Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-bodyNucleoli
BulkPerturb-seq DataSet_01_171 DataSet_01_174

Description

Ensembl ID ENSG00000129351 Gene ID 3609 Accession 6038
Symbol ILF3 Alias CBTF;DRBF;MMP4;MPP4;NF90;NFAR;NF110;NF90a;NF90b;NF90c;NFAR2;TCP80;DRBP76;NF110b;NFAR-1;NFAR-2;NFAR90;TCP110;MPP4110;NF90ctv;NFAR110;MPHOSPH4;NF-AT-90 Full Name interleukin enhancer binding factor 3
Status Confidence Length 38055 bases Strand Plus strand
Position 19 : 10654346 - 10692400 RNA binding domain dsrm , DZF
Summary This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000250241 dsrm PF00035 5.1e-24 1
ENSP00000250241 dsrm PF00035 5.1e-24 2
ENSP00000250241 DZF PF07528 3.4e-108 3
ENSP00000465515 dsrm PF00035 5.2e-24 1
ENSP00000465515 dsrm PF00035 5.2e-24 2
ENSP00000465515 DZF PF07528 3.4e-108 3
ENSP00000465219 dsrm PF00035 5.4e-24 1
ENSP00000465219 dsrm PF00035 5.4e-24 2
ENSP00000465219 DZF PF07528 3.5e-108 3
ENSP00000384660 dsrm PF00035 5.4e-24 1
ENSP00000384660 dsrm PF00035 5.4e-24 2
ENSP00000384660 DZF PF07528 3.5e-108 3
ENSP00000468156 dsrm PF00035 7.7e-24 1
ENSP00000468156 dsrm PF00035 7.7e-24 2
ENSP00000468156 DZF PF07528 5.9e-108 3
ENSP00000468181 dsrm PF00035 7.7e-24 1
ENSP00000468181 dsrm PF00035 7.7e-24 2
ENSP00000468181 DZF PF07528 5.9e-108 3
ENSP00000467950 DZF PF07528 2.7e-69 1
ENSP00000465654 DZF PF07528 3.6e-63 1
ENSP00000465831 DZF PF07528 5.9e-28 1
ENSP00000468134 DZF PF07528 9.9e-17 1
ENSP00000467372 DZF PF07528 2.1e-06 1
ENSP00000464974 DZF PF07528 5.9e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
33043604 Long non-coding RNA ELDR enhances oral cancer growth by promoting ILF3-cyclin E1 signaling. Subhayan Sur 2020-12-03 EMBO reports
34274947 The ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA-RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis. Dandan Li 2021-09-01 Oncogene
36973424 E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA. Hao-Ming Shen 2023-07-01 Cancer gene therapy
15254228 Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5. Ting Chen 2004-08-01 Molecular and cellular biology
11777942 Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins. M Amy Brownawell 2002-01-07 The Journal of cell biology
35637192 A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA. Kevin K Van 2022-05-30 Nature communications
33885378 circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA. Ying Ma 2021-04-22 Aging
23143594 Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. C Lam Tsoi 2012-12-01 Nature genetics
31777917 PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis. Valeria Spadotto 2020-01-10 Nucleic acids research
26256788 The yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNA. You Li 2015-09-01 Nature reviews. Microbiology
23321469 Proteomic analysis of interleukin enhancer binding factor 3 (Ilf3) and nuclear factor 90 (NF90) interactome. Alexandre Chaumet 2013-06-01 Biochimie
36755301 Metabolic reprogramming in colorectal cancer: regulatory networks and therapy. Jieping Zhang 2023-02-08 Cell & bioscience
29321585 Site-specific randomization of the endogenous genome by a regulatable CRISPR-Cas9 piggyBac system in human cells. Kentaro Ishida 2018-01-10 Scientific reports
33922141 Retrotransposons as Drivers of Mammalian Brain Evolution. Roberto Ferrari 2021-04-22 Life (Basel, Switzerland)
30588088 The positive feedback loop between ILF3 and lncRNA ILF3-AS1 promotes melanoma proliferation, migration, and invasion. Guozhen Gao 2018-01-01 Cancer management and research
29547715 Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels. K Julia Nussbacher 2018-03-15 Molecular cell
21846828 Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. Eric Bortz 2011-01-01 mBio
31570000 The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs. Francesca Fasolo 2019-12-01 FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Transcripts

