RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000109674	Gene ID	55247	Accession	24573
Symbol	NEIL3	Alias	FGP2;FPG2;NEI3;ZGRF3;hFPG2;hNEI3	Full Name	nei like DNA glycosylase 3
Status	Confidence	Length	53063 bases	Strand	Plus strand
Position	4 : 177309874 - 177362936	RNA binding domain	zf-RanBP
Summary	NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000264596	zf-RanBP	PF00641	6e-06	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
37213665	Regulatory mechanisms and clinical applications of tumor-driven exosomal circRNAs in cancers.	Xiangyu Meng	2023-01-01	International journal of medical sciences
35031058	EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.	Ziwen Pan	2022-01-14	Molecular cancer

Name	Transcript ID	bp	Protein	Translation ID
NEIL3-201	ENST00000264596	2363	605aa	ENSP00000264596
NEIL3-202	ENST00000513321	1528	63aa	ENSP00000424735

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
2694	Subcutaneous Fat	2.45388273298897E-5	17903300
2709	Subcutaneous Fat	2.87687391937741E-5	17903300
2726	Abdominal Fat	1.93592959196742E-6	17903300
2738	Abdominal Fat	2.13718218899928E-6	17903300
2769	Intra-Abdominal Fat	3.05938989166865E-5	17903300
2778	Body Weights and Measures	3.53412189277869E-5	17903300
8312	Heart Rate	9.1026905905563E-7	17903306
8325	Heart Rate	6.88670489997163E-6	17903306
22259	Glucose	9.356e-005	-
42430	Platelet Function Tests	2.1314100E-005	-
42453	Platelet Function Tests	2.1314100E-005	-
70001	Selenium	3E-7	23698163
83235	Heart Rate	7E-6	17903306

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000109674	homo_sapiens	ENSP00000284503	35.241	21.988	homo_sapiens	ENSP00000264596	19.3388	12.0661
ENSG00000109674	homo_sapiens	ENSP00000347170	30.2564	17.9487	homo_sapiens	ENSP00000264596	19.5041	11.5702

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000109674	homo_sapiens	ENSP00000264596	96.6942	94.7107	nomascus_leucogenys	ENSNLEP00000020427	96.5347	94.5545
ENSG00000109674	homo_sapiens	ENSP00000264596	97.0248	96.5289	pan_paniscus	ENSPPAP00000024334	98.1605	97.6589
ENSG00000109674	homo_sapiens	ENSP00000264596	96.6942	95.0413	pongo_abelii	ENSPPYP00000038335	96.5347	94.8845
ENSG00000109674	homo_sapiens	ENSP00000264596	93.719	92.2314	pan_troglodytes	ENSPTRP00000028509	93.4102	91.9275
ENSG00000109674	homo_sapiens	ENSP00000264596	98.6777	98.1818	gorilla_gorilla	ENSGGOP00000016391	98.5149	98.0198
ENSG00000109674	homo_sapiens	ENSP00000264596	76.3636	66.7769	sarcophilus_harrisii	ENSSHAP00000008870	74.5161	65.1613
ENSG00000109674	homo_sapiens	ENSP00000264596	55.7025	48.9256	notamacropus_eugenii	ENSMEUP00000015277	56.2604	49.4157
ENSG00000109674	homo_sapiens	ENSP00000264596	67.1074	62.9752	choloepus_hoffmanni	ENSCHOP00000007162	67.1074	62.9752
ENSG00000109674	homo_sapiens	ENSP00000264596	75.7025	69.4215	dasypus_novemcinctus	ENSDNOP00000009504	88.2466	80.9249
ENSG00000109674	homo_sapiens	ENSP00000264596	59.6694	52.7273	erinaceus_europaeus	ENSEEUP00000009878	79.6909	70.4194
ENSG00000109674	homo_sapiens	ENSP00000264596	75.5372	69.4215	echinops_telfairi	ENSETEP00000007725	84.3173	77.4908
ENSG00000109674	homo_sapiens	ENSP00000264596	94.876	91.0744	callithrix_jacchus	ENSCJAP00000009988	94.7195	90.9241
ENSG00000109674	homo_sapiens	ENSP00000264596	95.0413	91.5703	cercocebus_atys	ENSCATP00000019989	95.515	92.0266
ENSG00000109674	homo_sapiens	ENSP00000264596	95.5372	92.3967	macaca_fascicularis	ENSMFAP00000005764	96.0133	92.8571
ENSG00000109674	homo_sapiens	ENSP00000264596	95.3719	92.2314	macaca_mulatta	ENSMMUP00000009704	95.8472	92.691
ENSG00000109674	homo_sapiens	ENSP00000264596	95.2066	92.2314	macaca_nemestrina	ENSMNEP00000025378	95.6811	92.691
ENSG00000109674	homo_sapiens	ENSP00000264596	95.0413	91.9008	papio_anubis	ENSPANP00000006567	95.515	92.3588
ENSG00000109674	homo_sapiens	ENSP00000264596	94.876	91.5703	mandrillus_leucophaeus	ENSMLEP00000022643	95.3488	92.0266
ENSG00000109674	homo_sapiens	ENSP00000264596	85.124	78.3471	tursiops_truncatus	ENSTTRP00000012548	84.9835	78.2178
ENSG00000109674	homo_sapiens	ENSP00000264596	85.2893	78.6777	vulpes_vulpes	ENSVVUP00000017096	85.4305	78.8079
ENSG00000109674	homo_sapiens	ENSP00000264596	82.9752	74.2149	mus_spretus	MGP_SPRETEiJ_P0087924	82.8383	74.0924
ENSG00000109674	homo_sapiens	ENSP00000264596	88.0992	80.1653	equus_asinus	ENSEASP00005032627	87.9538	80.033
ENSG00000109674	homo_sapiens	ENSP00000264596	85.124	78.1818	capra_hircus	ENSCHIP00000005007	84.9835	78.0528
ENSG00000109674	homo_sapiens	ENSP00000264596	86.281	80.6612	loxodonta_africana	ENSLAFP00000011858	86.711	81.0631
ENSG00000109674	homo_sapiens	ENSP00000264596	79.8347	73.3884	panthera_leo	ENSPLOP00000017617	81.5878	75
ENSG00000109674	homo_sapiens	ENSP00000264596	85.6198	78.6777	ailuropoda_melanoleuca	ENSAMEP00000003918	85.9038	78.9386
ENSG00000109674	homo_sapiens	ENSP00000264596	80	73.0579	bos_indicus_hybrid	ENSBIXP00005011938	77.44	70.72
ENSG00000109674	homo_sapiens	ENSP00000264596	87.438	79.6694	oryctolagus_cuniculus	ENSOCUP00000000900	88.02	80.1997
ENSG00000109674	homo_sapiens	ENSP00000264596	88.0992	80	equus_caballus	ENSECAP00000082163	87.9538	79.868
ENSG00000109674	homo_sapiens	ENSP00000264596	84.7934	78.1818	canis_lupus_familiaris	ENSCAFP00845025538	84.9338	78.3113
ENSG00000109674	homo_sapiens	ENSP00000264596	85.2893	78.5124	panthera_pardus	ENSPPRP00000009522	87.1622	80.2365
ENSG00000109674	homo_sapiens	ENSP00000264596	87.2727	80.6612	marmota_marmota_marmota	ENSMMMP00000014381	86.9852	80.3954
ENSG00000109674	homo_sapiens	ENSP00000264596	85.6198	78.3471	balaenoptera_musculus	ENSBMSP00010027918	85.4785	78.2178
ENSG00000109674	homo_sapiens	ENSP00000264596	86.6116	78.5124	cavia_porcellus	ENSCPOP00000002978	86.3262	78.2537
ENSG00000109674	homo_sapiens	ENSP00000264596	84.9587	78.1818	felis_catus	ENSFCAP00000004585	86.8243	79.8987
ENSG00000109674	homo_sapiens	ENSP00000264596	85.2893	79.5041	ursus_americanus	ENSUAMP00000000847	85.5721	79.7678
ENSG00000109674	homo_sapiens	ENSP00000264596	68.4297	59.5041	monodelphis_domestica	ENSMODP00000004671	73.2743	63.7168
