Welcome to
RBP World!
Functions and Diseases
RBP Type | Canonical_RBPs |
Diseases | Cancer |
Drug | N.A. |
Main interacting RNAs | mRNA |
Moonlighting functions | N.A. |
Localizations | N.A. |
BulkPerturb-seq | N.A. |
Description
Ensembl ID | ENSG00000136381 | Gene ID | 3658 | Accession | 6115 |
Symbol | IREB2 | Alias | ACO3;IRP2;IRP2AD;NDCAMA;IRE-BP2;IRE-BP2 | Full Name | iron responsive element binding protein 2 |
Status | Confidence | Length | 64023 bases | Strand | Plus strand |
Position | 15 : 78437431 - 78501453 | RNA binding domain | Aconitase , Aconitase_C | ||
Summary | The protein encoded by this gene is an RNA-binding protein that acts to regulate iron levels in the cells by regulating the translation and stability of mRNAs that affect iron homeostasis under conditions when iron is depleted. When iron levels are low, this protein binds to iron-responsive elements (IRES), stem-loop structures located either in the 5' or 3' UTRs. Binding to the 5' UTR represses translation, while binding to the 3' UTR inhibits mRNA degradation. When iron is found in the cell, this protein is degraded in a F-box and leucine rich repeat protein 5-dependent manner. Variants in this gene have been associated with lung cancer and chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017] |
RNA binding domains (RBDs)
Protein | Domain | Pfam ID | E-value | Domain number |
---|---|---|---|---|
ENSP00000258886 | Aconitase_C | PF00694 | 6.1e-30 | 1 |
ENSP00000258886 | Aconitase | PF00330 | 5.9e-146 | 2 |
ENSP00000258886 | Aconitase | PF00330 | 5.9e-146 | 3 |
ENSP00000453863 | Aconitase_C | PF00694 | 2.4e-14 | 1 |
ENSP00000452938 | Aconitase | PF00330 | 1e-51 | 1 |
ENSP00000452938 | Aconitase | PF00330 | 1e-51 | 2 |
ENSP00000454063 | Aconitase | PF00330 | 4.3e-12 | 1 |
RNA binding proteomes (RBPomes)
Pubmed ID | Full Name | Cell | Author | Time | Doi |
---|
Literatures on RNA binding capacity
Pubmed ID | Title | Author | Time | Journal |
---|---|---|---|---|
35599631 | MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2. | Hongwei Fan | 2022-05-01 | Bioengineered |
33155665 | Regulation of ferroptosis by non‑coding RNAs in the development and treatment of cancer (Review). | Yajun Luo | 2021-01-01 | Oncology reports |
31297598 | MicroRNAs as modulators of longevity and the aging process. | E Holly Kinser | 2020-03-01 | Human genetics |
36408273 | Relationship between miRNA and ferroptosis in tumors. | Shang-Ming Dai | 2022-01-01 | Frontiers in pharmacology |
28287180 | Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. | D Jarrett Morrow | 2017-03-13 | Scientific reports |
31696517 | Transcriptome-wide association study reveals candidate causal genes for lung cancer. | Yohan Bossé | 2020-04-01 | International journal of cancer |
28181565 | Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci. | Giulia Pintarelli | 2017-02-09 | Scientific reports |
33679722 | The Clinical Significance of Iron Overload and Iron Metabolism in Myelodysplastic Syndrome and Acute Myeloid Leukemia. | Sarah Weber | 2020-01-01 | Frontiers in immunology |
28453699 | MicroRNA-related genetic variants in iron regulatory genes, dietary iron intake, microRNAs and lung cancer risk. | L Zhang | 2017-05-01 | Annals of oncology : official journal of the European Society for Medical Oncology |
Transcripts
Name | Transcript ID | bp | Protein | Translation ID |
---|---|---|---|---|
IREB2-210 | ENST00000560840 | 558 | 38aa | ENSP00000453172 |
IREB2-205 | ENST00000559215 | 572 | 46aa | ENSP00000453532 |
IREB2-201 | ENST00000258886 | 6324 | 963aa | ENSP00000258886 |
IREB2-202 | ENST00000558525 | 865 | 51aa | ENSP00000453058 |
IREB2-208 | ENST00000560440 | 4396 | 343aa | ENSP00000452938 |
IREB2-203 | ENST00000558570 | 2917 | 220aa | ENSP00000454063 |
IREB2-209 | ENST00000560454 | 545 | No protein | - |
IREB2-206 | ENST00000559427 | 608 | No protein | - |
IREB2-207 | ENST00000559676 | 973 | No protein | - |
IREB2-204 | ENST00000559091 | 268 | 89aa | ENSP00000453863 |
Phenotypes
ensgID | Trait | pValue | Pubmed ID |
---|---|---|---|
34342 | Smoking | 1.1700000E-008 | - |
59017 | Airway Obstruction | 1.8460000E-006 | 22837378 |
59038 | Airway Obstruction | 1.8030000E-006 | 22837378 |
59039 | Airway Obstruction | 1.7910000E-006 | 22837378 |
59040 | Airway Obstruction | 1.9950000E-006 | 22837378 |
59041 | Airway Obstruction | 1.7410000E-006 | 22837378 |
60940 | Bronchodilator Agents | 8E-8 | 26634245 |
60941 | Forced Expiratory Volume | 8E-8 | 26634245 |
61053 | Bronchodilator Agents | 7E-8 | 26634245 |
61054 | Lung Volume Measurements | 7E-8 | 26634245 |
61795 | Bronchodilator Agents | 1E-7 | 26634245 |
61796 | Lung Volume Measurements | 1E-7 | 26634245 |
62161 | Bronchodilator Agents | 8E-8 | 26634245 |
62162 | Lung Volume Measurements | 8E-8 | 26634245 |
62350 | Bronchodilator Agents | 5E-6 | 26634245 |
62351 | Lung Volume Measurements | 5E-6 | 26634245 |
62562 | Bronchodilator Agents | 3E-10 | 26634245 |
62563 | Lung Volume Measurements | 3E-10 | 26634245 |
62988 | Bronchodilator Agents | 2E-10 | 26634245 |
62989 | Lung Volume Measurements | 2E-10 | 26634245 |
63378 | Bronchodilator Agents | 4E-7 | 26634245 |
63379 | Forced Expiratory Volume | 4E-7 | 26634245 |
63705 | Bronchodilator Agents | 4E-9 | 26634245 |
63706 | Forced Expiratory Volume | 4E-9 | 26634245 |
63753 | Bronchodilator Agents | 2E-7 | 26634245 |
63754 | Forced Expiratory Volume | 2E-7 | 26634245 |
64090 | Bronchodilator Agents | 2E-6 | 26634245 |
64091 | Lung Volume Measurements | 2E-6 | 26634245 |
64092 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
64440 | Bronchodilator Agents | 1E-6 | 26634245 |
64441 | Forced Expiratory Volume | 1E-6 | 26634245 |
64442 | Pulmonary Disease, Chronic Obstructive | 1E-6 | 26634245 |
64465 | Bronchodilator Agents | 1E-7 | 26634245 |
64466 | Forced Expiratory Volume | 1E-7 | 26634245 |
64561 | Bronchodilator Agents | 8E-10 | 26634245 |
64562 | Forced Expiratory Volume | 8E-10 | 26634245 |
64691 | Bronchodilator Agents | 3E-12 | 26634245 |
64692 | Forced Expiratory Volume | 3E-12 | 26634245 |
64789 | Pulmonary Disease, Chronic Obstructive | 1E-6 | 22080838 |
65170 | Bronchodilator Agents | 1E-6 | 26634245 |
65171 | Lung Volume Measurements | 1E-6 | 26634245 |
65172 | Pulmonary Disease, Chronic Obstructive | 1E-6 | 26634245 |
65364 | Bronchodilator Agents | 1E-12 | 26634245 |
65365 | Lung Volume Measurements | 1E-12 | 26634245 |
65680 | Bronchodilator Agents | 1E-8 | 26634245 |
65681 | Forced Expiratory Volume | 1E-8 | 26634245 |
65846 | Bronchodilator Agents | 6E-8 | 26634245 |
65847 | Lung Volume Measurements | 6E-8 | 26634245 |
66282 | Bronchodilator Agents | 3E-6 | 26634245 |
66283 | Lung Volume Measurements | 3E-6 | 26634245 |
66725 | Bronchodilator Agents | 2E-12 | 26634245 |
66726 | Forced Expiratory Volume | 2E-12 | 26634245 |
66741 | Bronchodilator Agents | 8E-7 | 26634245 |
66742 | Forced Expiratory Volume | 8E-7 | 26634245 |
66779 | Bronchodilator Agents | 1E-8 | 26634245 |
66780 | Lung Volume Measurements | 1E-8 | 26634245 |
66840 | Bronchodilator Agents | 9E-8 | 26634245 |
66841 | Lung Volume Measurements | 9E-8 | 26634245 |
66887 | Bronchodilator Agents | 2E-13 | 26634245 |
66888 | Forced Expiratory Volume | 2E-13 | 26634245 |
67194 | Bronchodilator Agents | 2E-7 | 26634245 |
67195 | Forced Expiratory Volume | 2E-7 | 26634245 |
67323 | Bronchodilator Agents | 2E-12 | 26634245 |
67324 | Lung Volume Measurements | 2E-12 | 26634245 |
67353 | Bronchodilator Agents | 1E-13 | 26634245 |
67354 | Forced Expiratory Volume | 1E-13 | 26634245 |
67500 | Forced Expiratory Volume | 1E-7 | 26634245 |
67725 | Bronchodilator Agents | 5E-9 | 26634245 |
67726 | Forced Expiratory Volume | 5E-9 | 26634245 |
67902 | Bronchodilator Agents | 2E-13 | 26634245 |
67903 | Forced Expiratory Volume | 2E-13 | 26634245 |
68201 | Bronchodilator Agents | 6E-8 | 26634245 |
68202 | Lung Volume Measurements | 6E-8 | 26634245 |
68269 | Bronchodilator Agents | 2E-6 | 26634245 |
68270 | Forced Expiratory Volume | 2E-6 | 26634245 |
68271 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
68496 | Bronchodilator Agents | 2E-14 | 26634245 |
68497 | Forced Expiratory Volume | 2E-14 | 26634245 |
69059 | Bronchodilator Agents | 5E-7 | 26634245 |
69060 | Forced Expiratory Volume | 5E-7 | 26634245 |
69074 | Bronchodilator Agents | 2E-12 | 26634245 |
69075 | Forced Expiratory Volume | 2E-12 | 26634245 |
69468 | Bronchodilator Agents | 9E-9 | 26634245 |
69469 | Forced Expiratory Volume | 9E-9 | 26634245 |
69627 | Bronchodilator Agents | 4E-6 | 26634245 |
69628 | Forced Expiratory Volume | 4E-6 | 26634245 |
69629 | Pulmonary Disease, Chronic Obstructive | 4E-6 | 26634245 |
69714 | Bronchodilator Agents | 4E-9 | 26634245 |
69715 | Lung Volume Measurements | 4E-9 | 26634245 |
69810 | Bronchodilator Agents | 2E-6 | 26634245 |
69811 | Lung Volume Measurements | 2E-6 | 26634245 |
69812 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
70349 | Bronchodilator Agents | 6E-7 | 26634245 |
70350 | Forced Expiratory Volume | 6E-7 | 26634245 |
70908 | Bronchodilator Agents | 7E-8 | 26634245 |
70909 | Lung Volume Measurements | 7E-8 | 26634245 |
71281 | Bronchodilator Agents | 6E-9 | 26634245 |
71282 | Lung Volume Measurements | 6E-9 | 26634245 |
71402 | Bronchodilator Agents | 5E-8 | 26634245 |
71403 | Lung Volume Measurements | 5E-8 | 26634245 |
71572 | Bronchodilator Agents | 4E-6 | 26634245 |
71573 | Forced Expiratory Volume | 4E-6 | 26634245 |
71574 | Pulmonary Disease, Chronic Obstructive | 4E-6 | 26634245 |
71954 | Bronchodilator Agents | 1E-7 | 26634245 |
71955 | Lung Volume Measurements | 1E-7 | 26634245 |
72920 | Bronchodilator Agents | 7E-7 | 26634245 |
72921 | Forced Expiratory Volume | 7E-7 | 26634245 |
73061 | Bronchodilator Agents | 4E-9 | 26634245 |
73062 | Forced Expiratory Volume | 4E-9 | 26634245 |
73122 | Bronchodilator Agents | 2E-6 | 26634245 |
73123 | Lung Volume Measurements | 2E-6 | 26634245 |
73141 | Bronchodilator Agents | 4E-8 | 26634245 |
73142 | Lung Volume Measurements | 4E-8 | 26634245 |
73418 | Bronchodilator Agents | 2E-6 | 26634245 |
73419 | Lung Volume Measurements | 2E-6 | 26634245 |
73420 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
73785 | Bronchodilator Agents | 5E-13 | 26634245 |
73786 | Lung Volume Measurements | 5E-13 | 26634245 |
74471 | Bronchodilator Agents | 2E-6 | 26634245 |
74472 | Lung Volume Measurements | 2E-6 | 26634245 |
74473 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
74724 | Bronchodilator Agents | 4E-8 | 26634245 |
74725 | Forced Expiratory Volume | 4E-8 | 26634245 |
74923 | Bronchodilator Agents | 5E-7 | 26634245 |
74924 | Forced Expiratory Volume | 5E-7 | 26634245 |
75025 | Bronchodilator Agents | 3E-10 | 26634245 |
75026 | Lung Volume Measurements | 3E-10 | 26634245 |
75192 | Bronchodilator Agents | 5E-6 | 26634245 |
75193 | Lung Volume Measurements | 5E-6 | 26634245 |
75575 | Bronchodilator Agents | 4E-9 | 26634245 |
75576 | Lung Volume Measurements | 4E-9 | 26634245 |
75654 | Forced Expiratory Volume | 1E-7 | 26634245 |
75983 | Bronchodilator Agents | 7E-7 | 26634245 |
75984 | Forced Expiratory Volume | 7E-7 | 26634245 |
75985 | Pulmonary Disease, Chronic Obstructive | 7E-7 | 26634245 |
76630 | Bronchodilator Agents | 2E-7 | 26634245 |
76631 | Forced Expiratory Volume | 2E-7 | 26634245 |
76659 | Bronchodilator Agents | 7E-9 | 26634245 |
76660 | Forced Expiratory Volume | 7E-9 | 26634245 |
76780 | Bronchodilator Agents | 3E-6 | 26634245 |
76781 | Lung Volume Measurements | 3E-6 | 26634245 |
76782 | Pulmonary Disease, Chronic Obstructive | 3E-6 | 26634245 |
77413 | Bronchodilator Agents | 4E-6 | 26634245 |
77414 | Lung Volume Measurements | 4E-6 | 26634245 |
77694 | Bronchodilator Agents | 8E-9 | 26634245 |
77695 | Forced Expiratory Volume | 8E-9 | 26634245 |
78681 | Pulmonary Disease, Chronic Obstructive | 2E-8 | 20173748 |
79276 | Bronchodilator Agents | 2E-7 | 26634245 |
79277 | Lung Volume Measurements | 2E-7 | 26634245 |
79283 | Bronchodilator Agents | 2E-7 | 26634245 |
79284 | Forced Expiratory Volume | 2E-7 | 26634245 |
79438 | Bronchodilator Agents | 7E-10 | 26634245 |
79439 | Lung Volume Measurements | 7E-10 | 26634245 |
80850 | Bronchodilator Agents | 2E-6 | 26634245 |
80851 | Lung Volume Measurements | 2E-6 | 26634245 |
80852 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
81185 | Bronchodilator Agents | 2E-12 | 26634245 |
81186 | Lung Volume Measurements | 2E-12 | 26634245 |
81382 | Forced Expiratory Volume | 7E-8 | 26634245 |
81496 | Bronchodilator Agents | 1E-10 | 26634245 |
81497 | Forced Expiratory Volume | 1E-10 | 26634245 |
82199 | Bronchodilator Agents | 8E-7 | 26634245 |
82200 | Forced Expiratory Volume | 8E-7 | 26634245 |
82204 | Bronchodilator Agents | 2E-10 | 26634245 |
82205 | Lung Volume Measurements | 2E-10 | 26634245 |
82270 | Bronchodilator Agents | 3E-12 | 26634245 |
82271 | Forced Expiratory Volume | 3E-12 | 26634245 |
82465 | Bronchodilator Agents | 6E-9 | 26634245 |
82466 | Forced Expiratory Volume | 6E-9 | 26634245 |
82490 | Bronchodilator Agents | 3E-12 | 26634245 |
82491 | Forced Expiratory Volume | 3E-12 | 26634245 |
82927 | Bronchodilator Agents | 5E-9 | 26634245 |
82928 | Forced Expiratory Volume | 5E-9 | 26634245 |
83072 | Bronchodilator Agents | 4E-6 | 26634245 |
83073 | Lung Volume Measurements | 4E-6 | 26634245 |
83215 | Bronchodilator Agents | 7E-7 | 26634245 |
83216 | Forced Expiratory Volume | 7E-7 | 26634245 |
83247 | Bronchodilator Agents | 2E-7 | 26634245 |
83248 | Lung Volume Measurements | 2E-7 | 26634245 |
83347 | Bronchodilator Agents | 2E-10 | 26634245 |
83348 | Lung Volume Measurements | 2E-10 | 26634245 |
84035 | Bronchodilator Agents | 9E-7 | 26634245 |
84036 | Forced Expiratory Volume | 9E-7 | 26634245 |
84378 | Bronchodilator Agents | 5E-6 | 26634245 |
84379 | Lung Volume Measurements | 5E-6 | 26634245 |
84506 | Bronchodilator Agents | 2E-12 | 26634245 |
84507 | Forced Expiratory Volume | 2E-12 | 26634245 |
84734 | Bronchodilator Agents | 6E-7 | 26634245 |
84735 | Forced Expiratory Volume | 6E-7 | 26634245 |
84765 | Bronchodilator Agents | 3E-6 | 26634245 |
84766 | Lung Volume Measurements | 3E-6 | 26634245 |
85026 | Bronchodilator Agents | 3E-12 | 26634245 |
85027 | Forced Expiratory Volume | 3E-12 | 26634245 |
85169 | Longevity | 5E-6 | 27015805 |
85218 | Bronchodilator Agents | 5E-6 | 26634245 |
85219 | Forced Expiratory Volume | 5E-6 | 26634245 |
85220 | Pulmonary Disease, Chronic Obstructive | 5E-6 | 26634245 |
85576 | Bronchodilator Agents | 2E-6 | 26634245 |
85577 | Lung Volume Measurements | 2E-6 | 26634245 |
85578 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
85710 | Bronchodilator Agents | 6E-7 | 26634245 |
85711 | Forced Expiratory Volume | 6E-7 | 26634245 |
86080 | Pulmonary Disease, Chronic Obstructive | 5E-8 | 25241909 |
86274 | Bronchodilator Agents | 2E-13 | 26634245 |
86275 | Forced Expiratory Volume | 2E-13 | 26634245 |
86301 | Bronchodilator Agents | 1E-12 | 26634245 |
86302 | Forced Expiratory Volume | 1E-12 | 26634245 |
86417 | Bronchodilator Agents | 9E-11 | 26634245 |
86418 | Forced Expiratory Volume | 9E-11 | 26634245 |
86518 | Bronchodilator Agents | 1E-8 | 26634245 |
86519 | Forced Expiratory Volume | 1E-8 | 26634245 |
87160 | Bronchodilator Agents | 2E-7 | 26634245 |
87161 | Forced Expiratory Volume | 2E-7 | 26634245 |
87275 | Bronchodilator Agents | 8E-11 | 26634245 |
87276 | Forced Expiratory Volume | 8E-11 | 26634245 |
87774 | Bronchodilator Agents | 8E-13 | 26634245 |
87775 | Lung Volume Measurements | 8E-13 | 26634245 |
87792 | Bronchodilator Agents | 2E-6 | 26634245 |
87793 | Lung Volume Measurements | 2E-6 | 26634245 |
87794 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
87964 | Bronchodilator Agents | 5E-6 | 26634245 |
87965 | Lung Volume Measurements | 5E-6 | 26634245 |
88118 | Bronchodilator Agents | 9E-8 | 26634245 |
88119 | Lung Volume Measurements | 9E-8 | 26634245 |
88150 | Bronchodilator Agents | 2E-6 | 26634245 |
88151 | Lung Volume Measurements | 2E-6 | 26634245 |
88299 | Bronchodilator Agents | 2E-6 | 26634245 |
88300 | Lung Volume Measurements | 2E-6 | 26634245 |
88301 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
88389 | Bronchodilator Agents | 9E-7 | 26634245 |
88390 | Forced Expiratory Volume | 9E-7 | 26634245 |
88457 | Bronchodilator Agents | 2E-7 | 26634245 |
88458 | Forced Expiratory Volume | 2E-7 | 26634245 |
88492 | Bronchodilator Agents | 7E-8 | 26634245 |
88493 | Lung Volume Measurements | 7E-8 | 26634245 |
88546 | Bronchodilator Agents | 7E-9 | 26634245 |
88547 | Forced Expiratory Volume | 7E-9 | 26634245 |
88729 | Bronchodilator Agents | 4E-7 | 26634245 |
88730 | Forced Expiratory Volume | 4E-7 | 26634245 |
88925 | Bronchodilator Agents | 4E-7 | 26634245 |
88926 | Lung Volume Measurements | 4E-7 | 26634245 |
89232 | Bronchodilator Agents | 4E-12 | 26634245 |
89233 | Forced Expiratory Volume | 4E-12 | 26634245 |
89492 | Bronchodilator Agents | 7E-10 | 26634245 |
89493 | Lung Volume Measurements | 7E-10 | 26634245 |
90042 | Bronchodilator Agents | 1E-7 | 26634245 |
90043 | Lung Volume Measurements | 1E-7 | 26634245 |
90534 | Bronchodilator Agents | 2E-6 | 26634245 |
90535 | Lung Volume Measurements | 2E-6 | 26634245 |
90536 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
90900 | Bronchodilator Agents | 2E-6 | 26634245 |
90901 | Lung Volume Measurements | 2E-6 | 26634245 |
90902 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
91024 | Bronchodilator Agents | 4E-6 | 26634245 |
91025 | Lung Volume Measurements | 4E-6 | 26634245 |
91148 | Bronchodilator Agents | 1E-7 | 26634245 |
91149 | Lung Volume Measurements | 1E-7 | 26634245 |
91233 | Bronchodilator Agents | 6E-9 | 26634245 |
91234 | Forced Expiratory Volume | 6E-9 | 26634245 |
91551 | Bronchodilator Agents | 2E-12 | 26634245 |
91552 | Lung Volume Measurements | 2E-12 | 26634245 |
91924 | Bronchodilator Agents | 4E-6 | 26634245 |
91925 | Forced Expiratory Volume | 4E-6 | 26634245 |
91926 | Pulmonary Disease, Chronic Obstructive | 4E-6 | 26634245 |
92144 | Bronchodilator Agents | 1E-9 | 26634245 |
92145 | Forced Expiratory Volume | 1E-9 | 26634245 |
92490 | Bronchodilator Agents | 3E-12 | 26634245 |
92491 | Forced Expiratory Volume | 3E-12 | 26634245 |
93156 | Bronchodilator Agents | 2E-6 | 26634245 |
93157 | Lung Volume Measurements | 2E-6 | 26634245 |
93324 | Bronchodilator Agents | 3E-6 | 26634245 |
93325 | Lung Volume Measurements | 3E-6 | 26634245 |
94151 | Bronchodilator Agents | 3E-12 | 26634245 |
94152 | Forced Expiratory Volume | 3E-12 | 26634245 |
94203 | Bronchodilator Agents | 2E-6 | 26634245 |
94204 | Lung Volume Measurements | 2E-6 | 26634245 |
94205 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
94722 | Bronchodilator Agents | 2E-10 | 26634245 |
94723 | Lung Volume Measurements | 2E-10 | 26634245 |
95109 | Bronchodilator Agents | 3E-6 | 26634245 |
95110 | Lung Volume Measurements | 3E-6 | 26634245 |
95955 | Bronchodilator Agents | 3E-10 | 26634245 |
95956 | Lung Volume Measurements | 3E-10 | 26634245 |
96573 | Bronchodilator Agents | 5E-7 | 26634245 |
96574 | Forced Expiratory Volume | 5E-7 | 26634245 |
96759 | Bronchodilator Agents | 7E-8 | 26634245 |
96760 | Lung Volume Measurements | 7E-8 | 26634245 |
97199 | Bronchodilator Agents | 1E-12 | 26634245 |
97200 | Forced Expiratory Volume | 1E-12 | 26634245 |
97318 | Bronchodilator Agents | 2E-6 | 26634245 |
97319 | Forced Expiratory Volume | 2E-6 | 26634245 |
97320 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
97766 | Bronchodilator Agents | 2E-6 | 26634245 |
97767 | Lung Volume Measurements | 2E-6 | 26634245 |
97768 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
98023 | Bronchodilator Agents | 6E-9 | 26634245 |
98024 | Forced Expiratory Volume | 6E-9 | 26634245 |
98035 | Forced Expiratory Volume | 1E-7 | 26634245 |
98084 | Bronchodilator Agents | 4E-9 | 26634245 |
98085 | Forced Expiratory Volume | 4E-9 | 26634245 |
98196 | Bronchodilator Agents | 2E-6 | 26634245 |
98197 | Lung Volume Measurements | 2E-6 | 26634245 |
98198 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
98259 | Bronchodilator Agents | 9E-7 | 26634245 |
98260 | Forced Expiratory Volume | 9E-7 | 26634245 |
98417 | Bronchodilator Agents | 7E-7 | 26634245 |
98418 | Forced Expiratory Volume | 7E-7 | 26634245 |
98422 | Bronchodilator Agents | 2E-6 | 26634245 |
98423 | Lung Volume Measurements | 2E-6 | 26634245 |
98424 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
98458 | Bronchodilator Agents | 2E-12 | 26634245 |
98459 | Lung Volume Measurements | 2E-12 | 26634245 |
98643 | Bronchodilator Agents | 3E-12 | 26634245 |
98644 | Forced Expiratory Volume | 3E-12 | 26634245 |
98888 | Bronchodilator Agents | 5E-6 | 26634245 |
98889 | Lung Volume Measurements | 5E-6 | 26634245 |
98959 | Bronchodilator Agents | 2E-6 | 26634245 |
98960 | Lung Volume Measurements | 2E-6 | 26634245 |
98961 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
98973 | Bronchodilator Agents | 7E-9 | 26634245 |
98974 | Forced Expiratory Volume | 7E-9 | 26634245 |
99035 | Bronchodilator Agents | 3E-10 | 26634245 |
99036 | Lung Volume Measurements | 3E-10 | 26634245 |
99650 | Bronchodilator Agents | 5E-7 | 26634245 |
99651 | Forced Expiratory Volume | 5E-7 | 26634245 |
99670 | Bronchodilator Agents | 2E-6 | 26634245 |
99671 | Lung Volume Measurements | 2E-6 | 26634245 |
99672 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
99684 | Bronchodilator Agents | 4E-10 | 26634245 |
99685 | Lung Volume Measurements | 4E-10 | 26634245 |
100036 | Bronchodilator Agents | 4E-6 | 26634245 |
100037 | Lung Volume Measurements | 4E-6 | 26634245 |
100078 | Bronchodilator Agents | 3E-13 | 26634245 |
100079 | Forced Expiratory Volume | 3E-13 | 26634245 |
100245 | Bronchodilator Agents | 4E-6 | 26634245 |
100246 | Lung Volume Measurements | 4E-6 | 26634245 |
100556 | Bronchodilator Agents | 3E-12 | 26634245 |
100557 | Lung Volume Measurements | 3E-12 | 26634245 |
100732 | Bronchodilator Agents | 1E-7 | 26634245 |
100733 | Forced Expiratory Volume | 1E-7 | 26634245 |
100827 | Bronchodilator Agents | 6E-9 | 26634245 |
100828 | Forced Expiratory Volume | 6E-9 | 26634245 |
101279 | Bronchodilator Agents | 7E-7 | 26634245 |
101280 | Forced Expiratory Volume | 7E-7 | 26634245 |
101323 | Bronchodilator Agents | 6E-8 | 26634245 |
101324 | Lung Volume Measurements | 6E-8 | 26634245 |
101728 | Bronchodilator Agents | 7E-9 | 26634245 |
101729 | Forced Expiratory Volume | 7E-9 | 26634245 |
101918 | Bronchodilator Agents | 9E-7 | 26634245 |
101919 | Forced Expiratory Volume | 9E-7 | 26634245 |
102807 | Bronchodilator Agents | 1E-9 | 26634245 |
102808 | Lung Volume Measurements | 1E-9 | 26634245 |
102861 | Bronchodilator Agents | 2E-6 | 26634245 |
102862 | Forced Expiratory Volume | 2E-6 | 26634245 |
102863 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
103013 | Bronchodilator Agents | 3E-6 | 26634245 |
103014 | Lung Volume Measurements | 3E-6 | 26634245 |
103015 | Pulmonary Disease, Chronic Obstructive | 3E-6 | 26634245 |
103209 | Bronchodilator Agents | 1E-13 | 26634245 |
103210 | Forced Expiratory Volume | 1E-13 | 26634245 |
103853 | Bronchodilator Agents | 1E-6 | 26634245 |
103854 | Lung Volume Measurements | 1E-6 | 26634245 |
103855 | Pulmonary Disease, Chronic Obstructive | 1E-6 | 26634245 |
104186 | Bronchodilator Agents | 3E-13 | 26634245 |
104187 | Forced Expiratory Volume | 3E-13 | 26634245 |
104188 | Bronchodilator Agents | 2E-7 | 26634245 |
104189 | Forced Expiratory Volume | 2E-7 | 26634245 |
104616 | Bronchodilator Agents | 2E-7 | 26634245 |
104617 | Forced Expiratory Volume | 2E-7 | 26634245 |
105118 | Pulmonary Artery | 2E-8 | 25101718 |
105119 | Pulmonary Disease, Chronic Obstructive | 2E-8 | 25101718 |
105220 | Bronchodilator Agents | 1E-11 | 26634245 |
105221 | Lung Volume Measurements | 1E-11 | 26634245 |
105905 | Bronchodilator Agents | 4E-7 | 26634245 |
105906 | Forced Expiratory Volume | 4E-7 | 26634245 |
106043 | Bronchodilator Agents | 2E-6 | 26634245 |
106044 | Lung Volume Measurements | 2E-6 | 26634245 |
106045 | Pulmonary Disease, Chronic Obstructive | 2E-6 | 26634245 |
106757 | Bronchodilator Agents | 3E-6 | 26634245 |
106758 | Lung Volume Measurements | 3E-6 | 26634245 |
GWAS
ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
---|
Protein-Protein Interaction (PPI)
Paralogs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000136381 | homo_sapiens | ENSP00000216254 | 46.0256 | 27.5641 | homo_sapiens | ENSP00000258886 | 37.2793 | 22.3261 |
ENSG00000136381 | homo_sapiens | ENSP00000309477 | 79.64 | 61.1924 | homo_sapiens | ENSP00000258886 | 73.5202 | 56.4901 |
Orthologs
Ensembl ID | Source | Target | ||||||
---|---|---|---|---|---|---|---|---|
Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.4808 | nomascus_leucogenys | ENSNLEP00000010533 | 99.6888 | 99.3776 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.5846 | 99.5846 | pan_paniscus | ENSPPAP00000032132 | 99.5846 | 99.5846 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.8962 | 99.5846 | pongo_abelii | ENSPPYP00000007600 | 99.7925 | 99.4813 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.5846 | 99.5846 | pan_troglodytes | ENSPTRP00000012550 | 99.5846 | 99.5846 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.6885 | gorilla_gorilla | ENSGGOP00000015278 | 99.7923 | 99.6885 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.7695 | 88.162 | ornithorhynchus_anatinus | ENSOANP00000020880 | 93.5751 | 87.9793 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 94.081 | 88.9927 | sarcophilus_harrisii | ENSSHAP00000034200 | 85.3107 | 80.6968 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 65.3167 | 62.0976 | notamacropus_eugenii | ENSMEUP00000001497 | 64.9793 | 61.7769 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.6656 | 91.2773 | choloepus_hoffmanni | ENSCHOP00000003640 | 94.5493 | 92.1384 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.7695 | 91.3811 | dasypus_novemcinctus | ENSDNOP00000007462 | 96.9925 | 94.522 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 83.0737 | 77.3624 | erinaceus_europaeus | ENSEEUP00000007319 | 90.4977 | 84.276 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 71.6511 | 69.7819 | echinops_telfairi | ENSETEP00000010312 | 71.8002 | 69.9272 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.9616 | 97.8193 | callithrix_jacchus | ENSCJAP00000019077 | 98.8589 | 97.7178 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.2731 | cercocebus_atys | ENSCATP00000019342 | 99.6888 | 99.1701 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.6885 | 99.1693 | macaca_fascicularis | ENSMFAP00000044607 | 99.5851 | 99.0664 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.2731 | macaca_mulatta | ENSMMUP00000030902 | 99.6888 | 99.1701 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.9886 | 95.9502 | macaca_nemestrina | ENSMNEP00000032962 | 98.7315 | 97.6744 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.2731 | papio_anubis | ENSPANP00000045574 | 89.8131 | 89.3458 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.2731 | mandrillus_leucophaeus | ENSMLEP00000013758 | 99.6888 | 99.1701 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 86.9159 | 84.3198 | tursiops_truncatus | ENSTTRP00000000658 | 87.0062 | 84.4075 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.7965 | 87.8505 | vulpes_vulpes | ENSVVUP00000010574 | 97.5717 | 93.3775 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.677 | 93.6656 | mus_spretus | MGP_SPRETEiJ_P0091525 | 96.677 | 93.6656 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.677 | 94.4964 | equus_asinus | ENSEASP00005022929 | 97.2832 | 95.0888 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.1578 | capra_hircus | ENSCHIP00000027064 | 98.7552 | 96.0581 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.5078 | 95.0156 | loxodonta_africana | ENSLAFP00000010736 | 97.6091 | 95.1143 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.8463 | 92.5234 | panthera_leo | ENSPLOP00000024521 | 95.7469 | 92.4274 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.9886 | 92.9387 | ailuropoda_melanoleuca | ENSAMEP00000013343 | 94.7262 | 90.7708 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.5888 | 87.8505 | bos_indicus_hybrid | ENSBIXP00005031998 | 90.9278 | 87.2165 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.054 | 92.0042 | oryctolagus_cuniculus | ENSOCUP00000008534 | 96.7573 | 92.6778 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.3001 | 95.0156 | equus_caballus | ENSECAP00000026626 | 97.0984 | 94.8186 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.5732 | 92.2118 | canis_lupus_familiaris | ENSCAFP00845018608 | 96.473 | 92.1162 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.9502 | 92.5234 | panthera_pardus | ENSPPRP00000008290 | 95.8506 | 92.4274 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 88.785 | 86.9159 | marmota_marmota_marmota | ENSMMMP00000001354 | 98.0505 | 95.9862 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 50.675 | 48.9097 | balaenoptera_musculus | ENSBMSP00010018911 | 96.063 | 92.7165 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 22.2222 | 21.08 | balaenoptera_musculus | ENSBMSP00010018926 | 96.8326 | 91.8552 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 83.8006 | 80.3738 | cavia_porcellus | ENSCPOP00000012532 | 96.1859 | 92.2527 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.9502 | 92.5234 | felis_catus | ENSFCAP00000001777 | 95.8506 | 92.4274 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 92.0042 | 88.785 | ursus_americanus | ENSUAMP00000022812 | 97.7925 | 94.3709 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 24.5068 | 21.4953 | monodelphis_domestica | ENSMODP00000014741 | 83.6879 | 73.4043 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 96.1578 | bison_bison_bison | ENSBBBP00000001419 | 98.9627 | 96.0581 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.7539 | 96.054 | monodon_monoceros | ENSMMNP00015015206 | 98.6515 | 95.9544 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.1578 | sus_scrofa | ENSSSCP00000001913 | 98.8577 | 96.1578 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.7809 | microcebus_murinus | ENSMICP00000018745 | 98.7552 | 96.6805 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.054 | 92.0042 | octodon_degus | ENSODEP00000021747 | 96.054 | 92.0042 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 90.758 | 87.0197 | jaculus_jaculus | ENSJJAP00000018545 | 95.5191 | 91.5847 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.1693 | 96.5732 | ovis_aries_rambouillet | ENSOARP00020024499 | 99.0664 | 96.473 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 92.9387 | 89.5119 | ursus_maritimus | ENSUMAP00000015806 | 90.9553 | 87.6016 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 90.758 | 86.189 | ochotona_princeps | ENSOPRP00000000311 | 90.8524 | 86.2786 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.6501 | 95.9502 | delphinapterus_leucas | ENSDLEP00000000369 | 98.5477 | 95.8506 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.5348 | 92.8349 | physeter_catodon | ENSPCTP00005028584 | 97.6645 | 94.9045 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.7809 | 93.5618 | mus_caroli | MGP_CAROLIEiJ_P0087920 | 96.7809 | 93.5618 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.677 | 93.6656 | mus_musculus | ENSMUSP00000034843 | 96.677 | 93.6656 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 85.0467 | 80.3738 | dipodomys_ordii | ENSDORP00000013488 | 92.126 | 87.0641 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.7425 | 92.0042 | mustela_putorius_furo | ENSMPUP00000010889 | 91.2871 | 87.7228 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 97.7155 | aotus_nancymaae | ENSANAP00000008027 | 98.9627 | 97.6141 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.5462 | 97.1963 | saimiri_boliviensis_boliviensis | ENSSBOP00000029068 | 98.1386 | 96.7942 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.1963 | 94.1848 | vicugna_pacos | ENSVPAP00000007677 | 98.5263 | 95.4737 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.7923 | 99.3769 | chlorocebus_sabaeus | ENSCSAP00000011013 | 99.6888 | 99.2739 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.1277 | 76.947 | tupaia_belangeri | ENSTBEP00000009463 | 79.0456 | 76.8672 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 21.1838 | 20.2492 | mesocricetus_auratus | ENSMAUP00000023617 | 93.1507 | 89.0411 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.5462 | 95.8463 | phocoena_sinus | ENSPSNP00000000837 | 98.444 | 95.7469 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.054 | camelus_dromedarius | ENSCDRP00005027577 | 98.7552 | 95.9544 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.6501 | 96.8847 | carlito_syrichta | ENSTSYP00000010759 | 98.3437 | 