUP00000035560	68.75	54.9419
ENSG00000137760	homo_sapiens	ENSP00000415885	69.8795	54.3675	betta_splendens	ENSBSLP00000027011	64.8045	50.419
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	56.4759	pygocentrus_nattereri	ENSPNAP00000014933	72.0183	57.3395
ENSG00000137760	homo_sapiens	ENSP00000415885	71.8373	55.2711	anabas_testudineus	ENSATEP00000011704	65.522	50.4121
ENSG00000137760	homo_sapiens	ENSP00000415885	54.9699	37.0482	ciona_savignyi	ENSCSAVP00000001133	62.3932	42.0513
ENSG00000137760	homo_sapiens	ENSP00000415885	23.6446	15.6627	saccharomyces_cerevisiae	YML014W	56.2724	37.276
ENSG00000137760	homo_sapiens	ENSP00000415885	68.8253	54.6687	seriola_lalandi_dorsalis	ENSSLDP00000002679	69.4529	55.1672
ENSG00000137760	homo_sapiens	ENSP00000415885	71.6867	54.5181	labrus_bergylta	ENSLBEP00000025073	67.2316	51.1299
ENSG00000137760	homo_sapiens	ENSP00000415885	68.3735	53.7651	pundamilia_nyererei	ENSPNYP00000019971	71.3836	56.1321
ENSG00000137760	homo_sapiens	ENSP00000415885	71.2349	55.4217	mastacembelus_armatus	ENSMAMP00000010543	63.4899	49.396
ENSG00000137760	homo_sapiens	ENSP00000415885	70.6325	54.6687	stegastes_partitus	ENSSPAP00000016498	63.2928	48.9879
ENSG00000137760	homo_sapiens	ENSP00000415885	48.494	38.5542	oncorhynchus_tshawytscha	ENSOTSP00005010085	72.5225	57.6577
ENSG00000137760	homo_sapiens	ENSP00000415885	70.0301	54.6687	acanthochromis_polyacanthus	ENSAPOP00000000374	62.9229	49.1204
ENSG00000137760	homo_sapiens	ENSP00000415885	82.8313	68.2229	aquila_chrysaetos_chrysaetos	ENSACCP00020011267	80.5271	66.325
ENSG00000137760	homo_sapiens	ENSP00000415885	69.4277	54.6687	nothobranchius_furzeri	ENSNFUP00015004592	67.2012	52.9155
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	55.2711	cyprinodon_variegatus	ENSCVAP00000023539	68.6589	53.4985
ENSG00000137760	homo_sapiens	ENSP00000415885	69.8795	55.8735	denticeps_clupeoides	ENSDCDP00000050651	72.3869	57.8783
ENSG00000137760	homo_sapiens	ENSP00000415885	71.0843	54.3675	larimichthys_crocea	ENSLCRP00005048111	63.7838	48.7838
ENSG00000137760	homo_sapiens	ENSP00000415885	69.4277	52.8614	takifugu_rubripes	ENSTRUP00000017151	65.113	49.5763
ENSG00000137760	homo_sapiens	ENSP00000415885	82.0783	67.6205	ficedula_albicollis	ENSFALP00000018631	80.8605	66.6172
ENSG00000137760	homo_sapiens	ENSP00000415885	70.1807	52.8614	hippocampus_comes	ENSHCOP00000012394	71.145	53.5878
ENSG00000137760	homo_sapiens	ENSP00000415885	72.741	57.3795	cyprinus_carpio_carpio	ENSCCRP00000096025	70.1016	55.2975
ENSG00000137760	homo_sapiens	ENSP00000415885	82.0783	68.2229	coturnix_japonica	ENSCJPP00005003252	79.562	66.1314
ENSG00000137760	homo_sapiens	ENSP00000415885	70.9337	54.6687	poecilia_latipinna	ENSPLAP00000023296	68.9605	53.1479
ENSG00000137760	homo_sapiens	ENSP00000415885	72.1386	56.6265	sinocyclocheilus_grahami	ENSSGRP00000033388	69.3198	54.4139
ENSG00000137760	homo_sapiens	ENSP00000415885	18.5241	13.7048	sinocyclocheilus_grahami	ENSSGRP00000012091	60.2941	44.6078
ENSG00000137760	homo_sapiens	ENSP00000415885	70.0301	55.1205	maylandia_zebra	ENSMZEP00005018835	63.2653	49.7959
ENSG00000137760	homo_sapiens	ENSP00000415885	13.8554	11.1446	tetraodon_nigroviridis	ENSTNIP00000013188	85.1852	68.5185
ENSG00000137760	homo_sapiens	ENSP00000415885	68.0723	51.9578	tetraodon_nigroviridis	ENSTNIP00000013189	70.2955	53.6547
ENSG00000137760	homo_sapiens	ENSP00000415885	69.7289	56.3253	paramormyrops_kingsleyae	ENSPKIP00000008016	68.7964	55.5721
ENSG00000137760	homo_sapiens	ENSP00000415885	72.4398	56.6265	scleropages_formosus	ENSSFOP00015004830	73.2116	57.2298
ENSG00000137760	homo_sapiens	ENSP00000415885	74.247	59.9398	leptobrachium_leishanense	ENSLLEP00000030723	76.4341	61.7054
ENSG00000137760	homo_sapiens	ENSP00000415885	61.747	48.1928	scophthalmus_maximus	ENSSMAP00000046085	63.3694	49.459
ENSG00000137760	homo_sapiens	ENSP00000415885	69.4277	54.8193	oryzias_melastigma	ENSOMEP00000022696	66.7149	52.6773

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000049	enables tRNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0002098	involved_in tRNA wobble uridine modification	3	IBA,IDA,IMP	Homo_sapiens(9606)	Process
GO:0005506	enables iron ion binding	1	ISS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0006974	involved_in DNA damage response	1	IDA	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IDA	Homo_sapiens(9606)	Function
GO:0016300	enables tRNA (uracil) methyltransferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0016706	enables 2-oxoglutarate-dependent dioxygenase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0030488	involved_in tRNA methylation	3	IBA,IDA,IMP	Homo_sapiens(9606)	Process
GO:0106335	enables tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	1	IBA	Homo_sapiens(9606)	Function