RBP Type
Canonical_RBPs
Diseases
CHIKV SARS-COV-OC43 Flaviviruses HIV RV Dengue
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000132383 Gene ID
6117 Accession
10289
Symbol
RPA1
Alias
HSSB;RF-A;RP-A;REPA1;RPA70;MST075;PFBMFT6
Full Name
replication protein A1
Status
Confidence
Length
70381 bases
Strand
Plus strand
Position
17 : 1829702 - 1900082
RNA binding domain
tRNA_anti-codon
Summary
This gene encodes the largest subunit of the heterotrimeric Replication Protein A (RPA) complex, which binds to single-stranded DNA (ssDNA), forming a nucleoprotein complex that plays an important role in DNA metabolism, being involved in DNA replication, repair, recombination, telomere maintenance, and co-ordinating the cellular response to DNA damage through activation of the ataxia telangiectasia and Rad3-related protein (ATR) kinase. The nucleoprotein complex protects the single-stranded DNA from nucleases, prevents formation of secondary structures that would interfere with repair, and co-ordinates the recruitment and departure of different genome maintenance factors. This subunit contains four oligonucleotide/oligosaccharide-binding (OB) domains, though the majority of ssDNA binding occurs in two of these domains. The heterotrimeric complex has two different modes of ssDNA binding, a low-affinity and high-affinity mode, determined by which ssDNA binding domains are utilized. The different binding modes differ in the length of DNA bound and in the proteins with which it interacts, thereby playing a role in regulating different genomic maintenance pathways. [provided by RefSeq, Sep 2017]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000254719
tRNA_anti-codon
PF01336 1.7e-11
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
RPA1-203
ENST00000571058
577
124aa
ENSP00000461733
RPA1-202
ENST00000570451
630
153aa
ENSP00000459788
RPA1-201
ENST00000254719
4847
616aa
ENSP00000254719
RPA1-204
ENST00000571725
413
No protein
-
RPA1-205
ENST00000573924
574
No protein
-
RPA1-207
ENST00000574049
3849
313aa
ENSP00000461466
RPA1-206
ENST00000573994
844
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
15981 Stroke 4.0969650E-004 19369658 27718 Coronary Disease 9.4970000E-005 - 31856 Forced Expiratory Volume 2.7380000E-005 - 31878 Forced Expiratory Volume 2.7380000E-005 - 37086 Platelet Function Tests 1.3159700E-005 - 101854 Tomography Scanners, X-Ray Computed 2E-6 26030696
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000132383
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000132383 homo_sapiens ENSP00000254719 99.1883 98.3766 nomascus_leucogenys ENSNLEP00000020837 99.1883 98.3766 ENSG00000132383 homo_sapiens ENSP00000254719 99.3506 99.026 pan_paniscus ENSPPAP00000033667 99.3506 99.026 ENSG00000132383 homo_sapiens ENSP00000254719 99.3506 98.8636 pongo_abelii ENSPPYP00000036052 99.3506 98.8636 ENSG00000132383 homo_sapiens ENSP00000254719 99.6753 99.513 pan_troglodytes ENSPTRP00000014573 99.6753 99.513 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 94.8052 gorilla_gorilla ENSGGOP00000013840 99.8291 99.8291 ENSG00000132383 homo_sapiens ENSP00000254719 90.0974 81.0065 ornithorhynchus_anatinus ENSOANP00000017238 91.2829 82.0724 ENSG00000132383 homo_sapiens ENSP00000254719 92.6948 83.2792 sarcophilus_harrisii ENSSHAP00000009204 90.3481 81.1709 ENSG00000132383 homo_sapiens ENSP00000254719 81.1688 70.7792 notamacropus_eugenii ENSMEUP00000006133 82.5082 71.9472 ENSG00000132383 homo_sapiens ENSP00000254719 88.1494 83.4416 choloepus_hoffmanni ENSCHOP00000011994 92.3469 87.415 ENSG00000132383 homo_sapiens ENSP00000254719 69.1558 65.9091 choloepus_hoffmanni ENSCHOP00000008359 97.0387 92.4829 ENSG00000132383 homo_sapiens ENSP00000254719 93.6688 88.474 dasypus_novemcinctus ENSDNOP00000013346 93.6688 88.474 ENSG00000132383 homo_sapiens ENSP00000254719 68.0195 63.3117 erinaceus_europaeus ENSEEUP00000001992 68.0195 63.3117 ENSG00000132383 homo_sapiens ENSP00000254719 75.487 68.6688 echinops_telfairi ENSETEP00000014300 76.1047 69.2308 ENSG00000132383 homo_sapiens ENSP00000254719 96.4286 92.8571 callithrix_jacchus ENSCJAP00000003336 94.586 91.0828 ENSG00000132383 homo_sapiens ENSP00000254719 41.8831 41.5584 cercocebus_atys ENSCATP00000036401 98.4733 97.7099 ENSG00000132383 homo_sapiens ENSP00000254719 98.0519 96.4286 macaca_fascicularis ENSMFAP00000007027 98.0519 96.4286 ENSG00000132383 homo_sapiens ENSP00000254719 98.3766 96.7533 macaca_mulatta