Ensembl ID
ENSG00000137547
Gene ID
29088
Accession
14054
Gene Symbol
MRPL15
Alias
L15mt;RPML7;uL15m;MRP-L7;HSPC145;MRP-L15
Full Name
mitochondrial ribosomal protein L15
Position
8 : 54135241 - 54148514
Length
13274 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs rRNA RBP type
Canonical_RBPs
Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]
ENSG00000137547 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000137547
MRPL15
0.82
7.75e-26
BRCA
ENSG00000137547
MRPL15
1.04
2.28e-20
KICH
ENSG00000137547
MRPL15
1.14
2.55e-30
LUSC
ENSG00000137547
MRPL15
0.54
3.79e-11
PRAD
ENSG00000137547
MRPL15
1.15
2.93e-27
UCEC
ENSG00000137547
MRPL15
1.11
7.85e-26
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000137547
MRPL15
MESO
0.017
low
show
ENSG00000137547
MRPL15
SARC
0.00049
high
show
ENSG00000137547
MRPL15
PAAD
0.0028
high
show
ENSG00000137547
MRPL15
UCEC
0.00022
high
show
ENSG00000137547
MRPL15
LGG
0.0049
high
show
ENSG00000137547
MRPL15
HNSC
0.023
high
show
ENSG00000137547
MRPL15
LUAD
0.00062
high
show
ENSG00000137547
MRPL15
PCPG
0.0068
high
show
ENSG00000137547
MRPL15
BRCA
0.0048
high
show
ENSG00000137547
MRPL15
UCS
0.044
high
show
ENSG00000137547
MRPL15
ESCA
0.031
high
show
ENSG00000137547
MRPL15
OV
0.014
low
show
ENSG00000137547
MRPL15
KIRC
0.038
high
show
ENSG00000137547
MRPL15
PRAD
0.0086
high
show
ENSG00000137547
MRPL15
BLCA
0.0022
low
show
ENSG00000137547
MRPL15
LAML
0.015
high
show
ENSG00000137547
MRPL15
SKCM
0.031
high
show
ENSG00000137547
MRPL15
LIHC
0.01
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000137547
MRPL15
LUAD
Amp
0.919182
0.123066
0.577277
0.465116
ENSG00000137547
MRPL15
READ
Amp
1.025278
0.142025
0.757655
0.569697
ENSG00000137547
MRPL15
COAD
Amp
0.615830
0.065499
0.721371
0.501109
ENSG00000137547
MRPL15
UCS
Amp
4.344696
1.000093
1.276397
0.678571
ENSG00000137547
MRPL15
TGCT
Amp
3.657681
0.242131
0.586994
0.813333
ENSG00000137547
MRPL15
BRCA
Amp
1.246086
0.156625
0.864324
0.495370
ENSG00000137547
MRPL15
PRAD
Amp
1.071089
0.051118
0.670411
0.243902
ENSG00000137547
MRPL15
UCEC
Amp
2.378826
0.140397
0.778112
0.341373
ENSG00000137547
MRPL15
UVM
Amp
3.526633
0.325223
1.517112
0.600000
ENSG00000137547
MRPL15
OV
Amp
6.972906
0.491362
0.839280
0.519862
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