Ensembl ID ENSG00000127054 Gene ID 54973 Accession 26052
Gene Symbol INTS11 Alias RC68;INT11;PSF3L;RC-68;CPSF3L;CPSF73L;NEDMLOB Full Name integrator complex subunit 11
Position 1 : 1311585 - 1324687 Length 13103 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

ENSG00000127054 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000127054 INTS11 0.53 1.68e-17 KIRC
ENSG00000127054 INTS11 0.35 4.87e-11 BRCA
ENSG00000127054 INTS11 0.47 1.60e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000127054 INTS11 pancreatic cancer 30635821
ENSG00000127054 INTS11 tumor 31037333
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000127054 INTS11 MESO 0.00033 low
ENSG00000127054 INTS11 SARC 0.00062 high
ENSG00000127054 INTS11 CHOL 0.02 low
ENSG00000127054 INTS11 PAAD 0.012 low
ENSG00000127054 INTS11 THCA 0.041 low
ENSG00000127054 INTS11 ACC 0.00011 high
ENSG00000127054 INTS11 LGG 0.0011 high
ENSG00000127054 INTS11 LUSC 0.019 high
ENSG00000127054 INTS11 KIRP 0.0017 low
ENSG00000127054 INTS11 KICH 0.0014 high
ENSG00000127054 INTS11 LUAD 0.017 low
ENSG00000127054 INTS11 THYM 0.014 low
ENSG00000127054 INTS11 COAD 0.024 high
ENSG00000127054 INTS11 OV 0.025 high
ENSG00000127054 INTS11 TGCT 0.0032 high
ENSG00000127054 INTS11 BLCA 0.00017 low
ENSG00000127054 INTS11 GBM 0.041 low
ENSG00000127054 INTS11 CESC 0.0019 low
ENSG00000127054 INTS11 LIHC 0.00063 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency