Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000127054 Gene ID 54973 Accession 26052
Symbol INTS11 Alias RC68;INT11;PSF3L;RC-68;CPSF3L;CPSF73L;NEDMLOB Full Name integrator complex subunit 11
Status Confidence Length 13103 bases Strand Minus strand
Position 1 : 1311585 - 1324687 RNA binding domain Lactamase_B , Beta-Casp , RMMBL
Summary The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000464436 RMMBL PF07521 5.5e-16 1
ENSP00000464436 Beta-Casp PF10996 3.5e-20 2
ENSP00000400548 RMMBL PF07521 9e-16 1
ENSP00000400548 Beta-Casp PF10996 4.7e-25 2
ENSP00000481821 RMMBL PF07521 9.1e-16 1
ENSP00000481821 Beta-Casp PF10996 4.7e-25 2
ENSP00000404886 RMMBL PF07521 9.1e-16 1
ENSP00000404886 Beta-Casp PF10996 4.6e-25 2
ENSP00000444672 RMMBL PF07521 1.1e-15 1
ENSP00000444672 Beta-Casp PF10996 4.1e-25 2
ENSP00000444672 Lactamase_B PF00753 4.8e-07 3
ENSP00000392848 RMMBL PF07521 1.1e-15 1
ENSP00000392848 Beta-Casp PF10996 4.7e-25 2
ENSP00000392848 Lactamase_B PF00753 1e-09 3
ENSP00000413493 RMMBL PF07521 1.2e-15 1
ENSP00000413493 Beta-Casp PF10996 4.8e-25 2
ENSP00000413493 Lactamase_B PF00753 1.9e-10 3
ENSP00000445001 RMMBL PF07521 1.2e-15 1
ENSP00000445001 Beta-Casp PF10996 4.9e-25 2
ENSP00000445001 Lactamase_B PF00753 2e-10 3
ENSP00000436743 Lactamase_B PF00753 1.6e-11 1
ENSP00000432777 Lactamase_B PF00753 2.2e-11 1
ENSP00000432009 Lactamase_B PF00753 2.7e-11 1
ENSP00000435772 Lactamase_B PF00753 1.1e-08 1
ENSP00000436824 Lactamase_B PF00753 1.3e-08 1
ENSP00000481275 Lactamase_B PF00753 3.7e-08 1
ENSP00000411233 Lactamase_B PF00753 5.1e-08 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36028512 BRAT1 links Integrator and defective RNA processing with neurodegeneration. Zuzana Cihlarova 2022-08-26 Nature communications
28335732 Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways. K Alexander Kheirallah 2017-03-23 BMC genomics
25410209 Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes. Bernd Stadelmayer 2014-11-20 Nature communications
32923585 Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1. Jasmine Barra 2020-07-01 Science advances
36180473 Inositol hexakisphosphate is required for Integrator function. Min-Han Lin 2022-09-30 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
INTS11-214 ENST00000470030 2369 No protein -
INTS11-247 ENST00000540437 2629 606aa ENSP00000445001
INTS11-248 ENST00000545578 2263 571aa ENSP00000444672
INTS11-249 ENST00000620829 1862 502aa ENSP00000481821
INTS11-222 ENST00000497304 932 No protein -
INTS11-201 ENST00000323275 2450 No protein -
INTS11-208 ENST00000435064 2114 600aa ENSP00000413493
INTS11-202 ENST00000411962 1832 502aa ENSP00000400548
INTS11-212 ENST00000462432 2863 No protein -
INTS11-216 ENST00000478641 3079 No protein -
INTS11-204 ENST00000421495 1868 342aa ENSP00000464436
INTS11-210 ENST00000458452 2571 62aa ENSP00000433930
INTS11-203 ENST00000419704 1798 499aa ENSP00000404886
INTS11-243 ENST00000532772 1618 46aa ENSP00000431214
INTS11-209 ENST00000450926 1839 578aa ENSP00000392848
INTS11-233 ENST00000527098 2004 92aa ENSP00000431952
INTS11-217 ENST00000485710 883 No protein -
INTS11-211 ENST00000461514 913 No protein -
INTS11-225 ENST00000525164 816 No protein -
INTS11-236 ENST00000528879 1524 278aa ENSP00000432777
INTS11-228 ENST00000525769 695 No protein -
INTS11-242 ENST00000531377 816 54aa ENSP00000433264
