RBP Type	Non-canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000108953	Gene ID	7531	Accession	12851
Symbol	YWHAE	Alias	MDS;HEL2;MDCR;KCIP-1;14-3-3E	Full Name	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
Status	Confidence	Length	55948 bases	Strand	Minus strand
Position	17 : 1344275 - 1400222	RNA binding domain	N.A.
Summary	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
YWHAE-201	ENST00000264335	2052	255aa	ENSP00000264335
YWHAE-202	ENST00000466227	1377	109aa	ENSP00000464883
YWHAE-208	ENST00000571732	1818	233aa	ENSP00000461762
YWHAE-210	ENST00000573026	780	38aa	ENSP00000458386
YWHAE-206	ENST00000496706	732	115aa	ENSP00000466324
YWHAE-211	ENST00000573196	739	94aa	ENSP00000461766
YWHAE-212	ENST00000575977	540	107aa	ENSP00000460712
YWHAE-203	ENST00000469398	676	No protein	-
YWHAE-204	ENST00000486241	691	No protein	-
YWHAE-205	ENST00000489287	465	No protein	-
YWHAE-213	ENST00000576854	1374	No protein	-
YWHAE-209	ENST00000572108	258	No protein	-
YWHAE-207	ENST00000498643	312	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
18853	Platelet Count	7.552e-005	-
47466	Breast Density	6.9046861E-006	-
47471	Breast Density	1.3327706E-005	-
86052	Schizophrenia	3E-6	26198764

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108953	homo_sapiens	ENSP00000300161	80.8943	67.4797	homo_sapiens	ENSP00000264335	78.0392	65.098
ENSG00000108953	homo_sapiens	ENSP00000340989	76.6129	60.4839	homo_sapiens	ENSP00000264335	74.5098	58.8235
ENSG00000108953	homo_sapiens	ENSP00000379288	81.6327	69.7959	homo_sapiens	ENSP00000264335	78.4314	67.0588
ENSG00000108953	homo_sapiens	ENSP00000238081	80.4082	65.7143	homo_sapiens	ENSP00000264335	77.2549	63.1373
ENSG00000108953	homo_sapiens	ENSP00000248975	77.2358	64.2276	homo_sapiens	ENSP00000264335	74.5098	61.9608
ENSG00000108953	homo_sapiens	ENSP00000306330	76.9231	64.3725	homo_sapiens	ENSP00000264335	74.5098	62.3529
ENSG00000108953	homo_sapiens	ENSP00000487356	100	100	homo_sapiens	ENSP00000264335	100	100

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.6078	nomascus_leucogenys	ENSNLEP00000043073	99.6078	99.6078
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	pan_paniscus	ENSPPAP00000014188	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	pongo_abelii	ENSPPYP00000024244	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	pan_troglodytes	ENSPTRP00000014538	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	gorilla_gorilla	ENSGGOP00000040662	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	ornithorhynchus_anatinus	ENSOANP00000044694	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	70.1961	67.0588	sarcophilus_harrisii	ENSSHAP00000036159	96.2366	91.9355
ENSG00000108953	homo_sapiens	ENSP00000264335	100	99.6078	sarcophilus_harrisii	ENSSHAP00000024879	83.0619	82.7362
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	92.9412	notamacropus_eugenii	ENSMEUP00000014107	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	88.2353	86.2745	choloepus_hoffmanni	ENSCHOP00000009609	96.9828	94.8276
ENSG00000108953	homo_sapiens	ENSP00000264335	86.6667	86.6667	choloepus_hoffmanni	ENSCHOP00000005202	92.0833	92.0833
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	dasypus_novemcinctus	ENSDNOP00000026337	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	echinops_telfairi	ENSETEP00000009787	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	95.6863	94.5098	callithrix_jacchus	ENSCJAP00000092796	94.9416	93.7743
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	cercocebus_atys	ENSCATP00000040192	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	93.3333	macaca_fascicularis	ENSMFAP00000041761	99.1667	99.1667
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	macaca_mulatta	ENSMMUP00000048707	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	macaca_nemestrina	ENSMNEP00000040276	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	papio_anubis	ENSPANP00000019471	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mandrillus_leucophaeus	ENSMLEP00000018262	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	tursiops_truncatus	ENSTTRP00000015718	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	93.3333	vulpes_vulpes	ENSVVUP00000029599	97.541	97.541
