RBP Type
Canonical_RBPs
Diseases
Cancer
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000124795 Gene ID
7913
Accession
2768
Symbol
DEK
Alias
D6S231E
Full Name
DEK proto-oncogene
Status
Confidence
Length
40689 bases
Strand
Minus strand
Position
6 : 18223860 - 18264548
RNA binding domain
SAP
Summary
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000425399
SAP
PF02037
5.2e-06
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
30412857
The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival.
E Kari Hacker
2018-12-01
Neoplasia (New York, N.Y.)
25945971
DEK over-expression promotes mitotic defects and micronucleus formation.
C Marie Matrka
2015-01-01
Cell cycle (Georgetown, Tex.)
20501624
Control of tumorigenesis and chemoresistance by the DEK oncogene.
Erica Riveiro-Falkenbach
2010-06-01
Clinical cancer research : an official journal of the American Association for Cancer Research
35475534
DEK modulates both expression and alternative splicing of cancer‑related genes.
Bin Liu
2022-06-01
Oncology reports
33755722
Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis.
Zhe Chen
2021-05-03
The Journal of experimental medicine
23733396
Concise review: role of DEK in stem/progenitor cell biology.
E Hal Broxmeyer
2013-08-01
Stem cells (Dayton, Ohio)
33689684
A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.
Rakesh Chatrikhi
2021-08-19
Cell chemical biology
25326705
Mechanisms for U2AF to define 3' splice sites and regulate alternative splicing in the human genome.
Changwei Shao
2014-11-01
Nature structural & molecular biology
30861322
Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis.
A Ray Ohara
2019-08-01
Arthritis & rheumatology (Hoboken, N.J.)
25216995
The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.
Carl Sandén
2014-09-12
Molecular cancer
18332104
DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress.
F Kappes
2008-05-01
Molecular and cellular biology
36288392
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.
Claudia Chiriches
2022-10-01
PLoS genetics
26425120
Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer.
A Nicholas Pease
2015-01-01
Journal of oncology
10908574
The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes.
T McGarvey
2000-07-24
The Journal of cell biology
Name
Transcript ID
bp
Protein
Translation ID
DEK-212
ENST00000652689
3142
375aa
ENSP00000498653
DEK-210
ENST00000652292
3954
No protein
-
DEK-208
ENST00000651624
2587
303aa
ENSP00000498930
DEK-209
ENST00000651992
2851
380aa
ENSP00000498320
DEK-207
ENST00000515770
2895
285aa
ENSP00000422380
DEK-204
ENST00000507591
3093
380aa
ENSP00000423427
DEK-203
ENST00000505224
1372
347aa
ENSP00000421165
DEK-201
ENST00000244776
1441
341aa
ENSP00000244776
DEK-211
ENST00000652576
1360
375aa
ENSP00000498335
DEK-205
ENST00000512145
791
No protein
-
DEK-202
ENST00000503715
580
122aa
ENSP00000425399
DEK-206
ENST00000515742
1906
162aa
ENSP00000423553
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
93584 thiopurine methyltransferase 5E-34 27770449
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000124795
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000124795 homo_sapiens ENSP00000498653 99.2 98.4 pan_paniscus ENSPPAP00000012390 98.153 97.3615 ENSG00000124795 homo_sapiens ENSP00000498653 99.7333 99.4667 pan_troglodytes ENSPTRP00000030325 100 99.7326 ENSG00000124795 homo_sapiens ENSP00000498653 99.7333 99.7333 gorilla_gorilla ENSGGOP00000012535 99.7333 99.7333 ENSG00000124795 homo_sapiens ENSP00000498653 92.2667 85.6 ornithorhynchus_anatinus ENSOANP00000018773 91.2929 84.6966 ENSG00000124795 homo_sapiens ENSP00000498653 93.6 87.7333 sarcophilus_harrisii ENSSHAP00000017264 