Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug Drug
Main interacting RNAs ncRNA
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000136807 Gene ID 1025 Accession 1780
Symbol CDK9 Alias TAK;C-2k;CTK1;CDC2L4;PITALRE Full Name cyclin dependent kinase 9
Status Confidence Length 5114 bases Strand Plus strand
Position 9 : 127785679 - 127790792 RNA binding domain N.A.
Summary The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
33717648 Lnc(ing)RNAs to the 'shock and kill' strategy for HIV-1 cure. Saikat Boliar 2021-03-05 Molecular therapy. Nucleic acids
24694320 A novel, non-radioactive eukaryotic in vitro transcription assay for sensitive quantification of RNA polymerase II activity. Cristina Voss 2014-04-03 BMC molecular biology
31020497 Tat expression led to increased histone 3 tri-methylation at lysine 27 and contributed to HIV latency in astrocytes through regulation of MeCP2 and Ezh2 expression. Ying Liu 2019-08-01 Journal of neurovirology
21205204 Phosphorylation mechanism and structure of serine-arginine protein kinases. Gourisankar Ghosh 2011-02-01 The FEBS journal
22672903 A role for CDK9 in UV damage response. E Magdalena Morawska 2012-06-15 Cell cycle (Georgetown, Tex.)
31953354 IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins. Lihua Shi 2020-03-01 Journal of immunology (Baltimore, Md. : 1950)
35693926 Inhibition of Cyclin-Dependent Kinase 9 Downregulates Cytokine Production Without Detrimentally Affecting Human Monocyte-Derived Macrophage Viability. J Brian McHugh 2022-01-01 Frontiers in cell and developmental biology
32778962 Repurposing of Kinase Inhibitors for Treatment of COVID-19. Ellen Weisberg 2020-08-10 Pharmaceutical research
27171036 Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy. A Yogesh Sonawane 2016-10-13 Journal of medicinal chemistry
22140483 A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function. Rajeev Mehla 2011-01-01 PloS one
35856391 hnRNP R negatively regulates transcription by modulating the association of P-TEFb with 7SK and BRD4. Changhe Ji 2022-09-05 EMBO reports
30080437 JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states. Lusy Handoko 2018-01-01 Epigenetics
30613326 Privileged Structures and Polypharmacology within and between Protein Families. Joshua Meyers 2018-12-13 ACS medicinal chemistry letters

Transcripts

Name Transcript ID bp Protein Translation ID
CDK9-202 ENST00000421939 702 194aa ENSP00000395872
CDK9-201 ENST00000373264 2483 372aa ENSP00000362361
CDK9-203 ENST00000480353 706 No protein -
CDK9-204 ENST00000491521 510 No protein -
CDK9-205 ENST00000498339 458 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136807homo_sapiensENSP0000033719414.10138.54022homo_sapiensENSP0000036236138.17223.1183
ENSG00000136807homo_sapiensENSP0000018183915.674611.1111homo_sapiensENSP0000036236163.709745.1613
ENSG00000136807homo_sapiensENSP0000049860839.310327.3563homo_sapiensENSP0000036236145.967731.9892
ENSG00000136807homo_sapiensENSP0000048524417.604211.4583homo_sapiensENSP0000036236145.430129.5699
ENSG00000136807homo_sapiensENSP0000026121135.946522.3709homo_sapiensENSP0000036236150.537631.4516
ENSG00000136807homo_sapiensENSP0000037093838.577625.431homo_sapiensENSP0000036236148.118331.7204
ENSG00000136807homo_sapiensENSP0000026697056.711439.2617homo_sapiensENSP0000036236145.430131.4516
ENSG00000136807homo_sapiensENSP0000032234347.976934.3931homo_sapiensENSP0000036236144.623731.9892
ENSG00000136807homo_sapiensENSP0000034976237.903226.0081homo_sapiensENSP0000036236150.537634.6774
ENSG00000136807homo_sapiensENSP0000033867348.888933.3333homo_sapiensENSP0000036236147.311832.2581
ENSG00000136807homo_sapiensENSP0000046304824.040915.4731homo_sapiensENSP0000036236150.537632.5269
ENSG00000136807homo_sapiensENSP0000038444224.230815.5128homo_sapiensENSP0000036236150.806432.5269
ENSG00000136807homo_sapiensENSP0000025790452.805334.9835homo_sapiensENSP0000036236143.010828.4946
ENSG00000136807homo_sapiensENSP0000030634031.228118.4211homo_sapiensENSP0000036236147.849528.2258
ENSG00000136807homo_sapiensENSP0000025644350.57835.5491homo_sapiensENSP0000036236147.04333.0645
ENSG00000136807homo_sapiensENSP0000039888016.040311.2752homo_sapiensENSP0000036236164.247345.1613
ENSG00000136807homo_sapiensENSP0000026533429.560817.9054homo_sapiensENSP0000036236147.04328.4946
ENSG00000136807homo_sapiensENSP0000039708752.45434.0491homo_sapiensENSP0000036236145.967729.8387
ENSG00000136807homo_sapiensENSP0000051448648.830430.117homo_sapiensENSP0000036236144.892527.6882
ENSG00000136807homo_sapiensENSP0000041978257.191840.0685homo_sapiensENSP0000036236144.892531.4516
ENSG00000136807homo_sapiensENSP0000039908238.185726.1603homo_sapiensENSP0000036236148.655933.3333
ENSG00000136807homo_sapiensENSP0000036939037.739925.1599homo_sapiensENSP0000036236147.580631.7204
ENSG00000136807homo_sapiensENSP0000040008855.08238.3607homo_sapiensENSP0000036236145.161331.4516
ENSG00000136807homo_sapiensENSP0000037869958.585939.7306homo_sapiensENSP0000036236146.774231.7204
ENSG00000136807homo_sapiensENSP0000037917648.739530.5322homo_sapiensENSP0000036236146.774229.3011
ENSG00000136807homo_sapiensENSP0000035790735.856623.9044homo_sapiensENSP0000036236148.387132.2581

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136807homo_sapiensENSP0000036236196.774295.9677nomascus_leucogenysENSNLEP0000002123596.774295.9677
ENSG00000136807homo_sapiensENSP00000362361100100pan_paniscusENSPPAP00000024837100100
ENSG00000136807homo_sapiensENSP0000036236199.731299.7312pongo_abeliiENSPPYP0000002199975.714375.7143
ENSG00000136807homo_sapiensENSP00000362361100100pan_troglodytesENSPTRP00000036573100100
ENSG00000136807homo_sapiensENSP00000362361100100gorilla_gorillaENSGGOP00000010772100100
ENSG00000136807homo_sapiensENSP0000036236179.032372.3118ornithorhynchus_anatinusENSOANP000000405567568.6225
ENSG00000136807homo_sapiensENSP0000036236195.698992.7419sarcophilus_harrisiiENSSHAP0000003766370.49568.3168
ENSG00000136807homo_sapiensENSP0000036236173.387170.6989notamacropus_eugeniiENSMEUP0000001189059.477157.2985
ENSG00000136807homo_sapiensENSP0000036236198.924797.5806dasypus_novemcinctusENSDNOP0000003273075.564774.538
ENSG00000136807homo_sapiensENSP0000036236158.602158.0645erinaceus_europaeusENSEEUP0000001200952.028651.5513
ENSG00000136807homo_sapiensENSP0000036236190.322687.9032echinops_telfairiENSETEP0000000684768.993867.1458
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247callithrix_jacchusENSCJAP0000003692876.180775.5647
ENSG00000136807homo_sapiensENSP00000362361100100cercocebus_atysENSCATP00000037570100100
ENSG00000136807homo_sapiensENSP00000362361100100macaca_fascicularisENSMFAP00000035326100100
ENSG00000136807homo_sapiensENSP00000362361100100macaca_mulattaENSMMUP00000073882100100
ENSG00000136807homo_sapiensENSP00000362361100100macaca_nemestrinaENSMNEP00000031396100100
ENSG00000136807homo_sapiensENSP00000362361100100papio_anubisENSPANP0000001937276.229576.2295
ENSG00000136807homo_sapiensENSP00000362361100100mandrillus_leucophaeusENSMLEP00000003030100100
ENSG00000136807homo_sapiensENSP0000036236198.118397.043tursiops_truncatusENSTTRP0000001560574.948774.1273
ENSG00000136807homo_sapiensENSP0000036236199.462498.1183vulpes_vulpesENSVVUP0000001802399.462498.1183
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559mus_spretusMGP_SPRETEiJ_P005322699.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871equus_asinusENSEASP0000504958970.208769.4497
