Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq DataSet_01_2

Description

Ensembl ID ENSG00000135250 Gene ID 6733 Accession 11306
Symbol SRPK2 Alias SFRSK2 Full Name SRSF protein kinase 2
Status Confidence Length 274643 bases Strand Minus strand
Position 7 : 105114749 - 105389391 RNA binding domain N.A.
Summary Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including nucleic acid metabolic process; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
29153836 Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Gina Lee 2017-12-14 Cell
18559500 Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1. Sung-Wuk Jang 2008-06-15 Cancer research
36096767 An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer. Bryan McClellan 2022-09-12 BMC cancer
28826672 Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease. Zhi-Hao Wang 2017-09-07 Molecular cell
37202390 FBXW7β loss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth. Wenxia Wei 2023-05-19 Signal transduction and targeted therapy
31796646 HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway. Jianxu Chen 2019-12-04 Aging

Transcripts

Name Transcript ID bp Protein Translation ID
SRPK2-215 ENST00000493638 715 No protein -
SRPK2-210 ENST00000477925 5271 588aa ENSP00000420208
SRPK2-205 ENST00000465072 954 147aa ENSP00000417946
SRPK2-211 ENST00000482862 4381 725aa ENSP00000516319
SRPK2-203 ENST00000460391 4004 719aa ENSP00000417357
SRPK2-202 ENST00000393651 3679 699aa ENSP00000377262
SRPK2-201 ENST00000357311 3700 688aa ENSP00000349863
SRPK2-212 ENST00000482897 3546 37aa ENSP00000419240
SRPK2-207 ENST00000466917 2565 No protein -
SRPK2-213 ENST00000485455 436 No protein -
SRPK2-214 ENST00000489828 2560 688aa ENSP00000419791
SRPK2-208 ENST00000474770 872 204aa ENSP00000418786
SRPK2-209 ENST00000476117 703 No protein -
SRPK2-204 ENST00000462282 505 No protein -
SRPK2-206 ENST00000465112 568 68aa ENSP00000417446

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
22727Anthropometry2.1820000E-005-
22738Anthropometry2.0820000E-005-
22744Anthropometry3.6540000E-006-
22789Anthropometry6.4370000E-005-
22793Anthropometry6.4370000E-005-
24980Waist Circumference7.9640000E-005-
24993Waist Circumference2.6980000E-005-
28189Insulin Resistance8.1800000E-005-
28794monocyte chemoattractant protein 1 (66-77)4.4270000E-005-
28828monocyte chemoattractant protein 1 (66-77)9.6000000E-005-
28868monocyte chemoattractant protein 1 (66-77)3.1840000E-005-
80261Schizophrenia1E-926198764
88089Emotions9E-627089181
92653Macular Degeneration1E-926691988
92654Wet Macular Degeneration1E-926691988
93637Body Mass Index3E-825673412
93638Waist Circumference3E-825673412
97152Schizophrenia1E-925056061
97453Myopia, Degenerative2E-723049088

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135250homo_sapiensENSP0000021565941.961926.703homo_sapiensENSP0000037726222.031514.02
ENSG00000135250homo_sapiensENSP0000037896819.485312.0098homo_sapiensENSP0000037726222.746814.02
ENSG00000135250homo_sapiensENSP0000033368543.406627.4725homo_sapiensENSP0000037726222.603714.3062
ENSG00000135250homo_sapiensENSP0000034648422.685213.7346homo_sapiensENSP0000037726221.0312.7325
ENSG00000135250homo_sapiensENSP0000050169223.575914.8734homo_sapiensENSP0000037726221.316213.4478
ENSG00000135250homo_sapiensENSP0000026184519.556211.6505homo_sapiensENSP0000037726220.171712.0172
ENSG00000135250homo_sapiensENSP0000033769125.551516.1765homo_sapiensENSP0000037726219.885612.5894
ENSG00000135250homo_sapiensENSP0000035530432.935618.1384homo_sapiensENSP0000037726219.742510.8727
ENSG00000135250homo_sapiensENSP0000038462527.893718.5958homo_sapiensENSP0000037726221.0314.02
ENSG00000135250homo_sapiensENSP0000038323423.33914.1397homo_sapiensENSP0000037726219.599411.8741
ENSG00000135250homo_sapiensENSP0000036330434.894622.9508homo_sapiensENSP0000037726221.316214.02
ENSG00000135250homo_sapiensENSP0000049343532.112121.1207homo_sapiensENSP0000037726221.316214.02