93.8503 87.9679 ENSG00000124795 homo_sapiens ENSP00000498653 43.2 37.8667 notamacropus_eugenii ENSMEUP00000007933 53.2895 46.7105 ENSG00000124795 homo_sapiens ENSP00000498653 86.6667 83.7333 choloepus_hoffmanni ENSCHOP00000004759 77.7512 75.1196 ENSG00000124795 homo_sapiens ENSP00000498653 83.2 78.6667 dasypus_novemcinctus ENSDNOP00000029602 91.7647 86.7647 ENSG00000124795 homo_sapiens ENSP00000498653 95.7333 92.2667 erinaceus_europaeus ENSEEUP00000001473 95.7333 92.2667 ENSG00000124795 homo_sapiens ENSP00000498653 50.6667 47.4667 echinops_telfairi ENSETEP00000014776 61.0932 57.2347 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 97.6 callithrix_jacchus ENSCJAP00000088834 90.4177 89.9263 ENSG00000124795 homo_sapiens ENSP00000498653 80.5333 78.9333 cercocebus_atys ENSCATP00000015922 99.3421 97.3684 ENSG00000124795 homo_sapiens ENSP00000498653 79.2 76.5333 cercocebus_atys ENSCATP00000012238 91.1043 88.0368 ENSG00000124795 homo_sapiens ENSP00000498653 99.4667 98.9333 macaca_fascicularis ENSMFAP00000023226 99.4667 98.9333 ENSG00000124795 homo_sapiens ENSP00000498653 99.4667 98.9333 macaca_mulatta ENSMMUP00000057509 99.4667 98.9333 ENSG00000124795 homo_sapiens ENSP00000498653 51.7333 51.7333 macaca_nemestrina ENSMNEP00000029281 95.5665 95.5665 ENSG00000124795 homo_sapiens ENSP00000498653 83.2 80.5333 macaca_nemestrina ENSMNEP00000029141 92.5816 89.6142 ENSG00000124795 homo_sapiens ENSP00000498653 90.9333 89.8667 macaca_nemestrina ENSMNEP00000032732 97.151 96.0114 ENSG00000124795 homo_sapiens ENSP00000498653 99.4667 98.6667 macaca_nemestrina ENSMNEP00000040464 99.2021 98.4043 ENSG00000124795 homo_sapiens ENSP00000498653 67.4667 64.8 papio_anubis ENSPANP00000017121 92 88.3636 ENSG00000124795 homo_sapiens ENSP00000498653 99.4667 98.9333 papio_anubis ENSPANP00000013722 98.1579 97.6316 ENSG00000124795 homo_sapiens ENSP00000498653 76.5333 76 papio_anubis ENSPANP00000046895 97.9522 97.2696 ENSG00000124795 homo_sapiens ENSP00000498653 98.9333 97.8667 mandrillus_leucophaeus ENSMLEP00000012351 97.6316 96.5789 ENSG00000124795 homo_sapiens ENSP00000498653 45.8667 45.0667 mandrillus_leucophaeus ENSMLEP00000022144 97.7273 96.0227 ENSG00000124795 homo_sapiens ENSP00000498653 39.7333 39.2 mandrillus_leucophaeus ENSMLEP00000033681 93.125 91.875 ENSG00000124795 homo_sapiens ENSP00000498653 89.0667 86.4 tursiops_truncatus ENSTTRP00000006762 78.9598 76.5957 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 92.5333 vulpes_vulpes ENSVVUP00000003792 90.7731 86.5337 ENSG00000124795 homo_sapiens ENSP00000498653 95.4667 90.6667 mus_spretus MGP_SPRETEiJ_P0035880 94.2105 89.4737 ENSG00000124795 homo_sapiens ENSP00000498653 96.5333 93.3333 equus_asinus ENSEASP00005060311 94.517 91.3838 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 93.0667 capra_hircus ENSCHIP00000033011 96.2963 92.328 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 92.5333 loxodonta_africana ENSLAFP00000022430 96.8085 92.2872 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 94.9333 panthera_leo ENSPLOP00000030802 96.3351 93.1937 ENSG00000124795 homo_sapiens ENSP00000498653 94.9333 89.6 ailuropoda_melanoleuca ENSAMEP00000025213 78.4141 74.0088 ENSG00000124795 homo_sapiens ENSP00000498653 96.8 92.8 bos_indicus_hybrid ENSBIXP00005003415 96.8 92.8 ENSG00000124795 homo_sapiens ENSP00000498653 96.5333 92.5333 oryctolagus_cuniculus ENSOCUP00000019290 95.2632 91.3158 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 93.8667 equus_caballus ENSECAP00000083441 93.5897 90.2564 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 93.6 canis_lupus_familiaris ENSCAFP00845040125 96.817 93.1034 ENSG00000124795 homo_sapiens ENSP00000498653 97.6 93.3333 canis_lupus_familiaris ENSCAFP00845003041 96.8254 92.5926 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 94.9333 panthera_pardus ENSPPRP00000016508 97.6127 94.4297 ENSG00000124795 homo_sapiens ENSP00000498653 47.2 44.8 marmota_marmota_marmota ENSMMMP00000018341 90.7692 86.1538 ENSG00000124795 homo_sapiens ENSP00000498653 97.8667 94.6667 balaenoptera_musculus ENSBMSP00010012677 97.8667 94.6667 ENSG00000124795 homo_sapiens ENSP00000498653 96.8 93.3333 cavia_porcellus ENSCPOP00000032381 97.0588 93.5829 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 95.2 felis_catus ENSFCAP00000035434 97.6127 94.695 ENSG00000124795 homo_sapiens ENSP00000498653 87.7333 84 ursus_americanus ENSUAMP00000036861 93.7322 89.7436 ENSG00000124795 homo_sapiens ENSP00000498653 93.6 88 monodelphis_domestica ENSMODP00000014130 94.3548 88.7097 ENSG00000124795 homo_sapiens ENSP00000498653 83.7333 73.6 monodelphis_domestica ENSMODP00000020398 58.1481 51.1111 ENSG00000124795 homo_sapiens ENSP00000498653 96.8 92.5333 bison_bison_bison ENSBBBP00000018625 96.8 92.5333 ENSG00000124795 homo_sapiens ENSP00000498653 97.8667 94.4 monodon_monoceros ENSMMNP00015017955 97.8667 94.4 ENSG00000124795 homo_sapiens ENSP00000498653 41.3333 38.6667 sus_scrofa ENSSSCP00000080900 87.0787 81.4607 ENSG00000124795 homo_sapiens ENSP00000498653 97.8667 94.1333 sus_scrofa ENSSSCP00000061829 95.8225 92.1671 ENSG00000124795 homo_sapiens ENSP00000498653 98.9333 96.8 microcebus_murinus ENSMICP00000039672 98.6702 96.5426 ENSG00000124795 homo_sapiens ENSP00000498653 91.7333 87.4667 octodon_degus ENSODEP00000007353 93.4783 89.1304 ENSG00000124795 homo_sapiens ENSP00000498653 95.4667 89.0667 jaculus_jaculus ENSJJAP00000003688 93.2292 86.9792 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 93.0667 ovis_aries_rambouillet ENSOARP00020016362 96.5517 92.5729 ENSG00000124795 homo_sapiens ENSP00000498653 97.6 94.1333 ursus_maritimus ENSUMAP00000022583 94.3299 90.9794 ENSG00000124795 homo_sapiens ENSP00000498653 62.6667 59.2 ochotona_princeps ENSOPRP00000006108 59.3434 56.0606 ENSG00000124795 homo_sapiens ENSP00000498653 97.8667 94.4 delphinapterus_leucas ENSDLEP00000000994 97.8667 94.4 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 93.3333 physeter_catodon ENSPCTP00005024334 96.0526 92.1053 ENSG00000124795 homo_sapiens ENSP00000498653 95.2 90.9333 mus_caroli MGP_CAROLIEiJ_P0034257 93.9474 89.7368 ENSG00000124795 homo_sapiens ENSP00000498653 95.4667 90.9333 mus_musculus ENSMUSP00000021807 94.2105 89.7368 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 94.1333 dipodomys_ordii ENSDORP00000020913 96.3061 93.1398 ENSG00000124795 homo_sapiens ENSP00000498653 86.1333 80 mustela_putorius_furo ENSMPUP00000004992 87.5339 81.3008 ENSG00000124795 homo_sapiens ENSP00000498653 97.6 97.3333 aotus_nancymaae ENSANAP00000028477 95.8115 95.5497 ENSG00000124795 homo_sapiens ENSP00000498653 98.6667 98.1333 saimiri_boliviensis_boliviensis ENSSBOP00000007853 98.4043 97.8723 ENSG00000124795 homo_sapiens ENSP00000498653 86.1333 84.2667 vicugna_pacos ENSVPAP00000001918 99.0798 96.9325 ENSG00000124795 homo_sapiens ENSP00000498653 92.2667 90.4 chlorocebus_sabaeus ENSCSAP00000004987 95.8449 93.9058 ENSG00000124795 homo_sapiens ENSP00000498653 76.5333 74.9333 tupaia_belangeri ENSTBEP00000007760 76.5333 74.9333 ENSG00000124795 homo_sapiens ENSP00000498653 95.7333 90.6667 mesocricetus_auratus ENSMAUP00000005803 90.8861 86.076 ENSG00000124795 homo_sapiens ENSP00000498653 97.6 94.1333 phocoena_sinus ENSPSNP00000011947 97.6 94.1333 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 94.9333 camelus_dromedarius ENSCDRP00005026397 97.6127 94.4297 ENSG00000124795 homo_sapiens ENSP00000498653 95.4667 93.8667 carlito_syrichta ENSTSYP00000026796 95.2128 93.617 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 94.9333 panthera_tigris_altaica ENSPTIP00000012488 97.6127 94.4297 ENSG00000124795 homo_sapiens ENSP00000498653 95.7333 90.9333 rattus_norvegicus ENSRNOP00000089065 92.0513 87.4359 ENSG00000124795 homo_sapiens ENSP00000498653 43.2 38.6667 prolemur_simus ENSPSMP00000022941 86.1702 77.1277 ENSG00000124795 homo_sapiens ENSP00000498653 95.2 90.1333 microtus_ochrogaster ENSMOCP00000022458 94.1953 89.1821 ENSG00000124795 homo_sapiens ENSP00000498653 71.4667 69.0667 sorex_araneus ENSSARP00000008282 82.2086 79.4479 ENSG00000124795 homo_sapiens ENSP00000498653 89.0667 83.2 peromyscus_maniculatus_bairdii ENSPEMP00000031581 84.557 78.9873 ENSG00000124795 homo_sapiens ENSP00000498653 85.6 81.0667 peromyscus_maniculatus_bairdii ENSPEMP00000019517 92.5072 87.6081 ENSG00000124795 homo_sapiens ENSP00000498653 96.8 92.8 bos_mutus ENSBMUP00000016870 96.8 92.8 ENSG00000124795 homo_sapiens ENSP00000498653 91.2 85.8667 mus_spicilegus ENSMSIP00000000303 86.802 81.7259 ENSG00000124795 homo_sapiens ENSP00000498653 95.7333 90.9333 cricetulus_griseus_chok1gshd ENSCGRP00001003997 93.2467 88.5714 ENSG00000124795 homo_sapiens ENSP00000498653 75.4667 66.1333 cricetulus_griseus_chok1gshd ENSCGRP00001011961 86.0182 75.3799 ENSG00000124795 homo_sapiens ENSP00000498653 86.4 82.9333 pteropus_vampyrus ENSPVAP00000010217 76.5957 73.5225 ENSG00000124795 homo_sapiens ENSP00000498653 86.1333 84.2667 myotis_lucifugus ENSMLUP00000014895 98.7768 96.6361 ENSG00000124795 homo_sapiens ENSP00000498653 93.8667 87.2 vombatus_ursinus ENSVURP00010002476 94.1176 87.4332 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 93.3333 rhinolophus_ferrumequinum ENSRFEP00010016836 95.0392 91.3838 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 94.4 neovison_vison ENSNVIP00000024722 97.8552 94.9062 ENSG00000124795 homo_sapiens ENSP00000498653 96.8 92.8 bos_taurus ENSBTAP00000017097 96.8 92.8 ENSG00000124795 homo_sapiens ENSP00000498653 32 29.0667 heterocephalus_glaber_female ENSHGLP00000042608 86.9565 78.9855 ENSG00000124795 homo_sapiens ENSP00000498653 46.4 44.2667 rhinopithecus_bieti ENSRBIP00000003050 90.1554 86.0104 ENSG00000124795 homo_sapiens ENSP00000498653 97.3333 93.6 canis_lupus_dingo ENSCAFP00020012822 96.5608 92.8571 ENSG00000124795 homo_sapiens ENSP00000498653 96.5333 92.8 canis_lupus_dingo ENSCAFP00020014810 95.5145 91.8206 ENSG00000124795 homo_sapiens ENSP00000498653 48 45.8667 sciurus_vulgaris ENSSVLP00005017486 94.7368 90.5263 ENSG00000124795 homo_sapiens ENSP00000498653 93.3333 87.7333 phascolarctos_cinereus ENSPCIP00000040569 93.5829 87.9679 ENSG00000124795 homo_sapiens ENSP00000498653 97.0667 92.8 procavia_capensis ENSPCAP00000011186 85.8491 82.0755 ENSG00000124795 homo_sapiens ENSP00000498653 95.7333 89.3333 nannospalax_galili ENSNGAP00000014934 96.2467 89.8123 ENSG00000124795 homo_sapiens ENSP00000498653 96.5333 92.2667 bos_grunniens ENSBGRP00000012565 95.2632 91.0526 ENSG00000124795 homo_sapiens ENSP00000498653 74.4 66.9333 chinchilla_lanigera ENSCLAP00000021877 89.1374 80.1917 ENSG00000124795 homo_sapiens ENSP00000498653 96.2667 92.5333 chinchilla_lanigera ENSCLAP00000002707 96.2667 92.5333 ENSG00000124795 homo_sapiens ENSP00000498653 46.6667 43.7333 cervus_hanglu_yarkandensis ENSCHYP00000023168 84.1346 78.8462 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 94.4 catagonus_wagneri ENSCWAP00000017486 97.8723 94.1489 ENSG00000124795 homo_sapiens ENSP00000498653 85.3333 82.9333 ictidomys_tridecemlineatus ENSSTOP00000017320 97.8593 95.107 ENSG00000124795 