RBP Type
Canonical_RBPs
Diseases
Cancer
Drug
N.A.
Main interacting RNAs
ncRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000108771 Gene ID
79132
Accession
29517
Symbol
DHX58
Alias
LGP2;RLR-3;D11LGP2;D11lgp2e
Full Name
DExH-box helicase 58
Status
Confidence
Length
11311 bases
Strand
Minus strand
Position
17 : 42101404 - 42112714
RNA binding domain
ResIII , DEAD , RIG-I_C , RIG-I_C-RD
Summary
Enables double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Involved in negative regulation of defense response and negative regulation of type I interferon production. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000416389
DEAD
PF00270
1.5e-15
1
ENSP00000416389
ResIII
PF04851
3.9e-18
2
ENSP00000416389
RIG-I_C
PF18119
7.9e-23
3
ENSP00000251642
DEAD
PF00270
6.6e-15
1
ENSP00000251642
ResIII
PF04851
9.8e-18
2
ENSP00000251642
RIG-I_C-RD
PF11648
1.4e-35
3
ENSP00000251642
RIG-I_C
PF18119
3.7e-31
4
ENSP00000404639
DEAD
PF00270
7.7e-15
1
ENSP00000404639
ResIII
PF04851
1.4e-17
2
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
31623175
Current Understanding of West Nile Virus Clinical Manifestations, Immune Responses, Neuroinvasion, and Immunotherapeutic Implications.
Fengwei Bai
2019-10-16
Pathogens (Basel, Switzerland)
31324030
Integrated Transcriptomic and Proteomic Analysis of Red Blood Cells from Rainbow Trout Challenged with VHSV Point Towards Novel Immunomodulant Targets.
Ivan Nombela
2019-07-09
Vaccines
Name
Transcript ID
bp
Protein
Translation ID
DHX58-205
ENST00000589979
782
51aa
ENSP00000467470
DHX58-201
ENST00000251642
2591
678aa
ENSP00000251642
DHX58-208
ENST00000592024
941
No protein
-
DHX58-204
ENST00000586522
2331
No protein
-
DHX58-206
ENST00000590637
748
No protein
-
DHX58-202
ENST00000413196
1283
302aa
ENSP00000416389
DHX58-207
ENST00000591220
540
99aa
ENSP00000466721
DHX58-203
ENST00000430773
730
156aa
ENSP00000404639
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108771 homo_sapiens ENSP00000497271 40.3902 28.0976 homo_sapiens ENSP00000251642 61.0619 42.4779 ENSG00000108771 homo_sapiens ENSP00000369213 36.8649 22.5946 homo_sapiens ENSP00000251642 50.295 30.826
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108771 homo_sapiens ENSP00000251642 87.4631 85.1032 nomascus_leucogenys ENSNLEP00000024135 92.224 89.7356 ENSG00000108771 homo_sapiens ENSP00000251642 99.41 98.8201 pan_paniscus ENSPPAP00000015998 99.41 98.8201 ENSG00000108771 homo_sapiens ENSP00000251642 98.3776 96.9027 pongo_abelii ENSPPYP00000031676 98.3776 96.9027 ENSG00000108771 homo_sapiens ENSP00000251642 99.41 98.9676 pan_troglodytes ENSPTRP00000015656 99.41 98.9676 ENSG00000108771 homo_sapiens ENSP00000251642 98.9676 98.3776 gorilla_gorilla ENSGGOP00000005347 98.9676 98.3776 ENSG00000108771 homo_sapiens ENSP00000251642 75.0737 60.6195 ornithorhynchus_anatinus ENSOANP00000044306 74.0902 59.8253 ENSG00000108771 homo_sapiens ENSP00000251642 80.531 66.5192 sarcophilus_harrisii ENSSHAP00000007054 80.531 66.5192 ENSG00000108771 homo_sapiens ENSP00000251642 79.4985 66.2242 notamacropus_eugenii ENSMEUP00000005091 