Name Transcript ID bp Protein Translation ID
ILF3-207 ENST00000587928 4230 No protein -
ILF3-202 ENST00000407004 3653 706aa ENSP00000384660
ILF3-216 ENST00000589998 3641 702aa ENSP00000465219
ILF3-209 ENST00000588657 6017 898aa ENSP00000468181
ILF3-215 ENST00000589600 839 161aa ENSP00000468134
ILF3-212 ENST00000589283 599 99aa ENSP00000466396
ILF3-217 ENST00000590009 953 254aa ENSP00000465654
ILF3-223 ENST00000593199 413 77aa ENSP00000468323
ILF3-205 ENST00000587505 791 79aa ENSP00000466991
ILF3-210 ENST00000589052 637 79aa ENSP00000468092
ILF3-201 ENST00000250241 3035 690aa ENSP00000250241
ILF3-221 ENST00000592763 3866 698aa ENSP00000465515
ILF3-218 ENST00000590261 3219 894aa ENSP00000468156
ILF3-208 ENST00000587941 533 122aa ENSP00000464974
ILF3-206 ENST00000587840 655 55aa ENSP00000467704
ILF3-213 ENST00000589416 773 158aa ENSP00000465831
ILF3-203 ENST00000585835 849 180aa ENSP00000467950
ILF3-214 ENST00000589485 620 73aa ENSP00000467372
ILF3-211 ENST00000589173 570 No protein -
ILF3-222 ENST00000593061 475 113aa ENSP00000466724
ILF3-219 ENST00000590869 531 116aa ENSP00000466235
ILF3-220 ENST00000591649 2579 No protein -
ILF3-204 ENST00000586544 3859 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
68197Body Height2E-1625429064
80066Body Height8E-1125282103
81639Triglycerides7E-623251661

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000129351homo_sapiensENSP0000045750122.5112.1514homo_sapiensENSP0000046818112.58356.79287
ENSG00000129351homo_sapiensENSP0000026506924.208617.784homo_sapiensENSP0000046818128.953221.2695
ENSG00000129351homo_sapiensENSP0000032134775.148859.9702homo_sapiensENSP0000046818156.236144.8775
ENSG00000129351homo_sapiensENSP0000035501135.384619.7436homo_sapiensENSP0000046818115.36758.57461
ENSG00000129351homo_sapiensENSP0000001587716.83319.41512homo_sapiensENSP0000046818113.14037.34967
ENSG00000129351homo_sapiensENSP0000026296127.795520.1278homo_sapiensENSP0000046818129.064621.0468
ENSG00000129351homo_sapiensENSP0000032515318.524911.6638homo_sapiensENSP0000046818112.02677.57238
ENSG00000129351homo_sapiensENSP0000029651318.40289.375homo_sapiensENSP0000046818111.8046.01336
ENSG00000129351homo_sapiensENSP0000036092216.63789.18544homo_sapiensENSP0000046818110.69045.902
ENSG00000129351homo_sapiensENSP0000037071314.61438.93099homo_sapiensENSP0000046818112.02677.34967
ENSG00000129351homo_sapiensENSP0000031817619.488811.1821homo_sapiensENSP000004681816.792873.89755
ENSG00000129351homo_sapiensENSP0000042875617.1938.77193homo_sapiensENSP0000046818110.91315.56793
ENSG00000129351homo_sapiensENSP000003574599.38015.79119homo_sapiensENSP0000046818112.80627.90646
ENSG00000129351homo_sapiensENSP0000026698720.218612.8415homo_sapiensENSP000004681818.240535.23385

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000129351homo_sapiensENSP0000046818197.550197.216nomascus_leucogenysENSNLEP0000001497398.871398.5327
ENSG00000129351homo_sapiensENSP0000046818199.777399.6659pan_paniscusENSPPAP0000003581899.777399.6659
ENSG00000129351homo_sapiensENSP0000046818194.543494.4321pongo_abeliiENSPPYP0000002409499.76599.6475
ENSG00000129351homo_sapiensENSP0000046818199.777399.6659pan_troglodytesENSPTRP0000007924199.777399.6659
ENSG00000129351homo_sapiensENSP0000046818199.888699.7773gorilla_gorillaENSGGOP0000000406999.888699.7773
ENSG00000129351homo_sapiensENSP0000046818193.095888.0846ornithorhynchus_anatinusENSOANP0000003694893.199688.1828
ENSG00000129351homo_sapiensENSP0000046818180.623671.1581ornithorhynchus_anatinusENSOANP0000004219983.122873.364
ENSG00000129351homo_sapiensENSP0000046818175.389872.049sarcophilus_harrisiiENSSHAP0000002804495.756791.5134
ENSG00000129351homo_sapiensENSP0000046818164.810763.029notamacropus_eugeniiENSMEUP0000001157176.478374.3758
ENSG00000129351homo_sapiensENSP0000046818166.926563.5857choloepus_hoffmanniENSCHOP0000000177468.529165.1083
