Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs tRNA
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000133706 Gene ID 51520 Accession 6512
Symbol LARS1 Alias LRS;LARS;LEUS;LFIS;ILFS1;LEURS;PIG44;RNTLS;HSPC192;hr025Cl Full Name leucyl-tRNA synthetase 1
Status Confidence Length 72131 bases Strand Minus strand
Position 5 : 146110566 - 146182696 RNA binding domain tRNA-synt_1g , tRNA-synt_1e , tRNA-synt_1 , Anticodon_1
Summary This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000501365 tRNA-synt_1g PF09334 1.6e-17 1
ENSP00000501365 tRNA-synt_1g PF09334 1.6e-17 2
ENSP00000501365 Anticodon_1 PF08264 1e-16 3
ENSP00000501365 tRNA-synt_1 PF00133 9.7e-43 4
ENSP00000501400 tRNA-synt_1g PF09334 2e-17 1
ENSP00000501400 tRNA-synt_1g PF09334 2e-17 2
ENSP00000501400 tRNA-synt_1e PF01406 6.8e-06 3
ENSP00000501400 tRNA-synt_1 PF00133 7.9e-40 4
ENSP00000501400 tRNA-synt_1 PF00133 7.9e-40 5
ENSP00000501486 tRNA-synt_1g PF09334 4.2e-17 1
ENSP00000501486 tRNA-synt_1g PF09334 4.2e-17 2
ENSP00000501486 Anticodon_1 PF08264 9.8e-17 3
ENSP00000501486 tRNA-synt_1 PF00133 2.5e-39 4
ENSP00000501486 tRNA-synt_1 PF00133 2.5e-39 5
ENSP00000501435 tRNA-synt_1g PF09334 4.8e-17 1
ENSP00000501435 tRNA-synt_1g PF09334 4.8e-17 2
ENSP00000501435 Anticodon_1 PF08264 1.1e-16 3
ENSP00000501435 tRNA-synt_1 PF00133 6.4e-36 4
ENSP00000501435 tRNA-synt_1 PF00133 6.4e-36 5
ENSP00000501435 tRNA-synt_1 PF00133 6.4e-36 6
ENSP00000501476 tRNA-synt_1g PF09334 4.9e-17 1
ENSP00000501476 tRNA-synt_1g PF09334 4.9e-17 2
ENSP00000501476 Anticodon_1 PF08264 1.1e-16 3
ENSP00000501476 tRNA-synt_1 PF00133 3.1e-39 4
ENSP00000501476 tRNA-synt_1 PF00133 3.1e-39 5
ENSP00000377954 tRNA-synt_1g PF09334 4.9e-17 1
ENSP00000377954 tRNA-synt_1g PF09334 4.9e-17 2
ENSP00000377954 Anticodon_1 PF08264 1.1e-16 3
ENSP00000377954 tRNA-synt_1 PF00133 3.1e-39 4
ENSP00000377954 tRNA-synt_1 PF00133 3.1e-39 5
ENSP00000501478 tRNA-synt_1g PF09334 3.9e-13 1
ENSP00000501478 Anticodon_1 PF08264 8.2e-17 2
ENSP00000501478 tRNA-synt_1 PF00133 8.1e-20 3
ENSP00000501510 tRNA-synt_1g PF09334 5e-13 1
ENSP00000501510 Anticodon_1 PF08264 1e-16 2
ENSP00000501510 tRNA-synt_1 PF00133 3.9e-32 3
ENSP00000426005 tRNA-synt_1g PF09334 5e-13 1
ENSP00000426005 Anticodon_1 PF08264 9.9e-17 2
ENSP00000426005 tRNA-synt_1 PF00133 3.9e-32 3
ENSP00000501434 tRNA-synt_1g PF09334 5e-13 1
ENSP00000501434 Anticodon_1 PF08264 9.9e-17 2
ENSP00000501434 tRNA-synt_1 PF00133 3.9e-32 3
ENSP00000501376 tRNA-synt_1g PF09334 1.9e-12 1
ENSP00000501376 Anticodon_1 PF08264 1e-16 2
ENSP00000501376 tRNA-synt_1 PF00133 1.3e-32 3
ENSP00000501474 tRNA-synt_1g PF09334 2.9e-09 1
ENSP00000501474 Anticodon_1 PF08264 9.1e-17 2
ENSP00000501474 tRNA-synt_1 PF00133 1.8e-26 3
ENSP00000274562 tRNA-synt_1g PF09334 5.6e-07 1
ENSP00000274562 Anticodon_1 PF08264 4.4e-17 2
ENSP00000501381 tRNA-synt_1g PF09334 1.1e-05 1
ENSP00000501381 tRNA-synt_1 PF00133 4e-28 2
ENSP00000501381 tRNA-synt_1 PF00133 4e-28 3
ENSP00000501351 tRNA-synt_1g PF09334 1.4e-05 1
ENSP00000501351 tRNA-synt_1 PF00133 2.2e-32 2
ENSP00000501351 tRNA-synt_1 PF00133 2.2e-32 3

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36789265 aRgus: Multilevel visualization of non-synonymous single nucleotide variants & advanced pathogenicity score modeling for genetic vulnerability assessment. Julian Schröter 2023-01-01 Computational and structural biotechnology journal

Transcripts

Name Transcript ID bp Protein Translation ID
LARS1-215 ENST00000674181 5318 147aa ENSP00000501475
LARS1-230 ENST00000674471 7339 No protein -
LARS1-204 ENST00000506231 9953 No protein -
LARS1-212 ENST00000674158 7182 1049aa ENSP00000501474
LARS1-216 ENST00000674191 6980 1024aa ENSP00000501478
LARS1-223 ENST00000674383 9724 No protein -
