Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000116062 Gene ID 2956 Accession 7329
Symbol MSH6 Alias GTBP;HSAP;p160;GTMBP;MSH-6;HNPCC5;LYNCH5;MMRCS3 Full Name mutS homolog 6
Status Confidence Length 114245 bases Strand Plus strand
Position 2 : 47695819 - 47810063 RNA binding domain MutS_II
Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000514752 MutS_II PF05188 1.3e-11 1
ENSP00000498629 MutS_II PF05188 2.1e-11 1
ENSP00000501310 MutS_II PF05188 2.1e-11 1
ENSP00000446475 MutS_II PF05188 2.1e-11 1
ENSP00000234420 MutS_II PF05188 2.4e-11 1
ENSP00000514750 MutS_II PF05188 2.5e-11 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MSH6-210 ENST00000607272 2219 No protein -
MSH6-205 ENST00000454137 725 No protein -
MSH6-211 ENST00000652107 7669 1261aa ENSP00000498629
MSH6-204 ENST00000445503 4158 160aa ENSP00000405294
MSH6-207 ENST00000456246 846 104aa ENSP00000410570
MSH6-213 ENST00000673922 573 No protein -
MSH6-201 ENST00000234420 4265 1360aa ENSP00000234420
MSH6-214 ENST00000699999 4822 No protein -
MSH6-219 ENST00000700004 3850 1232aa ENSP00000514752
MSH6-215 ENST00000700000 2646 838aa ENSP00000514749
MSH6-212 ENST00000673637 3959 1261aa ENSP00000501310
MSH6-216 ENST00000700001 3059 No protein -
MSH6-217 ENST00000700002 4233 1362aa ENSP00000514750
MSH6-208 ENST00000493177 813 No protein -
MSH6-209 ENST00000540021 3829 1230aa ENSP00000446475
MSH6-218 ENST00000700003 1593 229aa ENSP00000514751
MSH6-206 ENST00000455383 4110 1261aa ENSP00000397484
MSH6-203 ENST00000420813 4106 1261aa ENSP00000390382
MSH6-202 ENST00000411819 3974 1261aa ENSP00000406248
MSH6-220 ENST00000700005 3067 No protein -
MSH6-221 ENST00000700006 5230 No protein -
MSH6-222 ENST00000700007 2750 No protein -
MSH6-223 ENST00000700008 2401 No protein -
MSH6-224 ENST00000700009 2812 No protein -
MSH6-225 ENST00000700010 1547 No protein -
MSH6-226 ENST00000700011 3433 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
42039Platelet Function Tests1.7351700E-005-
42050Platelet Function Tests2.2146622E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116062homo_sapiensENSP0000023314641.755924.5182homo_sapiensENSP0000023442028.676516.8382
ENSG00000116062homo_sapiensENSP0000026318737.713719.765homo_sapiensENSP0000023442025.955913.6029
ENSG00000116062homo_sapiensENSP0000036490337.410119.9041homo_sapiensENSP0000023442022.941212.2059
ENSG00000116062homo_sapiensENSP0000026508145.206725.6816homo_sapiensENSP0000023442037.794121.4706

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000116062homo_sapiensENSP0000023442093.088292.5735nomascus_leucogenysENSNLEP0000001040399.450198.9002
ENSG00000116062homo_sapiensENSP0000023442094.044193.4559pan_paniscusENSPPAP0000003765298.082897.4693
ENSG00000116062homo_sapiensENSP0000023442099.558899.0441pongo_abeliiENSPPYP0000001387399.412698.8987
ENSG00000116062homo_sapiensENSP0000023442099.632499.4118pan_troglodytesENSPTRP0000002043499.632499.4118
ENSG00000116062homo_sapiensENSP0000023442099.779499.7059gorilla_gorillaENSGGOP0000001892499.779499.7059
ENSG00000116062homo_sapiensENSP0000023442079.191266.25ornithorhynchus_anatinusENSOANP0000005257778.728165.8626
ENSG00000116062homo_sapiensENSP0000023442087.720678.75sarcophilus_harrisiiENSSHAP0000000927785.275276.5547
ENSG00000116062homo_sapiensENSP0000023442049.852943.2353notamacropus_eugeniiENSMEUP0000000932654.633447.3811
