Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2Dengue
Drug Drug
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000136937 Gene ID 4686 Accession 7658
Symbol NCBP1 Alias NCBP;Sto1;CBP80 Full Name nuclear cap binding protein subunit 1
Status Confidence Length 40081 bases Strand Plus strand
Position 9 : 97633668 - 97673748 RNA binding domain MIF4G_like , MIF4G_like_2 , MIF4G
Summary The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Protein-Protein Interaction (PPI)

Orthologs

Gene Ontology

Expression