Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2SINVVEEVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_236 DataSet_01_93

Description

Ensembl ID ENSG00000116560 Gene ID 6421 Accession 10774
Symbol SFPQ Alias PSF;POMP100;PPP1R140 Full Name splicing factor proline and glutamine rich
Status Confidence Length 17069 bases Strand Minus strand
Position 1 : 35176378 - 35193446 RNA binding domain RRM_1
Summary Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000349748 RRM_1 PF00076 1.8e-29 1
ENSP00000349748 RRM_1 PF00076 1.8e-29 2
ENSP00000512713 RRM_1 PF00076 1.9e-29 1
ENSP00000512713 RRM_1 PF00076 1.9e-29 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35053294 The Role of the lncRNA MALAT1 in Neuroprotection against Hypoxic/Ischemic Injury. Liping Wang 2022-01-17 Biomolecules
36467404 The roles of lncRNA functions and regulatory mechanisms in the diagnosis and treatment of hepatocellular carcinoma. Yuling Hong 2022-01-01 Frontiers in cell and developmental biology
35822056 Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA. Kaoru Sato 2021-01-01 Frontiers in aging
31204691 A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ. Welwelwela Thushara Hewage 2019-06-01 Acta crystallographica. Section F, Structural biology communications
35547764 mTOR regulates aerobic glycolysis through NEAT1 and nuclear paraspeckle-mediated mechanism in hepatocellular carcinoma. Hong Zhang 2022-01-01 Theranostics
37388923 Identification of small-molecule inhibitors against the interaction of RNA-binding protein PSF and its target RNA for cancer treatment. Ken-Ichi Takayama 2023-06-01 PNAS nexus
32998269 The Emerging Role of the RNA-Binding Protein SFPQ in Neuronal Function and Neurodegeneration. Wa Yee Lim 2020-09-28 International journal of molecular sciences
31447650 Axonal Transport and Mitochondrial Function in Neurons. Amrita Mandal 2019-01-01 Frontiers in cellular neuroscience
22114566 The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. Sara Landeras-Bueno 2011-11-01 PLoS pathogens
23642268 Proteomic analyses and identification of arginine methylated proteins differentially recognized by autosera from anti-Sm positive SLE patients. Hong-How Chang 2013-05-04 Journal of biomedical science
28392072 Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development. Swapna Thomas-Jinu 2017-04-19 Neuron
29084942 Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq. Silvia Bottini 2017-10-30 Nature communications
35662392 Condensates induced by transcription inhibition localize active chromatin to nucleoli. Takaaki Yasuhara 2022-08-04 Molecular cell
31655860 The RNA-RNA base pairing potential of human Dicer and Ago2 proteins. Maria Pokornowska 2020-08-01 Cellular and molecular life sciences : CMLS
35075799 LncRNA-422 suppresses the proliferation and growth of colorectal cancer cells by targeting SFPQ. Yixuan Meng 2022-01-01 Clinical and translational medicine
36177382 SFPQ promotes RAS-mutant cancer cell growth by modulating 5'-UTR mediated translational control of CK1α. Tong Jing Venetia Kok 2022-09-01 NAR cancer
31981477 SFPQ Is an FTO-Binding Protein that Facilitates the Demethylation Substrate Preference. Haiping Song 2020-03-19 Cell chemical biology
28894257 Stress Granules Contain Rbfox2 with Cell Cycle-related mRNAs. Chungoo Park 2017-09-11 Scientific reports

Transcripts

Name Transcript ID bp Protein Translation ID
SFPQ-207 ENST00000471991 440 No protein -
SFPQ-205 ENST00000468598 2835 No protein -
SFPQ-202 ENST00000460428 464 88aa ENSP00000425071
SFPQ-206 ENST00000470472 874 223aa ENSP00000424440
SFPQ-204 ENST00000466745 662 No protein -
SFPQ-203 ENST00000466213 1431 No protein -