96.5839 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.2233 | 91.9003 | panthera_tigris_altaica | ENSPTIP00000025761 | 82.316 | 79.4434 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.8847 | 93.5618 | rattus_norvegicus | ENSRNOP00000084367 | 92.0118 | 88.856 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.677 | prolemur_simus | ENSPSMP00000000594 | 98.7552 | 96.5768 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.0924 | 93.0426 | microtus_ochrogaster | ENSMOCP00000010574 | 97.0924 | 93.0426 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.5888 | 86.3967 | sorex_araneus | ENSSARP00000001106 | 95.1456 | 89.7519 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.6116 | 93.8733 | peromyscus_maniculatus_bairdii | ENSPEMP00000023034 | 97.6116 | 93.8733 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 96.1578 | bos_mutus | ENSBMUP00000004724 | 98.9627 | 96.0581 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.677 | 93.6656 | mus_spicilegus | ENSMSIP00000004688 | 96.677 | 93.6656 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.3001 | 93.6656 | cricetulus_griseus_chok1gshd | ENSCGRP00001019938 | 97.3001 | 93.6656 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.9969 | 77.3624 | pteropus_vampyrus | ENSPVAP00000013794 | 81.0811 | 77.4428 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 94.1848 | 88.162 | myotis_lucifugus | ENSMLUP00000006198 | 93.5052 | 87.5258 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 94.4964 | 88.785 | vombatus_ursinus | ENSVURP00010016724 | 94.3005 | 88.601 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 97.3001 | 93.4579 | rhinolophus_ferrumequinum | ENSRFEP00010023996 | 97.1992 | 93.361 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 95.5348 | 91.6926 | neovison_vison | ENSNVIP00000012520 | 96.1338 | 92.2675 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 96.2617 | bos_taurus | ENSBTAP00000058582 | 98.9627 | 96.1618 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.6656 | 89.9273 | heterocephalus_glaber_female | ENSHGLP00000000973 | 94.8475 | 91.062 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.8962 | 99.2731 | rhinopithecus_bieti | ENSRBIP00000019739 | 99.7925 | 99.1701 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.7695 | 88.785 | canis_lupus_dingo | ENSCAFP00020027217 | 89.4946 | 84.7374 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.027 | 96.1578 | sciurus_vulgaris | ENSSVLP00005008647 | 98.027 | 96.1578 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 94.3925 | 88.785 | phascolarctos_cinereus | ENSPCIP00000025301 | 94.1969 | 88.601 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.0353 | 80.27 | procavia_capensis | ENSPCAP00000001908 | 82.206 | 80.437 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.2617 | 93.2503 | nannospalax_galili | ENSNGAP00000016695 | 95.9627 | 92.9607 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 96.1578 | bos_grunniens | ENSBGRP00000030375 | 98.9627 | 96.0581 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.3655 | 92.6272 | chinchilla_lanigera | ENSCLAP00000013020 | 96.3655 | 92.6272 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.8577 | 96.1578 | cervus_hanglu_yarkandensis | ENSCHYP00000019043 | 98.7552 | 96.0581 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.4424 | 95.6386 | catagonus_wagneri | ENSCWAP00000015218 | 98.3402 | 95.5394 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.5462 | 96.4694 | ictidomys_tridecemlineatus | ENSSTOP00000008333 | 98.5462 | 96.4694 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.2617 | 93.0426 | otolemur_garnettii | ENSOGAP00000009508 | 95.8635 | 92.6577 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.2731 | 98.3385 | cebus_imitator | ENSCCAP00000006954 | 99.1701 | 98.2365 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 20.3531 | 19.3146 | urocitellus_parryii | ENSUPAP00010030041 | 87.1111 | 82.6667 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.0654 | 96.054 | moschus_moschiferus | ENSMMSP00000028758 | 98.9627 | 95.9544 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 99.8962 | 99.2731 | rhinopithecus_roxellana | ENSRROP00000000434 | 99.7925 | 99.1701 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 96.677 | 93.1464 | mus_pahari | MGP_PahariEiJ_P0023570 | 96.677 | 93.1464 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 98.5462 | 96.7809 | propithecus_coquereli | ENSPCOP00000020039 | 98.444 | 96.6805 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 85.4621 | 73.8318 | callorhinchus_milii | ENSCMIP00000015489 | 85.1086 | 73.5264 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.4507 | 69.3666 | latimeria_chalumnae | ENSLACP00000001317 | 82.2798 | 69.2228 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.9699 | 70.8204 | lepisosteus_oculatus | ENSLOCP00000018513 | 82.0329 | 70.0205 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 65.6282 | clupea_harengus | ENSCHAP00000057623 | 77.6553 | 63.3267 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.1661 | 65.6282 | danio_rerio | ENSDARP00000117448 | 79.2608 | 64.8871 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.3738 | 66.6667 | carassius_auratus | ENSCARP00000119030 | 78.7386 | 65.3103 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.7508 | 65.8359 | carassius_auratus | ENSCARP00000103036 | 77.1859 | 63.7186 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.893 | 66.8744 | carassius_auratus | ENSCARP00000028137 | 79.7339 | 65.9161 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 13.2918 | 10.2804 | carassius_auratus | ENSCARP00000036316 | 59.8131 | 46.2617 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.2046 | 67.9128 | astyanax_mexicanus | ENSAMXP00000009000 | 80.5355 | 67.3532 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.7238 | 66.7705 | ictalurus_punctatus | ENSIPUP00000021937 | 80.3882 | 65.6793 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.2046 | 68.1205 | esox_lucius | ENSELUP00000024927 | 80.37 | 67.4203 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.6199 | 66.7705 | electrophorus_electricus | ENSEEEP00000038508 | 80.9475 | 66.2204 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.1391 | 68.6397 | oncorhynchus_kisutch | ENSOKIP00005110710 | 81.5464 | 68.1443 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 67.4974 | oncorhynchus_mykiss | ENSOMYP00000051233 | 77.1825 | 64.4841 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.893 | 67.6012 | salmo_salar | ENSSSAP00000043770 | 81.7419 | 68.3106 