ENSG00000129351homo_sapiensENSP0000046818198.886496.9933dasypus_novemcinctusENSDNOP0000000195398.557296.6704
ENSG00000129351homo_sapiensENSP0000046818176.837475.7238echinops_telfairiENSETEP0000001277097.595596.181
ENSG00000129351homo_sapiensENSP0000046818199.665999.2205callithrix_jacchusENSCJAP0000001195299.555199.1101
ENSG00000129351homo_sapiensENSP0000046818199.665999.5546cercocebus_atysENSCATP0000000792999.555199.4438
ENSG00000129351homo_sapiensENSP0000046818199.777399.6659macaca_fascicularisENSMFAP0000004505599.777399.6659
ENSG00000129351homo_sapiensENSP0000046818199.665999.5546macaca_mulattaENSMMUP0000001925399.555199.4438
ENSG00000129351homo_sapiensENSP0000046818199.665999.5546macaca_nemestrinaENSMNEP0000003985799.555199.4438
ENSG00000129351homo_sapiensENSP0000046818199.777399.6659papio_anubisENSPANP0000003322699.777399.6659
ENSG00000129351homo_sapiensENSP0000046818197.550197.216mandrillus_leucophaeusENSMLEP0000003757398.98398.6441
ENSG00000129351homo_sapiensENSP0000046818185.746184.4098tursiops_truncatusENSTTRP0000001576886.322984.9776
ENSG00000129351homo_sapiensENSP0000046818198.552397.4388vulpes_vulpesENSVVUP0000002384998.772397.6562
ENSG00000129351homo_sapiensENSP0000046818195.879793.2071mus_spretusMGP_SPRETEiJ_P009050895.879793.2071
ENSG00000129351homo_sapiensENSP0000046818197.661595.9911equus_asinusENSEASP0000501221396.479694.8295
ENSG00000129351homo_sapiensENSP0000046818198.552396.882capra_hircusENSCHIP0000002972698.442796.7742
ENSG00000129351homo_sapiensENSP0000046818198.552397.216loxodonta_africanaENSLAFP0000001779398.333397
ENSG00000129351homo_sapiensENSP0000046818195.768493.7639panthera_leoENSPLOP0000000545787.576485.7434
ENSG00000129351homo_sapiensENSP0000046818198.886497.7728ailuropoda_melanoleucaENSAMEP0000001179398.666797.5556
ENSG00000129351homo_sapiensENSP0000046818197.884296.2138bos_indicus_hybridENSBIXP0000502484298.212396.5363
ENSG00000129351homo_sapiensENSP0000046818198.218396.6592oryctolagus_cuniculusENSOCUP0000001203298.10996.5517
ENSG00000129351homo_sapiensENSP0000046818198.106996.5479equus_caballusENSECAP0000001571497.997896.4405
ENSG00000129351homo_sapiensENSP0000046818198.552397.4388canis_lupus_familiarisENSCAFP0084503351298.772397.6562
ENSG00000129351homo_sapiensENSP0000046818198.886497.6615panthera_pardusENSPPRP0000002855898.666797.4444
ENSG00000129351homo_sapiensENSP0000046818197.995596.882marmota_marmota_marmotaENSMMMP0000002224396.809795.7096
ENSG00000129351homo_sapiensENSP0000046818198.44196.7706balaenoptera_musculusENSBMSP0001001535898.550796.8785
ENSG00000129351homo_sapiensENSP0000046818197.661596.4365cavia_porcellusENSCPOP0000001236497.988896.7598
ENSG00000129351homo_sapiensENSP0000046818198.775197.5501felis_catusENSFCAP0000000451998.555697.3333
ENSG00000129351homo_sapiensENSP0000046818198.329697.216ursus_americanusENSUAMP0000002341097.139796.0396
ENSG00000129351homo_sapiensENSP0000046818196.436593.2071monodelphis_domesticaENSMODP0000000731496.008992.7938
ENSG00000129351homo_sapiensENSP0000046818198.329696.6592bison_bison_bisonENSBBBP0000000784898.220296.5517
ENSG00000129351homo_sapiensENSP0000046818198.997897.4388monodon_monocerosENSMMNP0001500140198.668197.1143
ENSG00000129351homo_sapiensENSP0000046818192.204989.6437sus_scrofaENSSSCP0000002861297.526594.8174
ENSG00000129351homo_sapiensENSP0000046818198.663797.8842microcebus_murinusENSMICP0000000885698.117497.3422
ENSG00000129351homo_sapiensENSP0000046818182.962181.5145octodon_degusENSODEP0000002168596.502694.8186
ENSG00000129351homo_sapiensENSP0000046818170.044564.588jaculus_jaculusENSJJAP0000001942283.866777.3333
ENSG00000129351homo_sapiensENSP0000046818175.278473.8307jaculus_jaculusENSJJAP0000000905496.433794.5792
ENSG00000129351homo_sapiensENSP0000046818198.552396.882ovis_aries_rambouilletENSOARP0002000819198.442796.7742
ENSG00000129351homo_sapiensENSP0000046818176.837475.7238ursus_maritimusENSUMAP0000003478698.290696.8661
ENSG00000129351homo_sapiensENSP0000046818195.991193.7639ochotona_princepsENSOPRP0000001369796.745294.5006
ENSG00000129351homo_sapiensENSP0000046818198.552396.9933delphinapterus_leucasENSDLEP0000001070198.662297.1014
ENSG00000129351homo_sapiensENSP0000046818195.65793.4298physeter_catodonENSPCTP0000500903497.502895.2327
ENSG00000129351homo_sapiensENSP0000046818195.768493.0958mus_caroliMGP_CAROLIEiJ_P008695395.875193.1996
ENSG00000129351homo_sapiensENSP0000046818195.768492.9844mus_musculusENSMUSP0000014948394.401891.6575
ENSG00000129351homo_sapiensENSP0000046818175.946574.0535dipodomys_ordiiENSDORP0000001433897.15194.7293
ENSG00000129351homo_sapiensENSP0000046818198.329696.9933mustela_putorius_furoENSMPUP0000000615298.549197.2098
ENSG00000129351homo_sapiensENSP0000046818199.220598.7751aotus_nancymaaeENSANAP0000001807999.220598.7751
ENSG00000129351homo_sapiensENSP0000046818199.443298.9978saimiri_boliviensis_boliviensisENSSBOP0000002283699.332698.8876
ENSG00000129351homo_sapiensENSP0000046818185.746184.5212vicugna_pacosENSVPAP0000000845886.226284.9944
ENSG00000129351homo_sapiensENSP0000046818178.062477.5056chlorocebus_sabaeusENSCSAP0000000326499.291898.5836
ENSG00000129351homo_sapiensENSP0000046818195.879793.4298mesocricetus_auratusENSMAUP0000002320796.093893.6384
ENSG00000129351homo_sapiensENSP0000046818198.552396.9933phocoena_sinusENSPSNP0000000034198.662297.1014
ENSG00000129351homo_sapiensENSP0000046818198.886497.6615camelus_dromedariusENSCDRP0000501222798.666797.4444
ENSG00000129351homo_sapiensENSP0000046818198.44197.3274carlito_syrichtaENSTSYP0000002496298.331597.2191
ENSG00000129351homo_sapiensENSP0000046818198.775197.5501panthera_tigris_altaicaENSPTIP0000002610198.555697.3333
ENSG00000129351homo_sapiensENSP0000046818195.65793.0958rattus_norvegicusENSRNOP0000007236995.232892.6829
ENSG00000129351homo_sapiensENSP0000046818198.886498.3296prolemur_simusENSPSMP0000002295498.666798.1111
ENSG00000129351homo_sapiensENSP0000046818195.768492.9844microtus_ochrogasterENSMOCP0000002136696.089493.2961
ENSG00000129351homo_sapiensENSP0000046818182.182678.5078sorex_araneusENSSARP0000000663383.014679.3026
ENSG00000129351homo_sapiensENSP0000046818114.253913.6971peromyscus_maniculatus_bairdiiENSPEMP0000003089591.428687.8571
ENSG00000129351homo_sapiensENSP0000046818169.376467.706peromyscus_maniculatus_bairdiiENSPEMP0000000068572.695470.9452
ENSG00000129351homo_sapiensENSP0000046818197.772896.1024bos_mutusENSBMUP0000000542897.664195.9956
ENSG00000129351homo_sapiensENSP0000046818195.545792.8731mus_spicilegusENSMSIP0000001915594.182291.5478
ENSG00000129351homo_sapiensENSP0000046818195.768493.2071cricetulus_griseus_chok1gshdENSCGRP0000102332694.609592.0792
ENSG00000129351homo_sapiensENSP0000046818188.975587.1938pteropus_vampyrusENSPVAP0000001145589.473787.682
ENSG00000129351homo_sapiensENSP0000046818197.21695.3229myotis_lucifugusENSMLUP0000000763897.43395.5357
ENSG00000129351homo_sapiensENSP0000046818196.436593.2071vombatus_ursinusENSVURP0001003274196.008992.7938
ENSG00000129351homo_sapiensENSP0000046818198.106996.5479rhinolophus_ferrumequinumENSRFEP0001002085797.780296.2264
ENSG00000129351homo_sapiensENSP0000046818198.775197.4388neovison_visonENSNVIP0000000051098.555697.2222
ENSG00000129351homo_sapiensENSP0000046818198.329696.6592bos_taurusENSBTAP0000001881898.220296.5517
ENSG00000129351homo_sapiensENSP0000046818176.280675.167heterocephalus_glaber_femaleENSHGLP0000002740695.804294.4056
ENSG00000129351homo_sapiensENSP0000046818120.824119.9332heterocephalus_glaber_femaleENSHGLP0000002146388.625684.8341
ENSG00000129351homo_sapiensENSP0000046818199.777399.5546rhinopithecus_bietiENSRBIP0000002995699.777399.5546
ENSG00000129351homo_sapiensENSP0000046818198.997897.8842canis_lupus_dingoENSCAFP0002003138798.777897.6667
ENSG00000129351homo_sapiensENSP0000046818198.775197.8842sciurus_vulgarisENSSVLP0000502741498.555697.6667
