RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
diverse
Moonlighting functions
N.A.
Localizations
Nucleoli
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000137074 Gene ID
54840 Accession
15984
Symbol
APTX
Alias
AOA;AOA1;AXA1;EAOH;EOAHA;FHA-HIT
Full Name
aprataxin
Status
Confidence
Length
138530 bases
Strand
Minus strand
Position
9 : 32886601 - 33025130
RNA binding domain
DcpS_C
Summary
This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000499997
DcpS_C
PF11969 2e-33
1
ENSP00000500601
DcpS_C
PF11969 2e-33
1
ENSP00000500738
DcpS_C
PF11969 2e-33
1
ENSP00000380357
DcpS_C
PF11969 2.1e-33
1
ENSP00000369153
DcpS_C
PF11969 2.4e-33
1
ENSP00000420263
DcpS_C
PF11969 2.4e-33
1
ENSP00000311547
DcpS_C
PF11969 2.7e-33
1
ENSP00000400806
DcpS_C
PF11969 2.7e-33
1
ENSP00000419042
DcpS_C
PF11969 2.7e-33
1
ENSP00000417649
DcpS_C
PF11969 2.9e-33
1
ENSP00000369145
DcpS_C
PF11969 3.2e-33
1
ENSP00000369147
DcpS_C
PF11969 3.2e-33
1
ENSP00000419846
DcpS_C
PF11969 3.2e-33
1
ENSP00000499991
DcpS_C
PF11969 6.1e-33
1
ENSP00000369141
DcpS_C
PF11969 1.5e-32
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
24362567 Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity.
Percy Tumbale
2014-02-06
Nature
25637650 Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease.
J Matthew Schellenberg
2015-03-01
Progress in biophysics and molecular biology
24794402 Ribonucleotides in DNA: origins, repair and consequences.
S Jessica Williams
2014-07-01
DNA repair
21246735 To live or to die: a matter of processing damaged DNA termini in neurons.
F Sherif El-Khamisy
2011-02-01
EMBO molecular medicine
Name
Transcript ID
bp
Protein
Translation ID
APTX-245
ENST00000672846
1897
49aa
ENSP00000500396
APTX-241
ENST00000672519
4256
49aa
ENSP00000500320
APTX-235
ENST00000672244
2728
138aa
ENSP00000499875
APTX-253
ENST00000673416
3202
254aa
ENSP00000500738
APTX-252
ENST00000673360
2966
68aa
ENSP00000500360
APTX-205
ENST00000379825
2023
292aa
ENSP00000369153
APTX-228
ENST00000494649
2099
49aa
ENSP00000417634
APTX-206
ENST00000397172
1740
270aa
ENSP00000380357
APTX-203
ENST00000379817
1977
342aa
ENSP00000369145
APTX-249
ENST00000673211
1991
No protein
-
APTX-244
ENST00000672615
1986
No protein
-
APTX-254
ENST00000673485
2106
No protein
-
APTX-239
ENST00000672476
2101
No protein
-
APTX-247
ENST00000673171
1759
No protein
-
APTX-234
ENST00000672152
1879
No protein
-
APTX-207
ENST00000436040
1846
288aa
ENSP00000400806
APTX-212
ENST00000465003
1914
49aa
ENSP00000419430
APTX-215
ENST00000472896
1962
52aa
ENSP00000417804
APTX-221
ENST00000479656
2057
49aa
ENSP00000420071
APTX-251
ENST00000673333
2178
No protein
-
APTX-213
ENST00000467331
1938
49aa
ENSP00000418733
APTX-255
ENST00000673487
2101
49aa
ENSP00000500943
APTX-224
ENST00000483148
2022
85aa
ENSP00000419723
APTX-223
ENST00000482687
1822
49aa
ENSP00000419289
APTX-238
ENST00000672438
1805
254aa
ENSP00000499997
APTX-225
ENST00000485479
1814
49aa
ENSP00000418144
APTX-256
ENST00000673598
1394
168aa
ENSP00000499991
APTX-208
ENST00000460940
1725
49aa
ENSP00000418311
APTX-201
ENST00000309615
1742
288aa
ENSP00000311547
APTX-204
ENST00000379819
1938
342aa
ENSP00000369147
APTX-237
ENST00000672286
2032
No protein
-
APTX-240
ENST00000672493
3108
No protein
-
APTX-250
ENST00000673248
1880
254aa
ENSP00000500601
APTX-232
ENST00000671774
1782
No protein
-
APTX-217
ENST00000474658
952
68aa
ENSP00000417750
APTX-210
ENST00000463596
1345
342aa
ENSP00000419846
APTX-242
ENST00000672535
1861
49aa
ENSP00000499872
APTX-218
ENST00000476858
1068
288aa
ENSP00000419042
APTX-236
ENST00000672281
1348
No protein
-
APTX-230
ENST00000495360
1184
60aa
ENSP00000419623
APTX-214
ENST00000468275
1213
292aa
ENSP00000420263