INTS11-234 ENST00000527383 668 No protein -
INTS11-241 ENST00000531292 704 No protein -
INTS11-213 ENST00000467408 639 No protein -
INTS11-207 ENST00000434694 1056 344aa ENSP00000411233
INTS11-240 ENST00000531020 548 No protein -
INTS11-245 ENST00000533916 405 No protein -
INTS11-218 ENST00000488042 1134 No protein -
INTS11-231 ENST00000526797 659 81aa ENSP00000435418
INTS11-230 ENST00000526332 579 109aa ENSP00000434790
INTS11-206 ENST00000430786 849 101aa ENSP00000404012
INTS11-235 ENST00000527719 750 209aa ENSP00000436743
INTS11-237 ENST00000530031 800 249aa ENSP00000432009
INTS11-229 ENST00000526113 591 No protein -
INTS11-232 ENST00000526904 551 No protein -
INTS11-227 ENST00000525603 738 No protein -
INTS11-205 ENST00000429572 1104 289aa ENSP00000481275
INTS11-223 ENST00000498173 1589 No protein -
INTS11-221 ENST00000496353 2428 No protein -
INTS11-220 ENST00000493534 896 No protein -
INTS11-246 ENST00000534345 485 140aa ENSP00000435772
INTS11-244 ENST00000532952 773 No protein -
INTS11-219 ENST00000490853 704 No protein -
INTS11-239 ENST00000531019 549 56aa ENSP00000433733
INTS11-224 ENST00000498476 554 167aa ENSP00000436824
INTS11-215 ENST00000470679 584 55aa ENSP00000434782
INTS11-226 ENST00000525285 579 64aa ENSP00000436396
INTS11-238 ENST00000530233 595 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
62138Colitis, Ulcerative1E-926192919
74638Inflammatory Bowel Diseases2E-728067908
80311Crohn Disease6E-726192919
80368Inflammatory Bowel Diseases3E-1126192919
82696Inflammatory Bowel Diseases8E-1323128233
100436Colitis, Ulcerative3E-628067908

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000127054homo_sapiensENSP0000029887531.457816.7519homo_sapiensENSP000004134934121.8333
ENSG00000127054homo_sapiensENSP0000023811250.146232.4561homo_sapiensENSP0000041349357.166737
ENSG00000127054homo_sapiensENSP0000042906533.890616.7173homo_sapiensENSP0000041349337.166718.3333

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000127054homo_sapiensENSP0000041349381.833381nomascus_leucogenysENSNLEP0000003163792.293291.3534
ENSG00000127054homo_sapiensENSP0000041349398.598.3333pan_paniscusENSPPAP0000003020197.524797.3597
ENSG00000127054homo_sapiensENSP0000041349398.666798pongo_abeliiENSPPYP0000000232997.689897.0297
ENSG00000127054homo_sapiensENSP0000041349398.598.3333pan_troglodytesENSPTRP0000008673297.524797.3597
ENSG00000127054homo_sapiensENSP0000041349398.666797.6667gorilla_gorillaENSGGOP0000004362490.93790.0154
ENSG00000127054homo_sapiensENSP0000041349394.833390.3333ornithorhynchus_anatinusENSOANP0000002059094.833390.3333
ENSG00000127054homo_sapiensENSP0000041349381.578.5sarcophilus_harrisiiENSSHAP0000000580878.617475.7235
ENSG00000127054homo_sapiensENSP0000041349390.666788notamacropus_eugeniiENSMEUP0000001064396.453993.617
ENSG00000127054homo_sapiensENSP0000041349392.666790.3333dasypus_novemcinctusENSDNOP0000001628482.492680.4154
ENSG00000127054homo_sapiensENSP000004134939896.5erinaceus_europaeusENSEEUP000000007479896.5
ENSG00000127054homo_sapiensENSP000004134937574.1667echinops_telfairiENSETEP0000000169790.361489.3574
ENSG00000127054homo_sapiensENSP0000041349398.166797.5callithrix_jacchusENSCJAP0000005996697.516696.8543
ENSG00000127054homo_sapiensENSP0000041349397.596.3333cercocebus_atysENSCATP0000000130696.059194.9097
ENSG00000127054homo_sapiensENSP0000041349396.595macaca_mulattaENSMMUP0000004068990.046788.647
ENSG00000127054homo_sapiensENSP0000041349399.166798.6667macaca_nemestrinaENSMNEP0000001195087.628987.187
ENSG00000127054homo_sapiensENSP0000041349397.596.3333papio_anubisENSPANP0000003368396.059194.9097
ENSG00000127054homo_sapiensENSP0000041349383.333382.8333mandrillus_leucophaeusENSMLEP0000004069697.087496.5049
ENSG00000127054homo_sapiensENSP0000041349384.833382.5tursiops_truncatusENSTTRP0000001614584.97582.6377
ENSG00000127054homo_sapiensENSP0000041349398.833397.8333vulpes_vulpesENSVVUP0000000553298.833397.8333
ENSG00000127054homo_sapiensENSP0000041349398.833397.1667mus_spretusMGP_SPRETEiJ_P006897998.833397.1667
ENSG00000127054homo_sapiensENSP0000041349395.333392.6667equus_asinusENSEASP0000505471875.461773.3509
ENSG00000127054homo_sapiensENSP0000041349398.833397capra_hircusENSCHIP0000002705698.998397.1619
ENSG00000127054homo_sapiensENSP0000041349397.333395.5loxodonta_africanaENSLAFP0000001883097.171495.3411
ENSG00000127054homo_sapiensENSP0000041349397.333395.8333panthera_leoENSPLOP0000002211596.528995.0413
ENSG00000127054homo_sapiensENSP000004134939997.6667ailuropoda_melanoleucaENSAMEP000000145209997.6667
ENSG00000127054homo_sapiensENSP0000041349398.833396.8333bos_indicus_hybridENSBIXP0000500823094.577492.6635
ENSG00000127054homo_sapiensENSP0000041349398.833397.5equus_caballusENSECAP0000002861170.011869.0673
ENSG00000127054homo_sapiensENSP0000041349398.666797.6667canis_lupus_familiarisENSCAFP0084503332498.666797.6667
ENSG00000127054homo_sapiensENSP0000041349397.333396panthera_pardusENSPPRP0000002887996.528995.2066
ENSG00000127054homo_sapiensENSP000004134939998marmota_marmota_marmotaENSMMMP000000229969998
ENSG00000127054homo_sapiensENSP000004134939996.8333balaenoptera_musculusENSBMSP0001000183499.165396.995
ENSG00000127054homo_sapiensENSP000004134939896.5cavia_porcellusENSCPOP0000000463496.235794.7627
ENSG00000127054homo_sapiensENSP0000041349397.833396.3333felis_catusENSFCAP0000004953896.546195.0658
ENSG00000127054homo_sapiensENSP0000041349398.833397.6667ursus_americanusENSUAMP0000001603698.833397.6667
ENSG00000127054homo_sapiensENSP0000041349397.166794.6667monodelphis_domesticaENSMODP0000000780697.166794.6667
ENSG00000127054homo_sapiensENSP0000041349398.596.5bison_bison_bisonENSBBBP0000002251298.664496.6611
ENSG00000127054homo_sapiensENSP000004134939997monodon_monocerosENSMMNP0001501658199.165397.1619
ENSG00000127054homo_sapiensENSP0000041349397.666795sus_scrofaENSSSCP0000005031783.120680.8511
ENSG00000127054homo_sapiensENSP0000041349399.166797.8333microcebus_murinusENSMICP0000003417199.166797.8333
ENSG00000127054homo_sapiensENSP0000041349398.596.6667octodon_degusENSODEP0000001318398.596.6667
ENSG00000127054homo_sapiensENSP0000041349394.666793.3333jaculus_jaculusENSJJAP0000000428897.427196.0549
ENSG00000127054homo_sapiensENSP0000041349398.833397ovis_aries_rambouilletENSOARP0002001354498.998397.1619
ENSG00000127054homo_sapiensENSP0000041349397.666796.5ursus_maritimusENSUMAP0000000230797.180896.0199
ENSG00000127054homo_sapiensENSP0000041349353.166751.8333ochotona_princepsENSOPRP0000000165981.377579.3367
ENSG00000127054homo_sapiensENSP000004134939997delphinapterus_leucasENSDLEP0000000956399.165397.1619
ENSG00000127054homo_sapiensENSP0000041349398.596.6667physeter_catodonENSPCTP0000500344198.664496.828
ENSG00000127054homo_sapiensENSP0000041349398.666797.1667mus_caroliMGP_CAROLIEiJ_P006638698.666797.1667
ENSG00000127054homo_sapiensENSP0000041349398.666797.1667mus_musculusENSMUSP0000003090198.666797.1667
ENSG00000127054homo_sapiensENSP0000041349396.833395.5dipodomys_ordiiENSDORP0000000192098.977997.615
ENSG00000127054homo_sapiensENSP0000041349394.166792.8333mustela_putorius_furoENSMPUP0000001420398.949297.5482
ENSG00000127054homo_sapiensENSP0000041349397.166796.3333aotus_nancymaaeENSANAP0000003330495.888295.0658
ENSG00000127054homo_sapiensENSP0000041349397.596.1667saimiri_boliviensis_boliviensisENSSBOP0000000449696.217194.9013
ENSG00000127054homo_sapiensENSP0000041349352.666752vicugna_pacosENSVPAP0000000476267.521466.6667
ENSG00000127054homo_sapiensENSP0000041349399.666799.1667chlorocebus_sabaeusENSCSAP0000001732599.666799.1667
ENSG00000127054homo_sapiensENSP0000041349388.166787tupaia_belangeriENSTBEP0000000462999.249597.9362
ENSG00000127054homo_sapiensENSP0000041349398.833397.1667mesocricetus_auratusENSMAUP0000000890898.833397.1667
ENSG00000127054homo_sapiensENSP000004134939997phocoena_sinusENSPSNP0000000119795.498493.5691
ENSG00000127054homo_sapiensENSP000004134935855.8333camelus_dromedariusENSCDRP0000500858994.565291.0326
ENSG00000127054homo_sapiensENSP000004134939492.8333carlito_syrichtaENSTSYP000000268749492.8333
ENSG00000127054homo_sapiensENSP0000041349397.333396panthera_tigris_altaicaENSPTIP0000002346296.528995.2066
ENSG00000127054homo_sapiensENSP0000041349398.666797rattus_norvegicusENSRNOP0000002672598.502596.8386
ENSG00000127054homo_sapiensENSP0000041349399.166798prolemur_simusENSPSMP0000001842499.166798
ENSG00000127054homo_sapiensENSP0000041349398.666797.1667microtus_ochrogasterENSMOCP0000002509198.666797.1667
ENSG00000127054homo_sapiensENSP0000041349398.597peromyscus_maniculatus_bairdiiENSPEMP0000002064598.597
ENSG00000127054homo_sapiensENSP0000041349398.833396.6667bos_mutusENSBMUP0000003264089.57787.6133
ENSG00000127054homo_sapiensENSP0000041349398.666797.1667mus_spicilegusENSMSIP0000001788776.485875.323
ENSG00000127054homo_sapiensENSP0000041349398.666797cricetulus_griseus_chok1gshdENSCGRP0000101196898.666797
ENSG00000127054homo_sapiensENSP000004134939997.3333pteropus_vampyrusENSPVAP0000000096298.835397.1714
ENSG00000127054homo_sapiensENSP0000041349397.166794.1667vombatus_ursinusENSVURP0001003086697.166794.1667
ENSG00000127054homo_sapiensENSP0000041349385.833383rhinolophus_ferrumequinumENSRFEP0001001603571.329668.9751
ENSG00000127054homo_sapiensENSP0000041349399.166798neovison_visonENSNVIP0000000851399.166798
ENSG00000127054homo_sapiensENSP0000041349398.333396.1667bos_taurusENSBTAP0000005831483.098681.2676
ENSG00000127054homo_sapiensENSP0000041349398.333397.5heterocephalus_glaber_femaleENSHGLP0000002463284.892184.1727
ENSG00000127054homo_sapiensENSP0000041349398.833398rhinopithecus_bietiENSRBIP0000003130488.507587.7612
ENSG00000127054homo_sapiensENSP0000041349398.597.5canis_lupus_dingoENSCAFP0002001429798.597.5
ENSG00000127054homo_sapiensENSP000004134939997.8333sciurus_vulgarisENSSVLP000050000299997.8333
ENSG00000127054homo_sapiensENSP000004134939794.1667phascolarctos_cinereusENSPCIP000000095619794.1667
ENSG00000127054homo_sapiensENSP0000041349353.833349.3333phascolarctos_cinereusENSPCIP0000003119888.493181.0959
ENSG00000127054homo_sapiensENSP0000041349368.333366.3333procavia_capensisENSPCAP0000000218168.219666.223
ENSG00000127054homo_sapiensENSP000004134939896.3333nannospalax_galiliENSNGAP0000000683797.674496.0133
ENSG00000127054homo_sapiensENSP0000041349396.166793.8333bos_grunniensENSBGRP0000002163979.806477.87
ENSG00000127054homo_sapiensENSP000004134939897chinchilla_lanigeraENSCLAP0000000650797.35196.3576
ENSG00000127054homo_sapiensENSP000004134939794.8333cervus_hanglu_yarkandensisENSCHYP0000002562679.508277.7322
ENSG00000127054homo_sapiensENSP0000041349398.333396catagonus_wagneriENSCWAP0000001604798.497596.1603
ENSG00000127054homo_sapiensENSP0000041349398.333397ictidomys_tridecemlineatusENSSTOP0000001893198.169796.8386
ENSG00000127054homo_sapiensENSP000004134939997.1667otolemur_garnettiiENSOGAP0000000041798.835397.005
ENSG00000127054homo_sapiensENSP0000041349398.333397.5cebus_imitatorENSCCAP0000001756297.359796.5347
ENSG00000127054homo_sapiensENSP000004134939998urocitellus_parryiiENSUPAP000100205359998
ENSG00000127054homo_sapiensENSP0000041349398.833396.8333moschus_moschiferusENSMMSP0000001402898.998396.995
ENSG00000127054homo_sapiensENSP0000041349355.833355rhinopithecus_roxellanaENSRROP0000003193298.529497.0588
ENSG00000127054homo_sapiensENSP0000041349398.666797mus_pahariMGP_PahariEiJ_P008148998.666797
ENSG00000127054homo_sapiensENSP0000041349399.166797.6667propithecus_coquereliENSPCOP0000001080499.166797.6667
ENSG00000127054homo_sapiensENSP000004134937357.3333caenorhabditis_elegansF10B5.8.172.039556.5789
ENSG00000127054homo_sapiensENSP0000041349381.166767.8333drosophila_melanogasterFBpp008484281.574568.1742
ENSG00000127054homo_sapiensENSP0000041349382.333368ciona_intestinalisENSCINP0000000487781.652967.438
ENSG00000127054homo_sapiensENSP0000041349328.527petromyzon_marinusENSPMAP0000000640497.159192.0455
ENSG00000127054homo_sapiensENSP000004134938980.6667eptatretus_burgeriENSEBUP0000000456785.167577.193
ENSG00000127054homo_sapiensENSP0000041349389.833381.8333callorhinchus_miliiENSCMIP0000000687374.757368.0999
ENSG00000127054homo_sapiensENSP000004134938271.3333latimeria_chalumnaeENSLACP0000002139981.727671.0963
ENSG00000127054homo_sapiensENSP0000041349388.166779.6667lepisosteus_oculatusENSLOCP0000000255687.293778.8779
ENSG00000127054homo_sapiensENSP0000041349392.166783clupea_harengusENSCHAP0000006174988.621879.8077
ENSG00000127054homo_sapiensENSP0000041349392.584danio_rerioENSDARP0000003284392.809484.2809
ENSG00000127054homo_sapiensENSP0000041349339.333336.6667carassius_auratusENSCARP0000012691393.650887.3016
ENSG00000127054homo_sapiensENSP0000041349390.666781.5carassius_auratusENSCARP0000010215789.917480.8264
ENSG00000127054homo_sapiensENSP0000041349388.666780.1667carassius_auratusENSCARP0000001413586.504178.2114
ENSG00000127054homo_sapiensENSP0000041349392.584.5astyanax_mexicanusENSAMXP0000003537192.584.5
ENSG00000127054homo_sapiensENSP000004134939282.8333ictalurus_punctatusENSIPUP0000003389691.542382.4212
ENSG00000127054homo_sapiensENSP0000041349391.833382.6667esox_luciusENSELUP0000002830687.599478.8553
ENSG00000127054homo_sapiensENSP0000041349392.333384electrophorus_electricusENSEEEP0000000327190.819782.6229
ENSG00000127054homo_sapiensENSP0000041349336.166728.6667oncorhynchus_kisutchENSOKIP0000503200263.636450.4399
ENSG00000127054homo_sapiensENSP000004134939283.5oncorhynchus_kisutchENSOKIP0000506089083.509875.7943
ENSG00000127054homo_sapiensENSP000004134939283.3333oncorhynchus_mykissENSOMYP0000013515883.007575.188