ENSG00000135250homo_sapiensENSP0000026302540.105525.5937homo_sapiensENSP0000037726221.745313.877
ENSG00000135250homo_sapiensENSP0000021583240.833325.5556homo_sapiensENSP0000037726221.0313.1617
ENSG00000135250homo_sapiensENSP0000022979442.777826.9444homo_sapiensENSP0000037726222.031513.877
ENSG00000135250homo_sapiensENSP0000036293172.824460.458homo_sapiensENSP0000037726268.240356.6524
ENSG00000135250homo_sapiensENSP0000021128741.369926.0274homo_sapiensENSP0000037726221.602313.5908
ENSG00000135250homo_sapiensENSP0000035911974.250463.6684homo_sapiensENSP0000037726260.228951.6452
ENSG00000135250homo_sapiensENSP0000039456035.141522.8774homo_sapiensENSP0000037726221.316213.877

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000135250homo_sapiensENSP0000037726297.138896.1373nomascus_leucogenysENSNLEP0000001098998.835597.8166
ENSG00000135250homo_sapiensENSP0000037726297.424996.5665pan_paniscusENSPPAP0000000136299.126698.2533
ENSG00000135250homo_sapiensENSP0000037726299.570899.4278pongo_abeliiENSPPYP0000002005499.713599.5702
ENSG00000135250homo_sapiensENSP0000037726299.856999.8569pan_troglodytesENSPTRP00000087950100100
ENSG00000135250homo_sapiensENSP0000037726297.424996.5665gorilla_gorillaENSGGOP0000002353299.126698.2533
ENSG00000135250homo_sapiensENSP0000037726293.13389.2704ornithorhynchus_anatinusENSOANP0000004859388.934485.2459
ENSG00000135250homo_sapiensENSP0000037726294.563790.1288sarcophilus_harrisiiENSSHAP0000000583484.526980.5627
ENSG00000135250homo_sapiensENSP0000037726259.799758.226notamacropus_eugeniiENSMEUP0000000340662.202460.5655
ENSG00000135250homo_sapiensENSP0000037726287.696786.2661choloepus_hoffmanniENSCHOP0000000057391.766590.2695
ENSG00000135250homo_sapiensENSP0000037726294.706793.8484dasypus_novemcinctusENSDNOP0000000553396.642395.7664
ENSG00000135250homo_sapiensENSP0000037726289.699688.8412erinaceus_europaeusENSEEUP0000001168193.026792.1365
ENSG00000135250homo_sapiensENSP0000037726283.69180.9728echinops_telfairiENSETEP0000001492487.053684.2262
ENSG00000135250homo_sapiensENSP0000037726296.566594.7067callithrix_jacchusENSCJAP0000002959088.932887.22
ENSG00000135250homo_sapiensENSP0000037726299.713999.4278cercocebus_atysENSCATP0000003385499.856799.5702
ENSG00000135250homo_sapiensENSP0000037726297.71196.4235macaca_fascicularisENSMFAP0000006116475.220374.2291
ENSG00000135250homo_sapiensENSP0000037726297.854196.4235macaca_mulattaENSMMUP0000006608474.347873.2609
ENSG00000135250homo_sapiensENSP0000037726297.281896.2804macaca_nemestrinaENSMNEP0000002137298.981197.9622
ENSG00000135250homo_sapiensENSP0000037726299.713999.5708papio_anubisENSPANP0000001217299.856799.7135
ENSG00000135250homo_sapiensENSP0000037726297.281895.9943mandrillus_leucophaeusENSMLEP0000002275898.981197.671
ENSG00000135250homo_sapiensENSP0000037726293.13392.1316tursiops_truncatusENSTTRP0000000139094.211393.1983
ENSG00000135250homo_sapiensENSP0000037726293.705392.8469vulpes_vulpesENSVVUP0000001965491.994491.1517
ENSG00000135250homo_sapiensENSP0000037726293.276190.701mus_spretusMGP_SPRETEiJ_P006948195.741693.0984
ENSG00000135250homo_sapiensENSP0000037726293.848493.2761equus_asinusENSEASP0000502553493.049692.4823
ENSG00000135250homo_sapiensENSP0000037726296.709695.9943capra_hircusENSCHIP0000002748096.987196.2697
ENSG00000135250homo_sapiensENSP0000037726294.277592.99loxodonta_africanaENSLAFP0000000365997.774596.4392
ENSG00000135250homo_sapiensENSP0000037726294.277592.4177panthera_leoENSPLOP0000001032291.910790.0976
ENSG00000135250homo_sapiensENSP0000037726294.706792.99ailuropoda_melanoleucaENSAMEP0000004055892.329190.6555
ENSG00000135250homo_sapiensENSP0000037726295.42293.5622bos_indicus_hybridENSBIXP0000504389088.461586.7374
ENSG00000135250homo_sapiensENSP0000037726295.851294.1345oryctolagus_cuniculusENSOCUP0000000583490.663189.0392
ENSG00000135250homo_sapiensENSP0000037726296.566595.7082equus_caballusENSECAP0000000871188.005287.2229
ENSG00000135250homo_sapiensENSP0000037726294.563792.8469canis_lupus_familiarisENSCAFP0084503903892.189790.516