ENSG00000109674	homo_sapiens	ENSP00000264596	81.3223	75.2066	bison_bison_bison	ENSBBBP00000022887	81.1881	75.0825
ENSG00000109674	homo_sapiens	ENSP00000264596	85.4545	78.3471	monodon_monoceros	ENSMMNP00015008261	85.3135	78.2178
ENSG00000109674	homo_sapiens	ENSP00000264596	84.4628	78.1818	sus_scrofa	ENSSSCP00000016711	85.7383	79.3624
ENSG00000109674	homo_sapiens	ENSP00000264596	90.5785	84.6281	microcebus_murinus	ENSMICP00000008327	91.1814	85.1913
ENSG00000109674	homo_sapiens	ENSP00000264596	84.7934	76.8595	octodon_degus	ENSODEP00000005429	84.514	76.6063
ENSG00000109674	homo_sapiens	ENSP00000264596	82.8099	73.0579	jaculus_jaculus	ENSJJAP00000021193	83.0846	73.3002
ENSG00000109674	homo_sapiens	ENSP00000264596	84.9587	78.1818	ovis_aries_rambouillet	ENSOARP00020032770	84.8185	78.0528
ENSG00000109674	homo_sapiens	ENSP00000264596	74.3802	68.595	ursus_maritimus	ENSUMAP00000032473	87.0406	80.2708
ENSG00000109674	homo_sapiens	ENSP00000264596	68.0992	61.157	ochotona_princeps	ENSOPRP00000005003	68.2119	61.2583
ENSG00000109674	homo_sapiens	ENSP00000264596	85.6198	78.3471	delphinapterus_leucas	ENSDLEP00000016300	85.4785	78.2178
ENSG00000109674	homo_sapiens	ENSP00000264596	83.8017	76.6942	physeter_catodon	ENSPCTP00005006482	83.6634	76.5677
ENSG00000109674	homo_sapiens	ENSP00000264596	82.4793	74.0496	mus_caroli	MGP_CAROLIEiJ_P0084438	82.3432	73.9274
ENSG00000109674	homo_sapiens	ENSP00000264596	82.9752	73.8843	mus_musculus	ENSMUSP00000041909	82.8383	73.7624
ENSG00000109674	homo_sapiens	ENSP00000264596	72.3967	65.9504	mustela_putorius_furo	ENSMPUP00000012047	84.7195	77.176
ENSG00000109674	homo_sapiens	ENSP00000264596	88.595	85.124	aotus_nancymaae	ENSANAP00000017188	91.1565	87.585
ENSG00000109674	homo_sapiens	ENSP00000264596	94.3802	90.7438	saimiri_boliviensis_boliviensis	ENSSBOP00000032833	94.3802	90.7438
ENSG00000109674	homo_sapiens	ENSP00000264596	77.0248	70.0826	vicugna_pacos	ENSVPAP00000004655	77.1523	70.1987
ENSG00000109674	homo_sapiens	ENSP00000264596	94.2149	90.2479	chlorocebus_sabaeus	ENSCSAP00000014976	94.8419	90.8486
ENSG00000109674	homo_sapiens	ENSP00000264596	69.2562	63.6364	tupaia_belangeri	ENSTBEP00000006242	69.6013	63.9535
ENSG00000109674	homo_sapiens	ENSP00000264596	84.2975	77.686	phocoena_sinus	ENSPSNP00000016806	84.1584	77.5578
ENSG00000109674	homo_sapiens	ENSP00000264596	84.4628	78.1818	camelus_dromedarius	ENSCDRP00005031044	84.3234	78.0528
ENSG00000109674	homo_sapiens	ENSP00000264596	86.7769	81.157	carlito_syrichta	ENSTSYP00000013469	87.7926	82.107
ENSG00000109674	homo_sapiens	ENSP00000264596	85.4545	79.0083	panthera_tigris_altaica	ENSPTIP00000013136	87.3311	80.7432
ENSG00000109674	homo_sapiens	ENSP00000264596	81.8182	72.7273	rattus_norvegicus	ENSRNOP00000015623	81.8182	72.7273
ENSG00000109674	homo_sapiens	ENSP00000264596	89.7521	83.9669	prolemur_simus	ENSPSMP00000029218	91.1074	85.2349
ENSG00000109674	homo_sapiens	ENSP00000264596	65.7851	59.0083	sorex_araneus	ENSSARP00000004535	65.6766	58.9109
ENSG00000109674	homo_sapiens	ENSP00000264596	83.4711	74.2149	peromyscus_maniculatus_bairdii	ENSPEMP00000017727	83.3333	74.0924