SFPQ-210 ENST00000490668 434 No protein -
SFPQ-208 ENST00000485365 693 No protein -
SFPQ-209 ENST00000485454 339 No protein -
SFPQ-201 ENST00000357214 3740 707aa ENSP00000349748
SFPQ-211 ENST00000696553 4041 728aa ENSP00000512713

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
2826Glucose6.97285092837761E-1117903298
2914Glucose8.45202561052932E-1517903298
2915Glucose1.41968665486179E-1017903298
3043Glucose2.17672047814638E-917903298
4930Triglycerides6.07487614719653E-617903299
7275gamma-Glutamylcyclotransferase2.4649708664903E-517903293
65580Endometrial Neoplasms6E-621499250
105029Schizophrenia7E-626198764

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116560homo_sapiensENSP0000034396669.024956.7878homo_sapiensENSP0000034974851.060842.0085
ENSG00000116560homo_sapiensENSP0000027607973.460759.448homo_sapiensENSP0000034974848.939239.604
ENSG00000116560homo_sapiensENSP0000029442817.655610.9986homo_sapiensENSP0000034974817.25610.7496
ENSG00000116560homo_sapiensENSP0000045454516.40459.10112homo_sapiensENSP0000034974820.650611.4569
ENSG00000116560homo_sapiensENSP000003649126.550223.60262homo_sapiensENSP0000034974833.946318.6704
ENSG00000116560homo_sapiensENSP0000035879914.84147.77891homo_sapiensENSP0000034974820.509210.7496
ENSG00000116560homo_sapiensENSP0000048227719.756412.0433homo_sapiensENSP0000034974820.650612.5884

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464nomascus_leucogenysENSNLEP00000035489100100
ENSG00000116560homo_sapiensENSP0000034974895.615395.6153pan_paniscusENSPPAP0000001386495.345695.3456
ENSG00000116560homo_sapiensENSP00000349748100100pongo_abeliiENSPPYP00000001801100100
ENSG00000116560homo_sapiensENSP0000034974895.756795.7567pan_troglodytesENSPTRP00000069966100100
ENSG00000116560homo_sapiensENSP0000034974883.451283.4512gorilla_gorillaENSGGOP00000021486100100
ENSG00000116560homo_sapiensENSP0000034974885.714383.1683ornithorhynchus_anatinusENSOANP0000003852887.194284.6043
ENSG00000116560homo_sapiensENSP0000034974886.138683.1683sarcophilus_harrisiiENSSHAP0000004066687.249384.2407
ENSG00000116560homo_sapiensENSP0000034974882.178278.2178sarcophilus_harrisiiENSSHAP0000004305784.447780.3779
ENSG00000116560homo_sapiensENSP0000034974872.277270.297notamacropus_eugeniiENSMEUP0000001285373.419571.408
ENSG00000116560homo_sapiensENSP0000034974851.202351.2023choloepus_hoffmanniENSCHOP0000000807495.263295.2632
ENSG00000116560homo_sapiensENSP0000034974897.595597.3126dasypus_novemcinctusENSDNOP0000003084297.595597.3126
ENSG00000116560homo_sapiensENSP0000034974865.48865.3465echinops_telfairiENSETEP0000000088865.673865.5319
ENSG00000116560homo_sapiensENSP0000034974899.292899.1513callithrix_jacchusENSCJAP0000000255199.152599.0113
ENSG00000116560homo_sapiensENSP0000034974890.947790.5233cercocebus_atysENSCATP0000002541095.970195.5224
ENSG00000116560homo_sapiensENSP0000034974899.717199.7171macaca_mulattaENSMMUP0000002517799.717199.7171
ENSG00000116560homo_sapiensENSP0000034974899.858699.8586macaca_nemestrinaENSMNEP0000003092899.858699.8586
ENSG00000116560homo_sapiensENSP0000034974893.776593.6351papio_anubisENSPANP0000005489097.643697.4963
ENSG00000116560homo_sapiensENSP0000034974899.858699.8586papio_anubisENSPANP0000005926599.858699.8586
ENSG00000116560homo_sapiensENSP0000034974843.422942.9986mandrillus_leucophaeusENSMLEP0000002228495.937595
ENSG00000116560homo_sapiensENSP0000034974848.090548.0905mandrillus_leucophaeusENSMLEP00000002598100100
ENSG00000116560homo_sapiensENSP0000034974894.200993.918tursiops_truncatusENSTTRP0000001320795.007194.7218
ENSG00000116560homo_sapiensENSP0000034974844.695944.1301vulpes_vulpesENSVVUP0000000106896.341595.1219
ENSG00000116560homo_sapiensENSP0000034974845.403143.14vulpes_vulpesENSVVUP0000000590280.2576.25
ENSG00000116560homo_sapiensENSP0000034974895.190994.0594mus_spretusMGP_SPRETEiJ_P006697196.280495.1359
ENSG00000116560homo_sapiensENSP0000034974897.736997.5955equus_asinusENSEASP0000501734994.787494.6502
ENSG00000116560homo_sapiensENSP0000034974897.312697.0297capra_hircusENSCHIP0000002698696.765196.4838
ENSG00000116560homo_sapiensENSP0000034974895.615394.9081loxodonta_africanaENSLAFP0000001337896.022795.3125
ENSG00000116560homo_sapiensENSP0000034974898.019897.8784panthera_leoENSPLOP0000000652298.858898.7161
ENSG00000116560homo_sapiensENSP0000034974875.954775.6719ailuropoda_melanoleucaENSAMEP0000000088496.064495.7066
ENSG00000116560homo_sapiensENSP0000034974897.45497.1711bos_indicus_hybridENSBIXP0000504296397.45497.1711
ENSG00000116560homo_sapiensENSP0000034974869.872769.5898oryctolagus_cuniculusENSOCUP0000000161690.642290.2752
ENSG00000116560homo_sapiensENSP0000034974897.736997.5955equus_caballusENSECAP0000002901397.598997.4576
ENSG00000116560homo_sapiensENSP0000034974886.845884.5827canis_lupus_familiarisENSCAFP0084502484592.469990.0602
ENSG00000116560homo_sapiensENSP0000034974897.171197.0297canis_lupus_familiarisENSCAFP0084502120598.706998.5632
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464panthera_pardusENSPPRP0000002524199.715999.7159
ENSG00000116560homo_sapiensENSP0000034974849.646449.505marmota_marmota_marmotaENSMMMP0000000899010099.7151
ENSG00000116560homo_sapiensENSP0000034974838.048134.0877marmota_marmota_marmotaENSMMMP0000000985273.097865.4891
ENSG00000116560homo_sapiensENSP0000034974896.888396.7468balaenoptera_musculusENSBMSP0001000103297.025596.8839
ENSG00000116560homo_sapiensENSP0000034974846.534746.2518cavia_porcellusENSCPOP0000001353695.918495.3353
ENSG00000116560homo_sapiensENSP0000034974898.019897.8784felis_catusENSFCAP0000004616598.858898.7161
ENSG00000116560homo_sapiensENSP0000034974856.8656.86ursus_americanusENSUAMP0000003525999.014899.0148
ENSG00000116560homo_sapiensENSP0000034974886.280183.1683monodelphis_domesticaENSMODP0000004946487.142984
ENSG00000116560homo_sapiensENSP0000034974847.807647.6662bison_bison_bisonENSBBBP0000002594396.848196.5616
ENSG00000116560homo_sapiensENSP0000034974897.312697.0297monodon_monocerosENSMMNP0001501307097.588797.305
ENSG00000116560homo_sapiensENSP0000034974897.736997.3126sus_scrofaENSSSCP0000003865398.433198.0057
ENSG00000116560homo_sapiensENSP0000034974898.444198.3027microcebus_murinusENSMICP0000003195998.723498.5816
ENSG00000116560homo_sapiensENSP0000034974867.751167.6096octodon_degusENSODEP0000000735296.184795.9839
ENSG00000116560homo_sapiensENSP0000034974895.049594.3423jaculus_jaculusENSJJAP0000001264595.184194.4759
ENSG00000116560homo_sapiensENSP0000034974897.45497.1711ovis_aries_rambouilletENSOARP0002001253596.905896.6245
ENSG00000116560homo_sapiensENSP0000034974848.23248.232ursus_maritimusENSUMAP00000010718100100
ENSG00000116560homo_sapiensENSP0000034974880.480979.3494ochotona_princepsENSOPRP0000001249980.709279.5745
ENSG00000116560homo_sapiensENSP0000034974897.45497.1711delphinapterus_leucasENSDLEP0000002866397.730597.4468
ENSG00000116560homo_sapiensENSP0000034974891.089190.8062physeter_catodonENSPCTP0000502590793.063692.7746
ENSG00000116560homo_sapiensENSP0000034974895.190994.0594mus_caroliMGP_CAROLIEiJ_P006446296.142995
ENSG00000116560homo_sapiensENSP0000034974895.190994.0594mus_musculusENSMUSP0000015952993.472292.3611
ENSG00000116560homo_sapiensENSP0000034974897.171196.6054dipodomys_ordiiENSDORP0000000761098.002997.4322
ENSG00000116560homo_sapiensENSP0000034974843.1443.14mustela_putorius_furoENSMPUP0000001482098.070798.0707
ENSG00000116560homo_sapiensENSP0000034974879.066577.5106aotus_nancymaaeENSANAP0000001927587.893186.1635
