Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq DataSet_01_111 DataSet_01_270 DataSet_01_362 DataSet_02_18

Description

Ensembl ID ENSG00000136231 Gene ID 10643 Accession 28868
Symbol IGF2BP3 Alias KOC;CT98;IMP3;KOC1;IMP-3;VICKZ3 Full Name insulin like growth factor 2 mRNA binding protein 3
Status Confidence Length 160283 bases Strand Minus strand
Position 7 : 23310209 - 23470491 RNA binding domain KH_1 , RRM_1
Summary The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000258729 RRM_1 PF00076 2.3e-17 1
ENSP00000258729 RRM_1 PF00076 2.3e-17 2
ENSP00000258729 KH_1 PF00013 2.3e-56 3
ENSP00000258729 KH_1 PF00013 2.3e-56 4
ENSP00000258729 KH_1 PF00013 2.3e-56 5
ENSP00000258729 KH_1 PF00013 2.3e-56 6
ENSP00000395936 RRM_1 PF00076 1.6e-07 1
ENSP00000480267 KH_1 PF00013 1.2e-27 1
ENSP00000480267 KH_1 PF00013 1.2e-27 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37305324 IGF2BP3-induced activation of EIF5B contributes to progression of hepatocellular carcinoma cells. Xiaoyin Li 2022-01-01 Oncology research
32083017 Overexpression of IGF2BP3 as a Potential Oncogene in Ovarian Clear Cell Carcinoma. Huidi Liu 2019-01-01 Frontiers in oncology
35676262 IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression. Cuicui Wang 2022-06-08 Cell death discovery
33805930 IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia. Artturi Mäkinen 2021-03-25 Cancers
34986849 Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p. Yu-Zhong Yu 2022-01-05 Molecular cancer
30760837 DNA demethylation is associated with malignant progression of lower-grade gliomas. Masashi Nomura 2019-02-13 Scientific reports
31118463 Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3. Tim Schneider 2019-05-22 Nature communications
22840368 Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer. Paul Lochhead 2012-12-01 European journal of cancer (Oxford, England : 1990)
37207381 Advances in lung adenocarcinoma: A novel perspective on prognoses and immune responses of CENPO as an oncogenic superenhancer. Tongdong Shi 2023-08-01 Translational oncology
33279839 IGF2BP3 Expression Correlates With Poor Prognosis in Esophageal Squamous Cell Carcinoma. Akiyuki Wakita 2021-03-01 The Journal of surgical research
34008756 Prognostic implications of immune-related eight-gene signature in pediatric brain tumors. Yi Wang 2021-01-01 Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
36831493 RNA-Binding Proteins in Bladder Cancer. Yuanhui Gao 2023-02-10 Cancers
36761737 Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer. Pin Chen 2023-01-01 Frontiers in immunology
36030651 IGF2BP3-NRF2 axis regulates ferroptosis in hepatocellular carcinoma. Zhihua Lu 2022-10-30 Biochemical and biophysical research communications
29186811 Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts. G Maximilian Burger 2017-11-24 International journal of molecular sciences
37407973 CircGNB1 facilitates the malignant phenotype of GSCs by regulating miR-515-5p/miR-582-3p-XPR1 axis. Jinpeng Hu 2023-07-05 Cancer cell international
25216519 IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer. Keisuke Taniuchi 2014-08-30 Oncotarget
36338681 Polymorphic variants of IGF2BP3 and SENCR have an impact on predisposition and/or progression of Ewing sarcoma. Marcella Martinelli 2022-01-01 Frontiers in oncology
31451669 Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling. Zhaoning Wang 2019-09-10 Proceedings of the National Academy of Sciences of the United States of America
37353558 Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells. Caterina Mancarella 2023-06-23 Cancer gene therapy
27941992 High Expression of KIF20A Is Associated with Poor Overall Survival and Tumor Progression in Early-Stage Cervical Squamous Cell Carcinoma. Weijing Zhang 2016-01-01 PloS one

Transcripts

Name Transcript ID bp Protein Translation ID
IGF2BP3-201 ENST00000258729 4274 579aa ENSP00000258729
