Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000124193 Gene ID 6431 Accession 10788
Symbol SRSF6 Alias B52;SFRS6;SRP55;HEL-S-91 Full Name serine and arginine rich splicing factor 6
Status Confidence Length 8154 bases Strand Plus strand
Position 20 : 43457893 - 43466046 RNA binding domain RRM_1
Summary The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000499492 RRM_1 PF00076 6.1e-33 1
ENSP00000499492 RRM_1 PF00076 6.1e-33 2
ENSP00000499517 RRM_1 PF00076 1.1e-32 1
ENSP00000499517 RRM_1 PF00076 1.1e-32 2
ENSP00000499666 RRM_1 PF00076 1.2e-32 1
ENSP00000499666 RRM_1 PF00076 1.2e-32 2
ENSP00000244020 RRM_1 PF00076 2.3e-32 1
ENSP00000244020 RRM_1 PF00076 2.3e-32 2
ENSP00000433544 RRM_1 PF00076 7e-17 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32949230 A putative frameshift variant in the CHM gene is associated with an unexpected splicing alteration in a choroideremia patient. Tiziana Fioretti 2020-11-01 Molecular genetics & genomic medicine
33376132 The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells. Inês Maria Alvelos 2021-03-01 Life science alliance
33905374 Splicing factor SRSF6 mediates pleural fibrosis. Li-Mei Liang 2021-05-24 JCI insight
34917618 Targeting Splicing Factor SRSF6 for Cancer Therapy. Wenting She 2021-01-01 Frontiers in cell and developmental biology
35454897 SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence. Namjeong Choi 2022-04-14 Cancers
30262848 Regulatory mechanisms of incomplete huntingtin mRNA splicing. Andreas Neueder 2018-09-27 Nature communications
34301951 Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Masahiko Ajiro 2021-07-23 Nature communications
33397371 LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM. Feifei Zhang 2021-01-04 Molecular cancer
35947702 Modeling splicing outcome by combining 5'ss strength and splicing regulatory elements. Lisa Müller 2022-08-26 Nucleic acids research
29114070 SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer. Ledong Wan 2019-01-01 Gut
28276498 The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells. Jung-Chun Lin 2017-03-09 Scientific reports
33050987 Relative strength of 5' splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA. Namjeong Choi 2021-03-01 BMB reports
25056543 BRCA1 EXON 11, a CERES (composite regulatory element of splicing) element involved in splice regulation. Claudia Tammaro 2014-07-23 International journal of molecular sciences
25889056 Balanced splicing at the Tat-specific HIV-1 3'ss A3 is critical for HIV-1 replication. Steffen Erkelenz 2015-03-28 Retrovirology

Transcripts

Name Transcript ID bp Protein Translation ID
SRSF6-204 ENST00000668808 1227 276aa ENSP00000499517
SRSF6-205 ENST00000670741 1077 226aa ENSP00000499492
SRSF6-203 ENST00000662078 1007 273aa ENSP00000499666
SRSF6-201 ENST00000244020 4353 344aa ENSP00000244020
SRSF6-202 ENST00000483871 1680 135aa ENSP00000433544
SRSF6-206 ENST00000671022 1275 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
59247Taste Perception1.3930000E-005-
85103Rest5E-627126917
105432Serologic Tests5E-825758998
105433Chlamydial Pneumonia5E-825758998

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124193homo_sapiensENSP0000045108874.264764.7059homo_sapiensENSP0000024402058.720951.1628
ENSG00000124193homo_sapiensENSP0000024318932.413818.9655homo_sapiensENSP0000024402027.325615.9884
ENSG00000124193homo_sapiensENSP0000036290054.858348.1781homo_sapiensENSP0000024402078.779169.186
ENSG00000124193homo_sapiensENSP0000025896259.274247.9839homo_sapiensENSP0000024402042.732634.593
ENSG00000124193homo_sapiensENSP0000022939056.108642.5339homo_sapiensENSP0000024402036.046527.3256
ENSG00000124193homo_sapiensENSP0000033018828.34117.5115homo_sapiensENSP0000024402035.755822.093
ENSG00000124193homo_sapiensENSP0000032590553.781544.958homo_sapiensENSP0000024402037.209331.1047
ENSG00000124193homo_sapiensENSP0000036282059.146350homo_sapiensENSP0000024402028.197723.8372

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124193homo_sapiensENSP00000244020100100nomascus_leucogenysENSNLEP00000007938100100
