Ensembl ID
ENSG00000135250
Gene ID
6733
Accession
11306
Gene Symbol
SRPK2
Alias
SFRSK2
Full Name
SRSF protein kinase 2
Position
7 : 105114749 - 105389391
Length
274643 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Non-canonical_RBPs
Summary
Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including nucleic acid metabolic process; peptidyl-serine phosphorylation; and regulation of viral genome replication. Located in chromatin; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000135250 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000135250
SRPK2
0.46
8.99e-17
BRCA
ENSG00000135250
SRPK2
0.70
1.12e-20
LUSC
ENSG00000135250
SRPK2
-1.2
8.36e-12
GBM
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000135250
SRPK2
tumors
23071587
ENSG00000135250
SRPK2
cancer
26244849
ENSG00000135250
SRPK2
HNSCC
26853621
ENSG00000135250
SRPK2
colon cancer
27041240
ENSG00000135250
SRPK2
cancers
29283381
ENSG00000135250
SRPK2
tumors
29587239
ENSG00000135250
SRPK2
pancreatic cancer
30724469
ENSG00000135250
SRPK2
cancer
31229549
ENSG00000135250
SRPK2
non-small cell lung cancer
31833327
ENSG00000135250
SRPK2
colorectal cancer
31898732
ENSG00000135250
SRPK2
cancers
31962201
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000135250
SRPK2
MESO
0.00031
high
show
ENSG00000135250
SRPK2
SARC
0.038
high
show
ENSG00000135250
SRPK2
UVM
0.00037
high
show
ENSG00000135250
SRPK2
UCEC
0.017
high
show
ENSG00000135250
SRPK2
THCA
0.036
high
show
ENSG00000135250
SRPK2
KIRP
0.02
high
show
ENSG00000135250
SRPK2
THYM
0.0032
low
show
ENSG00000135250
SRPK2
UCS
0.0038
high
show
ENSG00000135250
SRPK2
OV
0.046
high
show
ENSG00000135250
SRPK2
KIRC
0.024
low
show
ENSG00000135250
SRPK2
TGCT
0.0078
high
show
ENSG00000135250
SRPK2
LAML
0.00011
low
show
ENSG00000135250
SRPK2
SKCM
0.007
low
show
ENSG00000135250
SRPK2
CESC
0.012
high
show
ENSG00000135250
SRPK2
LIHC
0.023
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000135250
SRPK2
LGG
Amp
4.214658
0.090535
0.668434
0.331384
ENSG00000135250
SRPK2
ESCA
Amp
3.520582
0.412671
0.664321
0.527174
ENSG00000135250
SRPK2
HNSC
Amp
3.353170
0.174759
0.545640
0.296935
ENSG00000135250
SRPK2
STAD
Amp
2.309095
0.177691
0.528882
0.408163
ENSG00000135250
SRPK2
UCEC
Del
0.971644
0.051421
0.456828
0.103896
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