IGF2BP3-202 ENST00000421467 2988 81aa ENSP00000395936
IGF2BP3-217 ENST00000498363 529 No protein -
IGF2BP3-205 ENST00000467592 600 No protein -
IGF2BP3-216 ENST00000497563 657 No protein -
IGF2BP3-212 ENST00000480547 596 No protein -
IGF2BP3-215 ENST00000495009 452 No protein -
IGF2BP3-207 ENST00000468263 706 No protein -
IGF2BP3-214 ENST00000492771 564 No protein -
IGF2BP3-211 ENST00000479504 559 No protein -
IGF2BP3-204 ENST00000466809 588 No protein -
IGF2BP3-213 ENST00000491719 800 No protein -
IGF2BP3-203 ENST00000465058 534 No protein -
IGF2BP3-208 ENST00000469723 556 No protein -
IGF2BP3-209 ENST00000474105 663 No protein -
IGF2BP3-210 ENST00000476938 500 No protein -
IGF2BP3-206 ENST00000468005 2948 No protein -
IGF2BP3-218 ENST00000619562 2126 198aa ENSP00000480267

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
32731Body Mass Index4.5725990E-005-
32817Body Mass Index5.0777281E-005-
63249Body Height2E-1420881960
75104Hip2E-825673412
75105Body Mass Index2E-825673412
85544Body Height4E-2625282103
85944Body Height5E-1023563607
86008Personality5E-623903073
87462Hip1E-825673412
87463Body Mass Index1E-825673412
88388Body Height8E-825281659
94137Immunoglobulins2E-623382691

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136231homo_sapiensENSP0000029034183.535573.3102homo_sapiensENSP0000025872983.24773.057
ENSG00000136231homo_sapiensENSP0000041719637.220820.0993homo_sapiensENSP0000025872925.906713.9896
ENSG00000136231homo_sapiensENSP0000026325726.829313.8211homo_sapiensENSP0000025872922.797911.7444
ENSG00000136231homo_sapiensENSP0000050579639.892222.9111homo_sapiensENSP0000025872925.561314.6805
ENSG00000136231homo_sapiensENSP0000036543931.034517.6724homo_sapiensENSP0000025872924.870514.1623
ENSG00000136231homo_sapiensENSP0000044876241.988924.5856homo_sapiensENSP0000025872926.252215.3713
ENSG00000136231homo_sapiensENSP0000037163476.794763.606homo_sapiensENSP0000025872979.447365.8031
ENSG00000136231homo_sapiensENSP0000035980429.813716.9255homo_sapiensENSP0000025872933.160618.8256
ENSG00000136231homo_sapiensENSP0000031817732.692318.007homo_sapiensENSP0000025872932.297117.7893
ENSG00000136231homo_sapiensENSP0000030555641.853924.1573homo_sapiensENSP0000025872925.73414.8532
ENSG00000136231homo_sapiensENSP0000043887526.232713.8067homo_sapiensENSP0000025872922.970612.0898
ENSG00000136231homo_sapiensENSP0000047114627.57715.7965homo_sapiensENSP0000025872935.578620.38

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000136231homo_sapiensENSP0000025872999.481999.1364nomascus_leucogenysENSNLEP0000001798598.293597.9522
ENSG00000136231homo_sapiensENSP00000258729100100pan_paniscusENSPPAP00000021170100100
ENSG00000136231homo_sapiensENSP00000258729100100pongo_abeliiENSPPYP00000042932100100
ENSG00000136231homo_sapiensENSP00000258729100100pan_troglodytesENSPTRP00000032446100100
ENSG00000136231homo_sapiensENSP0000025872989.8189.81gorilla_gorillaENSGGOP00000020311100100
ENSG00000136231homo_sapiensENSP0000025872992.746186.3558ornithorhynchus_anatinusENSOANP0000003631589.649483.4725
ENSG00000136231homo_sapiensENSP0000025872983.765174.6114sarcophilus_harrisiiENSSHAP0000000826967.454860.0835
ENSG00000136231homo_sapiensENSP0000025872968.739261.4853notamacropus_eugeniiENSMEUP0000001141668.384961.1684
ENSG00000136231homo_sapiensENSP0000025872989.982789.1192choloepus_hoffmanniENSCHOP0000000207089.982789.1192
ENSG00000136231homo_sapiensENSP0000025872986.010484.6287dasypus_novemcinctusENSDNOP0000003026990.217488.7681
ENSG00000136231homo_sapiensENSP0000025872969.430168.9119erinaceus_europaeusENSEEUP0000000430869.430168.9119
ENSG00000136231homo_sapiensENSP0000025872983.24782.038echinops_telfairiENSETEP0000001262392.160690.8222
ENSG00000136231homo_sapiensENSP0000025872999.481999.3092callithrix_jacchusENSCJAP0000000268499.481999.3092
ENSG00000136231homo_sapiensENSP0000025872910099.8273cercocebus_atysENSCATP0000002504710099.8273
