Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs snRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000124380 Gene ID 11017 Accession 30240
Symbol SNRNP27 Alias 27K;RY1 Full Name small nuclear ribonucleoprotein U4/U6.U5 subunit 27
Status Confidence Length 11620 bases Strand Plus strand
Position 2 : 69893956 - 69905575 RNA binding domain N.A.
Summary This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27172183 Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast. Amy Larson 2016-06-01 G3 (Bethesda, Md.)

Transcripts

Name Transcript ID bp Protein Translation ID
SNRNP27-201 ENST00000244227 1425 155aa ENSP00000244227
SNRNP27-202 ENST00000409116 1339 158aa ENSP00000386608
SNRNP27-203 ENST00000450162 766 155aa ENSP00000395144
SNRNP27-205 ENST00000488986 336 No protein -
SNRNP27-204 ENST00000487029 604 18aa ENSP00000430449

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124380

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124380homo_sapiensENSP00000244227100100pongo_abeliiENSPPYP00000013753100100
ENSG00000124380homo_sapiensENSP0000024422788.387182.5806ornithorhynchus_anatinusENSOANP0000003415952.091348.6692
ENSG00000124380homo_sapiensENSP0000024422766.451664.5161notamacropus_eugeniiENSMEUP0000001248410097.0874
ENSG00000124380homo_sapiensENSP0000024422792.258192.2581choloepus_hoffmanniENSCHOP00000002694100100
ENSG00000124380homo_sapiensENSP00000244227100100dasypus_novemcinctusENSDNOP00000031717100100
ENSG00000124380homo_sapiensENSP0000024422791.612989.6774echinops_telfairiENSETEP0000001408289.873487.9747
ENSG00000124380homo_sapiensENSP00000244227100100macaca_mulattaENSMMUP00000013388100100
ENSG00000124380homo_sapiensENSP00000244227100100tursiops_truncatusENSTTRP00000007091100100
ENSG00000124380homo_sapiensENSP00000244227100100equus_asinusENSEASP00005060229100100
ENSG00000124380homo_sapiensENSP0000024422792.903292.9032capra_hircusENSCHIP0000002931297.959297.9592
ENSG00000124380homo_sapiensENSP0000024422794.838794.1936capra_hircusENSCHIP0000000335996.710596.0526
ENSG00000124380homo_sapiensENSP0000024422789.677485.8064loxodonta_africanaENSLAFP0000001644389.102685.2564
ENSG00000124380homo_sapiensENSP00000244227100100panthera_leoENSPLOP00000017186100100
ENSG00000124380homo_sapiensENSP0000024422789.677487.0968oryctolagus_cuniculusENSOCUP0000003180189.677487.0968
ENSG00000124380homo_sapiensENSP0000024422710099.3548oryctolagus_cuniculusENSOCUP0000002181210099.3548
ENSG00000124380homo_sapiensENSP0000024422780.645279.3548canis_lupus_familiarisENSCAFP0084503722853.191552.3404
ENSG00000124380homo_sapiensENSP00000244227100100panthera_pardusENSPPRP00000021641100100
ENSG00000124380homo_sapiensENSP00000244227100100marmota_marmota_marmotaENSMMMP00000005501100100
ENSG00000124380homo_sapiensENSP0000024422794.838794.8387balaenoptera_musculusENSBMSP0001002244691.304391.3043
ENSG00000124380homo_sapiensENSP00000244227100100cavia_porcellusENSCPOP00000006452100100
ENSG00000124380homo_sapiensENSP00000244227100100ursus_americanusENSUAMP00000000168100100
ENSG00000124380homo_sapiensENSP0000024422798.709796.7742monodelphis_domesticaENSMODP0000001426398.709796.7742
ENSG00000124380homo_sapiensENSP00000244227100100bison_bison_bisonENSBBBP00000008871100100
ENSG00000124380homo_sapiensENSP0000024422798.709798.7097sus_scrofaENSSSCP0000002089198.709798.7097
ENSG00000124380homo_sapiensENSP0000024422776.774273.5484octodon_degusENSODEP0000000339293.700889.7638
ENSG00000124380homo_sapiensENSP0000024422799.354899.3548octodon_degusENSODEP0000001308799.354899.3548