ENSG00000116560homo_sapiensENSP0000034974839.462537.6238aotus_nancymaaeENSANAP0000004092389.423185.2564
ENSG00000116560homo_sapiensENSP0000034974837.906635.785saimiri_boliviensis_boliviensisENSSBOP0000003553686.731481.877
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464saimiri_boliviensis_boliviensisENSSBOP00000016564100100
ENSG00000116560homo_sapiensENSP0000034974857.708657.5672vicugna_pacosENSVPAP0000000647061.631461.4804
ENSG00000116560homo_sapiensENSP0000034974899.858699.8586chlorocebus_sabaeusENSCSAP0000001693199.717599.7175
ENSG00000116560homo_sapiensENSP0000034974880.905280.0566tupaia_belangeriENSTBEP0000000538590.93889.9841
ENSG00000116560homo_sapiensENSP0000034974895.332494.2009mesocricetus_auratusENSMAUP0000000478495.874894.7368
ENSG00000116560homo_sapiensENSP0000034974897.312697.0297phocoena_sinusENSPSNP0000001982597.588797.305
ENSG00000116560homo_sapiensENSP0000034974876.237673.8331camelus_dromedariusENSCDRP0000503107474.242471.9008
ENSG00000116560homo_sapiensENSP0000034974843.705842.4328carlito_syrichtaENSTSYP0000001558092.51589.8204
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464carlito_syrichtaENSTSYP00000022651100100
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464panthera_tigris_altaicaENSPTIP00000005489100100
ENSG00000116560homo_sapiensENSP0000034974889.957687.4116rattus_norvegicusENSRNOP0000008768990.469487.909
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464prolemur_simusENSPSMP00000030410100100
ENSG00000116560homo_sapiensENSP0000034974865.205164.7808microtus_ochrogasterENSMOCP0000002185898.504397.8633
ENSG00000116560homo_sapiensENSP0000034974852.050952.0509sorex_araneusENSSARP00000005807100100
ENSG00000116560homo_sapiensENSP0000034974868.033967.7511peromyscus_maniculatus_bairdiiENSPEMP0000000801468.812668.5265
ENSG00000116560homo_sapiensENSP0000034974867.609667.6096bos_mutusENSBMUP0000002867268.285768.2857
ENSG00000116560homo_sapiensENSP0000034974895.190994.0594mus_spicilegusENSMSIP0000002000896.142995
ENSG00000116560homo_sapiensENSP0000034974895.615394.6252cricetulus_griseus_chok1gshdENSCGRP0000100962496.159395.1636
ENSG00000116560homo_sapiensENSP0000034974895.332494.9081pteropus_vampyrusENSPVAP0000000176196.561696.1318
ENSG00000116560homo_sapiensENSP0000034974862.376261.8105myotis_lucifugusENSMLUP0000002216398.657797.7629
ENSG00000116560homo_sapiensENSP0000034974885.855782.6025vombatus_ursinusENSVURP0001000505587.338184.0288
ENSG00000116560homo_sapiensENSP0000034974896.746896.4639rhinolophus_ferrumequinumENSRFEP0001000172097.297397.0128
ENSG00000116560homo_sapiensENSP0000034974897.595597.454neovison_visonENSNVIP0000001488498.571498.4286
ENSG00000116560homo_sapiensENSP0000034974897.45497.1711bos_taurusENSBTAP0000002171997.45497.1711
ENSG00000116560homo_sapiensENSP0000034974852.192451.0608heterocephalus_glaber_femaleENSHGLP0000004838096.850494.7507
ENSG00000116560homo_sapiensENSP0000034974875.530474.6818rhinopithecus_bietiENSRBIP0000002267583.437582.5
ENSG00000116560homo_sapiensENSP0000034974845.261745.1202canis_lupus_dingoENSCAFP0002001333498.461598.1538
ENSG00000116560homo_sapiensENSP0000034974886.845884.5827canis_lupus_dingoENSCAFP0002000597792.469990.0602
ENSG00000116560homo_sapiensENSP0000034974897.736997.1711sciurus_vulgarisENSSVLP0000500142298.573598.0029
ENSG00000116560homo_sapiensENSP0000034974858.698756.7185sciurus_vulgarisENSSVLP0000500387082.669379.8805
ENSG00000116560homo_sapiensENSP0000034974886.138682.8854phascolarctos_cinereusENSPCIP0000000111687.249383.9542
ENSG00000116560homo_sapiensENSP0000034974874.681874.2574procavia_capensisENSPCAP0000000578573.74373.324
ENSG00000116560homo_sapiensENSP0000034974895.332494.6252nannospalax_galiliENSNGAP0000000120295.467494.7592
ENSG00000116560homo_sapiensENSP0000034974897.45497.0297bos_grunniensENSBGRP0000001862697.45497.0297
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464chinchilla_lanigeraENSCLAP00000013857100100
ENSG00000116560homo_sapiensENSP0000034974897.45496.8883cervus_hanglu_yarkandensisENSCHYP0000004096997.45496.8883
ENSG00000116560homo_sapiensENSP0000034974897.45497.0297catagonus_wagneriENSCWAP0000001272198.148197.7208
ENSG00000116560homo_sapiensENSP0000034974849.646449.6464ictidomys_tridecemlineatusENSSTOP00000012551100100
ENSG00000116560homo_sapiensENSP0000034974873.691773.6917otolemur_garnettiiENSOGAP0000001773798.487798.4877
ENSG00000116560homo_sapiensENSP0000034974867.043863.9321cebus_imitatorENSCCAP0000002793981.865378.0656
ENSG00000116560homo_sapiensENSP0000034974899.292899.2928cebus_imitatorENSCCAP0000002315499.292899.2928
ENSG00000116560homo_sapiensENSP0000034974868.316860.6789urocitellus_parryiiENSUPAP0001002115273.966365.6968
ENSG00000116560homo_sapiensENSP0000034974897.45497.0297urocitellus_parryiiENSUPAP0001000082998.008597.5818
ENSG00000116560homo_sapiensENSP0000034974897.171196.6054moschus_moschiferusENSMMSP0000001313997.171196.6054
ENSG00000116560homo_sapiensENSP0000034974882.74482.744rhinopithecus_roxellanaENSRROP00000034895100100
ENSG00000116560homo_sapiensENSP0000034974894.625293.4936mus_pahariMGP_PahariEiJ_P007955495.708294.5637
ENSG00000116560homo_sapiensENSP0000034974898.444198.0198propithecus_coquereliENSPCOP0000002890498.583698.1586
ENSG00000116560homo_sapiensENSP0000034974839.038229.1372caenorhabditis_elegansF25B5.7a.149.110336.6548
ENSG00000116560homo_sapiensENSP0000034974816.40749.47666drosophila_melanogasterFBpp008793314.6288.44893
ENSG00000116560homo_sapiensENSP0000034974837.623826.4498drosophila_melanogasterFBpp030587442.222229.6825
ENSG00000116560homo_sapiensENSP0000034974840.311228.7129drosophila_melanogasterFBpp007401238.409727.3585
ENSG00000116560homo_sapiensENSP0000034974814.42727.35502ciona_intestinalisENSCINP0000000514713.42116.84211
ENSG00000116560homo_sapiensENSP0000034974841.86731.5417ciona_intestinalisENSCINP0000000835355.534741.8386
ENSG00000116560homo_sapiensENSP0000034974846.817537.4823petromyzon_marinusENSPMAP0000000618570.27656.2633
ENSG00000116560homo_sapiensENSP0000034974826.166917.8218eptatretus_burgeriENSEBUP0000002286257.632439.2523
ENSG00000116560homo_sapiensENSP0000034974861.527653.7482callorhinchus_miliiENSCMIP0000001736876.991167.2566
ENSG00000116560homo_sapiensENSP0000034974863.932156.86latimeria_chalumnaeENSLACP0000001671972.668864.6302
ENSG00000116560homo_sapiensENSP0000034974866.336657.8501lepisosteus_oculatusENSLOCP000000012266758.4286
ENSG00000116560homo_sapiensENSP0000034974860.820452.0509clupea_harengusENSCHAP0000003319272.268961.8487
ENSG00000116560homo_sapiensENSP0000034974861.527651.3437danio_rerioENSDARP0000002052268.181856.8966
ENSG00000116560homo_sapiensENSP0000034974860.961851.9095carassius_auratusENSCARP0000005986372.315461.5772
ENSG00000116560homo_sapiensENSP0000034974860.678952.6167carassius_auratusENSCARP0000006108771.619462.1035
ENSG00000116560homo_sapiensENSP0000034974862.94253.041astyanax_mexicanusENSAMXP0000001185467.835457.1646
ENSG00000116560homo_sapiensENSP0000034974860.961852.4752ictalurus_punctatusENSIPUP0000001932173.549563.3106
ENSG00000116560homo_sapiensENSP0000034974863.932154.7383esox_luciusENSELUP0000004569170.846460.6583
ENSG00000116560homo_sapiensENSP0000034974862.376253.6068electrophorus_electricusENSEEEP0000001812769.778559.9684
ENSG00000116560homo_sapiensENSP0000034974860.254651.0608oncorhynchus_kisutchENSOKIP0000511025466.355156.2305
