Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000110713 Gene ID 4928 Accession 8068
Symbol NUP98 Alias ADIR2;NUP96;NUP196;Nup98-96 Full Name nucleoporin 98 and 96 precursor
Status Confidence Length 126710 bases Strand Minus strand
Position 11 : 3671083 - 3797792 RNA binding domain N.A.
Summary Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. [provided by RefSeq, Feb 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35258330 Nup98 Is Subverted from Annulate Lamellae by Hepatitis C Virus Core Protein to Foster Viral Assembly. Bertrand Boson 2022-04-26 mBio
28221134 Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. S Juliana Capitanio 2017-02-21 eLife
32295268 Classic and Variants APLs, as Viewed from a Therapy Response. Marie-Claude Geoffroy 2020-04-14 Cancers
33479542 Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression. Stefan Terlecki-Zaniewicz 2021-02-01 Nature structural & molecular biology
32511329 A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. E David Gordon 2020-03-22 bioRxiv : the preprint server for biology
37325571 Advances in molecular characterization of pediatric acute megakaryoblastic leukemia not associated with Down syndrome; impact on therapy development. Jixia Li 2023-01-01 Frontiers in cell and developmental biology
10087256 A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96. M B Fontoura 1999-03-22 The Journal of cell biology
26740045 Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes. Masahiro Oka 2016-01-07 eLife
31709264 RARG Gene Dysregulation in Acute Myeloid Leukemia. Rosa Maria Conserva 2019-01-01 Frontiers in molecular biosciences
33033226 Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Han Feng 2020-10-27 Proceedings of the National Academy of Sciences of the United States of America
29269482 Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells. M Tobias Franks 2017-11-15 Genes & development
32664447 Disclosing the Interactome of Leukemogenic NUP98-HOXA9 and SET-NUP214 Fusion Proteins Using a Proteomic Approach. Adélia Mendes 2020-07-10 Cells
33322130 The Role of Nucleoporin Elys in Nuclear Pore Complex Assembly and Regulation of Genome Architecture. Y Yuri Shevelyov 2020-12-13 International journal of molecular sciences
25184662 Regulation of mRNA trafficking by nuclear pore complexes. Amandine Bonnet 2014-09-02 Genes
20498086 Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Yi Ren 2010-06-08 Proceedings of the National Academy of Sciences of the United States of America

Transcripts

Name Transcript ID bp Protein Translation ID
NUP98-220 ENST00000533346 580 93aa ENSP00000432275
NUP98-203 ENST00000359171 7023 1817aa ENSP00000352091
NUP98-201 ENST00000324932 6726 1800aa ENSP00000316032
NUP98-216 ENST00000529379 6585 1753aa ENSP00000432142
NUP98-222 ENST00000700595 4318 1062aa ENSP00000515086
NUP98-223 ENST00000700596 5567 No protein -
NUP98-224 ENST00000700597 6641 1791aa ENSP00000515087
NUP98-225 ENST00000700598 6658 1783aa ENSP00000515088
NUP98-214 ENST00000527104 6691 1792aa ENSP00000436226
NUP98-202 ENST00000355260 6731 1726aa ENSP00000347404
NUP98-226 ENST00000700599 2899 No protein -
NUP98-227 ENST00000700600 2629 500aa ENSP00000515089
NUP98-215 ENST00000529063 6491 1182aa ENSP00000433226
NUP98-221 ENST00000650171 6837 1348aa ENSP00000497709
NUP98-228 ENST00000700601 6519 1644aa ENSP00000515090
NUP98-209 ENST00000469881 2920 No protein -
NUP98-229 ENST00000700602 6506 1661aa ENSP00000515091
NUP98-207 ENST00000429801 2541 753aa ENSP00000413146
NUP98-230 ENST00000700603 5801 1753aa ENSP00000515092
NUP98-210 ENST00000482690 310 No protein -
NUP98-213 ENST00000524563 841 232aa ENSP00000433515
NUP98-217 ENST00000530345 436 No protein -
NUP98-212 ENST00000488828 712 No protein -
NUP98-211 ENST00000483285 4352 No protein -
NUP98-205 ENST00000397007 3987 937aa ENSP00000380202
NUP98-204 ENST00000397004 3943 920aa ENSP00000380199
NUP98-231 ENST00000700604 2892 No protein -
NUP98-232 ENST00000700605 3595 875aa ENSP00000515093
NUP98-233 ENST00000700606 3846 920aa ENSP00000515094
NUP98-234 ENST00000700607 3788 912aa ENSP00000515095
NUP98-235 ENST00000700608 3694 913aa ENSP00000515096
NUP98-218 ENST00000530516 391 No protein -
NUP98-206 ENST00000397013 939 136aa ENSP00000380208
NUP98-236 ENST00000700609 2233 436aa ENSP00000515097
NUP98-208 ENST00000461047 545 No protein -
NUP98-219 ENST00000532475 553 124aa ENSP00000434698

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
20539Bilirubin1.205e-005-
20566Bilirubin1.205e-005-
20635Bilirubin1.205e-005-
20674Bilirubin1.205e-005-
6882613,16,19-docosatrienoic acid7E-623934736

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000110713

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000110713homo_sapiensENSP0000031603281.777881.5556nomascus_leucogenysENSNLEP0000003524497.937597.6713
ENSG00000110713homo_sapiensENSP0000031603298.944498.6111pan_paniscusENSPPAP0000002492098.561198.2291
ENSG00000110713homo_sapiensENSP0000031603298.944498.4444pongo_abeliiENSPPYP0000003756098.018797.5234
ENSG00000110713homo_sapiensENSP0000031603299.722299.3889pan_troglodytesENSPTRP0000008745999.722299.3889
ENSG00000110713homo_sapiensENSP0000031603299.777899.7222gorilla_gorillaENSGGOP0000002748198.844298.7892
ENSG00000110713homo_sapiensENSP000003160328981.6667ornithorhynchus_anatinusENSOANP0000000820184.138777.2059
ENSG00000110713homo_sapiensENSP0000031603291.555684.3889sarcophilus_harrisiiENSSHAP0000004594691.606484.4358
ENSG00000110713homo_sapiensENSP0000031603269.388964.1667notamacropus_eugeniiENSMEUP0000000939669.582264.3454
ENSG00000110713homo_sapiensENSP0000031603266.722264.1667choloepus_hoffmanniENSCHOP0000000318367.700165.1071
ENSG00000110713homo_sapiensENSP0000031603291.888988dasypus_novemcinctusENSDNOP0000000208991.685187.8049
ENSG00000110713homo_sapiensENSP0000031603263.277860.7222erinaceus_europaeusENSEEUP0000001271468.531965.7641
ENSG00000110713homo_sapiensENSP0000031603264.222262echinops_telfairiENSETEP0000001206664.222262
ENSG00000110713homo_sapiensENSP0000031603298.166796.8333callithrix_jacchusENSCJAP0000002839497.301895.9802
ENSG00000110713homo_sapiensENSP0000031603225.524.7778callithrix_jacchusENSCJAP0000006046891.98489.3788
ENSG00000110713homo_sapiensENSP0000031603298.722298.2222cercocebus_atysENSCATP0000001968197.798697.3032
ENSG00000110713homo_sapiensENSP0000031603298.944498.4444macaca_fascicularisENSMFAP0000002753795.342694.8608
ENSG00000110713homo_sapiensENSP0000031603298.777898.2222macaca_mulattaENSMMUP0000005769694.776194.2431
ENSG00000110713homo_sapiensENSP0000031603293.555692.5macaca_nemestrinaENSMNEP0000001085696.063994.98
ENSG00000110713homo_sapiensENSP0000031603298.833398.1667papio_anubisENSPANP0000003807897.908697.2482
ENSG00000110713homo_sapiensENSP0000031603295.611194.6667mandrillus_leucophaeusENSMLEP0000003913997.451996.4892
ENSG00000110713homo_sapiensENSP0000031603285.055682.3889tursiops_truncatusENSTTRP0000001577985.3482.6644
ENSG00000110713homo_sapiensENSP0000031603296.444493.0556vulpes_vulpesENSVVUP0000003570396.444493.0556
ENSG00000110713homo_sapiensENSP0000031603262.888960.6667mus_spretusMGP_SPRETEiJ_P008446395.366591.9966
ENSG00000110713homo_sapiensENSP0000031603297.444494.3889equus_asinusENSEASP0000500082996.532793.5058
ENSG00000110713homo_sapiensENSP0000031603296.593.0556capra_hircusENSCHIP0000001611895.649892.2357
ENSG00000110713homo_sapiensENSP0000031603265.166761.9444loxodonta_africanaENSLAFP0000001093195.833391.0948
ENSG00000110713homo_sapiensENSP0000031603296.777893.3333panthera_leoENSPLOP0000001916995.925192.511
ENSG00000110713homo_sapiensENSP0000031603296.555693.3889ailuropoda_melanoleucaENSAMEP0000001155295.652292.5151
ENSG00000110713homo_sapiensENSP0000031603296.611193.6111bos_indicus_hybridENSBIXP0000502150095.759992.7863