ENSG00000124380homo_sapiensENSP0000024422798.064597.4194jaculus_jaculusENSJJAP0000002218598.064597.4194
ENSG00000124380homo_sapiensENSP00000244227100100ovis_aries_rambouilletENSOARP00020007652100100
ENSG00000124380homo_sapiensENSP00000244227100100ursus_maritimusENSUMAP00000029589100100
ENSG00000124380homo_sapiensENSP0000024422799.354894.8387ochotona_princepsENSOPRP0000000596399.354894.8387
ENSG00000124380homo_sapiensENSP00000244227100100delphinapterus_leucasENSDLEP00000007284100100
ENSG00000124380homo_sapiensENSP0000024422796.12994.8387dipodomys_ordiiENSDORP0000000941995.512894.2308
ENSG00000124380homo_sapiensENSP0000024422791.612989.0323mustela_putorius_furoENSMPUP0000000699391.612989.0323
ENSG00000124380homo_sapiensENSP00000244227100100saimiri_boliviensis_boliviensisENSSBOP00000033400100100
ENSG00000124380homo_sapiensENSP0000024422787.741987.0968vicugna_pacosENSVPAP0000000162297.142996.4286
ENSG00000124380homo_sapiensENSP00000244227100100chlorocebus_sabaeusENSCSAP00000011213100100
ENSG00000124380homo_sapiensENSP0000024422710099.3548mesocricetus_auratusENSMAUP0000002534410099.3548
ENSG00000124380homo_sapiensENSP00000244227100100phocoena_sinusENSPSNP00000026647100100
ENSG00000124380homo_sapiensENSP00000244227100100camelus_dromedariusENSCDRP00005013183100100
ENSG00000124380homo_sapiensENSP0000024422799.354898.7097carlito_syrichtaENSTSYP0000002175399.354898.7097
ENSG00000124380homo_sapiensENSP00000244227100100panthera_tigris_altaicaENSPTIP00000003198100100
ENSG00000124380homo_sapiensENSP0000024422785.806483.2258rattus_norvegicusENSRNOP0000008546092.361189.5833
ENSG00000124380homo_sapiensENSP0000024422798.709797.4194rattus_norvegicusENSRNOP0000006027698.709797.4194
ENSG00000124380homo_sapiensENSP0000024422798.709798.0645microtus_ochrogasterENSMOCP0000001675698.709798.0645
ENSG00000124380homo_sapiensENSP0000024422798.709798.0645peromyscus_maniculatus_bairdiiENSPEMP0000000499898.709798.0645
ENSG00000124380homo_sapiensENSP0000024422788.387182.5806peromyscus_maniculatus_bairdiiENSPEMP0000000374092.567686.4865
ENSG00000124380homo_sapiensENSP00000244227100100bos_mutusENSBMUP00000027622100100
ENSG00000124380homo_sapiensENSP0000024422710099.3548cricetulus_griseus_chok1gshdENSCGRP0000100470110099.3548
ENSG00000124380homo_sapiensENSP00000244227100100pteropus_vampyrusENSPVAP00000001167100100
ENSG00000124380homo_sapiensENSP0000024422796.12994.1936myotis_lucifugusENSMLUP0000001516098.026396.0526
ENSG00000124380homo_sapiensENSP0000024422799.354897.4194vombatus_ursinusENSVURP0001001541599.354897.4194
ENSG00000124380homo_sapiensENSP0000024422798.064598.0645rhinolophus_ferrumequinumENSRFEP0001002282797.435997.4359
ENSG00000124380homo_sapiensENSP0000024422797.419497.4194neovison_visonENSNVIP0000000450898.051998.0519
ENSG00000124380homo_sapiensENSP00000244227100100bos_taurusENSBTAP00000050475100100
ENSG00000124380homo_sapiensENSP0000024422794.193693.5484heterocephalus_glaber_femaleENSHGLP0000005577091.2590.625
ENSG00000124380homo_sapiensENSP0000024422798.709798.0645canis_lupus_dingoENSCAFP0002000206998.709798.0645
ENSG00000124380homo_sapiensENSP00000244227100100sciurus_vulgarisENSSVLP00005019977100100
ENSG00000124380homo_sapiensENSP0000024422799.354897.4194phascolarctos_cinereusENSPCIP0000003802099.354897.4194
ENSG00000124380homo_sapiensENSP0000024422765.806465.8064procavia_capensisENSPCAP0000000106199.029199.0291
ENSG00000124380homo_sapiensENSP0000024422797.419496.7742nannospalax_galiliENSNGAP0000001760094.37593.75
ENSG00000124380homo_sapiensENSP00000244227100100bos_grunniensENSBGRP00000007918100100