ENSG00000109674	homo_sapiens	ENSP00000264596	82.6446	76.0331	bos_mutus	ENSBMUP00000012124	82.5082	75.9076
ENSG00000109674	homo_sapiens	ENSP00000264596	82.6446	74.2149	mus_spicilegus	ENSMSIP00000001415	82.5082	74.0924
ENSG00000109674	homo_sapiens	ENSP00000264596	84.7934	76.5289	cricetulus_griseus_chok1gshd	ENSCGRP00001019038	84.6535	76.4026
ENSG00000109674	homo_sapiens	ENSP00000264596	84.9587	77.3554	pteropus_vampyrus	ENSPVAP00000002133	85.0993	77.4834
ENSG00000109674	homo_sapiens	ENSP00000264596	78.3471	68.0992	myotis_lucifugus	ENSMLUP00000006896	78.8686	68.5524
ENSG00000109674	homo_sapiens	ENSP00000264596	78.843	69.4215	vombatus_ursinus	ENSVURP00010009357	76.9355	67.7419
ENSG00000109674	homo_sapiens	ENSP00000264596	84.9587	78.3471	rhinolophus_ferrumequinum	ENSRFEP00010026201	85.8097	79.1319
ENSG00000109674	homo_sapiens	ENSP00000264596	75.2066	67.9339	neovison_vison	ENSNVIP00000011749	82.878	74.8634
ENSG00000109674	homo_sapiens	ENSP00000264596	80.4959	73.5537	bos_taurus	ENSBTAP00000061910	78.5484	71.7742
ENSG00000109674	homo_sapiens	ENSP00000264596	87.7686	78.5124	heterocephalus_glaber_female	ENSHGLP00000009258	87.6238	78.3828
ENSG00000109674	homo_sapiens	ENSP00000264596	93.719	90.7438	rhinopithecus_bieti	ENSRBIP00000005075	95.4545	92.4242
ENSG00000109674	homo_sapiens	ENSP00000264596	81.6529	75.0413	canis_lupus_dingo	ENSCAFP00020028647	84.4444	77.6068
ENSG00000109674	homo_sapiens	ENSP00000264596	83.6364	76.1983	sciurus_vulgaris	ENSSVLP00005003928	87.5433	79.7578
ENSG00000109674	homo_sapiens	ENSP00000264596	79.6694	70.0826	phascolarctos_cinereus	ENSPCIP00000033116	77.7419	68.3871
ENSG00000109674	homo_sapiens	ENSP00000264596	60.4959	54.5455	procavia_capensis	ENSPCAP00000005961	71.7647	64.7059
ENSG00000109674	homo_sapiens	ENSP00000264596	82.314	74.5455	bos_grunniens	ENSBGRP00000013742	69.5531	62.9888
ENSG00000109674	homo_sapiens	ENSP00000264596	85.6198	77.5207	chinchilla_lanigera	ENSCLAP00000022834	85.3377	77.2652
ENSG00000109674	homo_sapiens	ENSP00000264596	85.124	78.3471	cervus_hanglu_yarkandensis	ENSCHYP00000033340	84.9835	78.2178
ENSG00000109674	homo_sapiens	ENSP00000264596	84.9587	77.686	catagonus_wagneri	ENSCWAP00000003140	84.8185	77.5578
ENSG00000109674	homo_sapiens	ENSP00000264596	87.2727	80.3306	ictidomys_tridecemlineatus	ENSSTOP00000014548	86.9852	80.0659
ENSG00000109674	homo_sapiens	ENSP00000264596	87.9339	81.3223	otolemur_garnettii	ENSOGAP00000011309	87.7888	81.1881
ENSG00000109674	homo_sapiens	ENSP00000264596	95.0413	91.5703	cebus_imitator	ENSCCAP00000003721	94.8845	91.4191
ENSG00000109674	homo_sapiens	ENSP00000264596	86.6116	79.8347	urocitellus_parryii	ENSUPAP00010017339	86.3262	79.5717
ENSG00000109674	homo_sapiens	ENSP00000264596	84.7934	78.1818	moschus_moschiferus	ENSMMSP00000002816	84.514	77.9242
ENSG00000109674	homo_sapiens	ENSP00000264596	93.5537	90.5785	rhinopithecus_roxellana	ENSRROP00000000050	95.2862	92.2559
ENSG00000109674	homo_sapiens	ENSP00000264596	83.6364	73.719	mus_pahari	MGP_PahariEiJ_P0047328	83.4984	73.5974