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559capra_hircusENSCHIP0000002977299.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871loxodonta_africanaENSLAFP0000001412899.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495panthera_leoENSPLOP0000002700175.356474.1344
ENSG00000136807homo_sapiensENSP0000036236199.193697.8495ailuropoda_melanoleucaENSAMEP0000002390366.12965.233
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559bos_indicus_hybridENSBIXP0000501154675.101274.2915
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559equus_caballusENSECAP0000003662574.898874.2915
ENSG00000136807homo_sapiensENSP0000036236199.462498.1183canis_lupus_familiarisENSCAFP0084500746275.664674.6421
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495panthera_pardusENSPPRP0000002009799.462497.8495
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871marmota_marmota_marmotaENSMMMP0000001947599.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559balaenoptera_musculusENSBMSP0001000584075.819775.2049
ENSG00000136807homo_sapiensENSP0000036236199.731298.3871cavia_porcellusENSCPOP0000000930599.731298.3871
ENSG00000136807homo_sapiensENSP0000036236179.032373.1183cavia_porcellusENSCPOP0000000815187.240480.7122
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495felis_catusENSFCAP0000002874475.203373.9837
ENSG00000136807homo_sapiensENSP0000036236199.193697.8495ursus_americanusENSUAMP0000002975499.193697.8495
ENSG00000136807homo_sapiensENSP0000036236195.698992.7419monodelphis_domesticaENSMODP0000004085170.078767.9134
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559bison_bison_bisonENSBBBP0000002556699.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.193698.3871monodon_monocerosENSMMNP0001502887499.193698.3871
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559sus_scrofaENSSSCP0000000602299.462498.6559
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871microcebus_murinusENSMICP0000004369399.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871octodon_degusENSODEP0000000523199.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.731298.3871jaculus_jaculusENSJJAP0000001486799.731298.3871
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559ovis_aries_rambouilletENSOARP0002002038899.731298.6559
ENSG00000136807homo_sapiensENSP0000036236193.010790.8602ursus_maritimusENSUMAP0000000062593.010790.8602
ENSG00000136807homo_sapiensENSP0000036236199.193698.3871delphinapterus_leucasENSDLEP0000001938975.614875
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871physeter_catodonENSPCTP0000501222599.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559mus_caroliMGP_CAROLIEiJ_P005118699.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559mus_musculusENSMUSP0000000969999.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495dipodomys_ordiiENSDORP0000001253099.462497.8495
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495mustela_putorius_furoENSMPUP0000001357899.462497.8495
ENSG00000136807homo_sapiensENSP0000036236193.279691.9355aotus_nancymaaeENSANAP0000004086896.388995
ENSG00000136807homo_sapiensENSP0000036236188.978585.7527aotus_nancymaaeENSANAP0000002601894.034190.625
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247aotus_nancymaaeENSANAP0000004208099.731298.9247
ENSG00000136807homo_sapiensENSP0000036236185.215180.914saimiri_boliviensis_boliviensisENSSBOP0000002712286.61282.2404
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247saimiri_boliviensis_boliviensisENSSBOP0000001328999.731298.9247
ENSG00000136807homo_sapiensENSP0000036236162.096861.2903vicugna_pacosENSVPAP0000000447067.941267.0588
ENSG00000136807homo_sapiensENSP00000362361100100chlorocebus_sabaeusENSCSAP0000000995876.229576.2295
ENSG00000136807homo_sapiensENSP0000036236199.731298.1183mesocricetus_auratusENSMAUP0000002329599.731298.1183