ENSG00000136231homo_sapiensENSP0000025872910099.8273macaca_fascicularisENSMFAP0000003275494.91894.7541
ENSG00000136231homo_sapiensENSP0000025872910099.8273macaca_mulattaENSMMUP0000003515410099.8273
ENSG00000136231homo_sapiensENSP0000025872910099.8273macaca_nemestrinaENSMNEP0000001014410099.8273
ENSG00000136231homo_sapiensENSP0000025872910099.8273papio_anubisENSPANP0000000778110099.8273
ENSG00000136231homo_sapiensENSP0000025872910099.8273mandrillus_leucophaeusENSMLEP0000000083510099.8273
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183tursiops_truncatusENSTTRP0000000846299.309298.6183
ENSG00000136231homo_sapiensENSP0000025872999.136498.6183vulpes_vulpesENSVVUP0000000126799.136498.6183
ENSG00000136231homo_sapiensENSP0000025872998.272996.5458mus_spretusMGP_SPRETEiJ_P007661998.272996.5458
ENSG00000136231homo_sapiensENSP0000025872998.963798.1002equus_asinusENSEASP0000505941698.963798.1002
ENSG00000136231homo_sapiensENSP0000025872998.79197.582capra_hircusENSCHIP0000003152098.620797.4138
ENSG00000136231homo_sapiensENSP0000025872983.074382.7288loxodonta_africanaENSLAFP0000002450798.565698.1557
ENSG00000136231homo_sapiensENSP0000025872999.309298.791panthera_leoENSPLOP0000000849099.309298.791
ENSG00000136231homo_sapiensENSP0000025872999.136498.2729ailuropoda_melanoleucaENSAMEP0000000367699.136498.2729
ENSG00000136231homo_sapiensENSP0000025872999.136497.7548bos_indicus_hybridENSBIXP0000501707498.965597.5862
ENSG00000136231homo_sapiensENSP0000025872988.428387.3921oryctolagus_cuniculusENSOCUP0000000775497.153796.0152
ENSG00000136231homo_sapiensENSP0000025872934.196934.1969equus_caballusENSECAP00000014668100100
ENSG00000136231homo_sapiensENSP0000025872916.925714.1623equus_caballusENSECAP0000005801483.050869.4915
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183canis_lupus_familiarisENSCAFP0084501286899.309298.6183
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183panthera_pardusENSPPRP0000002693499.309298.6183
ENSG00000136231homo_sapiensENSP0000025872999.309298.9637marmota_marmota_marmotaENSMMMP0000000591299.309298.9637
ENSG00000136231homo_sapiensENSP0000025872999.136498.4456balaenoptera_musculusENSBMSP0001001007299.136498.4456
ENSG00000136231homo_sapiensENSP0000025872988.946588.2556cavia_porcellusENSCPOP0000001358499.229398.4586
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183felis_catusENSFCAP0000001665799.309298.6183
ENSG00000136231homo_sapiensENSP0000025872981.347280.829ursus_americanusENSUAMP0000002817196.714696.0986
ENSG00000136231homo_sapiensENSP0000025872987.737579.4473monodelphis_domesticaENSMODP0000000121983.415475.5337
ENSG00000136231homo_sapiensENSP0000025872997.236695.8549bison_bison_bisonENSBBBP0000002227098.945597.5395
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183monodon_monocerosENSMMNP0001501854299.309298.6183
ENSG00000136231homo_sapiensENSP0000025872988.773886.7012sus_scrofaENSSSCP0000004423887.713385.6655
ENSG00000136231homo_sapiensENSP0000025872999.654699.4819microcebus_murinusENSMICP0000001248899.654699.4819
ENSG00000136231homo_sapiensENSP0000025872915.025913.2988octodon_degusENSODEP0000001757661.702154.6099
ENSG00000136231homo_sapiensENSP0000025872912.780712.4352octodon_degusENSODEP0000001224393.670991.1392
ENSG00000136231homo_sapiensENSP0000025872998.445697.582jaculus_jaculusENSJJAP0000000652198.445697.582
ENSG00000136231homo_sapiensENSP0000025872998.79197.582ovis_aries_rambouilletENSOARP0002000884898.79197.582
ENSG00000136231homo_sapiensENSP0000025872994.473292.4007ursus_maritimusENSUMAP0000000111495.629493.5315
ENSG00000136231homo_sapiensENSP0000025872971.502670.2936ochotona_princepsENSOPRP0000000959582.881.4
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183delphinapterus_leucasENSDLEP0000003052399.309298.6183
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183physeter_catodonENSPCTP0000500445499.309298.6183