ENSG00000116560homo_sapiensENSP0000034974862.659152.8996oncorhynchus_kisutchENSOKIP0000502508267.019756.5809
ENSG00000116560homo_sapiensENSP0000034974859.971750.3536oncorhynchus_mykissENSOMYP0000008229563.759453.5338
ENSG00000116560homo_sapiensENSP0000034974860.113251.0608oncorhynchus_mykissENSOMYP0000008484366.406256.4062
ENSG00000116560homo_sapiensENSP0000034974863.224953.4653salmo_salarENSSSAP0000013108266.320556.0831
ENSG00000116560homo_sapiensENSP0000034974858.274448.9392salmo_salarENSSSAP0000014319863.482353.3128
ENSG00000116560homo_sapiensENSP0000034974862.659153.1825salmo_truttaENSSTUP0000007517663.832954.1787
ENSG00000116560homo_sapiensENSP0000034974859.830350.7779salmo_truttaENSSTUP0000010224266.930456.8038
ENSG00000116560homo_sapiensENSP0000034974839.745434.6535gadus_morhuaENSGMOP0000001278590.064178.5256
ENSG00000116560homo_sapiensENSP0000034974864.922255.8699gadus_morhuaENSGMOP0000006343566.329557.0809
ENSG00000116560homo_sapiensENSP0000034974863.507852.4752fundulus_heteroclitusENSFHEP0000003009660.349549.8656
ENSG00000116560homo_sapiensENSP0000034974863.790752.7581poecilia_reticulataENSPREP0000001186863.610752.6093
ENSG00000116560homo_sapiensENSP0000034974860.678950.3536xiphophorus_maculatusENSXMAP0000001642563.555652.7407
ENSG00000116560homo_sapiensENSP0000034974865.629456.2942oryzias_latipesENSORLP0000000935164.534155.3547
ENSG00000116560homo_sapiensENSP0000034974864.356456.5771cyclopterus_lumpusENSCLMP0000502222970.542662.0155
ENSG00000116560homo_sapiensENSP0000034974866.76157.5672oreochromis_niloticusENSONIP0000007231569.822560.2071
ENSG00000116560homo_sapiensENSP0000034974866.478156.7185haplochromis_burtoniENSHBUP0000001493269.836659.584
ENSG00000116560homo_sapiensENSP0000034974866.478156.86astatotilapia_callipteraENSACLP0000003296569.836659.7325
ENSG00000116560homo_sapiensENSP0000034974865.770958.133sparus_aurataENSSAUP0001006693568.78760.7988
ENSG00000116560homo_sapiensENSP0000034974864.922257.1429lates_calcariferENSLCAP0001002667773.089264.3312
ENSG00000116560homo_sapiensENSP0000034974868.882662.6591xenopus_tropicalisENSXETP0000010936873.123166.5165
ENSG00000116560homo_sapiensENSP0000034974875.671973.1259chrysemys_picta_belliiENSCPBP0000002630882.817380.031
ENSG00000116560homo_sapiensENSP0000034974865.629463.9321crocodylus_porosusENSCPRP0000500013382.857180.7143
ENSG00000116560homo_sapiensENSP0000034974876.379173.9745gallus_gallusENSGALP0001001965983.462180.8346
ENSG00000116560homo_sapiensENSP0000034974862.800660.1132meleagris_gallopavoENSMGAP0000000403272.786969.6721
ENSG00000116560homo_sapiensENSP0000034974849.080646.5347serinus_canariaENSSCAP0000002161980.138675.9815
ENSG00000116560homo_sapiensENSP0000034974876.237673.8331parus_majorENSPMJP0000000812184.350581.6901
ENSG00000116560homo_sapiensENSP0000034974860.254657.0014anolis_carolinensisENSACAP0000003414889.684284.8421
ENSG00000116560homo_sapiensENSP0000034974866.053756.5771neolamprologus_brichardiENSNBRP0000002286470.225660.1504
ENSG00000116560homo_sapiensENSP0000034974860.39658.8402geospiza_fortisENSGFOP0000002004486.262684.0404
ENSG00000116560homo_sapiensENSP0000034974876.237673.6917taeniopygia_guttataENSTGUP0000000178684.350581.5336
ENSG00000116560homo_sapiensENSP0000034974848.090543.2815erpetoichthys_calabaricusENSECRP0000001812481.730873.5577
ENSG00000116560homo_sapiensENSP0000034974865.912356.1528kryptolebias_marmoratusENSKMAP0000000025659.974351.094
ENSG00000116560homo_sapiensENSP0000034974878.217875.5304salvator_merianaeENSSMRP0000001500176.592873.9612
ENSG00000116560homo_sapiensENSP0000034974856.294249.2221oryzias_javanicusENSOJAP0000001294663.578355.5911
ENSG00000116560homo_sapiensENSP0000034974863.790754.5969amphilophus_citrinellusENSACIP0000000120874.422463.6964
ENSG00000116560homo_sapiensENSP0000034974865.346556.1528dicentrarchus_labraxENSDLAP0000507524472.413862.2257
ENSG00000116560homo_sapiensENSP0000034974866.619556.7185amphiprion_perculaENSAPEP0000002327367.478557.4499
ENSG00000116560homo_sapiensENSP0000034974862.234853.041oryzias_sinensisENSOSIP0000002717163.127753.802
ENSG00000116560homo_sapiensENSP0000034974859.123157.7086pelodiscus_sinensisENSPSIP0000001285796.983894.6636
ENSG00000116560homo_sapiensENSP0000034974875.813372.9844chelonoidis_abingdoniiENSCABP0000001199782.334979.2627
ENSG00000116560homo_sapiensENSP0000034974865.912357.8501seriola_dumeriliENSSDUP0000001151172.698963.8066
ENSG00000116560homo_sapiensENSP0000034974865.205157.1429cottoperca_gobioENSCGOP0000003816366.330958.1295
ENSG00000116560homo_sapiensENSP0000034974854.172652.8996struthio_camelus_australisENSSCUP0000001855595.9993.7343
ENSG00000116560homo_sapiensENSP0000034974865.629456.86gasterosteus_aculeatusENSGACP0000000265472.274162.6168
ENSG00000116560homo_sapiensENSP0000034974861.527653.4653cynoglossus_semilaevisENSCSEP0000001219268.720459.7156
ENSG00000116560homo_sapiensENSP0000034974864.639353.7482poecilia_formosaENSPFOP0000000307561.673451.2821
ENSG00000116560homo_sapiensENSP0000034974863.507856.1528myripristis_murdjanENSMMDP0000503036370.932162.7172
ENSG00000116560homo_sapiensENSP0000034974867.185357.8501sander_luciopercaENSSLUP0000005090769.648159.9707
ENSG00000116560homo_sapiensENSP0000034974876.944874.8232strigops_habroptilaENSSHBP0000501237284.210581.8885
ENSG00000116560homo_sapiensENSP0000034974866.619556.7185amphiprion_ocellarisENSAOCP0000000007367.478557.4499
ENSG00000116560homo_sapiensENSP0000034974876.096273.4088terrapene_carolina_triunguisENSTMTP0000000834183.15380.2164
ENSG00000116560homo_sapiensENSP0000034974859.830350.495hucho_huchoENSHHUP0000001944768.557557.8606
ENSG00000116560homo_sapiensENSP0000034974861.103350.9194hucho_huchoENSHHUP0000005041053.59844.665
ENSG00000116560homo_sapiensENSP0000034974868.599759.2645betta_splendensENSBSLP0000003804671.010261.347
ENSG00000116560homo_sapiensENSP0000034974862.94253.7482pygocentrus_nattereriENSPNAP0000000609272.475661.8893
ENSG00000116560homo_sapiensENSP0000034974865.912357.5672anabas_testudineusENSATEP0000000427573.734264.3987
ENSG00000116560homo_sapiensENSP0000034974810.18395.51627ciona_savignyiENSCSAVP0000001882020.224710.9551
ENSG00000116560homo_sapiensENSP0000034974814.99297.63791ciona_savignyiENSCSAVP0000000888915.54257.91789
ENSG00000116560homo_sapiensENSP0000034974865.912357.8501seriola_lalandi_dorsalisENSSLDP0000002427872.472863.6081
ENSG00000116560homo_sapiensENSP0000034974862.94254.4554labrus_bergyltaENSLBEP0000000411463.120654.6099
ENSG00000116560homo_sapiensENSP0000034974866.336656.7185pundamilia_nyerereiENSPNYP0000000986868.869358.884
ENSG00000116560homo_sapiensENSP0000034974865.205157.2843mastacembelus_armatusENSMAMP0000001163073.174664.2857
ENSG00000116560homo_sapiensENSP0000034974867.043858.133stegastes_partitusENSSPAP0000002190971.171261.7117
ENSG00000116560homo_sapiensENSP0000034974860.254650.7779oncorhynchus_tshawytschaENSOTSP0000501773866.149155.7453
ENSG00000116560homo_sapiensENSP0000034974862.94253.1825oncorhynchus_tshawytschaENSOTSP0000506117866.917356.5414
ENSG00000116560homo_sapiensENSP0000034974865.912356.5771acanthochromis_polyacanthusENSAPOP0000002067368.529458.8235
ENSG00000116560homo_sapiensENSP0000034974863.507852.6167nothobranchius_furzeriENSNFUP0001504525663.418152.5424
ENSG00000116560homo_sapiensENSP0000034974862.94253.3239cyprinodon_variegatusENSCVAP0000001656759.892350.7402
ENSG00000116560homo_sapiensENSP0000034974861.103352.0509denticeps_clupeoidesENSDCDP0000003554969.453459.164