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559phocoena_sinusENSPSNP0000001419975.819775.2049
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559camelus_dromedariusENSCDRP0000501864799.462498.6559
ENSG00000136807homo_sapiensENSP0000036236191.12990.5914carlito_syrichtaENSTSYP0000001705499.413598.827
ENSG00000136807homo_sapiensENSP0000036236191.12989.7849panthera_tigris_altaicaENSPTIP0000000185091.12989.7849
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559rattus_norvegicusENSRNOP0000003777875.560174.7454
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247prolemur_simusENSPSMP0000001159799.731298.9247
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559microtus_ochrogasterENSMOCP0000002621899.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559peromyscus_maniculatus_bairdiiENSPEMP0000000896499.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559bos_mutusENSBMUP0000002525599.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559mus_spicilegusENSMSIP0000001177076.180775.3593
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559cricetulus_griseus_chok1gshdENSCGRP0000101335775.869175.0511
ENSG00000136807homo_sapiensENSP0000036236199.193698.1183pteropus_vampyrusENSPVAP0000000091176.082575.2577
ENSG00000136807homo_sapiensENSP0000036236197.311895.9677myotis_lucifugusENSMLUP0000001227197.050995.7105
ENSG00000136807homo_sapiensENSP0000036236193.548489.7849myotis_lucifugusENSMLUP0000001317793.548489.7849
ENSG00000136807homo_sapiensENSP0000036236191.12986.828myotis_lucifugusENSMLUP0000001918491.12986.828
ENSG00000136807homo_sapiensENSP0000036236194.892592.2043myotis_lucifugusENSMLUP0000001909394.892592.2043
ENSG00000136807homo_sapiensENSP0000036236191.666789.2473myotis_lucifugusENSMLUP0000002193291.666789.2473
ENSG00000136807homo_sapiensENSP0000036236195.698992.7419vombatus_ursinusENSVURP0001002103595.442492.4933
ENSG00000136807homo_sapiensENSP0000036236199.193698.1183rhinolophus_ferrumequinumENSRFEP0001002302975.614874.7951
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495neovison_visonENSNVIP0000001318099.462497.8495
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559bos_taurusENSBTAP0000000616299.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.462497.8495heterocephalus_glaber_femaleENSHGLP0000001756275.975474.7433
ENSG00000136807homo_sapiensENSP00000362361100100rhinopithecus_bietiENSRBIP00000030488100100
ENSG00000136807homo_sapiensENSP0000036236199.462498.1183canis_lupus_dingoENSCAFP0002001988275.664674.6421
ENSG00000136807homo_sapiensENSP0000036236199.462498.1183sciurus_vulgarisENSSVLP0000501798776.131775.1029
ENSG00000136807homo_sapiensENSP0000036236165.322664.2473procavia_capensisENSPCAP0000000828969.827668.6782
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247nannospalax_galiliENSNGAP0000001788599.731298.9247
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559bos_grunniensENSBGRP0000001054675.101274.2915
ENSG00000136807homo_sapiensENSP0000036236197.849597.043chinchilla_lanigeraENSCLAP0000001212797.849597.043
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559cervus_hanglu_yarkandensisENSCHYP0000002738199.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247catagonus_wagneriENSCWAP0000001497876.024675.4098
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871ictidomys_tridecemlineatusENSSTOP0000000741299.462498.3871
ENSG00000136807homo_sapiensENSP0000036236199.462498.6559otolemur_garnettiiENSOGAP0000000725399.462498.6559
ENSG00000136807homo_sapiensENSP0000036236199.731298.9247cebus_imitatorENSCCAP0000003248199.731298.9247
ENSG00000136807homo_sapiensENSP0000036236182.795780.1075cebus_imitatorENSCCAP0000001388293.051490.0302
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871urocitellus_parryiiENSUPAP0001001808876.131775.3086