ENSG00000136231homo_sapiensENSP0000025872998.272996.7185mus_caroliMGP_CAROLIEiJ_P007375198.272996.7185
ENSG00000136231homo_sapiensENSP0000025872998.272996.5458mus_musculusENSMUSP0000003183898.272996.5458
ENSG00000136231homo_sapiensENSP0000025872998.963798.2729dipodomys_ordiiENSDORP0000001333998.963798.2729
ENSG00000136231homo_sapiensENSP0000025872998.963798.1002mustela_putorius_furoENSMPUP0000001342498.963798.1002
ENSG00000136231homo_sapiensENSP0000025872999.481998.791aotus_nancymaaeENSANAP0000000806299.481998.791
ENSG00000136231homo_sapiensENSP0000025872999.481999.3092saimiri_boliviensis_boliviensisENSSBOP0000000546099.481999.3092
ENSG00000136231homo_sapiensENSP0000025872989.291989.1192vicugna_pacosENSVPAP0000000056899.423199.2308
ENSG00000136231homo_sapiensENSP0000025872983.419783.4197chlorocebus_sabaeusENSCSAP0000001011899.793499.7934
ENSG00000136231homo_sapiensENSP0000025872971.329970.639tupaia_belangeriENSTBEP0000000101679.270678.5029
ENSG00000136231homo_sapiensENSP0000025872997.236695.6822mesocricetus_auratusENSMAUP0000000229497.236695.6822
ENSG00000136231homo_sapiensENSP0000025872999.136498.4456phocoena_sinusENSPSNP0000001336599.136498.4456
ENSG00000136231homo_sapiensENSP0000025872999.309298.9637camelus_dromedariusENSCDRP0000500020099.309298.9637
ENSG00000136231homo_sapiensENSP0000025872999.654699.1364carlito_syrichtaENSTSYP0000001161899.654699.1364
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183panthera_tigris_altaicaENSPTIP0000000321599.309298.6183
ENSG00000136231homo_sapiensENSP0000025872998.272996.8912rattus_norvegicusENSRNOP0000007162698.272996.8912
ENSG00000136231homo_sapiensENSP0000025872987.046685.8377prolemur_simusENSPSMP0000000604594.736893.4211
ENSG00000136231homo_sapiensENSP0000025872996.891295.3368microtus_ochrogasterENSMOCP0000000221696.891295.3368
ENSG00000136231homo_sapiensENSP0000025872980.82980.1382sorex_araneusENSSARP0000000597089.31388.5496
ENSG00000136231homo_sapiensENSP0000025872997.58295.8549peromyscus_maniculatus_bairdiiENSPEMP0000002772497.58295.8549
ENSG00000136231homo_sapiensENSP0000025872999.136497.7548bos_mutusENSBMUP0000002930199.136497.7548
ENSG00000136231homo_sapiensENSP0000025872998.272996.5458mus_spicilegusENSMSIP0000002418898.272996.5458
ENSG00000136231homo_sapiensENSP0000025872997.58295.6822cricetulus_griseus_chok1gshdENSCGRP0000100978997.58295.6822
ENSG00000136231homo_sapiensENSP0000025872979.274678.7565pteropus_vampyrusENSPVAP0000001064888.269287.6923
ENSG00000136231homo_sapiensENSP0000025872982.901681.8653myotis_lucifugusENSMLUP0000000771194.488293.3071
ENSG00000136231homo_sapiensENSP0000025872982.728873.9206vombatus_ursinusENSVURP0001002625783.741374.8252
ENSG00000136231homo_sapiensENSP0000025872982.728873.9206vombatus_ursinusENSVURP0001000211883.741374.8252
ENSG00000136231homo_sapiensENSP0000025872999.136498.791rhinolophus_ferrumequinumENSRFEP0001001395599.136498.791
ENSG00000136231homo_sapiensENSP0000025872995.164193.6097neovison_visonENSNVIP0000001666391.986690.4841
ENSG00000136231homo_sapiensENSP0000025872999.136497.7548bos_taurusENSBTAP0000002585498.965597.5862
ENSG00000136231homo_sapiensENSP0000025872999.309298.2729heterocephalus_glaber_femaleENSHGLP0000001826799.309298.2729
ENSG00000136231homo_sapiensENSP0000025872910099.8273rhinopithecus_bietiENSRBIP0000001803910099.8273
ENSG00000136231homo_sapiensENSP0000025872999.309298.6183canis_lupus_dingoENSCAFP0002000321299.309298.6183
ENSG00000136231homo_sapiensENSP0000025872913.644213.4715sciurus_vulgarisENSSVLP0000502438810098.7342
ENSG00000136231homo_sapiensENSP0000025872934.024233.8515sciurus_vulgarisENSSVLP0000502427110099.4924
ENSG00000136231homo_sapiensENSP0000025872987.737578.5838phascolarctos_cinereusENSPCIP0000000972780.126271.7666
ENSG00000136231homo_sapiensENSP0000025872963.903363.0397procavia_capensisENSPCAP0000000942571.844770.8738
ENSG00000136231homo_sapiensENSP0000025872998.618397.9275nannospalax_galiliENSNGAP0000002571598.618397.9275