APTX-248
ENST00000673181
1657
No protein
-
APTX-219
ENST00000477119
1031
303aa
ENSP00000417649
APTX-233
ENST00000671912
650
104aa
ENSP00000500871
APTX-226
ENST00000486724
556
No protein
-
APTX-246
ENST00000673114
2284
No protein
-
APTX-211
ENST00000464632
679
49aa
ENSP00000418069
APTX-220
ENST00000478279
684
85aa
ENSP00000419597
APTX-222
ENST00000480031
672
52aa
ENSP00000417684
APTX-231
ENST00000496030
1458
No protein
-
APTX-209
ENST00000460945
1152
No protein
-
APTX-229
ENST00000494973
547
No protein
-
APTX-243
ENST00000672553
1214
No protein
-
APTX-216
ENST00000473270
645
No protein
-
APTX-227
ENST00000489583
397
No protein
-
APTX-202
ENST00000379813
1121
336aa
ENSP00000369141
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
14056 Pancreatic Neoplasms 1.3410000E-004 19648918
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000137074 homo_sapiens ENSP00000229633 45.6044 21.978 homo_sapiens ENSP00000369145 24.269 11.6959
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000137074 homo_sapiens ENSP00000369145 99.1228 98.2456 nomascus_leucogenys ENSNLEP00000049274 95.7627 94.9153 ENSG00000137074 homo_sapiens ENSP00000369145 99.7076 99.4152 pan_paniscus ENSPPAP00000014316 96.3277 96.0452 ENSG00000137074 homo_sapiens ENSP00000369145 98.538 98.538 pongo_abelii ENSPPYP00000027254 94.6629 94.6629 ENSG00000137074 homo_sapiens ENSP00000369145 99.7076 99.4152 pan_troglodytes ENSPTRP00000082797 96.3277 96.0452 ENSG00000137074 homo_sapiens ENSP00000369145 85.6725 84.7953 gorilla_gorilla ENSGGOP00000049163 88.7879 87.8788 ENSG00000137074 homo_sapiens ENSP00000369145 71.9298 60.2339 ornithorhynchus_anatinus ENSOANP00000049271 76.3975 63.9752 ENSG00000137074 homo_sapiens ENSP00000369145 46.4912 29.5322 ornithorhynchus_anatinus ENSOANP00000032651 24.3119 15.4434 ENSG00000137074 homo_sapiens ENSP00000369145 81.5789 68.7134 sarcophilus_harrisii ENSSHAP00000030424 79.4872 66.9516 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 64.9123 notamacropus_eugenii ENSMEUP00000003785 76.6082 64.9123 ENSG00000137074 homo_sapiens ENSP00000369145 67.5439 62.8655 choloepus_hoffmanni ENSCHOP00000002224 64.3454 59.8886 ENSG00000137074 homo_sapiens ENSP00000369145 94.152 89.4737 dasypus_novemcinctus ENSDNOP00000014363 90.4494 85.9551 ENSG00000137074 homo_sapiens ENSP00000369145 77.4854 73.0994 erinaceus_europaeus ENSEEUP00000009739 86.6013 81.6993 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 70.7602 echinops_telfairi ENSETEP00000010101 71.831 68.169 ENSG00000137074 homo_sapiens ENSP00000369145 96.4912 93.5673 callithrix_jacchus ENSCJAP00000083546 96.2099 93.2945 ENSG00000137074 homo_sapiens ENSP00000369145 97.6608 96.7836 cercocebus_atys ENSCATP00000040184 90.7609 89.9457 ENSG00000137074 homo_sapiens ENSP00000369145 97.9532 97.3684 macaca_fascicularis ENSMFAP00000048558 91.0326 90.4891 ENSG00000137074 homo_sapiens ENSP00000369145 98.2456 97.6608 macaca_mulatta ENSMMUP00000010149 94.382 93.8202 ENSG00000137074 homo_sapiens ENSP00000369145 97.9532 97.076 macaca_nemestrina ENSMNEP00000038714 97.9532 97.076 ENSG00000137074 homo_sapiens ENSP00000369145 92.6901 91.8129 papio_anubis ENSPANP00000039702 94.3452 93.4524 ENSG00000137074 homo_sapiens ENSP00000369145 98.2456 97.076 mandrillus_leucophaeus ENSMLEP00000022053 94.382 93.2584 ENSG00000137074 homo_sapiens ENSP00000369145 84.2105 79.2398 tursiops_truncatus ENSTTRP00000006988 87.538 82.3708 ENSG00000137074 homo_sapiens ENSP00000369145 88.0117 81.5789 vulpes_vulpes ENSVVUP00000028900 80.4813 74.5989 ENSG00000137074 homo_sapiens ENSP00000369145 89.7661 85.0877 mus_spretus MGP_SPRETEiJ_P0064224 88.9855 84.3478 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.0585 equus_asinus ENSEASP00005044130 87.2973 83.2432 ENSG00000137074 homo_sapiens ENSP00000369145 90.0585 85.0877 capra_hircus ENSCHIP00000010424 83.6957 79.0761 ENSG00000137074 homo_sapiens ENSP00000369145 95.0292 91.5205 loxodonta_africana ENSLAFP00000004754 94.4767 90.9884 ENSG00000137074 homo_sapiens ENSP00000369145 96.1988 92.1053 panthera_leo ENSPLOP00000025720 96.1988 92.1053 ENSG00000137074 homo_sapiens ENSP00000369145 89.4737 84.7953 ailuropoda_melanoleuca ENSAMEP00000008089 87.6791 83.0946 ENSG00000137074 homo_sapiens ENSP00000369145 93.8596 89.1813 bos_indicus_hybrid ENSBIXP00005019470 92.5072 87.8963 ENSG00000137074 homo_sapiens ENSP00000369145 92.3977 90.0585 oryctolagus_cuniculus ENSOCUP00000000638 92.6686 90.3226 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.3509 equus_caballus ENSECAP00000034186 94.4444 90.3509 ENSG00000137074 homo_sapiens ENSP00000369145 96.7836 92.1053 canis_lupus_familiaris ENSCAFP00845027330 96.7836 92.1053 ENSG00000137074 homo_sapiens ENSP00000369145 96.1988 92.1053 panthera_pardus ENSPPRP00000026442 96.1988 92.1053 ENSG00000137074 homo_sapiens ENSP00000369145 77.4854 72.2222 marmota_marmota_marmota ENSMMMP00000009904 93.3099 86.9718 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.0585 balaenoptera_musculus ENSBMSP00010002521 93.0836 88.7608 ENSG00000137074 homo_sapiens ENSP00000369145 93.5673 89.1813 cavia_porcellus ENSCPOP00000029271 93.8416 89.4428 ENSG00000137074 homo_sapiens ENSP00000369145 88.5965 83.0409 felis_catus ENSFCAP00000056077 81.6712 76.5499 ENSG00000137074 homo_sapiens ENSP00000369145 95.0292 90.6433 ursus_americanus ENSUAMP00000004036 92.8571 88.5714 ENSG00000137074 homo_sapiens ENSP00000369145 78.3626 63.7427 monodelphis_domestica ENSMODP00000004116 72.8261 59.2391 ENSG00000137074 homo_sapiens ENSP00000369145 93.8596 89.4737 bison_bison_bison ENSBBBP00000002189 90.4225 86.1972 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.3509 monodon_monoceros ENSMMNP00015027337 88.2514 84.4262 ENSG00000137074 homo_sapiens ENSP00000369145 95.3216 90.6433 sus_scrofa ENSSSCP00000053859 91.573 87.0787 ENSG00000137074 homo_sapiens ENSP00000369145 96.1988 92.3977 microcebus_murinus ENSMICP00000019890 92.4157 88.764 ENSG00000137074 homo_sapiens ENSP00000369145 73.3918 70.1754 octodon_degus ENSODEP00000000107 91.9414 87.9121 ENSG00000137074 homo_sapiens ENSP00000369145 93.2749 88.8889 octodon_degus ENSODEP00000021508 90.625 86.3636 ENSG00000137074 homo_sapiens ENSP00000369145 88.5965 82.1637 jaculus_jaculus ENSJJAP00000012691 93.2308 86.4615 ENSG00000137074 homo_sapiens ENSP00000369145 93.5673 89.1813 ovis_aries_rambouillet ENSOARP00020014277 90.1408 85.9155 ENSG00000137074 homo_sapiens ENSP00000369145 95.0292 90.6433 ursus_maritimus ENSUMAP00000007547 88.0759 84.0108 ENSG00000137074 homo_sapiens ENSP00000369145 75.4386 71.9298 ochotona_princeps ENSOPRP00000011317 84.8684 80.9211 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.3509 delphinapterus_leucas ENSDLEP00000029183 77.458 74.1007 ENSG00000137074 homo_sapiens ENSP00000369145 94.152 88.8889 physeter_catodon ENSPCTP00005002314 90.4494 85.3933 ENSG00000137074 homo_sapiens ENSP00000369145 66.3743 64.0351 mus_caroli MGP_CAROLIEiJ_P0061790 91.1647 87.9518 ENSG00000137074 homo_sapiens ENSP00000369145 89.1813 84.7953 mus_musculus ENSMUSP00000124264 89.1813 84.7953 ENSG00000137074 homo_sapiens ENSP00000369145 89.1813 85.0877 dipodomys_ordii ENSDORP00000024462 88.6628 84.593 ENSG00000137074 homo_sapiens ENSP00000369145 95.3216 89.7661 mustela_putorius_furo ENSMPUP00000004256 95.3216 89.7661 ENSG00000137074 homo_sapiens ENSP00000369145 97.076 94.7368 aotus_nancymaae ENSANAP00000024978 93.2584 