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mus_spretus	MGP_SPRETEiJ_P0029697	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	equus_asinus	ENSEASP00005060355	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	73.3333	69.4118	capra_hircus	ENSCHIP00000030705	90.7767	85.9223
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	loxodonta_africana	ENSLAFP00000005000	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	92.549	91.3726	panthera_leo	ENSPLOP00000016134	93.2806	92.0949
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	panthera_leo	ENSPLOP00000021618	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	87.0588	86.6667	ailuropoda_melanoleuca	ENSAMEP00000036550	86.0465	85.6589
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	89.4118	bos_indicus_hybrid	ENSBIXP00005033091	45.0677	44.1006
ENSG00000108953	homo_sapiens	ENSP00000264335	95.6863	92.549	oryctolagus_cuniculus	ENSOCUP00000045681	55.9633	54.1284
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	89.0196	equus_caballus	ENSECAP00000007582	94.7368	91.9028
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	canis_lupus_familiaris	ENSCAFP00845019789	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	panthera_pardus	ENSPPRP00000006716	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	35.6863	34.902	marmota_marmota_marmota	ENSMMMP00000027625	87.5	85.5769
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	balaenoptera_musculus	ENSBMSP00010025275	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	cavia_porcellus	ENSCPOP00000029570	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	felis_catus	ENSFCAP00000048295	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	74.1176	66.2745	monodelphis_domestica	ENSMODP00000012735	75.2988	67.3307
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	bison_bison_bison	ENSBBBP00000013347	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	59.2157	50.9804	monodon_monoceros	ENSMMNP00015012907	31.9239	27.4841
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	sus_scrofa	ENSSSCP00000038227	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.6078	microcebus_murinus	ENSMICP00000024910	99.6078	99.6078
ENSG00000108953	homo_sapiens	ENSP00000264335	83.1373	78.4314	octodon_degus	ENSODEP00000001699	90.9871	85.8369
ENSG00000108953	homo_sapiens	ENSP00000264335	98.8235	98.4314	octodon_degus	ENSODEP00000025567	99.2126	98.8189
ENSG00000108953	homo_sapiens	ENSP00000264335	69.0196	65.098	octodon_degus	ENSODEP00000024773	83.8095	79.0476
ENSG00000108953	homo_sapiens	ENSP00000264335	82.7451	81.5686	octodon_degus	ENSODEP00000001204	95.4751	94.1176
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	jaculus_jaculus	ENSJJAP00000011647	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	70.5882	70.1961	ovis_aries_rambouillet	ENSOARP00020017309	96.7742	96.2366
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	ursus_maritimus	ENSUMAP00000013544	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	47.8431	47.451	ochotona_princeps	ENSOPRP00000012059	53.2751	52.8384
ENSG00000108953	homo_sapiens	ENSP00000264335	95.6863	94.5098	delphinapterus_leucas	ENSDLEP00000010746	94.9416	93.7743
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	physeter_catodon	ENSPCTP00005009965	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mus_caroli	MGP_CAROLIEiJ_P0028303	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mus_musculus	ENSMUSP00000070993	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	99.2157	dipodomys_ordii	ENSDORP00000019901	100	99.2157
ENSG00000108953	homo_sapiens	ENSP00000264335	64.3137	56.4706	mustela_putorius_furo	ENSMPUP00000017338	74.2081	65.1584
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	aotus_nancymaae	ENSANAP00000016902	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	saimiri_boliviensis_boliviensis	ENSSBOP00000039087	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	vicugna_pacos	ENSVPAP00000009571	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	93.3333	chlorocebus_sabaeus	ENSCSAP00000010211	99.1667	99.1667
ENSG00000108953	homo_sapiens	ENSP00000264335	58.8235	58.8235	tupaia_belangeri	ENSTBEP00000014088	64.3777	64.3777
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mesocricetus_auratus	ENSMAUP00000009198	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	phocoena_sinus	ENSPSNP00000030465	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	69.8039	68.6274	camelus_dromedarius	ENSCDRP00005026546	90.8163	89.2857
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	camelus_dromedarius	ENSCDRP00005018243	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	carlito_syrichta	ENSTSYP00000008333	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	90.9804	panthera_tigris_altaica	ENSPTIP00000002282	94.7368	93.9271
ENSG00000108953	homo_sapiens	ENSP00000264335	90.9804	90.9804	panthera_tigris_altaica	ENSPTIP00000009369	90.9804	90.9804
ENSG00000108953	homo_sapiens	ENSP00000264335	96.0784	94.902	rattus_norvegicus	ENSRNOP00000081735	93.5115	92.3664
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.6078	prolemur_simus	ENSPSMP00000020270	99.6078	99.6078
ENSG00000108953	homo_sapiens	ENSP00000264335	42.7451	37.6471	microtus_ochrogaster	ENSMOCP00000018428	90.8333	80
ENSG00000108953	homo_sapiens	ENSP00000264335	98.8235	98.4314	sorex_araneus	ENSSARP00000011730	99.2126	98.8189
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	peromyscus_maniculatus_bairdii	ENSPEMP00000004504	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	bos_mutus	ENSBMUP00000013002	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mus_spicilegus	ENSMSIP00000029110	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	cricetulus_griseus_chok1gshd	ENSCGRP00001007520	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	74.5098	70.1961	cricetulus_griseus_chok1gshd	ENSCGRP00001027724	83.7004	78.8546
ENSG00000108953	homo_sapiens	ENSP00000264335	98.8235	98.4314	pteropus_vampyrus	ENSPVAP00000003463	99.6047	99.2095
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	myotis_lucifugus	ENSMLUP00000001545	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	vombatus_ursinus	ENSVURP00010010822	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	rhinolophus_ferrumequinum	ENSRFEP00010013641	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	neovison_vison	ENSNVIP00000010765	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	95.6863	94.1176	bos_taurus	ENSBTAP00000073185	92.7757	91.2548
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	91.7647	heterocephalus_glaber_female	ENSHGLP00000060207	94.0711	92.4901
ENSG00000108953	homo_sapiens	ENSP00000264335	96.4706	94.1176	heterocephalus_glaber_female	ENSHGLP00000041274	90.4412	88.2353
ENSG00000108953	homo_sapiens	ENSP00000264335	86.6667	86.6667	rhinopithecus_bieti	ENSRBIP00000031228	89.8374	89.8374
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	91.7647	canis_lupus_dingo	ENSCAFP00020012510	88.6364	88.6364
ENSG00000108953	homo_sapiens	ENSP00000264335	33.7255	32.1569	sciurus_vulgaris	ENSSVLP00005015418	90.5263	86.3158
ENSG00000108953	homo_sapiens	ENSP00000264335	52.9412	50.5882	phascolarctos_cinereus	ENSPCIP00000018707	94.4056	90.2098
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	phascolarctos_cinereus	ENSPCIP00000022631	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.6078	procavia_capensis	ENSPCAP00000014791	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	72.9412	69.8039	nannospalax_galili	ENSNGAP00000009841	90.2913	86.4078
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	nannospalax_galili	ENSNGAP00000022033	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	bos_grunniens	ENSBGRP00000022307	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	chinchilla_lanigera	ENSCLAP00000009356	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	48.2353	42.3529	cervus_hanglu_yarkandensis	ENSCHYP00000024506	79.3548	69.6774
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	catagonus_wagneri	ENSCWAP00000002557	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	ictidomys_tridecemlineatus	ENSSTOP00000004563	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	90.9804	90.9804	otolemur_garnettii	ENSOGAP00000005495	99.5708	99.5708
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	93.7255	cebus_imitator	ENSCCAP00000009165	97.5904	95.9839
ENSG00000108953	homo_sapiens	ENSP00000264335	81.5686	81.5686	cebus_imitator	ENSCCAP00000032800	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	urocitellus_parryii	ENSUPAP00010023047	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	moschus_moschiferus	ENSMMSP00000006103	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	rhinopithecus_roxellana	ENSRROP00000032138	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	mus_pahari	MGP_PahariEiJ_P0035046	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.6078	propithecus_coquereli	ENSPCOP00000023402	99.6078	99.6078