ENSG00000136231homo_sapiensENSP0000025872999.136497.7548bos_grunniensENSBGRP0000000050095.190793.864
ENSG00000136231homo_sapiensENSP0000025872999.136498.791chinchilla_lanigeraENSCLAP0000001425399.136498.791
ENSG00000136231homo_sapiensENSP0000025872998.618397.0639cervus_hanglu_yarkandensisENSCHYP0000002035293.760392.2824
ENSG00000136231homo_sapiensENSP0000025872997.58296.8912catagonus_wagneriENSCWAP0000000150197.58296.8912
ENSG00000136231homo_sapiensENSP0000025872999.309298.9637ictidomys_tridecemlineatusENSSTOP0000000764299.309298.9637
ENSG00000136231homo_sapiensENSP0000025872999.654699.6546otolemur_garnettiiENSOGAP0000001537199.654699.6546
ENSG00000136231homo_sapiensENSP0000025872999.481999.3092cebus_imitatorENSCCAP0000001971099.481999.3092
ENSG00000136231homo_sapiensENSP0000025872999.309298.9637urocitellus_parryiiENSUPAP0001001916599.309298.9637
ENSG00000136231homo_sapiensENSP0000025872998.963797.582moschus_moschiferusENSMMSP0000003313598.963797.582
ENSG00000136231homo_sapiensENSP0000025872910099.8273rhinopithecus_roxellanaENSRROP0000002302710099.8273
ENSG00000136231homo_sapiensENSP0000025872998.272996.8912mus_pahariMGP_PahariEiJ_P004984298.272996.8912
ENSG00000136231homo_sapiensENSP0000025872913.644213.4715propithecus_coquereliENSPCOP0000001088010098.7342
ENSG00000136231homo_sapiensENSP0000025872919.34378.80829caenorhabditis_elegansY119D3B.17.225.925911.8056
ENSG00000136231homo_sapiensENSP0000025872915.02597.94473caenorhabditis_elegansY59A8B.10d.120.863311.0312
ENSG00000136231homo_sapiensENSP0000025872925.906714.1623caenorhabditis_elegansC36E6.1b.123.400912.7925
ENSG00000136231homo_sapiensENSP0000025872925.561312.9534caenorhabditis_elegansM01A10.1.125.25612.7986
ENSG00000136231homo_sapiensENSP0000025872943.350625.5613caenorhabditis_elegansM88.5c.129.391117.3302
ENSG00000136231homo_sapiensENSP0000025872926.079413.9896drosophila_melanogasterFBpp029352126.352514.1361
ENSG00000136231homo_sapiensENSP0000025872922.452510.7081drosophila_melanogasterFBpp030641916.66677.94872
ENSG00000136231homo_sapiensENSP0000025872951.295335.4059drosophila_melanogasterFBpp029368046.551732.1317
ENSG00000136231homo_sapiensENSP0000025872920.725411.0535ciona_intestinalisENSCINP0000000198433.613417.9272
ENSG00000136231homo_sapiensENSP0000025872917.78938.46287ciona_intestinalisENSCINP0000002595036.267617.2535
ENSG00000136231homo_sapiensENSP0000025872962.694345.4231ciona_intestinalisENSCINP0000000872661.421344.5008
ENSG00000136231homo_sapiensENSP0000025872962.348954.4041petromyzon_marinusENSPMAP0000000354978.478368.4783
ENSG00000136231homo_sapiensENSP0000025872925.73419.171eptatretus_burgeriENSEBUP0000000919571.634653.3654
ENSG00000136231homo_sapiensENSP0000025872980.310972.1934callorhinchus_miliiENSCMIP0000004039283.633175.1799
ENSG00000136231homo_sapiensENSP0000025872969.430163.3851latimeria_chalumnaeENSLACP0000001473383.575976.2994
ENSG00000136231homo_sapiensENSP0000025872988.773880.4836lepisosteus_oculatusENSLOCP0000001426583.306375.5267
ENSG00000136231homo_sapiensENSP0000025872985.146874.7841clupea_harengusENSCHAP0000002901582.303872.2871
ENSG00000136231homo_sapiensENSP0000025872986.010477.0294danio_rerioENSDARP0000001087885.56776.6323
ENSG00000136231homo_sapiensENSP0000025872986.183176.8567carassius_auratusENSCARP0000006687383.166774.1667
ENSG00000136231homo_sapiensENSP0000025872983.074374.266carassius_auratusENSCARP0000004714176.9668.8
ENSG00000136231homo_sapiensENSP0000025872986.010477.0294astyanax_mexicanusENSAMXP0000004305281.773473.2348
ENSG00000136231homo_sapiensENSP0000025872984.628775.6477ictalurus_punctatusENSIPUP0000000892584.482875.5172
ENSG00000136231homo_sapiensENSP0000025872985.664976.3385esox_luciusENSELUP0000007351075.494767.2755
ENSG00000136231homo_sapiensENSP0000025872984.801474.7841electrophorus_electricusENSEEEP0000001725381.15771.5703
ENSG00000136231homo_sapiensENSP0000025872985.492276.1658oncorhynchus_kisutchENSOKIP0000510084979.326970.6731
