Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions Transmemebrane
Localizations Stress granucle
BulkPerturb-seq DataSet_01_136 DataSet_01_180

Description

Ensembl ID ENSG00000114416 Gene ID 8087 Accession 4023
Symbol FXR1 Alias FXR1P;CMYP9A;CMYP9B;MYOPMIL;MYORIBF Full Name FMR1 autosomal homolog 1
Status Confidence Length 114613 bases Strand Plus strand
Position 3 : 180868141 - 180982753 RNA binding domain Agenet , FXR_C1 , KH_1 , KH_9 , FXMRP1_C_core
Summary The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000388828 Agenet PF05641 2.3e-14 1
ENSP00000388828 Agenet PF05641 2.3e-14 2
ENSP00000388828 KH_9 PF17904 3.5e-36 3
ENSP00000388828 KH_1 PF00013 3.8e-16 4
ENSP00000388828 KH_1 PF00013 3.8e-16 5
ENSP00000388828 FXMRP1_C_core PF12235 2e-33 6
ENSP00000388828 FXMRP1_C_core PF12235 2e-33 7
ENSP00000388828 FXR_C1 PF16096 1.2e-38 8
ENSP00000513936 Agenet PF05641 2.7e-14 1
ENSP00000513936 Agenet PF05641 2.7e-14 2
ENSP00000513936 KH_9 PF17904 3.9e-36 3
ENSP00000513936 KH_1 PF00013 4.4e-16 4
ENSP00000513936 KH_1 PF00013 4.4e-16 5
ENSP00000513936 FXMRP1_C_core PF12235 9e-54 6
ENSP00000513936 FXR_C1 PF16096 1.3e-38 7
ENSP00000350170 Agenet PF05641 3.6e-14 1
ENSP00000350170 Agenet PF05641 3.6e-14 2
ENSP00000350170 KH_9 PF17904 3.6e-36 3
ENSP00000350170 KH_1 PF00013 5e-16 4
ENSP00000350170 FXMRP1_C_core PF12235 3.8e-33 5
ENSP00000350170 FXMRP1_C_core PF12235 3.8e-33 6
ENSP00000350170 FXR_C1 PF16096 1.3e-38 7
ENSP00000513937 Agenet PF05641 4.1e-14 1
ENSP00000513937 KH_9 PF17904 3.9e-36 2
ENSP00000513937 KH_1 PF00013 5.7e-16 3
ENSP00000513937 FXMRP1_C_core PF12235 1.1e-53 4
ENSP00000513937 FXR_C1 PF16096 1.4e-38 5
ENSP00000417513 Agenet PF05641 2.4e-12 1
ENSP00000417513 KH_9 PF17904 1.7e-06 2
ENSP00000418097 Agenet PF05641 3.3e-10 1
ENSP00000418097 KH_9 PF17904 3.5e-36 2
ENSP00000418097 KH_1 PF00013 4.9e-16 3
ENSP00000418097 KH_1 PF00013 4.9e-16 4
ENSP00000418097 FXMRP1_C_core PF12235 4.2e-33 5
ENSP00000418097 FXMRP1_C_core PF12235 4.2e-33 6
ENSP00000418097 FXR_C1 PF16096 1.3e-38 7
ENSP00000420643 Agenet PF05641 1.8e-05 1
ENSP00000420643 KH_9 PF17904 3.1e-36 2
ENSP00000420643 KH_1 PF00013 3.1e-16 3
ENSP00000420643 KH_1 PF00013 3.1e-16 4
ENSP00000420643 FXMRP1_C_core PF12235 1.5e-33 5
ENSP00000420643 FXMRP1_C_core PF12235 1.5e-33 6
ENSP00000420643 FXR_C1 PF16096 1.1e-38 7
ENSP00000419933 KH_9 PF17904 2.5e-37 1
ENSP00000420515 KH_9 PF17904 2.8e-36 1
ENSP00000420515 KH_1 PF00013 2.6e-16 2
ENSP00000420515 KH_1 PF00013 2.6e-16 3
ENSP00000420515 FXMRP1_C_core PF12235 1.2e-33 4
ENSP00000420515 FXMRP1_C_core PF12235 1.2e-33 5
ENSP00000420515 FXR_C1 PF16096 9.5e-39 6
ENSP00000307633 KH_9 PF17904 2.9e-36 1
ENSP00000307633 KH_1 PF00013 3.6e-16 2
ENSP00000307633 KH_1 PF00013 3.6e-16 3
ENSP00000307633 FXMRP1_C_core PF12235 3e-32 4
ENSP00000307633 FXMRP1_C_core PF12235 3e-32 5
ENSP00000307633 FXR_C1 PF16096 1.1e-38 6
ENSP00000419793 KH_9 PF17904 2.6e-35 1
ENSP00000418724 KH_9 PF17904 2.7e-18 1
ENSP00000417125 KH_9 PF17904 1.9e-13 1
ENSP00000418027 FXMRP1_C_core PF12235 1.5e-13 1
ENSP00000418027 FXR_C1 PF16096 7e-39 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35908416 Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury. Zhengping Hou 2022-08-01 EBioMedicine
36245599 Skeletal muscle and related protein expression as prognostic factors in thymic squamous cell carcinoma. Keita Nakanishi 2022-09-01 Journal of thoracic disease
32313943 Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins. Michael Backlund 2020-05-21 Nucleic acids research
36498797 Screening and Identification of Key Biomarkers in Metastatic Uveal Melanoma: Evidence from a Bioinformatic Analysis. Tan Wang 2022-12-05 Journal of clinical medicine
32193154 Upregulation of OIP5-AS1 Predicts Poor Prognosis and Contributes to Thyroid Cancer Cell Proliferation and Migration. Qiuli Li 2020-06-05 Molecular therapy. Nucleic acids
35886008 Identification of Antitumor miR-30e-5p Controlled Genes; Diagnostic and Prognostic Biomarkers for Head and Neck Squamous Cell Carcinoma. Chikashi Minemura 2022-07-09 Genes
21072162 Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2. A Melanie Adams-Cioaba 2010-11-02 PloS one
36749074 Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism. Zamaneh Hajikhezri 2023-02-28 Journal of virology