91.0112 ENSG00000137074 homo_sapiens ENSP00000369145 96.7836 94.4444 saimiri_boliviensis_boliviensis ENSSBOP00000017168 96.5015 94.1691 ENSG00000137074 homo_sapiens ENSP00000369145 64.6199 62.2807 vicugna_pacos ENSVPAP00000001196 64.4315 62.0991 ENSG00000137074 homo_sapiens ENSP00000369145 98.538 97.9532 chlorocebus_sabaeus ENSCSAP00000006126 94.6629 94.1011 ENSG00000137074 homo_sapiens ENSP00000369145 88.0117 83.6257 tupaia_belangeri ENSTBEP00000007365 84.5506 80.3371 ENSG00000137074 homo_sapiens ENSP00000369145 89.4737 84.5029 mesocricetus_auratus ENSMAUP00000004598 90 85 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.3509 phocoena_sinus ENSPSNP00000003102 88.2514 84.4262 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 89.1813 camelus_dromedarius ENSCDRP00005009038 94.4444 89.1813 ENSG00000137074 homo_sapiens ENSP00000369145 93.8596 90.6433 carlito_syrichta ENSTSYP00000032495 93.8596 90.6433 ENSG00000137074 homo_sapiens ENSP00000369145 96.1988 92.1053 panthera_tigris_altaica ENSPTIP00000023686 96.1988 92.1053 ENSG00000137074 homo_sapiens ENSP00000369145 85.9649 80.7018 rattus_norvegicus ENSRNOP00000094475 85.7143 80.4665 ENSG00000137074 homo_sapiens ENSP00000369145 52.924 51.1696 prolemur_simus ENSPSMP00000007698 96.7914 93.5829 ENSG00000137074 homo_sapiens ENSP00000369145 97.076 93.8596 prolemur_simus ENSPSMP00000025233 91.9668 88.9197 ENSG00000137074 homo_sapiens ENSP00000369145 89.7661 83.9181 microtus_ochrogaster ENSMOCP00000001136 89.7661 83.9181 ENSG00000137074 homo_sapiens ENSP00000369145 91.8129 87.1345 peromyscus_maniculatus_bairdii ENSPEMP00000005317 92.3529 87.6471 ENSG00000137074 homo_sapiens ENSP00000369145 93.8596 89.1813 bos_mutus ENSBMUP00000022843 93.8596 89.1813 ENSG00000137074 homo_sapiens ENSP00000369145 81.5789 75.4386 mus_spicilegus ENSMSIP00000008104 76.0218 70.2997 ENSG00000137074 homo_sapiens ENSP00000369145 88.8889 84.5029 cricetulus_griseus_chok1gshd ENSCGRP00001000931 88.3721 84.0116 ENSG00000137074 homo_sapiens ENSP00000369145 93.5673 88.5965 pteropus_vampyrus ENSPVAP00000010811 90.3955 85.5932 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.6433 myotis_lucifugus ENSMLUP00000014650 89.7222 86.1111 ENSG00000137074 homo_sapiens ENSP00000369145 82.7485 69.2982 vombatus_ursinus ENSVURP00010016009 80.6268 67.5214 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 90.9357 rhinolophus_ferrumequinum ENSRFEP00010025704 87.062 83.8275 ENSG00000137074 homo_sapiens ENSP00000369145 95.0292 89.7661 neovison_vison ENSNVIP00000000735 95.0292 89.7661 ENSG00000137074 homo_sapiens ENSP00000369145 89.1813 84.2105 bos_taurus ENSBTAP00000066152 84.9582 80.2228 ENSG00000137074 homo_sapiens ENSP00000369145 91.8129 87.1345 heterocephalus_glaber_female ENSHGLP00000054195 91.8129 87.1345 ENSG00000137074 homo_sapiens ENSP00000369145 97.9532 96.7836 rhinopithecus_bieti ENSRBIP00000038916 91.0326 89.9457 ENSG00000137074 homo_sapiens ENSP00000369145 96.7836 92.1053 canis_lupus_dingo ENSCAFP00020019619 96.7836 92.1053 ENSG00000137074 homo_sapiens ENSP00000369145 94.4444 89.7661 sciurus_vulgaris ENSSVLP00005021338 94.4444 89.7661 ENSG00000137074 homo_sapiens ENSP00000369145 19.2982 17.5439 phascolarctos_cinereus ENSPCIP00000048960 88 80 ENSG00000137074 homo_sapiens ENSP00000369145 82.1637 69.5906 phascolarctos_cinereus ENSPCIP00000040796 80.057 67.8063 ENSG00000137074 homo_sapiens ENSP00000369145 79.5322 75.731 procavia_capensis ENSPCAP00000009315 79.5322 75.731 ENSG00000137074 homo_sapiens ENSP00000369145 90.9357 85.0877 nannospalax_galili ENSNGAP00000015247 92.0118 86.0947 ENSG00000137074 homo_sapiens ENSP00000369145 93.8596 89.1813 bos_grunniens ENSBGRP00000002057 80.6533 