ENSG00000109674	homo_sapiens	ENSP00000264596	62.8099	58.0165	propithecus_coquereli	ENSPCOP00000003642	89.8345	82.9787
ENSG00000109674	homo_sapiens	ENSP00000264596	37.1901	28.595	petromyzon_marinus	ENSPMAP00000003123	56.391	43.3584
ENSG00000109674	homo_sapiens	ENSP00000264596	60.6612	47.438	callorhinchus_milii	ENSCMIP00000005403	70.3065	54.9808
ENSG00000109674	homo_sapiens	ENSP00000264596	42.1488	35.2066	latimeria_chalumnae	ENSLACP00000000340	66.5796	55.6136
ENSG00000109674	homo_sapiens	ENSP00000264596	63.9669	50.9091	lepisosteus_oculatus	ENSLOCP00000016819	66.8394	53.1952
ENSG00000109674	homo_sapiens	ENSP00000264596	60.9917	47.9339	clupea_harengus	ENSCHAP00000001921	70.1521	55.1331
ENSG00000109674	homo_sapiens	ENSP00000264596	63.4711	51.405	danio_rerio	ENSDARP00000109273	67.6056	54.7535
ENSG00000109674	homo_sapiens	ENSP00000264596	62.6446	51.5702	carassius_auratus	ENSCARP00000062688	66.7253	54.9296
ENSG00000109674	homo_sapiens	ENSP00000264596	57.3554	44.6281	astyanax_mexicanus	ENSAMXP00000015818	63.7868	49.6324
ENSG00000109674	homo_sapiens	ENSP00000264596	57.686	44.2975	ictalurus_punctatus	ENSIPUP00000005648	62.2103	47.7718
ENSG00000109674	homo_sapiens	ENSP00000264596	60.8264	49.7521	esox_lucius	ENSELUP00000040367	62.585	51.1905
ENSG00000109674	homo_sapiens	ENSP00000264596	55.7025	44.6281	electrophorus_electricus	ENSEEEP00000012750	61.3843	49.1803
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	50.4132	oncorhynchus_kisutch	ENSOKIP00005015557	63.4975	51.7827
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	50.4132	oncorhynchus_mykiss	ENSOMYP00000025753	63.4975	51.7827
ENSG00000109674	homo_sapiens	ENSP00000264596	61.6529	50.2479	salmo_salar	ENSSSAP00000100640	63.3277	51.6129
ENSG00000109674	homo_sapiens	ENSP00000264596	57.5207	46.6116	salmo_trutta	ENSSTUP00000077507	64.684	52.4164
ENSG00000109674	homo_sapiens	ENSP00000264596	57.0248	43.9669	gadus_morhua	ENSGMOP00000018119	59.792	46.1005
ENSG00000109674	homo_sapiens	ENSP00000264596	61.3223	48.2645	fundulus_heteroclitus	ENSFHEP00000025354	64.2981	50.6066
ENSG00000109674	homo_sapiens	ENSP00000264596	61.3223	48.2645	poecilia_reticulata	ENSPREP00000014598	67.9487	53.4799
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	48.0992	xiphophorus_maculatus	ENSXMAP00000024646	64.4828	50.1724
ENSG00000109674	homo_sapiens	ENSP00000264596	61.3223	47.9339	oryzias_latipes	ENSORLP00000025238	64.2981	50.26
ENSG00000109674	homo_sapiens	ENSP00000264596	61.3223	47.7686	cyclopterus_lumpus	ENSCLMP00005018258	64.076	49.9136
ENSG00000109674	homo_sapiens	ENSP00000264596	64.1322	50.9091	oreochromis_niloticus	ENSONIP00000001487	66.7814	53.012
ENSG00000109674	homo_sapiens	ENSP00000264596	63.6364	50.5785	haplochromis_burtoni	ENSHBUP00000000037	66.2651	52.6678
ENSG00000109674	homo_sapiens	ENSP00000264596	63.9669	50.7438	astatotilapia_calliptera	ENSACLP00000016527	66.6093	52.8399
ENSG00000109674	homo_sapiens	ENSP00000264596	64.6281	50.7438	sparus_aurata	ENSSAUP00010022672	67.1821	52.7491
ENSG00000109674	homo_sapiens	ENSP00000264596	49.5868	38.843	lates_calcarifer	ENSLCAP00010047887	64.9351	50.8658
ENSG00000109674	homo_sapiens	ENSP00000264596	64.9587	52.3967	xenopus_tropicalis	ENSXETP00000062127	68.4669	55.2265
ENSG00000109674	homo_sapiens	ENSP00000264596	73.0579	61.8182	chrysemys_picta_bellii	ENSCPBP00000004144	73.3002	62.0232
ENSG00000109674	homo_sapiens	ENSP00000264596	70.4132	59.5041	sphenodon_punctatus	ENSSPUP00000012308	75	63.3803
ENSG00000109674	homo_sapiens	ENSP00000264596	74.2149	61.9835	crocodylus_porosus	ENSCPRP00005016389	75.5892	63.1313
ENSG00000109674	homo_sapiens	ENSP00000264596	67.7686	56.5289	anas_platyrhynchos_platyrhynchos	ENSAPLP00000013102	70.568	58.864
ENSG00000109674	homo_sapiens	ENSP00000264596	65.6198	54.3802	gallus_gallus	ENSGALP00010006080	67.8633	56.2393
ENSG00000109674	homo_sapiens	ENSP00000264596	66.4463	56.0331	meleagris_gallopavo	ENSMGAP00000006779	68.7179	57.9487
ENSG00000109674	homo_sapiens	ENSP00000264596	60.6612	50.4132	serinus_canaria	ENSSCAP00000013720	71.54	59.4542
ENSG00000109674	homo_sapiens	ENSP00000264596	62.1488	52.0661	parus_major	ENSPMJP00000002155	67.7477	56.7568
ENSG00000109674	homo_sapiens	ENSP00000264596	57.1901	47.1074	anolis_carolinensis	ENSACAP00000029345	64.9156	53.4709
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	49.5868	neolamprologus_brichardi	ENSNBRP00000017167	70.8333	56.8182
ENSG00000109674	homo_sapiens	ENSP00000264596	68.595	56.8595	naja_naja	ENSNNAP00000011793	70.8191	58.7031
ENSG00000109674	homo_sapiens	ENSP00000264596	70.9091	60.3306	podarcis_muralis	ENSPMRP00000015479	71.9799	61.2416
ENSG00000109674	homo_sapiens	ENSP00000264596	60.8264	50.4132	geospiza_fortis	ENSGFOP00000016026	71.7349	59.4542
ENSG00000109674	homo_sapiens	ENSP00000264596	62.314	52.3967	taeniopygia_guttata	ENSTGUP00000006633	62.9382	52.9215
ENSG00000109674	homo_sapiens	ENSP00000264596	60.8264	48.9256	kryptolebias_marmoratus	ENSKMAP00000013215	66.187	53.2374
ENSG00000109674	homo_sapiens	ENSP00000264596	68.595	56.6942	salvator_merianae	ENSSMRP00000012129	70.1013	57.9392
ENSG00000109674	homo_sapiens	ENSP00000264596	60.6612	47.7686	oryzias_javanicus	ENSOJAP00000020125	63.8261	50.2609
ENSG00000109674	homo_sapiens	ENSP00000264596	62.4793	50.2479	amphilophus_citrinellus	ENSACIP00000002875	66.7845	53.7102
ENSG00000109674	homo_sapiens	ENSP00000264596	60.8264	48.4298	dicentrarchus_labrax	ENSDLAP00005051790	62.4788	49.7453
ENSG00000109674	homo_sapiens	ENSP00000264596	62.8099	50.5785	amphiprion_percula	ENSAPEP00000001550	67.9785	54.7406
ENSG00000109674	homo_sapiens	ENSP00000264596	59.5041	46.4463	oryzias_sinensis	ENSOSIP00000022365	65.2174	50.9058
ENSG00000109674	homo_sapiens	ENSP00000264596	44.6281	37.1901	pelodiscus_sinensis	ENSPSIP00000013533	70.3125	58.5938
ENSG00000109674	homo_sapiens	ENSP00000264596	71.5703	59.8347	chelonoidis_abingdonii	ENSCABP00000008694	73.0185	61.0455
ENSG00000109674	homo_sapiens	ENSP00000264596	61.4876	48.595	seriola_dumerili	ENSSDUP00000001930	62.9442	49.7462
ENSG00000109674	homo_sapiens	ENSP00000264596	62.314	48.7603	cottoperca_gobio	ENSCGOP00000009610	53.3239	41.7256
ENSG00000109674	homo_sapiens	ENSP00000264596	64.9587	53.0578	struthio_camelus_australis	ENSSCUP00000010132	71.7153	58.5766
ENSG00000109674	homo_sapiens	ENSP00000264596	67.438	56.1983	anser_brachyrhynchus	ENSABRP00000018609	70.4663	58.7219
ENSG00000109674	homo_sapiens	ENSP00000264596	60.8264	47.6033	gasterosteus_aculeatus	ENSGACP00000021851	63.1218	49.3997
ENSG00000109674	homo_sapiens	ENSP00000264596	63.6364	49.0909	cynoglossus_semilaevis	ENSCSEP00000005921	60.2504	46.4789
ENSG00000109674	homo_sapiens	ENSP00000264596	62.314	48.7603	poecilia_formosa	ENSPFOP00000018976	65.338	51.1265
ENSG00000109674	homo_sapiens	ENSP00000264596	63.8017	50.2479	myripristis_murdjan	ENSMMDP00005044601	66.0959	52.0548
ENSG00000109674	homo_sapiens	ENSP00000264596	63.6364	50.5785	sander_lucioperca	ENSSLUP00000022800	66.1512	52.5773
ENSG00000109674	homo_sapiens	ENSP00000264596	60.4959	49.7521	strigops_habroptila	ENSSHBP00005015365	73.3467	60.3206
ENSG00000109674	homo_sapiens	ENSP00000264596	24.2975	18.6777	amphiprion_ocellaris	ENSAOCP00000015943	73.1343	56.2189
ENSG00000109674	homo_sapiens	ENSP00000264596	62.9752	50.7438	amphiprion_ocellaris	ENSAOCP00000014053	68.1574	54.9195
ENSG00000109674	homo_sapiens	ENSP00000264596	61.3223	50.7438	hucho_hucho	ENSHHUP00000006368	62.9881	52.1222
ENSG00000109674	homo_sapiens	ENSP00000264596	62.314	49.7521	betta_splendens	ENSBSLP00000041908	64.8881	51.8072
ENSG00000109674	homo_sapiens	ENSP00000264596	57.686	44.9587	pygocentrus_nattereri	ENSPNAP00000032209	65.2336	50.8411
ENSG00000109674	homo_sapiens	ENSP00000264596	63.6364	51.5702	anabas_testudineus	ENSATEP00000005974	66.494	53.886
ENSG00000109674	homo_sapiens	ENSP00000264596	63.8017	50.9091	seriola_lalandi_dorsalis	ENSSLDP00000030638	66.323	52.921
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	48.595	labrus_bergylta	ENSLBEP00000019613	67.0251	52.6882
ENSG00000109674	homo_sapiens	ENSP00000264596	62.9752	50.5785	pundamilia_nyererei	ENSPNYP00000028264	68.2796	54.8387
ENSG00000109674	homo_sapiens	ENSP00000264596	62.1488	49.2562	mastacembelus_armatus	ENSMAMP00000048271	53.0324	42.031
ENSG00000109674	homo_sapiens	ENSP00000264596	64.1322	50.5785	stegastes_partitus	ENSSPAP00000011919	68.1898	53.7786
ENSG00000109674	homo_sapiens	ENSP00000264596	61.8182	50.4132	oncorhynchus_tshawytscha	ENSOTSP00005099294	63.4975	51.7827
ENSG00000109674	homo_sapiens	ENSP00000264596	63.6364	50.2479	acanthochromis_polyacanthus	ENSAPOP00000018686	66.1512	52.2337
ENSG00000109674	homo_sapiens	ENSP00000264596	61.4876	51.2397	aquila_chrysaetos_chrysaetos	ENSACCP00020015287	72.5146	60.4288
ENSG00000109674	homo_sapiens	ENSP00000264596	62.4793	49.5868	nothobranchius_furzeri	ENSNFUP00015011224	66.0839	52.4476
ENSG00000109674	homo_sapiens	ENSP00000264596	63.4711	49.9174	cyprinodon_variegatus	ENSCVAP00000003203	66.2069	52.069
ENSG00000109674	homo_sapiens	ENSP00000264596	61.157	48.7603	denticeps_clupeoides	ENSDCDP00000014942	61.3599	48.9221
ENSG00000109674	homo_sapiens	ENSP00000264596	58.1818	45.6198	larimichthys_crocea	ENSLCRP00005052088	63.8838	50.0907
ENSG00000109674	homo_sapiens	ENSP00000264596	60.3306	46.9422	takifugu_rubripes	ENSTRUP00000073290	60.9349	47.4124
ENSG00000109674	homo_sapiens	ENSP00000264596	60	50.4132	ficedula_albicollis	ENSFALP00000012116	66.362	55.7587
ENSG00000109674	homo_sapiens	ENSP00000264596	57.5207	45.124	hippocampus_comes	ENSHCOP00000007024	66.6667	52.2989
ENSG00000109674	homo_sapiens	ENSP00000264596	38.5124	30.7438	cyprinus_carpio_carpio	ENSCCRP00000152039	55.4762	44.2857
ENSG00000109674	homo_sapiens	ENSP00000264596	63.1405	51.7355	cyprinus_carpio_carpio	ENSCCRP00000080370	66.9002	54.8161
ENSG00000109674	homo_sapiens	ENSP00000264596	67.1074	55.8678	coturnix_japonica	ENSCJPP00005011509	69.2833	57.6792
ENSG00000109674	homo_sapiens	ENSP00000264596	61.9835	48.4298	poecilia_latipinna	ENSPLAP00000008195	64.9913	50.7799
ENSG00000109674	homo_sapiens	ENSP00000264596	62.9752	51.9008	sinocyclocheilus_grahami	ENSSGRP00000052499	66.725	54.9912
ENSG00000109674	homo_sapiens	ENSP00000264596	39.3388	29.9174	sinocyclocheilus_grahami	ENSSGRP00000045053	57.9075	44.0389
ENSG00000109674	homo_sapiens	ENSP00000264596	63.9669	50.7438	maylandia_zebra	ENSMZEP00005002130	66.6093	52.8399
ENSG00000109674	homo_sapiens	ENSP00000264596	60.6612	48.595	tetraodon_nigroviridis	ENSTNIP00000016012	62.309	49.9151
ENSG00000109674	homo_sapiens	ENSP00000264596	58.6777	45.7851	paramormyrops_kingsleyae	ENSPKIP00000022738	63.7343	49.7307
ENSG00000109674	homo_sapiens	ENSP00000264596	59.0083	45.7851	scleropages_formosus	ENSSFOP00015025664	62.087	48.1739
ENSG00000109674	homo_sapiens	ENSP00000264596	67.1074	52.7273	leptobrachium_leishanense	ENSLLEP00000028939	72.242	56.7616
ENSG00000109674	homo_sapiens	ENSP00000264596	61.9835	49.0909	scophthalmus_maximus	ENSSMAP00000015728	58.8697	46.6248
ENSG00000109674	homo_sapiens	ENSP00000264596	61.157	48.2645	oryzias_melastigma	ENSOMEP00000030508	63.9033	50.4318

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000405	enables bubble DNA binding	1	ISS	Homo_sapiens(9606)	Function
GO:0003684	enables damaged DNA binding	1	ISS	Homo_sapiens(9606)	Function
GO:0003690	enables double-stranded DNA binding	1	ISS	Homo_sapiens(9606)	Function
GO:0003697	enables single-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003906	enables DNA-(apurinic or apyrimidinic site) endonuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005694	located_in chromosome	1	IEA	Homo_sapiens(9606)	Component
GO:0006284	involved_in base-excision repair	3	IBA,IDA,ISS	Homo_sapiens(9606)	Process
GO:0006285	involved_in base-excision repair, AP site formation	1	TAS	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0019104	enables DNA N-glycosylase activity	4	IBA,IDA,ISS,TAS	Homo_sapiens(9606)	Function
GO:0036297	involved_in interstrand cross-link repair	1	ISS	Homo_sapiens(9606)	Process
GO:0045007	involved_in depurination	1	TAS	Homo_sapiens(9606)	Process
GO:0140078	enables class I DNA-(apurinic or apyrimidinic site) endonuclease activity	1	IEA	Homo_sapiens(9606)	Function
GO:1904931	enables MCM complex binding	1	ISS	Homo_sapiens(9606)	Function