ENSMMUP00000042285 98.3766 96.7533 ENSG00000132383 homo_sapiens ENSP00000254719 67.6948 66.3961 macaca_mulatta ENSMMUP00000069269 95.4233 93.5927 ENSG00000132383 homo_sapiens ENSP00000254719 83.6039 81.3312 macaca_nemestrina ENSMNEP00000010901 94.1499 91.5905 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 93.9935 macaca_nemestrina ENSMNEP00000015014 98.3222 97.1477 ENSG00000132383 homo_sapiens ENSP00000254719 98.3766 96.9156 papio_anubis ENSPANP00000019488 98.3766 96.9156 ENSG00000132383 homo_sapiens ENSP00000254719 76.1364 74.1883 papio_anubis ENSPANP00000055276 96.3039 93.8398 ENSG00000132383 homo_sapiens ENSP00000254719 42.2078 41.5584 mandrillus_leucophaeus ENSMLEP00000006951 97.0149 95.5224 ENSG00000132383 homo_sapiens ENSP00000254719 91.7208 89.1234 mandrillus_leucophaeus ENSMLEP00000029121 94.958 92.2689 ENSG00000132383 homo_sapiens ENSP00000254719 93.6688 88.474 tursiops_truncatus ENSTTRP00000001099 93.517 88.3306 ENSG00000132383 homo_sapiens ENSP00000254719 94.6429 89.1234 vulpes_vulpes ENSVVUP00000029706 94.6429 89.1234 ENSG00000132383 homo_sapiens ENSP00000254719 92.3701 85.7143 mus_spretus MGP_SPRETEiJ_P0029622 88.2171 81.8605 ENSG00000132383 homo_sapiens ENSP00000254719 96.5909 91.3961 equus_asinus ENSEASP00005013473 96.5909 91.3961 ENSG00000132383 homo_sapiens ENSP00000254719 93.9935 88.7987 capra_hircus ENSCHIP00000032279 93.8412 88.6548 ENSG00000132383 homo_sapiens ENSP00000254719 95.7792 89.9351 loxodonta_africana ENSLAFP00000012864 91.7574 86.1586 ENSG00000132383 homo_sapiens ENSP00000254719 94.3182 87.6623 panthera_leo ENSPLOP00000016981 94.0129 87.3786 ENSG00000132383 homo_sapiens ENSP00000254719 95.4545 89.6104 ailuropoda_melanoleuca ENSAMEP00000043792 88.2883 82.8829 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 90.5844 bos_indicus_hybrid ENSBIXP00005032333 95.1299 90.5844 ENSG00000132383 homo_sapiens ENSP00000254719 94.4805 88.7987 oryctolagus_cuniculus ENSOCUP00000042935 92.2346 86.6878 ENSG00000132383 homo_sapiens ENSP00000254719 96.4286 91.0714 equus_caballus ENSECAP00000021472 95.1923 89.9038 ENSG00000132383 homo_sapiens ENSP00000254719 93.5065 87.6623 canis_lupus_familiaris ENSCAFP00845019430 92.3077 86.5385 ENSG00000132383 homo_sapiens ENSP00000254719 94.3182 87.8247 panthera_pardus ENSPPRP00000020864 94.0129 87.5405 ENSG00000132383 homo_sapiens ENSP00000254719 92.3701 87.987 marmota_marmota_marmota ENSMMMP00000027604 95.1505 90.6355 ENSG00000132383 homo_sapiens ENSP00000254719 94.9675 89.7727 balaenoptera_musculus ENSBMSP00010026918 94.8136 89.6272 ENSG00000132383 homo_sapiens ENSP00000254719 94.3182 88.961 cavia_porcellus ENSCPOP00000000030 94.3182 88.961 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 88.1494 felis_catus ENSFCAP00000005860 94.4984 87.8641 ENSG00000132383 homo_sapiens ENSP00000254719 87.8247 80.5195 ursus_americanus ENSUAMP00000021083 78.9781 72.4088 ENSG00000132383 homo_sapiens ENSP00000254719 92.3701 83.2792 monodelphis_domestica ENSMODP00000013221 92.2204 83.1442 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 90.5844 bison_bison_bison ENSBBBP00000014735 95.1299 90.5844 ENSG00000132383 homo_sapiens ENSP00000254719 94.6429 89.9351 monodon_monoceros ENSMMNP00015027856 94.4895 89.7893 ENSG00000132383 homo_sapiens ENSP00000254719 92.8571 86.8506 sus_scrofa ENSSSCP00000063468 93.9245 87.8489 ENSG00000132383 homo_sapiens ENSP00000254719 96.1039 91.2338 microcebus_murinus ENSMICP00000032654 96.1039 91.2338 ENSG00000132383 homo_sapiens ENSP00000254719 91.0714 85.8766 octodon_degus ENSODEP00000012179 90.6301 85.4604 ENSG00000132383 homo_sapiens ENSP00000254719 91.8831 86.8506 jaculus_jaculus ENSJJAP00000001025 94.4908 89.3155 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 90.4221 ovis_aries_rambouillet ENSOARP00020028915 78.7634 74.8656 ENSG00000132383 homo_sapiens ENSP00000254719 95.6169 89.6104 ursus_maritimus ENSUMAP00000012546 95.6169 89.6104 ENSG00000132383 homo_sapiens ENSP00000254719 73.7013 68.3442 ochotona_princeps ENSOPRP00000000494 75.1656 69.702 ENSG00000132383 homo_sapiens ENSP00000254719 91.3961 86.3636 delphinapterus_leucas ENSDLEP00000016336 91.1003 86.0841 ENSG00000132383 homo_sapiens ENSP00000254719 95.2922 89.9351 physeter_catodon ENSPCTP00005008520 95.1378 89.7893 ENSG00000132383 homo_sapiens ENSP00000254719 92.8571 86.8506 mus_caroli MGP_CAROLIEiJ_P0028229 92.7066 86.7099 ENSG00000132383 homo_sapiens ENSP00000254719 92.2078 85.5519 mus_musculus