ENSG00000124193homo_sapiensENSP0000024402099.709399.7093pan_paniscusENSPPAP00000022318100100
ENSG00000124193homo_sapiensENSP00000244020100100pongo_abeliiENSPPYP00000012307100100
ENSG00000124193homo_sapiensENSP0000024402099.709399.7093pan_troglodytesENSPTRP0000007322999.709399.7093
ENSG00000124193homo_sapiensENSP00000244020100100gorilla_gorillaENSGGOP00000009578100100
ENSG00000124193homo_sapiensENSP0000024402091.569888.9535ornithorhynchus_anatinusENSOANP0000001426290.778188.1844
ENSG00000124193homo_sapiensENSP0000024402090.116388.3721sarcophilus_harrisiiENSSHAP0000001500690.116388.3721
ENSG00000124193homo_sapiensENSP0000024402080.523378.4884notamacropus_eugeniiENSMEUP0000001334091.118488.8158
ENSG00000124193homo_sapiensENSP0000024402083.720983.7209choloepus_hoffmanniENSCHOP0000000049983.478383.4783
ENSG00000124193homo_sapiensENSP0000024402096.511696.2209dasypus_novemcinctusENSDNOP0000000650695.953895.6647
ENSG00000124193homo_sapiensENSP0000024402060.755859.593erinaceus_europaeusENSEEUP0000000211395.871694.0367
ENSG00000124193homo_sapiensENSP0000024402094.476793.0233echinops_telfairiENSETEP0000000504694.752293.2945
ENSG00000124193homo_sapiensENSP0000024402099.127999.1279callithrix_jacchusENSCJAP0000005931199.127999.1279
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186cercocebus_atysENSCATP0000001334799.708599.7085
ENSG00000124193homo_sapiensENSP0000024402098.546598.5465macaca_fascicularisENSMFAP0000004641099.705999.7059
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186macaca_mulattaENSMMUP0000003794899.708599.7085
ENSG00000124193homo_sapiensENSP0000024402098.546597.9651macaca_nemestrinaENSMNEP0000002957298.833898.2507
ENSG00000124193homo_sapiensENSP0000024402099.418698.8372macaca_nemestrinaENSMNEP0000000643999.708599.1254
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186papio_anubisENSPANP0000005454799.708599.7085
ENSG00000124193homo_sapiensENSP0000024402061.918661.9186mandrillus_leucophaeusENSMLEP0000001471799.532799.5327
ENSG00000124193homo_sapiensENSP0000024402073.255872.3837tursiops_truncatusENSTTRP0000001460397.297396.139
ENSG00000124193homo_sapiensENSP0000024402020.348817.7326vulpes_vulpesENSVVUP0000002626155.118148.0315
ENSG00000124193homo_sapiensENSP0000024402056.68655.5233vulpes_vulpesENSVVUP0000002625291.981190.0943
ENSG00000124193homo_sapiensENSP0000024402097.674496.2209mus_spretusMGP_SPRETEiJ_P005808899.11597.6401
ENSG00000124193homo_sapiensENSP0000024402098.255897.093equus_asinusENSEASP0000506213098.255897.093
ENSG00000124193homo_sapiensENSP0000024402098.837297.9651capra_hircusENSCHIP0000001513398.550797.6812
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837capra_hircusENSCHIP0000000500398.260997.1014
ENSG00000124193homo_sapiensENSP0000024402072.09371.2209loxodonta_africanaENSLAFP0000002429595.019293.8697
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744panthera_leoENSPLOP0000000487798.546597.6744
ENSG00000124193homo_sapiensENSP0000024402079.941976.7442ailuropoda_melanoleucaENSAMEP0000000392262.642460.1367
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837bos_indicus_hybridENSBIXP0000500908298.260997.1014
ENSG00000124193homo_sapiensENSP0000024402061.046560.7558oryctolagus_cuniculusENSOCUP0000000842997.674497.2093
ENSG00000124193homo_sapiensENSP0000024402098.255897.093equus_caballusENSECAP0000004360498.255897.093
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744canis_lupus_familiarisENSCAFP0084501780098.546597.6744
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744panthera_pardusENSPPRP0000001672898.546597.6744
ENSG00000124193homo_sapiensENSP0000024402061.627960.7558marmota_marmota_marmotaENSMMMP0000001564099.530598.1221
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837marmota_marmota_marmotaENSMMMP0000002467799.122897.9532
ENSG00000124193homo_sapiensENSP0000024402098.255897.3837balaenoptera_musculusENSBMSP0001002526497.97197.1014
ENSG00000124193homo_sapiensENSP000002440205045.9302balaenoptera_musculusENSBMSP0001002169576.785770.5357
ENSG00000124193homo_sapiensENSP0000024402085.755884.593cavia_porcellusENSCPOP0000001057792.767391.5094