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559moschus_moschiferusENSMMSP0000002775399.731298.6559
ENSG00000136807homo_sapiensENSP00000362361100100rhinopithecus_roxellanaENSRROP00000034594100100
ENSG00000136807homo_sapiensENSP0000036236199.731298.6559mus_pahariMGP_PahariEiJ_P006219799.731298.6559
ENSG00000136807homo_sapiensENSP0000036236199.462498.3871propithecus_coquereliENSPCOP0000002378599.462498.3871
ENSG00000136807homo_sapiensENSP0000036236170.698953.7634caenorhabditis_elegansH25P06.2b.155.020941.841
ENSG00000136807homo_sapiensENSP0000036236183.064571.2366drosophila_melanogasterFBpp007184876.485165.5941
ENSG00000136807homo_sapiensENSP0000036236182.526973.3871ciona_intestinalisENSCINP0000001800281.648972.6064
ENSG00000136807homo_sapiensENSP0000036236139.516136.5591petromyzon_marinusENSPMAP0000000686686.982280.4734
ENSG00000136807homo_sapiensENSP0000036236189.516183.3333eptatretus_burgeriENSEBUP0000001726088.563882.4468
ENSG00000136807homo_sapiensENSP0000036236181.451676.6129callorhinchus_miliiENSCMIP0000003425988.081482.8488
ENSG00000136807homo_sapiensENSP0000036236194.623790.0538latimeria_chalumnaeENSLACP0000001939794.623790.0538
ENSG00000136807homo_sapiensENSP0000036236170.967768.8172lepisosteus_oculatusENSLOCP0000000639892.957790.1408
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409clupea_harengusENSCHAP0000001319592.533387.7333
ENSG00000136807homo_sapiensENSP0000036236193.817289.5161danio_rerioENSDARP0000006585888.804184.7328
ENSG00000136807homo_sapiensENSP0000036236193.548488.4409carassius_auratusENSCARP0000004145088.549683.715
ENSG00000136807homo_sapiensENSP0000036236192.473187.0968carassius_auratusENSCARP0000006857288.888983.7209
ENSG00000136807homo_sapiensENSP0000036236193.548488.4409carassius_auratusENSCARP0000008580088.549683.715
ENSG00000136807homo_sapiensENSP0000036236190.591484.4086carassius_auratusENSCARP0000006912287.305781.3472
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409astyanax_mexicanusENSAMXP0000001375375.9371.9912
ENSG00000136807homo_sapiensENSP0000036236192.741987.0968ictalurus_punctatusENSIPUP0000003169887.563582.2335
ENSG00000136807homo_sapiensENSP0000036236193.010788.172ictalurus_punctatusENSIPUP0000003165587.817383.2487
ENSG00000136807homo_sapiensENSP0000036236191.666786.0215esox_luciusENSELUP0000003942987.660782.2622
ENSG00000136807homo_sapiensENSP0000036236193.279688.9785electrophorus_electricusENSEEEP0000002523592.533388.2667
ENSG00000136807homo_sapiensENSP0000036236193.279688.7097oncorhynchus_kisutchENSOKIP0000508893292.780788.2353
ENSG00000136807homo_sapiensENSP0000036236193.279688.7097oncorhynchus_mykissENSOMYP0000009151792.780788.2353
ENSG00000136807homo_sapiensENSP0000036236193.279688.9785salmo_salarENSSSAP0000009003188.295284.2239
ENSG00000136807homo_sapiensENSP0000036236193.279688.7097salmo_truttaENSSTUP0000003980592.780788.2353
ENSG00000136807homo_sapiensENSP0000036236192.741988.172gadus_morhuaENSGMOP0000006399480.607576.6355
ENSG00000136807homo_sapiensENSP0000036236193.548488.4409fundulus_heteroclitusENSFHEP0000002328883.054978.5203
ENSG00000136807homo_sapiensENSP0000036236182.526975.8064poecilia_reticulataENSPREP0000001120355.615951.087
ENSG00000136807homo_sapiensENSP0000036236193.010788.172xiphophorus_maculatusENSXMAP0000000385188.040783.4606
ENSG00000136807homo_sapiensENSP0000036236193.010788.9785oryzias_latipesENSORLP0000002288488.040784.2239
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097cyclopterus_lumpusENSCLMP0000502820588.549683.9695
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785oreochromis_niloticusENSONIP0000001586188.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785haplochromis_burtoniENSHBUP0000002906288.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785astatotilapia_callipteraENSACLP0000000781888.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.010788.4409sparus_aurataENSSAUP0001001855785.643681.4356
