Ensembl ID
ENSG00000124795
Gene ID
7913
Accession
2768
Gene Symbol
DEK
Alias
D6S231E
Full Name
DEK proto-oncogene
Position
6 : 18223860 - 18264548
Length
40689 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
ENSG00000124795 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000124795
DEK
0.62
3.14e-12
HNSC
ENSG00000124795
DEK
0.92
2.52e-23
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000124795
DEK
AMLs
10908574
ENSG00000124795
DEK
cancer
12483538
ENSG00000124795
DEK
tumors
12875971
ENSG00000124795
DEK
acute myeloid leukemia (AML)
1384675
ENSG00000124795
DEK
bladder cancer
14695341
ENSG00000124795
DEK
acute myeloid leukemia (AML)
14738146
ENSG00000124795
DEK
acute myeloid leukemia (AML)
15380347
ENSG00000124795
DEK
cancer
15766865
ENSG00000124795
DEK
bladder cancer
15876350
ENSG00000124795
DEK
AML
15973457
ENSG00000124795
DEK
cancer
15987677
ENSG00000124795
DEK
tumors
16180235
ENSG00000124795
DEK
Cervical cancer
16254365
ENSG00000124795
DEK
acute myeloid leukemia (AML)
16638187
ENSG00000124795
DEK
AMLs
16645213
ENSG00000124795
DEK
AML
16696975
ENSG00000124795
DEK
tumor
16721057
ENSG00000124795
DEK
cancers
16809543
ENSG00000124795
DEK
cancer
16829531
ENSG00000124795
DEK
cancer
16894028
ENSG00000124795
DEK
tumors
17099872
ENSG00000124795
DEK
tumor
17397536
ENSG00000124795
DEK
tumor
17437278
ENSG00000124795
DEK
tumour
17635577
ENSG00000124795
DEK
tumor
18211953
ENSG00000124795
DEK
AML
18227428
ENSG00000124795
DEK
uterine cervical cancers
18477217
ENSG00000124795
DEK
cancers
19036808
ENSG00000124795
DEK
tumor
19223548
ENSG00000124795
DEK
ovarian tumors
19563407
ENSG00000124795
DEK
tumor
19679545
ENSG00000124795
DEK
AML with recurrent genetic abnormalities
19860179
ENSG00000124795
DEK
cancer
20501624
ENSG00000124795
DEK
tumor
20543864
ENSG00000124795
DEK
cancer
21282377
ENSG00000124795
DEK
breast cancer
21317931
ENSG00000124795
DEK
cancer
21653549
ENSG00000124795
DEK
bladder cancer
21663673
ENSG00000124795
DEK
cancer
21816114
ENSG00000124795
DEK
breast cancer
22360505
ENSG00000124795
DEK
tumors
22683420
ENSG00000124795
DEK
tumor
22765016
ENSG00000124795
DEK
tumor
22824167
ENSG00000124795
DEK
Breast Cancer
23071688
ENSG00000124795
DEK
cancer
23255114
ENSG00000124795
DEK
bladder cancer
23342256
ENSG00000124795
DEK
non-small cell lung cancer
23571382
ENSG00000124795
DEK
colorectal cancer
23902796
ENSG00000124795
DEK
tumor
24353627
ENSG00000124795
DEK
cancer
24563617
ENSG00000124795
DEK
AML
24602728
ENSG00000124795
DEK
HNSCC
24608431
ENSG00000124795
DEK
gastric cancer
24650035
ENSG00000124795
DEK
AML
24657637
ENSG00000124795
DEK
breast cancers
24954505
ENSG00000124795
DEK
Acute Myeloid Leukemia (AML)
25128083
ENSG00000124795
DEK
small cell lung cancer
25197373
ENSG00000124795
DEK
cancer
25216995
ENSG00000124795
DEK
Colorectal Cancer
25340858
ENSG00000124795
DEK
cancer
25347734
ENSG00000124795
DEK
cancer
25351213
ENSG00000124795
DEK
tumour
25515240
ENSG00000124795
DEK
prostate cancer
25544761
ENSG00000124795
DEK
cancers
25765544
ENSG00000124795
DEK
cancer
25773167
ENSG00000124795
DEK
AML
25794001
ENSG00000124795
DEK
cancer
25945971
ENSG00000124795
DEK
AML
26237023
ENSG00000124795
DEK
AML
26284582
ENSG00000124795
DEK
tumor
26425120
ENSG00000124795
DEK
AML
26436590
ENSG00000124795
DEK
breast cancer
26459608
ENSG00000124795
DEK
acute myeloid leukemia (AML)
26517539
ENSG00000124795
DEK
head and neck cancer
26527316
ENSG00000124795
DEK
tumor
26530274
ENSG00000124795
DEK
tumor
26722432
ENSG00000124795
DEK
tumor
26731982
ENSG00000124795
DEK
pancreatic cancer
26947878
ENSG00000124795
DEK
tumor
26988756
ENSG00000124795
DEK
tumor
26998084
ENSG00000124795
DEK
tumor
27057626
ENSG00000124795
DEK
tumor
27065320
ENSG00000124795
DEK
prostate cancer
27200299
ENSG00000124795
DEK
tumors
27499261
ENSG00000124795
DEK
breast cancer
27811057
ENSG00000124795
DEK
tumors
27893188
ENSG00000124795
DEK
tumor
27959420
ENSG00000124795
DEK
AML
28154779
ENSG00000124795
DEK
colon cancer
28169543
ENSG00000124795
DEK
tumors
28211617
ENSG00000124795
DEK
cancer
28317934
ENSG00000124795
DEK
acute myeloid leukemia (AML)
28318095
ENSG00000124795
DEK
cancer
28397013
ENSG00000124795
DEK
tumor
28423581
ENSG00000124795
DEK
Cancer
28530531
ENSG00000124795
DEK
tumor
28558019
ENSG00000124795
DEK
cancer
28558048
ENSG00000124795
DEK
breast cancer
28578385
ENSG00000124795
DEK
breast cancer
28627610
ENSG00000124795
DEK
astrocytic tumors
28670979
ENSG00000124795
DEK
prostate cancer
28805820
ENSG00000124795
DEK
tumors
28834425
ENSG00000124795
DEK
AML with minimal differentiation
28977979
ENSG00000124795
DEK
cancer
29082557
ENSG00000124795
DEK
cancer
29165587
ENSG00000124795
DEK
cancer
29175155
ENSG00000124795
DEK
breast cancer
29228721
ENSG00000124795
DEK
tumors
29228743
ENSG00000124795
DEK
tumor
29269732
ENSG00000124795
DEK
Tumor
29289845
ENSG00000124795
DEK
tumour
29409457
ENSG00000124795
DEK
cancer
29538372
ENSG00000124795
DEK
lung cancer
29844811
ENSG00000124795
DEK
tumor
29900883
ENSG00000124795
DEK
cancer
29957464
ENSG00000124795
DEK
AML
29988882
ENSG00000124795
DEK
tumor
30104710
ENSG00000124795
DEK
tumor
30262806
ENSG00000124795
DEK
Ovarian Cancer
30412857
ENSG00000124795
DEK
AML
30442503
ENSG00000124795
DEK
tumors
30637779
ENSG00000124795
DEK
acute myeloid leukemia (AML)
30669574
ENSG00000124795
DEK
Breast Cancer
30758703
ENSG00000124795
DEK
pancreatic cancer
30854097
ENSG00000124795
DEK
tumor
31011208
ENSG00000124795
DEK
tumors
31019846
ENSG00000124795
DEK
cancer
31189566
ENSG00000124795
DEK
Tumor
31336272
ENSG00000124795
DEK
cancers
31408463
ENSG00000124795
DEK
Gastric Cancer
31766266
ENSG00000124795
DEK
acute myeloid leukemia (AML)
7596189
ENSG00000124795
DEK
AML
8350633
ENSG00000124795
DEK
acute myeloid leukemia (AML)
8750194
ENSG00000124795
DEK
AML M2
9028159
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000124795
DEK
MESO
4e-04
high
show
ENSG00000124795
DEK
SARC
0.00079
high
show
ENSG00000124795
DEK
PAAD
0.0054
high
show
ENSG00000124795
DEK
UCEC
0.017
high
show
ENSG00000124795
DEK
ACC
0.00014
high
show
ENSG00000124795
DEK
HNSC
0.0014
low
show
ENSG00000124795
DEK
READ
0.024
low
show
ENSG00000124795
DEK
KICH
0.00015
high
show
ENSG00000124795
DEK
PCPG
0.023
high
show
ENSG00000124795
DEK
THYM
0.0022
low
show
ENSG00000124795
DEK
UCS
0.0073
low
show
ENSG00000124795
DEK
ESCA
0.033
high
show
ENSG00000124795
DEK
OV
0.0022
low
show
ENSG00000124795
DEK
KIRC
0.00038
low
show
ENSG00000124795
DEK
PRAD
0.0032
high
show
ENSG00000124795
DEK
LAML
0.039
high
show
ENSG00000124795
DEK
CESC
0.033
low
show
ENSG00000124795
DEK
LIHC
0.0015
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000124795
DEK
SARC
Del
0.839805
0.125116
0.538392
0.287938
ENSG00000124795
DEK
PAAD
Del
1.964460
0.070608
0.345696
0.391304
ENSG00000124795
DEK
ESCA
Del
2.955362
0.156514
0.422958
0.309783
ENSG00000124795
DEK
SKCM
Amp
4.528347
0.230812
0.744139
0.566757
ENSG00000124795
DEK
LIHC
Amp
2.143254
0.149461
0.742649
0.416216
ENSG00000124795
DEK
BLCA
Amp
18.214875
0.528370
0.783414
0.365196
ENSG00000124795
DEK
BRCA
Amp
1.819315
0.167120
0.573172
0.267593
ENSG00000124795
DEK
STAD
Del
1.351419
0.069967
0.377695
0.156463
ENSG00000124795
DEK
UCEC
Amp
1.094985
0.113207
0.600029
0.187384
ENSG00000124795
DEK
UVM
Amp
5.108221
0.407116
1.198392
0.562500
ENSG00000124795
DEK
OV
Amp
12.970951
0.595393
0.805303
0.526770
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