ENSG00000135250homo_sapiensENSP0000037726295.851294.8498panthera_pardusENSPPRP0000002708296.960995.9479
ENSG00000135250homo_sapiensENSP0000037726295.994394.1345marmota_marmota_marmotaENSMMMP0000001908197.67195.7787
ENSG00000135250homo_sapiensENSP0000037726295.135992.4177balaenoptera_musculusENSBMSP0001000839089.022886.4792
ENSG00000135250homo_sapiensENSP0000037726294.563791.2732cavia_porcellusENSCPOP0000000121196.075692.7326
ENSG00000135250homo_sapiensENSP0000037726294.849892.7039felis_catusENSFCAP0000003271187.93185.9416
ENSG00000135250homo_sapiensENSP0000037726281.40280.5436ursus_americanusENSUAMP0000002707396.768795.7483
ENSG00000135250homo_sapiensENSP0000037726288.41284.5494monodelphis_domesticaENSMODP0000005548892.653788.6057
ENSG00000135250homo_sapiensENSP0000037726229.041528.6123monodelphis_domesticaENSMODP0000004299695.754794.3396
ENSG00000135250homo_sapiensENSP0000037726296.709695.9943bison_bison_bisonENSBBBP0000000735396.709695.9943
ENSG00000135250homo_sapiensENSP0000037726297.138896.1373monodon_monocerosENSMMNP0001500878397.417596.4132
ENSG00000135250homo_sapiensENSP0000037726296.709694.4206sus_scrofaENSSSCP0000003926792.098189.9183
ENSG00000135250homo_sapiensENSP0000037726281.258976.3949microcebus_murinusENSMICP0000001899889.308283.9623
ENSG00000135250homo_sapiensENSP0000037726226.466426.4664octodon_degusENSODEP0000000270598.404398.4043
ENSG00000135250homo_sapiensENSP0000037726222.889822.4607octodon_degusENSODEP0000000258598.159596.319
ENSG00000135250homo_sapiensENSP0000037726295.565193.5622jaculus_jaculusENSJJAP0000000100797.376195.3353
ENSG00000135250homo_sapiensENSP0000037726296.566595.8512ovis_aries_rambouilletENSOARP0002001108875.41974.8603
ENSG00000135250homo_sapiensENSP0000037726294.420692.7039ursus_maritimusENSUMAP0000002549992.050290.3766
ENSG00000135250homo_sapiensENSP0000037726264.806964.5207ochotona_princepsENSOPRP0000001413967.511267.2131
ENSG00000135250homo_sapiensENSP0000037726297.281896.1373delphinapterus_leucasENSDLEP0000000056192.643191.5531
ENSG00000135250homo_sapiensENSP0000037726295.994393.5622physeter_catodonENSPCTP0000500419486.246884.0617
ENSG00000135250homo_sapiensENSP0000037726293.562290.9871mus_caroliMGP_CAROLIEiJ_P006686196.035293.3921
ENSG00000135250homo_sapiensENSP0000037726293.419290.9871mus_musculusENSMUSP0000008573495.747893.2551
ENSG00000135250homo_sapiensENSP0000037726226.466426.3233dipodomys_ordiiENSDORP0000000218898.930598.3957
ENSG00000135250homo_sapiensENSP0000037726223.032922.7468dipodomys_ordiiENSDORP0000002334294.15292.9825
ENSG00000135250homo_sapiensENSP0000037726294.277592.4177mustela_putorius_furoENSMPUP0000001814696.064194.1691
ENSG00000135250homo_sapiensENSP0000037726296.852695.5651aotus_nancymaaeENSANAP0000001705698.544497.2344
ENSG00000135250homo_sapiensENSP0000037726295.708293.7053saimiri_boliviensis_boliviensisENSSBOP0000000168196.816294.7902
ENSG00000135250homo_sapiensENSP0000037726286.12385.2647vicugna_pacosENSVPAP0000000830892.901291.9753
ENSG00000135250homo_sapiensENSP0000037726297.56896.4235chlorocebus_sabaeusENSCSAP0000000774297.15196.0114
ENSG00000135250homo_sapiensENSP0000037726279.685378.6838tupaia_belangeriENSTBEP0000000086182.518581.4815
ENSG00000135250homo_sapiensENSP0000037726293.419290.8441mesocricetus_auratusENSMAUP0000000810595.607692.9722
ENSG00000135250homo_sapiensENSP0000037726295.135992.99phocoena_sinusENSPSNP0000003129992.747690.6555
ENSG00000135250homo_sapiensENSP0000037726295.708293.8484camelus_dromedariusENSCDRP0000501358392.916791.1111
ENSG00000135250homo_sapiensENSP0000037726298.712497.568carlito_syrichtaENSTSYP0000000305298.995797.8479
ENSG00000135250homo_sapiensENSP0000037726294.563792.7039panthera_tigris_altaicaENSPTIP0000002177294.971393.1034
ENSG00000135250homo_sapiensENSP0000037726291.988689.8426rattus_norvegicusENSRNOP0000007014989.181787.1012
ENSG00000135250homo_sapiensENSP0000037726298.712497.8541prolemur_simusENSPSMP0000002255298.853997.9943
