Ensembl ID ENSG00000109674 Gene ID 55247 Accession 24573
Gene Symbol NEIL3 Alias FGP2;FPG2;NEI3;ZGRF3;hFPG2;hNEI3 Full Name nei like DNA glycosylase 3
Position 4 : 177309874 - 177362936 Length 53063 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

ENSG00000109674 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000109674 NEIL3 3.06 1.18e-70 KIRC
ENSG00000109674 NEIL3 1.45 8.08e-24 HNSC
ENSG00000109674 NEIL3 3.40 4.61e-177 BRCA
ENSG00000109674 NEIL3 1.33 6.76e-29 COAD
ENSG00000109674 NEIL3 2.57 6.60e-11 KICH
ENSG00000109674 NEIL3 4.20 4.19e-161 LUSC
ENSG00000109674 NEIL3 1.95 3.62e-20 PRAD
ENSG00000109674 NEIL3 4.30 7.28e-20 GBM
ENSG00000109674 NEIL3 4.06 4.51e-32 KIRP
ENSG00000109674 NEIL3 4.14 1.38e-62 LIHC
ENSG00000109674 NEIL3 1.35 7.74e-14 STAD
ENSG00000109674 NEIL3 3.28 7.83e-65 UCEC
ENSG00000109674 NEIL3 6.17 4.95e-26 CESC
ENSG00000109674 NEIL3 4.28 1.28e-83 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000109674 NEIL3 tumor 19426544
ENSG00000109674 NEIL3 prostate cancer 21810555
ENSG00000109674 NEIL3 Cancer 27042257
ENSG00000109674 NEIL3 cancer 28918054
ENSG00000109674 NEIL3 cancer 29348879
ENSG00000109674 NEIL3 cancer 31614656
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000109674 NEIL3 STAD 0.033 low
ENSG00000109674 NEIL3 CHOL 0.0095 high
ENSG00000109674 NEIL3 UVM 0.00073 high
ENSG00000109674 NEIL3 PAAD 0.00011 high
ENSG00000109674 NEIL3 UCEC 0.00058 high
ENSG00000109674 NEIL3 THCA 0.022 high
ENSG00000109674 NEIL3 PCPG 0.0066 high
ENSG00000109674 NEIL3 THYM 0.0016 low
ENSG00000109674 NEIL3 DLBC 0.046 low
ENSG00000109674 NEIL3 PRAD 0.018 high
ENSG00000109674 NEIL3 BLCA 0.017 high
ENSG00000109674 NEIL3 CESC 0.015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000109674 NEIL3 CHOL Del 3.188398 0.390957 0.600927 0.611111
ENSG00000109674 NEIL3 LUSC Del 13.888956 0.174607 0.406342 0.674651
ENSG00000109674 NEIL3 LUAD Del 7.259825 0.108685 0.317404 0.366279
ENSG00000109674 NEIL3 LGG Del 10.077667 0.104677 0.466241 0.257310
ENSG00000109674 NEIL3 CESC Del 2.353336 0.096521 0.467729 0.372881
ENSG00000109674 NEIL3 ACC Del 1.203643 0.119091 0.533442 0.166667
ENSG00000109674 NEIL3 READ Del 0.779461 0.074801 0.429366 0.418182
ENSG00000109674 NEIL3 COAD Del 9.074382 0.107545 0.451316 0.334812
ENSG00000109674 NEIL3 SARC Del 6.360856 0.239278 0.507833 0.338521
ENSG00000109674 NEIL3 GBM Del 2.748839 0.074491 0.457469 0.145581
ENSG00000109674 NEIL3 PAAD Del 0.903299 0.050014 0.290149 0.184783
ENSG00000109674 NEIL3 ESCA Del 2.856269 0.154160 0.433097 0.538043
ENSG00000109674 NEIL3 SKCM Del 0.899793 0.069915 0.431818 0.258856
ENSG00000109674 NEIL3 HNSC Del 9.430719 0.118635 0.376029 0.365900
ENSG00000109674 NEIL3 LIHC Del 12.991960 0.188147 0.577791 0.454054
ENSG00000109674 NEIL3 PCPG Del 0.785328 0.060147 0.545798 0.080247
ENSG00000109674 NEIL3 BLCA Del 9.986533 0.179380 0.396405 0.421569
ENSG00000109674 NEIL3 BRCA Del 7.681657 0.105258 0.412084 0.315741
ENSG00000109674 NEIL3 STAD Del 13.617132 0.168412 0.378137 0.437642
ENSG00000109674 NEIL3 UCEC Del 3.639493 0.078136 0.473365 0.226345
ENSG00000109674 NEIL3 KIRC Del 0.696795 0.024401 0.329030 0.147727
ENSG00000109674 NEIL3 OV Del 19.313053 0.377151 0.647121 0.697755