LARS1-218 ENST00000674270 7090 1130aa ENSP00000501365
LARS1-227 ENST00000674447 7147 1149aa ENSP00000501376
LARS1-220 ENST00000674290 7202 1164aa ENSP00000501435
LARS1-217 ENST00000674218 9858 No protein -
LARS1-221 ENST00000674309 7157 850aa ENSP00000501400
LARS1-229 ENST00000674467 7264 697aa ENSP00000501351
LARS1-231 ENST00000674479 8108 No protein -
LARS1-213 ENST00000674170 7331 543aa ENSP00000501381
LARS1-214 ENST00000674174 7140 1122aa ENSP00000501434
LARS1-201 ENST00000394434 4760 1176aa ENSP00000377954
LARS1-219 ENST00000674277 4669 1121aa ENSP00000501510
LARS1-224 ENST00000674398 4768 1175aa ENSP00000501476
LARS1-202 ENST00000504323 4156 No protein -
LARS1-208 ENST00000510191 3737 1122aa ENSP00000426005
LARS1-222 ENST00000674310 3647 1112aa ENSP00000501486
LARS1-207 ENST00000508709 633 No protein -
LARS1-210 ENST00000512412 2641 No protein -
LARS1-206 ENST00000508667 707 No protein -
LARS1-205 ENST00000507095 384 No protein -
LARS1-226 ENST00000674417 4783 No protein -
LARS1-225 ENST00000674412 2945 No protein -
LARS1-228 ENST00000674450 2944 No protein -
LARS1-211 ENST00000618084 1954 No protein -
LARS1-209 ENST00000511505 1089 No protein -
LARS1-203 ENST00000505223 2533 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
97370Alzheimer Disease4E-826830138
97371Age of Onset4E-826830138

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000133706homo_sapiensENSP0000050258528.598316.651homo_sapiensENSP0000037795425.850315.051
ENSG00000133706homo_sapiensENSP0000040644826.703614.0254homo_sapiensENSP0000037795428.656515.051
ENSG00000133706homo_sapiensENSP0000028227628.330514.1653homo_sapiensENSP0000037795414.28577.14286
ENSG00000133706homo_sapiensENSP0000026202723.666712.5556homo_sapiensENSP0000037795418.11229.60884
ENSG00000133706homo_sapiensENSP0000049509330.343316.6113homo_sapiensENSP0000037795423.299312.7551
ENSG00000133706homo_sapiensENSP0000036481525.237314.0032homo_sapiensENSP0000037795427.125915.051
ENSG00000133706homo_sapiensENSP0000035588930.731214.9209homo_sapiensENSP0000037795426.445612.8401

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000133706homo_sapiensENSP0000037795499.064698.2143nomascus_leucogenysENSNLEP0000001203699.487698.6336
ENSG00000133706homo_sapiensENSP0000037795499.744999.4898pan_paniscusENSPPAP0000000955299.660299.4053
ENSG00000133706homo_sapiensENSP0000037795499.319798.3844pongo_abeliiENSPPYP0000004341297.495896.5776
ENSG00000133706homo_sapiensENSP0000037795499.744999.4048pan_troglodytesENSPTRP0000008214199.660299.3203
ENSG00000133706homo_sapiensENSP0000037795499.659999.4048gorilla_gorillaENSGGOP0000000403999.575299.3203
ENSG00000133706homo_sapiensENSP0000037795494.727987.7551ornithorhynchus_anatinusENSOANP0000000917394.727987.7551
ENSG00000133706homo_sapiensENSP0000037795495.748390.2211sarcophilus_harrisiiENSSHAP0000004417395.748390.2211
ENSG00000133706homo_sapiensENSP0000037795449.234746.0884notamacropus_eugeniiENSMEUP0000000215049.318646.167
ENSG00000133706homo_sapiensENSP0000037795478.741576.1905choloepus_hoffmanniENSCHOP0000000824678.875676.3203
ENSG00000133706homo_sapiensENSP0000037795493.282389.1156dasypus_novemcinctusENSDNOP0000001394296.397292.0914
ENSG00000133706homo_sapiensENSP0000037795470.918468.3673erinaceus_europaeusENSEEUP0000001359370.918468.3673
ENSG00000133706homo_sapiensENSP0000037795472.959270.7483echinops_telfairiENSETEP0000000258479.37176.9658
ENSG00000133706homo_sapiensENSP0000037795498.639596.8537callithrix_jacchusENSCJAP0000003971497.47995.7143
ENSG00000133706homo_sapiensENSP0000037795496.598695.7483cercocebus_atysENSCATP0000001957298.100297.2366
ENSG00000133706homo_sapiensENSP0000037795499.319798.5544macaca_fascicularisENSMFAP0000003870499.319798.5544
ENSG00000133706homo_sapiensENSP0000037795499.234798.5544macaca_mulattaENSMMUP0000003393099.234798.5544