ENSG00000136231homo_sapiensENSP0000025872984.974175.3022oncorhynchus_kisutchENSOKIP0000501388476.755168.0187
ENSG00000136231homo_sapiensENSP0000025872985.492276.1658oncorhynchus_mykissENSOMYP0000002803079.326970.6731
ENSG00000136231homo_sapiensENSP0000025872984.974175.3022oncorhynchus_mykissENSOMYP0000001534178.219469.3164
ENSG00000136231homo_sapiensENSP0000025872985.492276.1658salmo_salarENSSSAP0000003337578.947470.3349
ENSG00000136231homo_sapiensENSP0000025872984.974175.3022salmo_salarENSSSAP0000003336778.972769.9839
ENSG00000136231homo_sapiensENSP0000025872984.974175.475salmo_truttaENSSTUP0000010497278.219469.4754
ENSG00000136231homo_sapiensENSP0000025872985.319576.1658salmo_truttaENSSTUP0000004701179.0470.56
ENSG00000136231homo_sapiensENSP0000025872980.82970.9845gadus_morhuaENSGMOP0000003743975.483966.2903
ENSG00000136231homo_sapiensENSP0000025872984.45674.7841fundulus_heteroclitusENSFHEP0000001433183.304973.7649
ENSG00000136231homo_sapiensENSP0000025872984.801474.9568poecilia_reticulataENSPREP0000000245580.756671.3816
ENSG00000136231homo_sapiensENSP0000025872984.801475.3022xiphophorus_maculatusENSXMAP0000002856980.756671.7105
ENSG00000136231homo_sapiensENSP0000025872984.628775.6477oryzias_latipesENSORLP0000000593180.459871.9212
ENSG00000136231homo_sapiensENSP0000025872983.592474.4387cyclopterus_lumpusENSCLMP0000504106780.398771.5947
ENSG00000136231homo_sapiensENSP0000025872981.001771.5026oreochromis_niloticusENSONIP0000004547476.50967.5367
ENSG00000136231homo_sapiensENSP0000025872984.801475.8204haplochromis_burtoniENSHBUP0000001623283.361674.5331
ENSG00000136231homo_sapiensENSP0000025872984.801475.8204astatotilapia_callipteraENSACLP0000000006483.503474.6599
ENSG00000136231homo_sapiensENSP0000025872983.765173.9206sparus_aurataENSSAUP0001005360180.165370.7438
ENSG00000136231homo_sapiensENSP0000025872979.965571.5026lates_calcariferENSLCAP0001003645479.280870.8904
ENSG00000136231homo_sapiensENSP0000025872984.110577.0294xenopus_tropicalisENSXETP0000001610687.432780.0718
ENSG00000136231homo_sapiensENSP0000025872992.22885.3195chrysemys_picta_belliiENSCPBP0000003200191.438484.589
ENSG00000136231homo_sapiensENSP0000025872988.255681.3472sphenodon_punctatusENSSPUP0000000797489.806782.7768
ENSG00000136231homo_sapiensENSP0000025872989.291982.3834crocodylus_porosusENSCPRP0000502291982.456176.0766
ENSG00000136231homo_sapiensENSP0000025872948.53244.3869laticauda_laticaudataENSLLTP0000000835688.643581.0726
ENSG00000136231homo_sapiensENSP0000025872912.607911.399notechis_scutatusENSNSUP0000002087785.882477.6471
ENSG00000136231homo_sapiensENSP0000025872945.595942.6598notechis_scutatusENSNSUP0000002087892.631686.6667
ENSG00000136231homo_sapiensENSP0000025872987.392180.3109pseudonaja_textilisENSPTXP0000002053289.875782.5933
ENSG00000136231homo_sapiensENSP0000025872992.22886.0104anas_platyrhynchos_platyrhynchosENSAPLP0000001311691.438485.274
ENSG00000136231homo_sapiensENSP0000025872989.982783.7651gallus_gallusENSGALP0001000185683.226877.476
ENSG00000136231homo_sapiensENSP0000025872982.210775.6477meleagris_gallopavoENSMGAP0000002606388.148181.1111
ENSG00000136231homo_sapiensENSP0000025872982.383475.8204serinus_canariaENSSCAP0000002068783.10176.4808
ENSG00000136231homo_sapiensENSP0000025872992.22886.0104parus_majorENSPMJP0000000088191.438485.274
ENSG00000136231homo_sapiensENSP0000025872992.055384.8014anolis_carolinensisENSACAP0000001334191.267184.0753
ENSG00000136231homo_sapiensENSP0000025872976.165867.7029neolamprologus_brichardiENSNBRP0000000765483.522774.2424
ENSG00000136231homo_sapiensENSP0000025872987.564880.3109naja_najaENSNNAP0000002082985.210178.1513
ENSG00000136231homo_sapiensENSP0000025872986.701279.4473podarcis_muralisENSPMRP0000002696272.230266.187
ENSG00000136231homo_sapiensENSP0000025872981.692675.3022geospiza_fortisENSGFOP0000001520284.76778.1362
ENSG00000136231homo_sapiensENSP0000025872992.22886.0104taeniopygia_guttataENSTGUP0000000287291.438485.274