80.568 67.1151 ENSG00000108771 homo_sapiens ENSP00000251642 51.7699 46.6077 choloepus_hoffmanni ENSCHOP00000009344 87.3134 78.607 ENSG00000108771 homo_sapiens ENSP00000251642 87.3156 78.1711 dasypus_novemcinctus ENSDNOP00000023964 87.3156 78.1711 ENSG00000108771 homo_sapiens ENSP00000251642 57.3746 51.4749 erinaceus_europaeus ENSEEUP00000002482 57.3746 51.4749 ENSG00000108771 homo_sapiens ENSP00000251642 54.2773 49.705 echinops_telfairi ENSETEP00000015934 54.2773 49.705 ENSG00000108771 homo_sapiens ENSP00000251642 95.1327 90.708 callithrix_jacchus ENSCJAP00000051323 95.1327 90.708 ENSG00000108771 homo_sapiens ENSP00000251642 97.9351 96.1652 cercocebus_atys ENSCATP00000041142 97.9351 96.1652 ENSG00000108771 homo_sapiens ENSP00000251642 97.9351 95.7227 macaca_fascicularis ENSMFAP00000036359 97.076 94.883 ENSG00000108771 homo_sapiens ENSP00000251642 97.9351 95.7227 macaca_mulatta ENSMMUP00000019371 97.9351 95.7227 ENSG00000108771 homo_sapiens ENSP00000251642 97.9351 95.8702 macaca_nemestrina ENSMNEP00000042534 97.9351 95.8702 ENSG00000108771 homo_sapiens ENSP00000251642 98.0826 96.1652 papio_anubis ENSPANP00000045844 98.0826 96.1652 ENSG00000108771 homo_sapiens ENSP00000251642 98.0826 96.1652 mandrillus_leucophaeus ENSMLEP00000037005 98.0826 96.1652 ENSG00000108771 homo_sapiens ENSP00000251642 90.708 82.7434 tursiops_truncatus ENSTTRP00000006295 90.5744 82.6215 ENSG00000108771 homo_sapiens ENSP00000251642 87.7581 80.531 vulpes_vulpes ENSVVUP00000028896 77.0725 70.7254 ENSG00000108771 homo_sapiens ENSP00000251642 87.6106 78.9086 mus_spretus MGP_SPRETEiJ_P0031323 87.6106 78.9086 ENSG00000108771 homo_sapiens ENSP00000251642 91.1504 84.2183 equus_asinus ENSEASP00005013056 91.2851 84.3427 ENSG00000108771 homo_sapiens ENSP00000251642 88.3481 81.2684 capra_hircus ENSCHIP00000016966 87.4453 80.438 ENSG00000108771 homo_sapiens ENSP00000251642 89.233 82.1534 loxodonta_africana ENSLAFP00000022333 88.5798 81.552 ENSG00000108771 homo_sapiens ENSP00000251642 90.8555 84.2183 panthera_leo ENSPLOP00000009049 89.927 83.3577 ENSG00000108771 homo_sapiens ENSP00000251642 89.3805 82.3009 ailuropoda_melanoleuca ENSAMEP00000006268 90.4478 83.2836 ENSG00000108771 homo_sapiens ENSP00000251642 86.7257 78.0236 bos_indicus_hybrid ENSBIXP00005046804 82.0084 73.7796 ENSG00000108771 homo_sapiens ENSP00000251642 89.6755 83.1858 oryctolagus_cuniculus ENSOCUP00000011424 80.4233 74.6032 ENSG00000108771 homo_sapiens ENSP00000251642 91.4454 84.6608 canis_lupus_familiaris ENSCAFP00845014250 91.4454 84.6608 ENSG00000108771 homo_sapiens ENSP00000251642 90.8555 84.3658 panthera_pardus ENSPPRP00000010924 89.927 83.5036 ENSG00000108771 homo_sapiens ENSP00000251642 92.1829 84.5133 marmota_marmota_marmota ENSMMMP00000006880 92.1829 84.5133 ENSG00000108771 homo_sapiens ENSP00000251642 91.5929 83.9233 balaenoptera_musculus ENSBMSP00010026475 91.1894 83.5536 ENSG00000108771 homo_sapiens ENSP00000251642 88.7906 81.4159 cavia_porcellus ENSCPOP00000014777 88.7906 81.4159 ENSG00000108771 homo_sapiens ENSP00000251642 91.1504 84.3658 felis_catus ENSFCAP00000001983 90.219 83.5036 ENSG00000108771 homo_sapiens ENSP00000251642 90.2655 82.5959 ursus_americanus ENSUAMP00000032004 90.8012 83.0861 ENSG00000108771 homo_sapiens ENSP00000251642 80.0885 66.8142 monodelphis_domestica ENSMODP00000018488 78.8099 65.7475 ENSG00000108771 homo_sapiens ENSP00000251642 91.1504 83.1858 bison_bison_bison ENSBBBP00000001402 90.8824 82.9412 ENSG00000108771 homo_sapiens ENSP00000251642 90.5605 82.7434 monodon_monoceros ENSMMNP00015024685 90.2941 82.5 ENSG00000108771 homo_sapiens ENSP00000251642 90.2655 82.7434 sus_scrofa ENSSSCP00000018455 89.8678 82.3789 ENSG00000108771 homo_sapiens ENSP00000251642 93.2153 86.4307 microcebus_murinus ENSMICP00000050539 93.2153 86.4307 ENSG00000108771 homo_sapiens ENSP00000251642 87.3156 80.236 octodon_degus ENSODEP00000024455 87.3156 80.236 ENSG00000108771 homo_sapiens ENSP00000251642 88.0531 79.4985 jaculus_jaculus ENSJJAP00000001002 88.0531 79.4985 ENSG00000108771 homo_sapiens ENSP00000251642 90.2655 83.1858 ovis_aries_rambouillet ENSOARP00020004062 90 82.9412 ENSG00000108771 homo_sapiens ENSP00000251642 90.708 82.4484 ursus_maritimus ENSUMAP00000031895 85.1801 77.4238 ENSG00000108771 homo_sapiens ENSP00000251642 87.4631 78.7611 ochotona_princeps ENSOPRP00000000684 87.4631 78.7611 ENSG00000108771 homo_sapiens ENSP00000251642 80.9734 72.7139 delphinapterus_leucas ENSDLEP00000012684 76.0388 68.2825 ENSG00000108771 homo_sapiens ENSP00000251642 91.7404 83.1858 physeter_catodon ENSPCTP00005029368 91.3363 82.8194 ENSG00000108771 homo_sapiens ENSP00000251642 87.1681 78.9086 mus_caroli MGP_CAROLIEiJ_P0029903 87.1681 78.9086 ENSG00000108771 homo_sapiens ENSP00000251642 87.4631 78.6136 mus_musculus ENSMUSP00000017974 87.4631 78.6136 ENSG00000108771 homo_sapiens ENSP00000251642 90.413 82.4484 dipodomys_ordii ENSDORP00000006386 90.413 82.4484 ENSG00000108771 homo_sapiens ENSP00000251642 90.118 82.8909 mustela_putorius_furo ENSMPUP00000010490 89.9853 82.7688 ENSG00000108771 homo_sapiens ENSP00000251642 95.7227 91.003 aotus_nancymaae ENSANAP00000022610 95.7227 91.003 ENSG00000108771 homo_sapiens ENSP00000251642 95.4277 91.003 saimiri_boliviensis_boliviensis ENSSBOP00000007266 95.4277 91.003 ENSG00000108771 homo_sapiens ENSP00000251642 43.3628 39.6755 vicugna_pacos ENSVPAP00000005059 50.0852 45.8262 ENSG00000108771 homo_sapiens ENSP00000251642 97.4926 94.9853 chlorocebus_sabaeus ENSCSAP00000014957 97.4926 94.9853 ENSG00000108771 homo_sapiens ENSP00000251642 72.4189 65.7817 tupaia_belangeri ENSTBEP00000004677 72.3122 65.6848 ENSG00000108771 homo_sapiens ENSP00000251642 89.233 81.1209 mesocricetus_auratus ENSMAUP00000022537 89.233 81.1209 ENSG00000108771 homo_sapiens ENSP00000251642 90.118 81.8584 phocoena_sinus ENSPSNP00000021496 89.8529 81.6176 ENSG00000108771 homo_sapiens ENSP00000251642 91.1504 84.2183 camelus_dromedarius ENSCDRP00005006094 90.7489 83.8473 ENSG00000108771 homo_sapiens ENSP00000251642 52.3599 46.6077 carlito_syrichta ENSTSYP00000015763 91.4948 81.4433 ENSG00000108771 homo_sapiens ENSP00000251642 91.1504 84.6608 panthera_tigris_altaica ENSPTIP00000005901 