ENSG00000124380homo_sapiensENSP00000244227100100chinchilla_lanigeraENSCLAP00000019014100100
ENSG00000124380homo_sapiensENSP00000244227100100cervus_hanglu_yarkandensisENSCHYP00000017706100100
ENSG00000124380homo_sapiensENSP0000024422776.774273.5484cervus_hanglu_yarkandensisENSCHYP0000002485157.211554.8077
ENSG00000124380homo_sapiensENSP00000244227100100ictidomys_tridecemlineatusENSSTOP00000026979100100
ENSG00000124380homo_sapiensENSP00000244227100100urocitellus_parryiiENSUPAP00010006776100100
ENSG00000124380homo_sapiensENSP00000244227100100moschus_moschiferusENSMMSP00000013754100100
ENSG00000124380homo_sapiensENSP0000024422798.709797.4194mus_pahariMGP_PahariEiJ_P005091298.709797.4194
ENSG00000124380homo_sapiensENSP0000024422767.096847.0968caenorhabditis_elegansR05D11.7.167.096847.0968
ENSG00000124380homo_sapiensENSP0000024422776.774264.5161eptatretus_burgeriENSEBUP0000000534879.333366.6667
ENSG00000124380homo_sapiensENSP0000024422778.064571.6129callorhinchus_miliiENSCMIP0000003039088.321281.0219
ENSG00000124380homo_sapiensENSP0000024422776.12969.0323latimeria_chalumnaeENSLACP0000001977688.721880.4511
ENSG00000124380homo_sapiensENSP0000024422789.677480.6452lepisosteus_oculatusENSLOCP0000001885086.335477.6398
ENSG00000124380homo_sapiensENSP0000024422789.677480clupea_harengusENSCHAP0000006225090.259780.5195
ENSG00000124380homo_sapiensENSP0000024422790.967778.7097danio_rerioENSDARP0000005165489.240577.2152
ENSG00000124380homo_sapiensENSP0000024422789.677478.7097carassius_auratusENSCARP0000003692682.738172.619
ENSG00000124380homo_sapiensENSP0000024422792.903281.2903astyanax_mexicanusENSAMXP0000003222592.307780.7692
ENSG00000124380homo_sapiensENSP0000024422792.258184.5161ictalurus_punctatusENSIPUP0000002538688.271680.8642
ENSG00000124380homo_sapiensENSP0000024422785.806473.5484esox_luciusENSELUP0000000471161.290352.5346
ENSG00000124380homo_sapiensENSP0000024422791.612980.6452electrophorus_electricusENSEEEP0000002358089.873479.1139
ENSG00000124380homo_sapiensENSP0000024422790.967778.7097oncorhynchus_kisutchENSOKIP0000501718088.12576.25
ENSG00000124380homo_sapiensENSP0000024422747.741938.0645oncorhynchus_kisutchENSOKIP0000500222384.090967.0455
ENSG00000124380homo_sapiensENSP0000024422790.967778.0645oncorhynchus_mykissENSOMYP0000008197388.12575.625
ENSG00000124380homo_sapiensENSP0000024422786.451673.5484salmo_salarENSSSAP0000010912770.899560.3175
ENSG00000124380homo_sapiensENSP0000024422788.387174.8387salmo_truttaENSSTUP0000005112187.261173.8854
ENSG00000124380homo_sapiensENSP0000024422790.967778.7097salmo_truttaENSSTUP0000000229788.12576.25
ENSG00000124380homo_sapiensENSP0000024422789.032380fundulus_heteroclitusENSFHEP0000002454385.714377.0186
ENSG00000124380homo_sapiensENSP0000024422785.806476.7742xiphophorus_maculatusENSXMAP0000004166084.713475.7962
ENSG00000124380homo_sapiensENSP0000024422789.677474.8387oryzias_latipesENSORLP0000001935185.802571.6049
ENSG00000124380homo_sapiensENSP0000024422787.096878.7097cyclopterus_lumpusENSCLMP0000503891187.096878.7097
ENSG00000124380homo_sapiensENSP0000024422785.806476.7742oreochromis_niloticusENSONIP0000001998583.12574.375
ENSG00000124380homo_sapiensENSP0000024422792.258182.5806haplochromis_burtoniENSHBUP0000002046190.506381.0127
ENSG00000124380homo_sapiensENSP0000024422788.387178.0645astatotilapia_callipteraENSACLP0000000424371.727763.3508
ENSG00000124380homo_sapiensENSP0000024422790.967779.3548sparus_aurataENSSAUP0001005338988.12576.875
ENSG00000124380homo_sapiensENSP0000024422769.677457.4194lates_calcariferENSLCAP0001003488856.544546.5969
ENSG00000124380homo_sapiensENSP0000024422794.193686.4516xenopus_tropicalisENSXETP0000001864493.589785.8974
ENSG00000124380homo_sapiensENSP0000024422790.967785.1613chrysemys_picta_belliiENSCPBP0000000462880.113675
ENSG00000124380homo_sapiensENSP0000024422792.258189.6774sphenodon_punctatusENSSPUP0000001139192.857190.2597
ENSG00000124380homo_sapiensENSP0000024422797.419492.2581crocodylus_porosusENSCPRP0000502369596.794991.6667
ENSG00000124380homo_sapiensENSP0000024422794.838788.3871laticauda_laticaudataENSLLTP0000000688796.078489.5425
ENSG00000124380homo_sapiensENSP0000024422794.193687.7419notechis_scutatusENSNSUP0000002859895.424888.8889
ENSG00000124380homo_sapiensENSP0000024422794.838788.3871pseudonaja_textilisENSPTXP0000002390796.078489.5425
ENSG00000124380homo_sapiensENSP0000024422793.548486.4516gallus_gallusENSGALP0001002780478.378472.4324
ENSG00000124380homo_sapiensENSP0000024422792.258184.5161meleagris_gallopavoENSMGAP0000000277184.615477.5148
ENSG00000124380homo_sapiensENSP0000024422756.774249.6774serinus_canariaENSSCAP0000002203570.461.6
ENSG00000124380homo_sapiensENSP0000024422769.677462.5806parus_majorENSPMJP0000002100358.064552.1505
ENSG00000124380homo_sapiensENSP0000024422793.548488.3871anolis_carolinensisENSACAP0000000585254.924251.8939
ENSG00000124380homo_sapiensENSP0000024422792.258182.5806neolamprologus_brichardiENSNBRP0000001266989.37580
ENSG00000124380homo_sapiensENSP0000024422794.838788.3871naja_najaENSNNAP0000000777596.078489.5425
ENSG00000124380homo_sapiensENSP0000024422772.258167.0968geospiza_fortisENSGFOP0000000832786.821780.6202
ENSG00000124380homo_sapiensENSP0000024422796.12989.0323taeniopygia_guttataENSTGUP0000000377096.12989.0323
ENSG00000124380homo_sapiensENSP0000024422790.322681.2903erpetoichthys_calabaricusENSECRP0000000037988.607679.7468
ENSG00000124380homo_sapiensENSP0000024422790.322680.6452kryptolebias_marmoratusENSKMAP0000001096486.956577.6398
ENSG00000124380homo_sapiensENSP0000024422796.12991.6129salvator_merianaeENSSMRP0000001992096.12991.6129
ENSG00000124380homo_sapiensENSP0000024422785.806470.9677oryzias_javanicusENSOJAP0000001093374.301761.4525
ENSG00000124380homo_sapiensENSP0000024422784.516173.5484amphilophus_citrinellusENSACIP0000001879381.366570.8075
ENSG00000124380homo_sapiensENSP0000024422789.032380amphiprion_perculaENSAPEP0000000384186.792477.9874
ENSG00000124380homo_sapiensENSP0000024422782.580666.4516oryzias_sinensisENSOSIP0000005049978.048862.8049
ENSG00000124380homo_sapiensENSP0000024422789.677483.2258pelodiscus_sinensisENSPSIP0000001851994.557887.7551
ENSG00000124380homo_sapiensENSP0000024422790.322680seriola_dumeriliENSSDUP0000000431186.956577.0186
ENSG00000124380homo_sapiensENSP0000024422787.096876.7742gasterosteus_aculeatusENSGACP0000001746787.096876.7742
ENSG00000124380homo_sapiensENSP0000024422789.677479.3548cynoglossus_semilaevisENSCSEP0000001536286.335476.3975
ENSG00000124380homo_sapiensENSP0000024422788.387179.3548poecilia_formosaENSPFOP0000002640584.049175.4601
ENSG00000124380homo_sapiensENSP0000024422791.612983.2258myripristis_murdjanENSMMDP0000505185288.198880.1242
ENSG00000124380homo_sapiensENSP0000024422784.516173.5484sander_luciopercaENSSLUP0000004052585.064974.026
ENSG00000124380homo_sapiensENSP0000024422796.12990.9677strigops_habroptilaENSSHBP0000500725595.512890.3846
ENSG00000124380homo_sapiensENSP0000024422789.677480.6452amphiprion_ocellarisENSAOCP0000000918786.335477.6398