ENSG00000110713homo_sapiensENSP0000031603296.222293.0556oryctolagus_cuniculusENSOCUP0000004408394.904191.7808
ENSG00000110713homo_sapiensENSP0000031603297.444494.5equus_caballusENSECAP0000001346896.532793.6159
ENSG00000110713homo_sapiensENSP0000031603296.555693.1667canis_lupus_familiarisENSCAFP0084501582295.652292.295
ENSG00000110713homo_sapiensENSP0000031603296.777893.3333panthera_pardusENSPPRP0000002430495.925192.511
ENSG00000110713homo_sapiensENSP0000031603296.944493.5556marmota_marmota_marmotaENSMMMP0000001402696.037492.6802
ENSG00000110713homo_sapiensENSP0000031603296.593.4444balaenoptera_musculusENSBMSP0001002809795.597192.5702
ENSG00000110713homo_sapiensENSP0000031603291.833387.5cavia_porcellusENSCPOP0000000585692.65788.2848
ENSG00000110713homo_sapiensENSP0000031603296.777893.3889felis_catusENSFCAP0000003091095.925192.5661
ENSG00000110713homo_sapiensENSP0000031603259.166756ursus_americanusENSUAMP0000003602692.048487.1219
ENSG00000110713homo_sapiensENSP0000031603225.888925.3889ursus_americanusENSUAMP0000002041995.10293.2653
ENSG00000110713homo_sapiensENSP0000031603291.666784.6111monodelphis_domesticaENSMODP0000001030590.85983.8656
ENSG00000110713homo_sapiensENSP0000031603296.555693.5bison_bison_bisonENSBBBP0000000409195.704892.6762
ENSG00000110713homo_sapiensENSP0000031603296.666793.5monodon_monocerosENSMMNP0001502645395.762292.6252
ENSG00000110713homo_sapiensENSP0000031603291.833387.9444sus_scrofaENSSSCP0000001571394.295590.3023
ENSG00000110713homo_sapiensENSP0000031603297.222294.3889microcebus_murinusENSMICP0000003876296.312693.5058
ENSG00000110713homo_sapiensENSP0000031603293.666789.1111octodon_degusENSODEP0000001182592.892688.3747
ENSG00000110713homo_sapiensENSP0000031603294.833391.1111jaculus_jaculusENSJJAP0000001844893.997890.3084
ENSG00000110713homo_sapiensENSP0000031603296.593.0556ovis_aries_rambouilletENSOARP0002001638695.649892.2357
ENSG00000110713homo_sapiensENSP0000031603296.444493.2222ursus_maritimusENSUMAP0000000888495.542192.35
ENSG00000110713homo_sapiensENSP0000031603266.222262.9444ochotona_princepsENSOPRP0000000944466.25962.9794
ENSG00000110713homo_sapiensENSP0000031603296.833393.6111delphinapterus_leucasENSDLEP0000001072195.506992.3288
ENSG00000110713homo_sapiensENSP000003160322119.7222physeter_catodonENSPCTP0000502847290.865485.3365
ENSG00000110713homo_sapiensENSP0000031603250.222249.0556physeter_catodonENSPCTP0000502835796.581294.3376
ENSG00000110713homo_sapiensENSP0000031603262.944460.6111mus_caroliMGP_CAROLIEiJ_P008109795.450791.9124
ENSG00000110713homo_sapiensENSP0000031603295.591.5556mus_musculusENSMUSP0000014811594.658690.7489
ENSG00000110713homo_sapiensENSP0000031603296.277892.4444dipodomys_ordiiENSDORP0000001466895.429591.63
ENSG00000110713homo_sapiensENSP0000031603296.333393.1111mustela_putorius_furoENSMPUP0000001034696.279893.0594
ENSG00000110713homo_sapiensENSP0000031603298.333396.7778aotus_nancymaaeENSANAP0000000607297.46795.9251
ENSG00000110713homo_sapiensENSP0000031603296.222294.6667saimiri_boliviensis_boliviensisENSSBOP0000002836696.597995.0363
ENSG00000110713homo_sapiensENSP0000031603291.833388.7778vicugna_pacosENSVPAP0000000492692.294889.2239
ENSG00000110713homo_sapiensENSP0000031603298.888998.3333chlorocebus_sabaeusENSCSAP0000000059098.888998.3333
ENSG00000110713homo_sapiensENSP0000031603281.578.2778tupaia_belangeriENSTBEP0000000394082.694579.425
ENSG00000110713homo_sapiensENSP0000031603291.444487.7778mesocricetus_auratusENSMAUP0000000582794.489190.7003
ENSG00000110713homo_sapiensENSP0000031603296.666793.6111phocoena_sinusENSPSNP0000000998096.666793.6111
ENSG00000110713homo_sapiensENSP0000031603296.833393.7222camelus_dromedariusENSCDRP0000500259495.980292.8965
ENSG00000110713homo_sapiensENSP0000031603283.722281.2778carlito_syrichtaENSTSYP0000000808296.664593.8422
ENSG00000110713homo_sapiensENSP0000031603244.222243.2222panthera_tigris_altaicaENSPTIP0000001783099.624597.3717
ENSG00000110713homo_sapiensENSP0000031603221.333319.8889panthera_tigris_altaicaENSPTIP0000001600192.307786.0577
ENSG00000110713homo_sapiensENSP0000031603295.611191.3333rattus_norvegicusENSRNOP0000002757594.768790.5286
ENSG00000110713homo_sapiensENSP0000031603297.222294.5556prolemur_simusENSPSMP0000001950096.312693.6709
ENSG00000110713homo_sapiensENSP0000031603295.722291.7778microtus_ochrogasterENSMOCP0000000836894.878990.9692
ENSG00000110713homo_sapiensENSP000003160328581.0556sorex_araneusENSSARP0000000848385.094681.1457
ENSG00000110713homo_sapiensENSP0000031603295.777891.3889peromyscus_maniculatus_bairdiiENSPEMP0000001739994.933990.5837
ENSG00000110713homo_sapiensENSP0000031603296.611193.6111bos_mutusENSBMUP0000000004196.664893.6631
ENSG00000110713homo_sapiensENSP0000031603295.591.5mus_spicilegusENSMSIP0000000339994.658690.6938
ENSG00000110713homo_sapiensENSP0000031603295.666791.6667cricetulus_griseus_chok1gshdENSCGRP0000102202295.719891.7176
ENSG00000110713homo_sapiensENSP0000031603296.777893.2778pteropus_vampyrusENSPVAP0000001551396.885493.3815
ENSG00000110713homo_sapiensENSP0000031603295.591.9444myotis_lucifugusENSMLUP0000001238295.44791.8934
ENSG00000110713homo_sapiensENSP000003160329184.3333vombatus_ursinusENSVURP0001002902491.151984.4741
ENSG00000110713homo_sapiensENSP0000031603296.593.2778rhinolophus_ferrumequinumENSRFEP0001002354295.597192.4051
ENSG00000110713homo_sapiensENSP0000031603294.388991neovison_visonENSNVIP0000002518495.342391.9192
ENSG00000110713homo_sapiensENSP0000031603296.611193.6111bos_taurusENSBTAP0000001109295.759992.7863
ENSG00000110713homo_sapiensENSP0000031603293.666789.3889heterocephalus_glaber_femaleENSHGLP0000001470792.943888.699
ENSG00000110713homo_sapiensENSP0000031603298.611198.1111rhinopithecus_bietiENSRBIP0000003732998.665998.1656
ENSG00000110713homo_sapiensENSP0000031603296.555693.1111canis_lupus_dingoENSCAFP0002001041195.652292.24
ENSG00000110713homo_sapiensENSP0000031603296.611193.3333sciurus_vulgarisENSSVLP0000501570695.759992.511
ENSG00000110713homo_sapiensENSP0000031603288.944482.5phascolarctos_cinereusENSPCIP0000002895591.017684.423
ENSG00000110713homo_sapiensENSP0000031603274.571.1667procavia_capensisENSPCAP0000000503382.37178.6855
ENSG00000110713homo_sapiensENSP0000031603249.722248.3889nannospalax_galiliENSNGAP0000000846095.619793.0556
ENSG00000110713homo_sapiensENSP0000031603296.444493.4444bos_grunniensENSBGRP0000001732195.594792.6211
ENSG00000110713homo_sapiensENSP0000031603293.589.5556chinchilla_lanigeraENSCLAP0000002393492.727388.8154
ENSG00000110713homo_sapiensENSP0000031603296.555693.4444cervus_hanglu_yarkandensisENSCHYP0000000042795.704892.6211
ENSG00000110713homo_sapiensENSP0000031603296.111192.8333catagonus_wagneriENSCWAP0000000050095.264392.0154
ENSG00000110713homo_sapiensENSP0000031603296.944493.5556ictidomys_tridecemlineatusENSSTOP0000002726796.090392.7313
ENSG00000110713homo_sapiensENSP0000031603262.555660.3333otolemur_garnettiiENSOGAP0000001564994.94191.5683
ENSG00000110713homo_sapiensENSP0000031603298.444497.0556cebus_imitatorENSCCAP0000000868898.499297.1095
ENSG00000110713homo_sapiensENSP0000031603296.888993.5556urocitellus_parryiiENSUPAP0001002439396.942793.6076
ENSG00000110713homo_sapiensENSP0000031603296.611193.5556moschus_moschiferusENSMMSP0000002237995.812792.7824
ENSG00000110713homo_sapiensENSP0000031603298.611198rhinopithecus_roxellanaENSRROP0000001527898.665998.0545
ENSG00000110713homo_sapiensENSP0000031603262.944460.7222mus_pahariMGP_PahariEiJ_P001793095.450792.0809
ENSG00000110713homo_sapiensENSP0000031603292.611190.1111propithecus_coquereliENSPCOP0000001794296.247193.649
ENSG00000110713homo_sapiensENSP0000031603242.527.5caenorhabditis_elegansZK328.5b.145.5929.4994
ENSG00000110713homo_sapiensENSP0000031603250.944435.0556drosophila_melanogasterFBpp008385146.785732.1939
ENSG00000110713homo_sapiensENSP0000031603215.333312.0556ciona_intestinalisENSCINP0000000102856.790144.6502
ENSG00000110713homo_sapiensENSP0000031603263.277848.7222petromyzon_marinusENSPMAP0000000233560.488646.5746
ENSG00000110713homo_sapiensENSP0000031603226.833319.8889eptatretus_burgeriENSEBUP0000000261554.026840.0447
ENSG00000110713homo_sapiensENSP0000031603258.555644.2222eptatretus_burgeriENSEBUP0000002581758.915644.4941
ENSG00000110713homo_sapiensENSP0000031603272.833359.3333callorhinchus_miliiENSCMIP0000003098174.53160.7163
ENSG00000110713homo_sapiensENSP0000031603270.558.2222latimeria_chalumnaeENSLACP0000000301170.893958.5475
ENSG00000110713homo_sapiensENSP0000031603219.166716.2778lepisosteus_oculatusENSLOCP0000000055679.861167.8241
ENSG00000110713homo_sapiensENSP0000031603216.222213.6667lepisosteus_oculatusENSLOCP0000000075579.347866.8478
ENSG00000110713homo_sapiensENSP0000031603270.277857.3889clupea_harengusENSCHAP0000001396570.630957.6773
ENSG00000110713homo_sapiensENSP0000031603274.333361.7222danio_rerioENSDARP0000011041373.759661.2459
ENSG00000110713homo_sapiensENSP0000031603214.888913carassius_auratusENSCARP0000010166281.45971.1246
ENSG00000110713homo_sapiensENSP000003160327460.9444astyanax_mexicanusENSAMXP0000003256273.835960.8093
ENSG00000110713homo_sapiensENSP0000031603272.888961.2778ictalurus_punctatusENSIPUP0000001326372.646761.0742
ENSG00000110713homo_sapiensENSP0000031603273.444460.5esox_luciusENSELUP0000000450572.043659.3461
ENSG00000110713homo_sapiensENSP0000031603273.777861.2222electrophorus_electricusENSEEEP0000004096673.329760.8504
ENSG00000110713homo_sapiensENSP0000031603272.388959.6667oncorhynchus_kisutchENSOKIP0000506147072.108559.4355
ENSG00000110713homo_sapiensENSP0000031603273.555660.8889oncorhynchus_kisutchENSOKIP0000509428171.722659.3716
ENSG00000110713homo_sapiensENSP0000031603272.444459.6111oncorhynchus_mykissENSOMYP0000005990572.044259.2818
ENSG00000110713homo_sapiensENSP0000031603273.833361oncorhynchus_mykissENSOMYP0000006813472.702460.0656
ENSG00000110713homo_sapiensENSP0000031603273.555661salmo_salarENSSSAP0000011437172.468560.0985
ENSG00000110713homo_sapiensENSP0000031603273.055660.0556salmo_salarENSSSAP0000008885872.611859.6908
ENSG00000110713homo_sapiensENSP0000031603272.777860.1111salmo_truttaENSSTUP0000004478972.335759.746
ENSG00000110713homo_sapiensENSP0000031603273.611161salmo_truttaENSSTUP0000007260072.523360.0985
ENSG00000110713homo_sapiensENSP000003160327359.4444gadus_morhuaENSGMOP0000003285969.671356.7338
ENSG00000110713homo_sapiensENSP0000031603219.555615.6111fundulus_heteroclitusENSFHEP0000002718468.884554.9902
ENSG00000110713homo_sapiensENSP0000031603272.611159.8889poecilia_reticulataENSPREP0000000301271.813259.2308
ENSG00000110713homo_sapiensENSP0000031603275.22222xiphophorus_maculatusENSXMAP0000002355059.715644.5498
ENSG00000110713homo_sapiensENSP0000031603214.833311.7778xiphophorus_maculatusENSXMAP0000003202971.390456.6845
ENSG00000110713homo_sapiensENSP0000031603215.222213.2778xiphophorus_maculatusENSXMAP0000000679277.840967.8977
ENSG00000110713homo_sapiensENSP0000031603272.722259.5556oryzias_latipesENSORLP0000003911171.923158.9011
ENSG00000110713homo_sapiensENSP000003160327157.7222cyclopterus_lumpusENSCLMP0000501629870.45257.2767
ENSG00000110713homo_sapiensENSP000003160327.333335.66667haplochromis_burtoniENSHBUP0000001609968.393852.8497
ENSG00000110713homo_sapiensENSP0000031603221.444418.2778haplochromis_burtoniENSHBUP0000001604876.435665.1485
ENSG00000110713homo_sapiensENSP0000031603233.444428.5astatotilapia_callipteraENSACLP0000004018176.687965.3503
ENSG00000110713homo_sapiensENSP0000031603217.888913.7778astatotilapia_callipteraENSACLP0000004012576.484658.9074
ENSG00000110713homo_sapiensENSP0000031603273.833360.3889astatotilapia_callipteraENSACLP0000004031372.702459.4639
ENSG00000110713homo_sapiensENSP0000031603274.277861.2778sparus_aurataENSSAUP0001001925172.821460.0763
ENSG00000110713homo_sapiensENSP0000031603274.611161.3889lates_calcariferENSLCAP0001004737373.347960.3495
ENSG00000110713homo_sapiensENSP0000031603240.277831.3333lates_calcariferENSLCAP0001003339468.720453.4597
ENSG00000110713homo_sapiensENSP0000031603277.777864.3889xenopus_tropicalisENSXETP0000006464478.25664.7848
ENSG00000110713homo_sapiensENSP0000031603287.722280.1667chrysemys_picta_belliiENSCPBP0000000398087.624980.0777
ENSG00000110713homo_sapiensENSP0000031603284.722276.5556sphenodon_punctatusENSSPUP0000002394586.549478.2066
ENSG00000110713homo_sapiensENSP0000031603273.055665.1667crocodylus_porosusENSCPRP0000502499984.240975.1441
ENSG00000110713homo_sapiensENSP000003160328372.6667laticauda_laticaudataENSLLTP0000001165883.046172.7071
ENSG00000110713homo_sapiensENSP000003160325953.0556pseudonaja_textilisENSPTXP0000001660081.254873.0681
ENSG00000110713homo_sapiensENSP0000031603272.055663.7778anas_platyrhynchos_platyrhynchosENSAPLP0000001194785.723775.8757
ENSG00000110713homo_sapiensENSP0000031603286.388976.7222gallus_gallusENSGALP0001000439785.722276.1301
ENSG00000110713homo_sapiensENSP0000031603282.111172.5meleagris_gallopavoENSMGAP0000002875683.786873.9796
ENSG00000110713homo_sapiensENSP0000031603215.666714.2222serinus_canariaENSSCAP0000002354388.401380.2508
ENSG00000110713homo_sapiensENSP0000031603270.833361.2778serinus_canariaENSSCAP0000001187480.849769.9429
ENSG00000110713homo_sapiensENSP0000031603282.611172.4444parus_majorENSPMJP0000000640385.361774.8565
ENSG00000110713homo_sapiensENSP0000031603269.888961.1111anolis_carolinensisENSACAP0000004049077.894768.1115
ENSG00000110713homo_sapiensENSP0000031603220.388917.3333neolamprologus_brichardiENSNBRP0000002210574.89863.6735
ENSG00000110713homo_sapiensENSP000003160327.166675.5neolamprologus_brichardiENSNBRP0000002212667.539351.8325
ENSG00000110713homo_sapiensENSP0000031603256.222248.5naja_najaENSNNAP0000001832479.559768.6321
ENSG00000110713homo_sapiensENSP0000031603280.444470.9444podarcis_muralisENSPMRP0000000999584.137174.201
ENSG00000110713homo_sapiensENSP0000031603280.666771.0556geospiza_fortisENSGFOP0000001010281.435871.733
ENSG00000110713homo_sapiensENSP0000031603286.277876.0556taeniopygia_guttataENSTGUP0000000057586.518176.2674
ENSG00000110713homo_sapiensENSP0000031603271.166758.1111erpetoichthys_calabaricusENSECRP0000000693374.003560.4275
ENSG00000110713homo_sapiensENSP0000031603273.560.3333kryptolebias_marmoratusENSKMAP0000001155373.053659.9669
ENSG00000110713homo_sapiensENSP0000031603284.833375salvator_merianaeENSSMRP0000000191684.739274.9168
ENSG00000110713homo_sapiensENSP0000031603272.055659.3333oryzias_javanicusENSOJAP0000002478971.224658.6491
ENSG00000110713homo_sapiensENSP0000031603260.549amphilophus_citrinellusENSACIP0000001743071.037257.5342
ENSG00000110713homo_sapiensENSP0000031603274.444461.5dicentrarchus_labraxENSDLAP0000506767372.120659.5802
ENSG00000110713homo_sapiensENSP0000031603262.777851.9444amphiprion_perculaENSAPEP0000000832271.51959.1772
ENSG00000110713homo_sapiensENSP0000031603288.055680.1667pelodiscus_sinensisENSPSIP0000001911488.006780.1222
ENSG00000110713homo_sapiensENSP0000031603287.580.0556gopherus_evgoodeiENSGEVP0000500097587.402979.9667
ENSG00000110713homo_sapiensENSP0000031603287.277879.5chelonoidis_abingdoniiENSCABP0000002395287.180979.4118
ENSG00000110713homo_sapiensENSP0000031603271.777858.2222seriola_dumeriliENSSDUP0000000901472.178858.5475
ENSG00000110713homo_sapiensENSP0000031603273.333360.2778cottoperca_gobioENSCGOP0000000527471.739158.9674
ENSG00000110713homo_sapiensENSP0000031603288.055678.9444struthio_camelus_australisENSSCUP0000000541788.153579.0323
ENSG00000110713homo_sapiensENSP0000031603287.166777.8889anser_brachyrhynchusENSABRP0000001364787.263677.9755
ENSG00000110713homo_sapiensENSP0000031603267.777855.2778gasterosteus_aculeatusENSGACP0000000253371.13758.0175
ENSG00000110713homo_sapiensENSP0000031603271.833358.2222cynoglossus_semilaevisENSCSEP0000001016170.348257.0185
ENSG00000110713homo_sapiensENSP0000031603273.166760.5poecilia_formosaENSPFOP0000000040672.362659.8352
ENSG00000110713homo_sapiensENSP0000031603274.111160.9444myripristis_murdjanENSMMDP0000503084172.264459.4258
ENSG00000110713homo_sapiensENSP0000031603271.558.6667sander_luciopercaENSSLUP0000001946972.959259.8639
ENSG00000110713homo_sapiensENSP0000031603286.833377.3889strigops_habroptilaENSSHBP0000502119786.401377.0039
ENSG00000110713homo_sapiensENSP0000031603274.555662.0556amphiprion_ocellarisENSAOCP0000002861973.053960.8057
ENSG00000110713homo_sapiensENSP000003160328072.5terrapene_carolina_triunguisENSTMTP0000000904084.358576.4499
ENSG00000110713homo_sapiensENSP0000031603273.333360.3333hucho_huchoENSHHUP0000004856073.251960.2664
ENSG00000110713homo_sapiensENSP0000031603273.388960.7222hucho_huchoENSHHUP0000002665372.542660.022
ENSG00000110713homo_sapiensENSP0000031603273.166759.7778betta_splendensENSBSLP0000001295972.04658.8621
ENSG00000110713homo_sapiensENSP0000031603273.611161.6111pygocentrus_nattereriENSPNAP0000002809473.898561.8516
ENSG00000110713homo_sapiensENSP0000031603275.666762.0556anabas_testudineusENSATEP0000001612974.021760.7065
ENSG00000110713homo_sapiensENSP0000031603222.111116.7778ciona_savignyiENSCSAVP0000000787955.898942.4157
ENSG00000110713homo_sapiensENSP0000031603220.333314.0556saccharomyces_cerevisiaeYMR047C32.884122.7314
ENSG00000110713homo_sapiensENSP0000031603220.513.7222saccharomyces_cerevisiaeYKL068W38.477625.756
ENSG00000110713homo_sapiensENSP0000031603271.222257.8889seriola_lalandi_dorsalisENSSLDP0000001686972.225358.7042
ENSG00000110713homo_sapiensENSP0000031603273.611159.7778labrus_bergyltaENSLBEP0000000145471.467158.0367
ENSG00000110713homo_sapiensENSP0000031603214.444411.7778pundamilia_nyerereiENSPNYP0000000228973.863660.2273
ENSG00000110713homo_sapiensENSP0000031603223.777818.6667pundamilia_nyerereiENSPNYP0000003160167.614553.0806
ENSG00000110713homo_sapiensENSP000003160327.277785.61111pundamilia_nyerereiENSPNYP0000003159968.586452.8796
ENSG00000110713homo_sapiensENSP0000031603275.166761.1667mastacembelus_armatusENSMAMP0000003345073.974860.1968
ENSG00000110713homo_sapiensENSP0000031603274.944462.0556stegastes_partitusENSSPAP0000001894773.355160.7395
ENSG00000110713homo_sapiensENSP0000031603273.888961oncorhynchus_tshawytschaENSOTSP0000506552272.836860.1314
ENSG00000110713homo_sapiensENSP0000031603272.611159.8889oncorhynchus_tshawytschaENSOTSP0000506159272.4159.723
ENSG00000110713homo_sapiensENSP0000031603217.111113.1667acanthochromis_polyacanthusENSAPOP0000000658977.19359.3985
ENSG00000110713homo_sapiensENSP0000031603215.833313.8889acanthochromis_polyacanthusENSAPOP0000002539281.196671.2251
ENSG00000110713homo_sapiensENSP0000031603287.722278.7778aquila_chrysaetos_chrysaetosENSACCP0002001501087.868778.9093
ENSG00000110713homo_sapiensENSP0000031603271.666757.7778nothobranchius_furzeriENSNFUP0001501113070.762557.0488
ENSG00000110713homo_sapiensENSP0000031603273.444459.7778cyprinodon_variegatusENSCVAP0000002888473.038759.4475
ENSG00000110713homo_sapiensENSP0000031603271.277858.5556denticeps_clupeoidesENSDCDP0000001431571.159258.4581
ENSG00000110713homo_sapiensENSP0000031603274.561.1667larimichthys_croceaENSLCRP0000501732072.682959.6748
ENSG00000110713homo_sapiensENSP0000031603272.944459.7222takifugu_rubripesENSTRUP0000006382971.905858.8719
ENSG00000110713homo_sapiensENSP0000031603254.277848.0556ficedula_albicollisENSFALP0000001063884.956575.2174
ENSG00000110713homo_sapiensENSP0000031603217.666714.2222ficedula_albicollisENSFALP0000002180951.043341.0915
ENSG00000110713homo_sapiensENSP0000031603215.277813.2778hippocampus_comesENSHCOP0000000699477.030866.9468
ENSG00000110713homo_sapiensENSP0000031603215.166711.8333hippocampus_comesENSHCOP0000002175166.748252.0782
ENSG00000110713homo_sapiensENSP0000031603210.11117.88889hippocampus_comesENSHCOP0000000698162.328848.6301
ENSG00000110713homo_sapiensENSP0000031603274.444462.2222cyprinus_carpio_carpioENSCCRP0000007706973.666861.5723
ENSG00000110713homo_sapiensENSP0000031603272.444460.0556cyprinus_carpio_carpioENSCCRP0000007774573.340860.7986
ENSG00000110713homo_sapiensENSP0000031603286.277875.9444coturnix_japonicaENSCJPP0000500607586.469976.1136
ENSG00000110713homo_sapiensENSP0000031603273.277860.5556poecilia_latipinnaENSPLAP0000001943772.432759.8572
ENSG00000110713homo_sapiensENSP0000031603274.277862.3333sinocyclocheilus_grahamiENSSGRP0000003163374.03162.1262
ENSG00000110713homo_sapiensENSP0000031603255.722246.2778sinocyclocheilus_grahamiENSSGRP0000009139469.944258.0893
ENSG00000110713homo_sapiensENSP0000031603212.444410.2222sinocyclocheilus_grahamiENSSGRP0000000542474.666761.3333
ENSG00000110713homo_sapiensENSP0000031603217.444413.4444maylandia_zebraENSMZEP0000501015578.894560.804
ENSG00000110713homo_sapiensENSP0000031603270.558.0556maylandia_zebraENSMZEP0000501024972.431559.6461
ENSG00000110713homo_sapiensENSP0000031603231.777827maylandia_zebraENSMZEP0000503363375.362364.0316
ENSG00000110713homo_sapiensENSP000003160326855.3333tetraodon_nigroviridisENSTNIP0000001049871.83158.4507
ENSG00000110713homo_sapiensENSP0000031603273.722260.9444paramormyrops_kingsleyaeENSPKIP0000003714471.652359.2333
ENSG00000110713homo_sapiensENSP0000031603274.166761.1111scleropages_formosusENSSFOP0001506093572.712459.9129
ENSG00000110713homo_sapiensENSP0000031603274.944462leptobrachium_leishanenseENSLLEP0000000952975.027862.069
ENSG00000110713homo_sapiensENSP0000031603273.166760.1111scophthalmus_maximusENSSMAP0000002030471.537258.7724
ENSG00000110713homo_sapiensENSP0000031603272.666759.8889oryzias_melastigmaENSOMEP0000001658771.789259.1658

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000776colocalizes_with kinetochore1IDAHomo_sapiens(9606)Component
GO:0000973involved_in post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery1IBAHomo_sapiens(9606)Process
GO:0003713enables transcription coactivator activity1IMPHomo_sapiens(9606)Function
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005635located_in nuclear envelope2IDA,TASHomo_sapiens(9606)Component
GO:0005643part_of nuclear pore2IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006405involved_in RNA export from nucleus1IBAHomo_sapiens(9606)Process
GO:0006508involved_in proteolysis1IEAHomo_sapiens(9606)Process
GO:0006606involved_in protein import into nucleus1IBAHomo_sapiens(9606)Process
GO:0006913involved_in nucleocytoplasmic transport1TASHomo_sapiens(9606)Process
GO:0006999involved_in nuclear pore organization1NASHomo_sapiens(9606)Process
GO:0008139enables nuclear localization sequence binding1IBAHomo_sapiens(9606)Function
GO:0008236enables serine-type peptidase activity1IEAHomo_sapiens(9606)Function
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0017056enables structural constituent of nuclear pore3IBA,IMP,NASHomo_sapiens(9606)Function
GO:0031080part_of nuclear pore outer ring2IDA,NASHomo_sapiens(9606)Component
GO:0031965located_in nuclear membrane1IDAHomo_sapiens(9606)Component
GO:0034398involved_in telomere tethering at nuclear periphery1IBAHomo_sapiens(9606)Process
GO:0034399located_in nuclear periphery1IDAHomo_sapiens(9606)Component
GO:0042405located_in nuclear inclusion body1IDAHomo_sapiens(9606)Component
GO:0044614part_of nuclear pore cytoplasmic filaments1IBAHomo_sapiens(9606)Component
GO:0044615part_of nuclear pore nuclear basket1IDAHomo_sapiens(9606)Component
GO:0045893involved_in positive regulation of DNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IMPHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0051292involved_in nuclear pore complex assembly1IMPHomo_sapiens(9606)Process
GO:1990841enables promoter-specific chromatin binding1IMPHomo_sapiens(9606)Function
GO:1990904part_of ribonucleoprotein complex1IMPHomo_sapiens(9606)Component

Expression