ENSG00000133706homo_sapiensENSP0000037795497.023896.3435macaca_nemestrinaENSMNEP0000004267199.303798.6075
ENSG00000133706homo_sapiensENSP0000037795496.173594.0476papio_anubisENSPANP0000004888994.2592.1667
ENSG00000133706homo_sapiensENSP0000037795499.149798.4694mandrillus_leucophaeusENSMLEP0000002689099.23498.5532
ENSG00000133706homo_sapiensENSP0000037795489.540886.3095tursiops_truncatusENSTTRP0000001584589.540886.3095
ENSG00000133706homo_sapiensENSP0000037795497.363994.6429vulpes_vulpesENSVVUP0000002889297.363994.6429
ENSG00000133706homo_sapiensENSP0000037795496.173590.3912mus_spretusMGP_SPRETEiJ_P004854096.010290.2377
ENSG00000133706homo_sapiensENSP0000037795474.064672.1939equus_asinusENSEASP0000503021398.30795.8239
ENSG00000133706homo_sapiensENSP0000037795496.853792.432capra_hircusENSCHIP0000001372496.853792.432
ENSG00000133706homo_sapiensENSP0000037795496.598693.2823loxodonta_africanaENSLAFP0000001861796.352893.045
ENSG00000133706homo_sapiensENSP0000037795497.53494.898panthera_leoENSPLOP0000001526897.53494.898
ENSG00000133706homo_sapiensENSP0000037795497.44994.6429ailuropoda_melanoleucaENSAMEP0000002456694.554591.8317
ENSG00000133706homo_sapiensENSP0000037795496.683792.0068bos_indicus_hybridENSBIXP0000503631996.683792.0068
ENSG00000133706homo_sapiensENSP0000037795494.812991.4116oryctolagus_cuniculusENSOCUP0000002997193.855290.4882
ENSG00000133706homo_sapiensENSP0000037795497.61994.2177equus_caballusENSECAP0000009061596.308792.953
ENSG00000133706homo_sapiensENSP0000037795497.363994.8129canis_lupus_familiarisENSCAFP0084502969293.545891.0948
ENSG00000133706homo_sapiensENSP0000037795497.53494.898panthera_pardusENSPPRP0000000231597.53494.898
ENSG00000133706homo_sapiensENSP0000037795492.006889.1156marmota_marmota_marmotaENSMMMP0000002081597.653494.5848
ENSG00000133706homo_sapiensENSP0000037795496.343592.517balaenoptera_musculusENSBMSP0001000519596.343592.517
ENSG00000133706homo_sapiensENSP0000037795497.193992.602cavia_porcellusENSCPOP0000001109297.359592.7598
ENSG00000133706homo_sapiensENSP0000037795497.363994.6429felis_catusENSFCAP0000000808197.363994.6429
ENSG00000133706homo_sapiensENSP0000037795492.176989.6258ursus_americanusENSUAMP0000002559897.394494.699
ENSG00000133706homo_sapiensENSP0000037795483.503478.4014monodelphis_domesticaENSMODP0000003148195.898490.0391
ENSG00000133706homo_sapiensENSP0000037795495.323190.6463bison_bison_bisonENSBBBP0000000110295.323190.6463
ENSG00000133706homo_sapiensENSP0000037795495.918492.1769monodon_monocerosENSMMNP000150047889692.2553
ENSG00000133706homo_sapiensENSP0000037795495.833391.2415sus_scrofaENSSSCP0000007283295.914991.3191
ENSG00000133706homo_sapiensENSP0000037795497.789195.068microcebus_murinusENSMICP0000001772297.789195.068
ENSG00000133706homo_sapiensENSP0000037795483.503479.8469microcebus_murinusENSMICP0000003859795.525391.3424
ENSG00000133706homo_sapiensENSP0000037795494.387890.1361octodon_degusENSODEP0000000653496.689992.3345
ENSG00000133706homo_sapiensENSP0000037795496.683791.9218jaculus_jaculusENSJJAP0000001218896.601591.8437
ENSG00000133706homo_sapiensENSP0000037795496.683792.1769ovis_aries_rambouilletENSOARP0002002619196.683792.1769
ENSG00000133706homo_sapiensENSP0000037795496.683792.0918ovis_aries_rambouilletENSOARP0002002852296.683792.0918
ENSG00000133706homo_sapiensENSP0000037795497.44994.5578ursus_maritimusENSUMAP0000001438497.44994.5578
ENSG00000133706homo_sapiensENSP0000037795472.193968.8775ochotona_princepsENSOPRP0000000286077.111773.5695
ENSG00000133706homo_sapiensENSP0000037795493.027288.3503delphinapterus_leucasENSDLEP0000000408391.242786.6555
ENSG00000133706homo_sapiensENSP0000037795496.173592.432physeter_catodonENSPCTP0000500313595.523791.8074
ENSG00000133706homo_sapiensENSP0000037795496.088490.2211mus_caroliMGP_CAROLIEiJ_P004661895.925390.0679
ENSG00000133706homo_sapiensENSP0000037795495.918489.966mus_musculusENSMUSP0000009519795.755589.8132
ENSG00000133706homo_sapiensENSP0000037795493.282388.5204dipodomys_ordiiENSDORP0000002342995.143190.2862
ENSG00000133706homo_sapiensENSP0000037795497.278994.6429mustela_putorius_furoENSMPUP0000000778697.278994.6429
ENSG00000133706homo_sapiensENSP0000037795490.221188.8605aotus_nancymaaeENSANAP0000000173198.881697.3905
ENSG00000133706homo_sapiensENSP0000037795495.323193.5374saimiri_boliviensis_boliviensisENSSBOP0000002035598.592896.7458
ENSG00000133706homo_sapiensENSP0000037795487.329983.5884vicugna_pacosENSVPAP0000000051487.404383.6596
ENSG00000133706homo_sapiensENSP0000037795498.894697.8742chlorocebus_sabaeusENSCSAP0000000847396.997595.9967
ENSG00000133706homo_sapiensENSP0000037795479.676976.7007tupaia_belangeriENSTBEP0000000330882.700879.6116
ENSG00000133706homo_sapiensENSP0000037795484.863978.7415mesocricetus_auratusENSMAUP0000000305891.896985.267
ENSG00000133706homo_sapiensENSP0000037795496.258592.517phocoena_sinusENSPSNP0000000166294.098190.4406
ENSG00000133706homo_sapiensENSP0000037795497.278993.5374camelus_dromedariusENSCDRP0000500938197.278993.5374
ENSG00000133706homo_sapiensENSP0000037795497.53494.0476carlito_syrichtaENSTSYP0000000116297.53494.0476
ENSG00000133706homo_sapiensENSP0000037795497.44994.7279panthera_tigris_altaicaENSPTIP0000001341797.44994.7279
ENSG00000133706homo_sapiensENSP0000037795495.833389.881rattus_norvegicusENSRNOP0000002528495.670689.7284
ENSG00000133706homo_sapiensENSP0000037795497.789194.898prolemur_simusENSPSMP0000001714797.789194.898
ENSG00000133706homo_sapiensENSP0000037795496.258590.1361microtus_ochrogasterENSMOCP0000000265496.095189.983
ENSG00000133706homo_sapiensENSP0000037795467.51764.2857sorex_araneusENSSARP0000001220767.747464.5051
ENSG00000133706homo_sapiensENSP0000037795489.625883.6735peromyscus_maniculatus_bairdiiENSPEMP0000000973793.688987.4667
ENSG00000133706homo_sapiensENSP0000037795496.768792.0918bos_mutusENSBMUP0000001071096.768792.0918
ENSG00000133706homo_sapiensENSP0000037795411.394610.7143mus_spicilegusENSMSIP0000001935993.055687.5
ENSG00000133706homo_sapiensENSP0000037795471.598664.6258mus_spicilegusENSMSIP0000000929288.352679.7482
ENSG00000133706homo_sapiensENSP0000037795485.629279.7619cricetulus_griseus_chok1gshdENSCGRP0000100377195.359888.8258
ENSG00000133706homo_sapiensENSP0000037795484.693980.1871pteropus_vampyrusENSPVAP0000001059588.141683.4513
ENSG00000133706homo_sapiensENSP0000037795496.428692.9422myotis_lucifugusENSMLUP0000000104196.510693.0213
ENSG00000133706homo_sapiensENSP0000037795495.918489.7959vombatus_ursinusENSVURP0001001143895.918489.7959
ENSG00000133706homo_sapiensENSP0000037795497.193993.6225rhinolophus_ferrumequinumENSRFEP0001001291697.276693.7021
ENSG00000133706homo_sapiensENSP0000037795497.278994.7279neovison_visonENSNVIP0000001378397.031494.4869
ENSG00000133706homo_sapiensENSP0000037795496.683792.0068bos_taurusENSBTAP0000000890296.683792.0068
ENSG00000133706homo_sapiensENSP0000037795497.363993.4524heterocephalus_glaber_femaleENSHGLP0000003634995.178791.3549
ENSG00000133706homo_sapiensENSP0000037795491.411690.8163rhinopithecus_bietiENSRBIP0000003949498.173597.5342
ENSG00000133706homo_sapiensENSP0000037795496.258593.4524canis_lupus_dingoENSCAFP0002003231494.648891.8896
ENSG00000133706homo_sapiensENSP0000037795497.704194.2177sciurus_vulgarisENSSVLP0000501722997.704194.2177
ENSG00000133706homo_sapiensENSP0000037795495.493288.7755phascolarctos_cinereusENSPCIP0000004190295.655988.9267
ENSG00000133706homo_sapiensENSP0000037795472.704169.2177procavia_capensisENSPCAP0000000539583.988279.9607
ENSG00000133706homo_sapiensENSP0000037795496.343592.1769nannospalax_galiliENSNGAP0000000872996.425592.2553
ENSG00000133706homo_sapiensENSP0000037795496.768792.0918bos_grunniensENSBGRP0000002091596.768792.0918
ENSG00000133706homo_sapiensENSP0000037795497.53493.0272chinchilla_lanigeraENSCLAP0000001626297.53493.0272
ENSG00000133706homo_sapiensENSP0000037795496.683792.0918cervus_hanglu_yarkandensisENSCHYP0000000309496.683792.0918
ENSG00000133706homo_sapiensENSP0000037795496.173591.0714catagonus_wagneriENSCWAP0000001658396.173591.0714
ENSG00000133706homo_sapiensENSP0000037795497.53494.3027ictidomys_tridecemlineatusENSSTOP0000000211797.53494.3027
ENSG00000133706homo_sapiensENSP0000037795491.836787.5otolemur_garnettiiENSOGAP0000000785194.488290.0262
ENSG00000133706homo_sapiensENSP0000037795498.554496.9388cebus_imitatorENSCCAP0000000642098.470796.8564
ENSG00000133706homo_sapiensENSP0000037795494.047690.9014urocitellus_parryiiENSUPAP0001001571597.359294.1021
ENSG00000133706homo_sapiensENSP0000037795496.683792.0918moschus_moschiferusENSMMSP0000000409296.683792.0918
ENSG00000133706homo_sapiensENSP0000037795412.58512.2449rhinopithecus_roxellanaENSRROP0000003646094.267591.7197
ENSG00000133706homo_sapiensENSP0000037795436.904836.5646rhinopithecus_roxellanaENSRROP0000000480399.086898.1735
ENSG00000133706homo_sapiensENSP0000037795496.003490.051mus_pahariMGP_PahariEiJ_P003920695.840489.8981
ENSG00000133706homo_sapiensENSP0000037795496.003493.3673propithecus_coquereliENSPCOP0000001520397.664494.9827
ENSG00000133706homo_sapiensENSP0000037795471.003456.2925caenorhabditis_elegansR74.1.170.404755.8179
ENSG00000133706homo_sapiensENSP0000037795474.149758.7585drosophila_melanogasterFBpp031170473.773358.4602
ENSG00000133706homo_sapiensENSP0000037795479.421864.3708ciona_intestinalisENSCINP0000001740579.152564.1525
ENSG00000133706homo_sapiensENSP0000037795420.663317.0068petromyzon_marinusENSPMAP0000000001986.170270.922
ENSG00000133706homo_sapiensENSP0000037795472.023856.2075eptatretus_burgeriENSEBUP0000002432176.72159.8732
ENSG00000133706homo_sapiensENSP0000037795487.925277.551callorhinchus_miliiENSCMIP0000000236085.809175.6846
ENSG00000133706homo_sapiensENSP0000037795490.731381.3775latimeria_chalumnaeENSLACP0000001057890.577281.2394
ENSG00000133706homo_sapiensENSP0000037795490.221179.2517lepisosteus_oculatusENSLOCP0000001280790.761379.7263
ENSG00000133706homo_sapiensENSP0000037795489.115678.2313clupea_harengusENSCHAP0000000981489.039978.1648
ENSG00000133706homo_sapiensENSP0000037795461.309553.9966danio_rerioENSDARP0000000335990.237879.4743
ENSG00000133706homo_sapiensENSP0000037795427.295924.0646danio_rerioENSDARP0000010673889.91679.2717
ENSG00000133706homo_sapiensENSP0000037795490.646379.0816carassius_auratusENSCARP0000007550490.492478.9474
ENSG00000133706homo_sapiensENSP0000037795490.391278.8265carassius_auratusENSCARP0000005037090.314478.7596
ENSG00000133706homo_sapiensENSP0000037795490.901479.932astyanax_mexicanusENSAMXP0000002059490.74779.7963
ENSG00000133706homo_sapiensENSP0000037795490.136179.5068ictalurus_punctatusENSIPUP0000001588190.136179.5068
ENSG00000133706homo_sapiensENSP0000037795488.860576.4456esox_luciusENSELUP0000005374888.559376.1864
ENSG00000133706homo_sapiensENSP0000037795487.58575electrophorus_electricusENSEEEP0000001379984.288172.1768
ENSG00000133706homo_sapiensENSP0000037795489.115677.2109oncorhynchus_kisutchENSOKIP0000511569889.039977.1453
ENSG00000133706homo_sapiensENSP0000037795415.646311.4796oncorhynchus_mykissENSOMYP0000006782768.656750.3731
ENSG00000133706homo_sapiensENSP0000037795489.200777.381oncorhynchus_mykissENSOMYP0000003352388.523276.7933
ENSG00000133706homo_sapiensENSP0000037795489.030677.2109salmo_salarENSSSAP0000010403589.030677.2109
ENSG00000133706homo_sapiensENSP0000037795488.860577.2109salmo_truttaENSSTUP0000003792784.752673.6415
ENSG00000133706homo_sapiensENSP0000037795414.625910.2891salmo_truttaENSSTUP0000001152157.718140.604
ENSG00000133706homo_sapiensENSP0000037795488.690576.1905gadus_morhuaENSGMOP0000004721387.942775.5481
ENSG00000133706homo_sapiensENSP0000037795481.802770.5782fundulus_heteroclitusENSFHEP0000000893890.074977.7154
ENSG00000133706homo_sapiensENSP0000037795490.306178.6565poecilia_reticulataENSPREP0000000842889.695978.125
ENSG00000133706homo_sapiensENSP0000037795490.476278.5714xiphophorus_maculatusENSXMAP0000000149189.864978.0405
ENSG00000133706homo_sapiensENSP0000037795490.561277.7211oryzias_latipesENSORLP0000003188989.949377.1959
ENSG00000133706homo_sapiensENSP0000037795488.945676.7007cyclopterus_lumpusENSCLMP0000502380387.166775.1667
ENSG00000133706homo_sapiensENSP0000037795490.901479.1667oreochromis_niloticusENSONIP0000005701490.287278.6318
ENSG00000133706homo_sapiensENSP0000037795488.690577.1258haplochromis_burtoniENSHBUP0000002260889.913878.1897
ENSG00000133706homo_sapiensENSP0000037795490.731378.8265astatotilapia_callipteraENSACLP0000001610790.118278.2939
ENSG00000133706homo_sapiensENSP0000037795490.136178.1463sparus_aurataENSSAUP0001001850489.376177.4874
ENSG00000133706homo_sapiensENSP0000037795490.136178.8265lates_calcariferENSLCAP0001004279988.777277.6382
ENSG00000133706homo_sapiensENSP0000037795492.857183.2483xenopus_tropicalisENSXETP0000000495592.778383.1776
ENSG00000133706homo_sapiensENSP0000037795493.537486.3095chrysemys_picta_belliiENSCPBP0000001099293.537486.3095
ENSG00000133706homo_sapiensENSP0000037795492.857186.0544sphenodon_punctatusENSSPUP0000001787192.699585.9083
ENSG00000133706homo_sapiensENSP0000037795492.261985.2891crocodylus_porosusENSCPRP0000501148292.576885.5802
ENSG00000133706homo_sapiensENSP0000037795426.955823.5544laticauda_laticaudataENSLLTP0000001639684.308573.6702
ENSG00000133706homo_sapiensENSP0000037795491.411682.9932notechis_scutatusENSNSUP0000001391391.489483.0638
ENSG00000133706homo_sapiensENSP0000037795491.751783.2483pseudonaja_textilisENSPTXP0000000144891.829883.3191
ENSG00000133706homo_sapiensENSP0000037795486.649779.5068anas_platyrhynchos_platyrhynchosENSAPLP0000002688490.8283.3333
ENSG00000133706homo_sapiensENSP0000037795493.452486.9048gallus_gallusENSGALP0001002325190.229983.908
ENSG00000133706homo_sapiensENSP0000037795493.282386.5646meleagris_gallopavoENSMGAP0000000976391.264684.6922
ENSG00000133706homo_sapiensENSP0000037795494.217786.4796serinus_canariaENSSCAP0000000226394.137686.4061
ENSG00000133706homo_sapiensENSP0000037795494.047686.5646parus_majorENSPMJP0000000756693.649586.1981
ENSG00000133706homo_sapiensENSP0000037795491.156584.6088anolis_carolinensisENSACAP0000004089891.389684.8252
ENSG00000133706homo_sapiensENSP0000037795490.731379.0816neolamprologus_brichardiENSNBRP0000000746990.118278.5473
ENSG00000133706homo_sapiensENSP0000037795491.666783.5884naja_najaENSNNAP0000001927891.744783.6596
ENSG00000133706homo_sapiensENSP0000037795492.261984.5238podarcis_muralisENSPMRP0000001709992.340484.5957
ENSG00000133706homo_sapiensENSP0000037795489.795982.8231geospiza_fortisENSGFOP0000001831094.033886.732
ENSG00000133706homo_sapiensENSP0000037795493.707586.2245taeniopygia_guttataENSTGUP0000000012093.627986.1512
ENSG00000133706homo_sapiensENSP0000037795490.05178.9966erpetoichthys_calabaricusENSECRP0000001229789.974578.9295
ENSG00000133706homo_sapiensENSP0000037795489.96678.4014kryptolebias_marmoratusENSKMAP0000001326989.282777.8059
ENSG00000133706homo_sapiensENSP0000037795492.857184.949salvator_merianaeENSSMRP0000002321990.773183.0424
ENSG00000133706homo_sapiensENSP0000037795490.476277.7211oryzias_javanicusENSOJAP0000002675086.293674.1281
ENSG00000133706homo_sapiensENSP0000037795489.285777.8061amphilophus_citrinellusENSACIP0000001807088.907777.4767
ENSG00000133706homo_sapiensENSP0000037795490.391278.5714dicentrarchus_labraxENSDLAP0000501490282.211971.4617
ENSG00000133706homo_sapiensENSP0000037795490.816379.1667amphiprion_perculaENSAPEP0000002501690.202778.6318
ENSG00000133706homo_sapiensENSP0000037795483.248371.1735oryzias_sinensisENSOSIP0000003531387.802775.0673
ENSG00000133706homo_sapiensENSP0000037795493.197385.7993pelodiscus_sinensisENSPSIP0000001783993.755386.3131
ENSG00000133706homo_sapiensENSP0000037795493.622585.5442gopherus_evgoodeiENSGEVP0000501064693.542985.4715
ENSG00000133706homo_sapiensENSP0000037795491.411683.0782chelonoidis_abingdoniiENSCABP0000001855691.723583.3618
ENSG00000133706homo_sapiensENSP0000037795490.561278.9116seriola_dumeriliENSSDUP0000002939489.949378.3784
ENSG00000133706homo_sapiensENSP0000037795488.095276.9558cottoperca_gobioENSCGOP0000001865986.767275.7956
ENSG00000133706homo_sapiensENSP0000037795489.625882.9082struthio_camelus_australisENSSCUP0000000291593.939486.8984
ENSG00000133706homo_sapiensENSP0000037795494.132786.8197anser_brachyrhynchusENSABRP0000001918693.33986.0877
ENSG00000133706homo_sapiensENSP0000037795488.945676.3605gasterosteus_aculeatusENSGACP0000002739589.401776.7521
ENSG00000133706homo_sapiensENSP0000037795490.221177.8912cynoglossus_semilaevisENSCSEP0000002351188.638376.5246
ENSG00000133706homo_sapiensENSP0000037795490.986478.9966poecilia_formosaENSPFOP0000000293990.371678.4628
ENSG00000133706homo_sapiensENSP0000037795489.455878.3163myripristis_murdjanENSMMDP0000502278286.655775.8649
ENSG00000133706homo_sapiensENSP0000037795490.391278.4864sander_luciopercaENSSLUP0000005740889.780477.9561
ENSG00000133706homo_sapiensENSP0000037795494.132787.0748strigops_habroptilaENSSHBP0000501965694.052787.0008
ENSG00000133706homo_sapiensENSP0000037795490.731379.0816amphiprion_ocellarisENSAOCP0000001237690.118278.5473
ENSG00000133706homo_sapiensENSP0000037795493.707586.3946terrapene_carolina_triunguisENSTMTP0000002307793.627986.3212
ENSG00000133706homo_sapiensENSP0000037795489.200777.6361hucho_huchoENSHHUP0000006994488.973777.4385
ENSG00000133706homo_sapiensENSP0000037795490.646378.8265betta_splendensENSBSLP0000000550590.109978.3601
ENSG00000133706homo_sapiensENSP0000037795490.221179.0816pygocentrus_nattereriENSPNAP0000002028190.144479.0144
ENSG00000133706homo_sapiensENSP0000037795489.96678.4014anabas_testudineusENSATEP0000004202389.813278.2682
ENSG00000133706homo_sapiensENSP0000037795478.401463.6054ciona_savignyiENSCSAVP0000001540777.937463.2291
ENSG00000133706homo_sapiensENSP0000037795458.928642.0918saccharomyces_cerevisiaeYPL160W63.57845.4128
ENSG00000133706homo_sapiensENSP0000037795490.561278.9116seriola_lalandi_dorsalisENSSLDP0000000897989.949378.3784
ENSG00000133706homo_sapiensENSP0000037795490.561278.9116labrus_bergyltaENSLBEP0000003351588.162376.8212
ENSG00000133706homo_sapiensENSP0000037795490.646378.5714pundamilia_nyerereiENSPNYP0000002023190.033878.0405
ENSG00000133706homo_sapiensENSP0000037795490.476278.9116mastacembelus_armatusENSMAMP0000003177089.864978.3784
ENSG00000133706homo_sapiensENSP0000037795490.731378.9116stegastes_partitusENSSPAP0000001615890.118278.3784
ENSG00000133706homo_sapiensENSP0000037795489.115677.0408oncorhynchus_tshawytschaENSOTSP0000507549888.964376.91
ENSG00000133706homo_sapiensENSP0000037795489.115677.0408oncorhynchus_tshawytschaENSOTSP0000510388388.964376.91
ENSG00000133706homo_sapiensENSP0000037795491.071478.9116acanthochromis_polyacanthusENSAPOP0000000830590.303578.2462
ENSG00000133706homo_sapiensENSP0000037795494.132787.2449aquila_chrysaetos_chrysaetosENSACCP0002002080994.052787.1708
ENSG00000133706homo_sapiensENSP0000037795487.840176.6156nothobranchius_furzeriENSNFUP0001501285887.69176.4856
ENSG00000133706homo_sapiensENSP0000037795491.241579.2517cyprinodon_variegatusENSCVAP0000001221690.778378.8494
ENSG00000133706homo_sapiensENSP0000037795489.88177.8912denticeps_clupeoidesENSDCDP0000006111389.652277.693
ENSG00000133706homo_sapiensENSP0000037795489.455878.7415takifugu_rubripesENSTRUP0000006855686.942176.5289
ENSG00000133706homo_sapiensENSP0000037795493.537485.9694ficedula_albicollisENSFALP0000000334286.614279.6063
ENSG00000133706homo_sapiensENSP0000037795489.200777.381hippocampus_comesENSHCOP0000000245488.672976.9231
ENSG00000133706homo_sapiensENSP0000037795490.391278.8265cyprinus_carpio_carpioENSCCRP0000007752489.62978.1619
ENSG00000133706homo_sapiensENSP0000037795490.731378.9966cyprinus_carpio_carpioENSCCRP0000016488390.654278.9295
ENSG00000133706homo_sapiensENSP0000037795493.622587.1599coturnix_japonicaENSCJPP0000502689893.542987.0858
ENSG00000133706homo_sapiensENSP0000037795491.071479.1667poecilia_latipinnaENSPLAP0000001304790.456178.6318
ENSG00000133706homo_sapiensENSP0000037795430.782326.4456sinocyclocheilus_grahamiENSSGRP0000011073884.18672.3256
ENSG00000133706homo_sapiensENSP0000037795490.391278.7415sinocyclocheilus_grahamiENSSGRP0000008637490.314478.6746
ENSG00000133706homo_sapiensENSP0000037795490.646378.7415maylandia_zebraENSMZEP0000500352790.033878.2095
ENSG00000133706homo_sapiensENSP0000037795486.819775.2551tetraodon_nigroviridisENSTNIP0000002138086.967675.3833
ENSG00000133706homo_sapiensENSP0000037795488.605477.381paramormyrops_kingsleyaeENSPKIP0000002285184.784474.0439
ENSG00000133706homo_sapiensENSP0000037795490.05179.3367scleropages_formosusENSSFOP0001505628989.974579.2693
ENSG00000133706homo_sapiensENSP0000037795491.411681.8878leptobrachium_leishanenseENSLLEP0000004516091.489481.9574
ENSG00000133706homo_sapiensENSP0000037795490.306178.4014scophthalmus_maximusENSSMAP0000005220889.620377.8059
ENSG00000133706homo_sapiensENSP0000037795490.306178.1463oryzias_melastigmaENSOMEP0000002478889.695977.6182

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0002161enables aminoacyl-tRNA editing activity1IEAHomo_sapiens(9606)Function
GO:0004819enables glutamine-tRNA ligase activity1IDAHomo_sapiens(9606)Function
GO:0004823enables leucine-tRNA ligase activity2IBA,TASHomo_sapiens(9606)Function
GO:0005096enables GTPase activator activity1IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005764located_in lysosome1IMPHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006418involved_in tRNA aminoacylation for protein translation1TASHomo_sapiens(9606)Process
GO:0006425involved_in glutaminyl-tRNA aminoacylation1IDAHomo_sapiens(9606)Process
GO:0006429involved_in leucyl-tRNA aminoacylation1IBAHomo_sapiens(9606)Process
GO:0008361involved_in regulation of cell size1IMPHomo_sapiens(9606)Process
GO:0012505located_in endomembrane system1IDAHomo_sapiens(9606)Component
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0017101part_of aminoacyl-tRNA synthetase multienzyme complex1IDAHomo_sapiens(9606)Component
GO:0032008involved_in positive regulation of TOR signaling1IMPHomo_sapiens(9606)Process
GO:0034198involved_in cellular response to amino acid starvation1IMPHomo_sapiens(9606)Process
GO:0043547involved_in positive regulation of GTPase activity1IMPHomo_sapiens(9606)Process
GO:0071230involved_in cellular response to amino acid stimulus1IMPHomo_sapiens(9606)Process
GO:0071233involved_in cellular response to leucine1IMPHomo_sapiens(9606)Process
GO:0106074involved_in aminoacyl-tRNA metabolism involved in translational fidelity1IEAHomo_sapiens(9606)Process
GO:1904263involved_in positive regulation of TORC1 signaling1IMPHomo_sapiens(9606)Process
GO:1990253involved_in cellular response to leucine starvation1IMPHomo_sapiens(9606)Process

Expression