ENSMUSP00000000767 88.1988 81.8323 ENSG00000132383 homo_sapiens ENSP00000254719 94.9675 90.2597 dipodomys_ordii ENSDORP00000025247 94.9675 90.2597 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 88.3117 mustela_putorius_furo ENSMPUP00000013022 94.8052 88.3117 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 92.5325 aotus_nancymaae ENSANAP00000010977 96.8491 94.5274 ENSG00000132383 homo_sapiens ENSP00000254719 91.3961 89.2857 saimiri_boliviensis_boliviensis ENSSBOP00000027651 97.4048 95.1557 ENSG00000132383 homo_sapiens ENSP00000254719 92.8571 88.3117 vicugna_pacos ENSVPAP00000008786 93.3116 88.7439 ENSG00000132383 homo_sapiens ENSP00000254719 88.7987 86.6883 chlorocebus_sabaeus ENSCSAP00000009979 98.2047 95.8707 ENSG00000132383 homo_sapiens ENSP00000254719 77.5974 73.8636 tupaia_belangeri ENSTBEP00000002354 80.2013 76.3423 ENSG00000132383 homo_sapiens ENSP00000254719 92.5325 87.1753 mesocricetus_auratus ENSMAUP00000009236 94.8419 89.3511 ENSG00000132383 homo_sapiens ENSP00000254719 94.9675 89.9351 camelus_dromedarius ENSCDRP00005014170 94.9675 89.9351 ENSG00000132383 homo_sapiens ENSP00000254719 39.1234 36.6883 carlito_syrichta ENSTSYP00000026533 94.1406 88.2812 ENSG00000132383 homo_sapiens ENSP00000254719 96.4286 92.5325 carlito_syrichta ENSTSYP00000003191 96.2723 92.3825 ENSG00000132383 homo_sapiens ENSP00000254719 94.3182 87.6623 panthera_tigris_altaica ENSPTIP00000005778 94.0129 87.3786 ENSG00000132383 homo_sapiens ENSP00000254719 91.5584 85.8766 rattus_norvegicus ENSRNOP00000079958 82.9412 77.7941 ENSG00000132383 homo_sapiens ENSP00000254719 95.7792 90.2597 prolemur_simus ENSPSMP00000029567 95.7792 90.2597 ENSG00000132383 homo_sapiens ENSP00000254719 92.3701 85.3896 microtus_ochrogaster ENSMOCP00000013137 89.4654 82.7044 ENSG00000132383 homo_sapiens ENSP00000254719 73.2143 68.3442 sorex_araneus ENSSARP00000006810 74.6689 69.702 ENSG00000132383 homo_sapiens ENSP00000254719 94.6429 88.474 peromyscus_maniculatus_bairdii ENSPEMP00000024265 94.9511 88.7622 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 90.5844 bos_mutus ENSBMUP00000013619 95.1299 90.5844 ENSG00000132383 homo_sapiens ENSP00000254719 92.3701 85.7143 mus_spicilegus ENSMSIP00000028470 88.6293 82.243 ENSG00000132383 homo_sapiens ENSP00000254719 94.1558 88.3117 cricetulus_griseus_chok1gshd ENSCGRP00001006120 93.6995 87.8837 ENSG00000132383 homo_sapiens ENSP00000254719 95.7792 89.4481 pteropus_vampyrus ENSPVAP00000002031 95.7792 89.4481 ENSG00000132383 homo_sapiens ENSP00000254719 93.6688 87.1753 myotis_lucifugus ENSMLUP00000005592 92.9147 86.4734 ENSG00000132383 homo_sapiens ENSP00000254719 91.5584 81.0065 vombatus_ursinus ENSVURP00010010339 91.2621 80.7443 ENSG00000132383 homo_sapiens ENSP00000254719 94.4805 87.987 rhinolophus_ferrumequinum ENSRFEP00010011175 94.4805 87.987 ENSG00000132383 homo_sapiens ENSP00000254719 94.9675 88.6364 neovison_vison ENSNVIP00000014150 94.9675 88.6364 ENSG00000132383 homo_sapiens ENSP00000254719 94.9675 90.4221 bos_taurus ENSBTAP00000012812 94.9675 90.4221 ENSG00000132383 homo_sapiens ENSP00000254719 95.6169 90.4221 heterocephalus_glaber_female ENSHGLP00000051920 95.6169 90.4221 ENSG00000132383 homo_sapiens ENSP00000254719 14.6104 13.6364 heterocephalus_glaber_female ENSHGLP00000049952 84.9057 79.2453 ENSG00000132383 homo_sapiens ENSP00000254719 41.3961 39.2857 heterocephalus_glaber_female ENSHGLP00000048140 95.1493 90.2985 ENSG00000132383 homo_sapiens ENSP00000254719 97.8896 95.4545 rhinopithecus_bieti ENSRBIP00000025409 97.8896 95.4545 ENSG00000132383 homo_sapiens ENSP00000254719 94.6429 88.961 canis_lupus_dingo ENSCAFP00020012233 94.6429 88.961 ENSG00000132383 homo_sapiens ENSP00000254719 95.2922 90.7467 sciurus_vulgaris ENSSVLP00005029164 95.2922 90.7467 ENSG00000132383 homo_sapiens ENSP00000254719 91.7208 82.3052 phascolarctos_cinereus ENSPCIP00000025334 91.2763 81.9063 ENSG00000132383 homo_sapiens ENSP00000254719 56.8182 53.0844 procavia_capensis ENSPCAP00000011986 56.8182 53.0844 ENSG00000132383 homo_sapiens ENSP00000254719 92.6948 85.5519 nannospalax_galili ENSNGAP00000003767 91.0686 84.051 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 90.5844 bos_grunniens ENSBGRP00000039805 95.1299 90.5844 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 89.9351 chinchilla_lanigera ENSCLAP00000007374 94.9594 90.0813 ENSG00000132383 homo_sapiens ENSP00000254719 90.2597 85.0649 chinchilla_lanigera ENSCLAP00000021957 93.1323 87.7722 