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744felis_catusENSFCAP0000002605098.546597.6744
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744ursus_americanusENSUAMP0000000386298.546597.6744
ENSG00000124193homo_sapiensENSP0000024402084.011681.3953monodelphis_domesticaENSMODP0000004963582.571480
ENSG00000124193homo_sapiensENSP0000024402092.151290.9884bison_bison_bisonENSBBBP0000002187487.811686.7036
ENSG00000124193homo_sapiensENSP0000024402098.255897.3837monodon_monocerosENSMMNP0001500221597.97197.1014
ENSG00000124193homo_sapiensENSP0000024402098.546597.093sus_scrofaENSSSCP0000003208198.260996.8116
ENSG00000124193homo_sapiensENSP0000024402098.837298.2558microcebus_murinusENSMICP0000004967298.550797.971
ENSG00000124193homo_sapiensENSP0000024402028.488426.4535octodon_degusENSODEP0000002249972.592667.4074
ENSG00000124193homo_sapiensENSP0000024402059.59358.4302jaculus_jaculusENSJJAP0000001983498.086196.1722
ENSG00000124193homo_sapiensENSP0000024402098.837297.9651ovis_aries_rambouilletENSOARP0002002137298.550797.6812
ENSG00000124193homo_sapiensENSP0000024402061.046560.7558ursus_maritimusENSUMAP0000000117797.674497.2093
ENSG00000124193homo_sapiensENSP0000024402073.255872.9651ochotona_princepsENSOPRP0000000184697.674497.2868
ENSG00000124193homo_sapiensENSP0000024402091.860588.6628delphinapterus_leucasENSDLEP0000000359881.865379.0155
ENSG00000124193homo_sapiensENSP0000024402098.255897.3837physeter_catodonENSPCTP0000502797897.97197.1014
ENSG00000124193homo_sapiensENSP0000024402064.825657.8488physeter_catodonENSPCTP0000502794676.369968.1507
ENSG00000124193homo_sapiensENSP0000024402097.674495.9302mus_caroliMGP_CAROLIEiJ_P005592499.11597.3451
ENSG00000124193homo_sapiensENSP0000024402097.674496.2209mus_musculusENSMUSP0000011906599.11597.6401
ENSG00000124193homo_sapiensENSP0000024402098.837298.2558dipodomys_ordiiENSDORP0000002438698.837298.2558
ENSG00000124193homo_sapiensENSP0000024402082.267481.686mustela_putorius_furoENSMPUP0000001758098.263997.5694
ENSG00000124193homo_sapiensENSP0000024402099.127999.1279aotus_nancymaaeENSANAP0000001229199.127999.1279
ENSG00000124193homo_sapiensENSP0000024402099.418699.1279saimiri_boliviensis_boliviensisENSSBOP0000003510799.418699.1279
ENSG00000124193homo_sapiensENSP0000024402069.767466.8605saimiri_boliviensis_boliviensisENSSBOP0000003587075.709872.5552
ENSG00000124193homo_sapiensENSP0000024402080.523379.6512vicugna_pacosENSVPAP0000000278780.289979.4203
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186chlorocebus_sabaeusENSCSAP0000001016199.708599.7085
ENSG00000124193homo_sapiensENSP0000024402086.918685.7558tupaia_belangeriENSTBEP0000001164795.527294.2492
ENSG00000124193homo_sapiensENSP0000024402028.197725.8721mesocricetus_auratusENSMAUP0000002131271.851965.9259
ENSG00000124193homo_sapiensENSP0000024402066.279162.5phocoena_sinusENSPSNP0000001447980.281775.7042
ENSG00000124193homo_sapiensENSP0000024402098.255897.3837phocoena_sinusENSPSNP0000002978397.97197.1014
ENSG00000124193homo_sapiensENSP0000024402098.255897.3837camelus_dromedariusENSCDRP0000501690597.97197.1014
ENSG00000124193homo_sapiensENSP0000024402083.720983.1395carlito_syrichtaENSTSYP0000001797597.959297.2789
ENSG00000124193homo_sapiensENSP0000024402061.046560.7558panthera_tigris_altaicaENSPTIP0000002229497.674497.2093
ENSG00000124193homo_sapiensENSP0000024402097.674496.2209rattus_norvegicusENSRNOP0000000842799.11597.6401
ENSG00000124193homo_sapiensENSP0000024402098.546598.2558prolemur_simusENSPSMP0000000049698.546598.2558
ENSG00000124193homo_sapiensENSP0000024402060.465159.8837microtus_ochrogasterENSMOCP0000002135199.047698.0952
ENSG00000124193homo_sapiensENSP0000024402072.965172.093sorex_araneusENSSARP0000000144498.046996.875
ENSG00000124193homo_sapiensENSP0000024402092.441988.9535peromyscus_maniculatus_bairdiiENSPEMP0000003277093.255189.7361
ENSG00000124193homo_sapiensENSP0000024402095.348893.8953bos_mutusENSBMUP0000001815096.470695
ENSG00000124193homo_sapiensENSP0000024402097.674496.2209mus_spicilegusENSMSIP0000003412199.11597.6401
