Ensembl ID ENSG00000136231 Gene ID 10643 Accession 28868
Gene Symbol IGF2BP3 Alias KOC;CT98;IMP3;KOC1;IMP-3;VICKZ3 Full Name insulin like growth factor 2 mRNA binding protein 3
Position 7 : 23310209 - 23470491 Length 160283 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

ENSG00000136231 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000136231 IGF2BP3 3.72 3.27e-37 KIRC
ENSG00000136231 IGF2BP3 2.04 6.82e-14 HNSC
ENSG00000136231 IGF2BP3 4.36 3.75e-14 BLCA
ENSG00000136231 IGF2BP3 2.26 1.68e-21 BRCA
ENSG00000136231 IGF2BP3 4.15 5.59e-26 COAD
ENSG00000136231 IGF2BP3 4.11 3.06e-19 KICH
ENSG00000136231 IGF2BP3 4.99 2.52e-120 LUSC
ENSG00000136231 IGF2BP3 6.14 1.09e-25 GBM
ENSG00000136231 IGF2BP3 3.62 1.24e-14 KIRP
ENSG00000136231 IGF2BP3 4.77 1.52e-38 LIHC
ENSG00000136231 IGF2BP3 3.16 1.69e-21 STAD
ENSG00000136231 IGF2BP3 4.29 2.18e-30 UCEC
ENSG00000136231 IGF2BP3 3.99 2.99e-48 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000136231 IGF2BP3 tumor 16838325
ENSG00000136231 IGF2BP3 tumors 18416826
ENSG00000136231 IGF2BP3 tumor 20178612
ENSG00000136231 IGF2BP3 soft tissue tumors 21414819
ENSG00000136231 IGF2BP3 cancer 21814862
ENSG00000136231 IGF2BP3 tumor 22280838
ENSG00000136231 IGF2BP3 tumor 22555177
ENSG00000136231 IGF2BP3 tumor 22763829
ENSG00000136231 IGF2BP3 colorectal cancer 22840368
ENSG00000136231 IGF2BP3 cancer 22879911
ENSG00000136231 IGF2BP3 esophageal cancers 22989274
ENSG00000136231 IGF2BP3 cancer 23069990
ENSG00000136231 IGF2BP3 cancer 23264902
ENSG00000136231 IGF2BP3 tumors 23584203
ENSG00000136231 IGF2BP3 tumor 23647076
ENSG00000136231 IGF2BP3 tumors 23677615
ENSG00000136231 IGF2BP3 cancers 24457969
ENSG00000136231 IGF2BP3 colorectal cancer 24612787
ENSG00000136231 IGF2BP3 tumor 24647926
ENSG00000136231 IGF2BP3 tumor 24708624
ENSG00000136231 IGF2BP3 cancer 25068994
ENSG00000136231 IGF2BP3 pancreatic cancer 25216519
ENSG00000136231 IGF2BP3 tumor 25427905
ENSG00000136231 IGF2BP3 pancreatic cancer 25499221
ENSG00000136231 IGF2BP3 tumor 25960008
ENSG00000136231 IGF2BP3 cancers 25982283
ENSG00000136231 IGF2BP3 tumor 26100984
ENSG00000136231 IGF2BP3 ovarian cancer 26158423
ENSG00000136231 IGF2BP3 colorectal cancers 26244168
ENSG00000136231 IGF2BP3 tumor 26327240
ENSG00000136231 IGF2BP3 GBM 26510428
ENSG00000136231 IGF2BP3 cancers 26522719
ENSG00000136231 IGF2BP3 tumors 26782292
ENSG00000136231 IGF2BP3 Cancer 26796627
ENSG00000136231 IGF2BP3 tumors 26917013
ENSG00000136231 IGF2BP3 tumors 26984550
ENSG00000136231 IGF2BP3 tumor 27072896
ENSG00000136231 IGF2BP3 tumor 27399126
ENSG00000136231 IGF2BP3 tumor 27510448
ENSG00000136231 IGF2BP3 tumors 27626165
ENSG00000136231 IGF2BP3 thyroid cancer 28193878
ENSG00000136231 IGF2BP3 lung cancer 28260111
ENSG00000136231 IGF2BP3 tumor 28381175
ENSG00000136231 IGF2BP3 tumor 28399871
ENSG00000136231 IGF2BP3 GBM 28465487
ENSG00000136231 IGF2BP3 breast cancer 28523716
ENSG00000136231 IGF2BP3 cancers 28814885
ENSG00000136231 IGF2BP3 gastric cancer 29088808
ENSG00000136231 IGF2BP3 cancer 29177029
ENSG00000136231 IGF2BP3 cancers 29212181
ENSG00000136231 IGF2BP3 tumor 29308320
ENSG00000136231 IGF2BP3 tumor 29660014
ENSG00000136231 IGF2BP3 tumor 29731738
ENSG00000136231 IGF2BP3 testicular cancers 29736175
ENSG00000136231 IGF2BP3 breast cancer 29847788
ENSG00000136231 IGF2BP3 HNSCC 30243807
ENSG00000136231 IGF2BP3 tumours 30423315
ENSG00000136231 IGF2BP3 liver cancers 30670575
ENSG00000136231 IGF2BP3 tumors 30760837
ENSG00000136231 IGF2BP3 breast cancer 30797711
ENSG00000136231 IGF2BP3 colorectal cancer 30895618
ENSG00000136231 IGF2BP3 cancer 31309275
ENSG00000136231 IGF2BP3 tumor 31440515
ENSG00000136231 IGF2BP3 tumors 31571332
ENSG00000136231 IGF2BP3 non-small-cell lung cancer 31611984
ENSG00000136231 IGF2BP3 breast cancer 31701672
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000136231 IGF2BP3 SARC 0.00019 high
ENSG00000136231 IGF2BP3 UVM 0.00089 high
ENSG00000136231 IGF2BP3 UCEC 0.0043 high
ENSG00000136231 IGF2BP3 THCA 0.00019 high
ENSG00000136231 IGF2BP3 ACC 0.00012 high
ENSG00000136231 IGF2BP3 LUSC 0.044 low
ENSG00000136231 IGF2BP3 HNSC 0.024 high
ENSG00000136231 IGF2BP3 KICH 0.017 high
ENSG00000136231 IGF2BP3 LUAD 0.0012 high
ENSG00000136231 IGF2BP3 PCPG 0.0021 high
ENSG00000136231 IGF2BP3 BRCA 0.036 high
ENSG00000136231 IGF2BP3 BLCA 0.0035 high
ENSG00000136231 IGF2BP3 LAML 0.00011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000136231 IGF2BP3 OV Del 1.661234 0.196149 0.603525 0.295337