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 89.6104 cervus_hanglu_yarkandensis ENSCHYP00000019264 94.8052 89.6104 ENSG00000132383 homo_sapiens ENSP00000254719 95.1299 89.4481 catagonus_wagneri ENSCWAP00000001626 95.1299 89.4481 ENSG00000132383 homo_sapiens ENSP00000254719 87.3377 81.9805 ictidomys_tridecemlineatus ENSSTOP00000016703 90.8784 85.3041 ENSG00000132383 homo_sapiens ENSP00000254719 73.539 68.6688 otolemur_garnettii ENSOGAP00000017689 95.7717 89.4292 ENSG00000132383 homo_sapiens ENSP00000254719 93.9935 88.474 otolemur_garnettii ENSOGAP00000017150 90.1869 84.891 ENSG00000132383 homo_sapiens ENSP00000254719 87.6623 85.5519 cebus_imitator ENSCCAP00000001716 96.9479 94.614 ENSG00000132383 homo_sapiens ENSP00000254719 88.1494 83.9286 urocitellus_parryii ENSUPAP00010022633 95.0963 90.5429 ENSG00000132383 homo_sapiens ENSP00000254719 94.8052 89.9351 moschus_moschiferus ENSMMSP00000008067 87.8195 83.3083 ENSG00000132383 homo_sapiens ENSP00000254719 92.0455 89.7727 rhinopithecus_roxellana ENSRROP00000039968 97.7586 95.3448 ENSG00000132383 homo_sapiens ENSP00000254719 93.5065 88.1494 mus_pahari MGP_PahariEiJ_P0034970 92.9032 87.5806 ENSG00000132383 homo_sapiens ENSP00000254719 96.4286 91.5584 propithecus_coquereli ENSPCOP00000000581 96.4286 91.5584 ENSG00000132383 homo_sapiens ENSP00000254719 48.2143 27.9221 caenorhabditis_elegans F18A1.5.1 45.3435 26.2595 ENSG00000132383 homo_sapiens ENSP00000254719 24.026 13.3117 caenorhabditis_elegans R03H10.7.1 41.2256 22.8412 ENSG00000132383 homo_sapiens ENSP00000254719 21.2662 10.8766 caenorhabditis_elegans R03H10.6.1 40.4321 20.679 ENSG00000132383 homo_sapiens ENSP00000254719 61.039 43.0195 drosophila_melanogaster FBpp0081356 62.3549 43.9469 ENSG00000132383 homo_sapiens ENSP00000254719 62.1753 41.7208 ciona_intestinalis ENSCINP00000034174 63.0972 42.3394 ENSG00000132383 homo_sapiens ENSP00000254719 25 17.8571 petromyzon_marinus ENSPMAP00000008944 69.0583 49.3274 ENSG00000132383 homo_sapiens ENSP00000254719 24.1883 18.6688 petromyzon_marinus ENSPMAP00000008662 73.399 56.6502 ENSG00000132383 homo_sapiens ENSP00000254719 64.7727 47.7273 eptatretus_burgeri ENSEBUP00000003989 68.5567 50.5155 ENSG00000132383 homo_sapiens ENSP00000254719 54.7078 38.3117 eptatretus_burgeri ENSEBUP00000006068 62.7561 43.9479 ENSG00000132383 homo_sapiens ENSP00000254719 81.4935 67.3701 callorhinchus_milii ENSCMIP00000046808 83.5275 69.0516 ENSG00000132383 homo_sapiens ENSP00000254719 65.4221 53.7338 latimeria_chalumnae ENSLACP00000008142 81.4141 66.8687 ENSG00000132383 homo_sapiens ENSP00000254719 81.0065 66.5584 lepisosteus_oculatus ENSLOCP00000007742 82.2076 67.5453 ENSG00000132383 homo_sapiens ENSP00000254719 76.9481 61.2013 clupea_harengus ENSCHAP00000013547 78.089 62.1087 ENSG00000132383 homo_sapiens ENSP00000254719 80.1948 62.8247 danio_rerio ENSDARP00000029067 82.1963 64.3927 ENSG00000132383 homo_sapiens ENSP00000254719 75.6494 59.0909 carassius_auratus ENSCARP00000098706 80.0687 62.543 ENSG00000132383 homo_sapiens ENSP00000254719 78.5714 60.7143 carassius_auratus ENSCARP00000047082 78.3172 60.5178 ENSG00000132383 homo_sapiens ENSP00000254719 79.2208 62.8247 carassius_auratus ENSCARP00000128372 80.1314 63.5468 ENSG00000132383 homo_sapiens ENSP00000254719 78.7338 61.3636 astyanax_mexicanus ENSAMXP00000028886 80.4312 62.6866 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.013 ictalurus_punctatus ENSIPUP00000006391 81.0231 63.0363 ENSG00000132383 homo_sapiens ENSP00000254719 67.6948 50.974 esox_lucius ENSELUP00000056509 49.9401 37.6048 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.013 esox_lucius ENSELUP00000022084 80.8896 62.9325 ENSG00000132383 homo_sapiens ENSP00000254719 77.4351 60.5519 electrophorus_electricus ENSEEEP00000001444 76.4423 59.7756 ENSG00000132383 homo_sapiens ENSP00000254719 73.3766 57.1429 oncorhynchus_kisutch ENSOKIP00005104255 72.4359 56.4103 ENSG00000132383 homo_sapiens ENSP00000254719 56.0065 42.6948 oncorhynchus_kisutch ENSOKIP00005096416 70.6967 53.8934 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 61.6883 oncorhynchus_kisutch ENSOKIP00005055403 79.0323 61.2903 ENSG00000132383 homo_sapiens ENSP00000254719 70.4545 54.3831 oncorhynchus_mykiss ENSOMYP00000140783 72.3333 55.8333 ENSG00000132383 homo_sapiens ENSP00000254719 74.026 57.3052 oncorhynchus_mykiss ENSOMYP00000110915 74.8768 57.9639 ENSG00000132383 homo_sapiens ENSP00000254719 70.4545 52.4351 oncorhynchus_mykiss ENSOMYP00000141324 64.8729 48.281 ENSG00000132383 homo_sapiens ENSP00000254719 62.3377 48.539 salmo_salar ENSSSAP00000169275 69.4394 54.0687 ENSG00000132383 homo_sapiens ENSP00000254719 79.8701 62.5 salmo_salar ENSSSAP00000061104 80.7882 63.2184 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 61.6883 salmo_salar ENSSSAP00000050494 79.288 61.4887 ENSG00000132383 homo_sapiens ENSP00000254719 79.2208 61.2013 salmo_trutta ENSSTUP00000111028 76.7296 59.2767 ENSG00000132383 homo_sapiens ENSP00000254719 59.0909 46.1039 salmo_trutta ENSSTUP00000079836 70.4062 54.9323 ENSG00000132383 homo_sapiens ENSP00000254719 78.0844 60.5519 salmo_trutta ENSSTUP00000090194 78.8525 61.1475 ENSG00000132383 homo_sapiens ENSP00000254719 73.7013 57.9545 gadus_morhua ENSGMOP00000055550 75.9197 59.699 ENSG00000132383 homo_sapiens ENSP00000254719 31.9805 25.3247 fundulus_heteroclitus ENSFHEP00000011881 77.8656 61.6601 ENSG00000132383 homo_sapiens ENSP00000254719 77.1104 61.2013 fundulus_heteroclitus ENSFHEP00000022905 78.6424 62.4172 ENSG00000132383 homo_sapiens ENSP00000254719 66.7208 52.5974 poecilia_reticulata ENSPREP00000015219 76.5363 60.3352 ENSG00000132383 homo_sapiens ENSP00000254719 73.3766 56.9805 poecilia_reticulata ENSPREP00000014993 67.0623 52.0772 ENSG00000132383 homo_sapiens ENSP00000254719 76.7857 60.8766 xiphophorus_maculatus ENSXMAP00000036796 78.8333 62.5 ENSG00000132383 homo_sapiens ENSP00000254719 73.3766 57.4675 xiphophorus_maculatus ENSXMAP00000010389 64.5714 50.5714 ENSG00000132383 homo_sapiens ENSP00000254719 79.0584 62.5 oryzias_latipes ENSORLP00000006118 81.4381 64.3813 ENSG00000132383 homo_sapiens ENSP00000254719 75 56.0065 oryzias_latipes ENSORLP00000004185 70.5343 52.6718 ENSG00000132383 homo_sapiens ENSP00000254719 73.8636 56.3312 cyclopterus_lumpus ENSCLMP00005024252 68.6274 52.3379 ENSG00000132383 homo_sapiens ENSP00000254719 78.8961 62.013 cyclopterus_lumpus ENSCLMP00005017390 81.2709 63.8796 ENSG00000132383 homo_sapiens ENSP00000254719 76.7857 58.4416 oreochromis_niloticus ENSONIP00000027967 71.1278 54.1353 ENSG00000132383 homo_sapiens ENSP00000254719 75.487 60.5519 oreochromis_niloticus ENSONIP00000069956 77.2425 61.9601 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.6623 haplochromis_burtoni ENSHBUP00000031824 81.5615 64.1196 ENSG00000132383 homo_sapiens ENSP00000254719 66.5584 50.8117 haplochromis_burtoni ENSHBUP00000007812 73.6086 56.1939 ENSG00000132383 homo_sapiens ENSP00000254719 75 59.5779 astatotilapia_calliptera ENSACLP00000009741 82.9443 65.8887 ENSG00000132383 homo_sapiens ENSP00000254719 76.1364 58.4416 astatotilapia_calliptera ENSACLP00000007690 73.2812 56.25 ENSG00000132383 homo_sapiens ENSP00000254719 74.513 56.4935 sparus_aurata ENSSAUP00010007432 66.5217 50.4348 ENSG00000132383 homo_sapiens ENSP00000254719 76.9481 60.0649 sparus_aurata ENSSAUP00010012434 76.2058 59.4855 ENSG00000132383 homo_sapiens ENSP00000254719 71.5909 55.0325 lates_calcarifer ENSLCAP00010051821 65.0443 50 ENSG00000132383 homo_sapiens ENSP00000254719 78.7338 62.5 lates_calcarifer ENSLCAP00010003251 80.033 63.5314 ENSG00000132383 homo_sapiens ENSP00000254719 85.2273 72.8896 xenopus_tropicalis ENSXETP00000029655 85.0891 72.7715 ENSG00000132383 homo_sapiens ENSP00000254719 88.7987 76.7857 chrysemys_picta_bellii ENSCPBP00000028886 88.7987 76.7857 ENSG00000132383 homo_sapiens ENSP00000254719 83.9286 70.1299 sphenodon_punctatus ENSSPUP00000009316 88.2253 73.7201 ENSG00000132383 homo_sapiens ENSP00000254719 84.9026 73.3766 crocodylus_porosus ENSCPRP00005022811 81.8466 70.7355 ENSG00000132383 homo_sapiens ENSP00000254719 78.7338 63.961 laticauda_laticaudata ENSLLTP00000012021 61.4702 49.9366 ENSG00000132383 homo_sapiens ENSP00000254719 81.9805 69.1558 pseudonaja_textilis ENSPTXP00000016693 73.6152 62.0991 ENSG00000132383 homo_sapiens ENSP00000254719 69.6429 59.5779 anas_platyrhynchos_platyrhynchos ENSAPLP00000030765 62.6277 53.5766 ENSG00000132383 homo_sapiens ENSP00000254719 85.8766 74.513 gallus_gallus ENSGALP00010043781 85.5987 74.2718 ENSG00000132383 homo_sapiens ENSP00000254719 85.8766 74.513 meleagris_gallopavo ENSMGAP00000005244 86.1563 74.7557 ENSG00000132383 homo_sapiens ENSP00000254719 85.8766 74.3506 serinus_canaria ENSSCAP00000009356 86.2969 74.7145 ENSG00000132383 homo_sapiens ENSP00000254719 85.5519 74.1883 parus_major ENSPMJP00000026035 85.9706 74.5514 ENSG00000132383 homo_sapiens ENSP00000254719 75.487 59.9026 anolis_carolinensis