ENSG00000124193homo_sapiensENSP0000024402097.674496.8023cricetulus_griseus_chok1gshdENSCGRP0000102439499.11598.2301
ENSG00000124193homo_sapiensENSP0000024402094.767492.7326pteropus_vampyrusENSPVAP0000001435695.043793.0029
ENSG00000124193homo_sapiensENSP0000024402085.755881.686myotis_lucifugusENSMLUP0000001514485.507281.4493
ENSG00000124193homo_sapiensENSP0000024402089.825688.0814vombatus_ursinusENSVURP0001002560890.615888.8563
ENSG00000124193homo_sapiensENSP0000024402095.348893.8953rhinolophus_ferrumequinumENSRFEP0001001132195.072593.6232
ENSG00000124193homo_sapiensENSP0000024402060.755860.4651neovison_visonENSNVIP0000001556797.209396.7442
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837bos_taurusENSBTAP0000001124098.260997.1014
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837heterocephalus_glaber_femaleENSHGLP0000004793098.833897.6676
ENSG00000124193homo_sapiensENSP0000024402097.674497.6744rhinopithecus_bietiENSRBIP0000003556899.408399.4083
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744canis_lupus_dingoENSCAFP0002001693498.546597.6744
ENSG00000124193homo_sapiensENSP0000024402098.837298.5465sciurus_vulgarisENSSVLP0000502946599.415299.1228
ENSG00000124193homo_sapiensENSP0000024402089.825688.0814phascolarctos_cinereusENSPCIP0000000461690.615888.8563
ENSG00000124193homo_sapiensENSP0000024402088.953586.0465procavia_capensisENSPCAP0000001023892.168789.1566
ENSG00000124193homo_sapiensENSP0000024402097.09396.2209nannospalax_galiliENSNGAP0000001700899.701598.806
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837bos_grunniensENSBGRP0000001872398.260997.1014
ENSG00000124193homo_sapiensENSP0000024402098.546597.3837chinchilla_lanigeraENSCLAP0000001486098.833897.6676
ENSG00000124193homo_sapiensENSP0000024402088.662887.7907cervus_hanglu_yarkandensisENSCHYP0000003717297.756496.7949
ENSG00000124193homo_sapiensENSP0000024402098.546597.093catagonus_wagneriENSCWAP0000000873898.260996.8116
ENSG00000124193homo_sapiensENSP0000024402098.837298.2558ictidomys_tridecemlineatusENSSTOP0000000974999.415298.8304
ENSG00000124193homo_sapiensENSP0000024402097.965197.093otolemur_garnettiiENSOGAP0000001296597.681296.8116
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186cebus_imitatorENSCCAP0000001645499.418699.4186
ENSG00000124193homo_sapiensENSP0000024402071.802368.8953cebus_imitatorENSCCAP0000000355084.879781.4433
ENSG00000124193homo_sapiensENSP0000024402072.674468.8953urocitellus_parryiiENSUPAP0001000062979.617875.4777
ENSG00000124193homo_sapiensENSP0000024402098.546597.6744moschus_moschiferusENSMMSP0000002696698.260997.3913
ENSG00000124193homo_sapiensENSP0000024402099.418699.4186rhinopithecus_roxellanaENSRROP0000001127799.708599.7085
ENSG00000124193homo_sapiensENSP0000024402097.674495.9302mus_pahariMGP_PahariEiJ_P006690999.11597.3451
ENSG00000124193homo_sapiensENSP0000024402098.837298.5465propithecus_coquereliENSPCOP0000002765998.550798.2609
ENSG00000124193homo_sapiensENSP0000024402073.255865.9884callorhinchus_miliiENSCMIP0000003785968.664861.8529
ENSG00000124193homo_sapiensENSP0000024402081.395377.6163latimeria_chalumnaeENSLACP0000000616182.840278.9941
ENSG00000124193homo_sapiensENSP0000024402072.09362.7907lepisosteus_oculatusENSLOCP0000000502052.542445.7627
ENSG00000124193homo_sapiensENSP0000024402080.523371.8023clupea_harengusENSCHAP0000004692776.731368.4211
ENSG00000124193homo_sapiensENSP0000024402044.767438.9535clupea_harengusENSCHAP0000006058166.379357.7586
ENSG00000124193homo_sapiensENSP0000024402026.162823.5465clupea_harengusENSCHAP0000006057988.235379.4118
ENSG00000124193homo_sapiensENSP0000024402079.651271.8023danio_rerioENSDARP0000002208977.183169.5775
ENSG00000124193homo_sapiensENSP0000024402073.546566.2791danio_rerioENSDARP0000009452272.910765.7061
ENSG00000124193homo_sapiensENSP0000024402077.90769.7674carassius_auratusENSCARP0000005803182.71674.0741
ENSG00000124193homo_sapiensENSP0000024402077.616371.2209carassius_auratusENSCARP0000003311274.58168.4358
ENSG00000124193homo_sapiensENSP0000024402073.837265.1163carassius_auratusENSCARP0000006749075.370966.4688