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.243 | 68.5358 | salmo_trutta | ENSSTUP00000089795 | 81.9028 | 68.2523 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.5431 | 64.9014 | gadus_morhua | ENSGMOP00000049593 | 74.5136 | 60.7977 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.1661 | 67.8089 | fundulus_heteroclitus | ENSFHEP00000031752 | 77.2773 | 65.3654 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 67.2897 | poecilia_reticulata | ENSPREP00000019075 | 78.4631 | 65.5207 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.9585 | 66.9782 | xiphophorus_maculatus | ENSXMAP00000002201 | 77.9352 | 65.2834 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 67.8089 | oryzias_latipes | ENSORLP00000002417 | 73.5294 | 61.9545 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 68.0166 | cyclopterus_lumpus | ENSCLMP00005018552 | 80.1858 | 67.5955 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 68.432 | oreochromis_niloticus | ENSONIP00000016157 | 80.2062 | 67.9381 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 68.1205 | haplochromis_burtoni | ENSHBUP00000025249 | 80.1653 | 67.7686 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 68.2243 | astatotilapia_calliptera | ENSACLP00000036489 | 80.2686 | 67.8719 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.1007 | 68.6397 | sparus_aurata | ENSSAUP00010027407 | 80.1848 | 67.8645 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.1661 | 67.7051 | lates_calcarifer | ENSLCAP00010012310 | 79.8345 | 67.425 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.7508 | 67.082 | xenopus_tropicalis | ENSXETP00000091257 | 78.0488 | 65.6504 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.0426 | 85.4621 | chrysemys_picta_bellii | ENSCPBP00000034766 | 90.1408 | 82.7968 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.9003 | 83.6968 | sphenodon_punctatus | ENSSPUP00000008115 | 91.7098 | 83.5233 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 88.8889 | 78.297 | laticauda_laticaudata | ENSLLTP00000008252 | 88.7967 | 78.2158 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 89.0966 | 78.4008 | notechis_scutatus | ENSNSUP00000027446 | 88.8199 | 78.1573 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 87.1236 | 76.947 | pseudonaja_textilis | ENSPTXP00000014522 | 85.6997 | 75.6895 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.3811 | 82.5545 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000019949 | 88.5312 | 79.9799 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 90.9657 | 82.0353 | gallus_gallus | ENSGALP00010036029 | 87.6877 | 79.0791 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 90.0312 | 80.893 | meleagris_gallopavo | ENSMGAP00000003477 | 87.5758 | 78.6869 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 89.5119 | 80.5815 | serinus_canaria | ENSSCAP00000017320 | 89.3264 | 80.4145 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 89.6158 | 80.893 | parus_major | ENSPMJP00000010823 | 89.3375 | 80.6418 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 68.0166 | neolamprologus_brichardi | ENSNBRP00000023131 | 79.9176 | 67.4562 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 88.5774 | 78.0893 | naja_naja | ENSNNAP00000019854 | 88.8542 | 78.3333 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 89.8235 | 80.5815 | podarcis_muralis | ENSPMRP00000029240 | 89.8235 | 80.5815 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 72.0665 | geospiza_fortis | ENSGFOP00000020991 | 84.0737 | 75.1896 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 85.6698 | 77.0509 | taeniopygia_guttata | ENSTGUP00000003517 | 89.2857 | 80.303 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.27 | 67.2897 | kryptolebias_marmoratus | ENSKMAP00000021616 | 78.0808 | 65.4545 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 88.5774 | 77.2586 | salvator_merianae | ENSSMRP00000002187 | 88.5774 | 77.2586 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 67.7051 | oryzias_javanicus | ENSOJAP00000024554 | 78.4274 | 65.7258 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 68.3281 | amphilophus_citrinellus | ENSACIP00000016191 | 79.9794 | 67.9051 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 68.2243 | dicentrarchus_labrax | ENSDLAP00005059464 | 74.5925 | 62.9914 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.4123 | 68.7435 | amphiprion_percula | ENSAPEP00000012889 | 80.5755 | 68.037 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 67.8089 | oryzias_sinensis | ENSOSIP00000037518 | 78.3838 | 65.9596 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 83.6968 | 76.947 | pelodiscus_sinensis | ENSPSIP00000010930 | 91.5909 | 84.2045 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.2773 | 83.3853 | gopherus_evgoodei | ENSGEVP00005027213 | 92.235 | 84.2602 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 92.8349 | 85.1506 | chelonoidis_abingdonii | ENSCABP00000003068 | 89.9396 | 82.495 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 68.432 | seriola_dumerili | ENSSDUP00000032678 | 79.8561 | 67.7287 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.6469 | 66.7705 | cottoperca_gobio | ENSCGOP00000002564 | 79.9791 | 67.049 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 86.3967 | 78.8162 | struthio_camelus_australis | ENSSCUP00000021686 | 91.4286 | 83.4066 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.1734 | 82.5545 | anser_brachyrhynchus | ENSABRP00000005297 | 90.8903 | 82.2981 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.3738 | 67.8089 | gasterosteus_aculeatus | ENSGACP00000009765 | 80.2905 | 67.7386 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.8546 | 66.459 | cynoglossus_semilaevis | ENSCSEP00000004782 | 79.0339 | 65.7759 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 67.3936 | poecilia_formosa | ENSPFOP00000014698 | 78.5208 | 65.7548 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 68.2243 | myripristis_murdjan | ENSMMDP00005034197 | 79.6506 | 67.5231 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.1661 | 68.5358 | sander_lucioperca | ENSSLUP00000044238 | 79.6698 | 68.1115 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 90.758 | 82.0353 | strigops_habroptila | ENSSHBP00005020981 | 90.5699 | 81.8653 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.3084 | 68.7435 | amphiprion_ocellaris | ENSAOCP00000004094 | 80.6385 | 68.1771 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 93.2503 | 85.2544 | terrapene_carolina_triunguis | ENSTMTP00000028852 | 90.6155 | 82.8456 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.0353 | 68.5358 | hucho_hucho | ENSHHUP00000068117 | 81.4433 | 68.0412 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.7238 | 68.0166 | betta_splendens | ENSBSLP00000030812 | 79.4949 | 66.1616 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.6199 | 68.2243 | pygocentrus_nattereri | ENSPNAP00000020349 | 80.9475 | 67.6622 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.2046 | 68.1205 | anabas_testudineus | ENSATEP00000030631 | 80.2875 | 67.3511 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.893 | 68.432 | seriola_lalandi_dorsalis | ENSSLDP00000002162 | 80.0617 | 67.7287 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.4123 | 68.2243 | labrus_bergylta | ENSLBEP00000026847 | 80.6584 | 67.5926 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.5815 | 68.1205 | pundamilia_nyererei | ENSPNYP00000011915 | 79.9176 | 67.5592 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.893 | 68.0166 | mastacembelus_armatus | ENSMAMP00000034369 | 80.0617 | 67.3176 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 68.5358 | stegastes_partitus | ENSSPAP00000001201 | 80.0412 | 67.9012 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 82.1391 | 68.5358 | oncorhynchus_tshawytscha | ENSOTSP00005030966 | 81.5464 | 68.0412 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.9969 | 68.3281 | acanthochromis_polyacanthus | ENSAPOP00000013787 | 80 | 67.4872 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.9969 | 68.3281 | acanthochromis_polyacanthus | ENSAPOP00000032518 | 80 | 67.4872 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.9969 | 68.3281 | acanthochromis_polyacanthus | ENSAPOP00000012741 | 80 | 67.4872 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.0696 | 82.5545 | aquila_chrysaetos_chrysaetos | ENSACCP00020002267 | 90.8808 | 82.3834 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.0239 | 65.6282 | nothobranchius_furzeri | ENSNFUP00015030123 | 76.8687 | 63.8384 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 67.1859 | cyprinodon_variegatus | ENSCVAP00000008835 | 78.2828 | 65.3535 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 67.7051 | denticeps_clupeoides | ENSDCDP00000061527 | 79.5292 | 66.7349 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.893 | 68.7435 | larimichthys_crocea | ENSLCRP00005024511 | 78.0561 | 66.3327 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.8546 | 67.1859 | takifugu_rubripes | ENSTRUP00000040661 | 79.1152 | 66.5638 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 83.0737 | 74.7664 | ficedula_albicollis | ENSFALP00000011098 | 89.7868 | 80.8081 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 77.1547 | 63.9668 | hippocampus_comes | ENSHCOP00000020933 | 78.4583 | 65.0475 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 66.2513 | cyprinus_carpio_carpio | ENSCCRP00000081077 | 79.1455 | 64.9034 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.4777 | 65.6282 | cyprinus_carpio_carpio | ENSCCRP00000081007 | 79.8146 | 65.0875 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 91.0696 | 82.1391 | coturnix_japonica | ENSCJPP00005009101 | 90.8808 | 81.9689 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.3738 | 67.3936 | poecilia_latipinna | ENSPLAP00000019786 | 78.1818 | 65.5556 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.0623 | 66.3551 | sinocyclocheilus_grahami | ENSSGRP00000087635 | 78.8344 | 65.3374 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.3738 | 66.1475 | sinocyclocheilus_grahami | ENSSGRP00000070096 | 79.1411 | 65.1329 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 68.2243 | maylandia_zebra | ENSMZEP00005014552 | 80.2686 | 67.8719 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 16.8224 | 14.2264 | tetraodon_nigroviridis | ENSTNIP00000011286 | 65.0602 | 55.0201 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 81.3084 | 68.2243 | paramormyrops_kingsleyae | ENSPKIP00000032811 | 79.1709 | 66.4307 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 79.4393 | 66.459 | scleropages_formosus | ENSSFOP00015075593 | 76.2712 | 63.8086 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.1661 | 68.2243 | leptobrachium_leishanense | ENSLLEP00000008457 | 77.666 | 66.0966 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.6854 | 68.0166 | scophthalmus_maximus | ENSSMAP00000037810 | 79.8561 | 67.3176 |
ENSG00000136381 | homo_sapiens | ENSP00000258886 | 80.7892 | 67.7051 | oryzias_melastigma | ENSOMEP00000004149 | 78.9047 | 66.1258 |
Gene Ontology
Go ID | Go term | No. evidence | Entries | Species | Category |
---|---|---|---|---|---|
GO:0003723 | enables RNA binding | 2 | IDA,TAS | Homo_sapiens(9606) | Function |
GO:0003994 | enables aconitate hydratase activity | 1 | IBA | Homo_sapiens(9606) | Function |
GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
GO:0005737 | located_in cytoplasm | 1 | NAS | Homo_sapiens(9606) | Component |
GO:0005739 | is_active_in mitochondrion | 1 | IBA | Homo_sapiens(9606) | Component |
GO:0005829 | is_active_in cytosol | 2 | IBA,TAS | Homo_sapiens(9606) | Component |
GO:0006099 | involved_in tricarboxylic acid cycle | 1 | IBA | Homo_sapiens(9606) | Process |
GO:0006101 | involved_in citrate metabolic process | 1 | IBA | Homo_sapiens(9606) | Process |
GO:0006417 | involved_in regulation of translation | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0006782 | involved_in protoporphyrinogen IX biosynthetic process | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0006879 | involved_in intracellular iron ion homeostasis | 1 | IMP | Homo_sapiens(9606) | Process |
GO:0009791 | involved_in post-embryonic development | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0030316 | involved_in osteoclast differentiation | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0030350 | enables iron-responsive element binding | 3 | IBA,IMP,TAS | Homo_sapiens(9606) | Function |
GO:0034101 | involved_in erythrocyte homeostasis | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0046872 | enables metal ion binding | 1 | IEA | Homo_sapiens(9606) | Function |
GO:0048255 | involved_in mRNA stabilization | 1 | TAS | Homo_sapiens(9606) | Process |
GO:0050892 | involved_in intestinal absorption | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0051539 | enables 4 iron, 4 sulfur cluster binding | 1 | IBA | Homo_sapiens(9606) | Function |
GO:0051649 | involved_in establishment of localization in cell | 1 | IEA | Homo_sapiens(9606) | Process |
GO:0060586 | involved_in multicellular organismal-level iron ion homeostasis | 1 | IEA | Homo_sapiens(9606) | Process |