ENSACAP00000038897 67.9825 53.9474 ENSG00000132383 homo_sapiens ENSP00000254719 71.2662 53.8961 neolamprologus_brichardi ENSNBRP00000012421 73.2888 55.4257 ENSG00000132383 homo_sapiens ENSP00000254719 75.3247 59.9026 neolamprologus_brichardi ENSNBRP00000027003 82.4156 65.5417 ENSG00000132383 homo_sapiens ENSP00000254719 74.513 61.526 naja_naja ENSNNAP00000001345 50 41.2854 ENSG00000132383 homo_sapiens ENSP00000254719 77.7597 63.961 podarcis_muralis ENSPMRP00000027887 77.8862 64.065 ENSG00000132383 homo_sapiens ENSP00000254719 84.0909 72.5649 geospiza_fortis ENSGFOP00000006208 86.3333 74.5 ENSG00000132383 homo_sapiens ENSP00000254719 85.7143 73.8636 taeniopygia_guttata ENSTGUP00000005967 86.1338 74.2251 ENSG00000132383 homo_sapiens ENSP00000254719 81.4935 65.9091 erpetoichthys_calabaricus ENSECRP00000012789 82.7018 66.8863 ENSG00000132383 homo_sapiens ENSP00000254719 77.1104 61.3636 kryptolebias_marmoratus ENSKMAP00000007505 77.8689 61.9672 ENSG00000132383 homo_sapiens ENSP00000254719 72.2403 54.0584 kryptolebias_marmoratus ENSKMAP00000000242 73.3114 54.86 ENSG00000132383 homo_sapiens ENSP00000254719 80.3571 64.7727 salvator_merianae ENSSMRP00000009550 79.8387 64.3548 ENSG00000132383 homo_sapiens ENSP00000254719 74.1883 56.6558 oryzias_javanicus ENSOJAP00000043568 67.8042 51.7804 ENSG00000132383 homo_sapiens ENSP00000254719 78.5714 62.3377 oryzias_javanicus ENSOJAP00000040986 78.6992 62.439 ENSG00000132383 homo_sapiens ENSP00000254719 71.4286 55.0325 amphilophus_citrinellus ENSACIP00000016564 74.8299 57.6531 ENSG00000132383 homo_sapiens ENSP00000254719 70.7792 55.0325 amphilophus_citrinellus ENSACIP00000009319 78.8427 61.302 ENSG00000132383 homo_sapiens ENSP00000254719 79.2208 63.474 dicentrarchus_labrax ENSDLAP00005053546 79.7386 63.8889 ENSG00000132383 homo_sapiens ENSP00000254719 74.6753 56.3312 dicentrarchus_labrax ENSDLAP00005057158 69.3816 52.3379 ENSG00000132383 homo_sapiens ENSP00000254719 79.3831 62.3377 amphiprion_percula ENSAPEP00000012151 81.5 64 ENSG00000132383 homo_sapiens ENSP00000254719 75.1623 57.1429 amphiprion_percula ENSAPEP00000026917 69.7289 53.012 ENSG00000132383 homo_sapiens ENSP00000254719 75.1623 58.6039 oryzias_sinensis ENSOSIP00000035842 78.6078 61.2903 ENSG00000132383 homo_sapiens ENSP00000254719 74.3506 55.8442 oryzias_sinensis ENSOSIP00000011182 71.2286 53.4992 ENSG00000132383 homo_sapiens ENSP00000254719 86.6883 74.8377 pelodiscus_sinensis ENSPSIP00000017664 88.5572 76.4511 ENSG00000132383 homo_sapiens ENSP00000254719 89.1234 76.7857 gopherus_evgoodei ENSGEVP00005012221 89.1234 76.7857 ENSG00000132383 homo_sapiens ENSP00000254719 88.961 76.2987 chelonoidis_abingdonii ENSCABP00000028275 88.961 76.2987 ENSG00000132383 homo_sapiens ENSP00000254719 75.8117 57.9545 seriola_dumerili ENSSDUP00000022462 68.6765 52.5 ENSG00000132383 homo_sapiens ENSP00000254719 78.7338 63.474 seriola_dumerili ENSSDUP00000016384 80.8333 65.1667 ENSG00000132383 homo_sapiens ENSP00000254719 74.3506 55.6818 cottoperca_gobio ENSCGOP00000004382 69.0799 51.7345 ENSG00000132383 homo_sapiens ENSP00000254719 76.6234 60.8766 cottoperca_gobio ENSCGOP00000053222 77.2504 61.3748 ENSG00000132383 homo_sapiens ENSP00000254719 84.4156 73.3766 struthio_camelus_australis ENSSCUP00000012547 86.5225 75.208 ENSG00000132383 homo_sapiens ENSP00000254719 85.8766 73.7013 anser_brachyrhynchus ENSABRP00000012703 78.0236 66.9617 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 60.3896 gasterosteus_aculeatus ENSGACP00000014376 80.2326 61.794 ENSG00000132383 homo_sapiens ENSP00000254719 73.2143 55.0325 gasterosteus_aculeatus ENSGACP00000027137 73.9344 55.5738 ENSG00000132383 homo_sapiens ENSP00000254719 69.9675 51.9481 cynoglossus_semilaevis ENSCSEP00000019947 68.0885 50.5529 ENSG00000132383 homo_sapiens ENSP00000254719 78.2467 60.3896 cynoglossus_semilaevis ENSCSEP00000020488 79.4069 61.285 ENSG00000132383 homo_sapiens ENSP00000254719 77.7597 62.1753 poecilia_formosa ENSPFOP00000004158 79.8333 63.8333 ENSG00000132383 homo_sapiens ENSP00000254719 66.0714 51.461 poecilia_formosa ENSPFOP00000012296 68.8663 53.6379 ENSG00000132383 homo_sapiens ENSP00000254719 74.513 57.7922 myripristis_murdjan ENSMMDP00005023734 75.2459 58.3607 ENSG00000132383 homo_sapiens ENSP00000254719 74.1883 57.7922 myripristis_murdjan ENSMMDP00005010214 74.43 57.9805 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 62.1753 sander_lucioperca ENSSLUP00000059588 79.9669 63.4106 ENSG00000132383 