RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	snoRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000111405	Gene ID	8909	Accession	14369
Symbol	ENDOU	Alias	P11;PP11;PRSS26	Full Name	endonuclease, poly(U) specific
Status	Confidence	Length	15834 bases	Strand	Minus strand
Position	12 : 47709734 - 47725567	RNA binding domain	XendoU
Summary	This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2020]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000445004	XendoU	PF09412	3.5e-97	1
ENSP00000229003	XendoU	PF09412	4.2e-97	1
ENSP00000397679	XendoU	PF09412	5.7e-97	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
33614471	Integrated Analysis Reveals ENDOU as a Biomarker in Head and Neck Squamous Cell Carcinoma Progression.	Chengzhi Xu	2020-01-01	Frontiers in oncology
34857990	Upregulation of ENDOU in cytotrophoblasts from placenta complicated with preeclampsia and fetal growth restriction.	Masataka Nomoto	2021-11-01	Journal of clinical biochemistry and nutrition
33888706	Proteomics of protein trafficking by in vivo tissue-specific labeling.	A Ilia Droujinine	2021-04-22	Nature communications
29307596	An 'Old' protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses.	Xufang Deng	2018-04-01	Virology
32304108	Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.	Youngchang Kim	2020-07-01	Protein science : a publication of the Protein Society
35498548	Applying polypharmacology approach for drug repurposing for SARS-CoV2.	Esther Jamir	2022-01-01	Journal of chemical sciences (Bangalore, India)
33627668	The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans.	Wenjing Qi	2021-02-24	Nature communications
33504779	Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics.	C Monica Pillon	2021-01-27	Nature communications
35087058	Structural biology of SARS-CoV-2: open the door for novel therapies.	Weizhu Yan	2022-01-27	Signal transduction and targeted therapy
27712628	The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.	J E Snijder	2016-01-01	Advances in virus research

Name	Transcript ID	bp	Protein	Translation ID
ENDOU-201	ENST00000229003	2332	369aa	ENSP00000229003
ENDOU-202	ENST00000422538	2378	410aa	ENSP00000397679
ENDOU-203	ENST00000545824	1513	347aa	ENSP00000445004
ENDOU-204	ENST00000551186	652	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000111405

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000111405	homo_sapiens	ENSP00000397679	98.2927	96.5854	nomascus_leucogenys	ENSNLEP00000021758	98.0535	96.3504
ENSG00000111405	homo_sapiens	ENSP00000397679	94.3902	93.9024	pan_paniscus	ENSPPAP00000027580	89.3764	88.9146
ENSG00000111405	homo_sapiens	ENSP00000397679	98.7805	97.8049	pongo_abelii	ENSPPYP00000034619	98.5401	97.5669
ENSG00000111405	homo_sapiens	ENSP00000397679	99.7561	99.7561	pan_troglodytes	ENSPTRP00000008312	99.5134	99.5134
ENSG00000111405	homo_sapiens	ENSP00000397679	99.5122	98.7805	gorilla_gorilla	ENSGGOP00000027670	99.2701	98.5401
ENSG00000111405	homo_sapiens	ENSP00000397679	69.5122	59.5122	ornithorhynchus_anatinus	ENSOANP00000035870	86.6261	74.1641
ENSG00000111405	homo_sapiens	ENSP00000397679	84.8781	73.9024	sarcophilus_harrisii	ENSSHAP00000006904	85.9259	74.8148
ENSG00000111405	homo_sapiens	ENSP00000397679	59.7561	51.4634	notamacropus_eugenii	ENSMEUP00000009779	75.6173	65.1235
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	62.9268	choloepus_hoffmanni	ENSCHOP00000009820	73.7127	69.9187
ENSG00000111405	homo_sapiens	ENSP00000397679	85.8537	80.2439	dasypus_novemcinctus	ENSDNOP00000027598	85.8537	80.2439
ENSG00000111405	homo_sapiens	ENSP00000397679	79.0244	73.9024	erinaceus_europaeus	ENSEEUP00000010875	93.1034	87.069
ENSG00000111405	homo_sapiens	ENSP00000397679	76.5854	68.2927	echinops_telfairi	ENSETEP00000002703	89.7143	80
ENSG00000111405	homo_sapiens	ENSP00000397679	84.8781	80.7317	callithrix_jacchus	ENSCJAP00000027379	73.7288	70.1271
ENSG00000111405	homo_sapiens	ENSP00000397679	92.9268	90	callithrix_jacchus	ENSCJAP00000023509	92.9268	90
ENSG00000111405	homo_sapiens	ENSP00000397679	97.8049	96.5854	cercocebus_atys	ENSCATP00000042867	97.5669	96.3504
ENSG00000111405	homo_sapiens	ENSP00000397679	98.2927	96.8293	macaca_fascicularis	ENSMFAP00000000998	98.0535	96.5937
ENSG00000111405	homo_sapiens	ENSP00000397679	98.2927	96.8293	macaca_mulatta	ENSMMUP00000024195	98.0535	96.5937
ENSG00000111405	homo_sapiens	ENSP00000397679	98.2927	96.8293	macaca_nemestrina	ENSMNEP00000030610	98.0535	96.5937
ENSG00000111405	homo_sapiens	ENSP00000397679	98.0488	96.8293	papio_anubis	ENSPANP00000009242	97.8102	96.5937
ENSG00000111405	homo_sapiens	ENSP00000397679	98.0488	96.8293	mandrillus_leucophaeus	ENSMLEP00000036038	97.8102	96.5937
ENSG00000111405	homo_sapiens	ENSP00000397679	70.4878	63.9024	tursiops_truncatus	ENSTTRP00000011930	78.1081	70.8108
ENSG00000111405	homo_sapiens	ENSP00000397679	89.0244	81.7073	vulpes_vulpes	ENSVVUP00000024525	89.9015	82.5123
ENSG00000111405	homo_sapiens	ENSP00000397679	89.2683	81.9512	mus_spretus	MGP_SPRETEiJ_P0041432	88.835	81.5534
ENSG00000111405	homo_sapiens	ENSP00000397679	93.6585	86.0976	equus_asinus	ENSEASP00005051218	92.9782	85.4722
ENSG00000111405	homo_sapiens	ENSP00000397679	73.9024	68.7805	capra_hircus	ENSCHIP00000031430	82.337	76.6304
ENSG00000111405	homo_sapiens	ENSP00000397679	91.4634	85.3659	capra_hircus	ENSCHIP00000018740	90.799	84.7458
ENSG00000111405	homo_sapiens	ENSP00000397679	93.4146	87.3171	loxodonta_africana	ENSLAFP00000006463	92.9612	86.8932
ENSG00000111405	homo_sapiens	ENSP00000397679	93.6585	86.5854	panthera_leo	ENSPLOP00000009749	93.6585	86.5854
ENSG00000111405	homo_sapiens	ENSP00000397679	90.9756	84.1463	ailuropoda_melanoleuca	ENSAMEP00000014302	90.7543	83.9416
ENSG00000111405	homo_sapiens	ENSP00000397679	92.439	86.3415	bos_indicus_hybrid	ENSBIXP00005019414	91.7676	85.7143
ENSG00000111405	homo_sapiens	ENSP00000397679	80.2439	71.4634	oryctolagus_cuniculus	ENSOCUP00000006366	89.1599	79.4038
ENSG00000111405	homo_sapiens	ENSP00000397679	90.2439	83.4146	equus_caballus	ENSECAP00000021628	84.8624	78.4404
ENSG00000111405	homo_sapiens	ENSP00000397679	90.4878	82.9268	canis_lupus_familiaris	ENSCAFP00845036656	89.6135	82.1256
ENSG00000111405	homo_sapiens	ENSP00000397679	93.1707	86.0976	panthera_pardus	ENSPPRP00000011924	93.1707	86.0976
ENSG00000111405	homo_sapiens	ENSP00000397679	92.6829	87.0732	marmota_marmota_marmota	ENSMMMP00000025878	92.9095	87.2861
ENSG00000111405	homo_sapiens	ENSP00000397679	90.9756	83.4146	balaenoptera_musculus	ENSBMSP00010018567	90.3148	82.8087
ENSG00000111405	homo_sapiens	ENSP00000397679	89.0244	82.439	cavia_porcellus	ENSCPOP00000026588	88.8078	82.2384
ENSG00000111405	homo_sapiens	ENSP00000397679	92.9268	85.6098	felis_catus	ENSFCAP00000012976	92.4757	85.1942
ENSG00000111405	homo_sapiens	ENSP00000397679	92.1951	85.1219	ursus_americanus	ENSUAMP00000035623	91.7476	84.7087
ENSG00000111405	homo_sapiens	ENSP00000397679	73.4146	65.6098	monodelphis_domestica	ENSMODP00000012163	91.4894	81.7629
ENSG00000111405	homo_sapiens	ENSP00000397679	86.5854	80.4878	bison_bison_bison	ENSBBBP00000020343	90.5612	84.1837
ENSG00000111405	homo_sapiens	ENSP00000397679	76.0976	69.0244	monodon_monoceros	ENSMMNP00015027552	89.6552	81.3218
ENSG00000111405	homo_sapiens	ENSP00000397679	93.1707	86.0976	sus_scrofa	ENSSSCP00000033431	93.1707	86.0976
ENSG00000111405	homo_sapiens	ENSP00000397679	92.439	84.6341	microcebus_murinus	ENSMICP00000023250	91.3253	83.6145
ENSG00000111405	homo_sapiens	ENSP00000397679	84.3902	77.561	octodon_degus	ENSODEP00000004612	88.7179	81.5385
ENSG00000111405	homo_sapiens	ENSP00000397679	68.0488	61.2195	jaculus_jaculus	ENSJJAP00000017690	86.3777	77.709
ENSG00000111405	homo_sapiens	ENSP00000397679	91.9512	85.1219	ovis_aries_rambouillet	ENSOARP00020003838	91.7275	84.9148
ENSG00000111405	homo_sapiens	ENSP00000397679	88.5366	82.439	ursus_maritimus	ENSUMAP00000000237	92.132	85.7868
ENSG00000111405	homo_sapiens	ENSP00000397679	74.6341	65.3659	ochotona_princeps	ENSOPRP00000001478	86.9318	76.1364
ENSG00000111405	homo_sapiens	ENSP00000397679	77.8049	68.0488	delphinapterus_leucas	ENSDLEP00000008224	66.1826	57.8838
ENSG00000111405	homo_sapiens	ENSP00000397679	87.8049	79.2683	physeter_catodon	ENSPCTP00005018132	88.0196	79.4621
ENSG00000111405	homo_sapiens	ENSP00000397679	89.7561	81.9512	mus_caroli	MGP_CAROLIEiJ_P0039602	89.3204	81.5534
ENSG00000111405	homo_sapiens	ENSP00000397679	80	74.1463	mus_musculus	ENSMUSP00000023105	72.2467	66.9604
ENSG00000111405	homo_sapiens	ENSP00000397679	90.2439	82.6829	dipodomys_ordii	ENSDORP00000017619	90.2439	82.6829
ENSG00000111405	homo_sapiens	ENSP00000397679	92.9268	84.1463	mustela_putorius_furo	ENSMPUP00000000403	92.2518	83.5351
ENSG00000111405	homo_sapiens	ENSP00000397679	96.3415	93.4146	aotus_nancymaae	ENSANAP00000041962	96.1071	93.1873
ENSG00000111405	homo_sapiens	ENSP00000397679	95.8537	92.6829	saimiri_boliviensis_boliviensis	ENSSBOP00000036561	95.6204	92.4574
ENSG00000111405	homo_sapiens	ENSP00000397679	68.7805	63.1707	vicugna_pacos	ENSVPAP00000004613	76.4228	70.1897
ENSG00000111405	homo_sapiens	ENSP00000397679	93.9024	92.6829	chlorocebus_sabaeus	ENSCSAP00000002985	98.4655	97.1867
ENSG00000111405	homo_sapiens	ENSP00000397679	84.1463	79.0244	tupaia_belangeri	ENSTBEP00000014575	94.0054	88.2834
ENSG00000111405	homo_sapiens	ENSP00000397679	89.0244	79.7561	mesocricetus_auratus	ENSMAUP00000013613	88.8078	79.562
ENSG00000111405	homo_sapiens	ENSP00000397679	76.5854	70.4878	phocoena_sinus	ENSPSNP00000023961	90.2299	83.046
ENSG00000111405	homo_sapiens	ENSP00000397679	90.7317	84.1463	camelus_dromedarius	ENSCDRP00005018617	90.5109	83.9416
ENSG00000111405	homo_sapiens	ENSP00000397679	94.3902	88.5366	carlito_syrichta	ENSTSYP00000014324	93.932	88.1068
ENSG00000111405	homo_sapiens	ENSP00000397679	93.4146	86.3415	panthera_tigris_altaica	ENSPTIP00000021885	93.4146	86.3415
ENSG00000111405	homo_sapiens	ENSP00000397679	89.2683	81.7073	rattus_norvegicus	ENSRNOP00000073287	89.0511	81.5085
ENSG00000111405	homo_sapiens	ENSP00000397679	93.1707	86.5854	prolemur_simus	ENSPSMP00000011841	92.0482	85.5422
ENSG00000111405	homo_sapiens	ENSP00000397679	88.7805	81.2195	microtus_ochrogaster	ENSMOCP00000015987	88.5645	81.0219
ENSG00000111405	homo_sapiens	ENSP00000397679	64.3902	57.8049	sorex_araneus	ENSSARP00000001104	70.7775	63.5389
ENSG00000111405	homo_sapiens	ENSP00000397679	89.5122	82.6829	peromyscus_maniculatus_bairdii	ENSPEMP00000000048	89.2944	82.4818
ENSG00000111405	homo_sapiens	ENSP00000397679	92.439	86.3415	bos_mutus	ENSBMUP00000001011	92.2141	86.1314
ENSG00000111405	homo_sapiens	ENSP00000397679	79.7561	73.6585	mus_spicilegus	ENSMSIP00000032436	72.0264	66.5198
ENSG00000111405	homo_sapiens	ENSP00000397679	89.0244	80.9756	cricetulus_griseus_chok1gshd	ENSCGRP00001001614	88.8078	80.7786
ENSG00000111405	homo_sapiens	ENSP00000397679	82.6829	77.561	pteropus_vampyrus	ENSPVAP00000008841	91.6216	85.9459
ENSG00000111405	homo_sapiens	ENSP00000397679	91.7073	83.6585	myotis_lucifugus	ENSMLUP00000010022	91.7073	83.6585
ENSG00000111405	homo_sapiens	ENSP00000397679	85.3659	75.3659	vombatus_ursinus	ENSVURP00010007077	85.1581	75.1825
ENSG00000111405	homo_sapiens	ENSP00000397679	79.2683	72.6829	rhinolophus_ferrumequinum	ENSRFEP00010008260	93.3908	85.6322
ENSG00000111405	homo_sapiens	ENSP00000397679	91.9512	84.3902	neovison_vison	ENSNVIP00000007270	91.2833	83.7772
ENSG00000111405	homo_sapiens	ENSP00000397679	92.6829	86.3415	bos_taurus	ENSBTAP00000043168	92.0097	85.7143
ENSG00000111405	homo_sapiens	ENSP00000397679	89.0244	80.2439	heterocephalus_glaber_female	ENSHGLP00000045253	88.8078	80.0487
ENSG00000111405	homo_sapiens	ENSP00000397679	98.0488	97.0732	rhinopithecus_bieti	ENSRBIP00000003696	97.8102	96.837
ENSG00000111405	homo_sapiens	ENSP00000397679	90.4878	83.1707	canis_lupus_dingo	ENSCAFP00020013660	89.6135	82.3671
ENSG00000111405	homo_sapiens	ENSP00000397679	80.7317	75.8537	sciurus_vulgaris	ENSSVLP00005010497	94.8424	89.1117
ENSG00000111405	homo_sapiens	ENSP00000397679	82.6829	72.9268	phascolarctos_cinereus	ENSPCIP00000005986	86.7008	76.4706
ENSG00000111405	homo_sapiens	ENSP00000397679	63.1707	56.0976	procavia_capensis	ENSPCAP00000001992	70	62.1622
ENSG00000111405	homo_sapiens	ENSP00000397679	89.7561	81.9512	nannospalax_galili	ENSNGAP00000020392	88.8889	81.1594
ENSG00000111405	homo_sapiens	ENSP00000397679	92.439	86.3415	bos_grunniens	ENSBGRP00000036967	91.7676	85.7143
ENSG00000111405	homo_sapiens	ENSP00000397679	87.8049	79.7561	chinchilla_lanigera	ENSCLAP00000002490	87.8049	79.7561
ENSG00000111405	homo_sapiens	ENSP00000397679	92.6829	86.3415	cervus_hanglu_yarkandensis	ENSCHYP00000016118	92.0097	85.7143
ENSG00000111405	homo_sapiens	ENSP00000397679	92.9268	86.3415	catagonus_wagneri	ENSCWAP00000029168	92.9268	86.3415
ENSG00000111405	homo_sapiens	ENSP00000397679	92.9268	87.0732	ictidomys_tridecemlineatus	ENSSTOP00000000858	93.154	87.2861
ENSG00000111405	homo_sapiens	ENSP00000397679	93.6585	85.6098	otolemur_garnettii	ENSOGAP00000004884	92.3077	84.375
ENSG00000111405	homo_sapiens	ENSP00000397679	96.0976	93.4146	cebus_imitator	ENSCCAP00000032215	95.8637	93.1873
ENSG00000111405	homo_sapiens	ENSP00000397679	92.439	85.8537	urocitellus_parryii	ENSUPAP00010004083	92.665	86.0636
ENSG00000111405	homo_sapiens	ENSP00000397679	91.4634	85.3659	moschus_moschiferus	ENSMMSP00000009864	81.3449	75.9219
ENSG00000111405	homo_sapiens	ENSP00000397679	98.0488	97.0732	rhinopithecus_roxellana	ENSRROP00000026636	97.8102	96.837
ENSG00000111405	homo_sapiens	ENSP00000397679	81.2195	74.3902	mus_pahari	MGP_PahariEiJ_P0042954	72.7074	66.5939
ENSG00000111405	homo_sapiens	ENSP00000397679	93.6585	87.3171	propithecus_coquereli	ENSPCOP00000011457	93.4307	87.1046
ENSG00000111405	homo_sapiens	ENSP00000397679	39.2683	24.3902	caenorhabditis_elegans	K02A11.3.1	52.443	32.5733
ENSG00000111405	homo_sapiens	ENSP00000397679	39.7561	25.6098	ciona_intestinalis	ENSCINP00000024013	54.698	35.2349
ENSG00000111405	homo_sapiens	ENSP00000397679	55.3659	37.3171	ciona_intestinalis	ENSCINP00000024012	52.7907	35.5814
ENSG00000111405	homo_sapiens	ENSP00000397679	25.122	19.7561	petromyzon_marinus	ENSPMAP00000003962	83.0645	65.3226
ENSG00000111405	homo_sapiens	ENSP00000397679	55.8537	40	eptatretus_burgeri	ENSEBUP00000023344	54.5238	39.0476
ENSG00000111405	homo_sapiens	ENSP00000397679	47.561	32.6829	callorhinchus_milii	ENSCMIP00000008664	58.5586	40.2402
ENSG00000111405	homo_sapiens	ENSP00000397679	64.8781	47.0732	latimeria_chalumnae	ENSLACP00000015280	67.3418	48.8608
ENSG00000111405	homo_sapiens	ENSP00000397679	41.4634	30.2439	lepisosteus_oculatus	ENSLOCP00000008758	47.619	34.7339
ENSG00000111405	homo_sapiens	ENSP00000397679	66.0976	48.7805	clupea_harengus	ENSCHAP00000008323	63.1702	46.62
ENSG00000111405	homo_sapiens	ENSP00000397679	53.9024	38.0488	danio_rerio	ENSDARP00000064903	72.9373	51.4851
ENSG00000111405	homo_sapiens	ENSP00000397679	58.2927	42.1951	carassius_auratus	ENSCARP00000084745	71.5569	51.7964
ENSG00000111405	homo_sapiens	ENSP00000397679	52.9268	39.7561	carassius_auratus	ENSCARP00000081321	73.5593	55.2542
ENSG00000111405	homo_sapiens	ENSP00000397679	53.6585	40.7317	astyanax_mexicanus	ENSAMXP00000054652	71.8954	54.5752
ENSG00000111405	homo_sapiens	ENSP00000397679	53.6585	40.2439	ictalurus_punctatus	ENSIPUP00000029335	72.8477	54.6358
ENSG00000111405	homo_sapiens	ENSP00000397679	66.0976	49.2683	esox_lucius	ENSELUP00000036252	69.8454	52.0619
ENSG00000111405	homo_sapiens	ENSP00000397679	59.5122	45.122	electrophorus_electricus	ENSEEEP00000021556	69.7143	52.8571
ENSG00000111405	homo_sapiens	ENSP00000397679	67.561	50.2439	oncorhynchus_kisutch	ENSOKIP00005068377	71.2082	52.9563
ENSG00000111405	homo_sapiens	ENSP00000397679	36.3415	24.3902	oncorhynchus_kisutch	ENSOKIP00005004609	51.2027	34.3643
ENSG00000111405	homo_sapiens	ENSP00000397679	67.561	50.2439	oncorhynchus_mykiss	ENSOMYP00000041434	71.2082	52.9563
ENSG00000111405	homo_sapiens	ENSP00000397679	42.1951	30	oncorhynchus_mykiss	ENSOMYP00000030630	61.7857	43.9286
ENSG00000111405	homo_sapiens	ENSP00000397679	47.3171	33.4146	salmo_salar	ENSSSAP00000081186	52.1505	36.828
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	50.2439	salmo_salar	ENSSSAP00000056535	69.5652	52.6854
ENSG00000111405	homo_sapiens	ENSP00000397679	67.3171	50.4878	salmo_trutta	ENSSTUP00000016040	70.9512	53.2134
ENSG00000111405	homo_sapiens	ENSP00000397679	50	36.3415	salmo_trutta	ENSSTUP00000037900	65.2866	47.4522
ENSG00000111405	homo_sapiens	ENSP00000397679	67.3171	49.5122	gadus_morhua	ENSGMOP00000066074	64.9412	47.7647
ENSG00000111405	homo_sapiens	ENSP00000397679	65.8537	49.5122	fundulus_heteroclitus	ENSFHEP00000028974	63.2318	47.541
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	49.2683	poecilia_reticulata	ENSPREP00000024868	70.3412	53.0184
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	49.2683	xiphophorus_maculatus	ENSXMAP00000018504	70.7124	53.2982
ENSG00000111405	homo_sapiens	ENSP00000397679	63.1707	48.7805	oryzias_latipes	ENSORLP00000035139	67.979	52.4934
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	48.2927	cyclopterus_lumpus	ENSCLMP00005020423	69.9229	50.8997
ENSG00000111405	homo_sapiens	ENSP00000397679	65.6098	47.561	oreochromis_niloticus	ENSONIP00000061296	69.8701	50.6493
ENSG00000111405	homo_sapiens	ENSP00000397679	54.6341	40.9756	haplochromis_burtoni	ENSHBUP00000013109	75.6757	56.7568
ENSG00000111405	homo_sapiens	ENSP00000397679	54.3902	40.7317	astatotilapia_calliptera	ENSACLP00000000172	75.0842	56.229
ENSG00000111405	homo_sapiens	ENSP00000397679	64.8781	46.3415	sparus_aurata	ENSSAUP00010001030	66.5	47.5
ENSG00000111405	homo_sapiens	ENSP00000397679	67.0732	48.2927	lates_calcarifer	ENSLCAP00010038271	70.8763	51.0309
ENSG00000111405	homo_sapiens	ENSP00000397679	70.4878	54.1463	xenopus_tropicalis	ENSXETP00000009350	69.1388	53.11
ENSG00000111405	homo_sapiens	ENSP00000397679	65.8537	53.1707	chrysemys_picta_bellii	ENSCPBP00000018745	69.7674	56.3307
ENSG00000111405	homo_sapiens	ENSP00000397679	58.2927	48.7805	sphenodon_punctatus	ENSSPUP00000012830	85.3571	71.4286
ENSG00000111405	homo_sapiens	ENSP00000397679	69.5122	57.0732	crocodylus_porosus	ENSCPRP00005006240	73.6434	60.4651
ENSG00000111405	homo_sapiens	ENSP00000397679	63.6585	51.9512	laticauda_laticaudata	ENSLLTP00000007525	74.5714	60.8571
ENSG00000111405	homo_sapiens	ENSP00000397679	63.6585	51.7073	pseudonaja_textilis	ENSPTXP00000015451	65.9091	53.5354
ENSG00000111405	homo_sapiens	ENSP00000397679	65.6098	51.7073	gallus_gallus	ENSGALP00010034581	74.7222	58.8889
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	52.6829	meleagris_gallopavo	ENSMGAP00000020350	75.5556	60
ENSG00000111405	homo_sapiens	ENSP00000397679	42.9268	28.0488	serinus_canaria	ENSSCAP00000010877	42.615	27.845
ENSG00000111405	homo_sapiens	ENSP00000397679	67.561	55.6098	anolis_carolinensis	ENSACAP00000014640	68.3951	56.2963
ENSG00000111405	homo_sapiens	ENSP00000397679	18.5366	15.8537	anolis_carolinensis	ENSACAP00000032643	89.4118	76.4706
ENSG00000111405	homo_sapiens	ENSP00000397679	52.6829	39.2683	neolamprologus_brichardi	ENSNBRP00000021413	78.2609	58.3333
ENSG00000111405	homo_sapiens	ENSP00000397679	64.6341	52.1951	naja_naja	ENSNNAP00000005260	74.0223	59.7765
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	52.9268	podarcis_muralis	ENSPMRP00000011170	76.4045	60.9551
ENSG00000111405	homo_sapiens	ENSP00000397679	62.1951	48.0488	geospiza_fortis	ENSGFOP00000008941	65.7216	50.7732
ENSG00000111405	homo_sapiens	ENSP00000397679	60.2439	46.8293	taeniopygia_guttata	ENSTGUP00000017740	79.4212	61.7363
ENSG00000111405	homo_sapiens	ENSP00000397679	53.1707	39.2683	erpetoichthys_calabaricus	ENSECRP00000027293	69.8718	51.6026
ENSG00000111405	homo_sapiens	ENSP00000397679	65.8537	46.8293	kryptolebias_marmoratus	ENSKMAP00000025544	69.9482	49.7409
ENSG00000111405	homo_sapiens	ENSP00000397679	65.6098	52.439	salvator_merianae	ENSSMRP00000006312	69.6891	55.6995
ENSG00000111405	homo_sapiens	ENSP00000397679	64.8781	49.2683	oryzias_javanicus	ENSOJAP00000002544	69.8163	53.0184
ENSG00000111405	homo_sapiens	ENSP00000397679	64.1463	46.5854	amphilophus_citrinellus	ENSACIP00000001448	69.0289	50.1312
ENSG00000111405	homo_sapiens	ENSP00000397679	65.6098	47.561	dicentrarchus_labrax	ENSDLAP00005004170	69.1517	50.1285
ENSG00000111405	homo_sapiens	ENSP00000397679	65.1219	48.0488	amphiprion_percula	ENSAPEP00000022150	69.171	51.0363
ENSG00000111405	homo_sapiens	ENSP00000397679	54.6341	42.1951	oryzias_sinensis	ENSOSIP00000007150	73.9274	57.0957
ENSG00000111405	homo_sapiens	ENSP00000397679	69.2683	56.0976	pelodiscus_sinensis	ENSPSIP00000004787	75.1323	60.8466
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	53.1707	gopherus_evgoodei	ENSGEVP00005022597	77.0538	61.7564
ENSG00000111405	homo_sapiens	ENSP00000397679	65.1219	51.7073	chelonoidis_abingdonii	ENSCABP00000029505	77.1676	61.2717
ENSG00000111405	homo_sapiens	ENSP00000397679	66.0976	47.0732	seriola_dumerili	ENSSDUP00000009446	69.8454	49.7423
ENSG00000111405	homo_sapiens	ENSP00000397679	63.9024	46.5854	cottoperca_gobio	ENSCGOP00000010363	67.8756	49.4819
ENSG00000111405	homo_sapiens	ENSP00000397679	68.7805	55.6098	struthio_camelus_australis	ENSSCUP00000011678	78.1163	63.1579
ENSG00000111405	homo_sapiens	ENSP00000397679	67.561	53.9024	anser_brachyrhynchus	ENSABRP00000025618	76.7313	61.2188
ENSG00000111405	homo_sapiens	ENSP00000397679	65.6098	48.7805	gasterosteus_aculeatus	ENSGACP00000000906	69.3299	51.5464
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	45.8537	cynoglossus_semilaevis	ENSCSEP00000005243	70.5263	49.4737
ENSG00000111405	homo_sapiens	ENSP00000397679	65.1219	47.8049	poecilia_formosa	ENSPFOP00000010885	62.8235	46.1176
ENSG00000111405	homo_sapiens	ENSP00000397679	66.5854	49.5122	myripristis_murdjan	ENSMMDP00005049909	70.5426	52.4548
ENSG00000111405	homo_sapiens	ENSP00000397679	60.4878	45.3659	sander_lucioperca	ENSSLUP00000039848	68.8889	51.6667
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	51.9512	strigops_habroptila	ENSSHBP00005011628	70.1571	55.7592
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	48.2927	amphiprion_ocellaris	ENSAOCP00000021987	69.4301	51.2953
ENSG00000111405	homo_sapiens	ENSP00000397679	67.3171	50	hucho_hucho	ENSHHUP00000081201	71.3178	52.9716
ENSG00000111405	homo_sapiens	ENSP00000397679	26.5854	19.0244	hucho_hucho	ENSHHUP00000014699	66.0606	47.2727
ENSG00000111405	homo_sapiens	ENSP00000397679	57.0732	41.7073	betta_splendens	ENSBSLP00000035894	61.7414	45.1187
ENSG00000111405	homo_sapiens	ENSP00000397679	53.4146	42.6829	pygocentrus_nattereri	ENSPNAP00000028910	71.3355	57.0033
ENSG00000111405	homo_sapiens	ENSP00000397679	55.8537	41.9512	anabas_testudineus	ENSATEP00000002184	62.9121	47.2527
ENSG00000111405	homo_sapiens	ENSP00000397679	14.3902	8.53659	ciona_savignyi	ENSCSAVP00000014828	57.2816	33.9806
ENSG00000111405	homo_sapiens	ENSP00000397679	45.6098	30.7317	ciona_savignyi	ENSCSAVP00000014829	57.5385	38.7692
ENSG00000111405	homo_sapiens	ENSP00000397679	66.0976	47.0732	seriola_lalandi_dorsalis	ENSSLDP00000000758	69.8454	49.7423
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	47.561	labrus_bergylta	ENSLBEP00000025915	69.0722	50.2577
ENSG00000111405	homo_sapiens	ENSP00000397679	60.7317	42.9268	pundamilia_nyererei	ENSPNYP00000001659	66.756	47.185
ENSG00000111405	homo_sapiens	ENSP00000397679	61.2195	45.3659	mastacembelus_armatus	ENSMAMP00000003213	66.4021	49.2063
ENSG00000111405	homo_sapiens	ENSP00000397679	65.8537	49.2683	stegastes_partitus	ENSSPAP00000003460	69.9482	52.3316
ENSG00000111405	homo_sapiens	ENSP00000397679	42.439	30.7317	oncorhynchus_tshawytscha	ENSOTSP00005070669	59.3857	43.0034
ENSG00000111405	homo_sapiens	ENSP00000397679	67.3171	50.2439	oncorhynchus_tshawytscha	ENSOTSP00005027113	70.9512	52.9563
ENSG00000111405	homo_sapiens	ENSP00000397679	65.1219	47.561	acanthochromis_polyacanthus	ENSAPOP00000012217	69.171	50.5181
ENSG00000111405	homo_sapiens	ENSP00000397679	68.5366	55.3659	aquila_chrysaetos_chrysaetos	ENSACCP00020012851	75.7412	61.186
ENSG00000111405	homo_sapiens	ENSP00000397679	61.4634	44.878	nothobranchius_furzeri	ENSNFUP00015043604	65.4545	47.7922
ENSG00000111405	homo_sapiens	ENSP00000397679	65.3659	49.0244	cyprinodon_variegatus	ENSCVAP00000000429	62.7635	47.0726
ENSG00000111405	homo_sapiens	ENSP00000397679	53.6585	40	denticeps_clupeoides	ENSDCDP00000016285	73.5786	54.8495
ENSG00000111405	homo_sapiens	ENSP00000397679	44.878	32.1951	larimichthys_crocea	ENSLCRP00005065321	66.426	47.6534
ENSG00000111405	homo_sapiens	ENSP00000397679	66.0976	47.3171	larimichthys_crocea	ENSLCRP00005065319	70.0258	50.1292
ENSG00000111405	homo_sapiens	ENSP00000397679	64.1463	47.561	takifugu_rubripes	ENSTRUP00000034941	67.9587	50.3876
ENSG00000111405	homo_sapiens	ENSP00000397679	34.1463	28.2927	ficedula_albicollis	ENSFALP00000010826	65.7277	54.4601
ENSG00000111405	homo_sapiens	ENSP00000397679	63.9024	47.8049	hippocampus_comes	ENSHCOP00000028410	67.5258	50.5155
ENSG00000111405	homo_sapiens	ENSP00000397679	60.7317	43.6585	cyprinus_carpio_carpio	ENSCCRP00000081021	71.9653	51.7341
ENSG00000111405	homo_sapiens	ENSP00000397679	51.7073	38.2927	cyprinus_carpio_carpio	ENSCCRP00000042361	69.5082	51.4754
ENSG00000111405	homo_sapiens	ENSP00000397679	67.0732	53.4146	coturnix_japonica	ENSCJPP00005025594	68.0693	54.2079
ENSG00000111405	homo_sapiens	ENSP00000397679	66.3415	48.5366	poecilia_latipinna	ENSPLAP00000023045	71.3911	52.231
ENSG00000111405	homo_sapiens	ENSP00000397679	53.4146	39.2683	sinocyclocheilus_grahami	ENSSGRP00000104413	72.5166	53.3113
ENSG00000111405	homo_sapiens	ENSP00000397679	48.2927	35.6098	sinocyclocheilus_grahami	ENSSGRP00000044812	70.7143	52.1429
ENSG00000111405	homo_sapiens	ENSP00000397679	54.6341	40.9756	maylandia_zebra	ENSMZEP00005010899	75.6757	56.7568
ENSG00000111405	homo_sapiens	ENSP00000397679	64.8781	47.8049	tetraodon_nigroviridis	ENSTNIP00000017606	68.3805	50.3856
ENSG00000111405	homo_sapiens	ENSP00000397679	50.9756	36.3415	paramormyrops_kingsleyae	ENSPKIP00000025716	73.0769	52.0979
ENSG00000111405	homo_sapiens	ENSP00000397679	53.9024	39.7561	scleropages_formosus	ENSSFOP00015022577	69.7161	51.4196
ENSG00000111405	homo_sapiens	ENSP00000397679	67.0732	51.9512	leptobrachium_leishanense	ENSLLEP00000007521	57.7731	44.7479
ENSG00000111405	homo_sapiens	ENSP00000397679	66.5854	47.561	scophthalmus_maximus	ENSSMAP00000003969	69.821	49.8721
ENSG00000111405	homo_sapiens	ENSP00000397679	63.9024	49.2683	oryzias_melastigma	ENSOMEP00000007817	68.7664	53.0184

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0004521	enables RNA endonuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005044	enables scavenger receptor activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	TAS	Homo_sapiens(9606)	Component
GO:0005615	located_in extracellular space	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0006508	involved_in proteolysis	1	IDA	Homo_sapiens(9606)	Process
GO:0006897	involved_in endocytosis	1	IEA	Homo_sapiens(9606)	Process
GO:0006955	involved_in immune response	1	IEA	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	IEA	Homo_sapiens(9606)	Process
GO:0007565	involved_in female pregnancy	1	IEP	Homo_sapiens(9606)	Process
GO:0008083	enables growth factor activity	1	NAS	Homo_sapiens(9606)	Function
GO:0008236	NOT enables serine-type peptidase activity	2	IDA	Homo_sapiens(9606)	Function
GO:0016829	enables lyase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0030145	enables manganese ion binding	1	TAS	Homo_sapiens(9606)	Function
GO:0030247	enables polysaccharide binding	1	IEA	Homo_sapiens(9606)	Function