Ensembl ID ENSG00000116062 Gene ID 2956 Accession 7329
Gene Symbol MSH6 Alias GTBP;HSAP;p160;GTMBP;MSH-6;HNPCC5;LYNCH5;MMRCS3 Full Name mutS homolog 6
Position 2 : 47695819 - 47810063 Length 114245 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

ENSG00000116062 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116062 MSH6 0.74 2.28e-17 HNSC
ENSG00000116062 MSH6 0.55 7.17e-22 BRCA
ENSG00000116062 MSH6 0.67 4.22e-19 COAD
ENSG00000116062 MSH6 1.42 1.44e-52 LUSC
ENSG00000116062 MSH6 0.71 1.32e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000116062 MSH6 breast cancer 10098729
ENSG00000116062 MSH6 colon cancer 10190549
ENSG00000116062 MSH6 lung cancers 10190568
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 10211513
ENSG00000116062 MSH6 tumors 10348818
ENSG00000116062 MSH6 tumors 10383166
ENSG00000116062 MSH6 ovarian cancer 10388122
ENSG00000116062 MSH6 pancreatic cancer 10404064
ENSG00000116062 MSH6 epithelial ovarian cancer 10408416
ENSG00000116062 MSH6 tumor 10413423
ENSG00000116062 MSH6 tumours 10419591
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 10448273
ENSG00000116062 MSH6 tumor 10469448
ENSG00000116062 MSH6 tumours 10470121
ENSG00000116062 MSH6 colorectal cancer 10471527
ENSG00000116062 MSH6 colorectal cancer 10480359
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 10495924
ENSG00000116062 MSH6 lymphoid tumors 10498615
ENSG00000116062 MSH6 tumors 10503872
ENSG00000116062 MSH6 colorectal cancer 10507723
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 10521294
ENSG00000116062 MSH6 colorectal cancer 10544224
ENSG00000116062 MSH6 cancer 10545954
ENSG00000116062 MSH6 tumors 10597289
ENSG00000116062 MSH6 tumours 10601558
ENSG00000116062 MSH6 colorectal cancer 10607839
ENSG00000116062 MSH6 cancers 10630171
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 10630180
ENSG00000116062 MSH6 cancers 10637515
ENSG00000116062 MSH6 tumors 10665647
ENSG00000116062 MSH6 colorectal cancer 10674020
ENSG00000116062 MSH6 tumors 10675480
ENSG00000116062 MSH6 breast tumor 10688660
ENSG00000116062 MSH6 tumors 10699890
ENSG00000116062 MSH6 colorectal cancer 10699937
ENSG00000116062 MSH6 tumor 10706084
ENSG00000116062 MSH6 endometrial cancer 10717241
ENSG00000116062 MSH6 tumors 10719374
ENSG00000116062 MSH6 endometrial tumor 10751599
ENSG00000116062 MSH6 colon cancer 10753784
ENSG00000116062 MSH6 tumor 10783165
ENSG00000116062 MSH6 colorectal cancer 10786688
ENSG00000116062 MSH6 tumors 10820351
ENSG00000116062 MSH6 cancer 10861263
ENSG00000116062 MSH6 colon cancers 10861498
ENSG00000116062 MSH6 tumors 10918391
ENSG00000116062 MSH6 colon cancer 10919711
ENSG00000116062 MSH6 tumors 10934138
ENSG00000116062 MSH6 cancer 10954253
ENSG00000116062 MSH6 tumour 10959092
ENSG00000116062 MSH6 tumors 11012981
ENSG00000116062 MSH6 colorectal cancer 11048711
ENSG00000116062 MSH6 tumour 11054716
ENSG00000116062 MSH6 cancer 11062157
ENSG00000116062 MSH6 tumor 11084429
ENSG00000116062 MSH6 breast cancer 11136970
ENSG00000116062 MSH6 tumor 11151427
ENSG00000116062 MSH6 primary cancers 11153917
ENSG00000116062 MSH6 tumors 11196187
ENSG00000116062 MSH6 cervical cancer 11240745
ENSG00000116062 MSH6 colon cancer 11245474
ENSG00000116062 MSH6 tumor 11291077
ENSG00000116062 MSH6 cancers 11302343
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 11306449
ENSG00000116062 MSH6 tumors 11306499
ENSG00000116062 MSH6 colorectal cancer 11333868
ENSG00000116062 MSH6 colorectal cancers 11336166
ENSG00000116062 MSH6 colorectal cancers 11339660
ENSG00000116062 MSH6 tumors 11389088
ENSG00000116062 MSH6 breast cancer 11435612
ENSG00000116062 MSH6 prostate cancer 11444857
ENSG00000116062 MSH6 cancers 11470537
ENSG00000116062 MSH6 ovarian cancer 11477138
ENSG00000116062 MSH6 tumours 11506498
ENSG00000116062 MSH6 tumors 11524701
ENSG00000116062 MSH6 tumor 11532193
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 11561760
ENSG00000116062 MSH6 tumours 11593433
ENSG00000116062 MSH6 tumor 11691815
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 11709755
ENSG00000116062 MSH6 tumor 11742074
ENSG00000116062 MSH6 tumors 11801550
ENSG00000116062 MSH6 colorectal cancer 11807791
ENSG00000116062 MSH6 tumor 11819821
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 11830542
ENSG00000116062 MSH6 tumors 11851879
ENSG00000116062 MSH6 familial colorectal cancer 11900875
ENSG00000116062 MSH6 colon cancer 11971198
ENSG00000116062 MSH6 tumor 11979558
ENSG00000116062 MSH6 tumor 11996796
ENSG00000116062 MSH6 tumors 12015776
ENSG00000116062 MSH6 colorectal cancer 12019211
ENSG00000116062 MSH6 colon cancer 12036916
ENSG00000116062 MSH6 tumor 12057899
ENSG00000116062 MSH6 cancer 12124176
ENSG00000116062 MSH6 tumors 12124320
ENSG00000116062 MSH6 cancers 12124347
ENSG00000116062 MSH6 tumours 12168066
ENSG00000116062 MSH6 hematological cancer 12173046
ENSG00000116062 MSH6 cancers 12177776
ENSG00000116062 MSH6 colon cancer 12231545
ENSG00000116062 MSH6 tumours 12373605
ENSG00000116062 MSH6 ovarian cancer 12376742
ENSG00000116062 MSH6 tumors 12460887
ENSG00000116062 MSH6 colorectal cancer 12469183
ENSG00000116062 MSH6 colon cancer 12522549
ENSG00000116062 MSH6 endometrial cancer 12537658
ENSG00000116062 MSH6 tumors 12547705
ENSG00000116062 MSH6 tumours 12555992
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 12595050
ENSG00000116062 MSH6 endometrial cancer 12649668
ENSG00000116062 MSH6 colorectal cancer 12651806
ENSG00000116062 MSH6 colorectal cancer 12694232
ENSG00000116062 MSH6 Hereditary nonpolyposis colorectal cancer (HNPCC) 12702580
ENSG00000116062 MSH6 tumors 12712438
ENSG00000116062 MSH6 cancer 12714694
ENSG00000116062 MSH6 endometrial cancers 12732731
ENSG00000116062 MSH6 tumor 12756300
ENSG00000116062 MSH6 tumor 12792735
ENSG00000116062 MSH6 tumors 12800209
ENSG00000116062 MSH6 breast cancer 12851690
ENSG00000116062 MSH6 tumors 12861059
ENSG00000116062 MSH6 colorectal cancer 12907901
ENSG00000116062 MSH6 tumor 12910497
ENSG00000116062 MSH6 colorectal cancer 12920072
ENSG00000116062 MSH6 endometrial tumors 12938096
ENSG00000116062 MSH6 lung cancer 12964016
ENSG00000116062 MSH6 breast cancer 12964942
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 14512394
ENSG00000116062 MSH6 colorectal tumors 14518068
ENSG00000116062 MSH6 cancer 14518071
ENSG00000116062 MSH6 colorectal cancer 14520694
ENSG00000116062 MSH6 tumors 14522894
ENSG00000116062 MSH6 Hereditary nonpolyposis colorectal cancer (HNPCC) 14572584
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 14574004
ENSG00000116062 MSH6 colorectal cancer 14574174
ENSG00000116062 MSH6 tumors 14601090
ENSG00000116062 MSH6 tumours 14645346
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 14645426
ENSG00000116062 MSH6 tumors 14652751
ENSG00000116062 MSH6 prostate cancer 14662770
ENSG00000116062 MSH6 breast cancer 14680484
ENSG00000116062 MSH6 Tumors 14732226
ENSG00000116062 MSH6 breast tumors 14747462
ENSG00000116062 MSH6 cancer 14752278
ENSG00000116062 MSH6 cancers 14760069
ENSG00000116062 MSH6 duodenal cancer 14762794
ENSG00000116062 MSH6 colon cancer 14767555
ENSG00000116062 MSH6 tumor 14871813
ENSG00000116062 MSH6 primary cancers 14961575
ENSG00000116062 MSH6 tumor 14974087
ENSG00000116062 MSH6 Tumors 15098177
ENSG00000116062 MSH6 tumors 15118395
ENSG00000116062 MSH6 breast cancer 15169882
ENSG00000116062 MSH6 Tumor 15217520
ENSG00000116062 MSH6 breast cancer 15225781
ENSG00000116062 MSH6 Cancer 15236168
ENSG00000116062 MSH6 endometrial tumors 15238104
ENSG00000116062 MSH6 pancreatic cancer 15264268
ENSG00000116062 MSH6 colorectal cancer 15289847
ENSG00000116062 MSH6 tumours 15294875
ENSG00000116062 MSH6 breast cancer 15313931
ENSG00000116062 MSH6 tumors 15324697
ENSG00000116062 MSH6 rectal cancer 15340263
ENSG00000116062 MSH6 tumors 15350299
ENSG00000116062 MSH6 tumour 15354210
ENSG00000116062 MSH6 colorectal cancer 15365995
ENSG00000116062 MSH6 tumor 15481721
ENSG00000116062 MSH6 colorectal cancer 15483016
ENSG00000116062 MSH6 breast cancer 15528270
ENSG00000116062 MSH6 tumors 15547740
ENSG00000116062 MSH6 breast cancer 15550471
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 15571801
ENSG00000116062 MSH6 breast cancer 15583795
ENSG00000116062 MSH6 tumors 15613860
ENSG00000116062 MSH6 tumors 15619218
ENSG00000116062 MSH6 gastric cancers 15640064
ENSG00000116062 MSH6 colorectal cancers 15660526
ENSG00000116062 MSH6 colorectal cancer 15680406
ENSG00000116062 MSH6 tumors 15692793
ENSG00000116062 MSH6 colorectal cancer 15713769
ENSG00000116062 MSH6 tumors 15740628
ENSG00000116062 MSH6 Tumors 15749237
ENSG00000116062 MSH6 tumors 15782118
ENSG00000116062 MSH6 colorectal cancer 15788665
ENSG00000116062 MSH6 breast cancer 15805151
ENSG00000116062 MSH6 tumour 15834612
ENSG00000116062 MSH6 tumors 15837969
ENSG00000116062 MSH6 tumor 15855819
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 15872200
ENSG00000116062 MSH6 breast cancer 15917309
ENSG00000116062 MSH6 tumors 15918183
ENSG00000116062 MSH6 prostate cancer 15919721
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 15942939
ENSG00000116062 MSH6 tumors 15943554
ENSG00000116062 MSH6 tumour 15963139
ENSG00000116062 MSH6 colorectal cancer 16000562
ENSG00000116062 MSH6 Tumor 16034045
ENSG00000116062 MSH6 colon cancer 16042583
ENSG00000116062 MSH6 prostate cancer 16061635
ENSG00000116062 MSH6 cancers 16106253
ENSG00000116062 MSH6 tumors 16116158
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 16136382
ENSG00000116062 MSH6 tumor 16152605
ENSG00000116062 MSH6 Tumor 16166421
ENSG00000116062 MSH6 breast cancer 16166451
ENSG00000116062 MSH6 cancers 16177963
ENSG00000116062 MSH6 Tumors 16203774
ENSG00000116062 MSH6 hereditary nonpolyposis colon cancer 16237223
ENSG00000116062 MSH6 colorectal cancer 16270383
ENSG00000116062 MSH6 cancers 16283678
ENSG00000116062 MSH6 cancer 16283884
ENSG00000116062 MSH6 tumor 16311127
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 16327991
ENSG00000116062 MSH6 colorectal cancer 16341806
ENSG00000116062 MSH6 ovarian cancer 16361634
ENSG00000116062 MSH6 Tumor 16372347
ENSG00000116062 MSH6 prostate cancer 16388502
ENSG00000116062 MSH6 cancer 16408224
ENSG00000116062 MSH6 brain tumor 16418736
ENSG00000116062 MSH6 familial colorectal cancer 16472587
ENSG00000116062 MSH6 tumours 16497872
ENSG00000116062 MSH6 cancer 16511680
ENSG00000116062 MSH6 cancer 16525781
ENSG00000116062 MSH6 tumor 16618716
ENSG00000116062 MSH6 tumours 16636019
ENSG00000116062 MSH6 tumor 16676398
ENSG00000116062 MSH6 cancer 16721747
ENSG00000116062 MSH6 colon cancer 16721813
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 16771955
ENSG00000116062 MSH6 ovarian cancer 16774946
ENSG00000116062 MSH6 tumors 16784982
ENSG00000116062 MSH6 tumors 16817031
ENSG00000116062 MSH6 skin tumors 16826164
ENSG00000116062 MSH6 familial colorectal cancer 16835336
ENSG00000116062 MSH6 tumors 16837128
ENSG00000116062 MSH6 breast cancer 16877447
ENSG00000116062 MSH6 ovarian cancer 16879751
ENSG00000116062 MSH6 tumors 16885347
ENSG00000116062 MSH6 tumors 16885385
ENSG00000116062 MSH6 colorectal cancers 16890597
ENSG00000116062 MSH6 colorectal cancer 16902769
ENSG00000116062 MSH6 breast cancer 16938873
ENSG00000116062 MSH6 colorectal cancer 16940983
ENSG00000116062 MSH6 colon cancer 16963262
ENSG00000116062 MSH6 Breast Cancer 16980945
ENSG00000116062 MSH6 tumours 16996262
ENSG00000116062 MSH6 tumor 16996571
ENSG00000116062 MSH6 endometrial cancer 17003396
ENSG00000116062 MSH6 tumour 17034469
ENSG00000116062 MSH6 tumour 17039270
ENSG00000116062 MSH6 tumours 17072825
ENSG00000116062 MSH6 cancer 17101317
ENSG00000116062 MSH6 breast cancer 17108143
ENSG00000116062 MSH6 colorectal cancer 17117178
ENSG00000116062 MSH6 colorectal cancer 17205513
ENSG00000116062 MSH6 tumors 17284719
ENSG00000116062 MSH6 tumors 17312306
ENSG00000116062 MSH6 endometrial cancer 17327285
ENSG00000116062 MSH6 breast cancer 17332282
ENSG00000116062 MSH6 tumors 17343610
ENSG00000116062 MSH6 cancer 17347989
ENSG00000116062 MSH6 cancer 17348456
ENSG00000116062 MSH6 colorectal cancer 17392593
ENSG00000116062 MSH6 tumors 17394628
ENSG00000116062 MSH6 breast cancer 17395694
ENSG00000116062 MSH6 tumor 17404084
ENSG00000116062 MSH6 colon cancer 17417778
ENSG00000116062 MSH6 tumour 17453009
ENSG00000116062 MSH6 tumour 17454753
ENSG00000116062 MSH6 uterine cancer 17466051
ENSG00000116062 MSH6 tumors 17504984
ENSG00000116062 MSH6 Ewing tumors 17530287
ENSG00000116062 MSH6 colorectal cancer 17582678
ENSG00000116062 MSH6 Hereditary nonpolyposis colorectal cancer (HNPCC) 17594722
ENSG00000116062 MSH6 colorectal cancer 17613544
ENSG00000116062 MSH6 tumors 17652638
ENSG00000116062 MSH6 colorectal cancer 17661183
ENSG00000116062 MSH6 bladder cancer 17676485
ENSG00000116062 MSH6 tumor 17718861
ENSG00000116062 MSH6 colorectal cancer 17854147
ENSG00000116062 MSH6 colon cancer 17920897
ENSG00000116062 MSH6 Tumor 17925543
ENSG00000116062 MSH6 Colorectal Cancer 17935271
ENSG00000116062 MSH6 colorectal cancer 17939062
ENSG00000116062 MSH6 colorectal cancer 17942459
ENSG00000116062 MSH6 ovarian cancer 17950381
ENSG00000116062 MSH6 tumors 17950544
ENSG00000116062 MSH6 tumors 17968310
ENSG00000116062 MSH6 tumor 17973265
ENSG00000116062 MSH6 tumors 18006922
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 18030674
ENSG00000116062 MSH6 tumors 18051230
ENSG00000116062 MSH6 tumours 18053027
ENSG00000116062 MSH6 breast cancer 18059336
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 18067074
ENSG00000116062 MSH6 ovarian cancers 18177052
ENSG00000116062 MSH6 tumors 18192567
ENSG00000116062 MSH6 colorectal cancer 18214062
ENSG00000116062 MSH6 tumours 18236172
ENSG00000116062 MSH6 tumors 18254781
ENSG00000116062 MSH6 endometrial cancer 18269114
ENSG00000116062 MSH6 prostate cancer 18355840
ENSG00000116062 MSH6 colorectal cancer 18409202
ENSG00000116062 MSH6 tumors 18415027
ENSG00000116062 MSH6 colorectal cancer 18417481
ENSG00000116062 MSH6 colon cancer 18464258
ENSG00000116062 MSH6 ovarian cancer 18469706
ENSG00000116062 MSH6 childhood cancer 18481196
ENSG00000116062 MSH6 colorectal cancer 18484749
ENSG00000116062 MSH6 tumors 18521406
ENSG00000116062 MSH6 colon cancer 18523027
ENSG00000116062 MSH6 tumor 18554553
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 18556776
ENSG00000116062 MSH6 breast cancer 18561318
ENSG00000116062 MSH6 endometrial cancers 18624996
ENSG00000116062 MSH6 colorectal cancer 18636359
ENSG00000116062 MSH6 breast cancers 18673534
ENSG00000116062 MSH6 colorectal cancers 18677806
ENSG00000116062 MSH6 cancers 18679418
ENSG00000116062 MSH6 breast cancer 18701435
ENSG00000116062 MSH6 cancer 18709565
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 18713544
ENSG00000116062 MSH6 ovarian cancer 18723338
ENSG00000116062 MSH6 prostate cancer 18780293
ENSG00000116062 MSH6 tumours 18781192
ENSG00000116062 MSH6 tumour 18781619
ENSG00000116062 MSH6 ovarian cancer 18787632
ENSG00000116062 MSH6 cancer 18790734
ENSG00000116062 MSH6 breast cancer 18827493
ENSG00000116062 MSH6 cancer 18832373
ENSG00000116062 MSH6 endometrial cancer 18841495
ENSG00000116062 MSH6 colorectal cancer 18851982
ENSG00000116062 MSH6 tumor 18936790
ENSG00000116062 MSH6 tumor 18951447
ENSG00000116062 MSH6 cancer 18951449
ENSG00000116062 MSH6 endometrial cancer 18972272
ENSG00000116062 MSH6 tumor 19054153
ENSG00000116062 MSH6 tumours 19072991
ENSG00000116062 MSH6 breast cancer 19095746
ENSG00000116062 MSH6 Tumor 19101824
ENSG00000116062 MSH6 tumor 19154585
ENSG00000116062 MSH6 colorectal cancer 19173809
ENSG00000116062 MSH6 tumors 19179424
ENSG00000116062 MSH6 gastric cancer 19181186
ENSG00000116062 MSH6 inherited cancer syndromes 19244167
ENSG00000116062 MSH6 colon cancer 19250818
ENSG00000116062 MSH6 tumors 19265614
ENSG00000116062 MSH6 breast cancer 19276281
ENSG00000116062 MSH6 Tumors 19289622
ENSG00000116062 MSH6 childhood cancer 19293170
ENSG00000116062 MSH6 tumor 19342947
ENSG00000116062 MSH6 cancer 19381960
ENSG00000116062 MSH6 cancer 19389263
ENSG00000116062 MSH6 tumour 19398597
ENSG00000116062 MSH6 breast cancer 19418218
ENSG00000116062 MSH6 tumor 19455606
ENSG00000116062 MSH6 breast cancer 19456271
ENSG00000116062 MSH6 endometrial cancers 19492230
ENSG00000116062 MSH6 endometrial cancer 19515405
ENSG00000116062 MSH6 colorectal cancer 19526325
ENSG00000116062 MSH6 tumors 19551857
ENSG00000116062 MSH6 tumors 19575290
ENSG00000116062 MSH6 colon cancer 19582761
ENSG00000116062 MSH6 cancer 19584161
ENSG00000116062 MSH6 ovarian cancer 19635727
ENSG00000116062 MSH6 colorectal cancer 19685280
ENSG00000116062 MSH6 colorectal cancer 19685281
ENSG00000116062 MSH6 tumors 19690142
ENSG00000116062 MSH6 tumours 19697156
ENSG00000116062 MSH6 cancer 19701241
ENSG00000116062 MSH6 tumour 19706203
ENSG00000116062 MSH6 colorectal cancer 19707776
ENSG00000116062 MSH6 endometrial cancers 19723918
ENSG00000116062 MSH6 inherited cancer syndrome 19728162
ENSG00000116062 MSH6 colorectal cancer 19752738
ENSG00000116062 MSH6 familial breast cancer 19781088
ENSG00000116062 MSH6 cancer 19787250
ENSG00000116062 MSH6 cancer 19793570
ENSG00000116062 MSH6 cancer 19794885
ENSG00000116062 MSH6 tumour 19804606
ENSG00000116062 MSH6 cancer 19821155
ENSG00000116062 MSH6 tumors 19851887
ENSG00000116062 MSH6 tumors 19898223
ENSG00000116062 MSH6 familial breast cancer 19924528
ENSG00000116062 MSH6 tumour 19929944
ENSG00000116062 MSH6 hereditary colorectal cancer 19949877
ENSG00000116062 MSH6 tumor 20005439
ENSG00000116062 MSH6 Cancer 20028567
ENSG00000116062 MSH6 cancers 20028993
ENSG00000116062 MSH6 cancer 20149637
ENSG00000116062 MSH6 endometrial cancer 20153885
ENSG00000116062 MSH6 tumours 20160730
ENSG00000116062 MSH6 tumors 20195377
ENSG00000116062 MSH6 Tumor 20215533
ENSG00000116062 MSH6 colorectal cancer 20228021
ENSG00000116062 MSH6 cancer 20374707
ENSG00000116062 MSH6 tumor 20379851
ENSG00000116062 MSH6 ovarian cancer 20386703
ENSG00000116062 MSH6 colorectal cancers 20395525
ENSG00000116062 MSH6 cancer 20396392
ENSG00000116062 MSH6 tumor 20417090
ENSG00000116062 MSH6 tumours 20417091
ENSG00000116062 MSH6 breast cancer 20442283
ENSG00000116062 MSH6 Tumour 20459533
ENSG00000116062 MSH6 cancer 20473912
ENSG00000116062 MSH6 cancer 20487569
ENSG00000116062 MSH6 colorectal cancers 20495086
ENSG00000116062 MSH6 cancer 20495087
ENSG00000116062 MSH6 tumors 20516444
ENSG00000116062 MSH6 tumor 20552889
ENSG00000116062 MSH6 tumors 20565851
ENSG00000116062 MSH6 tumor 20567595
ENSG00000116062 MSH6 cancers 20587412
ENSG00000116062 MSH6 cancer 20591884
ENSG00000116062 MSH6 Tumours 20594200
ENSG00000116062 MSH6 colorectal cancers 20632815
ENSG00000116062 MSH6 cancer 20640520
ENSG00000116062 MSH6 tumors 20655395
ENSG00000116062 MSH6 tumor 20704743
ENSG00000116062 MSH6 cancer 20727894
ENSG00000116062 MSH6 cancer 20799711
ENSG00000116062 MSH6 colon cancers 20844976
ENSG00000116062 MSH6 DLBCL 20846793
ENSG00000116062 MSH6 endometrial cancer 20850175
ENSG00000116062 MSH6 tumours 20877357
ENSG00000116062 MSH6 colorectal cancer 20924129
ENSG00000116062 MSH6 colorectal cancer 20937110
ENSG00000116062 MSH6 colorectal cancer 20979647
ENSG00000116062 MSH6 breast cancer 21059860
ENSG00000116062 MSH6 colon cancer 21075794
ENSG00000116062 MSH6 Tumours 21081928
ENSG00000116062 MSH6 tumors 21107085
ENSG00000116062 MSH6 tumor 21120944
ENSG00000116062 MSH6 gastric cancer 21136174
ENSG00000116062 MSH6 endometrial cancer 21145788
ENSG00000116062 MSH6 endometrial cancer 21155762
ENSG00000116062 MSH6 cancer 21227399
ENSG00000116062 MSH6 invasive breast cancers 21228925
ENSG00000116062 MSH6 tumor 21232179
ENSG00000116062 MSH6 tumor 21233718
ENSG00000116062 MSH6 tumours 21261604
ENSG00000116062 MSH6 GBM 21288634
ENSG00000116062 MSH6 gastrointestinal tract cancers 21297438
ENSG00000116062 MSH6 colorectal cancer 21334712
ENSG00000116062 MSH6 hereditary diffuse gastric cancer 21348412
ENSG00000116062 MSH6 cancers 21375527
ENSG00000116062 MSH6 Tumor 21386990
ENSG00000116062 MSH6 tumor 21389894
ENSG00000116062 MSH6 breast cancer 21390497
ENSG00000116062 MSH6 cancer 21436632
ENSG00000116062 MSH6 cancer 21437237
ENSG00000116062 MSH6 Tumor 21464009
ENSG00000116062 MSH6 colorectal cancer 21475916
ENSG00000116062 MSH6 tumors 21499234
ENSG00000116062 MSH6 cancer 21501865
ENSG00000116062 MSH6 tumours 21514719
ENSG00000116062 MSH6 cervical cancer 21541570
ENSG00000116062 MSH6 colon cancer 21570414
ENSG00000116062 MSH6 mesenchymal tumor 21572397
ENSG00000116062 MSH6 cancer 21636617
ENSG00000116062 MSH6 tumor 21637783
ENSG00000116062 MSH6 Cancer 21642682
ENSG00000116062 MSH6 tumors 21645411
ENSG00000116062 MSH6 colorectal cancers 21651356
ENSG00000116062 MSH6 brain tumors 21674763
ENSG00000116062 MSH6 pancreatic cancer 21681824
ENSG00000116062 MSH6 gastric cancers 21687951
ENSG00000116062 MSH6 breast cancer 21700777
ENSG00000116062 MSH6 invasive breast cancer 21710692
ENSG00000116062 MSH6 cancers 21769135
ENSG00000116062 MSH6 endometrial cancer 21791569
ENSG00000116062 MSH6 tumors 21819606
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 21821902
ENSG00000116062 MSH6 colorectal cancer 21836479
ENSG00000116062 MSH6 cancer 21837758
ENSG00000116062 MSH6 tumours 21868491
ENSG00000116062 MSH6 prostate cancer 21886458
ENSG00000116062 MSH6 colon cancer 21911971
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 21937421
ENSG00000116062 MSH6 colorectal cancer 21938565
ENSG00000116062 MSH6 breast cancers 21949547
ENSG00000116062 MSH6 tumor 21997695
ENSG00000116062 MSH6 tumours 22000951
ENSG00000116062 MSH6 breast cancer 22002538
ENSG00000116062 MSH6 breast cancer 22035181
ENSG00000116062 MSH6 tumor 22067334
ENSG00000116062 MSH6 tumours 22120844
ENSG00000116062 MSH6 pediatric germ cell tumors 22147429
ENSG00000116062 MSH6 tumors 22164924
ENSG00000116062 MSH6 tumors 22189970
ENSG00000116062 MSH6 pancreatic cancer 22219001
ENSG00000116062 MSH6 colorectal cancer 22234272
ENSG00000116062 MSH6 gynecologic tumors 22247799
ENSG00000116062 MSH6 tumors 22249440
ENSG00000116062 MSH6 cancer 22277660
ENSG00000116062 MSH6 hereditary colorectal cancer 22283331
ENSG00000116062 MSH6 colorectal cancer 22287190
ENSG00000116062 MSH6 breast cancer 22307791
ENSG00000116062 MSH6 Colon Cancer 22331944
ENSG00000116062 MSH6 ovarian cancers 22361722
ENSG00000116062 MSH6 Tumor 22395473
ENSG00000116062 MSH6 cancer 22454054
ENSG00000116062 MSH6 cancers 22476430
ENSG00000116062 MSH6 colon cancer 22484182
ENSG00000116062 MSH6 cancer 22493294
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 22495361
ENSG00000116062 MSH6 tumor 22547953
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ENSG00000116062 MSH6 tumor 30861589
ENSG00000116062 MSH6 tumor 30863719
ENSG00000116062 MSH6 cancer 30864976
ENSG00000116062 MSH6 tumor 30867843
ENSG00000116062 MSH6 tumors 30869569
ENSG00000116062 MSH6 ureter cancer 30882153
ENSG00000116062 MSH6 tumor 30889380
ENSG00000116062 MSH6 tumors 30916491
ENSG00000116062 MSH6 tumor 30918358
ENSG00000116062 MSH6 colorectal cancers 30918532
ENSG00000116062 MSH6 endometrial cancers 30926882
ENSG00000116062 MSH6 cancer 30974197
ENSG00000116062 MSH6 tumors 30983459
ENSG00000116062 MSH6 tumour 31023277
ENSG00000116062 MSH6 cancer 31028081
ENSG00000116062 MSH6 tumor 31046843
ENSG00000116062 MSH6 tumor 31056861
ENSG00000116062 MSH6 tumor 31068195
ENSG00000116062 MSH6 Tumor 31080553
ENSG00000116062 MSH6 lung cancers 31092773
ENSG00000116062 MSH6 endometrial cancer 31100584
ENSG00000116062 MSH6 tumor 31104363
ENSG00000116062 MSH6 colorectal cancer 31116002
ENSG00000116062 MSH6 tumor 31116268
ENSG00000116062 MSH6 tumors 31116423
ENSG00000116062 MSH6 colorectal cancer 31204389
ENSG00000116062 MSH6 prostate cancer 31209634
ENSG00000116062 MSH6 tumours 31210809
ENSG00000116062 MSH6 colorectal tumors 31220642
ENSG00000116062 MSH6 tumours 31231557
ENSG00000116062 MSH6 tumour 31235541
ENSG00000116062 MSH6 tumor 31248416
ENSG00000116062 MSH6 tumors 31263894
ENSG00000116062 MSH6 cancer 31273487
ENSG00000116062 MSH6 Cancer 31273614
ENSG00000116062 MSH6 tumors 31278255
ENSG00000116062 MSH6 tumors 31292272
ENSG00000116062 MSH6 skin tumors 31292797
ENSG00000116062 MSH6 lung cancer 31297337
ENSG00000116062 MSH6 tumor 31307542
ENSG00000116062 MSH6 tumor 31307558
ENSG00000116062 MSH6 gastric cancer 31319185
ENSG00000116062 MSH6 colorectal cancer 31337882
ENSG00000116062 MSH6 tumor 31341365
ENSG00000116062 MSH6 tumor 31360876
ENSG00000116062 MSH6 prostate cancer 31366128
ENSG00000116062 MSH6 ovarian cancer 31366178
ENSG00000116062 MSH6 cancer 31374908
ENSG00000116062 MSH6 cancer 31386297
ENSG00000116062 MSH6 cancers 31391288
ENSG00000116062 MSH6 colon cancer 31410062
ENSG00000116062 MSH6 Cancer 31417532
ENSG00000116062 MSH6 colorectal cancer 31433215
ENSG00000116062 MSH6 endometrial cancer 31469860
ENSG00000116062 MSH6 GBMs 31480372
ENSG00000116062 MSH6 tumors 31497750
ENSG00000116062 MSH6 childhood cancer 31501241
ENSG00000116062 MSH6 oral cancer 31502267
ENSG00000116062 MSH6 breast cancers 31522348
ENSG00000116062 MSH6 tumors 31548566
ENSG00000116062 MSH6 Colon Cancer 31551580
ENSG00000116062 MSH6 cancer 31554352
ENSG00000116062 MSH6 Tumour 31555481
ENSG00000116062 MSH6 tumor 31567138
ENSG00000116062 MSH6 tumor 31601699
ENSG00000116062 MSH6 Tumor 31604779
ENSG00000116062 MSH6 colorectal cancers 31606263
ENSG00000116062 MSH6 tumor 31614500
ENSG00000116062 MSH6 tumor 31618962
ENSG00000116062 MSH6 tumor 31624068
ENSG00000116062 MSH6 colon cancer 31636762
ENSG00000116062 MSH6 colorectal cancers 31649038
ENSG00000116062 MSH6 breast cancer 31658756
ENSG00000116062 MSH6 colorectal cancer 31660093
ENSG00000116062 MSH6 tumors 31665498
ENSG00000116062 MSH6 tumour 31677289
ENSG00000116062 MSH6 tumour 31703605
ENSG00000116062 MSH6 colorectal cancers 31745674
ENSG00000116062 MSH6 bladder cancer 31766169
ENSG00000116062 MSH6 tumor 31783044
ENSG00000116062 MSH6 GBM 31810938
ENSG00000116062 MSH6 prostate cancers 31811435
ENSG00000116062 MSH6 tumor 31814971
ENSG00000116062 MSH6 Wilms Tumor 31815888
ENSG00000116062 MSH6 Colorectal cancer 31845022
ENSG00000116062 MSH6 cancer 31848314
ENSG00000116062 MSH6 familial pancreatic cancer 31851094
ENSG00000116062 MSH6 colorectal cancer 31889830
ENSG00000116062 MSH6 cancers 31896172
ENSG00000116062 MSH6 Tumors 31898331
ENSG00000116062 MSH6 GBM 31900275
ENSG00000116062 MSH6 tumors 31916017
ENSG00000116062 MSH6 Tumors 31926173
ENSG00000116062 MSH6 endometrial cancer 31932681
ENSG00000116062 MSH6 tumor 31933757
ENSG00000116062 MSH6 colorectal cancer 31949824
ENSG00000116062 MSH6 tumors 31958127
ENSG00000116062 MSH6 tumors 31958182
ENSG00000116062 MSH6 cancer 31965077
ENSG00000116062 MSH6 tumors 6287020
ENSG00000116062 MSH6 tumor 7604264
ENSG00000116062 MSH6 cancer 8600025
ENSG00000116062 MSH6 tumours 8782829
ENSG00000116062 MSH6 colorectal cancer 8805365
ENSG00000116062 MSH6 tumor 8984198
ENSG00000116062 MSH6 cancer 9054582
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 9218993
ENSG00000116062 MSH6 tumor 9230208
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 9307272
ENSG00000116062 MSH6 tumor 9307278
ENSG00000116062 MSH6 colon tumors 9331106
ENSG00000116062 MSH6 tumor 9349506
ENSG00000116062 MSH6 cancer 9390556
ENSG00000116062 MSH6 tumors 9401011
ENSG00000116062 MSH6 tumors 9419979
ENSG00000116062 MSH6 hereditary nonpolyposis colon cancer 9491849
ENSG00000116062 MSH6 cancers 9500462
ENSG00000116062 MSH6 tumor 9560383
ENSG00000116062 MSH6 head and neck cancer 9568786
ENSG00000116062 MSH6 colorectal cancer 9592192
ENSG00000116062 MSH6 non-small cell lung cancer 9650548
ENSG00000116062 MSH6 cancer 9671718
ENSG00000116062 MSH6 colorectal tumors 9674699
ENSG00000116062 MSH6 tumor 9677427
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 9709044
ENSG00000116062 MSH6 colorectal cancer 9736731
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer (HNPCC) 9740671
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 9774676
ENSG00000116062 MSH6 gastric cancers 9808525
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 9823302
ENSG00000116062 MSH6 cancers 9824204
ENSG00000116062 MSH6 tumor 9855004
ENSG00000116062 MSH6 colon cancer 9916805
ENSG00000116062 MSH6 hereditary nonpolyposis colorectal cancer 9929971
ENSG00000116062 MSH6 tumors PMC2736982
ENSG00000116062 MSH6 tumours PMC2838404
ENSG00000116062 MSH6 cancer PMC2840013
ENSG00000116062 MSH6 cancer PMC4669990
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000116062 MSH6 gastric adenocarcinoma missense_variant 4.821% (54/1120) 3 entries
ENSG00000116062 MSH6 colon adenocarcinoma frameshift_variant 5.085% (75/1475) 9 entries
ENSG00000116062 MSH6 endometrial carcinoma frameshift_variant 10.45% (21/201) 3 entries
ENSG00000116062 MSH6 colorectal adenocarcinoma frameshift_variant 9.648% (189/1959) 14 entries
ENSG00000116062 MSH6 colorectal adenocarcinoma sequence_alteration 9.648% (189/1959) 8 entries
ENSG00000116062 MSH6 cecum adenocarcinoma sequence_alteration 7.792% (24/308) 6 entries
ENSG00000116062 MSH6 Duodenal Adenocarcinoma frameshift_variant 24.0% (6/25) 2 entries
ENSG00000116062 MSH6 endometrial carcinoma sequence_alteration 10.45% (21/201) 1 entry
ENSG00000116062 MSH6 cecum adenocarcinoma frameshift_variant 7.792% (24/308) 4 entries
ENSG00000116062 MSH6 colorectal adenocarcinoma stop_gained 9.648% (189/1959) 6 entries
ENSG00000116062 MSH6 gastric adenocarcinoma frameshift_variant 4.821% (54/1120) 3 entries
ENSG00000116062 MSH6 colon adenocarcinoma stop_gained 5.085% (75/1475) 2 entries
ENSG00000116062 MSH6 colorectal adenocarcinoma missense_variant 9.648% (189/1959) 9 entries
ENSG00000116062 MSH6 hemangioblastoma missense_variant 20.0% (7/35) 1 entry
ENSG00000116062 MSH6 cecum adenocarcinoma missense_variant 7.792% (24/308) 5 entries
ENSG00000116062 MSH6 cecum adenocarcinoma stop_gained 7.792% (24/308) 3 entries
ENSG00000116062 MSH6 colon adenocarcinoma missense_variant 5.085% (75/1475) 8 entries
ENSG00000116062 MSH6 hemangioblastoma sequence_alteration 20.0% (7/35) 1 entry
ENSG00000116062 MSH6 colon adenocarcinoma sequence_alteration 5.085% (75/1475) 10 entries
ENSG00000116062 MSH6 gastric adenocarcinoma sequence_alteration 4.821% (54/1120) 4 entries
ENSG00000116062 MSH6 endometrial carcinoma stop_gained 10.45% (21/201) 1 entry
ENSG00000116062 MSH6 endometrial carcinoma missense_variant 10.45% (21/201) 2 entries
ENSG00000116062 MSH6 female breast carcinoma sequence_alteration 1.188% (5/421) 5 entries
ENSG00000116062 MSH6 gastric intestinal type adenocarcinoma missense_variant 2.632% (4/152) 2 entries
ENSG00000116062 MSH6 diffuse large B-cell lymphoma missense_variant 0.7576% (3/396) 2 entries
ENSG00000116062 MSH6 esophageal adenocarcinoma sequence_alteration 2.559% (14/547) 1 entry
ENSG00000116062 MSH6 pancreatic ductal adenocarcinoma sequence_alteration 1.101% (19/1726) 2 entries
ENSG00000116062 MSH6 breast carcinoma sequence_alteration 0.7952% (12/1509) 1 entry
ENSG00000116062 MSH6 B-cell acute lymphoblastic leukemia missense_variant 0.6711% (2/298) 1 entry
ENSG00000116062 MSH6 glioma missense_variant 1.488% (10/672) 2 entries
ENSG00000116062 MSH6 skin melanoma stop_gained 2.154% (26/1207) 5 entries
ENSG00000116062 MSH6 bladder transitional cell carcinoma missense_variant 2.603% (12/461) 2 entries
ENSG00000116062 MSH6 anaplastic oligodendroglioma missense_variant 7.692% (7/91) 3 entries
ENSG00000116062 MSH6 prostate adenocarcinoma sequence_alteration 1.117% (25/2238) 4 entries
ENSG00000116062 MSH6 glioma stop_gained 1.488% (10/672) 2 entries
ENSG00000116062 MSH6 esophageal adenocarcinoma frameshift_variant 2.559% (14/547) 2 entries
ENSG00000116062 MSH6 Merkel cell skin cancer missense_variant 2.151% (2/93) 1 entry
ENSG00000116062 MSH6 rectal adenocarcinoma frameshift_variant 2.222% (13/585) 2 entries
ENSG00000116062 MSH6 endometrium adenocarcinoma sequence_alteration 8.411% (9/107) 2 entries
ENSG00000116062 MSH6 skin melanoma missense_variant 2.154% (26/1207) 6 entries
ENSG00000116062 MSH6 rectal adenocarcinoma sequence_alteration 2.222% (13/585) 3 entries
ENSG00000116062 MSH6 skin carcinoma sequence_alteration 2.885% (3/104) 1 entry
ENSG00000116062 MSH6 Uterine Carcinosarcoma sequence_alteration 3.398% (7/206) 2 entries
ENSG00000116062 MSH6 endometrium adenocarcinoma frameshift_variant 8.411% (9/107) 2 entries
ENSG00000116062 MSH6 bladder transitional cell carcinoma sequence_alteration 2.603% (12/461) 2 entries
ENSG00000116062 MSH6 Gallbladder Adenocarcinoma missense_variant 1.546% (3/194) 2 entries
ENSG00000116062 MSH6 prostate carcinoma missense_variant 1.446% (7/484) 1 entry
ENSG00000116062 MSH6 melanoma sequence_alteration 3.797% (6/158) 2 entries
ENSG00000116062 MSH6 melanoma missense_variant 3.797% (6/158) 2 entries
ENSG00000116062 MSH6 Uterine Carcinosarcoma stop_gained 3.398% (7/206) 1 entry
ENSG00000116062 MSH6 esophageal squamous cell carcinoma missense_variant 2.286% (16/700) 5 entries
ENSG00000116062 MSH6 basal cell carcinoma missense_variant 2.941% (2/68) 2 entries
ENSG00000116062 MSH6 colorectal adenoma frameshift_variant 10.53% (2/19) 2 entries
ENSG00000116062 MSH6 Uterine Carcinosarcoma frameshift_variant 3.398% (7/206) 2 entries
ENSG00000116062 MSH6 small intestinal adenocarcinoma frameshift_variant 13.89% (5/36) 3 entries
ENSG00000116062 MSH6 Endometrial Endometrioid Adenocarcinoma missense_variant 3.995% (35/876) 3 entries
ENSG00000116062 MSH6 small cell lung carcinoma missense_variant 1.114% (5/449) 2 entries
ENSG00000116062 MSH6 metaplastic breast carcinoma missense_variant 3.226% (2/62) 2 entries
ENSG00000116062 MSH6 hepatocellular carcinoma frameshift_variant 1.369% (14/1023) 1 entry
ENSG00000116062 MSH6 hepatocellular carcinoma sequence_alteration 1.369% (14/1023) 1 entry
ENSG00000116062 MSH6 gastric intestinal type adenocarcinoma sequence_alteration 2.632% (4/152) 2 entries
ENSG00000116062 MSH6 prostate adenocarcinoma missense_variant 1.117% (25/2238) 3 entries
ENSG00000116062 MSH6 brain glioblastoma sequence_alteration 2.145% (29/1352) 6 entries
ENSG00000116062 MSH6 breast carcinoma missense_variant 0.7952% (12/1509) 1 entry
ENSG00000116062 MSH6 brain glioblastoma stop_gained 2.145% (29/1352) 3 entries
ENSG00000116062 MSH6 nasopharyngeal squamous cell carcinoma sequence_alteration 1.623% (5/308) 2 entries
ENSG00000116062 MSH6 Endometrial Endometrioid Adenocarcinoma stop_gained 3.995% (35/876) 1 entry
ENSG00000116062 MSH6 non-small cell lung carcinoma missense_variant 2.174% (3/138) 2 entries
ENSG00000116062 MSH6 T-cell acute lymphoblastic leukemia stop_gained 2.243% (17/758) 2 entries
ENSG00000116062 MSH6 Cervical Small Cell Carcinoma sequence_alteration 25.0% (2/8) 1 entry
ENSG00000116062 MSH6 squamous cell lung carcinoma sequence_alteration 1.206% (12/995) 2 entries
ENSG00000116062 MSH6 prostate carcinoma sequence_alteration 1.446% (7/484) 2 entries
ENSG00000116062 MSH6 pancreatic ductal adenocarcinoma stop_gained 1.101% (19/1726) 2 entries
ENSG00000116062 MSH6 large cell lung carcinoma sequence_alteration 10.53% (2/19) 1 entry
ENSG00000116062 MSH6 B-cell acute lymphoblastic leukemia sequence_alteration 0.6711% (2/298) 1 entry
ENSG00000116062 MSH6 urothelial carcinoma sequence_alteration 2.339% (4/171) 2 entries
ENSG00000116062 MSH6 clear cell renal carcinoma missense_variant 0.5569% (9/1616) 1 entry
ENSG00000116062 MSH6 esophageal adenocarcinoma missense_variant 2.559% (14/547) 1 entry
ENSG00000116062 MSH6 female breast carcinoma missense_variant 1.188% (5/421) 4 entries
ENSG00000116062 MSH6 Endometrial Clear Cell Adenocarcinoma missense_variant 4.082% (4/98) 2 entries
ENSG00000116062 MSH6 Endometrial Endometrioid Adenocarcinoma frameshift_variant 3.995% (35/876) 3 entries
ENSG00000116062 MSH6 gastric intestinal type adenocarcinoma frameshift_variant 2.632% (4/152) 1 entry
ENSG00000116062 MSH6 T-cell acute lymphoblastic leukemia frameshift_variant 2.243% (17/758) 3 entries
ENSG00000116062 MSH6 breast ductal adenocarcinoma missense_variant 1.7% (29/1706) 2 entries
ENSG00000116062 MSH6 Endometrial Endometrioid Adenocarcinoma sequence_alteration 3.995% (35/876) 4 entries
ENSG00000116062 MSH6 squamous cell lung carcinoma missense_variant 1.206% (12/995) 2 entries
ENSG00000116062 MSH6 bladder carcinoma sequence_alteration 2.496% (14/561) 1 entry
ENSG00000116062 MSH6 oral squamous cell carcinoma missense_variant 2.652% (7/264) 4 entries
ENSG00000116062 MSH6 bladder carcinoma missense_variant 2.496% (14/561) 1 entry
ENSG00000116062 MSH6 anaplastic astrocytoma missense_variant 2.055% (3/146) 2 entries
ENSG00000116062 MSH6 rectal adenocarcinoma missense_variant 2.222% (13/585) 2 entries
ENSG00000116062 MSH6 diffuse large B-cell lymphoma sequence_alteration 0.7576% (3/396) 3 entries
ENSG00000116062 MSH6 nasopharyngeal squamous cell carcinoma missense_variant 1.623% (5/308) 2 entries
ENSG00000116062 MSH6 head and neck squamous cell carcinoma missense_variant 0.5109% (4/783) 2 entries
ENSG00000116062 MSH6 Gallbladder Adenocarcinoma sequence_alteration 1.546% (3/194) 2 entries
ENSG00000116062 MSH6 oral squamous cell carcinoma sequence_alteration 2.652% (7/264) 4 entries
ENSG00000116062 MSH6 gastric carcinoma sequence_alteration 2.41% (2/83) 1 entry
ENSG00000116062 MSH6 prostate adenocarcinoma frameshift_variant 1.117% (25/2238) 3 entries
ENSG00000116062 MSH6 kidney Wilms tumor sequence_alteration 0.6231% (2/321) 1 entry
ENSG00000116062 MSH6 anaplastic oligodendroglioma sequence_alteration 7.692% (7/91) 3 entries
ENSG00000116062 MSH6 Duodenal Adenocarcinoma missense_variant 24.0% (6/25) 1 entry
ENSG00000116062 MSH6 brain glioblastoma missense_variant 2.145% (29/1352) 5 entries
ENSG00000116062 MSH6 endometrium adenocarcinoma stop_gained 8.411% (9/107) 2 entries
ENSG00000116062 MSH6 non-small cell lung carcinoma sequence_alteration 2.174% (3/138) 2 entries
ENSG00000116062 MSH6 pancreatic ductal adenocarcinoma missense_variant 1.101% (19/1726) 2 entries
ENSG00000116062 MSH6 acute myeloid leukemia missense_variant 0.5263% (6/1140) 2 entries
ENSG00000116062 MSH6 T-cell acute lymphoblastic leukemia missense_variant 2.243% (17/758) 3 entries
ENSG00000116062 MSH6 lobular breast carcinoma sequence_alteration 1.471% (4/272) 1 entry
ENSG00000116062 MSH6 lung adenocarcinoma stop_gained 1.041% (29/2785) 3 entries
ENSG00000116062 MSH6 Merkel cell skin cancer sequence_alteration 2.151% (2/93) 1 entry
ENSG00000116062 MSH6 hepatocellular carcinoma missense_variant 1.369% (14/1023) 1 entry
ENSG00000116062 MSH6 T-cell acute lymphoblastic leukemia sequence_alteration 2.243% (17/758) 4 entries
ENSG00000116062 MSH6 gastric tubular adenocarcinoma frameshift_variant 13.33% (2/15) 1 entry
ENSG00000116062 MSH6 lobular breast carcinoma missense_variant 1.471% (4/272) 2 entries
ENSG00000116062 MSH6 esophageal squamous cell carcinoma sequence_alteration 2.286% (16/700) 5 entries
ENSG00000116062 MSH6 basal cell carcinoma sequence_alteration 2.941% (2/68) 2 entries
ENSG00000116062 MSH6 lung adenocarcinoma sequence_alteration 1.041% (29/2785) 8 entries
ENSG00000116062 MSH6 clear cell renal carcinoma sequence_alteration 0.5569% (9/1616) 2 entries
ENSG00000116062 MSH6 Uterine Carcinosarcoma missense_variant 3.398% (7/206) 2 entries
ENSG00000116062 MSH6 papillary thyroid carcinoma missense_variant 0.4098% (2/488) 1 entry
ENSG00000116062 MSH6 breast ductal adenocarcinoma stop_gained 1.7% (29/1706) 1 entry
ENSG00000116062 MSH6 breast ductal adenocarcinoma sequence_alteration 1.7% (29/1706) 3 entries
ENSG00000116062 MSH6 small cell lung carcinoma sequence_alteration 1.114% (5/449) 2 entries
ENSG00000116062 MSH6 lung adenocarcinoma missense_variant 1.041% (29/2785) 7 entries
ENSG00000116062 MSH6 skin melanoma sequence_alteration 2.154% (26/1207) 4 entries
ENSG00000116062 MSH6 endometrium adenocarcinoma missense_variant 8.411% (9/107) 4 entries
ENSG00000116062 MSH6 Thyroid Gland Undifferentiated (Anaplastic) Carcinoma sequence_alteration 0.7353% (2/272) 2 entries
ENSG00000116062 MSH6 Cervical Small Cell Carcinoma missense_variant 25.0% (2/8) 1 entry
ENSG00000116062 MSH6 glioma sequence_alteration 1.488% (10/672) 1 entry
ENSG00000116062 MSH6 gliosarcoma missense_variant 8.333% (1/12) 1 entry
ENSG00000116062 MSH6 Thyroid Gland Undifferentiated (Anaplastic) Carcinoma stop_gained 0.7353% (2/272) 1 entry
ENSG00000116062 MSH6 ulcerative colitis missense_variant 11.11% (1/9) 1 entry
ENSG00000116062 MSH6 melanoma stop_gained 3.797% (6/158) 1 entry
ENSG00000116062 MSH6 Rectal Tubular Adenoma frameshift_variant 50.0% (1/2) 1 entry
ENSG00000116062 MSH6 Juvenile Xanthogranuloma missense_variant 5.882% (1/17) 1 entry
ENSG00000116062 MSH6 HER2 Positive Breast Carcinoma missense_variant 1.064% (2/188) 1 entry
ENSG00000116062 MSH6 B-cell neoplasm missense_variant 5.556% (1/18) 1 entry
ENSG00000116062 MSH6 Rectal Tubulovillous Adenoma frameshift_variant 25.0% (1/4) 1 entry
ENSG00000116062 MSH6 osteosarcoma missense_variant 1.316% (2/152) 1 entry
ENSG00000116062 MSH6 ovarian adenocarcinoma sequence_alteration 8.333% (1/12) 1 entry
ENSG00000116062 MSH6 brain glioblastoma frameshift_variant 2.145% (29/1352) 1 entry
ENSG00000116062 MSH6 astrocytoma sequence_alteration 33.33% (1/3) 1 entry
ENSG00000116062 MSH6 colon carcinoma frameshift_variant 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 medullary thyroid gland carcinoma missense_variant 2.5% (1/40) 1 entry
ENSG00000116062 MSH6 T-cell acute lymphoblastic leukemia amino_acid_insertion 2.243% (17/758) 1 entry
ENSG00000116062 MSH6 Thymic Undifferentiated Carcinoma missense_variant 16.67% (1/6) 1 entry
ENSG00000116062 MSH6 embryonal rhabdomyosarcoma sequence_alteration 1.163% (1/86) 1 entry
ENSG00000116062 MSH6 colon carcinoma sequence_alteration 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 Endometrial Clear Cell Adenocarcinoma stop_gained 4.082% (4/98) 1 entry
ENSG00000116062 MSH6 adrenocortical adenoma stop_gained 2.439% (1/41) 1 entry
ENSG00000116062 MSH6 Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive frameshift_variant 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 osteosarcoma sequence_alteration 1.316% (2/152) 1 entry
ENSG00000116062 MSH6 angioimmunoblastic T-cell lymphoma sequence_alteration 4.348% (1/23) 1 entry
ENSG00000116062 MSH6 nasopharyngeal squamous cell carcinoma frameshift_variant 1.623% (5/308) 1 entry
ENSG00000116062 MSH6 Placental Choriocarcinoma sequence_alteration 20.0% (1/5) 1 entry
ENSG00000116062 MSH6 anaplastic oligodendroglioma conservative_inframe_deletion 7.692% (7/91) 1 entry
ENSG00000116062 MSH6 Placental Choriocarcinoma missense_variant 20.0% (1/5) 1 entry
ENSG00000116062 MSH6 Atypical Endometrial Hyperplasia frameshift_variant 16.67% (1/6) 1 entry
ENSG00000116062 MSH6 large cell lung carcinoma missense_variant 10.53% (2/19) 1 entry
ENSG00000116062 MSH6 colorectal adenoma sequence_alteration 10.53% (2/19) 1 entry
ENSG00000116062 MSH6 prostate carcinoma frameshift_variant 1.446% (7/484) 1 entry
ENSG00000116062 MSH6 pancreatic ductal adenocarcinoma conservative_inframe_deletion 1.101% (19/1726) 1 entry
ENSG00000116062 MSH6 Appendix Goblet Cell Carcinoid sequence_alteration 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 B-cell acute lymphoblastic leukemia stop_gained 0.6711% (2/298) 1 entry
ENSG00000116062 MSH6 Pleural Epithelioid Mesothelioma missense_variant 0.5025% (1/199) 1 entry
ENSG00000116062 MSH6 Gastrointestinal stromal tumor conservative_inframe_deletion 0.6757% (1/148) 1 entry
ENSG00000116062 MSH6 Thyroid Gland Undifferentiated (Anaplastic) Carcinoma frameshift_variant 0.7353% (2/272) 1 entry
ENSG00000116062 MSH6 hairy cell leukemia missense_variant 4.167% (1/24) 1 entry
ENSG00000116062 MSH6 Thymic Undifferentiated Carcinoma sequence_alteration 16.67% (1/6) 1 entry
ENSG00000116062 MSH6 pharyngeal squamous cell carcinoma sequence_alteration 0.6944% (1/144) 1 entry
ENSG00000116062 MSH6 Gastrointestinal stromal tumor sequence_alteration 0.6757% (1/148) 1 entry
ENSG00000116062 MSH6 embryonal rhabdomyosarcoma missense_variant 1.163% (1/86) 1 entry
ENSG00000116062 MSH6 leiomyosarcoma missense_variant 2.0% (2/100) 1 entry
ENSG00000116062 MSH6 transitional cell carcinoma of kidney missense_variant 100.0% (1/1) 1 entry
ENSG00000116062 MSH6 renal carcinoma missense_variant 4.762% (1/21) 1 entry
ENSG00000116062 MSH6 B-cell neoplasm sequence_alteration 5.556% (1/18) 1 entry
ENSG00000116062 MSH6 benign blood vessel neoplasm missense_variant 25.0% (1/4) 1 entry
ENSG00000116062 MSH6 pharyngeal squamous cell carcinoma conservative_inframe_deletion 0.6944% (1/144) 1 entry
ENSG00000116062 MSH6 bladder transitional cell carcinoma stop_gained 2.603% (12/461) 1 entry
ENSG00000116062 MSH6 glioma frameshift_variant 1.488% (10/672) 1 entry
ENSG00000116062 MSH6 diffuse gastric adenocarcinoma frameshift_variant 1.46% (2/137) 1 entry
ENSG00000116062 MSH6 Pleural Epithelioid Mesothelioma sequence_alteration 0.5025% (1/199) 1 entry
ENSG00000116062 MSH6 urothelial carcinoma missense_variant 2.339% (4/171) 1 entry
ENSG00000116062 MSH6 Invasive Breast Carcinoma stop_gained 1.493% (1/67) 1 entry
ENSG00000116062 MSH6 bile duct adenocarcinoma missense_variant 0.4594% (3/653) 1 entry
ENSG00000116062 MSH6 ovarian clear cell adenocarcinoma missense_variant 2.778% (1/36) 1 entry
ENSG00000116062 MSH6 Mixed Lobular and Ductal Breast Carcinoma conservative_inframe_deletion 1.333% (1/75) 1 entry
ENSG00000116062 MSH6 urothelial carcinoma stop_gained 2.339% (4/171) 1 entry
ENSG00000116062 MSH6 chronic lymphocytic leukemia missense_variant 0.3367% (3/891) 1 entry
ENSG00000116062 MSH6 Mantle cell lymphoma sequence_alteration 1.724% (1/58) 1 entry
ENSG00000116062 MSH6 mucosal melanoma missense_variant 1.429% (1/70) 1 entry
ENSG00000116062 MSH6 colon carcinoma missense_variant 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 Gastrointestinal stromal tumor frameshift_variant 0.6757% (1/148) 1 entry
ENSG00000116062 MSH6 Breast Carcinoma by Gene Expression Profile missense_variant 1.064% (1/94) 1 entry
ENSG00000116062 MSH6 large cell lung carcinoma stop_gained 10.53% (2/19) 1 entry
ENSG00000116062 MSH6 ovarian serous adenocarcinoma stop_gained 0.5708% (5/876) 1 entry
ENSG00000116062 MSH6 adrenocortical adenoma sequence_alteration 2.439% (1/41) 1 entry
ENSG00000116062 MSH6 mucosal melanoma sequence_alteration 1.429% (1/70) 1 entry
ENSG00000116062 MSH6 Juvenile Xanthogranuloma sequence_alteration 5.882% (1/17) 1 entry
ENSG00000116062 MSH6 gastric carcinoma missense_variant 2.41% (2/83) 1 entry
ENSG00000116062 MSH6 non-small cell lung carcinoma stop_gained 2.174% (3/138) 1 entry
ENSG00000116062 MSH6 carcinoma conservative_inframe_deletion 50.0% (1/2) 1 entry
ENSG00000116062 MSH6 Appendix Goblet Cell Carcinoid stop_gained 12.5% (1/8) 1 entry
ENSG00000116062 MSH6 Mucinous Gastric Adenocarcinoma frameshift_variant 100.0% (1/1) 1 entry
ENSG00000116062 MSH6 papillary thyroid carcinoma sequence_alteration 0.4098% (2/488) 1 entry
ENSG00000116062 MSH6 Breast Carcinoma by Gene Expression Profile sequence_alteration 1.064% (1/94) 1 entry
ENSG00000116062 MSH6 acute lymphoblastic leukemia missense_variant 0.2985% (1/335) 1 entry
ENSG00000116062 MSH6 female breast carcinoma stop_gained 1.188% (5/421) 1 entry
ENSG00000116062 MSH6 leiomyosarcoma stop_gained 2.0% (2/100) 1 entry
ENSG00000116062 MSH6 clear cell renal carcinoma stop_gained 0.5569% (9/1616) 1 entry
ENSG00000116062 MSH6 ovarian clear cell adenocarcinoma stop_gained 2.778% (1/36) 1 entry
ENSG00000116062 MSH6 small cell lung carcinoma stop_gained 1.114% (5/449) 1 entry
ENSG00000116062 MSH6 anaplastic astrocytoma sequence_alteration 2.055% (3/146) 1 entry
ENSG00000116062 MSH6 transitional cell carcinoma of kidney sequence_alteration 100.0% (1/1) 1 entry
ENSG00000116062 MSH6 small cell lung carcinoma frameshift_variant 1.114% (5/449) 1 entry
ENSG00000116062 MSH6 nasopharyngeal squamous cell carcinoma stop_gained 1.623% (5/308) 1 entry
ENSG00000116062 MSH6 chromophobe renal cell carcinoma missense_variant 0.6757% (1/148) 1 entry
ENSG00000116062 MSH6 bile duct adenocarcinoma frameshift_variant 0.4594% (3/653) 1 entry
ENSG00000116062 MSH6 lung adenocarcinoma frameshift_variant 1.041% (29/2785) 1 entry
ENSG00000116062 MSH6 bile duct adenocarcinoma stop_gained 0.4594% (3/653) 1 entry
ENSG00000116062 MSH6 Hodgkins lymphoma missense_variant 1.695% (1/59) 1 entry
ENSG00000116062 MSH6 bile duct adenocarcinoma sequence_alteration 0.4594% (3/653) 1 entry
ENSG00000116062 MSH6 Mantle cell lymphoma missense_variant 1.724% (1/58) 1 entry
ENSG00000116062 MSH6 head and neck squamous cell carcinoma sequence_alteration 0.5109% (4/783) 1 entry
ENSG00000116062 MSH6 pharyngeal squamous cell carcinoma frameshift_variant 0.6944% (1/144) 1 entry
ENSG00000116062 MSH6 bladder transitional cell carcinoma frameshift_variant 2.603% (12/461) 1 entry
ENSG00000116062 MSH6 central nervous system primitive neuroectodermal neoplasm missense_variant 0.2232% (1/448) 1 entry
ENSG00000116062 MSH6 diffuse gastric adenocarcinoma sequence_alteration 1.46% (2/137) 1 entry
ENSG00000116062 MSH6 hairy cell leukemia sequence_alteration 4.167% (1/24) 1 entry
ENSG00000116062 MSH6 ovarian serous adenocarcinoma frameshift_variant 0.5708% (5/876) 1 entry
ENSG00000116062 MSH6 urothelial carcinoma frameshift_variant 2.339% (4/171) 1 entry
ENSG00000116062 MSH6 Endometrial Clear Cell Adenocarcinoma sequence_alteration 4.082% (4/98) 1 entry
ENSG00000116062 MSH6 ovarian clear cell adenocarcinoma sequence_alteration 2.778% (1/36) 1 entry
ENSG00000116062 MSH6 rectal adenocarcinoma stop_gained 2.222% (13/585) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116062 MSH6 MESO 0.0021 high
ENSG00000116062 MSH6 SARC 0.0065 high
ENSG00000116062 MSH6 PAAD 0.0014 high
ENSG00000116062 MSH6 UCEC 0.00033 high
ENSG00000116062 MSH6 LUSC 0.0037 low
ENSG00000116062 MSH6 HNSC 0.008 low
ENSG00000116062 MSH6 READ 0.023 low
ENSG00000116062 MSH6 KICH 0.00045 high
ENSG00000116062 MSH6 LUAD 0.019 high
ENSG00000116062 MSH6 PCPG 0.029 high
ENSG00000116062 MSH6 UCS 0.004 low
ENSG00000116062 MSH6 DLBC 0.025 low
ENSG00000116062 MSH6 KIRC 0.044 low
ENSG00000116062 MSH6 PRAD 0.025 high
ENSG00000116062 MSH6 BLCA 0.023 high
ENSG00000116062 MSH6 CESC 0.006 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116062 MSH6 LUSC Amp 3.075342 0.263715 0.563202 0.524950
ENSG00000116062 MSH6 TGCT Amp 1.008111 0.131892 0.426757 0.386667