76.6332 ENSG00000137074 homo_sapiens ENSP00000369145 92.1053 86.5497 chinchilla_lanigera ENSCLAP00000017761 93.4718 87.8338 ENSG00000137074 homo_sapiens ENSP00000369145 87.1345 81.5789 cervus_hanglu_yarkandensis ENSCHYP00000009995 79.0451 74.0053 ENSG00000137074 homo_sapiens ENSP00000369145 94.7368 88.3041 catagonus_wagneri ENSCWAP00000023652 93.913 87.5362 ENSG00000137074 homo_sapiens ENSP00000369145 92.1053 86.2573 ictidomys_tridecemlineatus ENSSTOP00000004651 94.3114 88.3234 ENSG00000137074 homo_sapiens ENSP00000369145 95.614 91.5205 otolemur_garnettii ENSOGAP00000004822 91.8539 87.9213 ENSG00000137074 homo_sapiens ENSP00000369145 97.3684 94.152 cebus_imitator ENSCCAP00000037915 97.0845 93.8775 ENSG00000137074 homo_sapiens ENSP00000369145 93.5673 87.1345 urocitellus_parryii ENSUPAP00010009651 93.8416 87.39 ENSG00000137074 homo_sapiens ENSP00000369145 93.2749 88.8889 moschus_moschiferus ENSMMSP00000010107 91.9308 87.6081 ENSG00000137074 homo_sapiens ENSP00000369145 97.9532 96.4912 rhinopithecus_roxellana ENSRROP00000023104 94.6328 93.2203 ENSG00000137074 homo_sapiens ENSP00000369145 89.4737 84.5029 mus_pahari MGP_PahariEiJ_P0057450 90.2655 85.2507 ENSG00000137074 homo_sapiens ENSP00000369145 97.3684 94.7368 propithecus_coquereli ENSPCOP00000010620 97.3684 94.7368 ENSG00000137074 homo_sapiens ENSP00000369145 30.4094 20.4678 drosophila_melanogaster FBpp0083174 15.71 10.574 ENSG00000137074 homo_sapiens ENSP00000369145 60.2339 40.3509 ciona_intestinalis ENSCINP00000017819 54.2105 36.3158 ENSG00000137074 homo_sapiens ENSP00000369145 63.1579 47.076 petromyzon_marinus ENSPMAP00000009270 61.5385 45.8689 ENSG00000137074 homo_sapiens ENSP00000369145 65.7895 48.2456 eptatretus_burgeri ENSEBUP00000022588 61.8132 45.3297 ENSG00000137074 homo_sapiens ENSP00000369145 73.6842 59.0643 callorhinchus_milii ENSCMIP00000025922 71.5909 57.3864 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 63.1579 latimeria_chalumnae ENSLACP00000003789 70.4301 58.0645 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 62.2807 lepisosteus_oculatus ENSLOCP00000014197 71.0306 59.3315 ENSG00000137074 homo_sapiens ENSP00000369145 70.7602 57.0175 danio_rerio ENSDARP00000035368 74.6914 60.1852 ENSG00000137074 homo_sapiens ENSP00000369145 72.5146 59.0643 carassius_auratus ENSCARP00000008626 66.8464 54.4474 ENSG00000137074 homo_sapiens ENSP00000369145 72.807 58.4795 astyanax_mexicanus ENSAMXP00000030925 73.6686 59.1716 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 58.1871 ictalurus_punctatus ENSIPUP00000025931 71.9764 58.7021 ENSG00000137074 homo_sapiens ENSP00000369145 71.6374 55.848 esox_lucius ENSELUP00000068310 69.0141 53.8028 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 57.0175 electrophorus_electricus ENSEEEP00000008552 64.042 51.1811 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 57.3099 oncorhynchus_kisutch ENSOKIP00005005953 70.1149 56.3218 ENSG00000137074 homo_sapiens ENSP00000369145 71.0526 57.3099 oncorhynchus_mykiss ENSOMYP00000019041 69.8276 56.3218 ENSG00000137074 homo_sapiens ENSP00000369145 71.9298 57.3099 salmo_trutta ENSSTUP00000076727 70.6897 56.3218 ENSG00000137074 homo_sapiens ENSP00000369145 68.4211 52.3392 gadus_morhua ENSGMOP00000029225 53.0612 40.5896 ENSG00000137074 homo_sapiens ENSP00000369145 66.0819 49.1228 fundulus_heteroclitus ENSFHEP00000019400 57.6531 42.8571 ENSG00000137074 homo_sapiens ENSP00000369145 67.8363 53.8012 poecilia_reticulata ENSPREP00000006303 76.5677 60.7261 ENSG00000137074 homo_sapiens ENSP00000369145 73.0994 58.4795 xiphophorus_maculatus ENSXMAP00000026081 72.4638 57.971 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 56.7251 oryzias_latipes ENSORLP00000007838 