Ensembl ID
ENSG00000114416
Gene ID
8087
Accession
4023
Gene Symbol
FXR1
Alias
FXR1P;CMYP9A;CMYP9B;MYOPMIL;MYORIBF
Full Name
FMR1 autosomal homolog 1
Position
3 : 180868141 - 180982753
Length
114613 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ENSG00000114416 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000114416
FXR1
1.58
1.90e-47
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000114416
FXR1
tumour
17868361
ENSG00000114416
FXR1
tumors
18476518
ENSG00000114416
FXR1
tumors
20126410
ENSG00000114416
FXR1
tumour
20491901
ENSG00000114416
FXR1
ovarian cancer
21426769
ENSG00000114416
FXR1
breast cancer
22446932
ENSG00000114416
FXR1
tumor
23881279
ENSG00000114416
FXR1
cancer
25484917
ENSG00000114416
FXR1
cancers
25733852
ENSG00000114416
FXR1
colorectal cancer
26404134
ENSG00000114416
FXR1
cancer
26484266
ENSG00000114416
FXR1
tumors
26513889
ENSG00000114416
FXR1
tumor
27186987
ENSG00000114416
FXR1
cancer
27229378
ENSG00000114416
FXR1
tumor
27606879
ENSG00000114416
FXR1
ovarian cancer
27788745
ENSG00000114416
FXR1
tumor
27812105
ENSG00000114416
FXR1
ovarian cancer
28190310
ENSG00000114416
FXR1
breast tumors
28387221
ENSG00000114416
FXR1
cancer
28767039
ENSG00000114416
FXR1
tumors
29608406
ENSG00000114416
FXR1
tumour
29852926
ENSG00000114416
FXR1
tumor
30691465
ENSG00000114416
FXR1
prostate cancer
30746571
ENSG00000114416
FXR1
Squamous Cell Cancer
30755307
ENSG00000114416
FXR1
Wilms tumor
30894247
ENSG00000114416
FXR1
cancers
31310629
ENSG00000114416
FXR1
tumors
31555743
ENSG00000114416
FXR1
oral cancer
31940341
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000114416
FXR1
MESO
0.039
low
show
ENSG00000114416
FXR1
SARC
0.0037
high
show
ENSG00000114416
FXR1
UVM
0.00059
low
show
ENSG00000114416
FXR1
PAAD
0.00022
high
show
ENSG00000114416
FXR1
UCEC
4e-04
high
show
ENSG00000114416
FXR1
ACC
0.041
high
show
ENSG00000114416
FXR1
LGG
0.035
low
show
ENSG00000114416
FXR1
LUSC
0.026
low
show
ENSG00000114416
FXR1
HNSC
0.0016
high
show
ENSG00000114416
FXR1
READ
0.045
low
show
ENSG00000114416
FXR1
KICH
0.012
high
show
ENSG00000114416
FXR1
LUAD
0.0015
high
show
ENSG00000114416
FXR1
COAD
0.016
high
show
ENSG00000114416
FXR1
OV
0.043
low
show
ENSG00000114416
FXR1
DLBC
0.047
low
show
ENSG00000114416
FXR1
KIRC
0.00025
high
show
ENSG00000114416
FXR1
PRAD
0.011
high
show
ENSG00000114416
FXR1
BLCA
0.013
high
show
ENSG00000114416
FXR1
LAML
0.0017
low
show
ENSG00000114416
FXR1
GBM
0.0062
low
show
ENSG00000114416
FXR1
SKCM
0.0097
low
show
ENSG00000114416
FXR1
CESC
0.013
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000114416
FXR1
LUSC
Amp
176.830807
1.971177
1.388964
0.906188
ENSG00000114416
FXR1
LUAD
Amp
1.936298
0.148072
0.450957
0.279070
ENSG00000114416
FXR1
LGG
Amp
2.109868
0.064507
0.891625
0.037037
ENSG00000114416
FXR1
CESC
Amp
30.177646
0.711254
1.098831
0.752542
ENSG00000114416
FXR1
UCS
Amp
2.481176
0.760368
0.962768
0.625000
ENSG00000114416
FXR1
SARC
Del
0.672819
0.119218
0.472153
0.194553
ENSG00000114416
FXR1
GBM
Amp
11.923158
0.215194
0.728999
0.175043
ENSG00000114416
FXR1
ESCA
Amp
14.151099
0.812192
0.921992
0.652174
ENSG00000114416
FXR1
HNSC
Amp
53.067501
0.728343
0.852832
0.720307
ENSG00000114416
FXR1
LIHC
Amp
0.740495
0.112968
0.506558
0.164865
ENSG00000114416
FXR1
PCPG
Del
2.353073
0.091557
0.639075
0.580247
ENSG00000114416
FXR1
TGCT
Amp
2.684102
0.207373
0.518652
0.320000
ENSG00000114416
FXR1
BLCA
Amp
1.317556
0.187080
0.492571
0.536765
ENSG00000114416
FXR1
BRCA
Amp
7.792108
0.242917
0.592043
0.303704
ENSG00000114416
FXR1
STAD
Amp
5.361000
0.244733
0.510800
0.351474
ENSG00000114416
FXR1
PRAD
Amp
0.829131
0.047678
0.398334
0.140244
ENSG00000114416
FXR1
UCEC
Amp
22.746430
0.380384
0.851723
0.285714
ENSG00000114416
FXR1
KIRC
Amp
2.220857
0.049849
0.399031
0.162879
ENSG00000114416
FXR1
OV
Amp
61.024666
1.147416
0.999798
0.784111
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