35666183 Integrative analysis and prediction of human R-loop binding proteins. Arun Kumar 2022-07-29 G3 (Bethesda, Md.)
36306353 Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells. Chandreyee Datta 2022-10-28 Science advances
7781595 FXR1, an autosomal homolog of the fragile X mental retardation gene. C M Siomi 1995-06-01 The EMBO journal
37180732 Study liquid-liquid phase separation with optical microscopy: A methodology review. Xiufeng Zhang 2023-06-01 APL bioengineering
34291416 Fragile X-Related Protein 1 (FXR1) Promotes Trophoblast Migration at Early Pregnancy via Downregulation of GDF-15 Expression. Wei Hong 2022-01-01 Reproductive sciences (Thousand Oaks, Calif.)
35294905 The RNA-binding protein fragile-X mental retardation autosomal 1 (FXR1) modulates glioma cells sensitivity to temozolomide by regulating ferroptosis. Yiting Wei 2022-05-07 Biochemical and biophysical research communications
30687136 Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects. Antonio Rampino 2018-01-01 Frontiers in psychiatry
32995776 Genes with 5' terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein. Shilpa Rao 2021-05-25 bioRxiv : the preprint server for biology
27229378 Regulation of monocyte induced cell migration by the RNA binding protein, FXR1. O O Le 2016-07-17 Cell cycle (Georgetown, Tex.)
23582851 Fragile hearts: new insights into translational control in cardiac muscle. C Daniela Zarnescu 2013-11-01 Trends in cardiovascular medicine
35887344 Amyloid Properties of the FXR1 Protein Are Conserved in Evolution of Vertebrates. E Maria Velizhanina 2022-07-20 International journal of molecular sciences
27606879 RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. Mrinmoyee Majumder 2016-09-01 PLoS genetics

Transcripts

Name Transcript ID bp Protein Translation ID
FXR1-208 ENST00000469882 570 119aa ENSP00000419793
FXR1-218 ENST00000484790 571 75aa ENSP00000417125
FXR1-206 ENST00000465551 572 94aa ENSP00000418724
FXR1-201 ENST00000305586 3277 536aa ENSP00000307633
FXR1-211 ENST00000475315 2341 54aa ENSP00000513935
FXR1-221 ENST00000491674 365 19aa ENSP00000419047
FXR1-223 ENST00000698793 5294 568aa ENSP00000513936
FXR1-224 ENST00000698794 3593 650aa ENSP00000513937
FXR1-202 ENST00000357559 8343 621aa ENSP00000350170
FXR1-213 ENST00000479176 541 No protein -
FXR1-220 ENST00000491062 1768 490aa ENSP00000420643
FXR1-207 ENST00000468861 1989 454aa ENSP00000420515
FXR1-203 ENST00000445140 2651 539aa ENSP00000388828
FXR1-209 ENST00000472339 2130 No protein -
FXR1-219 ENST00000484958 824 123aa ENSP00000419933
FXR1-214 ENST00000480918 1996 608aa ENSP00000418097
FXR1-217 ENST00000484042 562 151aa ENSP00000417513
FXR1-205 ENST00000461801 410 No protein -
FXR1-210 ENST00000473375 483 No protein -
FXR1-204 ENST00000461044 601 No protein -
FXR1-222 ENST00000498658 683 No protein -
FXR1-212 ENST00000476672 976 No protein -
FXR1-216 ENST00000482125 739 246aa ENSP00000418027
FXR1-215 ENST00000481383 909 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
8434Gallbladder Diseases8.11426262097292E-5-
86344Bipolar Disorder4E-626433762
86345Binge-Eating Disorder4E-626433762
95248Bipolar Disorder1E-626433762
95249Binge-Eating Disorder1E-626433762

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000114416homo_sapiensENSP0000035950666.613957.1203homo_sapiensENSP0000035017067.793958.132
ENSG00000114416homo_sapiensENSP0000025011369.68859.2868homo_sapiensENSP0000035017075.523364.2512

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000114416homo_sapiensENSP0000035017097.423597.2625nomascus_leucogenysENSNLEP0000002868791.52891.3767
ENSG00000114416homo_sapiensENSP00000350170100100pan_paniscusENSPPAP0000002989979.411879.4118
ENSG00000114416homo_sapiensENSP00000350170100100pongo_abeliiENSPPYP0000003145695.538595.5385
ENSG00000114416homo_sapiensENSP00000350170100100pan_troglodytesENSPTRP0000002694279.411879.4118
ENSG00000114416homo_sapiensENSP00000350170100100gorilla_gorillaENSGGOP0000003540779.820179.8201
ENSG00000114416homo_sapiensENSP0000035017097.906696.2963ornithorhynchus_anatinusENSOANP0000003906881.501380.1609
ENSG00000114416homo_sapiensENSP0000035017098.389797.1014sarcophilus_harrisiiENSSHAP0000003807789.985388.8071
ENSG00000114416homo_sapiensENSP0000035017072.946971.9807notamacropus_eugeniiENSMEUP000000043047574.0066
ENSG00000114416homo_sapiensENSP0000035017064.895364.4122choloepus_hoffmanniENSCHOP0000001140786.480785.8369
