Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000115211 Gene ID 8890 Accession 3260
Symbol EIF2B4 Alias VWM4;EIF2B;EIF-2B;EIF2Bdelta Full Name eukaryotic translation initiation factor 2B subunit delta
Status Confidence Length 5987 bases Strand Minus strand
Position 2 : 27364352 - 27370338 RNA binding domain IF-2B
Summary Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000394397 IF-2B PF01008 6.6e-90 1
ENSP00000233552 IF-2B PF01008 6.6e-90 1
ENSP00000394869 IF-2B PF01008 7.3e-90 1
ENSP00000429323 IF-2B PF01008 7.4e-90 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
EIF2B4-201 ENST00000347454 1644 523aa ENSP00000233552
EIF2B4-209 ENST00000478311 607 No protein -
EIF2B4-202 ENST00000405940 1570 235aa ENSP00000384375
EIF2B4-205 ENST00000445933 1608 522aa ENSP00000394397
EIF2B4-206 ENST00000451130 1633 543aa ENSP00000394869
EIF2B4-210 ENST00000493344 1949 544aa ENSP00000429323
EIF2B4-208 ENST00000475582 4293 No protein -
EIF2B4-203 ENST00000417567 761 No protein -
EIF2B4-204 ENST00000418146 742 12aa ENSP00000407956
EIF2B4-207 ENST00000462749 1089 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
60446Insulin-Like Growth Factor I1.5840000E-00627329260
77498Immunoglobulins4E-623382691

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000115211homo_sapiensENSP0000004066339.024419.2412homo_sapiensENSP0000023355227.533513.5755
ENSG00000115211homo_sapiensENSP0000041625048.524626.8852homo_sapiensENSP0000023355228.298315.6788
ENSG00000115211homo_sapiensENSP0000026612647.293426.2108homo_sapiensENSP0000023355231.7417.5908

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000115211homo_sapiensENSP0000023355292.160691.587nomascus_leucogenysENSNLEP0000003962992.514491.9386
ENSG00000115211homo_sapiensENSP0000023355299.617699.6176pan_paniscusENSPPAP0000000758299.617699.6176
ENSG00000115211homo_sapiensENSP0000023355299.617699.4264pongo_abeliiENSPPYP0000001401799.617699.4264
ENSG00000115211homo_sapiensENSP0000023355299.617699.4264pan_troglodytesENSPTRP0000002021199.617699.4264
ENSG00000115211homo_sapiensENSP0000023355299.808899.8088gorilla_gorillaENSGGOP0000001070599.808899.8088
ENSG00000115211homo_sapiensENSP0000023355282.791677.8203ornithorhynchus_anatinusENSOANP0000002742081.238376.3602
ENSG00000115211homo_sapiensENSP0000023355287.189379.3499sarcophilus_harrisiiENSSHAP0000001589083.669776.1468
ENSG00000115211homo_sapiensENSP0000023355284.321277.8203notamacropus_eugeniiENSMEUP0000000136288.376881.5631
ENSG00000115211homo_sapiensENSP0000023355293.49990.4398dasypus_novemcinctusENSDNOP0000001380993.49990.4398
ENSG00000115211homo_sapiensENSP0000023355264.818461.7591erinaceus_europaeusENSEEUP0000000322865.192362.1154
ENSG00000115211homo_sapiensENSP0000023355292.734289.2925echinops_telfairiENSETEP0000000249192.734289.2925
ENSG00000115211homo_sapiensENSP0000023355297.323197.1319callithrix_jacchusENSCJAP0000004756096.768196.5779
ENSG00000115211homo_sapiensENSP0000023355297.323196.5583cercocebus_atysENSCATP0000000170493.738593.0018
ENSG00000115211homo_sapiensENSP0000023355297.514396.7495macaca_fascicularisENSMFAP0000002580293.7593.0147
ENSG00000115211homo_sapiensENSP0000023355299.04498.6616macaca_mulattaENSMMUP0000004223899.04498.6616
ENSG00000115211homo_sapiensENSP0000023355296.175995.4111macaca_nemestrinaENSMNEP0000002872887.17586.4818
ENSG00000115211homo_sapiensENSP0000023355297.514396.7495papio_anubisENSPANP0000000784693.7593.0147
ENSG00000115211homo_sapiensENSP0000023355297.131996.3671mandrillus_leucophaeusENSMLEP0000000135693.554392.8177
ENSG00000115211homo_sapiensENSP0000023355295.411191.9694tursiops_truncatusENSTTRP0000001187795.22991.7939
ENSG00000115211homo_sapiensENSP0000023355293.116690.4398vulpes_vulpesENSVVUP0000002248189.194186.63
ENSG00000115211homo_sapiensENSP0000023355290.822285.8509mus_spretusMGP_SPRETEiJ_P006994183.922379.3286
ENSG00000115211homo_sapiensENSP0000023355294.072791.0134equus_asinusENSEASP0000501326890.275287.3394
ENSG00000115211homo_sapiensENSP0000023355292.160689.1013capra_hircusENSCHIP0000003068789.424986.4564
ENSG00000115211homo_sapiensENSP0000023355293.307890.631loxodonta_africanaENSLAFP0000000469293.129890.458
ENSG00000115211homo_sapiensENSP0000023355291.778289.2925panthera_leoENSPLOP0000000531488.073485.6881
ENSG00000115211homo_sapiensENSP0000023355291.778289.1013ailuropoda_melanoleucaENSAMEP0000000164188.073485.5046
ENSG00000115211homo_sapiensENSP0000023355293.690290.2486bos_indicus_hybridENSBIXP0000504546789.908386.6055
ENSG00000115211homo_sapiensENSP0000023355287.954183.5564oryctolagus_cuniculusENSOCUP0000002210288.122683.7165
ENSG00000115211homo_sapiensENSP0000023355295.028792.3518equus_caballusENSECAP0000007260094.128891.4773
ENSG00000115211homo_sapiensENSP0000023355292.734290.2486canis_lupus_familiarisENSCAFP0084501024388.990886.6055
ENSG00000115211homo_sapiensENSP0000023355293.307891.2046panthera_pardusENSPPRP0000000519893.129891.0305
ENSG00000115211homo_sapiensENSP0000023355295.411192.7342marmota_marmota_marmotaENSMMMP0000002346495.047692.381
ENSG00000115211homo_sapiensENSP0000023355294.072790.0574balaenoptera_musculusENSBMSP0001001421690.275286.422
ENSG00000115211homo_sapiensENSP0000023355292.160687.7629cavia_porcellusENSCPOP0000003028188.440484.2202
ENSG00000115211homo_sapiensENSP0000023355291.969489.1013felis_catusENSFCAP0000004552888.256985.5046
ENSG00000115211homo_sapiensENSP0000023355293.307890.8222ursus_americanusENSUAMP0000000830893.129890.6489
ENSG00000115211homo_sapiensENSP0000023355285.08678.0115monodelphis_domesticaENSMODP0000001955688.118880.7921
ENSG00000115211homo_sapiensENSP0000023355293.881590.4398bison_bison_bisonENSBBBP0000000763090.091786.789
ENSG00000115211homo_sapiensENSP0000023355294.455191.0134monodon_monocerosENSMMNP0001500836890.642287.3394
ENSG00000115211homo_sapiensENSP0000023355294.072790.2486sus_scrofaENSSSCP0000004467290.607786.9245
ENSG00000115211homo_sapiensENSP0000023355295.028792.3518microcebus_murinusENSMICP0000001790891.192788.6239
ENSG00000115211homo_sapiensENSP0000023355237.858536.3289octodon_degusENSODEP0000001261388.789285.2018
ENSG00000115211homo_sapiensENSP0000023355279.732375.5258octodon_degusENSODEP0000001724292.873187.9733
ENSG00000115211homo_sapiensENSP0000023355291.778288.1453jaculus_jaculusENSJJAP0000001347382.474279.2096
ENSG00000115211homo_sapiensENSP0000023355294.455191.0134ovis_aries_rambouilletENSOARP0002000259790.642287.3394
ENSG00000115211homo_sapiensENSP0000023355293.307890.8222ursus_maritimusENSUMAP0000002799593.129890.6489
ENSG00000115211homo_sapiensENSP0000023355284.321279.1587ochotona_princepsENSOPRP0000000986084.644979.4626
ENSG00000115211homo_sapiensENSP0000023355294.455191.0134delphinapterus_leucasENSDLEP0000002963079.806176.8982
ENSG00000115211homo_sapiensENSP0000023355294.455190.8222physeter_catodonENSPCTP0000501000590.642287.156
ENSG00000115211homo_sapiensENSP0000023355290.248685.2772mus_caroliMGP_CAROLIEiJ_P006731283.392278.7986
ENSG00000115211homo_sapiensENSP0000023355290.822285.8509mus_musculusENSMUSP0000014436183.922379.3286
ENSG00000115211homo_sapiensENSP0000023355292.734290.0574dipodomys_ordiiENSDORP0000000635087.230284.7122
ENSG00000115211homo_sapiensENSP0000023355293.690291.3958mustela_putorius_furoENSMPUP0000000968193.690291.3958
ENSG00000115211homo_sapiensENSP0000023355296.367195.6023aotus_nancymaaeENSANAP0000002417392.138991.4077
ENSG00000115211homo_sapiensENSP0000023355295.793595.0287saimiri_boliviensis_boliviensisENSSBOP0000002820290.596789.8734
ENSG00000115211homo_sapiensENSP0000023355298.852898.6616chlorocebus_sabaeusENSCSAP0000000607598.852898.6616
ENSG00000115211homo_sapiensENSP0000023355258.508655.8317tupaia_belangeriENSTBEP0000001120093.57889.2966
ENSG00000115211homo_sapiensENSP0000023355292.351888.5277mesocricetus_auratusENSMAUP0000000927688.623984.9541
ENSG00000115211homo_sapiensENSP0000023355295.219991.9694phocoena_sinusENSPSNP0000000725895.038291.7939
ENSG00000115211homo_sapiensENSP0000023355295.028792.3518camelus_dromedariusENSCDRP0000501223789.068186.5591
ENSG00000115211homo_sapiensENSP0000023355282.982878.5851carlito_syrichtaENSTSYP0000001929088.752684.0491
ENSG00000115211homo_sapiensENSP0000023355291.395888.7189panthera_tigris_altaicaENSPTIP0000000783987.706485.1376
ENSG00000115211homo_sapiensENSP0000023355291.013485.6597rattus_norvegicusENSRNOP0000009295884.098979.1519
ENSG00000115211homo_sapiensENSP0000023355294.646391.9694prolemur_simusENSPSMP0000000352090.825788.2569
ENSG00000115211homo_sapiensENSP0000023355290.248686.8069microtus_ochrogasterENSMOCP0000001340785.04581.8018
ENSG00000115211homo_sapiensENSP0000023355287.954182.9828sorex_araneusENSSARP0000000602289.494284.4358
ENSG00000115211homo_sapiensENSP0000023355291.204686.2333peromyscus_maniculatus_bairdiiENSPEMP0000001250384.275679.682
ENSG00000115211homo_sapiensENSP0000023355293.881590.4398bos_mutusENSBMUP0000001160190.091786.789
ENSG00000115211homo_sapiensENSP0000023355290.822285.8509mus_spicilegusENSMSIP0000001839483.922379.3286
ENSG00000115211homo_sapiensENSP0000023355292.160688.5277cricetulus_griseus_chok1gshdENSCGRP0000101579888.440484.9541
ENSG00000115211homo_sapiensENSP0000023355294.837592.9254pteropus_vampyrusENSPVAP0000001430694.656592.7481
ENSG00000115211homo_sapiensENSP0000023355292.734289.1013myotis_lucifugusENSMLUP0000000125292.734289.1013
ENSG00000115211homo_sapiensENSP0000023355287.762980.1147vombatus_ursinusENSVURP0001002692384.220276.8807
ENSG00000115211homo_sapiensENSP0000023355294.837592.3518rhinolophus_ferrumequinumENSRFEP0001001838994.656592.1756
ENSG00000115211homo_sapiensENSP0000023355293.881591.7782neovison_visonENSNVIP0000002129193.881591.7782
ENSG00000115211homo_sapiensENSP0000023355289.674986.2333bos_taurusENSBTAP0000002599188.657885.2552
ENSG00000115211homo_sapiensENSP0000023355292.925488.7189heterocephalus_glaber_femaleENSHGLP0000001305889.174385.1376
ENSG00000115211homo_sapiensENSP0000023355297.705596.9407rhinopithecus_bietiENSRBIP0000003164093.933893.1985
ENSG00000115211homo_sapiensENSP0000023355294.455192.3518canis_lupus_dingoENSCAFP0002003109194.095292
ENSG00000115211homo_sapiensENSP0000023355295.219992.3518sciurus_vulgarisENSSVLP0000503296294.857192
ENSG00000115211homo_sapiensENSP0000023355287.762980.3059phascolarctos_cinereusENSPCIP0000001751483.759176.6423
ENSG00000115211homo_sapiensENSP0000023355293.307891.0134procavia_capensisENSPCAP0000000068993.307891.0134
ENSG00000115211homo_sapiensENSP0000023355292.160688.1453nannospalax_galiliENSNGAP0000000584383.103479.4828
ENSG00000115211homo_sapiensENSP0000023355293.881590.4398bos_grunniensENSBGRP0000001537490.091786.789
ENSG00000115211homo_sapiensENSP0000023355290.822287.5717chinchilla_lanigeraENSCLAP0000000982985.740182.6715
ENSG00000115211homo_sapiensENSP0000023355294.072790.4398cervus_hanglu_yarkandensisENSCHYP0000001046790.275286.789
ENSG00000115211homo_sapiensENSP0000023355294.263990.8222catagonus_wagneriENSCWAP0000001842890.458787.156
ENSG00000115211homo_sapiensENSP0000023355293.881590.8222ictidomys_tridecemlineatusENSSTOP0000001020388.949386.0507
ENSG00000115211homo_sapiensENSP0000023355295.602392.9254otolemur_garnettiiENSOGAP0000001104994.876792.2201
ENSG00000115211homo_sapiensENSP0000023355296.749596.1759cebus_imitatorENSCCAP0000002464396.564995.9924
ENSG00000115211homo_sapiensENSP0000023355293.49990.2486urocitellus_parryiiENSUPAP0001000774589.724886.6055
ENSG00000115211homo_sapiensENSP0000023355294.455190.4398moschus_moschiferusENSMMSP0000000973078.412775.0794
ENSG00000115211homo_sapiensENSP0000023355299.04498.6616rhinopithecus_roxellanaENSRROP0000004129399.04498.6616
ENSG00000115211homo_sapiensENSP0000023355228.298326.7686mus_pahariMGP_PahariEiJ_P008172591.35886.4198
ENSG00000115211homo_sapiensENSP0000023355295.793593.6902propithecus_coquereliENSPCOP0000001791095.610793.5115
ENSG00000115211homo_sapiensENSP0000023355238.623321.7973caenorhabditis_elegansF11A3.2a.138.185321.5501
ENSG00000115211homo_sapiensENSP0000023355260.038240.9178drosophila_melanogasterFBpp007192350.159734.1853
ENSG00000115211homo_sapiensENSP0000023355261.759144.1683ciona_intestinalisENSCINP0000000723067.012547.9253
ENSG00000115211homo_sapiensENSP0000023355257.743846.8451petromyzon_marinusENSPMAP0000000953677.435962.8205
ENSG00000115211homo_sapiensENSP0000023355268.068853.3461eptatretus_burgeriENSEBUP0000001406066.542152.1495
ENSG00000115211homo_sapiensENSP0000023355274.378660.2294callorhinchus_miliiENSCMIP0000003852472.846458.9888
ENSG00000115211homo_sapiensENSP0000023355262.715150.0956latimeria_chalumnaeENSLACP0000000055461.538549.1557
ENSG00000115211homo_sapiensENSP0000023355276.67363.0975lepisosteus_oculatusENSLOCP0000002067774.12260.9981
ENSG00000115211homo_sapiensENSP0000023355275.143462.7151clupea_harengusENSCHAP0000002531570.053558.467
ENSG00000115211homo_sapiensENSP0000023355275.143461.7591danio_rerioENSDARP0000010670772.777859.8148
ENSG00000115211homo_sapiensENSP0000023355273.996261.1855carassius_auratusENSCARP0000005981971.139758.8235
ENSG00000115211homo_sapiensENSP0000023355274.76161.3767carassius_auratusENSCARP0000005416072.140259.2251
ENSG00000115211homo_sapiensENSP0000023355274.952262.1415carassius_auratusENSCARP0000004851171.272759.0909
ENSG00000115211homo_sapiensENSP0000023355271.128158.3174carassius_auratusENSCARP0000012327870.722457.9848
ENSG00000115211homo_sapiensENSP0000023355273.996261.5679astyanax_mexicanusENSAMXP000000198597562.4031
ENSG00000115211homo_sapiensENSP0000023355275.143462.5239ictalurus_punctatusENSIPUP0000002456673.872261.4662
ENSG00000115211homo_sapiensENSP0000023355276.864262.5239esox_luciusENSELUP0000007741572.958359.3466
ENSG00000115211homo_sapiensENSP0000023355274.952261.9503electrophorus_electricusENSEEEP0000005100772.191559.6685
ENSG00000115211homo_sapiensENSP0000023355275.525862.9063oncorhynchus_kisutchENSOKIP0000509559972.477160.367
ENSG00000115211homo_sapiensENSP0000023355274.378660.6119oncorhynchus_kisutchENSOKIP0000502088573.120359.5865
ENSG00000115211homo_sapiensENSP0000023355272.657758.6998oncorhynchus_mykissENSOMYP0000011172771.02857.3832
ENSG00000115211homo_sapiensENSP0000023355275.143462.9063oncorhynchus_mykissENSOMYP0000006636573.320961.3806
ENSG00000115211homo_sapiensENSP0000023355275.525863.0975salmo_salarENSSSAP0000005192373.831861.6822
ENSG00000115211homo_sapiensENSP0000023355274.76161.3767salmo_salarENSSSAP0000002986472.007459.116
ENSG00000115211homo_sapiensENSP0000023355274.378661.3767salmo_truttaENSSTUP0000000533473.120360.3383
ENSG00000115211homo_sapiensENSP0000023355274.378660.9943salmo_truttaENSSTUP0000006865169.588657.0662
ENSG00000115211homo_sapiensENSP0000023355274.76162.1415gadus_morhuaENSGMOP0000004670770.961958.9837
ENSG00000115211homo_sapiensENSP0000023355275.908262.5239fundulus_heteroclitusENSFHEP0000001777472.445359.6715
ENSG00000115211homo_sapiensENSP0000023355276.864262.9063poecilia_reticulataENSPREP0000002843973.22459.9271
ENSG00000115211homo_sapiensENSP0000023355275.334662.3327xiphophorus_maculatusENSXMAP0000002760872.426559.9265
ENSG00000115211homo_sapiensENSP0000023355275.71762.5239oryzias_latipesENSORLP0000002038074.436161.4662
ENSG00000115211homo_sapiensENSP0000023355274.952260.9943cyclopterus_lumpusENSCLMP0000504063773.134359.5149
ENSG00000115211homo_sapiensENSP0000023355275.908261.9503oreochromis_niloticusENSONIP0000003691771.402958.2734
ENSG00000115211homo_sapiensENSP0000023355275.908261.3767haplochromis_burtoniENSHBUP0000001105172.445358.5766
ENSG00000115211homo_sapiensENSP0000023355275.71761.3767astatotilapia_callipteraENSACLP0000001783872.262858.5766
ENSG00000115211homo_sapiensENSP0000023355275.525861.5679sparus_aurataENSSAUP0001002200371.94958.6521
ENSG00000115211homo_sapiensENSP0000023355275.334661.1855lates_calcariferENSLCAP0001003260573.782859.9251
ENSG00000115211homo_sapiensENSP0000023355274.187462.7151xenopus_tropicalisENSXETP0000011924471.062360.0733
ENSG00000115211homo_sapiensENSP0000023355266.539256.4054chrysemys_picta_belliiENSCPBP0000002641481.308468.9252
ENSG00000115211homo_sapiensENSP0000023355220.841316.0612sphenodon_punctatusENSSPUP0000000070658.602145.1613
ENSG00000115211homo_sapiensENSP0000023355268.833659.4646crocodylus_porosusENSCPRP0000500585883.526772.1578
ENSG00000115211homo_sapiensENSP0000023355252.963745.5067laticauda_laticaudataENSLLTP0000002309174.462463.9785
ENSG00000115211homo_sapiensENSP0000023355275.334665.2008notechis_scutatusENSNSUP0000000707276.356666.0853
ENSG00000115211homo_sapiensENSP0000023355274.952264.6272pseudonaja_textilisENSPTXP0000001476978.714967.8715
ENSG00000115211homo_sapiensENSP0000023355275.525863.6711anas_platyrhynchos_platyrhynchosENSAPLP0000002435575.961564.0385
ENSG00000115211homo_sapiensENSP0000023355275.71764.6272gallus_gallusENSGALP0001001230553.01245.2477
ENSG00000115211homo_sapiensENSP0000023355269.980959.6558meleagris_gallopavoENSMGAP0000002016973.939463.0303
ENSG00000115211homo_sapiensENSP0000023355273.422660.9943serinus_canariaENSSCAP0000001837559.442749.3808
ENSG00000115211homo_sapiensENSP0000023355274.569863.4799parus_majorENSPMJP0000000936974.712663.6015
ENSG00000115211homo_sapiensENSP0000023355264.818455.4493anolis_carolinensisENSACAP0000002599875.501164.588
ENSG00000115211homo_sapiensENSP0000023355274.378660.6119neolamprologus_brichardiENSNBRP0000002544074.807760.9615
ENSG00000115211homo_sapiensENSP0000023355275.908265.5832naja_najaENSNNAP0000000393668.804259.4454
ENSG00000115211homo_sapiensENSP0000023355265.965655.4493podarcis_muralisENSPMRP000000074547563.0435
ENSG00000115211homo_sapiensENSP0000023355270.745759.847geospiza_fortisENSGFOP0000000519575.975464.271
ENSG00000115211homo_sapiensENSP0000023355274.952263.6711taeniopygia_guttataENSTGUP0000001520853.846245.7418
ENSG00000115211homo_sapiensENSP0000023355277.629162.1415erpetoichthys_calabaricusENSECRP0000000483374.632459.7426
ENSG00000115211homo_sapiensENSP0000023355275.143461.7591kryptolebias_marmoratusENSKMAP0000001787671.97859.1575
ENSG00000115211homo_sapiensENSP0000023355275.525865.7744salvator_merianaeENSSMRP0000001721574.387964.7834
ENSG00000115211homo_sapiensENSP0000023355275.143462.3327oryzias_javanicusENSOJAP0000003811472.777860.3704
ENSG00000115211homo_sapiensENSP0000023355273.613861.1855amphilophus_citrinellusENSACIP0000000453172.504760.2637
ENSG00000115211homo_sapiensENSP0000023355275.143462.5239dicentrarchus_labraxENSDLAP0000507386570.430158.6021
ENSG00000115211homo_sapiensENSP0000023355274.952262.7151amphiprion_perculaENSAPEP0000000309571.532859.854
ENSG00000115211homo_sapiensENSP0000023355274.569862.1415oryzias_sinensisENSOSIP0000002543673.308361.0902
ENSG00000115211homo_sapiensENSP0000023355268.833657.3614pelodiscus_sinensisENSPSIP0000000447572.727360.6061
ENSG00000115211homo_sapiensENSP0000023355273.613861.1855gopherus_evgoodeiENSGEVP0000500780273.613861.1855
ENSG00000115211homo_sapiensENSP0000023355274.378662.3327chelonoidis_abingdoniiENSCABP0000002050478.427465.7258
ENSG00000115211homo_sapiensENSP0000023355276.290662.7151seriola_dumeriliENSSDUP0000001986574.859361.5385
ENSG00000115211homo_sapiensENSP0000023355275.334660.9943cottoperca_gobioENSCGOP0000003023874.339660.1887
ENSG00000115211homo_sapiensENSP0000023355274.378662.3327struthio_camelus_australisENSSCUP0000000196976.125263.7965
ENSG00000115211homo_sapiensENSP0000023355274.569863.2887anser_brachyrhynchusENSABRP000000089937866.2
ENSG00000115211homo_sapiensENSP0000023355274.378661.9503gasterosteus_aculeatusENSGACP0000001414571.771259.7786
ENSG00000115211homo_sapiensENSP0000023355275.71762.9063cynoglossus_semilaevisENSCSEP0000002154674.157361.6105
ENSG00000115211homo_sapiensENSP0000023355275.334662.1415poecilia_formosaENSPFOP0000000920673.644960.7477
ENSG00000115211homo_sapiensENSP0000023355277.055563.0975myripristis_murdjanENSMMDP0000505365171.075858.2011
ENSG00000115211homo_sapiensENSP0000023355274.378660.9943sander_luciopercaENSSLUP0000000844671.63958.7477
ENSG00000115211homo_sapiensENSP0000023355276.099464.4359strigops_habroptilaENSSHBP0000502109076.099464.4359
ENSG00000115211homo_sapiensENSP0000023355275.908263.0975amphiprion_ocellarisENSAOCP0000001885072.445360.219
ENSG00000115211homo_sapiensENSP0000023355247.992436.9025terrapene_carolina_triunguisENSTMTP0000001345863.867749.1094
ENSG00000115211homo_sapiensENSP0000023355221.414916.4436terrapene_carolina_triunguisENSTMTP0000001356168.292752.439
ENSG00000115211homo_sapiensENSP0000023355273.996261.7591hucho_huchoENSHHUP0000001352967.071155.9792
ENSG00000115211homo_sapiensENSP0000023355274.378660.8031betta_splendensENSBSLP0000001117468.485955.9859
ENSG00000115211homo_sapiensENSP0000023355275.908262.9063pygocentrus_nattereriENSPNAP0000003648872.710660.2564
ENSG00000115211homo_sapiensENSP0000023355274.76161.3767anabas_testudineusENSATEP0000004375971.480858.6837
ENSG00000115211homo_sapiensENSP0000023355261.376745.1243ciona_savignyiENSCSAVP0000001245268.589750.4273
ENSG00000115211homo_sapiensENSP0000023355248.183631.74saccharomyces_cerevisiaeYGR083C38.709725.4992
ENSG00000115211homo_sapiensENSP0000023355276.290662.7151seriola_lalandi_dorsalisENSSLDP0000001692074.859361.5385
ENSG00000115211homo_sapiensENSP0000023355274.187461.5679labrus_bergyltaENSLBEP0000000222172.523460.1869
ENSG00000115211homo_sapiensENSP0000023355275.71761.1855pundamilia_nyerereiENSPNYP0000000951772.262858.3942
ENSG00000115211homo_sapiensENSP0000023355276.099462.3327mastacembelus_armatusENSMAMP0000002551072.627759.4891
ENSG00000115211homo_sapiensENSP0000023355275.908262.7151stegastes_partitusENSSPAP0000001723572.445359.854
ENSG00000115211homo_sapiensENSP0000023355275.334662.9063acanthochromis_polyacanthusENSAPOP0000003210471.636459.8182
ENSG00000115211homo_sapiensENSP0000023355275.334664.2447aquila_chrysaetos_chrysaetosENSACCP0002002006975.047664
ENSG00000115211homo_sapiensENSP0000023355275.143461.5679nothobranchius_furzeriENSNFUP0001500129066.950654.8552
ENSG00000115211homo_sapiensENSP0000023355273.996262.5239cyprinodon_variegatusENSCVAP0000003282972.471961.236
ENSG00000115211homo_sapiensENSP0000023355275.143462.3327denticeps_clupeoidesENSDCDP0000006322073.320960.8209
ENSG00000115211homo_sapiensENSP0000023355275.143462.1415larimichthys_croceaENSLCRP0000503387168.229256.4236
ENSG00000115211homo_sapiensENSP0000023355274.76162.1415takifugu_rubripesENSTRUP0000001894166.271255.0847
ENSG00000115211homo_sapiensENSP0000023355269.407359.0822ficedula_albicollisENSFALP0000001168777.564166.0256
ENSG00000115211homo_sapiensENSP0000023355273.996260.0382hippocampus_comesENSHCOP0000000512473.714359.8095
ENSG00000115211homo_sapiensENSP0000023355274.76161.7591cyprinus_carpio_carpioENSCCRP0000013222369.69757.5758
ENSG00000115211homo_sapiensENSP0000023355275.143461.5679cyprinus_carpio_carpioENSCCRP0000005319171.584758.6521
ENSG00000115211homo_sapiensENSP0000023355274.952264.0535coturnix_japonicaENSCJPP0000501431779.191967.6768
ENSG00000115211homo_sapiensENSP0000023355275.334662.1415poecilia_latipinnaENSPLAP0000002968873.644960.7477
ENSG00000115211homo_sapiensENSP0000023355275.143462.1415sinocyclocheilus_grahamiENSSGRP0000005714773.184460.5214
ENSG00000115211homo_sapiensENSP0000023355274.952261.7591sinocyclocheilus_grahamiENSSGRP0000004412872.862560.0372
ENSG00000115211homo_sapiensENSP0000023355275.71761.3767maylandia_zebraENSMZEP0000502140572.262858.5766
ENSG00000115211homo_sapiensENSP0000023355269.598558.891tetraodon_nigroviridisENSTNIP0000001943876.955665.1163
ENSG00000115211homo_sapiensENSP0000023355277.629163.6711paramormyrops_kingsleyaeENSPKIP0000001993175.605262.0112
ENSG00000115211homo_sapiensENSP0000023355276.67363.0975scleropages_formosusENSSFOP0001503033663.349152.1327
ENSG00000115211homo_sapiensENSP0000023355274.76163.4799leptobrachium_leishanenseENSLLEP0000000884169.081358.6572
ENSG00000115211homo_sapiensENSP0000023355274.569861.7591scophthalmus_maximusENSSMAP0000001914371.038358.8342
ENSG00000115211homo_sapiensENSP0000023355275.908263.4799oryzias_melastigmaENSOMEP0000001416174.624162.406

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001541involved_in ovarian follicle development1IMPHomo_sapiens(9606)Process
GO:0003743contributes_to translation initiation factor activity1IDAHomo_sapiens(9606)Function
GO:0005085contributes_to guanyl-nucleotide exchange factor activity2IDA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005851part_of eukaryotic translation initiation factor 2B complex1IDAHomo_sapiens(9606)Component
GO:0006413involved_in translational initiation1IDAHomo_sapiens(9606)Process
GO:0006417involved_in regulation of translation1NASHomo_sapiens(9606)Process
GO:0009408involved_in response to heat2ISS,TASHomo_sapiens(9606)Process
GO:0009749involved_in response to glucose1ISSHomo_sapiens(9606)Process
GO:0014003involved_in oligodendrocyte development1IMPHomo_sapiens(9606)Process
GO:0031369enables translation initiation factor binding1ISSHomo_sapiens(9606)Function
GO:0042552involved_in myelination1IMPHomo_sapiens(9606)Process
GO:0043434involved_in response to peptide hormone1ISSHomo_sapiens(9606)Process
GO:0050852involved_in T cell receptor signaling pathway1IDAHomo_sapiens(9606)Process

Expression