Ensembl ID ENSG00000137547 Gene ID 29088 Accession 14054
Gene Symbol MRPL15 Alias L15mt;RPML7;uL15m;MRP-L7;HSPC145;MRP-L15 Full Name mitochondrial ribosomal protein L15
Position 8 : 54135241 - 54148514 Length 13274 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]

ENSG00000137547 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000137547 MRPL15 0.82 7.75e-26 BRCA
ENSG00000137547 MRPL15 1.04 2.28e-20 KICH
ENSG00000137547 MRPL15 1.14 2.55e-30 LUSC
ENSG00000137547 MRPL15 0.54 3.79e-11 PRAD
ENSG00000137547 MRPL15 1.15 2.93e-27 UCEC
ENSG00000137547 MRPL15 1.11 7.85e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000137547 MRPL15 MESO 0.017 low
ENSG00000137547 MRPL15 SARC 0.00049 high
ENSG00000137547 MRPL15 PAAD 0.0028 high
ENSG00000137547 MRPL15 UCEC 0.00022 high
ENSG00000137547 MRPL15 LGG 0.0049 high
ENSG00000137547 MRPL15 HNSC 0.023 high
ENSG00000137547 MRPL15 LUAD 0.00062 high
ENSG00000137547 MRPL15 PCPG 0.0068 high
ENSG00000137547 MRPL15 BRCA 0.0048 high
ENSG00000137547 MRPL15 UCS 0.044 high
ENSG00000137547 MRPL15 ESCA 0.031 high
ENSG00000137547 MRPL15 OV 0.014 low
ENSG00000137547 MRPL15 KIRC 0.038 high
ENSG00000137547 MRPL15 PRAD 0.0086 high
ENSG00000137547 MRPL15 BLCA 0.0022 low
ENSG00000137547 MRPL15 LAML 0.015 high
ENSG00000137547 MRPL15 SKCM 0.031 high
ENSG00000137547 MRPL15 LIHC 0.01 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000137547 MRPL15 LUAD Amp 0.919182 0.123066 0.577277 0.465116
ENSG00000137547 MRPL15 READ Amp 1.025278 0.142025 0.757655 0.569697
ENSG00000137547 MRPL15 COAD Amp 0.615830 0.065499 0.721371 0.501109
ENSG00000137547 MRPL15 UCS Amp 4.344696 1.000093 1.276397 0.678571
ENSG00000137547 MRPL15 TGCT Amp 3.657681 0.242131 0.586994 0.813333
ENSG00000137547 MRPL15 BRCA Amp 1.246086 0.156625 0.864324 0.495370
ENSG00000137547 MRPL15 PRAD Amp 1.071089 0.051118 0.670411 0.243902
ENSG00000137547 MRPL15 UCEC Amp 2.378826 0.140397 0.778112 0.341373
ENSG00000137547 MRPL15 UVM Amp 3.526633 0.325223 1.517112 0.600000
ENSG00000137547 MRPL15 OV Amp 6.972906 0.491362 0.839280 0.519862