homo_sapiens ENSP00000254719 72.5649 54.8701 sander_lucioperca ENSSLUP00000019936 65.5425 49.5601 ENSG00000132383 homo_sapiens ENSP00000254719 86.039 75 strigops_habroptila ENSSHBP00005007350 86.3192 75.2443 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.3377 amphiprion_ocellaris ENSAOCP00000018205 81.8333 64 ENSG00000132383 homo_sapiens ENSP00000254719 74.3506 56.4935 amphiprion_ocellaris ENSAOCP00000005492 70.5701 53.621 ENSG00000132383 homo_sapiens ENSP00000254719 71.9156 62.013 terrapene_carolina_triunguis ENSTMTP00000013706 86.1868 74.3191 ENSG00000132383 homo_sapiens ENSP00000254719 21.1039 13.7987 hucho_hucho ENSHHUP00000021870 61.6114 40.2844 ENSG00000132383 homo_sapiens ENSP00000254719 75.974 58.9286 hucho_hucho ENSHHUP00000067512 76.4706 59.3137 ENSG00000132383 homo_sapiens ENSP00000254719 79.8701 62.1753 hucho_hucho ENSHHUP00000036832 80.9211 62.9934 ENSG00000132383 homo_sapiens ENSP00000254719 75.6494 57.3052 betta_splendens ENSBSLP00000010998 69.037 52.2963 ENSG00000132383 homo_sapiens ENSP00000254719 79.2208 62.8247 betta_splendens ENSBSLP00000027088 55.5176 44.0273 ENSG00000132383 homo_sapiens ENSP00000254719 71.5909 53.4091 pygocentrus_nattereri ENSPNAP00000002042 74.3676 55.4806 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 62.3377 anabas_testudineus ENSATEP00000070621 77.7778 61.8358 ENSG00000132383 homo_sapiens ENSP00000254719 74.513 56.6558 anabas_testudineus ENSATEP00000009151 70.5069 53.6098 ENSG00000132383 homo_sapiens ENSP00000254719 53.8961 31.4935 saccharomyces_cerevisiae YAR007C 53.4622 31.2399 ENSG00000132383 homo_sapiens ENSP00000254719 78.8961 63.6364 seriola_lalandi_dorsalis ENSSLDP00000014815 81 65.3333 ENSG00000132383 homo_sapiens ENSP00000254719 75.3247 57.6299 seriola_lalandi_dorsalis ENSSLDP00000026752 67.7372 51.8248 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 61.2013 labrus_bergylta ENSLBEP00000028522 79.8347 62.314 ENSG00000132383 homo_sapiens ENSP00000254719 74.8377 55.5195 labrus_bergylta ENSLBEP00000002897 65.3901 48.5106 ENSG00000132383 homo_sapiens ENSP00000254719 75.974 58.1169 pundamilia_nyererei ENSPNYP00000032019 73.125 55.9375 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.8247 pundamilia_nyererei ENSPNYP00000021640 81.5615 64.2857 ENSG00000132383 homo_sapiens ENSP00000254719 75.3247 56.8182 mastacembelus_armatus ENSMAMP00000029820 69.0476 52.0833 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 62.8247 mastacembelus_armatus ENSMAMP00000026798 81.5615 64.2857 ENSG00000132383 homo_sapiens ENSP00000254719 72.0779 55.5195 stegastes_partitus ENSSPAP00000014932 74.3719 57.2864 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 62.5 stegastes_partitus ENSSPAP00000013058 81.6667 64.1667 ENSG00000132383 homo_sapiens ENSP00000254719 73.8636 57.4675 oncorhynchus_tshawytscha ENSOTSP00005082754 74.8355 58.2237 ENSG00000132383 homo_sapiens ENSP00000254719 79.7078 61.8507 oncorhynchus_tshawytscha ENSOTSP00005011910 80.8896 62.7677 ENSG00000132383 homo_sapiens ENSP00000254719 51.9481 39.9351 oncorhynchus_tshawytscha ENSOTSP00005049696 69.1145 53.1317 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 62.5 acanthochromis_polyacanthus ENSAPOP00000009339 81.6667 64.1667 ENSG00000132383 homo_sapiens ENSP00000254719 75 56.4935 acanthochromis_polyacanthus ENSAPOP00000031867 66.8596 50.3618 ENSG00000132383 homo_sapiens ENSP00000254719 85.7143 75 aquila_chrysaetos_chrysaetos ENSACCP00020007861 85.8537 75.1219 ENSG00000132383 homo_sapiens ENSP00000254719 71.4286 54.2208 nothobranchius_furzeri ENSNFUP00015043742 59.7826 45.3804 ENSG00000132383 homo_sapiens ENSP00000254719 78.5714 62.8247 nothobranchius_furzeri ENSNFUP00015004695 80.1325 64.0728 ENSG00000132383 homo_sapiens ENSP00000254719 71.5909 55.8442 cyprinodon_variegatus ENSCVAP00000011210 65.8209 51.3433 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 62.8247 cyprinodon_variegatus ENSCVAP00000016427 79.703 63.8614 ENSG00000132383 homo_sapiens ENSP00000254719 76.461 59.0909 denticeps_clupeoides ENSDCDP00000040600 76.7101 59.2834 ENSG00000132383 homo_sapiens ENSP00000254719 77.2727 60.2273 larimichthys_crocea ENSLCRP00005011057 73.5703 57.3416 ENSG00000132383 homo_sapiens ENSP00000254719 74.3506 56.1688 larimichthys_crocea ENSLCRP00005003934 68.9759 52.1084 ENSG00000132383 homo_sapiens ENSP00000254719 78.5714 62.3377 takifugu_rubripes ENSTRUP00000008475 80.6667 64 ENSG00000132383 homo_sapiens ENSP00000254719 73.0519 