homo_sapiens ENSP00000498653 96 93.3333 otolemur_garnettii ENSOGAP00000006937 98.0926 95.3678 ENSG00000124795 homo_sapiens ENSP00000498653 98.1333 97.3333 cebus_imitator ENSCCAP00000027672 94.359 93.5897 ENSG00000124795 homo_sapiens ENSP00000498653 86.9333 81.3333 urocitellus_parryii ENSUPAP00010025269 96.4497 90.2367 ENSG00000124795 homo_sapiens ENSP00000498653 49.6 45.6 moschus_moschiferus ENSMMSP00000020595 91.6256 84.2365 ENSG00000124795 homo_sapiens ENSP00000498653 94.4 93.3333 rhinopithecus_roxellana ENSRROP00000016761 97.7901 96.6851 ENSG00000124795 homo_sapiens ENSP00000498653 88.2667 84.2667 rhinopithecus_roxellana ENSRROP00000039888 93.2394 89.0141 ENSG00000124795 homo_sapiens ENSP00000498653 80.2667 77.6 rhinopithecus_roxellana ENSRROP00000021252 94.0625 90.9375 ENSG00000124795 homo_sapiens ENSP00000498653 94.9333 90.1333 mus_pahari MGP_PahariEiJ_P0040864 94.1799 89.418 ENSG00000124795 homo_sapiens ENSP00000498653 98.6667 96.8 propithecus_coquereli ENSPCOP00000029149 98.4043 96.5426 ENSG00000124795 homo_sapiens ENSP00000498653 53.0667 34.4 drosophila_melanogaster FBpp0099856 29.7459 19.2825 ENSG00000124795 homo_sapiens ENSP00000498653 36.5333 27.2 petromyzon_marinus ENSPMAP00000002347 57.563 42.8571 ENSG00000124795 homo_sapiens ENSP00000498653 63.7333 45.3333 eptatretus_burgeri ENSEBUP00000013702 57.4519 40.8654 ENSG00000124795 homo_sapiens ENSP00000498653 74.6667 58.1333 callorhinchus_milii ENSCMIP00000018398 68.4597 53.3007 ENSG00000124795 homo_sapiens ENSP00000498653 73.0667 56.8 lepisosteus_oculatus ENSLOCP00000007153 60.0877 46.7105 ENSG00000124795 homo_sapiens ENSP00000498653 62.1333 44.8 clupea_harengus ENSCHAP00000000941 48.7448 35.1464 ENSG00000124795 homo_sapiens ENSP00000498653 60.2667 42.1333 danio_rerio ENSDARP00000058585 51.0158 35.6659 ENSG00000124795 homo_sapiens ENSP00000498653 35.7333 24 carassius_auratus ENSCARP00000086536 54.0323 36.2903 ENSG00000124795 homo_sapiens ENSP00000498653 58.6667 41.3333 carassius_auratus ENSCARP00000121113 49.3274 34.7534 ENSG00000124795 homo_sapiens ENSP00000498653 53.3333 35.4667 carassius_auratus ENSCARP00000072229 48.7805 32.439 ENSG00000124795 homo_sapiens ENSP00000498653 57.3333 38.6667 carassius_auratus ENSCARP00000086592 47.8842 32.294 ENSG00000124795 homo_sapiens ENSP00000498653 60.8 41.8667 astyanax_mexicanus ENSAMXP00000043332 53.3958 36.7682 ENSG00000124795 homo_sapiens ENSP00000498653 57.8667 40.8 ictalurus_punctatus ENSIPUP00000030732 50.1155 35.3349 ENSG00000124795 homo_sapiens ENSP00000498653 59.2 42.6667 esox_lucius ENSELUP00000031789 47.7419 34.4086 ENSG00000124795 homo_sapiens ENSP00000498653 58.4 40.5333 electrophorus_electricus ENSEEEP00000049026 48.7751 33.853 ENSG00000124795 homo_sapiens ENSP00000498653 59.4667 41.8667 oncorhynchus_kisutch ENSOKIP00005076708 45.5102 32.0408 ENSG00000124795 homo_sapiens ENSP00000498653 59.2 42.1333 oncorhynchus_kisutch ENSOKIP00005024065 44.4 31.6 ENSG00000124795 homo_sapiens ENSP00000498653 42.9333 31.7333 oncorhynchus_mykiss ENSOMYP00000008686 63.8889 47.2222 ENSG00000124795 homo_sapiens ENSP00000498653 59.4667 42.1333 oncorhynchus_mykiss ENSOMYP00000005792 48.5839 34.4227 ENSG00000124795 homo_sapiens ENSP00000498653 60 41.6 salmo_salar ENSSSAP00000065267 48.1799 33.4047 ENSG00000124795 homo_sapiens ENSP00000498653 60 42.4 salmo_salar ENSSSAP00000063421 47.6695 33.6864 ENSG00000124795 homo_sapiens ENSP00000498653 59.2 42.4 salmo_trutta ENSSTUP00000019688 47.1338 33.758 ENSG00000124795 homo_sapiens ENSP00000498653 60 41.6 salmo_trutta ENSSTUP00000093438 47.3684 32.8421 ENSG00000124795 homo_sapiens ENSP00000498653 49.3333 34.6667 gadus_morhua ENSGMOP00000006853 47.6804 33.5052 ENSG00000124795 homo_sapiens ENSP00000498653 48.2667 29.8667 fundulus_heteroclitus ENSFHEP00000028659 45.3634 28.0702 ENSG00000124795 homo_sapiens ENSP00000498653 55.7333 37.6 poecilia_reticulata ENSPREP00000022622 52.1197 35.1621 ENSG00000124795 homo_sapiens ENSP00000498653 57.0667 37.6 xiphophorus_maculatus ENSXMAP00000001165 54.1772 35.6962 ENSG00000124795 homo_sapiens ENSP00000498653 55.4667 35.4667 oryzias_latipes ENSORLP00000025794 45.3159 28.976 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 40.5333 oreochromis_niloticus ENSONIP00000001941 41.9417 29.5146 ENSG00000124795 homo_sapiens ENSP00000498653 45.3333 30.4 haplochromis_burtoni ENSHBUP00000007766 45.4545 30.4813 ENSG00000124795 homo_sapiens ENSP00000498653 58.4 41.0667 astatotilapia_calliptera ENSACLP00000022671 51.049 35.8974 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 42.1333 sparus_aurata ENSSAUP00010026427 44.9064 32.8482 ENSG00000124795 homo_sapiens ENSP00000498653 55.2 41.0667 lates_calcarifer ENSLCAP00010004086 47.5862 35.4023 ENSG00000124795 homo_sapiens ENSP00000498653 72.8 57.0667 xenopus_tropicalis ENSXETP00000059248 69.2893 54.3147 ENSG00000124795 homo_sapiens ENSP00000498653 89.0667 81.6 chrysemys_picta_bellii ENSCPBP00000023598 83.5 76.5 ENSG00000124795 homo_sapiens ENSP00000498653 83.4667 77.0667 sphenodon_punctatus ENSSPUP00000012752 88.6686 81.8697 ENSG00000124795 homo_sapiens ENSP00000498653 85.3333 77.0667 crocodylus_porosus ENSCPRP00005004460 79.2079 71.5347 ENSG00000124795 homo_sapiens ENSP00000498653 84.2667 76.2667 laticauda_laticaudata ENSLLTP00000000197 88.0223 79.6657 ENSG00000124795 homo_sapiens ENSP00000498653 88 78.9333 notechis_scutatus ENSNSUP00000023159 87.5332 78.5146 ENSG00000124795 homo_sapiens ENSP00000498653 84 76.5333 pseudonaja_textilis ENSPTXP00000000963 88.7324 80.8451 ENSG00000124795 homo_sapiens ENSP00000498653 88.8 81.0667 anas_platyrhynchos_platyrhynchos ENSAPLP00000028379 81.4181 74.3276 ENSG00000124795 homo_sapiens ENSP00000498653 89.0667 80.2667 gallus_gallus ENSGALP00010010098 59.0106 53.1802 ENSG00000124795 homo_sapiens ENSP00000498653 88.8 80.5333 meleagris_gallopavo ENSMGAP00000029519 81.8182 74.2015 ENSG00000124795 homo_sapiens ENSP00000498653 88 80.5333 serinus_canaria ENSSCAP00000000989 89.1892 81.6216 ENSG00000124795 homo_sapiens ENSP00000498653 88.5333 80.8 parus_major ENSPMJP00000024805 90.2174 82.337 ENSG00000124795 homo_sapiens ENSP00000498653 78.6667 73.0667 anolis_carolinensis ENSACAP00000040470 88.8554 82.5301 ENSG00000124795 homo_sapiens ENSP00000498653 78.6667 70.4 naja_naja ENSNNAP00000020234 83.0986 74.3662 ENSG00000124795 homo_sapiens ENSP00000498653 83.7333 75.7333 podarcis_muralis ENSPMRP00000009573 89.4587 80.9117 ENSG00000124795 homo_sapiens ENSP00000498653 88 80.2667 geospiza_fortis ENSGFOP00000009374 86.3874 78.7958 ENSG00000124795 homo_sapiens ENSP00000498653 86.4 78.9333 taeniopygia_guttata ENSTGUP00000006448 88.7671 81.0959 ENSG00000124795 homo_sapiens ENSP00000498653 72 54.4 erpetoichthys_calabaricus ENSECRP00000031125 72.3861 54.6917 ENSG00000124795 homo_sapiens ENSP00000498653 42.6667 28.2667 kryptolebias_marmoratus ENSKMAP00000015539 48.7805 32.3171 ENSG00000124795 homo_sapiens ENSP00000498653 84 76.8 salvator_merianae ENSSMRP00000007000 86.7769 79.3388 ENSG00000124795 homo_sapiens ENSP00000498653 56.8 35.7333 oryzias_javanicus ENSOJAP00000019654 46.9163 29.5154 ENSG00000124795 homo_sapiens ENSP00000498653 52.2667 36.5333 amphilophus_citrinellus ENSACIP00000004939 41.2632 28.8421 ENSG00000124795 homo_sapiens ENSP00000498653 54.1333 37.6 dicentrarchus_labrax ENSDLAP00005082832 52.4548 36.4341 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 43.4667 amphiprion_percula ENSAPEP00000029543 46.9565 35.4348 ENSG00000124795 homo_sapiens ENSP00000498653 55.2 34.9333 oryzias_sinensis ENSOSIP00000049635 47.1526 29.8405 ENSG00000124795 homo_sapiens ENSP00000498653 89.6 82.1333 pelodiscus_sinensis ENSPSIP00000015261 89.3617 81.9149 ENSG00000124795 homo_sapiens ENSP00000498653 88.5333 81.8667 gopherus_evgoodei ENSGEVP00005003316 89.9729 83.1978 ENSG00000124795 homo_sapiens ENSP00000498653 76.8 72.2667 chelonoidis_abingdonii ENSCABP00000003314 92.9032 87.4194 ENSG00000124795 homo_sapiens ENSP00000498653 56 41.3333 seriola_dumerili ENSSDUP00000027678 47.191 34.8315 ENSG00000124795 homo_sapiens ENSP00000498653 54.4 37.3333 cottoperca_gobio ENSCGOP00000034169 41.129 28.2258 ENSG00000124795 homo_sapiens ENSP00000498653 74.9333 66.9333 struthio_camelus_australis ENSSCUP00000018406 69.7271 62.2829 ENSG00000124795 homo_sapiens ENSP00000498653 89.3333 81.3333 anser_brachyrhynchus ENSABRP00000014972 88.1579 80.2632 ENSG00000124795 homo_sapiens ENSP00000498653 52.5333 37.0667 gasterosteus_aculeatus ENSGACP00000001221 59.697 42.1212 ENSG00000124795 homo_sapiens ENSP00000498653 57.0667 41.6 cynoglossus_semilaevis ENSCSEP00000000868 47.5556 34.6667 ENSG00000124795 homo_sapiens ENSP00000498653 56 35.4667 poecilia_formosa ENSPFOP00000003135 59.4901 37.6771 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 38.4 poecilia_formosa ENSPFOP00000003059 48.9796 32.6531 ENSG00000124795 homo_sapiens ENSP00000498653 58.9333 41.6 myripristis_murdjan ENSMMDP00005023602 48.4649 34.2105 ENSG00000124795 homo_sapiens ENSP00000498653 56.2667 41.6 sander_lucioperca ENSSLUP00000035940 45.9695 33.9869 ENSG00000124795 homo_sapiens ENSP00000498653 89.6 80 strigops_habroptila ENSSHBP00005018107 90.8108 81.0811 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 43.4667 amphiprion_ocellaris ENSAOCP00000012663 46.8547 35.3579 ENSG00000124795 homo_sapiens ENSP00000498653 84.8 79.4667 terrapene_carolina_triunguis ENSTMTP00000001164 82.8125 77.6042 ENSG00000124795 homo_sapiens ENSP00000498653 58.6667 42.1333 hucho_hucho ENSHHUP00000050382 47.4138 34.0517 ENSG00000124795 homo_sapiens ENSP00000498653 58.6667 41.6 hucho_hucho ENSHHUP00000045748 48.4581 34.3612 ENSG00000124795 homo_sapiens ENSP00000498653 56 40.2667 betta_splendens ENSBSLP00000037370 47.9452 34.4749 ENSG00000124795 homo_sapiens ENSP00000498653 59.7333 42.1333 pygocentrus_nattereri ENSPNAP00000016132 51.9722 36.6589 ENSG00000124795 homo_sapiens ENSP00000498653 55.4667 40 anabas_testudineus ENSATEP00000028741 44.6352 32.1888 ENSG00000124795 homo_sapiens ENSP00000498653 58.1333 42.4 seriola_lalandi_dorsalis ENSSLDP00000020287 48.337 35.255 ENSG00000124795 homo_sapiens ENSP00000498653 38.6667 25.6 labrus_bergylta ENSLBEP00000012066 54.3071 35.9551 ENSG00000124795 homo_sapiens ENSP00000498653 57.3333 39.7333 labrus_bergylta ENSLBEP00000016342 47.3568 32.8194 ENSG00000124795 homo_sapiens ENSP00000498653 53.6 37.3333 pundamilia_nyererei ENSPNYP00000019586 47.0726 32.7869 ENSG00000124795 homo_sapiens ENSP00000498653 57.8667 41.6 mastacembelus_armatus ENSMAMP00000027449 46.8683 33.6933 ENSG00000124795 homo_sapiens ENSP00000498653 58.9333 41.6 oncorhynchus_tshawytscha ENSOTSP00005047801 48.0435 33.913 ENSG00000124795 homo_sapiens ENSP00000498653 44 30.6667 acanthochromis_polyacanthus ENSAPOP00000004208 52.0505 36.2776 ENSG00000124795 homo_sapiens ENSP00000498653 84.5333 76.5333 aquila_chrysaetos_chrysaetos ENSACCP00020021124 88.0556 79.7222 ENSG00000124795 homo_sapiens ENSP00000498653 57.3333 39.7333 nothobranchius_furzeri ENSNFUP00015015644 46.7391 32.3913 ENSG00000124795 homo_sapiens ENSP00000498653 