ENSG00000135250homo_sapiensENSP0000037726293.562291.5594microtus_ochrogasterENSMOCP0000001897595.894493.8416
ENSG00000135250homo_sapiensENSP0000037726281.545179.3991sorex_araneusENSSARP0000001170084.695482.4666
ENSG00000135250homo_sapiensENSP0000037726294.134591.9886peromyscus_maniculatus_bairdiiENSPEMP0000002777496.339794.1435
ENSG00000135250homo_sapiensENSP0000037726296.852695.8512bos_mutusENSBMUP0000001102188.496787.5817
ENSG00000135250homo_sapiensENSP0000037726293.562290.2718mus_spicilegusENSMSIP0000003019288.259185.1552
ENSG00000135250homo_sapiensENSP0000037726292.9990.5579cricetulus_griseus_chok1gshdENSCGRP0000102369395.307992.8152
ENSG00000135250homo_sapiensENSP0000037726289.413488.1259pteropus_vampyrusENSPVAP0000000347685.969784.7318
ENSG00000135250homo_sapiensENSP0000037726294.706793.4192myotis_lucifugusENSMLUP0000000246695.803294.5007
ENSG00000135250homo_sapiensENSP0000037726295.708292.7039vombatus_ursinusENSVURP0001001432695.982892.9699
ENSG00000135250homo_sapiensENSP0000037726297.71196.4235rhinolophus_ferrumequinumENSRFEP0001002370793.6992.4554
ENSG00000135250homo_sapiensENSP0000037726292.703990.8441neovison_visonENSNVIP0000002100294.598592.7007
ENSG00000135250homo_sapiensENSP0000037726296.852695.9943bos_taurusENSBTAP0000007355288.496787.7124
ENSG00000135250homo_sapiensENSP0000037726295.994393.133heterocephalus_glaber_femaleENSHGLP0000005282588.99286.3395
ENSG00000135250homo_sapiensENSP0000037726296.852695.8512rhinopithecus_bietiENSRBIP0000001043098.832197.8102
ENSG00000135250homo_sapiensENSP0000037726221.316220.7439canis_lupus_dingoENSCAFP0002002958397.385694.7712
ENSG00000135250homo_sapiensENSP0000037726216.738216.4521canis_lupus_dingoENSCAFP0002002956278.523577.1812
ENSG00000135250homo_sapiensENSP0000037726298.426397.2818sciurus_vulgarisENSSVLP0000502987398.567397.4212
ENSG00000135250homo_sapiensENSP0000037726294.420690.1288phascolarctos_cinereusENSPCIP0000001775190.163986.0656
ENSG00000135250homo_sapiensENSP0000037726280.400678.97procavia_capensisENSPCAP0000001322183.506782.0208
ENSG00000135250homo_sapiensENSP0000037726294.706792.8469nannospalax_galiliENSNGAP0000002628196.220994.3314
ENSG00000135250homo_sapiensENSP0000037726294.849893.2761bos_grunniensENSBGRP0000001433092.468690.9344
ENSG00000135250homo_sapiensENSP0000037726295.42293.2761chinchilla_lanigeraENSCLAP0000001725597.088894.9054
ENSG00000135250homo_sapiensENSP0000037726296.852695.9943cervus_hanglu_yarkandensisENSCHYP0000003982188.496787.7124
ENSG00000135250homo_sapiensENSP0000037726297.424995.9943catagonus_wagneriENSCWAP0000002477797.704496.2697
ENSG00000135250homo_sapiensENSP0000037726287.410685.5508ictidomys_tridecemlineatusENSSTOP0000000864097.448295.3748
ENSG00000135250homo_sapiensENSP0000037726295.135994.1345otolemur_garnettiiENSOGAP0000000254198.227597.1935
ENSG00000135250homo_sapiensENSP0000037726299.284798.8555cebus_imitatorENSCCAP0000001659199.426998.9971
ENSG00000135250homo_sapiensENSP0000037726298.426397.4249urocitellus_parryiiENSUPAP0001001693694.375993.4156
ENSG00000135250homo_sapiensENSP0000037726295.27993.2761moschus_moschiferusENSMMSP0000001956792.590.5556
ENSG00000135250homo_sapiensENSP0000037726297.138896.1373rhinopithecus_roxellanaENSRROP0000004080898.835597.8166
ENSG00000135250homo_sapiensENSP0000037726293.13390.701mus_pahariMGP_PahariEiJ_P004831195.594793.0984
ENSG00000135250homo_sapiensENSP0000037726298.855598.1402propithecus_coquereliENSPCOP0000002547998.997198.2808
ENSG00000135250homo_sapiensENSP0000037726221.0312.8755caenorhabditis_elegansB0218.3.138.99223.8727
ENSG00000135250homo_sapiensENSP0000037726221.888413.1617caenorhabditis_elegansF42G8.3a.138.059722.8856
ENSG00000135250homo_sapiensENSP0000037726221.745314.02caenorhabditis_elegansW06F12.1a.123.974815.4574
ENSG00000135250homo_sapiensENSP0000037726253.075842.9185caenorhabditis_elegansB0464.5a.136.98929.9103
ENSG00000135250homo_sapiensENSP0000037726219.742512.1602caenorhabditis_elegansT07A9.3.235.384621.7949
ENSG00000135250homo_sapiensENSP0000037726219.313312.3033caenorhabditis_elegansZC416.4.140.662725.9036
ENSG00000135250homo_sapiensENSP0000037726220.600911.588caenorhabditis_elegansC36B1.10.137.795321.2598
ENSG00000135250homo_sapiensENSP0000037726220.314711.731caenorhabditis_elegansY106G6E.1.137.270321.5223
ENSG00000135250homo_sapiensENSP0000037726219.885613.1617drosophila_melanogasterFBpp042315531.662920.9567
ENSG00000135250homo_sapiensENSP0000037726247.210333.9056drosophila_melanogasterFBpp007391741.772230
ENSG00000135250homo_sapiensENSP0000037726258.941346.3519drosophila_melanogasterFBpp042815740.832532.111
ENSG00000135250homo_sapiensENSP0000037726218.168811.3019ciona_intestinalisENSCINP0000001100931.513619.603
ENSG00000135250homo_sapiensENSP0000037726232.331930.0429petromyzon_marinusENSPMAP0000000657289.328183.004
ENSG00000135250homo_sapiensENSP0000037726276.82465.093eptatretus_burgeriENSEBUP0000002789230.826626.1194
ENSG00000135250homo_sapiensENSP0000037726286.266178.5408callorhinchus_miliiENSCMIP0000003218086.637978.8793
ENSG00000135250homo_sapiensENSP0000037726282.546574.6781latimeria_chalumnaeENSLACP0000001857684.356776.3158
ENSG00000135250homo_sapiensENSP0000037726249.928543.9199lepisosteus_oculatusENSLOCP0000001906061.228153.8596
ENSG00000135250homo_sapiensENSP0000037726222.603719.5994clupea_harengusENSCHAP0000001829768.695759.5652
ENSG00000135250homo_sapiensENSP0000037726244.349139.0558clupea_harengusENSCHAP0000001836847.184241.5525
ENSG00000135250homo_sapiensENSP0000037726221.0320.1717danio_rerioENSDARP0000015116091.87588.125
ENSG00000135250homo_sapiensENSP0000037726221.173120.1717danio_rerioENSDARP0000015338292.588.125
ENSG00000135250homo_sapiensENSP0000037726216.452115.8798danio_rerioENSDARP0000015343971.428668.9441
ENSG00000135250homo_sapiensENSP0000037726277.253271.2446carassius_auratusENSCARP0000009717664.516159.4982
ENSG00000135250homo_sapiensENSP0000037726265.951458.9413astyanax_mexicanusENSAMXP0000001485571.032463.4823
ENSG00000135250homo_sapiensENSP0000037726276.394969.814ictalurus_punctatusENSIPUP0000002262564.259958.7244
ENSG00000135250homo_sapiensENSP0000037726275.536566.8097esox_luciusENSELUP0000005676657.704951.0382
ENSG00000135250homo_sapiensENSP0000037726275.679569.0987electrophorus_electricusENSEEEP0000004138177.679970.9251
ENSG00000135250homo_sapiensENSP0000037726279.542271.3877oncorhynchus_kisutchENSOKIP0000500970263.90857.3563
ENSG00000135250homo_sapiensENSP0000037726278.540869.2418oncorhynchus_kisutchENSOKIP0000506382960.197453.0702
ENSG00000135250homo_sapiensENSP0000037726279.11371.1016oncorhynchus_mykissENSOMYP0000002831864.227657.7236
ENSG00000135250homo_sapiensENSP0000037726266.094458.9413oncorhynchus_mykissENSOMYP0000014073858.703952.3507
ENSG00000135250homo_sapiensENSP0000037726279.542271.1016salmo_salarENSSSAP0000004568962.824956.1582
ENSG00000135250homo_sapiensENSP0000037726279.542271.3877salmo_salarENSSSAP0000007280264.055357.4885
ENSG00000135250homo_sapiensENSP0000037726280.114471.9599salmo_truttaENSSTUP0000001570464.367857.8161
ENSG00000135250homo_sapiensENSP0000037726280.972872.8183salmo_truttaENSSTUP0000006449962.749456.4302
ENSG00000135250homo_sapiensENSP0000037726274.821267.0958gadus_morhuaENSGMOP0000004265947.71942.792
ENSG00000135250homo_sapiensENSP0000037726277.396369.3848fundulus_heteroclitusENSFHEP0000003197260.514554.2506
ENSG00000135250homo_sapiensENSP0000037726210.15749.15594poecilia_reticulataENSPREP0000002829454.615449.2308
ENSG00000135250homo_sapiensENSP0000037726222.460721.1731poecilia_reticulataENSPREP0000002827793.452488.0952
ENSG00000135250homo_sapiensENSP0000037726278.397770.1001xiphophorus_maculatusENSXMAP0000003546360.41954.0243
ENSG00000135250homo_sapiensENSP0000037726277.825569.3848oryzias_latipesENSORLP0000002982963.477256.5928
ENSG00000135250homo_sapiensENSP0000037726270.958564.2346cyclopterus_lumpusENSCLMP0000503923471.366964.6043
ENSG00000135250homo_sapiensENSP0000037726267.954262.6609oreochromis_niloticusENSONIP0000003430567.567662.3044