ENSG00000116062homo_sapiensENSP0000023442052.550.7353choloepus_hoffmanniENSCHOP0000001188552.732650.9601
ENSG00000116062homo_sapiensENSP0000023442095.294192.0588dasypus_novemcinctusENSDNOP0000002671495.645892.3985
ENSG00000116062homo_sapiensENSP0000023442051.838249.2647erinaceus_europaeusENSEEUP0000000559461.896458.8235
ENSG00000116062homo_sapiensENSP0000023442058.7555.4412echinops_telfairiENSETEP0000000509659.05455.728
ENSG00000116062homo_sapiensENSP0000023442097.058895.9559callithrix_jacchusENSCJAP0000004726596.703395.6044
ENSG00000116062homo_sapiensENSP0000023442021.691221.1029cercocebus_atysENSCATP0000002439694.855392.283
ENSG00000116062homo_sapiensENSP0000023442098.455998.0882macaca_fascicularisENSMFAP0000000792898.528398.1604
ENSG00000116062homo_sapiensENSP0000023442098.676598.3088macaca_mulattaENSMMUP0000003008598.676598.3088
ENSG00000116062homo_sapiensENSP0000023442088.161887.1324macaca_nemestrinaENSMNEP0000003293297.479796.3415
ENSG00000116062homo_sapiensENSP0000023442098.823598.3824papio_anubisENSPANP0000000762698.823598.3824
ENSG00000116062homo_sapiensENSP0000023442096.838296.25mandrillus_leucophaeusENSMLEP0000002009796.625196.0382
ENSG00000116062homo_sapiensENSP0000023442094.191290.8088tursiops_truncatusENSTTRP0000000764094.678591.2786
ENSG00000116062homo_sapiensENSP0000023442096.397192.7206vulpes_vulpesENSVVUP0000000747296.326292.6525
ENSG00000116062homo_sapiensENSP0000023442085.514779.4853mus_spretusMGP_SPRETEiJ_P004775090.22583.8635
ENSG00000116062homo_sapiensENSP0000023442096.2593.4559equus_asinusENSEASP0000504712593.433390.7209
ENSG00000116062homo_sapiensENSP0000023442095.514791.25capra_hircusENSCHIP0000001233095.444591.183
ENSG00000116062homo_sapiensENSP0000023442089.926586.9853loxodonta_africanaENSLAFP0000000132895.921692.7843
ENSG00000116062homo_sapiensENSP0000023442095.735392.1324panthera_leoENSPLOP0000000542095.735392.1324
ENSG00000116062homo_sapiensENSP0000023442095.808892.3529ailuropoda_melanoleucaENSAMEP0000000666295.668192.2173
ENSG00000116062homo_sapiensENSP0000023442095.735392.0588bos_indicus_hybridENSBIXP0000503890695.66591.9912
ENSG00000116062homo_sapiensENSP0000023442094.852991.0294oryctolagus_cuniculusENSOCUP0000001256994.783290.9625
ENSG00000116062homo_sapiensENSP0000023442096.323593.3824equus_caballusENSECAP0000004612693.504690.6495
ENSG00000116062homo_sapiensENSP0000023442096.544192.9412canis_lupus_familiarisENSCAFP0084500765396.473292.8729
ENSG00000116062homo_sapiensENSP0000023442095.661892.0588panthera_pardusENSPPRP0000002871095.661892.0588
ENSG00000116062homo_sapiensENSP0000023442090.514787.5735marmota_marmota_marmotaENSMMMP0000001052196.624893.4851
ENSG00000116062homo_sapiensENSP0000023442095.514792.5balaenoptera_musculusENSBMSP0001003030595.514792.5
ENSG00000116062homo_sapiensENSP0000023442092.058887.7941cavia_porcellusENSCPOP0000000083693.712689.3713
ENSG00000116062homo_sapiensENSP0000023442095.588291.7647felis_catusENSFCAP0000000657895.658691.8322
ENSG00000116062homo_sapiensENSP0000023442089.191286.3235ursus_americanusENSUAMP0000001771596.269893.1746
ENSG00000116062homo_sapiensENSP0000023442087.794178.5294monodelphis_domesticaENSMODP0000000134475.378867.4242
ENSG00000116062homo_sapiensENSP0000023442095.661891.9853bison_bison_bisonENSBBBP0000001674295.661891.9853
ENSG00000116062homo_sapiensENSP0000023442095.367692.2059monodon_monocerosENSMMNP0001501572785.780482.9365
ENSG00000116062homo_sapiensENSP0000023442095.514792.4265sus_scrofaENSSSCP0000002776795.374592.2907
ENSG00000116062homo_sapiensENSP0000023442096.323593.4559microcebus_murinusENSMICP0000003167396.252893.3872
ENSG00000116062homo_sapiensENSP0000023442091.176585.7353octodon_degusENSODEP0000001715592.193386.6915
ENSG00000116062homo_sapiensENSP0000023442089.632483.8971jaculus_jaculusENSJJAP0000000436291.038185.2128
ENSG00000116062homo_sapiensENSP0000023442095.588291.5441ovis_aries_rambouilletENSOARP0002000615095.51891.4769
ENSG00000116062homo_sapiensENSP0000023442089.264786.4706ursus_maritimusENSUMAP0000001797096.349293.3333
ENSG00000116062homo_sapiensENSP0000023442074.117670.2941ochotona_princepsENSOPRP0000000445874.281570.4495
ENSG00000116062homo_sapiensENSP0000023442095.367692.2059delphinapterus_leucasENSDLEP0000000114585.780482.9365
ENSG00000116062homo_sapiensENSP0000023442095.220692.0588physeter_catodonENSPCTP0000501784495.220692.0588
ENSG00000116062homo_sapiensENSP0000023442092.132485.7353mus_caroliMGP_CAROLIEiJ_P004582592.132485.7353
ENSG00000116062homo_sapiensENSP0000023442092.205985.8824mus_musculusENSMUSP0000000550392.341786.0088
ENSG00000116062homo_sapiensENSP0000023442091.838286.9118dipodomys_ordiiENSDORP0000001180993.20988.209
ENSG00000116062homo_sapiensENSP0000023442095.514791.4706mustela_putorius_furoENSMPUP0000001092395.514791.4706
ENSG00000116062homo_sapiensENSP0000023442097.647196.9118aotus_nancymaaeENSANAP0000001193198.589597.8471
ENSG00000116062homo_sapiensENSP0000023442098.235397.7941saimiri_boliviensis_boliviensisENSSBOP0000000227698.3897.9381
ENSG00000116062homo_sapiensENSP0000023442053.602951.6176vicugna_pacosENSVPAP0000000717757.221455.102
ENSG00000116062homo_sapiensENSP0000023442098.823598.3088chlorocebus_sabaeusENSCSAP0000000974598.823598.3088
ENSG00000116062homo_sapiensENSP0000023442068.970666.6176tupaia_belangeriENSTBEP0000001491673.800271.2825
ENSG00000116062homo_sapiensENSP0000023442095.441292.1324phocoena_sinusENSPSNP0000001285595.37192.0647
ENSG00000116062homo_sapiensENSP0000023442095.514792.3529camelus_dromedariusENSCDRP0000503288795.304592.1497
ENSG00000116062homo_sapiensENSP0000023442092.279489.5588carlito_syrichtaENSTSYP0000002541896.538593.6923
ENSG00000116062homo_sapiensENSP0000023442090.441287.3529panthera_tigris_altaicaENSPTIP0000000300790.308487.2247
ENSG00000116062homo_sapiensENSP0000023442092.426585.8088rattus_norvegicusENSRNOP0000007617792.358685.7458
ENSG00000116062homo_sapiensENSP0000023442096.470693.0882prolemur_simusENSPSMP0000001525296.470693.0882
ENSG00000116062homo_sapiensENSP0000023442093.161887.6471microtus_ochrogasterENSMOCP0000001921393.093387.5827
ENSG00000116062homo_sapiensENSP0000023442082.205977.7206sorex_araneusENSSARP0000000182393.244488.1568
ENSG00000116062homo_sapiensENSP0000023442087.352981.8382peromyscus_maniculatus_bairdiiENSPEMP0000001355893.987388.0538
ENSG00000116062homo_sapiensENSP0000023442095.588291.9853bos_mutusENSBMUP0000000673395.588291.9853
ENSG00000116062homo_sapiensENSP0000023442091.764785.3676mus_spicilegusENSMSIP0000002942992.035485.6195
ENSG00000116062homo_sapiensENSP0000023442092.586.5441cricetulus_griseus_chok1gshdENSCGRP0000100501392.704586.7354
ENSG00000116062homo_sapiensENSP0000023442094.852991.1765pteropus_vampyrusENSPVAP0000001027895.202991.5129
ENSG00000116062homo_sapiensENSP0000023442094.705990.8088myotis_lucifugusENSMLUP0000000800694.915391.0096
ENSG00000116062homo_sapiensENSP0000023442087.867678.6765vombatus_ursinusENSVURP0001001994683.217374.5125
ENSG00000116062homo_sapiensENSP0000023442095.367691.9118rhinolophus_ferrumequinumENSRFEP0001000777995.719692.2509
ENSG00000116062homo_sapiensENSP0000023442090.661886.9853neovison_visonENSNVIP0000002973295.433491.5635
ENSG00000116062homo_sapiensENSP0000023442089.705986.8382bos_taurusENSBTAP0000000186796.67293.5816
ENSG00000116062homo_sapiensENSP0000023442094.191290.3676heterocephalus_glaber_femaleENSHGLP0000005391994.260590.4341
ENSG00000116062homo_sapiensENSP0000023442093.823593.0147rhinopithecus_bietiENSRBIP0000000402697.777896.9349
ENSG00000116062homo_sapiensENSP0000023442096.544192.9412canis_lupus_dingoENSCAFP0002003401996.473292.8729
ENSG00000116062homo_sapiensENSP0000023442095.514792.4265sciurus_vulgarisENSSVLP0000502864795.234692.1554
ENSG00000116062homo_sapiensENSP0000023442087.867679.1912phascolarctos_cinereusENSPCIP0000003512385.357176.9286
ENSG00000116062homo_sapiensENSP0000023442093.235388.9706procavia_capensisENSPCAP0000001352893.441489.1673
ENSG00000116062homo_sapiensENSP0000023442021.985320.9559nannospalax_galiliENSNGAP0000000618193.437589.0625
ENSG00000116062homo_sapiensENSP0000023442095.588291.9118bos_grunniensENSBGRP0000001497995.588291.9118
ENSG00000116062homo_sapiensENSP0000023442091.985387.5735chinchilla_lanigeraENSCLAP0000000441194.916590.3642
ENSG00000116062homo_sapiensENSP0000023442095.808892.2059cervus_hanglu_yarkandensisENSCHYP0000001429095.738492.1381
ENSG00000116062homo_sapiensENSP0000023442094.632491.1029catagonus_wagneriENSCWAP0000000512694.632491.1029
ENSG00000116062homo_sapiensENSP0000023442095.882492.4265ictidomys_tridecemlineatusENSSTOP0000001660095.741692.2907
ENSG00000116062homo_sapiensENSP0000023442095.808893.0882otolemur_garnettiiENSOGAP0000002121595.738493.0198
ENSG00000116062homo_sapiensENSP0000023442091.764791.0294cebus_imitatorENSCCAP0000002902396.819296.0434
ENSG00000116062homo_sapiensENSP0000023442095.882492.3529urocitellus_parryiiENSUPAP0001002600695.741692.2173
ENSG00000116062homo_sapiensENSP0000023442095.073591.6176moschus_moschiferusENSMMSP0000001282095.003791.5503
ENSG00000116062homo_sapiensENSP0000023442092.426591.8382rhinopithecus_roxellanaENSRROP0000002188092.426591.8382
ENSG00000116062homo_sapiensENSP0000023442092.132485.3676mus_pahariMGP_PahariEiJ_P004533792.200185.4305
ENSG00000116062homo_sapiensENSP0000023442086.029482.7941propithecus_coquereliENSPCOP0000000751095.199391.6192
ENSG00000116062homo_sapiensENSP0000023442047.867630.8824caenorhabditis_elegansY47G6A.11.154.890435.4132
ENSG00000116062homo_sapiensENSP0000023442053.602936.7647drosophila_melanogasterFBpp007539961.260542.0168
ENSG00000116062homo_sapiensENSP000002344206043.9706ciona_intestinalisENSCINP0000000890765.2847.84
ENSG00000116062homo_sapiensENSP0000023442068.676554.2647petromyzon_marinusENSPMAP0000000933667.779453.5559
ENSG00000116062homo_sapiensENSP0000023442065.955949.7794eptatretus_burgeriENSEBUP0000000459864.393448.6001
ENSG00000116062homo_sapiensENSP0000023442067.205954.1176callorhinchus_miliiENSCMIP0000000678477.986462.7986
ENSG00000116062homo_sapiensENSP0000023442078.970666.1029latimeria_chalumnaeENSLACP0000001718778.912666.0544
ENSG00000116062homo_sapiensENSP0000023442075.661862.3529lepisosteus_oculatusENSLOCP0000002011475.94162.583
ENSG00000116062homo_sapiensENSP0000023442075.882460.2206clupea_harengusENSCHAP0000004367473.925558.6676
ENSG00000116062homo_sapiensENSP0000023442074.191259.9265danio_rerioENSDARP0000013117273.703459.5325
ENSG00000116062homo_sapiensENSP0000023442074.705960.5147carassius_auratusENSCARP0000002672074.323360.2048
ENSG00000116062homo_sapiensENSP0000023442012.132410.2206astyanax_mexicanusENSAMXP0000004305872.687261.2335
ENSG00000116062homo_sapiensENSP0000023442073.897158.6765astyanax_mexicanusENSAMXP0000000115974.776859.375
ENSG00000116062homo_sapiensENSP000002344207558.8235ictalurus_punctatusENSIPUP0000002766871.428656.0224
ENSG00000116062homo_sapiensENSP0000023442074.411859.6324esox_luciusENSELUP0000000986872.963258.4715
ENSG00000116062homo_sapiensENSP0000023442075.441260.5882electrophorus_electricusENSEEEP0000004634574.835960.1021
ENSG00000116062homo_sapiensENSP0000023442074.779459.9265oncorhynchus_kisutchENSOKIP0000501384073.376658.8023
ENSG00000116062homo_sapiensENSP0000023442075.147160.2206oncorhynchus_mykissENSOMYP0000006434073.684259.0483
ENSG00000116062homo_sapiensENSP0000023442074.191259.7059salmo_salarENSSSAP0000004092170.362656.6248
ENSG00000116062homo_sapiensENSP0000023442074.779460.1471salmo_truttaENSSTUP0000002383673.218158.8913
ENSG00000116062homo_sapiensENSP0000023442074.338259.4118gadus_morhuaENSGMOP0000001711872.162757.6731
ENSG00000116062homo_sapiensENSP0000023442069.705954.9265fundulus_heteroclitusENSFHEP0000000530272.86757.4174
ENSG00000116062homo_sapiensENSP0000023442074.411860.1471poecilia_reticulataENSPREP0000003411173.333359.2754
ENSG00000116062homo_sapiensENSP0000023442074.411860.0735xiphophorus_maculatusENSXMAP0000004123573.546559.375
ENSG00000116062homo_sapiensENSP0000023442074.705960.5147oryzias_latipesENSORLP0000001389373.569959.5945
ENSG00000116062homo_sapiensENSP0000023442073.088258.8235cyclopterus_lumpusENSCLMP0000501255472.820558.6081
ENSG00000116062homo_sapiensENSP0000023442074.338260.6618oreochromis_niloticusENSONIP0000005365673.207859.7393
ENSG00000116062homo_sapiensENSP0000023442065.220654.1912haplochromis_burtoniENSHBUP0000000831774.412861.8289
ENSG00000116062homo_sapiensENSP0000023442073.602959.5588astatotilapia_callipteraENSACLP0000000033069.465756.211
ENSG00000116062homo_sapiensENSP0000023442074.264760.2941sparus_aurataENSSAUP0001006367872.871659.1631
ENSG00000116062homo_sapiensENSP0000023442068.382456.6176lates_calcariferENSLCAP0001004463174.939662.0467
ENSG00000116062homo_sapiensENSP0000023442078.529465.9559xenopus_tropicalisENSXETP0000010984777.335364.9529
ENSG00000116062homo_sapiensENSP0000023442067.794158.75chrysemys_picta_belliiENSCPBP0000002852785.370473.9815
ENSG00000116062homo_sapiensENSP0000023442076.544164.3382sphenodon_punctatusENSSPUP0000002447082.948269.7211
ENSG00000116062homo_sapiensENSP0000023442079.926569.6324crocodylus_porosusENSCPRP0000502095380.938270.5138
ENSG00000116062homo_sapiensENSP0000023442070.294156.25laticauda_laticaudataENSLLTP0000000774379.866363.9098
ENSG00000116062homo_sapiensENSP0000023442075.441260.4412notechis_scutatusENSNSUP0000002253879.596663.7704
ENSG00000116062homo_sapiensENSP0000023442077.058861.3235pseudonaja_textilisENSPTXP0000001157478.560762.5187
ENSG00000116062homo_sapiensENSP000002344208068.3824anas_platyrhynchos_platyrhynchosENSAPLP0000001590474.418663.6115
ENSG00000116062homo_sapiensENSP0000023442079.264767.5gallus_gallusENSGALP0001002538780.387868.4564
ENSG00000116062homo_sapiensENSP0000023442078.602966.7647meleagris_gallopavoENSMGAP0000000500177.972366.229
ENSG00000116062homo_sapiensENSP0000023442076.397166.1765serinus_canariaENSSCAP0000001640382.329671.3154
ENSG00000116062homo_sapiensENSP0000023442078.970667.5parus_majorENSPMJP0000000505176.441365.3381
ENSG00000116062homo_sapiensENSP0000023442075.661860.6618anolis_carolinensisENSACAP0000001384977.71962.3112
ENSG00000116062homo_sapiensENSP0000023442072.058859.4853neolamprologus_brichardiENSNBRP0000001973972.646459.9703
ENSG00000116062homo_sapiensENSP0000023442076.470661.1029naja_najaENSNNAP0000000044678.019562.3406
ENSG00000116062homo_sapiensENSP0000023442075.808861.1029podarcis_muralisENSPMRP0000000228477.577162.5282
ENSG00000116062homo_sapiensENSP0000023442071.102961.1029geospiza_fortisENSGFOP0000000651881.672370.1858
ENSG00000116062homo_sapiensENSP0000023442076.102965.3676taeniopygia_guttataENSTGUP0000000572582.012770.4437
ENSG00000116062homo_sapiensENSP0000023442077.867663.75erpetoichthys_calabaricusENSECRP0000002726278.270564.0798
ENSG00000116062homo_sapiensENSP0000023442074.632460kryptolebias_marmoratusENSKMAP0000002213373.126858.7896
ENSG00000116062homo_sapiensENSP0000023442076.397161.5441salvator_merianaeENSSMRP0000001912677.595262.5093
ENSG00000116062homo_sapiensENSP000002344207560.4412oryzias_javanicusENSOJAP0000001489174.127959.7384
ENSG00000116062homo_sapiensENSP0000023442073.897160.2941amphilophus_citrinellusENSACIP0000002801472.878959.4634
ENSG00000116062homo_sapiensENSP0000023442074.044160.6618dicentrarchus_labraxENSDLAP0000502050671.015558.1805
ENSG00000116062homo_sapiensENSP0000023442074.705960.1471amphiprion_perculaENSAPEP0000002003873.516659.1896
ENSG00000116062homo_sapiensENSP0000023442074.558860.5147oryzias_sinensisENSOSIP0000003352973.425159.5945
ENSG00000116062homo_sapiensENSP0000023442077.132466.9118pelodiscus_sinensisENSPSIP0000000532881.761570.9275
ENSG00000116062homo_sapiensENSP0000023442069.485359.4118gopherus_evgoodeiENSGEVP0000500204883.333371.2522
ENSG00000116062homo_sapiensENSP0000023442077.720667.5735chelonoidis_abingdoniiENSCABP0000001186483.955572.9944
ENSG00000116062homo_sapiensENSP0000023442073.7559.8529seriola_dumeriliENSSDUP0000000881573.91359.9853
ENSG00000116062homo_sapiensENSP0000023442073.529459.0441cottoperca_gobioENSCGOP0000005637771.839157.6868
ENSG00000116062homo_sapiensENSP0000023442077.205966.9853struthio_camelus_australisENSSCUP0000000562481.967271.1163
ENSG00000116062homo_sapiensENSP0000023442079.558868.4559anser_brachyrhynchusENSABRP0000002158082.469570.9604
ENSG00000116062homo_sapiensENSP0000023442073.602959.4118gasterosteus_aculeatusENSGACP0000000716073.012458.9351
ENSG00000116062homo_sapiensENSP0000023442071.691257.9412cynoglossus_semilaevisENSCSEP0000001937872.598758.6746
ENSG00000116062homo_sapiensENSP0000023442074.852960.4412poecilia_formosaENSPFOP0000001550273.821659.6084
ENSG00000116062homo_sapiensENSP0000023442075.367660.1471myripristis_murdjanENSMMDP0000501212673.953859.0188
ENSG00000116062homo_sapiensENSP0000023442073.823559.4118sander_luciopercaENSSLUP0000000118773.018258.7636
ENSG00000116062homo_sapiensENSP0000023442079.558868.3824strigops_habroptilaENSSHBP0000501785979.267468.1319
ENSG00000116062homo_sapiensENSP0000023442074.852960.4412amphiprion_ocellarisENSAOCP0000000184473.661459.479
ENSG00000116062homo_sapiensENSP0000023442077.647167.4265terrapene_carolina_triunguisENSTMTP0000000630183.876172.8356
ENSG00000116062homo_sapiensENSP0000023442074.632460.1471hucho_huchoENSHHUP0000000241273.232359.0188
ENSG00000116062homo_sapiensENSP0000023442074.338260betta_splendensENSBSLP0000004191773.207859.0876
ENSG00000116062homo_sapiensENSP0000023442076.2560.9559pygocentrus_nattereriENSPNAP0000002384475.144960.0725
ENSG00000116062homo_sapiensENSP0000023442070.808858.0882anabas_testudineusENSATEP0000002793475.886562.2537
ENSG00000116062homo_sapiensENSP0000023442061.764744.0441ciona_savignyiENSCSAVP0000000684465.318846.5785
ENSG00000116062homo_sapiensENSP0000023442043.308826.4706saccharomyces_cerevisiaeYDR097C47.423528.9855
ENSG00000116062homo_sapiensENSP0000023442074.411860.1471seriola_lalandi_dorsalisENSSLDP0000002792673.174359.1468
ENSG00000116062homo_sapiensENSP0000023442074.852960.0735labrus_bergyltaENSLBEP0000002141473.661459.1172
ENSG00000116062homo_sapiensENSP0000023442057.544.4118labrus_bergyltaENSLBEP0000001661268.118552.6132
ENSG00000116062homo_sapiensENSP0000023442073.676559.4118pundamilia_nyerereiENSPNYP0000002424272.661358.5932
ENSG00000116062homo_sapiensENSP0000023442074.779460.5147mastacembelus_armatusENSMAMP0000003206073.642359.5945
ENSG00000116062homo_sapiensENSP0000023442074.926560.5147stegastes_partitusENSSPAP0000002730273.840659.6377
ENSG00000116062homo_sapiensENSP000002344207560oncorhynchus_tshawytschaENSOTSP0000504308273.593158.8745
ENSG00000116062homo_sapiensENSP000002344207560.7353acanthochromis_polyacanthusENSAPOP0000001929774.074159.9855
ENSG00000116062homo_sapiensENSP0000023442080.147169.1176aquila_chrysaetos_chrysaetosENSACCP0002002320179.620268.6633
ENSG00000116062homo_sapiensENSP0000023442074.558860.2206nothobranchius_furzeriENSNFUP0001501284872.068258.209
ENSG00000116062homo_sapiensENSP0000023442073.602960.4412cyprinodon_variegatusENSCVAP0000002386375.263261.8045
ENSG00000116062homo_sapiensENSP0000023442074.117659.6324denticeps_clupeoidesENSDCDP0000001599173.954559.5011
ENSG00000116062homo_sapiensENSP0000023442074.485360larimichthys_croceaENSLCRP0000503235873.035358.832
ENSG00000116062homo_sapiensENSP0000023442074.632460.1471takifugu_rubripesENSTRUP0000003437773.925759.5776
ENSG00000116062homo_sapiensENSP0000023442076.2565.5147ficedula_albicollisENSFALP0000001161382.301670.7143
ENSG00000116062homo_sapiensENSP0000023442073.602959.9265hippocampus_comesENSHCOP0000001011172.859.2727
ENSG00000116062homo_sapiensENSP0000023442074.852960.6618cyprinus_carpio_carpioENSCCRP0000012690574.252460.1751
ENSG00000116062homo_sapiensENSP0000023442074.264759.9265cyprinus_carpio_carpioENSCCRP0000010595173.884459.6196
ENSG00000116062homo_sapiensENSP0000023442078.823566.3235coturnix_japonicaENSCJPP0000500149280.119667.414
ENSG00000116062homo_sapiensENSP0000023442074.705960.0735poecilia_latipinnaENSPLAP0000002372573.7359.2888
ENSG00000116062homo_sapiensENSP0000023442017.794115.8824sinocyclocheilus_grahamiENSSGRP0000005962583.448374.4828
ENSG00000116062homo_sapiensENSP0000023442069.779455.4412sinocyclocheilus_grahamiENSSGRP0000004227968.028754.0502
ENSG00000116062homo_sapiensENSP0000023442073.7559.5588maylandia_zebraENSMZEP0000500871672.733958.7382
ENSG00000116062homo_sapiensENSP0000023442073.970660.7353tetraodon_nigroviridisENSTNIP0000001970873.323660.2041
ENSG00000116062homo_sapiensENSP0000023442075.220660.2206paramormyrops_kingsleyaeENSPKIP0000001621474.454159.607
ENSG00000116062homo_sapiensENSP0000023442076.102961.3235scleropages_formosusENSSFOP0001500249875.163460.5664
ENSG00000116062homo_sapiensENSP0000023442075.808864.6324leptobrachium_leishanenseENSLLEP0000001608680.546968.6719
ENSG00000116062homo_sapiensENSP0000023442018.235315.2941scophthalmus_maximusENSSMAP0000001342076.307764
ENSG00000116062homo_sapiensENSP000002344207560.6618oryzias_melastigmaENSOMEP0000000043273.91359.7826

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000287contributes_to magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0000400contributes_to four-way junction DNA binding1IDAHomo_sapiens(9606)Function
GO:0000710involved_in meiotic mismatch repair1ISSHomo_sapiens(9606)Process
GO:0000785part_of chromatin1IEAHomo_sapiens(9606)Component
GO:0003682enables chromatin binding1IEAHomo_sapiens(9606)Function
GO:0003690contributes_to double-stranded DNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524contributes_to ATP binding1IDAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006281involved_in DNA repair1IDAHomo_sapiens(9606)Process
GO:0006298involved_in mismatch repair4IBA,IDA,IGI,IMPHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1IEAHomo_sapiens(9606)Process
GO:0008094enables ATP-dependent activity, acting on DNA1IDAHomo_sapiens(9606)Function
GO:0008340involved_in determination of adult lifespan1ISSHomo_sapiens(9606)Process
GO:0008630involved_in intrinsic apoptotic signaling pathway in response to DNA damage1ISSHomo_sapiens(9606)Process
GO:0009411involved_in response to UV1ISSHomo_sapiens(9606)Process
GO:0016446involved_in somatic hypermutation of immunoglobulin genes1ISSHomo_sapiens(9606)Process
GO:0016447involved_in somatic recombination of immunoglobulin gene segments1ISSHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030983enables mismatched DNA binding3IBA,IDAHomo_sapiens(9606)Function
GO:0032137contributes_to guanine/thymine mispair binding1IDAHomo_sapiens(9606)Function
GO:0032142contributes_to single guanine insertion binding1IDAHomo_sapiens(9606)Function
GO:0032143contributes_to single thymine insertion binding1IDAHomo_sapiens(9606)Function
GO:0032301part_of MutSalpha complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0032357contributes_to oxidized purine DNA binding1IDAHomo_sapiens(9606)Function
GO:0032405contributes_to MutLalpha complex binding1IDAHomo_sapiens(9606)Function
GO:0035064enables methylated histone binding1IDAHomo_sapiens(9606)Function
GO:0042803NOT enables protein homodimerization activity1IPIHomo_sapiens(9606)Function
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0043531contributes_to ADP binding1IDAHomo_sapiens(9606)Function
GO:0043570NOT involved_in maintenance of DNA repeat elements1IMPHomo_sapiens(9606)Process
GO:0045190involved_in isotype switching1ISSHomo_sapiens(9606)Process
GO:0045910involved_in negative regulation of DNA recombination1IDAHomo_sapiens(9606)Process
GO:0051096involved_in positive regulation of helicase activity1IDAHomo_sapiens(9606)Process
GO:0097193involved_in intrinsic apoptotic signaling pathway1ISSHomo_sapiens(9606)Process
GO:0140664enables ATP-dependent DNA damage sensor activity1IEAHomo_sapiens(9606)Function

Expression