ENSG00000136231homo_sapiensENSP0000025872987.219379.4473erpetoichthys_calabaricusENSECRP0000001702888.441380.5604
ENSG00000136231homo_sapiensENSP0000025872983.937874.9568kryptolebias_marmoratusENSKMAP0000002676480.463671.8543
ENSG00000136231homo_sapiensENSP0000025872955.613144.905salvator_merianaeENSSMRP0000002684780.701865.1629
ENSG00000136231homo_sapiensENSP0000025872991.709884.1105salvator_merianaeENSSMRP0000000414186.341579.187
ENSG00000136231homo_sapiensENSP0000025872977.029467.3575oryzias_javanicusENSOJAP0000001287278.383168.5413
ENSG00000136231homo_sapiensENSP0000025872983.592474.7841amphilophus_citrinellusENSACIP0000000172883.161574.3986
ENSG00000136231homo_sapiensENSP0000025872984.45675.8204dicentrarchus_labraxENSDLAP0000501684480.693172.4422
ENSG00000136231homo_sapiensENSP0000025872984.110575.475amphiprion_perculaENSAPEP0000002620683.67775.0859
ENSG00000136231homo_sapiensENSP0000025872984.628775.475oryzias_sinensisENSOSIP0000002099080.592171.875
ENSG00000136231homo_sapiensENSP0000025872991.364483.7651pelodiscus_sinensisENSPSIP0000001599690.427482.906
ENSG00000136231homo_sapiensENSP0000025872988.60181.6926gopherus_evgoodeiENSGEVP0000502631191.77184.6154
ENSG00000136231homo_sapiensENSP0000025872992.22885.1468chelonoidis_abingdoniiENSCABP0000000067991.282184.2735
ENSG00000136231homo_sapiensENSP0000025872984.110575.475seriola_dumeriliENSSDUP0000000758383.67775.0859
ENSG00000136231homo_sapiensENSP0000025872983.074374.0933cottoperca_gobioENSCGOP0000000997479.767871.1443
ENSG00000136231homo_sapiensENSP0000025872979.792772.5389struthio_camelus_australisENSSCUP0000000967582.575
ENSG00000136231homo_sapiensENSP0000025872981.174473.5751anser_brachyrhynchusENSABRP0000001175577.943670.6468
ENSG00000136231homo_sapiensENSP0000025872969.084661.4853gasterosteus_aculeatusENSGACP0000000919675.614467.2968
ENSG00000136231homo_sapiensENSP0000025872981.001770.8117cynoglossus_semilaevisENSCSEP0000001895978.691368.7919
ENSG00000136231homo_sapiensENSP0000025872984.974175.1295poecilia_formosaENSPFOP0000000618680.788271.4286
ENSG00000136231homo_sapiensENSP0000025872983.24774.0933myripristis_murdjanENSMMDP0000504787581.556772.5888
ENSG00000136231homo_sapiensENSP0000025872983.074373.9206sander_luciopercaENSSLUP0000000413580.300571.4524
ENSG00000136231homo_sapiensENSP0000025872992.22886.0104strigops_habroptilaENSSHBP0000500692291.438485.274
ENSG00000136231homo_sapiensENSP0000025872911.744410.0173amphiprion_ocellarisENSAOCP0000002691783.950671.6049
ENSG00000136231homo_sapiensENSP0000025872964.248758.3765amphiprion_ocellarisENSAOCP0000001122583.221575.6152
ENSG00000136231homo_sapiensENSP0000025872992.22885.3195terrapene_carolina_triunguisENSTMTP0000000691691.438484.589
ENSG00000136231homo_sapiensENSP0000025872985.146875.6477hucho_huchoENSHHUP0000007086578.378469.6343
ENSG00000136231homo_sapiensENSP0000025872985.492276.1658hucho_huchoENSHHUP0000000701878.696370.1113
ENSG00000136231homo_sapiensENSP0000025872984.628774.9568betta_splendensENSBSLP0000003279380.724971.4992
ENSG00000136231homo_sapiensENSP0000025872985.492277.0294pygocentrus_nattereriENSPNAP0000000088284.905776.5009
ENSG00000136231homo_sapiensENSP0000025872984.45675.3022anabas_testudineusENSATEP0000000099980.826472.0661
ENSG00000136231homo_sapiensENSP0000025872917.27129.32642ciona_savignyiENSCSAVP0000000475547.61925.7143
ENSG00000136231homo_sapiensENSP000002587299.671854.66321ciona_savignyiENSCSAVP0000000721445.901622.1311
ENSG00000136231homo_sapiensENSP0000025872962.176244.7323ciona_savignyiENSCSAVP0000001881362.06944.6552
ENSG00000136231homo_sapiensENSP0000025872984.110575.475seriola_lalandi_dorsalisENSSLDP0000003344183.533474.9571
ENSG00000136231homo_sapiensENSP0000025872983.419773.7478labrus_bergyltaENSLBEP0000000698879.70370.462
ENSG00000136231homo_sapiensENSP0000025872976.165867.7029pundamilia_nyerereiENSPNYP0000002679583.522774.2424