ENSG00000124380homo_sapiensENSP0000024422793.548490.3226terrapene_carolina_triunguisENSTMTP0000000673092.948789.7436
ENSG00000124380homo_sapiensENSP0000024422790.967778.7097hucho_huchoENSHHUP0000002619688.12576.25
ENSG00000124380homo_sapiensENSP0000024422787.741974.1936hucho_huchoENSHHUP0000002616480.473468.0473
ENSG00000124380homo_sapiensENSP0000024422790.322681.9355betta_splendensENSBSLP0000001976586.956578.882
ENSG00000124380homo_sapiensENSP0000024422792.258180pygocentrus_nattereriENSPNAP0000000120391.666779.4872
ENSG00000124380homo_sapiensENSP0000024422790.322681.9355anabas_testudineusENSATEP0000002120486.956578.882
ENSG00000124380homo_sapiensENSP0000024422790.322680seriola_lalandi_dorsalisENSSLDP0000001882186.956577.0186
ENSG00000124380homo_sapiensENSP0000024422787.741978.0645labrus_bergyltaENSLBEP000000369498575.625
ENSG00000124380homo_sapiensENSP0000024422792.258181.9355pundamilia_nyerereiENSPNYP0000001144090.506380.3797
ENSG00000124380homo_sapiensENSP0000024422790.322679.3548mastacembelus_armatusENSMAMP0000003057586.956576.3975
ENSG00000124380homo_sapiensENSP0000024422789.677479.3548stegastes_partitusENSSPAP0000000612886.335476.3975
ENSG00000124380homo_sapiensENSP0000024422789.677480acanthochromis_polyacanthusENSAPOP0000002136086.335477.0186
ENSG00000124380homo_sapiensENSP0000024422790.967785.8064aquila_chrysaetos_chrysaetosENSACCP0002000919287.577682.6087
ENSG00000124380homo_sapiensENSP0000024422789.032381.2903cyprinodon_variegatusENSCVAP0000000122585.714378.2609
ENSG00000124380homo_sapiensENSP0000024422789.677480.6452denticeps_clupeoidesENSDCDP0000003166787.974779.1139
ENSG00000124380homo_sapiensENSP0000024422790.967781.9355larimichthys_croceaENSLCRP0000506352188.12579.375
ENSG00000124380homo_sapiensENSP0000024422789.032374.1936takifugu_rubripesENSTRUP0000003789287.341872.7848
ENSG00000124380homo_sapiensENSP0000024422792.903285.1613ficedula_albicollisENSFALP0000000012864.285758.9286
ENSG00000124380homo_sapiensENSP0000024422789.032378.0645hippocampus_comesENSHCOP0000001920589.032378.0645
ENSG00000124380homo_sapiensENSP0000024422772.258163.871coturnix_japonicaENSCJPP0000501399376.190567.3469
ENSG00000124380homo_sapiensENSP0000024422788.387179.3548poecilia_latipinnaENSPLAP0000002725385.093276.3975
ENSG00000124380homo_sapiensENSP0000024422747.741939.3548sinocyclocheilus_grahamiENSSGRP0000008604666.071454.4643
ENSG00000124380homo_sapiensENSP0000024422792.258181.9355maylandia_zebraENSMZEP0000500198890.506380.3797
ENSG00000124380homo_sapiensENSP0000024422790.967776.129tetraodon_nigroviridisENSTNIP0000001988889.240574.6835
ENSG00000124380homo_sapiensENSP0000024422790.967780.6452scleropages_formosusENSSFOP0001502852589.240579.1139
ENSG00000124380homo_sapiensENSP0000024422789.032382.5806leptobrachium_leishanenseENSLLEP0000000765286.2580
ENSG00000124380homo_sapiensENSP0000024422781.935576.7742scophthalmus_maximusENSSMAP0000003272781.410376.2821
ENSG00000124380homo_sapiensENSP0000024422777.419461.9355oryzias_melastigmaENSOMEP0000003407653.097342.4779

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000398involved_in mRNA splicing, via spliceosome1NASHomo_sapiens(9606)Process
GO:0003676enables nucleic acid binding1NASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005575is_active_in cellular_component1NDHomo_sapiens(9606)Component
GO:0005634located_in nucleus1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0008150involved_in biological_process1NDHomo_sapiens(9606)Process
GO:0046540part_of U4/U6 x U5 tri-snRNP complex1IPIHomo_sapiens(9606)Component

Expression