RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2DengueZika
Drug	N.A.
Main interacting RNAs	tRNA
Moonlighting functions	N.A.
Localizations	Stress granucleNucleoli
BulkPerturb-seq	DataSet_01_418 DataSet_01_63

Ensembl ID	ENSG00000125977	Gene ID	8894	Accession	3266
Symbol	EIF2S2	Alias	EIF2;EIF2B;PPP1R67;EIF2beta;eIF-2-beta	Full Name	eukaryotic translation initiation factor 2 subunit beta
Status	Confidence	Length	23935 bases	Strand	Minus strand
Position	20 : 34088309 - 34112243	RNA binding domain	eIF-5_eIF-2B
Summary	Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]