ENSG00000129351homo_sapiensENSP0000046818195.65791.7595phascolarctos_cinereusENSPCIP0000002029289.853686.1925
ENSG00000129351homo_sapiensENSP0000046818193.652692.2049procavia_capensisENSPCAP0000000313393.966592.514
ENSG00000129351homo_sapiensENSP0000046818158.240554.7884nannospalax_galiliENSNGAP0000001364087.751782.5503
ENSG00000129351homo_sapiensENSP0000046818195.879793.5412nannospalax_galiliENSNGAP0000000660096.201193.8548
ENSG00000129351homo_sapiensENSP0000046818176.726175.0557bos_grunniensENSBGRP0000000654497.869395.7386
ENSG00000129351homo_sapiensENSP0000046818197.884296.7706chinchilla_lanigeraENSCLAP0000001681598.212397.095
ENSG00000129351homo_sapiensENSP0000046818198.44196.6592cervus_hanglu_yarkandensisENSCHYP0000000384798.331596.5517
ENSG00000129351homo_sapiensENSP0000046818196.659293.9866catagonus_wagneriENSCWAP0000002626597.418694.725
ENSG00000129351homo_sapiensENSP0000046818197.884296.882ictidomys_tridecemlineatusENSSTOP0000002688698.102797.0982
ENSG00000129351homo_sapiensENSP0000046818198.218397.4388otolemur_garnettiiENSOGAP0000001365498.218397.4388
ENSG00000129351homo_sapiensENSP0000046818164.699360.8018otolemur_garnettiiENSOGAP0000001913088.567183.2317
ENSG00000129351homo_sapiensENSP0000046818195.768493.9866cebus_imitatorENSCCAP0000000467393.886592.1397
ENSG00000129351homo_sapiensENSP0000046818198.218397.216urocitellus_parryiiENSUPAP0001000288196.604695.6188
ENSG00000129351homo_sapiensENSP0000046818198.218396.5479moschus_moschiferusENSMMSP0000000059898.10996.4405
ENSG00000129351homo_sapiensENSP0000046818199.777399.5546rhinopithecus_roxellanaENSRROP0000001507399.777399.5546
ENSG00000129351homo_sapiensENSP0000046818195.65793.0958mus_pahariMGP_PahariEiJ_P002260295.65793.0958
ENSG00000129351homo_sapiensENSP0000046818199.220598.7751propithecus_coquereliENSPCOP000000157229998.5556
ENSG00000129351homo_sapiensENSP0000046818119.376411.9154caenorhabditis_elegansY95B8A.8.122.774914.0052
ENSG00000129351homo_sapiensENSP0000046818112.58357.12695drosophila_melanogasterFBpp008007624.301113.7634
ENSG00000129351homo_sapiensENSP000004681819.465485.79065drosophila_melanogasterFBpp007685626.234616.0494
ENSG00000129351homo_sapiensENSP000004681819.354125.23385drosophila_melanogasterFBpp007321928.378415.8784
ENSG00000129351homo_sapiensENSP0000046818126.280618.7082drosophila_melanogasterFBpp030548926.696819.0045
ENSG00000129351homo_sapiensENSP000004681817.79514.45434ciona_intestinalisENSCINP0000001280523.333313.3333
ENSG00000129351homo_sapiensENSP0000046818123.051215.3675ciona_intestinalisENSCINP0000003451855.49636.9973
ENSG00000129351homo_sapiensENSP0000046818123.830717.2606ciona_intestinalisENSCINP0000001004622.597716.3675
ENSG00000129351homo_sapiensENSP0000046818122.828516.0356ciona_intestinalisENSCINP0000002604224.580317.2662
ENSG00000129351homo_sapiensENSP0000046818159.354152.1158callorhinchus_miliiENSCMIP0000001082986.666776.0976
ENSG00000129351homo_sapiensENSP0000046818182.739473.7194latimeria_chalumnaeENSLACP0000000428182.281373.3112
ENSG00000129351homo_sapiensENSP0000046818177.95168.7082lepisosteus_oculatusENSLOCP0000001025969.101760.9082
ENSG00000129351homo_sapiensENSP0000046818173.496763.8085clupea_harengusENSCHAP0000003202377.830267.5708
ENSG00000129351homo_sapiensENSP0000046818171.158162.8062danio_rerioENSDARP0000014080976.710767.7071
ENSG00000129351homo_sapiensENSP0000046818171.826363.4744carassius_auratusENSCARP0000005444876.421867.5355
ENSG00000129351homo_sapiensENSP0000046818171.380862.6949carassius_auratusENSCARP0000012806576.491667.1838
ENSG00000129351homo_sapiensENSP0000046818173.051264.1425astyanax_mexicanusENSAMXP0000005290376.456967.1329
ENSG00000129351homo_sapiensENSP0000046818171.937663.8085ictalurus_punctatusENSIPUP0000001115475.732767.1747
ENSG00000129351homo_sapiensENSP0000046818173.60863.9198esox_luciusENSELUP0000000966175.715965.7503
ENSG00000129351homo_sapiensENSP0000046818172.383162.3608electrophorus_electricusENSEEEP0000003956475.231564.8148
ENSG00000129351homo_sapiensENSP0000046818171.826361.5813oncorhynchus_kisutchENSOKIP0000503187876.421865.5213
ENSG00000129351homo_sapiensENSP0000046818171.714961.804oncorhynchus_kisutchENSOKIP0000502120376.484665.9145
ENSG00000129351homo_sapiensENSP0000046818171.492261.4699oncorhynchus_mykissENSOMYP0000000760976.066465.4028
ENSG00000129351homo_sapiensENSP0000046818171.826361.9154oncorhynchus_mykissENSOMYP0000005611976.331465.7988
ENSG00000129351homo_sapiensENSP0000046818171.826361.804salmo_salarENSSSAP0000004323176.421865.7583
ENSG00000129351homo_sapiensENSP0000046818171.937661.6926salmo_salarENSSSAP0000004400376.631165.7177
ENSG00000129351homo_sapiensENSP0000046818171.937661.6926salmo_truttaENSSTUP0000009462176.631165.7177
ENSG00000129351homo_sapiensENSP0000046818169.376460.6904gadus_morhuaENSGMOP0000002988367.351358.9189
ENSG00000129351homo_sapiensENSP0000046818170.155959.9109fundulus_heteroclitusENSFHEP0000002655072.247761.6972
ENSG00000129351homo_sapiensENSP0000046818171.269560.8018poecilia_reticulataENSPREP0000002017477.575866.1818
ENSG00000129351homo_sapiensENSP0000046818171.269560.9131xiphophorus_maculatusENSXMAP0000000887977.575866.303
ENSG00000129351homo_sapiensENSP0000046818170.935461.9154oryzias_latipesENSORLP0000002051075.743266.1118
ENSG00000129351homo_sapiensENSP0000046818173.162663.8085cyclopterus_lumpusENSCLMP0000504525575.517265.8621
ENSG00000129351homo_sapiensENSP0000046818172.605863.363oreochromis_niloticusENSONIP0000006979976.886867.0991
ENSG00000129351homo_sapiensENSP0000046818172.494463.363haplochromis_burtoniENSHBUP0000001781576.768967.0991
ENSG00000129351homo_sapiensENSP0000046818172.605863.363astatotilapia_callipteraENSACLP0000000243276.886867.0991
ENSG00000129351homo_sapiensENSP0000046818173.051263.6971sparus_aurataENSSAUP0001005819476.102166.3573
ENSG00000129351homo_sapiensENSP0000046818171.158162.3608lates_calcariferENSLCAP0001003518572.86263.854
ENSG00000129351homo_sapiensENSP0000046818178.730571.0468xenopus_tropicalisENSXETP0000009728770.629463.7363
ENSG00000129351homo_sapiensENSP0000046818190.200485.8575chrysemys_picta_belliiENSCPBP0000001523393.533589.03
ENSG00000129351homo_sapiensENSP0000046818123.273921.3808sphenodon_punctatusENSSPUP0000001175687.447780.3347
ENSG00000129351homo_sapiensENSP0000046818182.962178.2851laticauda_laticaudataENSLLTP0000002018988.58583.591
ENSG00000129351homo_sapiensENSP0000046818187.639282.6281notechis_scutatusENSNSUP0000002236491.724986.4802
ENSG00000129351homo_sapiensENSP0000046818191.202786.1915pseudonaja_textilisENSPTXP0000001612791.202786.1915
ENSG00000129351homo_sapiensENSP0000046818112.026710.9131anas_platyrhynchos_platyrhynchosENSAPLP0000002250895.575286.7257
ENSG00000129351homo_sapiensENSP0000046818141.31438.9755meleagris_gallopavoENSMGAP0000002242594.884989.5141
ENSG00000129351homo_sapiensENSP0000046818179.955573.8307serinus_canariaENSSCAP0000000782578.987972.9373
ENSG00000129351homo_sapiensENSP0000046818191.648185.7461anolis_carolinensisENSACAP0000001543792.575986.6142
ENSG00000129351homo_sapiensENSP0000046818121.826316.8151neolamprologus_brichardiENSNBRP0000001301776.264658.7549
ENSG00000129351homo_sapiensENSP0000046818155.345249.2205neolamprologus_brichardiENSNBRP0000001299972.133564.1509
ENSG00000129351homo_sapiensENSP0000046818191.31486.3029naja_najaENSNNAP0000002739192.134887.0787
ENSG00000129351homo_sapiensENSP0000046818191.648186.3029podarcis_muralisENSPMRP0000003494892.161386.7861
ENSG00000129351homo_sapiensENSP0000046818176.614771.7149geospiza_fortisENSGFOP0000000731585.465880
ENSG00000129351homo_sapiensENSP0000046818192.204987.4165taeniopygia_guttataENSTGUP0000001410791.592986.8363
ENSG00000129351homo_sapiensENSP0000046818183.296277.7283taeniopygia_guttataENSTGUP0000002680181.927776.4513
ENSG00000129351homo_sapiensENSP0000046818175.389867.5947erpetoichthys_calabaricusENSECRP0000003250569.578662.3844