ENSG00000114416homo_sapiensENSP0000035017063.12456.6828dasypus_novemcinctusENSDNOP0000001875872.862565.4275
ENSG00000114416homo_sapiensENSP0000035017010099.6779dasypus_novemcinctusENSDNOP0000001478795.833395.5247
ENSG00000114416homo_sapiensENSP0000035017099.355998.0676erinaceus_europaeusENSEEUP0000000625599.355998.0676
ENSG00000114416homo_sapiensENSP0000035017089.21188.5668echinops_telfairiENSETEP0000000558898.401497.6909
ENSG00000114416homo_sapiensENSP0000035017099.83999.5169callithrix_jacchusENSCJAP0000002357295.67995.3704
ENSG00000114416homo_sapiensENSP00000350170100100cercocebus_atysENSCATP0000003625295.833395.8333
ENSG00000114416homo_sapiensENSP00000350170100100macaca_fascicularisENSMFAP0000000114478.015178.0151
ENSG00000114416homo_sapiensENSP00000350170100100macaca_mulattaENSMMUP0000003877377.819577.8195
ENSG00000114416homo_sapiensENSP00000350170100100macaca_nemestrinaENSMNEP0000001528395.833395.8333
ENSG00000114416homo_sapiensENSP00000350170100100papio_anubisENSPANP0000002400377.819577.8195
ENSG00000114416homo_sapiensENSP0000035017097.423597.2625mandrillus_leucophaeusENSMLEP0000003450091.52891.3767
ENSG00000114416homo_sapiensENSP0000035017099.83999.3559tursiops_truncatusENSTTRP0000001393710099.5161
ENSG00000114416homo_sapiensENSP0000035017010099.6779vulpes_vulpesENSVVUP0000000891095.833395.5247
ENSG00000114416homo_sapiensENSP0000035017099.194898.2287mus_spretusMGP_SPRETEiJ_P005956390.989790.1034
ENSG00000114416homo_sapiensENSP0000035017010099.5169equus_asinusENSEASP0000504319391.728291.2851
ENSG00000114416homo_sapiensENSP0000035017010099.5169capra_hircusENSCHIP0000001728595.833395.3704
ENSG00000114416homo_sapiensENSP0000035017099.516998.8728loxodonta_africanaENSLAFP0000002924491.285190.6942
ENSG00000114416homo_sapiensENSP0000035017086.151485.8293panthera_leoENSPLOP0000003065699.257998.8868
ENSG00000114416homo_sapiensENSP0000035017010099.5169panthera_leoENSPLOP0000002435410099.5169
ENSG00000114416homo_sapiensENSP0000035017010099.6779ailuropoda_melanoleucaENSAMEP0000004211795.833395.5247
ENSG00000114416homo_sapiensENSP0000035017010099.5169bos_indicus_hybridENSBIXP0000501456491.728291.2851
ENSG00000114416homo_sapiensENSP0000035017099.83999.1948oryctolagus_cuniculusENSOCUP0000004212679.385478.8732
ENSG00000114416homo_sapiensENSP0000035017010099.5169equus_caballusENSECAP0000002353988.968588.5387
ENSG00000114416homo_sapiensENSP0000035017010099.6779canis_lupus_familiarisENSCAFP0084502712495.833395.5247
ENSG00000114416homo_sapiensENSP0000035017010099.5169panthera_pardusENSPPRP0000001079010099.5169
ENSG00000114416homo_sapiensENSP0000035017010099.1948marmota_marmota_marmotaENSMMMP0000000377091.728290.9897
ENSG00000114416homo_sapiensENSP0000035017099.677999.3559balaenoptera_musculusENSBMSP0001000659010099.6769
ENSG00000114416homo_sapiensENSP0000035017081.642581.3204balaenoptera_musculusENSBMSP0001001807010099.6055
ENSG00000114416homo_sapiensENSP0000035017099.355999.0338cavia_porcellusENSCPOP0000002429291.137490.8419
ENSG00000114416homo_sapiensENSP0000035017099.83999.3559felis_catusENSFCAP0000006028910099.5161
ENSG00000114416homo_sapiensENSP0000035017086.312485.9903ursus_americanusENSUAMP0000000797510099.6269
ENSG00000114416homo_sapiensENSP0000035017095.974294.847monodelphis_domesticaENSMODP0000002662090.853789.7866
ENSG00000114416homo_sapiensENSP0000035017010099.5169bison_bison_bisonENSBBBP0000000781810099.5169
ENSG00000114416homo_sapiensENSP0000035017010099.6779monodon_monocerosENSMMNP0001500120810099.6779
ENSG00000114416homo_sapiensENSP0000035017099.677999.3559sus_scrofaENSSSCP0000002340791.432891.1374
ENSG00000114416homo_sapiensENSP0000035017082.930881.1594microcebus_murinusENSMICP0000003052595.903293.8548
ENSG00000114416homo_sapiensENSP0000035017094.84794.525microcebus_murinusENSMICP0000005145591.035590.7264
ENSG00000114416homo_sapiensENSP0000035017068.115963.124octodon_degusENSODEP0000000125884.262978.0876
ENSG00000114416homo_sapiensENSP0000035017099.033898.7118octodon_degusENSODEP0000000135590.841990.5465
ENSG00000114416homo_sapiensENSP0000035017078.260977.1337octodon_degusENSODEP0000000828791.011289.7004
ENSG00000114416homo_sapiensENSP0000035017094.041993.7198jaculus_jaculusENSJJAP0000001772490.542690.2326
ENSG00000114416homo_sapiensENSP0000035017093.397792.9147ovis_aries_rambouilletENSOARP0002000773589.230888.7692
ENSG00000114416homo_sapiensENSP0000035017086.312485.9903ursus_maritimusENSUMAP0000000934510099.6269
ENSG00000114416homo_sapiensENSP0000035017091.626490.6602ochotona_princepsENSOPRP0000000844694.518393.5216
ENSG00000114416homo_sapiensENSP0000035017010099.6779delphinapterus_leucasENSDLEP0000001625410099.6779
ENSG00000114416homo_sapiensENSP0000035017010099.6779physeter_catodonENSPCTP0000500551092.686692.3881
ENSG00000114416homo_sapiensENSP0000035017099.194898.2287mus_caroliMGP_CAROLIEiJ_P005730690.989790.1034
ENSG00000114416homo_sapiensENSP0000035017099.194898.0676mus_musculusENSMUSP0000000162090.989789.9557
ENSG00000114416homo_sapiensENSP0000035017085.507284.219dipodomys_ordiiENSDORP0000002414888.352787.0216
ENSG00000114416homo_sapiensENSP0000035017010099.6779mustela_putorius_furoENSMPUP0000000230995.833395.5247
ENSG00000114416homo_sapiensENSP0000035017099.516999.3559aotus_nancymaaeENSANAP0000001631688.41288.269
ENSG00000114416homo_sapiensENSP0000035017094.041993.3977saimiri_boliviensis_boliviensisENSSBOP0000003505889.708189.0937
ENSG00000114416homo_sapiensENSP0000035017097.101496.7794vicugna_pacosENSVPAP0000000312810099.6683
ENSG00000114416homo_sapiensENSP00000350170100100chlorocebus_sabaeusENSCSAP0000000934895.833395.8333
ENSG00000114416homo_sapiensENSP0000035017055.716655.5556tupaia_belangeriENSTBEP0000000637364.915664.728
ENSG00000114416homo_sapiensENSP0000035017099.194898.3897mesocricetus_auratusENSMAUP0000000165590.989790.2511
ENSG00000114416homo_sapiensENSP0000035017099.83999.3559phocoena_sinusENSPSNP0000000232797.791897.3186
ENSG00000114416homo_sapiensENSP0000035017010099.6779camelus_dromedariusENSCDRP0000500209695.833395.5247
ENSG00000114416homo_sapiensENSP0000035017097.423596.7794carlito_syrichtaENSTSYP0000002152791.389790.7855
ENSG00000114416homo_sapiensENSP0000035017010099.5169panthera_tigris_altaicaENSPTIP0000002328110099.5169
ENSG00000114416homo_sapiensENSP0000035017099.355998.5507rattus_norvegicusENSRNOP0000009571191.137490.3988
ENSG00000114416homo_sapiensENSP0000035017092.109591.9485prolemur_simusENSPSMP0000001666891.961491.8006
ENSG00000114416homo_sapiensENSP0000035017097.584596.2963microtus_ochrogasterENSMOCP0000001985988.986887.812
ENSG00000114416homo_sapiensENSP0000035017076.489576.3285sorex_araneusENSSARP0000001081678.642478.4768
ENSG00000114416homo_sapiensENSP0000035017096.457395.8132peromyscus_maniculatus_bairdiiENSPEMP0000001275988.478687.8877
ENSG00000114416homo_sapiensENSP0000035017098.550798.0676bos_mutusENSBMUP0000002333710099.5098
ENSG00000114416homo_sapiensENSP0000035017099.355998.3897mus_spicilegusENSMSIP0000001378291.137490.2511
ENSG00000114416homo_sapiensENSP0000035017099.194898.3897cricetulus_griseus_chok1gshdENSCGRP0000102794395.061794.2901
ENSG00000114416homo_sapiensENSP0000035017084.541184.38pteropus_vampyrusENSPVAP0000000266892.920492.7434
ENSG00000114416homo_sapiensENSP0000035017097.423596.9404myotis_lucifugusENSMLUP0000000625391.52891.0741
ENSG00000114416homo_sapiensENSP0000035017098.228797.1014vombatus_ursinusENSVURP0001001569297.913396.7897
ENSG00000114416homo_sapiensENSP0000035017099.83999.3559rhinolophus_ferrumequinumENSRFEP0001003235195.67995.216
ENSG00000114416homo_sapiensENSP0000035017010099.5169neovison_visonENSNVIP0000002141810099.5169
ENSG00000114416homo_sapiensENSP0000035017010099.5169bos_taurusENSBTAP0000006881795.833395.3704
ENSG00000114416homo_sapiensENSP0000035017099.516999.0338heterocephalus_glaber_femaleENSHGLP0000002644491.285190.8419
ENSG00000114416homo_sapiensENSP0000035017089.855189.533rhinopithecus_bietiENSRBIP0000002619494.89894.5578
ENSG00000114416homo_sapiensENSP0000035017010099.6779canis_lupus_dingoENSCAFP0002003017810099.6779
ENSG00000114416homo_sapiensENSP0000035017010099.1948sciurus_vulgarisENSSVLP0000500720610099.1948
ENSG00000114416homo_sapiensENSP0000035017094.363993.3977phascolarctos_cinereusENSPCIP0000003559392.57591.6272
ENSG00000114416homo_sapiensENSP0000035017047.987146.8599procavia_capensisENSPCAP0000001391849.337748.1788
ENSG00000114416homo_sapiensENSP0000035017097.745695.9742nannospalax_galiliENSNGAP0000002307190.059388.4273
ENSG00000114416homo_sapiensENSP0000035017010099.5169bos_grunniensENSBGRP0000000333195.833395.3704
ENSG00000114416homo_sapiensENSP0000035017099.033898.8728chinchilla_lanigeraENSCLAP0000002070190.976390.8284
ENSG00000114416homo_sapiensENSP0000035017010099.5169cervus_hanglu_yarkandensisENSCHYP0000002393195.833395.3704
ENSG00000114416homo_sapiensENSP0000035017099.677999.3559catagonus_wagneriENSCWAP0000001431399.677999.3559
ENSG00000114416homo_sapiensENSP0000035017010099.1948ictidomys_tridecemlineatusENSSTOP0000001871191.728290.9897
ENSG00000114416homo_sapiensENSP0000035017010099.6779otolemur_garnettiiENSOGAP0000000784710099.6779
ENSG00000114416homo_sapiensENSP0000035017092.431691.3043cebus_imitatorENSCCAP0000001458288.854587.7709
ENSG00000114416homo_sapiensENSP0000035017010099.1948urocitellus_parryiiENSUPAP0001002859795.833395.0617
ENSG00000114416homo_sapiensENSP0000035017072.463871.9807moschus_moschiferusENSMMSP0000002298599.118998.4582
ENSG00000114416homo_sapiensENSP0000035017010099.5169moschus_moschiferusENSMMSP0000000193710099.5169
ENSG00000114416homo_sapiensENSP00000350170100100rhinopithecus_roxellanaENSRROP0000002139195.833395.8333
ENSG00000114416homo_sapiensENSP0000035017099.355998.3897mus_pahariMGP_PahariEiJ_P006829491.137490.2511
ENSG00000114416homo_sapiensENSP0000035017094.52593.7198propithecus_coquereliENSPCOP0000001661389.209788.4498
ENSG00000114416homo_sapiensENSP0000035017057.64940.9018drosophila_melanogasterFBpp030044549.108434.8423
ENSG00000114416homo_sapiensENSP0000035017047.987135.2657ciona_intestinalisENSCINP0000001738863.675246.7949
ENSG00000114416homo_sapiensENSP0000035017085.668377.9388callorhinchus_miliiENSCMIP0000003283477.777870.7602
ENSG00000114416homo_sapiensENSP0000035017091.465483.5749latimeria_chalumnaeENSLACP0000001282183.652476.4359
ENSG00000114416homo_sapiensENSP0000035017089.855182.4477lepisosteus_oculatusENSLOCP0000000065281.698474.9634
ENSG00000114416homo_sapiensENSP0000035017087.439678.0998clupea_harengusENSCHAP0000004318274.896666.8966
ENSG00000114416homo_sapiensENSP0000035017083.091872.6248danio_rerioENSDARP000001241928069.9225
ENSG00000114416homo_sapiensENSP0000035017086.634575.5233carassius_auratusENSCARP0000010431782.137471.6031
ENSG00000114416homo_sapiensENSP0000035017086.634576.3285carassius_auratusENSCARP0000003362180.780871.1712
ENSG00000114416homo_sapiensENSP0000035017085.990376.1675astyanax_mexicanusENSAMXP0000005432979.582770.4918
ENSG00000114416homo_sapiensENSP0000035017081.964670.3704ictalurus_punctatusENSIPUP0000003672676.541465.7143
ENSG00000114416homo_sapiensENSP0000035017079.388167.7939esox_luciusENSELUP0000007329274.471363.5952
ENSG00000114416homo_sapiensENSP0000035017084.05873.1079electrophorus_electricusENSEEEP0000003580477.333367.2593
ENSG00000114416homo_sapiensENSP0000035017060.064450.2415oncorhynchus_kisutchENSOKIP0000510390677.870665.1357
ENSG00000114416homo_sapiensENSP0000035017084.541173.913oncorhynchus_kisutchENSOKIP0000507920177.54867.7991
ENSG00000114416homo_sapiensENSP0000035017080.032269.5652oncorhynchus_mykissENSOMYP0000003252776.93566.8731
ENSG00000114416homo_sapiensENSP0000035017074.235165.2174oncorhynchus_mykissENSOMYP0000005671380.594470.8042
ENSG00000114416homo_sapiensENSP0000035017054.428348.1481oncorhynchus_mykissENSOMYP0000012593172.688264.3011
ENSG00000114416homo_sapiensENSP0000035017048.792343.8003oncorhynchus_mykissENSOMYP0000011582678.497470.4663
ENSG00000114416homo_sapiensENSP0000035017084.05873.752salmo_salarENSSSAP0000012765177.333367.8519
ENSG00000114416homo_sapiensENSP0000035017021.578117.7134salmo_salarENSSSAP0000017557167.336755.2764
ENSG00000114416homo_sapiensENSP0000035017079.710170.0483salmo_truttaENSSTUP0000009054876.153866.9231
ENSG00000114416homo_sapiensENSP0000035017072.302762.4799gadus_morhuaENSGMOP0000004128267.824858.6103
ENSG00000114416homo_sapiensENSP0000035017032.206128.3414fundulus_heteroclitusENSFHEP0000000288977.220167.9537
ENSG00000114416homo_sapiensENSP0000035017025.764922.2222fundulus_heteroclitusENSFHEP0000000290286.486574.5946
ENSG00000114416homo_sapiensENSP0000035017075.040365.5395poecilia_reticulataENSPREP0000003355581.611271.2785
ENSG00000114416homo_sapiensENSP0000035017083.574971.9807xiphophorus_maculatusENSXMAP0000000068479.969268.8752
ENSG00000114416homo_sapiensENSP0000035017082.447771.8196oryzias_latipesENSORLP0000001477775.40565.6848
ENSG00000114416homo_sapiensENSP0000035017075.040365.2174cyclopterus_lumpusENSCLMP0000503357374.919665.1125
ENSG00000114416homo_sapiensENSP0000035017083.896971.9807oreochromis_niloticusENSONIP0000003938270.980960.8992
ENSG00000114416homo_sapiensENSP0000035017084.05872.1417haplochromis_burtoniENSHBUP0000000359971.117261.0354
ENSG00000114416homo_sapiensENSP0000035017084.05871.8196astatotilapia_callipteraENSACLP0000003825073.728862.9944
ENSG00000114416homo_sapiensENSP0000035017084.21971.9807sparus_aurataENSSAUP0001002436771.545861.1491
ENSG00000114416homo_sapiensENSP0000035017084.3872.7858lates_calcariferENSLCAP0001000517270.906661.1637
ENSG00000114416homo_sapiensENSP0000035017093.558888.0837xenopus_tropicalisENSXETP0000004215486.201881.1573
ENSG00000114416homo_sapiensENSP0000035017097.423595.3301chrysemys_picta_belliiENSCPBP0000000023689.23387.3156
ENSG00000114416homo_sapiensENSP0000035017082.286680.0322sphenodon_punctatusENSSPUP0000001883696.233593.597
ENSG00000114416homo_sapiensENSP0000035017092.270588.5668crocodylus_porosusENSCPRP0000501501585.267981.8452
ENSG00000114416homo_sapiensENSP0000035017094.202989.533laticauda_laticaudataENSLLTP0000002162585.903181.6446
ENSG00000114416homo_sapiensENSP0000035017095.330191.4654notechis_scutatusENSNSUP0000000569891.076987.3846
ENSG00000114416homo_sapiensENSP0000035017095.491191.6264pseudonaja_textilisENSPTXP0000002533087.592384.0473
ENSG00000114416homo_sapiensENSP0000035017096.779493.3977anas_platyrhynchos_platyrhynchosENSAPLP0000002851992.461589.2308
ENSG00000114416homo_sapiensENSP0000035017096.296392.7536gallus_gallusENSGALP0001002329988.330985.0812
ENSG00000114416homo_sapiensENSP0000035017093.236788.8889meleagris_gallopavoENSMGAP0000000995682.127778.2979
ENSG00000114416homo_sapiensENSP0000035017091.304387.6006serinus_canariaENSSCAP0000001719087.096883.5638
ENSG00000114416homo_sapiensENSP0000035017096.618492.9147parus_majorENSPMJP0000000271681.300878.1843
ENSG00000114416homo_sapiensENSP0000035017092.914789.533anolis_carolinensisENSACAP0000000392586.766983.609
ENSG00000114416homo_sapiensENSP0000035017075.362366.1836neolamprologus_brichardiENSNBRP0000002763877.611968.1592
ENSG00000114416homo_sapiensENSP0000035017094.202990.3382naja_najaENSNNAP0000001528286.410682.8656
ENSG00000114416homo_sapiensENSP0000035017095.330192.2705podarcis_muralisENSPMRP0000000619387.315684.5133
ENSG00000114416homo_sapiensENSP0000035017091.948587.9227geospiza_fortisENSGFOP0000001037487.308983.4862
ENSG00000114416homo_sapiensENSP0000035017096.457392.9147taeniopygia_guttataENSTGUP0000001091288.478685.229
ENSG00000114416homo_sapiensENSP0000035017067.632960.7085erpetoichthys_calabaricusENSECRP0000001866084.677476.0081
ENSG00000114416homo_sapiensENSP0000035017080.032268.1159kryptolebias_marmoratusENSKMAP0000000621775.993964.6789
ENSG00000114416homo_sapiensENSP0000035017095.813292.1095salvator_merianaeENSSMRP0000003078587.758184.3658
ENSG00000114416homo_sapiensENSP0000035017083.735971.9807oryzias_javanicusENSOJAP0000004533276.134765.4466
ENSG00000114416homo_sapiensENSP0000035017076.489566.1836amphilophus_citrinellusENSACIP0000003017780.508569.661
ENSG00000114416homo_sapiensENSP0000035017076.972666.3446dicentrarchus_labraxENSDLAP0000507017874.223663.9752
ENSG00000114416homo_sapiensENSP0000035017080.515370.2093amphiprion_perculaENSAPEP0000002104779.617869.4268
ENSG00000114416homo_sapiensENSP0000035017082.769771.8196oryzias_sinensisENSOSIP0000002856075.923265.8789
ENSG00000114416homo_sapiensENSP0000035017093.397790.6602pelodiscus_sinensisENSPSIP0000000843586.309583.7798
ENSG00000114416homo_sapiensENSP0000035017097.262595.1691gopherus_evgoodeiENSGEVP0000501041492.780390.7834
ENSG00000114416homo_sapiensENSP0000035017093.880890.9823chelonoidis_abingdoniiENSCABP0000002672086.75684.0774
ENSG00000114416homo_sapiensENSP0000035017085.346273.2689seriola_dumeriliENSSDUP0000002280074.438263.9045
ENSG00000114416homo_sapiensENSP0000035017080.193268.277cottoperca_gobioENSCGOP0000000424673.887262.908
ENSG00000114416homo_sapiensENSP0000035017090.499286.7955struthio_camelus_australisENSSCUP0000002376987.538983.9564
ENSG00000114416homo_sapiensENSP0000035017096.779493.3977anser_brachyrhynchusENSABRP0000000499892.461589.2308
ENSG00000114416homo_sapiensENSP0000035017081.159469.4042gasterosteus_aculeatusENSGACP000000080257564.1369
ENSG00000114416homo_sapiensENSP0000035017085.346272.7858cynoglossus_semilaevisENSCSEP0000000240575.177364.1135
ENSG00000114416homo_sapiensENSP0000035017084.05872.7858poecilia_formosaENSPFOP0000001481577.218966.8639
ENSG00000114416homo_sapiensENSP0000035017085.507273.2689myripristis_murdjanENSMMDP0000504113678.434367.2083
ENSG00000114416homo_sapiensENSP0000035017083.091871.8196sander_luciopercaENSSLUP0000002157267.362958.2245
ENSG00000114416homo_sapiensENSP0000035017096.618493.2367strigops_habroptilaENSSHBP0000501387988.626385.5244
ENSG00000114416homo_sapiensENSP0000035017079.549168.7601amphiprion_ocellarisENSAOCP0000003087182.608771.4047
ENSG00000114416homo_sapiensENSP0000035017097.423595.3301terrapene_carolina_triunguisENSTMTP0000001378292.933990.937
ENSG00000114416homo_sapiensENSP0000035017084.3874.0741hucho_huchoENSHHUP0000005596477.400367.9468
ENSG00000114416homo_sapiensENSP0000035017049.919542.351hucho_huchoENSHHUP0000008650679.691567.6093
ENSG00000114416homo_sapiensENSP0000035017082.286671.1755betta_splendensENSBSLP0000001468671.66961.9916
ENSG00000114416homo_sapiensENSP0000035017085.829375.3623pygocentrus_nattereriENSPNAP0000001516277.696868.2216
ENSG00000114416homo_sapiensENSP0000035017083.735971.6586anabas_testudineusENSATEP0000003910570.175460.054
ENSG00000114416homo_sapiensENSP0000035017035.104724.3156ciona_savignyiENSCSAVP0000001264566.871246.319
ENSG00000114416homo_sapiensENSP0000035017080.515370.5314seriola_lalandi_dorsalisENSSLDP0000002357282.781572.5166
ENSG00000114416homo_sapiensENSP0000035017079.871267.7939labrus_bergyltaENSLBEP0000001526870.958560.2289
ENSG00000114416homo_sapiensENSP0000035017084.21971.9807labrus_bergyltaENSLBEP0000001960170.390360.1615
ENSG00000114416homo_sapiensENSP0000035017083.896971.8196pundamilia_nyerereiENSPNYP0000001861175.507264.6377
ENSG00000114416homo_sapiensENSP0000035017085.346273.913mastacembelus_armatusENSMAMP0000003953276.589666.3295
ENSG00000114416homo_sapiensENSP0000035017086.151473.591stegastes_partitusENSSPAP0000001397677.200665.9452
ENSG00000114416homo_sapiensENSP0000035017037.198132.2061oncorhynchus_tshawytschaENSOTSP0000506510289.189277.2201
ENSG00000114416homo_sapiensENSP0000035017059.420351.6908oncorhynchus_tshawytschaENSOTSP0000504786777.684267.5789
ENSG00000114416homo_sapiensENSP0000035017033.494429.7907oncorhynchus_tshawytschaENSOTSP0000506510681.889872.8346
ENSG00000114416homo_sapiensENSP0000035017085.507273.1079acanthochromis_polyacanthusENSAPOP0000001414576.845265.7019
ENSG00000114416homo_sapiensENSP0000035017096.779493.3977aquila_chrysaetos_chrysaetosENSACCP0002000147592.461589.2308
ENSG00000114416homo_sapiensENSP0000035017084.21971.1755nothobranchius_furzeriENSNFUP0001503485748.381140.8881
ENSG00000114416homo_sapiensENSP0000035017084.3872.4638cyprinodon_variegatusENSCVAP0000000169274.326263.8298
ENSG00000114416homo_sapiensENSP0000035017086.151475.0403denticeps_clupeoidesENSDCDP0000006358178.102268.0292
ENSG00000114416homo_sapiensENSP0000035017084.541172.7858larimichthys_croceaENSLCRP0000503672374.468164.1135
ENSG00000114416homo_sapiensENSP0000035017081.320468.438takifugu_rubripesENSTRUP0000006072273.615261.9534
ENSG00000114416homo_sapiensENSP0000035017094.84791.1433ficedula_albicollisENSFALP0000000865184.50581.2052
ENSG00000114416homo_sapiensENSP0000035017069.726260.3865hippocampus_comesENSHCOP0000000812276.909466.6075
ENSG00000114416homo_sapiensENSP0000035017039.774633.8164hippocampus_comesENSHCOP0000002245487.900474.7331
ENSG00000114416homo_sapiensENSP0000035017057.97150.0805hippocampus_comesENSHCOP0000002248177.253266.7382
ENSG00000114416homo_sapiensENSP0000035017086.634575.6844cyprinus_carpio_carpioENSCCRP0000009252781.391871.1044
ENSG00000114416homo_sapiensENSP0000035017086.795576.6506cyprinus_carpio_carpioENSCCRP0000017753583.825874.028
ENSG00000114416homo_sapiensENSP0000035017096.457392.7536coturnix_japonicaENSCJPP0000501745092.153888.6154
ENSG00000114416homo_sapiensENSP0000035017083.896972.6248poecilia_latipinnaENSPLAP0000003130477.185266.8148
ENSG00000114416homo_sapiensENSP0000035017083.735973.913sinocyclocheilus_grahamiENSSGRP0000010372279.877170.5069
ENSG00000114416homo_sapiensENSP0000035017083.896974.3961sinocyclocheilus_grahamiENSSGRP0000001608779.54270.5343
ENSG00000114416homo_sapiensENSP0000035017083.896971.8196maylandia_zebraENSMZEP0000502090575.726764.8256
ENSG00000114416homo_sapiensENSP0000035017080.676367.6329tetraodon_nigroviridisENSTNIP0000000639073.568361.674
ENSG00000114416homo_sapiensENSP0000035017015.629.82287tetraodon_nigroviridisENSTNIP0000000960862.179539.1026
ENSG00000114416homo_sapiensENSP0000035017086.634575.6844paramormyrops_kingsleyaeENSPKIP0000001525278.65568.7134
ENSG00000114416homo_sapiensENSP0000035017077.455765.0564paramormyrops_kingsleyaeENSPKIP0000003499674.343162.442
ENSG00000114416homo_sapiensENSP0000035017074.879263.124scleropages_formosusENSSFOP0001505704572.09360.7752
ENSG00000114416homo_sapiensENSP0000035017087.117678.4219scleropages_formosusENSSFOP0001507868379.209471.3031