ENSG00000127054homo_sapiensENSP0000041349389.666781salmo_salarENSSSAP0000009935784.194176.0563
ENSG00000127054homo_sapiensENSP0000041349349.666742.8333salmo_salarENSSSAP0000009625379.045168.1698
ENSG00000127054homo_sapiensENSP0000041349390.333381.5salmo_truttaENSSTUP0000007975881.016473.0942
ENSG00000127054homo_sapiensENSP0000041349348.166741.1667salmo_truttaENSSTUP0000004270775.064964.1558
ENSG00000127054homo_sapiensENSP0000041349390.166781.8333gadus_morhuaENSGMOP0000000716088.254580.0979
ENSG00000127054homo_sapiensENSP0000041349392.333384fundulus_heteroclitusENSFHEP0000000675292.642184.2809
ENSG00000127054homo_sapiensENSP000004134939283.1667poecilia_reticulataENSPREP0000003177192.307783.4448
ENSG00000127054homo_sapiensENSP0000041349391.833383xiphophorus_maculatusENSXMAP0000001248592.140583.2776
ENSG00000127054homo_sapiensENSP0000041349391.333381.8333oryzias_latipesENSORLP0000003073890.578581.157
ENSG00000127054homo_sapiensENSP0000041349391.833382.8333cyclopterus_lumpusENSCLMP0000500694291.680582.6955
ENSG00000127054homo_sapiensENSP000004134939081.5oreochromis_niloticusENSONIP0000005076188.524680.1639
ENSG00000127054homo_sapiensENSP0000041349390.333381.3333haplochromis_burtoniENSHBUP0000002502487.560678.8368
ENSG00000127054homo_sapiensENSP0000041349390.333381.1667astatotilapia_callipteraENSACLP0000002773187.560678.6753
ENSG00000127054homo_sapiensENSP000004134939283.1667sparus_aurataENSSAUP0001000137991.846983.0283
ENSG00000127054homo_sapiensENSP0000041349391.582.1667lates_calcariferENSLCAP0001005248286.729977.8831
ENSG00000127054homo_sapiensENSP0000041349394.833389.5xenopus_tropicalisENSXETP0000005835694.833389.5
ENSG00000127054homo_sapiensENSP0000041349383.166779chrysemys_picta_belliiENSCPBP0000003262695.047690.2857
ENSG00000127054homo_sapiensENSP0000041349394.666790sphenodon_punctatusENSSPUP0000002190594.666790
ENSG00000127054homo_sapiensENSP0000041349395.166791.1667crocodylus_porosusENSCPRP0000500096595.166791.1667
ENSG00000127054homo_sapiensENSP000004134939387.6667laticauda_laticaudataENSLLTP000000061959387.6667
ENSG00000127054homo_sapiensENSP000004134939286.1667notechis_scutatusENSNSUP0000000168891.846986.0233
ENSG00000127054homo_sapiensENSP000004134939387.5pseudonaja_textilisENSPTXP000000155659387.5
ENSG00000127054homo_sapiensENSP0000041349395.833391.8333anas_platyrhynchos_platyrhynchosENSAPLP0000000485895.833391.8333
ENSG00000127054homo_sapiensENSP0000041349394.333390.1667gallus_gallusENSGALP0001002594594.648890.4682
ENSG00000127054homo_sapiensENSP000004134939490meleagris_gallopavoENSMGAP0000000254191.262187.3786
ENSG00000127054homo_sapiensENSP0000041349395.166790.8333serinus_canariaENSSCAP0000002414595.166790.8333
ENSG00000127054homo_sapiensENSP0000041349395.333390.6667parus_majorENSPMJP0000001886095.333390.6667
ENSG00000127054homo_sapiensENSP0000041349392.166785.8333anolis_carolinensisENSACAP0000003126091.40585.124
ENSG00000127054homo_sapiensENSP0000041349385.166777neolamprologus_brichardiENSNBRP0000000323691.2582.5
ENSG00000127054homo_sapiensENSP000004134939286.3333naja_najaENSNNAP0000001696787.61982.2222
ENSG00000127054homo_sapiensENSP000004134938376.1667podarcis_muralisENSPMRP0000002174175.340469.1377
ENSG00000127054homo_sapiensENSP0000041349395.166790.6667geospiza_fortisENSGFOP0000001502495.166790.6667
ENSG00000127054homo_sapiensENSP0000041349394.589.5taeniopygia_guttataENSTGUP0000001545386.170281.6109