ENSG00000108953	homo_sapiens	ENSP00000264335	86.6667	83.5294	petromyzon_marinus	ENSPMAP00000006678	94.0426	90.6383
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	87.8431	petromyzon_marinus	ENSPMAP00000007305	91.8605	86.8217
ENSG00000108953	homo_sapiens	ENSP00000264335	85.8824	76.8627	eptatretus_burgeri	ENSEBUP00000026197	90.4959	80.9917
ENSG00000108953	homo_sapiens	ENSP00000264335	90.5882	89.8039	callorhinchus_milii	ENSCMIP00000030913	87.5	86.7424
ENSG00000108953	homo_sapiens	ENSP00000264335	98.4314	97.6471	lepisosteus_oculatus	ENSLOCP00000008627	88.0702	87.3684
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	94.1176	clupea_harengus	ENSCHAP00000047077	97.2549	94.1176
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	96.4706	danio_rerio	ENSDARP00000032575	97.6471	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	96.4706	carassius_auratus	ENSCARP00000008000	97.6471	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	93.7255	90.1961	carassius_auratus	ENSCARP00000036401	46.2282	44.4874
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	96.0784	astyanax_mexicanus	ENSAMXP00000032615	97.6471	96.0784
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	96.0784	ictalurus_punctatus	ENSIPUP00000008699	97.6471	96.0784
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.4706	esox_lucius	ENSELUP00000032787	97.2549	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	96.8627	96.4706	esox_lucius	ENSELUP00000038325	96.8627	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	95.2941	electrophorus_electricus	ENSEEEP00000052618	97.6471	95.2941
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.2941	oncorhynchus_kisutch	ENSOKIP00005082517	96.4981	94.5525
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	91.3726	oncorhynchus_kisutch	ENSOKIP00005054385	84.6429	83.2143
ENSG00000108953	homo_sapiens	ENSP00000264335	90.1961	89.4118	oncorhynchus_kisutch	ENSOKIP00005022652	88.1226	87.3563
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.6863	oncorhynchus_mykiss	ENSOMYP00000066312	96.875	95.3125
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	89.4118	oncorhynchus_mykiss	ENSOMYP00000099385	95.9514	92.3077
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	91.3726	oncorhynchus_mykiss	ENSOMYP00000003293	84.9462	83.5125
ENSG00000108953	homo_sapiens	ENSP00000264335	90.1961	89.4118	oncorhynchus_mykiss	ENSOMYP00000028065	88.1226	87.3563
ENSG00000108953	homo_sapiens	ENSP00000264335	89.4118	86.6667	salmo_salar	ENSSSAP00000017777	83.5165	80.9524
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.2941	salmo_salar	ENSSSAP00000116140	96.4981	94.5525
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.0784	salmo_salar	ENSSSAP00000063156	96.875	95.7031
ENSG00000108953	homo_sapiens	ENSP00000264335	96.8627	96.4706	salmo_salar	ENSSSAP00000116123	90.8088	90.4412
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.6863	salmo_trutta	ENSSTUP00000037677	96.4981	94.9416
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	92.1569	salmo_trutta	ENSSTUP00000095776	68.4971	67.9191
ENSG00000108953	homo_sapiens	ENSP00000264335	96.4706	96.0784	salmo_trutta	ENSSTUP00000023047	96.0938	95.7031
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.0784	salmo_trutta	ENSSTUP00000015272	96.875	95.7031
ENSG00000108953	homo_sapiens	ENSP00000264335	90.5882	86.2745	gadus_morhua	ENSGMOP00000069231	80.4878	76.6551
ENSG00000108953	homo_sapiens	ENSP00000264335	58.8235	57.2549	fundulus_heteroclitus	ENSFHEP00000020509	89.2857	86.9048
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	90.5882	poecilia_reticulata	ENSPREP00000013775	94.902	90.5882
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	92.549	xiphophorus_maculatus	ENSXMAP00000000534	94.1634	91.8288
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	87.8431	oryzias_latipes	ENSORLP00000012249	68.9349	66.2722
ENSG00000108953	homo_sapiens	ENSP00000264335	92.1569	89.4118	cyclopterus_lumpus	ENSCLMP00005004782	89.6947	87.0229
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	89.0196	oreochromis_niloticus	ENSONIP00000046559	86.3469	83.7638