ENSG00000114416homo_sapiensENSP0000035017090.177183.8969leptobrachium_leishanenseENSLLEP0000004712082.595976.8437
ENSG00000114416homo_sapiensENSP0000035017061.352758.6151leptobrachium_leishanenseENSLLEP0000003895285.61881.7978
ENSG00000114416homo_sapiensENSP0000035017021.900219.6457leptobrachium_leishanenseENSLLEP0000000640473.91366.3043
ENSG00000114416homo_sapiensENSP0000035017084.05872.1417scophthalmus_maximusENSSMAP0000003141570.067160.1342
ENSG00000114416homo_sapiensENSP0000035017083.091871.6586oryzias_melastigmaENSOMEP0000002858275.54965.1537

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000381involved_in regulation of alternative mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0001934involved_in positive regulation of protein phosphorylation1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding2HDA,IDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005635is_active_in nuclear envelope1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IDA,IMPHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005844part_of polysome1IBAHomo_sapiens(9606)Component
GO:0006915involved_in apoptotic process1TASHomo_sapiens(9606)Process
GO:0007286involved_in spermatid development1ISSHomo_sapiens(9606)Process
GO:0007517involved_in muscle organ development1IMPHomo_sapiens(9606)Process
GO:0010494is_active_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0014069is_active_in postsynaptic density1IBAHomo_sapiens(9606)Component
GO:0016020located_in membrane2HDA,IBAHomo_sapiens(9606)Component
GO:0017148involved_in negative regulation of translation1IBAHomo_sapiens(9606)Process
GO:0021542involved_in dentate gyrus development1ISSHomo_sapiens(9606)Process
GO:0030424is_active_in axon1IBAHomo_sapiens(9606)Component
GO:0030426is_active_in growth cone1IBAHomo_sapiens(9606)Component
GO:0032720involved_in negative regulation of tumor necrosis factor production1ISSHomo_sapiens(9606)Process
GO:0033592enables RNA strand annealing activity1IDAHomo_sapiens(9606)Function
GO:0035925enables mRNA 3-UTR AU-rich region binding1IDAHomo_sapiens(9606)Function
GO:0036464is_active_in cytoplasmic ribonucleoprotein granule2IBA,IDAHomo_sapiens(9606)Component
GO:0042803enables protein homodimerization activity2IBA,IDAHomo_sapiens(9606)Function
GO:0043025is_active_in neuronal cell body1IBAHomo_sapiens(9606)Component
GO:0043034located_in costamere1IEAHomo_sapiens(9606)Component
GO:0043197is_active_in dendritic spine1IBAHomo_sapiens(9606)Component
GO:0043232is_active_in intracellular non-membrane-bounded organelle1ISSHomo_sapiens(9606)Component
GO:0043488involved_in regulation of mRNA stability1IBAHomo_sapiens(9606)Process
GO:0044326is_active_in dendritic spine neck1IBAHomo_sapiens(9606)Component
GO:0045182enables translation regulator activity1IBAHomo_sapiens(9606)Function
GO:0045187involved_in regulation of circadian sleep/wake cycle, sleep1ISSHomo_sapiens(9606)Process
GO:0045727involved_in positive regulation of translation2IBA,IDAHomo_sapiens(9606)Process
GO:0046982enables protein heterodimerization activity1IDAHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0050728involved_in negative regulation of inflammatory response1IDAHomo_sapiens(9606)Process
GO:0050767involved_in regulation of neurogenesis1ISSHomo_sapiens(9606)Process
GO:0051292involved_in nuclear pore complex assembly1IDAHomo_sapiens(9606)Process
GO:0051489involved_in regulation of filopodium assembly1IBAHomo_sapiens(9606)Process
GO:0051664involved_in nuclear pore localization1IDAHomo_sapiens(9606)Process
GO:0051966involved_in regulation of synaptic transmission, glutamatergic1ISSHomo_sapiens(9606)Process
GO:0060538involved_in skeletal muscle organ development1IMPHomo_sapiens(9606)Process
GO:0061157involved_in mRNA destabilization1IDAHomo_sapiens(9606)Process
GO:0098793is_active_in presynapse1IBAHomo_sapiens(9606)Component
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0140693enables molecular condensate scaffold activity1ISSHomo_sapiens(9606)Function
GO:0140694involved_in non-membrane-bounded organelle assembly1ISSHomo_sapiens(9606)Process
GO:1900272involved_in negative regulation of long-term synaptic potentiation1ISSHomo_sapiens(9606)Process
GO:1902737is_active_in dendritic filopodium1IBAHomo_sapiens(9606)Component
GO:2000637involved_in positive regulation of miRNA-mediated gene silencing1IDAHomo_sapiens(9606)Process

Expression