56.5333 40.8 cyprinodon_variegatus ENSCVAP00000018377 48.9607 35.3349 ENSG00000124795 homo_sapiens ENSP00000498653 58.4 41.0667 denticeps_clupeoides ENSDCDP00000010552 48.5588 34.1463 ENSG00000124795 homo_sapiens ENSP00000498653 51.7333 36.5333 larimichthys_crocea ENSLCRP00005014594 29.709 20.9801 ENSG00000124795 homo_sapiens ENSP00000498653 58.9333 39.4667 takifugu_rubripes ENSTRUP00000025673 53.253 35.6627 ENSG00000124795 homo_sapiens ENSP00000498653 87.2 79.2 ficedula_albicollis ENSFALP00000020657 86.2797 78.3641 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 40.8 hippocampus_comes ENSHCOP00000022674 48.9796 34.6939 ENSG00000124795 homo_sapiens ENSP00000498653 60 42.4 cyprinus_carpio_carpio ENSCCRP00000027065 47.0711 33.2636 ENSG00000124795 homo_sapiens ENSP00000498653 61.6 44.2667 cyprinus_carpio_carpio ENSCCRP00000170004 50.547 36.3239 ENSG00000124795 homo_sapiens ENSP00000498653 67.7333 58.9333 coturnix_japonica ENSCJPP00005022531 86.1017 74.9153 ENSG00000124795 homo_sapiens ENSP00000498653 40.8 25.6 poecilia_latipinna ENSPLAP00000007063 56.4576 35.4244 ENSG00000124795 homo_sapiens ENSP00000498653 58.9333 41.0667 sinocyclocheilus_grahami ENSSGRP00000010048 47.2222 32.906 ENSG00000124795 homo_sapiens ENSP00000498653 60.2667 41.3333 sinocyclocheilus_grahami ENSSGRP00000039080 50.3341 34.5212 ENSG00000124795 homo_sapiens ENSP00000498653 58.6667 41.3333 maylandia_zebra ENSMZEP00005031767 51.2821 36.1305 ENSG00000124795 homo_sapiens ENSP00000498653 51.2 33.3333 tetraodon_nigroviridis ENSTNIP00000004065 55.4913 36.1272 ENSG00000124795 homo_sapiens ENSP00000498653 57.6 40.8 paramormyrops_kingsleyae ENSPKIP00000014841 47.8936 33.9246 ENSG00000124795 homo_sapiens ENSP00000498653 59.4667 41.3333 scleropages_formosus ENSSFOP00015017798 49.2274 34.2163 ENSG00000124795 homo_sapiens ENSP00000498653 80 64.8 leptobrachium_leishanense ENSLLEP00000020452 75.9494 61.519 ENSG00000124795 homo_sapiens ENSP00000498653 52.8 35.4667 scophthalmus_maximus ENSSMAP00000029878 53.8043 36.1413 ENSG00000124795 homo_sapiens ENSP00000498653 56 34.9333 oryzias_melastigma ENSOMEP00000003302 48.0549 29.9771
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003677 enables DNA binding 1 IEA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 NAS Homo_sapiens(9606) Component GO:0006338 involved_in chromatin remodeling 1 NAS Homo_sapiens(9606) Process GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 TAS Homo_sapiens(9606) Process GO:0006366 involved_in transcription by RNA polymerase II 1 TAS Homo_sapiens(9606) Process GO:0007165 involved_in signal transduction 1 TAS Homo_sapiens(9606) Process GO:0019079 involved_in viral genome replication 1 TAS Homo_sapiens(9606) Process GO:0035066 involved_in positive regulation of histone acetylation 1 NAS Homo_sapiens(9606) Process GO:0042393 enables histone binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0043292 located_in contractile fiber 1 IEA Homo_sapiens(9606) Component GO:0045943 involved_in positive regulation of transcription by RNA polymerase I 1 NAS Homo_sapiens(9606) Process GO:0045944 involved_in positive regulation of transcription by RNA polymerase II 1 NAS Homo_sapiens(9606) Process GO:0045945 involved_in positive regulation of transcription by RNA polymerase III 1 IDA Homo_sapiens(9606) Process GO:0110016 part_of B-WICH complex 1 IDA Homo_sapiens(9606) Component GO:2000779 involved_in regulation of double-strand break repair 2 IBA,IMP Homo_sapiens(9606) Process GO:2001032 involved_in regulation of double-strand break repair via nonhomologous end joining 1 IEA Homo_sapiens(9606) Process
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