ENSG00000129351homo_sapiensENSP0000046818171.380861.5813kryptolebias_marmoratusENSKMAP0000001434275.234764.9061
ENSG00000129351homo_sapiensENSP0000046818192.427687.6392salvator_merianaeENSSMRP0000000578193.679588.8262
ENSG00000129351homo_sapiensENSP0000046818155.233948.6637oryzias_javanicusENSOJAP0000000100981.311571.6393
ENSG00000129351homo_sapiensENSP0000046818162.026754.6771amphilophus_citrinellusENSACIP0000002650285.038274.9618
ENSG00000129351homo_sapiensENSP0000046818159.0252.1158dicentrarchus_labraxENSDLAP0000504003270.950562.6506
ENSG00000129351homo_sapiensENSP0000046818172.828563.5857amphiprion_perculaENSAPEP0000002484076.401966.7056
ENSG00000129351homo_sapiensENSP0000046818170.824162.0267oryzias_sinensisENSOSIP0000003293575.624366.2307
ENSG00000129351homo_sapiensENSP0000046818191.31486.637pelodiscus_sinensisENSPSIP0000000909993.07688.3087
ENSG00000129351homo_sapiensENSP0000046818194.654890.2004gopherus_evgoodeiENSGEVP0000501764594.026689.6018
ENSG00000129351homo_sapiensENSP0000046818194.543490.3118chelonoidis_abingdoniiENSCABP0000000584994.124289.9113
ENSG00000129351homo_sapiensENSP0000046818173.385363.4744seriola_dumeriliENSSDUP0000001197577.07666.6667
ENSG00000129351homo_sapiensENSP0000046818167.928759.02cottoperca_gobioENSCGOP0000001096070.034460.8496
ENSG00000129351homo_sapiensENSP0000046818194.320790.2004struthio_camelus_australisENSSCUP0000000255593.281989.207
ENSG00000129351homo_sapiensENSP0000046818194.209489.6437anser_brachyrhynchusENSABRP0000002715093.584189.0487
ENSG00000129351homo_sapiensENSP0000046818146.547941.0913gasterosteus_aculeatusENSGACP0000000829589.125878.678
ENSG00000129351homo_sapiensENSP0000046818172.04961.9154cynoglossus_semilaevisENSCSEP0000002544369.719859.9138
ENSG00000129351homo_sapiensENSP0000046818163.02954.5657poecilia_formosaENSPFOP0000000106583.976372.7003
ENSG00000129351homo_sapiensENSP0000046818168.708259.9109myripristis_murdjanENSMMDP0000504832776.45666.6667
ENSG00000129351homo_sapiensENSP0000046818172.160462.9176sander_luciopercaENSSLUP0000005212476.056366.3146
ENSG00000129351homo_sapiensENSP0000046818191.425485.8575strigops_habroptilaENSSHBP0000502013687.995782.6367
ENSG00000129351homo_sapiensENSP0000046818172.939963.6971amphiprion_ocellarisENSAOCP0000000591176.518766.8224
ENSG00000129351homo_sapiensENSP0000046818194.543490.2004terrapene_carolina_triunguisENSTMTP0000003105593.812289.5028
ENSG00000129351homo_sapiensENSP0000046818172.04962.0267hucho_huchoENSHHUP0000009025776.658865.9953
ENSG00000129351homo_sapiensENSP0000046818171.714961.9154hucho_huchoENSHHUP0000005970971.081761.3687
ENSG00000129351homo_sapiensENSP0000046818172.717163.029betta_splendensENSBSLP0000000900176.463766.2763
ENSG00000129351homo_sapiensENSP0000046818173.719464.0312pygocentrus_nattereriENSPNAP0000000164377.608467.4091
ENSG00000129351homo_sapiensENSP0000046818154.231647.5501anabas_testudineusENSATEP0000001838270.784962.064
ENSG00000129351homo_sapiensENSP0000046818171.603662.9176anabas_testudineusENSATEP0000001813277.00667.6647
ENSG00000129351homo_sapiensENSP0000046818111.02457.01559ciona_savignyiENSCSAVP0000000326640.08125.5061
ENSG00000129351homo_sapiensENSP0000046818110.46777.12695ciona_savignyiENSCSAVP0000001152944.761930.4762
ENSG00000129351homo_sapiensENSP0000046818173.385363.4744seriola_lalandi_dorsalisENSSLDP0000002198977.07666.6667
ENSG00000129351homo_sapiensENSP0000046818172.717162.8062labrus_bergyltaENSLBEP0000003091875.317265.0519
ENSG00000129351homo_sapiensENSP0000046818149.554642.3163labrus_bergyltaENSLBEP0000000354068.356458.3717
ENSG00000129351homo_sapiensENSP0000046818172.605863.4744pundamilia_nyerereiENSPNYP0000000269576.796267.1378
ENSG00000129351homo_sapiensENSP0000046818172.939963.363mastacembelus_armatusENSMAMP0000001564076.608266.5497
ENSG00000129351homo_sapiensENSP0000046818172.828563.6971stegastes_partitusENSSPAP0000002414976.491266.9006
ENSG00000129351homo_sapiensENSP0000046818171.492261.3586oncorhynchus_tshawytschaENSOTSP0000502596876.066465.2844
ENSG00000129351homo_sapiensENSP0000046818171.714961.9154oncorhynchus_tshawytschaENSOTSP0000502357476.21365.7988
ENSG00000129351homo_sapiensENSP0000046818172.939963.363acanthochromis_polyacanthusENSAPOP0000000916469.0259.9579
ENSG00000129351homo_sapiensENSP0000046818190.645986.0802aquila_chrysaetos_chrysaetosENSACCP0002000270191.873687.246
ENSG00000129351homo_sapiensENSP0000046818192.093587.5278aquila_chrysaetos_chrysaetosENSACCP0002001985885.788481.5353
ENSG00000129351homo_sapiensENSP0000046818170.935461.5813nothobranchius_furzeriENSNFUP0001500623175.563565.5991
ENSG00000129351homo_sapiensENSP0000046818164.031254.8998cyprinodon_variegatusENSCVAP0000000631082.85371.0375
ENSG00000129351homo_sapiensENSP0000046818172.939963.029denticeps_clupeoidesENSDCDP0000001960476.340365.9674
ENSG00000129351homo_sapiensENSP0000046818173.273963.8085larimichthys_croceaENSLCRP0000503469076.069466.2428
ENSG00000129351homo_sapiensENSP0000046818166.035659.4655ficedula_albicollisENSFALP0000003204079.172271.2951
ENSG00000129351homo_sapiensENSP0000046818169.821859.5768hippocampus_comesENSHCOP0000001582474.731863.7664
ENSG00000129351homo_sapiensENSP0000046818171.046862.3608cyprinus_carpio_carpioENSCCRP0000000953875.77266.5083
ENSG00000129351homo_sapiensENSP0000046818171.714963.363cyprinus_carpio_carpioENSCCRP0000001477477.033568.0622
ENSG00000129351homo_sapiensENSP0000046818169.933262.5835coturnix_japonicaENSCJPP0000500502160.442754.0905
ENSG00000129351homo_sapiensENSP0000046818162.917654.4543poecilia_latipinnaENSPLAP0000002865083.827972.5519
ENSG00000129351homo_sapiensENSP0000046818168.262859.3541sinocyclocheilus_grahamiENSSGRP0000007914775.67965.8025
ENSG00000129351homo_sapiensENSP0000046818163.251754.4543sinocyclocheilus_grahamiENSSGRP0000006677171.898761.8987
ENSG00000129351homo_sapiensENSP0000046818172.605863.363maylandia_zebraENSMZEP0000500308476.977667.1783
ENSG00000129351homo_sapiensENSP0000046818153.340845.2116tetraodon_nigroviridisENSTNIP0000001115965.258955.3134
ENSG00000129351homo_sapiensENSP0000046818170.601361.3586paramormyrops_kingsleyaeENSPKIP0000002345866.041757.3958
ENSG00000129351homo_sapiensENSP0000046818119.042315.9243paramormyrops_kingsleyaeENSPKIP0000002559253.105644.4099
ENSG00000129351homo_sapiensENSP0000046818174.053563.363scleropages_formosusENSSFOP0001502316777.505866.317
ENSG00000129351homo_sapiensENSP0000046818171.603662.2494scleropages_formosusENSSFOP0001501360870.893161.6318
ENSG00000129351homo_sapiensENSP0000046818172.939965.1448leptobrachium_leishanenseENSLLEP0000000636871.428663.795
ENSG00000129351homo_sapiensENSP0000046818173.385362.5835scophthalmus_maximusENSSMAP0000000390976.450165.1972
ENSG00000129351homo_sapiensENSP0000046818170.824161.4699oryzias_melastigmaENSOMEP0000003204275.804565.7926

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001618enables virus receptor activity1IDAHomo_sapiens(9606)Function
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding2HDA,NASHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0003727enables single-stranded RNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1HDAHomo_sapiens(9606)Component
GO:0005634located_in nucleus2IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0006468involved_in protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0017148involved_in negative regulation of translation1ISSHomo_sapiens(9606)Process
GO:0035925enables mRNA 3-UTR AU-rich region binding1IDAHomo_sapiens(9606)Function
GO:0045071involved_in negative regulation of viral genome replication1ISSHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0046718involved_in viral entry into host cell1IEAHomo_sapiens(9606)Process
GO:0051607involved_in defense response to virus1IEAHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression