Ensembl ID ENSG00000115211 Gene ID 8890 Accession 3260
Gene Symbol EIF2B4 Alias VWM4;EIF2B;EIF-2B;EIF2Bdelta Full Name eukaryotic translation initiation factor 2B subunit delta
Position 2 : 27364352 - 27370338 Length 5987 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000115211 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000115211 EIF2B4 0.28 1.25e-11 BRCA
ENSG00000115211 EIF2B4 0.50 1.65e-19 LUSC
ENSG00000115211 EIF2B4 0.52 1.80e-17 PRAD
ENSG00000115211 EIF2B4 0.60 2.52e-11 UCEC
ENSG00000115211 EIF2B4 0.47 2.07e-17 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000115211 EIF2B4 CHOL 0.013 high
ENSG00000115211 EIF2B4 UVM 0.013 high
ENSG00000115211 EIF2B4 LUSC 0.031 low
ENSG00000115211 EIF2B4 READ 0.0011 low
ENSG00000115211 EIF2B4 KIRP 0.022 high
ENSG00000115211 EIF2B4 THYM 0.036 low
ENSG00000115211 EIF2B4 BRCA 0.00046 low
ENSG00000115211 EIF2B4 COAD 0.036 high
ENSG00000115211 EIF2B4 OV 0.0044 low
ENSG00000115211 EIF2B4 BLCA 0.019 high
ENSG00000115211 EIF2B4 SKCM 0.0099 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000115211 EIF2B4 TGCT Amp 1.969747 0.177402 0.450564 0.406667
ENSG00000115211 EIF2B4 UCEC Amp 1.630686 0.125296 0.597638 0.228200