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.549	haplochromis_burtoni	ENSHBUP00000011074	94.5098	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.549	astatotilapia_calliptera	ENSACLP00000033390	94.5098	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	91.7647	sparus_aurata	ENSSAUP00010029996	94.9219	91.4062
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	89.0196	lates_calcarifer	ENSLCAP00010032368	90.6977	87.9845
ENSG00000108953	homo_sapiens	ENSP00000264335	98.4314	96.4706	xenopus_tropicalis	ENSXETP00000074359	98.4314	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	49.8039	48.6275	chrysemys_picta_bellii	ENSCPBP00000014876	84.6667	82.6667
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	sphenodon_punctatus	ENSSPUP00000009917	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	94.1176	93.7255	crocodylus_porosus	ENSCPRP00005023337	96	95.6
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.2157	laticauda_laticaudata	ENSLLTP00000016355	99.6078	99.2157
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.2157	notechis_scutatus	ENSNSUP00000008121	99.6078	99.2157
ENSG00000108953	homo_sapiens	ENSP00000264335	99.6078	99.2157	pseudonaja_textilis	ENSPTXP00000016834	99.6078	99.2157
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	anas_platyrhynchos_platyrhynchos	ENSAPLP00000007187	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	gallus_gallus	ENSGALP00010043631	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	91.7647	91.7647	meleagris_gallopavo	ENSMGAP00000027038	97.5	97.5
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	serinus_canaria	ENSSCAP00000009106	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	parus_major	ENSPMJP00000026011	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.549	neolamprologus_brichardi	ENSNBRP00000016899	94.5098	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	93.7255	92.549	naja_naja	ENSNNAP00000000724	96.371	95.1613
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	90.9804	podarcis_muralis	ENSPMRP00000033447	100	99.5708
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	geospiza_fortis	ENSGFOP00000005493	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	93.3333	taeniopygia_guttata	ENSTGUP00000005605	99.5816	99.5816
ENSG00000108953	homo_sapiens	ENSP00000264335	98.0392	96.8627	erpetoichthys_calabaricus	ENSECRP00000010933	98.0392	96.8627
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.1569	kryptolebias_marmoratus	ENSKMAP00000012029	94.5525	91.4397
ENSG00000108953	homo_sapiens	ENSP00000264335	100	99.6078	salvator_merianae	ENSSMRP00000009583	100	99.6078
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	91.3726	oryzias_javanicus	ENSOJAP00000004288	72.5904	70.1807
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	92.9412	amphilophus_citrinellus	ENSACIP00000016531	94.902	92.9412
ENSG00000108953	homo_sapiens	ENSP00000264335	90.9804	88.6274	dicentrarchus_labrax	ENSDLAP00005013599	94.3089	91.8699
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.9412	amphiprion_percula	ENSAPEP00000016489	94.5525	92.2179
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	91.7647	oryzias_sinensis	ENSOSIP00000034722	69.8551	67.8261
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	pelodiscus_sinensis	ENSPSIP00000012906	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	gopherus_evgoodei	ENSGEVP00005010200	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	chelonoidis_abingdonii	ENSCABP00000028208	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.9412	seriola_dumerili	ENSSDUP00000030318	95.2941	92.9412
ENSG00000108953	homo_sapiens	ENSP00000264335	89.8039	87.0588	cottoperca_gobio	ENSCGOP00000013974	88.7597	86.0465
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	struthio_camelus_australis	ENSSCUP00000012460	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	anser_brachyrhynchus	ENSABRP00000011425	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	83.5294	76.4706	gasterosteus_aculeatus	ENSGACP00000007178	83.2031	76.1719
ENSG00000108953	homo_sapiens	ENSP00000264335	90.5882	82.3529	cynoglossus_semilaevis	ENSCSEP00000008212	90.9449	82.6772
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	90.5882	poecilia_formosa	ENSPFOP00000000479	93.6759	91.3043
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.1569	poecilia_formosa	ENSPFOP00000015942	73.9264	72.0859
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	91.3726	myripristis_murdjan	ENSMMDP00005034036	94.1634	90.6615
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	89.4118	myripristis_murdjan	ENSMMDP00005036665	90.8046	87.3563
ENSG00000108953	homo_sapiens	ENSP00000264335	92.1569	89.0196	sander_lucioperca	ENSSLUP00000024305	91.4397	88.3269
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	strigops_habroptila	ENSSHBP00005018566	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.9412	amphiprion_ocellaris	ENSAOCP00000027655	94.5525	92.2179
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	terrapene_carolina_triunguis	ENSTMTP00000014785	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	92.1569	hucho_hucho	ENSHHUP00000037862	92.607	91.4397
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.0784	hucho_hucho	ENSHHUP00000071052	87.0175	85.9649
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.0784	hucho_hucho	ENSHHUP00000059998	96.875	95.7031
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	89.0196	betta_splendens	ENSBSLP00000026566	90.4943	86.3118
ENSG00000108953	homo_sapiens	ENSP00000264335	98.0392	96.4706	pygocentrus_nattereri	ENSPNAP00000003169	98.0392	96.4706
ENSG00000108953	homo_sapiens	ENSP00000264335	92.1569	88.6274	anabas_testudineus	ENSATEP00000058340	90.7336	87.2587
ENSG00000108953	homo_sapiens	ENSP00000264335	83.9216	74.1176	saccharomyces_cerevisiae	YDR099W	78.3883	69.2308
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.9412	seriola_lalandi_dorsalis	ENSSLDP00000004548	95.2941	92.9412
ENSG00000108953	homo_sapiens	ENSP00000264335	93.7255	91.3726	labrus_bergylta	ENSLBEP00000032771	93.7255	91.3726
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.549	pundamilia_nyererei	ENSPNYP00000014529	94.5098	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	92.1569	88.2353	mastacembelus_armatus	ENSMAMP00000066509	91.7969	87.8906
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.9412	stegastes_partitus	ENSSPAP00000025576	95.2941	92.9412
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.2941	oncorhynchus_tshawytscha	ENSOTSP00005040677	85.8131	84.083
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	88.2353	oncorhynchus_tshawytscha	ENSOTSP00005041368	89.9614	86.8726
ENSG00000108953	homo_sapiens	ENSP00000264335	92.9412	92.1569	oncorhynchus_tshawytscha	ENSOTSP00005077775	68.6957	68.1159
ENSG00000108953	homo_sapiens	ENSP00000264335	90.1961	89.4118	oncorhynchus_tshawytscha	ENSOTSP00005022099	88.1226	87.3563
ENSG00000108953	homo_sapiens	ENSP00000264335	90.1961	89.4118	oncorhynchus_tshawytscha	ENSOTSP00005100738	88.1226	87.3563
ENSG00000108953	homo_sapiens	ENSP00000264335	46.2745	43.9216	acanthochromis_polyacanthus	ENSAPOP00000033614	92.1875	87.5
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	aquila_chrysaetos_chrysaetos	ENSACCP00020007348	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.549	nothobranchius_furzeri	ENSNFUP00015015518	93.8224	91.1197
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	91.7647	cyprinodon_variegatus	ENSCVAP00000024378	94.902	91.7647
ENSG00000108953	homo_sapiens	ENSP00000264335	93.3333	89.8039	denticeps_clupeoides	ENSDCDP00000031744	92.9688	89.4531
ENSG00000108953	homo_sapiens	ENSP00000264335	95.2941	92.549	larimichthys_crocea	ENSLCRP00005009054	95.2941	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	85.098	takifugu_rubripes	ENSTRUP00000076717	90.6615	84.4358
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	91.3726	ficedula_albicollis	ENSFALP00000021963	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	90.9804	84.3137	hippocampus_comes	ENSHCOP00000007785	90.9804	84.3137
ENSG00000108953	homo_sapiens	ENSP00000264335	90.5882	89.4118	cyprinus_carpio_carpio	ENSCCRP00000054496	96.25	95
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	96.0784	cyprinus_carpio_carpio	ENSCCRP00000049442	97.2549	96.0784
ENSG00000108953	homo_sapiens	ENSP00000264335	100	100	coturnix_japonica	ENSCJPP00005012474	100	100
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	92.549	poecilia_latipinna	ENSPLAP00000030528	74.6914	72.8395
ENSG00000108953	homo_sapiens	ENSP00000264335	94.902	92.549	poecilia_latipinna	ENSPLAP00000017306	94.1634	91.8288
ENSG00000108953	homo_sapiens	ENSP00000264335	37.6471	34.1176	sinocyclocheilus_grahami	ENSSGRP00000059434	78.6885	71.3115
ENSG00000108953	homo_sapiens	ENSP00000264335	94.5098	92.549	maylandia_zebra	ENSMZEP00005014388	94.5098	92.549
ENSG00000108953	homo_sapiens	ENSP00000264335	92.549	86.2745	tetraodon_nigroviridis	ENSTNIP00000004868	92.9134	86.6142
ENSG00000108953	homo_sapiens	ENSP00000264335	91.3726	90.9804	paramormyrops_kingsleyae	ENSPKIP00000003836	97.0833	96.6667
ENSG00000108953	homo_sapiens	ENSP00000264335	97.6471	97.2549	scleropages_formosus	ENSSFOP00015049431	97.6471	97.2549
ENSG00000108953	homo_sapiens	ENSP00000264335	66.2745	62.3529	leptobrachium_leishanense	ENSLLEP00000013516	88.9474	83.6842
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.2941	leptobrachium_leishanense	ENSLLEP00000015921	97.2549	95.2941
ENSG00000108953	homo_sapiens	ENSP00000264335	97.2549	95.2941	leptobrachium_leishanense	ENSLLEP00000010912	97.2549	95.2941
ENSG00000108953	homo_sapiens	ENSP00000264335	75.2941	68.6274	scophthalmus_maximus	ENSSMAP00000041028	73.8462	67.3077
ENSG00000108953	homo_sapiens	ENSP00000264335	90.9804	87.8431	oryzias_melastigma	ENSOMEP00000001350	79.1809	76.4505

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000165	involved_in MAPK cascade	1	IDA	Homo_sapiens(9606)	Process
GO:0001764	involved_in neuron migration	1	IEA	Homo_sapiens(9606)	Process
GO:0003064	involved_in regulation of heart rate by hormone	1	NAS	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005246	enables calcium channel regulator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005886	colocalizes_with plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	HDA	Homo_sapiens(9606)	Component
GO:0006605	involved_in protein targeting	1	IEA	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0007346	involved_in regulation of mitotic cell cycle	1	IBA	Homo_sapiens(9606)	Process
GO:0015459	enables potassium channel regulator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0019903	enables protein phosphatase binding	1	IEA	Homo_sapiens(9606)	Function
GO:0019904	enables protein domain specific binding	1	IEA	Homo_sapiens(9606)	Function
GO:0021762	involved_in substantia nigra development	1	HEP	Homo_sapiens(9606)	Process
GO:0021766	involved_in hippocampus development	1	IEA	Homo_sapiens(9606)	Process
GO:0021987	involved_in cerebral cortex development	1	IEA	Homo_sapiens(9606)	Process
GO:0023026	enables MHC class II protein complex binding	1	HDA	Homo_sapiens(9606)	Function
GO:0031625	enables ubiquitin protein ligase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0034504	involved_in protein localization to nucleus	1	IMP	Homo_sapiens(9606)	Process
GO:0034605	involved_in cellular response to heat	1	IDA	Homo_sapiens(9606)	Process
GO:0035556	involved_in intracellular signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:0042470	located_in melanosome	1	IEA	Homo_sapiens(9606)	Component
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0042826	enables histone deacetylase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0044325	enables transmembrane transporter binding	1	IPI	Homo_sapiens(9606)	Function
GO:0045296	enables cadherin binding	1	HDA	Homo_sapiens(9606)	Function
GO:0046827	involved_in positive regulation of protein export from nucleus	1	IDA	Homo_sapiens(9606)	Process
GO:0046982	enables protein heterodimerization activity	1	IPI	Homo_sapiens(9606)	Function
GO:0050815	enables phosphoserine residue binding	2	IBA,IPI	Homo_sapiens(9606)	Function
GO:0051219	enables phosphoprotein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0051480	involved_in regulation of cytosolic calcium ion concentration	1	IDA	Homo_sapiens(9606)	Process
GO:0060306	involved_in regulation of membrane repolarization	1	IDA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0086013	involved_in membrane repolarization during cardiac muscle cell action potential	1	IC	Homo_sapiens(9606)	Process
GO:0086091	involved_in regulation of heart rate by cardiac conduction	1	IC	Homo_sapiens(9606)	Process
GO:0097110	enables scaffold protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:1901016	involved_in regulation of potassium ion transmembrane transporter activity	1	IDA	Homo_sapiens(9606)	Process
GO:1901020	involved_in negative regulation of calcium ion transmembrane transporter activity	1	IDA	Homo_sapiens(9606)	Process
GO:1902309	involved_in negative regulation of peptidyl-serine dephosphorylation	1	IDA	Homo_sapiens(9606)	Process
GO:1905913	involved_in negative regulation of calcium ion export across plasma membrane	1	IDA	Homo_sapiens(9606)	Process