ENSG00000124193homo_sapiensENSP0000024402081.395375carassius_auratusENSCARP000001187758073.7143
ENSG00000124193homo_sapiensENSP0000024402079.941972.6744astyanax_mexicanusENSAMXP0000000317173.138366.4894
ENSG00000124193homo_sapiensENSP0000024402079.651271.2209astyanax_mexicanusENSAMXP0000004037380.82672.2714
ENSG00000124193homo_sapiensENSP0000024402069.767463.3721ictalurus_punctatusENSIPUP0000000688184.805777.0318
ENSG00000124193homo_sapiensENSP0000024402074.709366.8605ictalurus_punctatusENSIPUP0000002494076.035568.0473
ENSG00000124193homo_sapiensENSP0000024402074.709367.7326esox_luciusENSELUP0000001322977.409670.1807
ENSG00000124193homo_sapiensENSP0000024402078.779169.7674esox_luciusENSELUP0000002544074.450565.9341
ENSG00000124193homo_sapiensENSP0000024402072.965166.8605electrophorus_electricusENSEEEP0000001813371.306865.3409
ENSG00000124193homo_sapiensENSP0000024402045.930240.1163electrophorus_electricusENSEEEP0000002281479.39769.3467
ENSG00000124193homo_sapiensENSP0000024402025.290723.2558electrophorus_electricusENSEEEP0000002281286.138679.2079
ENSG00000124193homo_sapiensENSP0000024402027.325623.5465oncorhynchus_kisutchENSOKIP0000505559984.684772.973
ENSG00000124193homo_sapiensENSP0000024402077.034968.314oncorhynchus_kisutchENSOKIP0000511680879.341370.3593
ENSG00000124193homo_sapiensENSP0000024402056.104750.2907oncorhynchus_kisutchENSOKIP0000505564774.517466.7954
ENSG00000124193homo_sapiensENSP0000024402047.674440.9884oncorhynchus_kisutchENSOKIP0000509252056.164448.2877
ENSG00000124193homo_sapiensENSP0000024402027.325623.5465oncorhynchus_mykissENSOMYP0000009600784.684772.973
ENSG00000124193homo_sapiensENSP0000024402076.744268.0233oncorhynchus_mykissENSOMYP0000009328579.041970.0599
ENSG00000124193homo_sapiensENSP0000024402052.325645.9302oncorhynchus_mykissENSOMYP0000014240864.981957.0397
ENSG00000124193homo_sapiensENSP0000024402056.104750oncorhynchus_mykissENSOMYP0000009601473.946465.9004
ENSG00000124193homo_sapiensENSP0000024402053.488448.8372salmo_salarENSSSAP0000003045173.895667.4699
ENSG00000124193homo_sapiensENSP0000024402053.197748.5465salmo_salarENSSSAP0000000966474.089167.6113
ENSG00000124193homo_sapiensENSP0000024402048.837240.407salmo_salarENSSSAP0000016068362.453551.6729
ENSG00000124193homo_sapiensENSP0000024402076.453569.186salmo_truttaENSSTUP0000002422578.507571.0448
ENSG00000124193homo_sapiensENSP0000024402076.744268.6047salmo_truttaENSSTUP0000010525079.041970.6587
ENSG00000124193homo_sapiensENSP0000024402023.837221.5116gadus_morhuaENSGMOP0000003209279.611671.8447
ENSG00000124193homo_sapiensENSP0000024402079.069871.5116fundulus_heteroclitusENSFHEP0000003503781.19473.4328
ENSG00000124193homo_sapiensENSP0000024402033.430231.1047poecilia_reticulataENSPREP0000000142377.181271.8121
ENSG00000124193homo_sapiensENSP0000024402078.197769.186xiphophorus_maculatusENSXMAP0000003719681.268971.9033
ENSG00000124193homo_sapiensENSP0000024402072.383764.5349oryzias_latipesENSORLP0000000439975.454567.2727
ENSG00000124193homo_sapiensENSP0000024402072.965166.5698cyclopterus_lumpusENSCLMP0000500145480.448773.3974
ENSG00000124193homo_sapiensENSP0000024402078.779169.7674oreochromis_niloticusENSONIP0000000241379.008769.9708
ENSG00000124193homo_sapiensENSP000002440202522.093oreochromis_niloticusENSONIP0000004803892.473181.7204
ENSG00000124193homo_sapiensENSP0000024402071.802363.9535haplochromis_burtoniENSHBUP0000000501778.913770.2875
ENSG00000124193homo_sapiensENSP0000024402024.418622.093astatotilapia_callipteraENSACLP0000003599088.421180
ENSG00000124193homo_sapiensENSP0000024402074.418666.8605sparus_aurataENSSAUP0001002916175.739668.0473
ENSG00000124193homo_sapiensENSP000002440202522.3837lates_calcariferENSLCAP0001001964867.187560.1562
ENSG00000124193homo_sapiensENSP0000024402080.523373.5465lates_calcariferENSLCAP0001000200679.369672.4928
ENSG00000124193homo_sapiensENSP0000024402081.68675.2907xenopus_tropicalisENSXETP0000010790349.471845.5986
ENSG00000124193homo_sapiensENSP0000024402089.244286.3372chrysemys_picta_belliiENSCPBP0000002560188.728385.8382
ENSG00000124193homo_sapiensENSP0000024402088.662885.4651sphenodon_punctatusENSSPUP0000000644289.442886.217