73.2733 58.2583 ENSG00000137074 homo_sapiens ENSP00000369145 73.9766 59.3567 cyclopterus_lumpus ENSCLMP00005009784 75.976 60.961 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 59.0643 oreochromis_niloticus ENSONIP00000018299 65.4135 50.6266 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 60.2339 haplochromis_burtoni ENSHBUP00000018922 78.852 62.2356 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 60.2339 astatotilapia_calliptera ENSACLP00000027799 79.1541 62.2356 ENSG00000137074 homo_sapiens ENSP00000369145 76.0234 61.4035 sparus_aurata ENSSAUP00010042626 78.0781 63.0631 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 62.5731 lates_calcarifer ENSLCAP00010004419 78.6787 64.2643 ENSG00000137074 homo_sapiens ENSP00000369145 76.0234 61.6959 xenopus_tropicalis ENSXETP00000052107 74.928 60.8069 ENSG00000137074 homo_sapiens ENSP00000369145 75.731 65.7895 chrysemys_picta_bellii ENSCPBP00000034381 66.9251 58.1395 ENSG00000137074 homo_sapiens ENSP00000369145 78.3626 66.0819 sphenodon_punctatus ENSSPUP00000011716 66.0098 55.665 ENSG00000137074 homo_sapiens ENSP00000369145 69.883 57.6023 crocodylus_porosus ENSCPRP00005017882 58.7224 48.403 ENSG00000137074 homo_sapiens ENSP00000369145 72.807 59.6491 laticauda_laticaudata ENSLLTP00000001864 68.595 56.1983 ENSG00000137074 homo_sapiens ENSP00000369145 68.7134 57.6023 notechis_scutatus ENSNSUP00000021067 71.4286 59.8784 ENSG00000137074 homo_sapiens ENSP00000369145 71.9298 59.6491 pseudonaja_textilis ENSPTXP00000017580 70.2857 58.2857 ENSG00000137074 homo_sapiens ENSP00000369145 66.3743 57.0175 anas_platyrhynchos_platyrhynchos ENSAPLP00000015505 70.9375 60.9375 ENSG00000137074 homo_sapiens ENSP00000369145 68.7134 57.8947 gallus_gallus ENSGALP00010010965 63.8587 53.8043 ENSG00000137074 homo_sapiens ENSP00000369145 47.9532 41.2281 meleagris_gallopavo ENSMGAP00000005667 75.2294 64.6789 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 64.0351 serinus_canaria ENSSCAP00000015044 74.1279 63.6628 ENSG00000137074 homo_sapiens ENSP00000369145 73.3918 62.5731 parus_major ENSPMJP00000005568 72.9651 62.2093 ENSG00000137074 homo_sapiens ENSP00000369145 72.807 60.5263 anolis_carolinensis ENSACAP00000035642 65.5263 54.4737 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 59.6491 neolamprologus_brichardi ENSNBRP00000018416 78.852 61.6314 ENSG00000137074 homo_sapiens ENSP00000369145 72.5146 59.6491 naja_naja ENSNNAP00000020895 69.6629 57.3034 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 64.0351 geospiza_fortis ENSGFOP00000014025 63.75 54.75 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 63.1579 taeniopygia_guttata ENSTGUP00000034249 70.5556 60 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 59.9415 erpetoichthys_calabaricus ENSECRP00000033624 68.9189 55.4054 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 57.6023 kryptolebias_marmoratus ENSKMAP00000000138 76.2763 59.1592 ENSG00000137074 homo_sapiens ENSP00000369145 62.5731 48.538 salvator_merianae ENSSMRP00000010479 65.6442 50.9202 ENSG00000137074 homo_sapiens ENSP00000369145 71.6374 56.7251 oryzias_javanicus ENSOJAP00000000712 73.5736 58.2583 ENSG00000137074 homo_sapiens ENSP00000369145 71.6374 55.848 amphilophus_citrinellus ENSACIP00000002514 78.2748 61.0224 ENSG00000137074 homo_sapiens ENSP00000369145 73.9766 59.0643 dicentrarchus_labrax ENSDLAP00005003473 75.2976 60.119 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 56.4327 amphiprion_percula ENSAPEP00000024266 68.3473 54.0616 ENSG00000137074 homo_sapiens ENSP00000369145 70.7602 57.0175 oryzias_sinensis ENSOSIP00000023113 72.2388 58.209 ENSG00000137074 homo_sapiens ENSP00000369145 77.7778 67.5439 pelodiscus_sinensis ENSPSIP00000011753 74.0947 64.3454 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 65.2047 gopherus_evgoodei ENSGEVP00005027988 74.1477 63.3523 ENSG00000137074 homo_sapiens ENSP00000369145 76.0234 64.9123 chelonoidis_abingdonii ENSCABP00000017881 73.8636 63.0682 ENSG00000137074 homo_sapiens ENSP00000369145 75.1462 61.1111 seriola_dumerili ENSSDUP00000002562 78.3537 63.7195 ENSG00000137074 homo_sapiens ENSP00000369145 73.9766 59.0643 cottoperca_gobio ENSCGOP00000000408 75.7485 60.479 ENSG00000137074 homo_sapiens ENSP00000369145 67.5439 57.6023 struthio_camelus_australis ENSSCUP00000011657 71.2963 60.8025 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 64.9123 anser_brachyrhynchus ENSABRP00000005256 72.5714 63.4286 ENSG00000137074 homo_sapiens ENSP00000369145 72.2222 57.3099 gasterosteus_aculeatus ENSGACP00000023635 73.9521 58.6826 ENSG00000137074 homo_sapiens ENSP00000369145 70.4678 56.7251 cynoglossus_semilaevis ENSCSEP00000014850 72.1557 58.0838 ENSG00000137074 homo_sapiens ENSP00000369145 73.9766 58.1871 poecilia_formosa ENSPFOP00000004877 75.976 59.7598 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 58.4795 poecilia_formosa ENSPFOP00000005019 76.0479 59.8802 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 59.6491 myripristis_murdjan ENSMMDP00005000233 76.2763 61.2613 ENSG00000137074 homo_sapiens ENSP00000369145 70.1754 55.848 sander_lucioperca ENSSLUP00000032816 71.8563 57.1856 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 62.8655 strigops_habroptila ENSSHBP00005023270 72.5714 61.4286 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 60.5263 amphiprion_ocellaris ENSAOCP00000006540 78.3784 62.1622 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 65.4971 terrapene_carolina_triunguis ENSTMTP00000008592 64.604 55.4455 ENSG00000137074 homo_sapiens ENSP00000369145 72.2222 58.4795 hucho_hucho ENSHHUP00000026313 70.1705 56.8182 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 60.8187 betta_splendens ENSBSLP00000034644 76.0479 62.2754 ENSG00000137074 homo_sapiens ENSP00000369145 73.6842 57.6023 pygocentrus_nattereri ENSPNAP00000029721 73.4694 57.4344 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 59.6491 anabas_testudineus ENSATEP00000025044 76.5766 61.2613 ENSG00000137074 homo_sapiens ENSP00000369145 60.5263 39.4737 ciona_savignyi ENSCSAVP00000013710 56.0976 36.5854 ENSG00000137074 homo_sapiens ENSP00000369145 28.3626 16.0819 saccharomyces_cerevisiae YOR258W 44.7005 25.3456 ENSG00000137074 homo_sapiens ENSP00000369145 75.4386 61.4035 seriola_lalandi_dorsalis ENSSLDP00000006157 77.4775 63.0631 ENSG00000137074 homo_sapiens ENSP00000369145 69.2982 55.5556 labrus_bergylta ENSLBEP00000028488 69.7059 55.8824 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 60.5263 labrus_bergylta ENSLBEP00000020172 73.6232 60 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 60.2339 pundamilia_nyererei ENSPNYP00000010101 79.1541 62.2356 ENSG00000137074 homo_sapiens ENSP00000369145 73.6842 57.8947 mastacembelus_armatus ENSMAMP00000027330 75.6757 59.4595 ENSG00000137074 homo_sapiens ENSP00000369145 75.4386 61.4035 stegastes_partitus ENSSPAP00000027024 77.9456 63.4441 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 57.3099 oncorhynchus_tshawytscha ENSOTSP00005009770 70.1149 56.3218 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 55.5556 acanthochromis_polyacanthus ENSAPOP00000006928 66.3043 51.6304 ENSG00000137074 homo_sapiens ENSP00000369145 73.6842 63.7427 aquila_chrysaetos_chrysaetos ENSACCP00020018144 67.7419 58.6021 ENSG00000137074 homo_sapiens ENSP00000369145 71.345 56.4327 nothobranchius_furzeri ENSNFUP00015003145 72.4036 57.27 