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097lates_calcariferENSLCAP0001002507293.048188.2353
ENSG00000136807homo_sapiensENSP0000036236194.354889.7849xenopus_tropicalisENSXETP0000003152793.351188.8298
ENSG00000136807homo_sapiensENSP0000036236194.892591.9355chrysemys_picta_belliiENSCPBP0000003628994.892591.9355
ENSG00000136807homo_sapiensENSP0000036236190.322686.828sphenodon_punctatusENSSPUP0000002374289.124785.6764
ENSG00000136807homo_sapiensENSP0000036236194.08691.3979crocodylus_porosusENSCPRP0000500032686.206983.7438
ENSG00000136807homo_sapiensENSP0000036236194.08690.3226laticauda_laticaudataENSLLTP0000000496894.08690.3226
ENSG00000136807homo_sapiensENSP0000036236188.978584.6774notechis_scutatusENSNSUP0000000074289.945785.5978
ENSG00000136807homo_sapiensENSP0000036236194.623791.129pseudonaja_textilisENSPTXP0000001097986.913683.7037
ENSG00000136807homo_sapiensENSP0000036236187.634484.9462anas_platyrhynchos_platyrhynchosENSAPLP0000002857780.893378.4119
ENSG00000136807homo_sapiensENSP0000036236194.354891.9355gallus_gallusENSGALP0001004182080.875678.8018
ENSG00000136807homo_sapiensENSP0000036236188.709784.9462meleagris_gallopavoENSMGAP0000000347576.566173.3179
ENSG00000136807homo_sapiensENSP0000036236194.623792.2043serinus_canariaENSSCAP0000000844285.024282.8502
ENSG00000136807homo_sapiensENSP0000036236194.623792.2043parus_majorENSPMJP0000001241594.623792.2043
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785neolamprologus_brichardiENSNBRP0000000538793.548488.9785
ENSG00000136807homo_sapiensENSP0000036236186.82882.5269naja_najaENSNNAP0000002968688.493184.1096
ENSG00000136807homo_sapiensENSP0000036236194.354890.8602podarcis_muralisENSPMRP0000002543486.666783.4568
ENSG00000136807homo_sapiensENSP0000036236188.440986.0215geospiza_fortisENSGFOP0000000603889.645887.1935
ENSG00000136807homo_sapiensENSP0000036236194.623792.2043taeniopygia_guttataENSTGUP0000000369890.025687.7238
ENSG00000136807homo_sapiensENSP0000036236187.365683.6021erpetoichthys_calabaricusENSECRP0000002459189.285785.4396
ENSG00000136807homo_sapiensENSP0000036236193.010788.9785kryptolebias_marmoratusENSKMAP0000000751888.040784.2239
ENSG00000136807homo_sapiensENSP0000036236194.354891.129salvator_merianaeENSSMRP0000001431494.354891.129
ENSG00000136807homo_sapiensENSP0000036236193.548489.2473oryzias_javanicusENSOJAP0000003109288.549684.4784
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097amphilophus_citrinellusENSACIP0000001569793.048188.2353
ENSG00000136807homo_sapiensENSP0000036236193.279688.7097dicentrarchus_labraxENSDLAP0000502739188.295283.9695
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097amphiprion_perculaENSAPEP0000001588488.549683.9695
ENSG00000136807homo_sapiensENSP0000036236159.677456.4516oryzias_sinensisENSOSIP0000000324488.884
ENSG00000136807homo_sapiensENSP0000036236188.978585.2151pelodiscus_sinensisENSPSIP0000001366689.701985.9079
ENSG00000136807homo_sapiensENSP0000036236194.892591.9355gopherus_evgoodeiENSGEVP0000502693294.892591.9355
ENSG00000136807homo_sapiensENSP0000036236194.892591.9355chelonoidis_abingdoniiENSCABP0000000230994.892591.9355
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785seriola_dumeriliENSSDUP0000002573688.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785cottoperca_gobioENSCGOP0000003074188.549684.2239
ENSG00000136807homo_sapiensENSP0000036236187.096883.871struthio_camelus_australisENSSCUP0000002339691.011287.6404
ENSG00000136807homo_sapiensENSP0000036236194.08691.3979anser_brachyrhynchusENSABRP0000000063794.08691.3979
