RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000133703	Gene ID	3845	Accession	6407
Symbol	KRAS	Alias	NS;NS3;OES;CFC2;RALD;K-Ras;KRAS1;KRAS2;RASK2;KI-RAS;C-K-RAS;K-RAS2A;K-RAS2B;K-RAS4A;K-RAS4B;K-Ras2;'C-K-RAS;c-Ki-ras;c-Ki-ras2	Full Name	KRAS proto-oncogene, GTPase
Status	Confidence	Length	45691 bases	Strand	Minus strand
Position	12 : 25205246 - 25250936	RNA binding domain	GTP_EFTU , MMR_HSR1
Summary	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]