Ensembl ID
ENSG00000136937
Gene ID
4686
Accession
7658
Gene Symbol
NCBP1
Alias
NCBP;Sto1;CBP80
Full Name
nuclear cap binding protein subunit 1
Position
9 : 97633668 - 97673748
Length
40081 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]
ENSG00000136937 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000136937
NCBP1
0.46
2.28e-23
BRCA
ENSG00000136937
NCBP1
0.67
2.12e-19
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000136937
NCBP1
tumour
20379136
ENSG00000136937
NCBP1
prostate cancer
23251452
ENSG00000136937
NCBP1
ovarian tumor
25286318
ENSG00000136937
NCBP1
tumour
31448526
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000136937
NCBP1
SARC
0.0054
high
show
ENSG00000136937
NCBP1
LGG
0.00013
high
show
ENSG00000136937
NCBP1
LUSC
0.027
low
show
ENSG00000136937
NCBP1
KICH
0.00011
high
show
ENSG00000136937
NCBP1
LUAD
0.00074
high
show
ENSG00000136937
NCBP1
THYM
0.0061
low
show
ENSG00000136937
NCBP1
BRCA
0.00082
high
show
ENSG00000136937
NCBP1
COAD
0.015
low
show
ENSG00000136937
NCBP1
UCS
0.012
high
show
ENSG00000136937
NCBP1
ESCA
0.022
high
show
ENSG00000136937
NCBP1
DLBC
0.0092
low
show
ENSG00000136937
NCBP1
PRAD
0.00027
high
show
ENSG00000136937
NCBP1
BLCA
0.046
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000136937
NCBP1
UCEC
Del
0.610741
0.046198
0.534811
0.256030
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