Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_40

Description

Ensembl ID ENSG00000112081 Gene ID 6428 Accession 10785
Symbol SRSF3 Alias SFRS3;SRp20 Full Name serine and arginine rich splicing factor 3
Status Confidence Length 11248 bases Strand Plus strand
Position 6 : 36594353 - 36605600 RNA binding domain RRM_1
Summary The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression