Ensembl ID ENSG00000124193 Gene ID 6431 Accession 10788
Gene Symbol SRSF6 Alias B52;SFRS6;SRP55;HEL-S-91 Full Name serine and arginine rich splicing factor 6
Position 20 : 43457893 - 43466046 Length 8154 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

ENSG00000124193 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124193 SRSF6 0.47 2.51e-11 COAD
ENSG00000124193 SRSF6 0.52 8.12e-20 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124193 SRSF6 AML 22722453
ENSG00000124193 SRSF6 colon cancers 23132731
ENSG00000124193 SRSF6 skin cancer 24440982
ENSG00000124193 SRSF6 cancers 24572810
ENSG00000124193 SRSF6 cancers 27282379
ENSG00000124193 SRSF6 colorectal cancer 27443606
ENSG00000124193 SRSF6 cancer 28276498
ENSG00000124193 SRSF6 HNSCC 28843252
ENSG00000124193 SRSF6 colorectal cancer 29114070
ENSG00000124193 SRSF6 colorectal cancer 29416704
ENSG00000124193 SRSF6 breast cancer 31729134
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124193 SRSF6 MESO 0.0026 low
ENSG00000124193 SRSF6 STAD 0.01 low
ENSG00000124193 SRSF6 UVM 0.026 high
ENSG00000124193 SRSF6 PAAD 0.00099 low
ENSG00000124193 SRSF6 UCEC 0.03 high
ENSG00000124193 SRSF6 ACC 0.011 high
ENSG00000124193 SRSF6 LGG 0.0018 low
ENSG00000124193 SRSF6 HNSC 0.044 low
ENSG00000124193 SRSF6 READ 0.012 low
ENSG00000124193 SRSF6 KICH 0.028 high
ENSG00000124193 SRSF6 LUAD 0.0054 low
ENSG00000124193 SRSF6 PCPG 0.039 high
ENSG00000124193 SRSF6 THYM 0.0041 low
ENSG00000124193 SRSF6 OV 0.032 high
ENSG00000124193 SRSF6 KIRC 0.012 high
ENSG00000124193 SRSF6 PRAD 0.0026 high
ENSG00000124193 SRSF6 BLCA 0.013 low
ENSG00000124193 SRSF6 LAML 0.013 low
ENSG00000124193 SRSF6 SKCM 0.0011 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124193 SRSF6 READ Amp 1.656501 0.173576 1.329944 0.890909
ENSG00000124193 SRSF6 COAD Amp 7.812554 0.181714 1.228219 0.720621
ENSG00000124193 SRSF6 BLCA Amp 2.092506 0.212389 0.568904 0.607843
ENSG00000124193 SRSF6 STAD Amp 1.940132 0.168396 0.705159 0.653061