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785gasterosteus_aculeatusENSGACP0000002448093.548488.9785
ENSG00000136807homo_sapiensENSP0000036236192.741988.7097cynoglossus_semilaevisENSCSEP0000001541187.786383.9695
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409poecilia_formosaENSPFOP0000000533188.295283.715
ENSG00000136807homo_sapiensENSP0000036236156.989249.1936myripristis_murdjanENSMMDP0000500368969.736860.1974
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785myripristis_murdjanENSMMDP0000500635893.048188.5027
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409sander_luciopercaENSSLUP0000004631787.185982.6633
ENSG00000136807homo_sapiensENSP0000036236194.354892.2043strigops_habroptilaENSSHBP0000501911694.354892.2043
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097amphiprion_ocellarisENSAOCP0000002469688.549683.9695
ENSG00000136807homo_sapiensENSP0000036236194.892591.9355terrapene_carolina_triunguisENSTMTP0000002997494.892591.9355
ENSG00000136807homo_sapiensENSP0000036236193.279688.9785hucho_huchoENSHHUP0000008058392.780788.5027
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097betta_splendensENSBSLP0000003367988.549683.9695
ENSG00000136807homo_sapiensENSP0000036236193.279688.9785pygocentrus_nattereriENSPNAP0000002294488.520484.4388
ENSG00000136807homo_sapiensENSP0000036236193.279687.9032anabas_testudineusENSATEP0000001087788.295283.2061
ENSG00000136807homo_sapiensENSP0000036236182.795773.6559ciona_savignyiENSCSAVP0000001122682.352973.262
ENSG00000136807homo_sapiensENSP0000036236157.526937.6344saccharomyces_cerevisiaeYPR161C32.572321.309
ENSG00000136807homo_sapiensENSP0000036236193.548488.7097seriola_lalandi_dorsalisENSSLDP0000002239193.048188.2353
ENSG00000136807homo_sapiensENSP0000036236193.010788.4409labrus_bergyltaENSLBEP0000002802193.010788.4409
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785pundamilia_nyerereiENSPNYP0000000438388.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785mastacembelus_armatusENSMAMP0000006270079.633975.7437
ENSG00000136807homo_sapiensENSP0000036236193.279688.7097stegastes_partitusENSSPAP0000001540988.295283.9695
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785acanthochromis_polyacanthusENSAPOP0000001028393.548488.9785
ENSG00000136807homo_sapiensENSP0000036236194.08691.3979aquila_chrysaetos_chrysaetosENSACCP0002002482594.08691.3979
ENSG00000136807homo_sapiensENSP0000036236192.473187.9032nothobranchius_furzeriENSNFUP0001500274887.531883.2061
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409cyprinodon_variegatusENSCVAP0000000347393.279688.4409
ENSG00000136807homo_sapiensENSP0000036236192.473187.6344denticeps_clupeoidesENSDCDP0000004786487.531882.9517
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409larimichthys_croceaENSLCRP0000500954093.029588.2038
ENSG00000136807homo_sapiensENSP0000036236193.010788.4409takifugu_rubripesENSTRUP0000002256888.265383.9286
ENSG00000136807homo_sapiensENSP0000036236194.623792.2043ficedula_albicollisENSFALP0000000139576.355874.4035
ENSG00000136807homo_sapiensENSP0000036236193.010788.9785hippocampus_comesENSHCOP0000000152685.856182.134
ENSG00000136807homo_sapiensENSP0000036236193.548488.4409cyprinus_carpio_carpioENSCCRP0000011236788.324983.5025
ENSG00000136807homo_sapiensENSP0000036236193.548488.4409cyprinus_carpio_carpioENSCCRP0000013374288.549683.715
ENSG00000136807homo_sapiensENSP0000036236194.354891.9355coturnix_japonicaENSCJPP0000502539494.354891.9355
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409poecilia_latipinnaENSPLAP0000001615488.295283.715
ENSG00000136807homo_sapiensENSP0000036236193.548488.172sinocyclocheilus_grahamiENSSGRP0000006405388.549683.4606
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785maylandia_zebraENSMZEP0000500104488.549684.2239
ENSG00000136807homo_sapiensENSP0000036236178.763475.5376tetraodon_nigroviridisENSTNIP0000000494593.312189.4904
ENSG00000136807homo_sapiensENSP0000036236193.010788.4409tetraodon_nigroviridisENSTNIP0000002183293.010788.4409
ENSG00000136807homo_sapiensENSP0000036236193.279687.9032paramormyrops_kingsleyaeENSPKIP0000000407381.839677.1226
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785scleropages_formosusENSSFOP0001502259388.549684.2239
ENSG00000136807homo_sapiensENSP0000036236193.279688.4409leptobrachium_leishanenseENSLLEP0000002031592.042487.2679
ENSG00000136807homo_sapiensENSP0000036236193.548488.9785scophthalmus_maximusENSSMAP0000001118288.549684.2239
ENSG00000136807homo_sapiensENSP0000036236184.677481.1828oryzias_melastigmaENSOMEP0000000382091.836788.0466

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IEAHomo_sapiens(9606)Function
GO:0001223enables transcription coactivator binding1IPIHomo_sapiens(9606)Function
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1ISSHomo_sapiens(9606)Function
GO:0004672enables protein kinase activity1TASHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity2IDA,TASHomo_sapiens(9606)Function
GO:0004693enables cyclin-dependent protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair1IEAHomo_sapiens(9606)Process
GO:0006282involved_in regulation of DNA repair1IDAHomo_sapiens(9606)Process
GO:0006366involved_in transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0006367involved_in transcription initiation at RNA polymerase II promoter1TASHomo_sapiens(9606)Process
GO:0006368involved_in transcription elongation by RNA polymerase II1TASHomo_sapiens(9606)Process
GO:0006468involved_in protein phosphorylation3IBA,IDAHomo_sapiens(9606)Process
GO:0007346NOT involved_in regulation of mitotic cell cycle1IMPHomo_sapiens(9606)Process
GO:0008023part_of transcription elongation factor complex1IDAHomo_sapiens(9606)Component
GO:0008024part_of cyclin/CDK positive transcription elongation factor complex2IDA,IPIHomo_sapiens(9606)Component
GO:0008283involved_in cell population proliferation1TASHomo_sapiens(9606)Process
GO:0008353enables RNA polymerase II CTD heptapeptide repeat kinase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016301enables kinase activity1IDAHomo_sapiens(9606)Function
GO:0016605located_in PML body1IDAHomo_sapiens(9606)Component
GO:0019901enables protein kinase binding1IEAHomo_sapiens(9606)Function
GO:0031297involved_in replication fork processing1IDAHomo_sapiens(9606)Process
GO:0031440involved_in regulation of mRNA 3-end processing1IMPHomo_sapiens(9606)Process
GO:0032968involved_in positive regulation of transcription elongation by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0036464located_in cytoplasmic ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0043923involved_in positive regulation by host of viral transcription2IDA,ISSHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0051147involved_in regulation of muscle cell differentiation1IMPHomo_sapiens(9606)Process
GO:0051647involved_in nucleus localization1IDAHomo_sapiens(9606)Process
GO:0051726involved_in regulation of cell cycle1IDAHomo_sapiens(9606)Process
GO:0070691part_of P-TEFb complex1IDAHomo_sapiens(9606)Component
GO:0071345involved_in cellular response to cytokine stimulus1IDAHomo_sapiens(9606)Process
GO:0097322enables 7SK snRNA binding1IDAHomo_sapiens(9606)Function
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function
GO:0120186involved_in negative regulation of protein localization to chromatin1IDAHomo_sapiens(9606)Process
GO:0120187involved_in positive regulation of protein localization to chromatin1IDAHomo_sapiens(9606)Process
GO:0140673involved_in transcription elongation-coupled chromatin remodeling1IDAHomo_sapiens(9606)Process

Expression