ENSG00000124193homo_sapiensENSP0000024402052.90750.5814crocodylus_porosusENSCPRP0000501958284.259380.5556
ENSG00000124193homo_sapiensENSP0000024402062.560.7558laticauda_laticaudataENSLLTP0000001472695.982193.3036
ENSG00000124193homo_sapiensENSP0000024402027.90726.1628notechis_scutatusENSNSUP0000000127181.355976.2712
ENSG00000124193homo_sapiensENSP0000024402060.465158.7209pseudonaja_textilisENSPTXP0000001099293.273590.583
ENSG00000124193homo_sapiensENSP0000024402090.40787.5anas_platyrhynchos_platyrhynchosENSAPLP0000001431889.367886.4943
ENSG00000124193homo_sapiensENSP0000024402089.825686.6279gallus_gallusENSGALP0001003676389.825686.6279
ENSG00000124193homo_sapiensENSP0000024402068.31466.2791meleagris_gallopavoENSMGAP0000000026773.208771.028
ENSG00000124193homo_sapiensENSP0000024402051.744248.2558serinus_canariaENSSCAP0000001470687.254981.3726
ENSG00000124193homo_sapiensENSP0000024402090.697787.7907parus_majorENSPMJP0000000236864.864962.7859
ENSG00000124193homo_sapiensENSP0000024402088.662884.3023anolis_carolinensisENSACAP0000000201987.392583.0946
ENSG00000124193homo_sapiensENSP0000024402074.127965.407neolamprologus_brichardiENSNBRP0000001907081.469771.885
ENSG00000124193homo_sapiensENSP0000024402080.81472.9651neolamprologus_brichardiENSNBRP0000000230277.437369.9164
ENSG00000124193homo_sapiensENSP0000024402060.465158.7209naja_najaENSNNAP0000000405593.273590.583
ENSG00000124193homo_sapiensENSP0000024402055.81453.4884geospiza_fortisENSGFOP0000000886488.479384.7926
ENSG00000124193homo_sapiensENSP0000024402090.697787.7907taeniopygia_guttataENSTGUP0000003025689.655286.7816
ENSG00000124193homo_sapiensENSP0000024402078.488471.2209erpetoichthys_calabaricusENSECRP0000001881976.271269.209
ENSG00000124193homo_sapiensENSP0000024402071.511664.8256kryptolebias_marmoratusENSKMAP0000001598685.416777.4306
ENSG00000124193homo_sapiensENSP0000024402088.081484.3023salvator_merianaeENSSMRP0000000079788.338284.5481
ENSG00000124193homo_sapiensENSP0000024402077.034968.8953oryzias_javanicusENSOJAP0000004954173.611165.8333
ENSG00000124193homo_sapiensENSP0000024402075.872167.7326amphilophus_citrinellusENSACIP0000003059181.308472.5857
ENSG00000124193homo_sapiensENSP0000024402072.383764.2442amphilophus_citrinellusENSACIP0000002605876.615468
ENSG00000124193homo_sapiensENSP0000024402071.220963.6628dicentrarchus_labraxENSDLAP0000503843174.018166.1631
ENSG00000124193homo_sapiensENSP0000024402078.197770.9302amphiprion_perculaENSAPEP0000001833577.298970.1149
ENSG00000124193homo_sapiensENSP0000024402065.697758.1395amphiprion_perculaENSAPEP0000002922179.858770.6714
ENSG00000124193homo_sapiensENSP0000024402024.418622.9651oryzias_sinensisENSOSIP0000002282988.421183.1579
ENSG00000124193homo_sapiensENSP0000024402024.418622.9651oryzias_sinensisENSOSIP0000000232088.421183.1579
ENSG00000124193homo_sapiensENSP0000024402088.953586.0465gopherus_evgoodeiENSGEVP0000501693788.439385.5491
ENSG00000124193homo_sapiensENSP0000024402089.534986.3372chelonoidis_abingdoniiENSCABP0000000110589.017385.8382
ENSG00000124193homo_sapiensENSP0000024402079.360572.9651seriola_dumeriliENSSDUP0000002212778.223571.9198
ENSG00000124193homo_sapiensENSP0000024402024.709322.6744seriola_dumeriliENSSDUP0000001511392.391384.7826
ENSG00000124193homo_sapiensENSP0000024402026.453524.1279cottoperca_gobioENSCGOP0000001526287.579.8077
ENSG00000124193homo_sapiensENSP0000024402044.767438.6628cottoperca_gobioENSCGOP0000001526666.956557.8261
ENSG00000124193homo_sapiensENSP0000024402082.558179.6512struthio_camelus_australisENSSCUP0000001528985.542282.5301
ENSG00000124193homo_sapiensENSP0000024402090.697788.0814anser_brachyrhynchusENSABRP0000000909789.655287.069
ENSG00000124193homo_sapiensENSP0000024402079.941969.186gasterosteus_aculeatusENSGACP0000000807769.79760.4061
ENSG00000124193homo_sapiensENSP0000024402033.430231.3953cynoglossus_semilaevisENSCSEP0000003088586.466281.203
ENSG00000124193homo_sapiensENSP0000024402044.476739.8256cynoglossus_semilaevisENSCSEP0000003089264.285757.563
ENSG00000124193homo_sapiensENSP0000024402081.395373.8372poecilia_formosaENSPFOP0000000640573.490866.6667
ENSG00000124193homo_sapiensENSP0000024402024.418622.093myripristis_murdjanENSMMDP0000503740995.454586.3636
ENSG00000124193homo_sapiensENSP0000024402072.09363.6628myripristis_murdjanENSMMDP0000501252768.319660.3306
ENSG00000124193homo_sapiensENSP0000024402078.488470.9302sander_luciopercaENSSLUP0000001062575.41968.1564
ENSG00000124193homo_sapiensENSP0000024402090.697788.0814strigops_habroptilaENSSHBP0000500778889.655287.069
ENSG00000124193homo_sapiensENSP0000024402074.127965.9884amphiprion_ocellarisENSAOCP0000000133580.696271.8354
ENSG00000124193homo_sapiensENSP0000024402047.09340.407amphiprion_ocellarisENSAOCP0000002923767.557.9167
ENSG00000124193homo_sapiensENSP0000024402027.034924.4186amphiprion_ocellarisENSAOCP0000001471681.578973.6842
ENSG00000124193homo_sapiensENSP0000024402089.244286.3372terrapene_carolina_triunguisENSTMTP0000002412688.728385.8382
ENSG00000124193homo_sapiensENSP0000024402024.418621.5116hucho_huchoENSHHUP0000001201674.336365.4867
ENSG00000124193homo_sapiensENSP0000024402078.488470.3488betta_splendensENSBSLP0000000673876.923168.9459
ENSG00000124193homo_sapiensENSP0000024402033.430232.2674pygocentrus_nattereriENSPNAP0000003410088.461585.3846
ENSG00000124193homo_sapiensENSP0000024402046.802341.8605pygocentrus_nattereriENSPNAP0000000769268.803461.5385
ENSG00000124193homo_sapiensENSP0000024402045.930240.407pygocentrus_nattereriENSPNAP0000001695965.020657.2016
ENSG00000124193homo_sapiensENSP0000024402078.488470.3488anabas_testudineusENSATEP0000001045684.37575.625
ENSG00000124193homo_sapiensENSP0000024402024.709321.8023anabas_testudineusENSATEP0000004134191.397980.6452
ENSG00000124193homo_sapiensENSP0000024402080.232673.2558seriola_lalandi_dorsalisENSSLDP0000002966679.538972.6225
ENSG00000124193homo_sapiensENSP0000024402024.709322.6744seriola_lalandi_dorsalisENSSLDP0000001891092.391384.7826
ENSG00000124193homo_sapiensENSP0000024402077.90770.3488labrus_bergyltaENSLBEP0000000950374.651867.4095
ENSG00000124193homo_sapiensENSP0000024402072.09363.9535pundamilia_nyerereiENSPNYP0000000643979.233270.2875
ENSG00000124193homo_sapiensENSP0000024402081.395372.3837pundamilia_nyerereiENSPNYP0000001486676.712368.2192
ENSG00000124193homo_sapiensENSP0000024402061.918656.1047mastacembelus_armatusENSMAMP0000004207983.203175.3906
ENSG00000124193homo_sapiensENSP0000024402081.104774.4186mastacembelus_armatusENSMAMP0000002557179.942773.3524
ENSG00000124193homo_sapiensENSP0000024402080.232672.093stegastes_partitusENSSPAP0000000324175.616467.9452
ENSG00000124193homo_sapiensENSP0000024402025.290722.3837stegastes_partitusENSSPAP0000002913290.62580.2083
ENSG00000124193homo_sapiensENSP0000024402055.81449.4186oncorhynchus_tshawytschaENSOTSP0000502360372.180563.9098
ENSG00000124193homo_sapiensENSP0000024402026.744222.9651oncorhynchus_tshawytschaENSOTSP0000502360182.882971.1712
ENSG00000124193homo_sapiensENSP0000024402052.90745.0581oncorhynchus_tshawytschaENSOTSP0000502312458.14749.5208
ENSG00000124193homo_sapiensENSP0000024402077.034968.314oncorhynchus_tshawytschaENSOTSP0000510076879.341370.3593
ENSG00000124193homo_sapiensENSP0000024402046.511639.8256acanthochromis_polyacanthusENSAPOP0000001383168.085158.2979
ENSG00000124193homo_sapiensENSP0000024402036.627933.4302acanthochromis_polyacanthusENSAPOP0000001379578.260971.4286
ENSG00000124193homo_sapiensENSP0000024402090.697788.0814aquila_chrysaetos_chrysaetosENSACCP0002000455689.655287.069
ENSG00000124193homo_sapiensENSP0000024402059.011655.814nothobranchius_furzeriENSNFUP0001502897389.82384.9557
ENSG00000124193homo_sapiensENSP0000024402033.430231.9767cyprinodon_variegatusENSCVAP0000000090988.461584.6154
ENSG00000124193homo_sapiensENSP0000024402044.18638.3721cyprinodon_variegatusENSCVAP0000002045558.237550.5747
ENSG00000124193homo_sapiensENSP0000024402079.360572.3837denticeps_clupeoidesENSDCDP0000004744878.674471.7579
ENSG00000124193homo_sapiensENSP0000024402072.09366.2791larimichthys_croceaENSLCRP0000502905874.251568.2635
ENSG00000124193homo_sapiensENSP0000024402077.325669.4767takifugu_rubripesENSTRUP0000005871175.141267.5141
ENSG00000124193homo_sapiensENSP0000024402072.383767.7326ficedula_albicollisENSFALP0000002673080.844275.6494
ENSG00000124193homo_sapiensENSP0000024402074.709365.1163hippocampus_comesENSHCOP0000001830082.371871.7949
ENSG00000124193homo_sapiensENSP0000024402072.674465.9884cyprinus_carpio_carpioENSCCRP0000011120973.313866.5689
ENSG00000124193homo_sapiensENSP0000024402079.651270.3488cyprinus_carpio_carpioENSCCRP0000010973583.536673.7805
ENSG00000124193homo_sapiensENSP0000024402080.81474.1279cyprinus_carpio_carpioENSCCRP0000012973777.653671.229
ENSG00000124193homo_sapiensENSP0000024402079.360570.9302cyprinus_carpio_carpioENSCCRP0000012827177.556869.3182
ENSG00000124193homo_sapiensENSP0000024402089.534986.6279coturnix_japonicaENSCJPP0000502487889.017386.1272
ENSG00000124193homo_sapiensENSP0000024402078.488469.186poecilia_latipinnaENSPLAP0000000692476.056367.0423
ENSG00000124193homo_sapiensENSP0000024402073.546564.8256sinocyclocheilus_grahamiENSSGRP0000008035070.083161.7729
ENSG00000124193homo_sapiensENSP0000024402056.104749.4186sinocyclocheilus_grahamiENSSGRP0000005145274.230865.3846
ENSG00000124193homo_sapiensENSP0000024402068.604761.0465sinocyclocheilus_grahamiENSSGRP0000009372274.683566.4557
ENSG00000124193homo_sapiensENSP0000024402080.523371.8023sinocyclocheilus_grahamiENSSGRP0000003792581.710972.8614
ENSG00000124193homo_sapiensENSP0000024402074.127965.6977maylandia_zebraENSMZEP0000501067980.696271.519
ENSG00000124193homo_sapiensENSP0000024402070.639563.0814maylandia_zebraENSMZEP0000502770784.66975.6098
ENSG00000124193homo_sapiensENSP0000024402075.872169.186tetraodon_nigroviridisENSTNIP0000000231179.573272.561
ENSG00000124193homo_sapiensENSP0000024402073.837266.5698paramormyrops_kingsleyaeENSPKIP0000001150669.972563.0854
ENSG00000124193homo_sapiensENSP0000024402035.755832.8488paramormyrops_kingsleyaeENSPKIP0000003741087.857180.7143
ENSG00000124193homo_sapiensENSP0000024402044.767438.9535paramormyrops_kingsleyaeENSPKIP0000003742663.636455.3719
ENSG00000124193homo_sapiensENSP0000024402079.941972.9651scleropages_formosusENSSFOP0001503069773.924767.4731
ENSG00000124193homo_sapiensENSP0000024402045.639539.8256scleropages_formosusENSSFOP0001502364365.966457.563
ENSG00000124193homo_sapiensENSP0000024402026.162822.9651scleropages_formosusENSSFOP0001503168287.378676.699
ENSG00000124193homo_sapiensENSP0000024402084.59377.0349leptobrachium_leishanenseENSLLEP0000004893965.540559.6847
ENSG00000124193homo_sapiensENSP0000024402067.441957.5581scophthalmus_maximusENSSMAP0000002856246.49339.6794
ENSG00000124193homo_sapiensENSP0000024402078.197770.3488scophthalmus_maximusENSSMAP0000002427673.901166.4835
ENSG00000124193homo_sapiensENSP0000024402073.546564.2442oryzias_melastigmaENSOMEP0000000500873.976664.6199

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000380involved_in alternative mRNA splicing, via spliceosome1IDAHomo_sapiens(9606)Process
GO:0000381acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome2IDA,IMPHomo_sapiens(9606)Process
GO:0000398involved_in mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding3HDA,IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0006376involved_in mRNA splice site recognition1IMPHomo_sapiens(9606)Process
GO:0010837involved_in regulation of keratinocyte proliferation1IMPHomo_sapiens(9606)Process
GO:0016607is_active_in nuclear speck2IBA,IDAHomo_sapiens(9606)Component
GO:0032868involved_in response to insulin1IEAHomo_sapiens(9606)Process
GO:0036002enables pre-mRNA binding1IDAHomo_sapiens(9606)Function
GO:0045617involved_in negative regulation of keratinocyte differentiation1IMPHomo_sapiens(9606)Process
GO:0048025involved_in negative regulation of mRNA splicing, via spliceosome1IDAHomo_sapiens(9606)Process
GO:0060501acts_upstream_of_or_within positive regulation of epithelial cell proliferation involved in lung morphogenesis1IDAHomo_sapiens(9606)Process
GO:0061041involved_in regulation of wound healing1IMPHomo_sapiens(9606)Process
GO:2000675involved_in negative regulation of type B pancreatic cell apoptotic process1IEAHomo_sapiens(9606)Process

Expression