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 58.1871 cyprinodon_variegatus ENSCVAP00000009905 76.3473 59.5808 ENSG00000137074 homo_sapiens ENSP00000369145 72.807 59.3567 denticeps_clupeoides ENSDCDP00000006797 69.9438 57.0225 ENSG00000137074 homo_sapiens ENSP00000369145 76.6082 61.1111 larimichthys_crocea ENSLCRP00005025355 78.6787 62.7628 ENSG00000137074 homo_sapiens ENSP00000369145 73.6842 58.1871 takifugu_rubripes ENSTRUP00000024613 70.7865 55.8989 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 64.0351 ficedula_albicollis ENSFALP00000001280 68.4636 59.0296 ENSG00000137074 homo_sapiens ENSP00000369145 72.2222 57.6023 hippocampus_comes ENSHCOP00000014749 74.8485 59.697 ENSG00000137074 homo_sapiens ENSP00000369145 71.9298 57.8947 cyprinus_carpio_carpio ENSCCRP00000093966 71.7201 57.7259 ENSG00000137074 homo_sapiens ENSP00000369145 71.6374 57.8947 cyprinus_carpio_carpio ENSCCRP00000039795 67.4931 54.5455 ENSG00000137074 homo_sapiens ENSP00000369145 67.2515 53.2164 coturnix_japonica ENSCJPP00005003533 49.569 39.2241 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 58.4795 poecilia_latipinna ENSPLAP00000005919 76.2763 60.0601 ENSG00000137074 homo_sapiens ENSP00000369145 74.269 58.4795 poecilia_latipinna ENSPLAP00000022946 76.2763 60.0601 ENSG00000137074 homo_sapiens ENSP00000369145 63.4503 51.462 sinocyclocheilus_grahami ENSSGRP00000029580 69.3291 56.23 ENSG00000137074 homo_sapiens ENSP00000369145 66.3743 51.7544 sinocyclocheilus_grahami ENSSGRP00000041210 65.7971 51.3043 ENSG00000137074 homo_sapiens ENSP00000369145 76.3158 59.9415 maylandia_zebra ENSMZEP00005030354 78.852 61.9335 ENSG00000137074 homo_sapiens ENSP00000369145 72.2222 57.8947 tetraodon_nigroviridis ENSTNIP00000000457 72.2222 57.8947 ENSG00000137074 homo_sapiens ENSP00000369145 75.731 61.6959 paramormyrops_kingsleyae ENSPKIP00000034170 74.4253 60.6322 ENSG00000137074 homo_sapiens ENSP00000369145 75.4386 64.6199 scleropages_formosus ENSSFOP00015014380 73.0878 62.6062 ENSG00000137074 homo_sapiens ENSP00000369145 74.5614 60.5263 leptobrachium_leishanense ENSLLEP00000010287 73.913 60 ENSG00000137074 homo_sapiens ENSP00000369145 75.4386 61.1111 scophthalmus_maximus ENSSMAP00000014444 76.1062 61.6519 ENSG00000137074 homo_sapiens ENSP00000369145 66.9591 51.462 oryzias_melastigma ENSOMEP00000006809 64.1457 49.2997
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000012 involved_in single strand break repair 3 IBA,IDA,IMP Homo_sapiens(9606) Process GO:0000785 part_of chromatin 1 IDA Homo_sapiens(9606) Component GO:0003682 enables chromatin binding 1 IDA Homo_sapiens(9606) Function GO:0003684 enables damaged DNA binding 1 IDA Homo_sapiens(9606) Function GO:0003690 enables double-stranded DNA binding 1 IDA Homo_sapiens(9606) Function GO:0003697 enables single-stranded DNA binding 1 IBA Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 1 IBA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0006266 involved_in DNA ligation 1 IEA Homo_sapiens(9606) Process GO:0008967 enables phosphoglycolate phosphatase activity 1 IDA Homo_sapiens(9606) Function GO:0030983 enables mismatched DNA binding 1 IBA Homo_sapiens(9606) Function GO:0031647 involved_in regulation of protein stability 1 IMP Homo_sapiens(9606) Process GO:0033699 enables DNA 5-adenosine monophosphate hydrolase activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0051219 enables phosphoprotein binding 1 IPI Homo_sapiens(9606) Function GO:0120108 enables DNA-3-diphospho-5-guanosine diphosphatase 1 IEA Homo_sapiens(9606) Function GO:1990165 enables single-strand break-containing DNA binding 1 IBA Homo_sapiens(9606) Function
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