ENSG00000116560homo_sapiensENSP0000034974865.912357.2843larimichthys_croceaENSLCRP0000500206071.802862.4037
ENSG00000116560homo_sapiensENSP0000034974865.48856.7185takifugu_rubripesENSTRUP0000000889770.045460.6657
ENSG00000116560homo_sapiensENSP0000034974870.29768.1754ficedula_albicollisENSFALP0000000075483.811181.2816
ENSG00000116560homo_sapiensENSP0000034974863.083554.4554hippocampus_comesENSHCOP0000000676660.680352.381
ENSG00000116560homo_sapiensENSP0000034974860.961852.6167cyprinus_carpio_carpioENSCCRP0000010993672.315462.4161
ENSG00000116560homo_sapiensENSP0000034974860.113251.768cyprinus_carpio_carpioENSCCRP0000015101771.669561.7201
ENSG00000116560homo_sapiensENSP0000034974875.954773.1259coturnix_japonicaENSCJPP0000502137983.385180.2795
ENSG00000116560homo_sapiensENSP0000034974861.386153.1825sinocyclocheilus_grahamiENSSGRP0000008956073.187263.4064
ENSG00000116560homo_sapiensENSP0000034974860.537552.0509sinocyclocheilus_grahamiENSSGRP0000001238472.542462.3729
ENSG00000116560homo_sapiensENSP0000034974865.912356.2942maylandia_zebraENSMZEP0000503489070.075259.8496
ENSG00000116560homo_sapiensENSP0000034974861.66953.4653tetraodon_nigroviridisENSTNIP0000001427474.149764.2857
ENSG00000116560homo_sapiensENSP0000034974863.224956.0113paramormyrops_kingsleyaeENSPKIP0000000696176.804168.0412
ENSG00000116560homo_sapiensENSP0000034974862.093455.1627scleropages_formosusENSSFOP0001505944375.171266.7808
ENSG00000116560homo_sapiensENSP0000034974822.630820.3678leptobrachium_leishanenseENSLLEP0000001160687.431778.6885
ENSG00000116560homo_sapiensENSP0000034974822.630820.3678leptobrachium_leishanenseENSLLEP0000000409490.395581.3559
ENSG00000116560homo_sapiensENSP0000034974862.800655.3041scophthalmus_maximusENSSMAP0000006212770.476262.0635
ENSG00000116560homo_sapiensENSP0000034974865.346556.0113oryzias_melastigmaENSOMEP0000001632663.201154.1724

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II3IDA,IGI,IMPHomo_sapiens(9606)Process
GO:0000380involved_in alternative mRNA splicing, via spliceosome2IBA,IMPHomo_sapiens(9606)Process
GO:0000724acts_upstream_of_or_within double-strand break repair via homologous recombination1IMPHomo_sapiens(9606)Process
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1ISSHomo_sapiens(9606)Function
GO:0002218involved_in activation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1IDAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1ISSHomo_sapiens(9606)Function
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006338involved_in chromatin remodeling1ISSHomo_sapiens(9606)Process
GO:0006355involved_in regulation of DNA-templated transcription1IBAHomo_sapiens(9606)Process
GO:0006397involved_in mRNA processing1TASHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1TASHomo_sapiens(9606)Process
GO:0016363located_in nuclear matrix1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IEAHomo_sapiens(9606)Component
GO:0042382located_in paraspeckles1IDAHomo_sapiens(9606)Component
GO:0042752involved_in regulation of circadian rhythm1ISSHomo_sapiens(9606)Process
GO:0042754involved_in negative regulation of circadian rhythm1ISSHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IPIHomo_sapiens(9606)Function
GO:0042826enables histone deacetylase binding1IPIHomo_sapiens(9606)Function
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1ISSHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0048511involved_in rhythmic process1IEAHomo_sapiens(9606)Process
GO:0090575part_of RNA polymerase II transcription regulator complex1ISSHomo_sapiens(9606)Component
GO:1902177involved_in positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway1IDAHomo_sapiens(9606)Process

Expression