ENSG00000127054homo_sapiensENSP0000041349387.833380.5erpetoichthys_calabaricusENSECRP0000001513787.396480.0995
ENSG00000127054homo_sapiensENSP0000041349391.666782.5kryptolebias_marmoratusENSKMAP0000000442791.514182.3627
ENSG00000127054homo_sapiensENSP000004134939386.5salvator_merianaeENSSMRP0000001161084.545578.6364
ENSG00000127054homo_sapiensENSP0000041349391.582.5oryzias_javanicusENSOJAP0000002333982.930574.7734
ENSG00000127054homo_sapiensENSP0000041349392.166783.5amphilophus_citrinellusENSACIP0000002156592.013383.3611
ENSG00000127054homo_sapiensENSP0000041349392.583.6667dicentrarchus_labraxENSDLAP0000508135492.346183.5275
ENSG00000127054homo_sapiensENSP0000041349391.833383.5amphiprion_perculaENSAPEP0000003482991.680583.3611
ENSG00000127054homo_sapiensENSP0000041349388.333379.8333oryzias_sinensisENSOSIP0000003134782.683374.727
ENSG00000127054homo_sapiensENSP000004134939590.8333pelodiscus_sinensisENSPSIP000000029199590.8333
ENSG00000127054homo_sapiensENSP0000041349395.166791gopherus_evgoodeiENSGEVP0000501969895.166791
ENSG00000127054homo_sapiensENSP0000041349395.166791chelonoidis_abingdoniiENSCABP0000000010495.166791
ENSG00000127054homo_sapiensENSP0000041349392.166783.1667seriola_dumeriliENSSDUP0000000541992.013383.0283
ENSG00000127054homo_sapiensENSP000004134939691.3333struthio_camelus_australisENSSCUP0000001031595.681191.0299
ENSG00000127054homo_sapiensENSP0000041349395.666791.6667anser_brachyrhynchusENSABRP0000000770195.666791.6667
ENSG00000127054homo_sapiensENSP0000041349392.166783.1667gasterosteus_aculeatusENSGACP0000001490891.708182.7529
ENSG00000127054homo_sapiensENSP0000041349391.833383cynoglossus_semilaevisENSCSEP0000002720591.680582.8619
ENSG00000127054homo_sapiensENSP0000041349392.166783.3333poecilia_formosaENSPFOP0000000865892.320583.4725
ENSG00000127054homo_sapiensENSP0000041349389.166780.5myripristis_murdjanENSMMDP0000500971282.945774.8837
ENSG00000127054homo_sapiensENSP0000041349390.666781.1667sander_luciopercaENSSLUP0000002633888.455379.187
ENSG00000127054homo_sapiensENSP0000041349395.666791.5strigops_habroptilaENSSHBP0000502182195.666791.5
ENSG00000127054homo_sapiensENSP0000041349391.833383.5amphiprion_ocellarisENSAOCP0000001622191.680583.3611
ENSG00000127054homo_sapiensENSP0000041349395.166791terrapene_carolina_triunguisENSTMTP0000003159995.166791
ENSG00000127054homo_sapiensENSP0000041349341.534.6667hucho_huchoENSHHUP0000005276579.047666.0317
ENSG00000127054homo_sapiensENSP0000041349392.583.8333hucho_huchoENSHHUP0000008947392.039883.4163
ENSG00000127054homo_sapiensENSP0000041349391.583.5betta_splendensENSBSLP0000003906788.978981.1993
ENSG00000127054homo_sapiensENSP0000041349392.333384.8333pygocentrus_nattereriENSPNAP0000003348892.333384.8333
ENSG00000127054homo_sapiensENSP0000041349337.833321.3333pygocentrus_nattereriENSPNAP0000000937143.486624.5211
ENSG00000127054homo_sapiensENSP0000041349342.666723.6667pygocentrus_nattereriENSPNAP0000001082236.676220.3438
ENSG00000127054homo_sapiensENSP000004134938980.3333anabas_testudineusENSATEP0000005998986.12977.7419
ENSG00000127054homo_sapiensENSP0000041349381.833368.5ciona_savignyiENSCSAVP0000001245480.228867.1569
ENSG00000127054homo_sapiensENSP0000041349392.166783.1667seriola_lalandi_dorsalisENSSLDP0000002207292.013383.0283
ENSG00000127054homo_sapiensENSP0000041349388.833380.5labrus_bergyltaENSLBEP0000001466190.186181.7259
ENSG00000127054homo_sapiensENSP000004134939283.3333pundamilia_nyerereiENSPNYP0000002821591.846983.1947
ENSG00000127054homo_sapiensENSP0000041349388.666780.6667mastacembelus_armatusENSMAMP0000005470485.1277.44
ENSG00000127054homo_sapiensENSP0000041349391.833383.1667stegastes_partitusENSSPAP0000002424091.680583.0283
ENSG00000127054homo_sapiensENSP0000041349339.530.3333oncorhynchus_tshawytschaENSOTSP0000501733158.955245.2736
ENSG00000127054homo_sapiensENSP000004134939283.5oncorhynchus_tshawytschaENSOTSP0000501817783.007575.3383
ENSG00000127054homo_sapiensENSP0000041349391.833383.3333acanthochromis_polyacanthusENSAPOP0000001921291.680583.1947
ENSG00000127054homo_sapiensENSP0000041349395.666791.3333aquila_chrysaetos_chrysaetosENSACCP0002001786395.666791.3333
ENSG00000127054homo_sapiensENSP0000041349390.333381.8333nothobranchius_furzeriENSNFUP0001501392386.581578.4345
ENSG00000127054homo_sapiensENSP0000041349388.166779.5cyprinodon_variegatusENSCVAP000000071229282.9565
ENSG00000127054homo_sapiensENSP0000041349391.666782denticeps_clupeoidesENSDCDP0000004913491.514181.8636
ENSG00000127054homo_sapiensENSP0000041349389.666780.1667larimichthys_croceaENSLCRP0000500267583.15374.3431
ENSG00000127054homo_sapiensENSP0000041349353.833350.8333takifugu_rubripesENSTRUP0000001327694.444489.1813
ENSG00000127054homo_sapiensENSP0000041349391.833387.3333ficedula_albicollisENSFALP0000001965487.599483.3068
ENSG00000127054homo_sapiensENSP000004134939282.6667hippocampus_comesENSHCOP000000104709282.6667
ENSG00000127054homo_sapiensENSP000004134939282.3333cyprinus_carpio_carpioENSCCRP0000005539285.847676.8274
ENSG00000127054homo_sapiensENSP0000041349391.333382.5cyprinus_carpio_carpioENSCCRP0000005521290.42981.6832
ENSG00000127054homo_sapiensENSP0000041349395.833392coturnix_japonicaENSCJPP0000501187995.833392
ENSG00000127054homo_sapiensENSP000004134939283.1667poecilia_latipinnaENSPLAP0000002921392.307783.4448
ENSG00000127054homo_sapiensENSP0000041349391.333382.5sinocyclocheilus_grahamiENSSGRP0000005139090.280181.5486
ENSG00000127054homo_sapiensENSP000004134939283.1667maylandia_zebraENSMZEP0000503133491.846983.0283
ENSG00000127054homo_sapiensENSP0000041349391.583.5tetraodon_nigroviridisENSTNIP0000001538591.347883.3611
ENSG00000127054homo_sapiensENSP0000041349392.333385paramormyrops_kingsleyaeENSPKIP0000002512692.179784.8586
ENSG00000127054homo_sapiensENSP0000041349389.333382.1667scleropages_formosusENSSFOP0001506329286.731479.7735
ENSG00000127054homo_sapiensENSP0000041349388.666781.3333leptobrachium_leishanenseENSLLEP0000003554584.848577.8309
ENSG00000127054homo_sapiensENSP0000041349385.666775.1667scophthalmus_maximusENSSMAP0000005364781.072671.1356
ENSG00000127054homo_sapiensENSP0000041349391.333382oryzias_melastigmaENSOMEP0000001648492.255982.8283

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004521enables RNA endonuclease activity2IBA,IMPHomo_sapiens(9606)Function
GO:0005515contributes_to protein binding2IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0016180involved_in snRNA processing3IBA,IDA,NASHomo_sapiens(9606)Process
GO:0032039part_of integrator complex2IDA,NASHomo_sapiens(9606)Component
GO:0034243involved_in regulation of transcription elongation by RNA polymerase II1NASHomo_sapiens(9606)Process
GO:0072562located_in blood microparticle1HDAHomo_sapiens(9606)Component

Expression