RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000137547	Gene ID	29088	Accession	14054
Symbol	MRPL15	Alias	L15mt;RPML7;uL15m;MRP-L7;HSPC145;MRP-L15	Full Name	mitochondrial ribosomal protein L15
Status	Confidence	Length	13274 bases	Strand	Plus strand
Position	8 : 54135241 - 54148514	RNA binding domain	Ribosomal_L27A
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]