54.3831 takifugu_rubripes ENSTRUP00000000950 63.1136 46.9846 ENSG00000132383 homo_sapiens ENSP00000254719 86.039 74.513 ficedula_albicollis ENSFALP00000006871 86.46 74.8776 ENSG00000132383 homo_sapiens ENSP00000254719 58.1169 43.5065 hippocampus_comes ENSHCOP00000009787 62.5874 46.8531 ENSG00000132383 homo_sapiens ENSP00000254719 76.6234 60.3896 hippocampus_comes ENSHCOP00000000570 77.2504 60.8838 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 62.987 cyprinus_carpio_carpio ENSCCRP00000031159 78.7781 62.3794 ENSG00000132383 homo_sapiens ENSP00000254719 75.974 60.0649 cyprinus_carpio_carpio ENSCCRP00000155916 51.8272 40.9745 ENSG00000132383 homo_sapiens ENSP00000254719 83.4416 71.7533 coturnix_japonica ENSCJPP00005013377 78.8344 67.7914 ENSG00000132383 homo_sapiens ENSP00000254719 69.9675 54.3831 poecilia_latipinna ENSPLAP00000023462 67.6609 52.5903 ENSG00000132383 homo_sapiens ENSP00000254719 77.5974 61.8507 poecilia_latipinna ENSPLAP00000003506 79.6667 63.5 ENSG00000132383 homo_sapiens ENSP00000254719 76.9481 60.8766 sinocyclocheilus_grahami ENSSGRP00000010771 78.607 62.1891 ENSG00000132383 homo_sapiens ENSP00000254719 78.4091 61.3636 sinocyclocheilus_grahami ENSSGRP00000075795 75.351 58.9704 ENSG00000132383 homo_sapiens ENSP00000254719 76.1364 58.4416 maylandia_zebra ENSMZEP00005033154 73.2812 56.25 ENSG00000132383 homo_sapiens ENSP00000254719 79.5455 62.6623 maylandia_zebra ENSMZEP00005010000 81.3953 64.1196 ENSG00000132383 homo_sapiens ENSP00000254719 79.8701 63.7987 tetraodon_nigroviridis ENSTNIP00000019292 80.261 64.1109 ENSG00000132383 homo_sapiens ENSP00000254719 71.1039 52.9221 tetraodon_nigroviridis ENSTNIP00000019258 72.6368 54.063 ENSG00000132383 homo_sapiens ENSP00000254719 77.5974 60.5519 paramormyrops_kingsleyae ENSPKIP00000025037 78.3607 61.1475 ENSG00000132383 homo_sapiens ENSP00000254719 79.8701 64.9351 scleropages_formosus ENSSFOP00015008168 76.2791 62.0155 ENSG00000132383 homo_sapiens ENSP00000254719 85.0649 72.8896 leptobrachium_leishanense ENSLLEP00000016672 85.4812 73.2463 ENSG00000132383 homo_sapiens ENSP00000254719 75.974 59.7403 scophthalmus_maximus ENSSMAP00000055212 73.2394 57.59 ENSG00000132383 homo_sapiens ENSP00000254719 73.8636 56.0065 scophthalmus_maximus ENSSMAP00000064773 67.8092 51.4158 ENSG00000132383 homo_sapiens ENSP00000254719 78.2467 60.5519 oryzias_melastigma ENSOMEP00000003762 80.602 62.3746 ENSG00000132383 homo_sapiens ENSP00000254719 72.5649 55.6818 oryzias_melastigma ENSOMEP00000009748 68.8752 52.8505
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000723 involved_in telomere maintenance 3 IC,IMP,NAS Homo_sapiens(9606) Process GO:0000724 involved_in double-strand break repair via homologous recombination 3 IBA,IMP,NAS Homo_sapiens(9606) Process GO:0000781 located_in chromosome, telomeric region 1 HDA Homo_sapiens(9606) Component GO:0003684 enables damaged DNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0003697 enables single-stranded DNA binding 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005662 part_of DNA replication factor A complex 3 IBA,IDA,IPI Homo_sapiens(9606) Component GO:0006260 involved_in DNA replication 2 IMP,NAS Homo_sapiens(9606) Process GO:0006261 involved_in DNA-templated DNA replication 1 TAS Homo_sapiens(9606) Process GO:0006281 involved_in DNA repair 2 IDA,IMP Homo_sapiens(9606) Process GO:0006284 involved_in base-excision repair 1 IDA Homo_sapiens(9606) Process GO:0006289 involved_in nucleotide-excision repair 3 IBA,IMP,NAS Homo_sapiens(9606) Process GO:0006298 involved_in mismatch repair 1 IMP Homo_sapiens(9606) Process GO:0006310 involved_in DNA recombination 1 TAS Homo_sapiens(9606) Process GO:0006974 involved_in DNA damage response 1 IMP Homo_sapiens(9606) Process GO:0007004 involved_in telomere maintenance via telomerase 1 IBA Homo_sapiens(9606) Process GO:0016605 colocalizes_with PML body 2 IDA Homo_sapiens(9606) Component GO:0034502 involved_in protein localization to chromosome 1 IDA Homo_sapiens(9606) Process GO:0043047 enables single-stranded telomeric DNA binding 1 IBA Homo_sapiens(9606) Function GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0051321 involved_in meiotic cell cycle 1 IBA Homo_sapiens(9606) Process GO:0090734 located_in site of DNA damage 1 IMP Homo_sapiens(9606) Component GO:0098505 enables G-rich strand telomeric DNA binding 2 IDA,IMP Homo_sapiens(9606) Function
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