ENSG00000135250homo_sapiensENSP0000037726280.972874.2489haplochromis_burtoniENSHBUP0000001353164.538259.179
ENSG00000135250homo_sapiensENSP0000037726273.676766.9528astatotilapia_callipteraENSACLP0000003919161.01955.4502
ENSG00000135250homo_sapiensENSP0000037726270.100163.9485sparus_aurataENSSAUP0001006679566.485860.6513
ENSG00000135250homo_sapiensENSP0000037726215.736815.5937lates_calcariferENSLCAP0001001716374.829974.1497
ENSG00000135250homo_sapiensENSP0000037726289.127383.1187xenopus_tropicalisENSXETP0000011826684.993279.2633
ENSG00000135250homo_sapiensENSP0000037726285.407781.9743chrysemys_picta_belliiENSCPBP0000001696489.909686.2952
ENSG00000135250homo_sapiensENSP0000037726217.882717.0243sphenodon_punctatusENSSPUP0000002502996.899292.2481
ENSG00000135250homo_sapiensENSP0000037726220.600920.1717sphenodon_punctatusENSSPUP0000002502798.630196.5753
ENSG00000135250homo_sapiensENSP0000037726215.593714.5923sphenodon_punctatusENSSPUP0000002503172.666768
ENSG00000135250homo_sapiensENSP0000037726292.560888.9843crocodylus_porosusENSCPRP0000502028287.196883.8275
ENSG00000135250homo_sapiensENSP0000037726271.387765.3791laticauda_laticaudataENSLLTP0000002042472.953266.8129
ENSG00000135250homo_sapiensENSP0000037726281.115976.1087notechis_scutatusENSNSUP0000000211478.423273.5823
ENSG00000135250homo_sapiensENSP0000037726293.562287.8398pseudonaja_textilisENSPTXP0000001710388.140282.7493
ENSG00000135250homo_sapiensENSP0000037726292.9989.2704anas_platyrhynchos_platyrhynchosENSAPLP0000002986488.075984.5528
ENSG00000135250homo_sapiensENSP0000037726288.698184.8355gallus_gallusENSGALP0001001373885.872682.133
ENSG00000135250homo_sapiensENSP0000037726265.951462.6609meleagris_gallopavoENSMGAP0000000674788.145383.7476
ENSG00000135250homo_sapiensENSP0000037726292.131688.269serinus_canariaENSSCAP0000000969889.944186.1732
ENSG00000135250homo_sapiensENSP0000037726292.417788.412parus_majorENSPMJP0000000525489.84785.9527
ENSG00000135250homo_sapiensENSP0000037726293.848488.8412anolis_carolinensisENSACAP0000000700792.134887.2191
ENSG00000135250homo_sapiensENSP0000037726265.236159.9428neolamprologus_brichardiENSNBRP0000002486568.986463.3888
ENSG00000135250homo_sapiensENSP0000037726293.562287.6967naja_najaENSNNAP0000002724188.259182.726
ENSG00000135250homo_sapiensENSP0000037726291.416385.5508podarcis_muralisENSPMRP0000001981492.743186.7924
ENSG00000135250homo_sapiensENSP0000037726280.400676.681geospiza_fortisENSGFOP0000000021395.254290.8475
ENSG00000135250homo_sapiensENSP0000037726292.560888.269taeniopygia_guttataENSTGUP0000002616674.97171.4948
ENSG00000135250homo_sapiensENSP0000037726283.83476.824erpetoichthys_calabaricusENSECRP0000000285576.103969.7403
ENSG00000135250homo_sapiensENSP0000037726265.808361.0873kryptolebias_marmoratusENSKMAP0000001778369.486464.5015
ENSG00000135250homo_sapiensENSP0000037726293.562287.9828salvator_merianaeENSSMRP0000002090392.242686.7419
ENSG00000135250homo_sapiensENSP0000037726275.679567.525oryzias_javanicusENSOJAP0000001780460.18253.6974
ENSG00000135250homo_sapiensENSP0000037726215.879815.5937amphilophus_citrinellusENSACIP0000002442373.509972.1854
ENSG00000135250homo_sapiensENSP0000037726220.600919.7425amphilophus_citrinellusENSACIP0000002445194.736890.7895
ENSG00000135250homo_sapiensENSP0000037726271.530865.2361dicentrarchus_labraxENSDLAP0000505067069.73563.5983
ENSG00000135250homo_sapiensENSP0000037726266.094460.372amphiprion_perculaENSAPEP0000001004161.273255.9682
ENSG00000135250homo_sapiensENSP0000037726269.384862.804oryzias_sinensisENSOSIP0000000383666.98960.6354
ENSG00000135250homo_sapiensENSP0000037726292.703988.269pelodiscus_sinensisENSPSIP0000000413487.096882.9301
ENSG00000135250homo_sapiensENSP0000037726291.130287.4106gopherus_evgoodeiENSGEVP0000500350189.971786.2994
ENSG00000135250homo_sapiensENSP0000037726287.267583.1187chelonoidis_abingdoniiENSCABP0000000052581.769477.882
ENSG00000135250homo_sapiensENSP0000037726279.828372.3891seriola_dumeriliENSSDUP0000003236662.696656.8539
ENSG00000135250homo_sapiensENSP0000037726252.789750.6438cottoperca_gobioENSCGOP0000005090180.043476.7896
ENSG00000135250homo_sapiensENSP0000037726289.985785.2647struthio_camelus_australisENSSCUP0000001176986.998682.4343
ENSG00000135250homo_sapiensENSP0000037726292.9989.2704anser_brachyrhynchusENSABRP0000000502488.075984.5528
ENSG00000135250homo_sapiensENSP0000037726239.914237.0529gasterosteus_aculeatusENSGACP0000000502975.609870.1897
ENSG00000135250homo_sapiensENSP0000037726276.537969.814cynoglossus_semilaevisENSCSEP0000001464161.212855.8352
ENSG00000135250homo_sapiensENSP0000037726274.105967.8112poecilia_formosaENSPFOP0000001154073.894467.6177
ENSG00000135250homo_sapiensENSP0000037726215.593715.3076myripristis_murdjanENSMMDP0000502517874.149772.7891
ENSG00000135250homo_sapiensENSP0000037726223.31921.3162myripristis_murdjanENSMMDP0000502517491.57383.7079
ENSG00000135250homo_sapiensENSP0000037726277.682469.3848sander_luciopercaENSSLUP0000003093461.217654.6787
ENSG00000135250homo_sapiensENSP0000037726292.9988.8412strigops_habroptilaENSSHBP0000501286791.678487.5882
ENSG00000135250homo_sapiensENSP0000037726280.400672.6752amphiprion_ocellarisENSAOCP0000002547264.228658.0571
ENSG00000135250homo_sapiensENSP0000037726285.407781.8312terrapene_carolina_triunguisENSTMTP0000000553688.313684.6154
ENSG00000135250homo_sapiensENSP0000037726267.52561.5165hucho_huchoENSHHUP0000004040866.478960.5634
ENSG00000135250homo_sapiensENSP0000037726261.373454.9356hucho_huchoENSHHUP0000000840459.832653.5565
ENSG00000135250homo_sapiensENSP0000037726279.11372.9614betta_splendensENSBSLP0000005508760.174155.4951
ENSG00000135250homo_sapiensENSP0000037726215.593715.3076pygocentrus_nattereriENSPNAP0000001165973.648772.2973
ENSG00000135250homo_sapiensENSP0000037726279.828373.8197anabas_testudineusENSATEP0000005130362.48657.7828
ENSG00000135250homo_sapiensENSP0000037726218.025811.1588ciona_savignyiENSCSAVP0000001240731.343319.403
ENSG00000135250homo_sapiensENSP0000037726247.210334.0486saccharomyces_cerevisiaeYMR216C44.474432.0755
ENSG00000135250homo_sapiensENSP0000037726221.459212.4464saccharomyces_cerevisiaeYKL161C34.64220.0924
ENSG00000135250homo_sapiensENSP0000037726222.031512.8755saccharomyces_cerevisiaeYHR030C31.818218.595
ENSG00000135250homo_sapiensENSP0000037726270.100164.9499seriola_lalandi_dorsalisENSSLDP0000003083871.637466.3743
ENSG00000135250homo_sapiensENSP0000037726257.081554.2203labrus_bergyltaENSLBEP0000003034787.117982.7511
ENSG00000135250homo_sapiensENSP0000037726270.815565.8083pundamilia_nyerereiENSPNYP0000000902571.325666.2824
ENSG00000135250homo_sapiensENSP0000037726280.257572.5322mastacembelus_armatusENSMAMP0000003445164.780658.545
ENSG00000135250homo_sapiensENSP0000037726278.397770.6724stegastes_partitusENSSPAP0000001651162.557156.3927
ENSG00000135250homo_sapiensENSP0000037726277.825569.3848oncorhynchus_tshawytschaENSOTSP0000504137063.774956.8581
ENSG00000135250homo_sapiensENSP0000037726235.765425.465oncorhynchus_tshawytschaENSOTSP0000505135649.309735.1085
ENSG00000135250homo_sapiensENSP0000037726212.589411.3019oncorhynchus_tshawytschaENSOTSP0000505135781.481573.1481
ENSG00000135250homo_sapiensENSP0000037726265.951460.2289acanthochromis_polyacanthusENSAPOP0000002544260.657955.3947
ENSG00000135250homo_sapiensENSP0000037726292.9988.9843aquila_chrysaetos_chrysaetosENSACCP0002001283289.655285.7931
ENSG00000135250homo_sapiensENSP0000037726278.9771.9599nothobranchius_furzeriENSNFUP0001504514862.022556.5169
ENSG00000135250homo_sapiensENSP0000037726278.111669.0987cyprinodon_variegatusENSCVAP0000000825161.417354.3307
ENSG00000135250homo_sapiensENSP0000037726265.522259.0844denticeps_clupeoidesENSDCDP0000005138163.522957.2816
ENSG00000135250homo_sapiensENSP0000037726281.115973.9628larimichthys_croceaENSLCRP0000503106562.171156.6886
ENSG00000135250homo_sapiensENSP0000037726279.399171.5308takifugu_rubripesENSTRUP0000007626860.195254.2299
ENSG00000135250homo_sapiensENSP0000037726287.124582.5465ficedula_albicollisENSFALP0000001077189.82385.1032
ENSG00000135250homo_sapiensENSP0000037726215.593715.4506hippocampus_comesENSHCOP0000000393974.149773.4694
ENSG00000135250homo_sapiensENSP0000037726222.460720.6009hippocampus_comesENSHCOP0000001977088.202280.8989
ENSG00000135250homo_sapiensENSP0000037726273.247566.9528cyprinus_carpio_carpioENSCCRP0000012533560.952455.7143
ENSG00000135250homo_sapiensENSP0000037726276.82470.2432cyprinus_carpio_carpioENSCCRP0000014082751.535547.1209
ENSG00000135250homo_sapiensENSP0000037726292.846988.6981coturnix_japonicaENSCJPP0000500703886.303282.4468
ENSG00000135250homo_sapiensENSP0000037726278.683870.3863poecilia_latipinnaENSPLAP0000001193363.001156.3574
ENSG00000135250homo_sapiensENSP0000037726214.449214.3062sinocyclocheilus_grahamiENSSGRP0000001891872.661971.9424
ENSG00000135250homo_sapiensENSP0000037726275.822668.9557sinocyclocheilus_grahamiENSSGRP0000007290167.515961.4013
ENSG00000135250homo_sapiensENSP0000037726212.446412.0172sinocyclocheilus_grahamiENSSGRP0000005259893.548490.3226
ENSG00000135250homo_sapiensENSP0000037726217.739616.5951sinocyclocheilus_grahamiENSSGRP0000001891993.233187.218
ENSG00000135250homo_sapiensENSP0000037726280.114472.6752maylandia_zebraENSMZEP0000501230563.926957.9909
ENSG00000135250homo_sapiensENSP0000037726269.81462.6609tetraodon_nigroviridisENSTNIP0000000852871.764764.4118
ENSG00000135250homo_sapiensENSP0000037726277.539369.9571paramormyrops_kingsleyaeENSPKIP0000002357069.132762.3724
ENSG00000135250homo_sapiensENSP0000037726268.812661.3734paramormyrops_kingsleyaeENSPKIP0000000518660.12553.625
ENSG00000135250homo_sapiensENSP0000037726277.682471.9599scleropages_formosusENSSFOP0001500996568.130563.1117
ENSG00000135250homo_sapiensENSP0000037726278.111670.8155scleropages_formosusENSSFOP0001504226471.46664.7906
ENSG00000135250homo_sapiensENSP0000037726290.271885.1216leptobrachium_leishanenseENSLLEP0000004695779.974775.4119
ENSG00000135250homo_sapiensENSP0000037726280.543672.3891scophthalmus_maximusENSSMAP0000001150863.615857.1751
ENSG00000135250homo_sapiensENSP0000037726278.9771.5308oryzias_melastigmaENSOMEP0000002632760.592854.8847

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000245involved_in spliceosomal complex assembly2IBA,IDAHomo_sapiens(9606)Process
GO:0000287enables magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0001525involved_in angiogenesis1ISSHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity3IBA,IDA,IGIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006468involved_in protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0008284involved_in positive regulation of cell population proliferation1IDAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IDAHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1ISSHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0018105involved_in peptidyl-serine phosphorylation2IBA,IGIHomo_sapiens(9606)Process
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0035063involved_in nuclear speck organization1ISSHomo_sapiens(9606)Process
GO:0035556involved_in intracellular signal transduction2IBA,IDAHomo_sapiens(9606)Process
GO:0043525involved_in positive regulation of neuron apoptotic process1ISSHomo_sapiens(9606)Process
GO:0045070involved_in positive regulation of viral genome replication1IDAHomo_sapiens(9606)Process
GO:0045071involved_in negative regulation of viral genome replication1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1ICHomo_sapiens(9606)Process
GO:0045787involved_in positive regulation of cell cycle1ISSHomo_sapiens(9606)Process
GO:0048024involved_in regulation of mRNA splicing, via spliceosome1TASHomo_sapiens(9606)Process
GO:0050684involved_in regulation of mRNA processing1IBAHomo_sapiens(9606)Process
GO:0062176involved_in R-loop processing1IDAHomo_sapiens(9606)Process
GO:0071889enables 14-3-3 protein binding1ISSHomo_sapiens(9606)Function
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function

Expression