ENSG00000136231homo_sapiensENSP0000025872984.974175.8204mastacembelus_armatusENSMAMP0000006587481.054472.3229
ENSG00000136231homo_sapiensENSP0000025872976.683966.494stegastes_partitusENSSPAP0000000537680.144469.4946
ENSG00000136231homo_sapiensENSP0000025872985.492276.1658oncorhynchus_tshawytschaENSOTSP0000502198279.326970.6731
ENSG00000136231homo_sapiensENSP0000025872984.974175.3022oncorhynchus_tshawytschaENSOTSP0000500809378.219469.3164
ENSG00000136231homo_sapiensENSP0000025872984.283275.6477acanthochromis_polyacanthusENSAPOP0000003063983.70575.1286
ENSG00000136231homo_sapiensENSP0000025872992.22886.0104aquila_chrysaetos_chrysaetosENSACCP0002001288491.438485.274
ENSG00000136231homo_sapiensENSP0000025872984.801475.8204nothobranchius_furzeriENSNFUP0001504053381.291472.6821
ENSG00000136231homo_sapiensENSP0000025872976.511267.3575cyprinodon_variegatusENSCVAP0000000724582.649372.7612
ENSG00000136231homo_sapiensENSP0000025872981.174470.9845denticeps_clupeoidesENSDCDP0000002830481.174470.9845
ENSG00000136231homo_sapiensENSP0000025872982.556173.5751larimichthys_croceaENSLCRP0000503853578.489369.9507
ENSG00000136231homo_sapiensENSP0000025872983.074373.5751takifugu_rubripesENSTRUP0000005952979.504170.4132
ENSG00000136231homo_sapiensENSP0000025872990.328283.7651ficedula_albicollisENSFALP0000003209788.945682.483
ENSG00000136231homo_sapiensENSP0000025872977.547568.7392hippocampus_comesENSHCOP0000002033682.536873.1618
ENSG00000136231homo_sapiensENSP0000025872986.010477.0294cyprinus_carpio_carpioENSCCRP0000017580882.724374.0864
ENSG00000136231homo_sapiensENSP0000025872985.837777.3748cyprinus_carpio_carpioENSCCRP0000007616180.944672.9642
ENSG00000136231homo_sapiensENSP0000025872991.882685.3195coturnix_japonicaENSCJPP0000501502490.630384.1567
ENSG00000136231homo_sapiensENSP0000025872927.979325.2159poecilia_latipinnaENSPLAP0000002407378.640870.8738
ENSG00000136231homo_sapiensENSP0000025872984.974175.1295poecilia_latipinnaENSPLAP0000000575683.95974.2321
ENSG00000136231homo_sapiensENSP0000025872985.837777.3748sinocyclocheilus_grahamiENSSGRP0000010332781.878173.8056
ENSG00000136231homo_sapiensENSP0000025872984.283275.475sinocyclocheilus_grahamiENSSGRP0000009779982.154973.569
ENSG00000136231homo_sapiensENSP0000025872984.801475.8204maylandia_zebraENSMZEP0000501222083.361674.5331
ENSG00000136231homo_sapiensENSP0000025872982.728873.2297tetraodon_nigroviridisENSTNIP0000002090682.302472.8522
ENSG00000136231homo_sapiensENSP0000025872984.45675.3022paramormyrops_kingsleyaeENSPKIP0000003215582.881473.8983
ENSG00000136231homo_sapiensENSP0000025872986.701276.6839scleropages_formosusENSSFOP0001506996283.806374.1235
ENSG00000136231homo_sapiensENSP0000025872991.364483.7651leptobrachium_leishanenseENSLLEP0000000951387.006679.7697
ENSG00000136231homo_sapiensENSP0000025872982.210772.8843scophthalmus_maximusENSSMAP0000002345174.25965.8346
ENSG00000136231homo_sapiensENSP0000025872984.283275.1295oryzias_melastigmaENSOMEP0000001627883.418874.359

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000932located_in P-body1IDAHomo_sapiens(9606)Component
GO:0001817involved_in regulation of cytokine production1ICHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006412involved_in translation1TASHomo_sapiens(9606)Process
GO:0007399involved_in nervous system development1IBAHomo_sapiens(9606)Process
GO:0009653involved_in anatomical structure morphogenesis1TASHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0017148involved_in negative regulation of translation1ISSHomo_sapiens(9606)Process
GO:0045182enables translation regulator activity1ISSHomo_sapiens(9606)Function
GO:0048027enables mRNA 5-UTR binding1IDAHomo_sapiens(9606)Function
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0070934involved_in CRD-mediated mRNA stabilization1IDAHomo_sapiens(9606)Process
GO:1990247enables N6-methyladenosine-containing RNA binding1IDAHomo_sapiens(9606)Function

Expression