90.219 83.7956 ENSG00000108771 homo_sapiens ENSP00000251642 87.7581 79.2035 rattus_norvegicus ENSRNOP00000024718 87.7581 79.2035 ENSG00000108771 homo_sapiens ENSP00000251642 91.2979 84.8083 prolemur_simus ENSPSMP00000017801 93.0827 86.4662 ENSG00000108771 homo_sapiens ENSP00000251642 89.3805 80.531 microtus_ochrogaster ENSMOCP00000021842 89.3805 80.531 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 59.7345 sorex_araneus ENSSARP00000002003 66.0714 60.2679 ENSG00000108771 homo_sapiens ENSP00000251642 88.3481 79.2035 peromyscus_maniculatus_bairdii ENSPEMP00000020864 88.3481 79.2035 ENSG00000108771 homo_sapiens ENSP00000251642 91.2979 83.3333 bos_mutus ENSBMUP00000022183 91.0294 83.0882 ENSG00000108771 homo_sapiens ENSP00000251642 87.6106 78.9086 mus_spicilegus ENSMSIP00000005034 87.6106 78.9086 ENSG00000108771 homo_sapiens ENSP00000251642 87.1681 78.9086 cricetulus_griseus_chok1gshd ENSCGRP00001007984 87.0398 78.7923 ENSG00000108771 homo_sapiens ENSP00000251642 90.708 83.0383 pteropus_vampyrus ENSPVAP00000003647 90.5744 82.9161 ENSG00000108771 homo_sapiens ENSP00000251642 91.4454 83.3333 myotis_lucifugus ENSMLUP00000010933 91.0426 82.9662 ENSG00000108771 homo_sapiens ENSP00000251642 80.236 67.1091 vombatus_ursinus ENSVURP00010028673 80.5926 67.4074 ENSG00000108771 homo_sapiens ENSP00000251642 88.938 81.8584 rhinolophus_ferrumequinum ENSRFEP00010010892 91.3636 84.0909 ENSG00000108771 homo_sapiens ENSP00000251642 88.3481 81.4159 neovison_vison ENSNVIP00000015456 88.218 81.296 ENSG00000108771 homo_sapiens ENSP00000251642 86.7257 78.0236 bos_taurus ENSBTAP00000053909 82.0084 73.7796 ENSG00000108771 homo_sapiens ENSP00000251642 88.4956 81.2684 heterocephalus_glaber_female ENSHGLP00000016115 88.6263 81.3885 ENSG00000108771 homo_sapiens ENSP00000251642 98.0826 95.7227 rhinopithecus_bieti ENSRBIP00000010079 98.0826 95.7227 ENSG00000108771 homo_sapiens ENSP00000251642 91.4454 84.6608 canis_lupus_dingo ENSCAFP00020017333 91.1765 84.4118 ENSG00000108771 homo_sapiens ENSP00000251642 92.4779 85.6932 sciurus_vulgaris ENSSVLP00005000370 92.4779 85.6932 ENSG00000108771 homo_sapiens ENSP00000251642 80.531 67.6991 phascolarctos_cinereus ENSPCIP00000027052 80.8889 68 ENSG00000108771 homo_sapiens ENSP00000251642 70.7965 65.1917 procavia_capensis ENSPCAP00000015209 77.7958 71.637 ENSG00000108771 homo_sapiens ENSP00000251642 87.6106 78.9086 nannospalax_galili ENSNGAP00000016349 87.6106 78.9086 ENSG00000108771 homo_sapiens ENSP00000251642 86.5782 77.5811 bos_grunniens ENSBGRP00000019775 81.8689 73.3612 ENSG00000108771 homo_sapiens ENSP00000251642 88.3481 81.4159 chinchilla_lanigera ENSCLAP00000020380 88.3481 81.4159 ENSG00000108771 homo_sapiens ENSP00000251642 90.708 82.1534 cervus_hanglu_yarkandensis ENSCHYP00000013083 90.4412 81.9118 ENSG00000108771 homo_sapiens ENSP00000251642 89.528 81.8584 catagonus_wagneri ENSCWAP00000018047 89.1336 81.4978 ENSG00000108771 homo_sapiens ENSP00000251642 92.1829 84.0708 ictidomys_tridecemlineatus ENSSTOP00000005836 92.1829 84.0708 ENSG00000108771 homo_sapiens ENSP00000251642 92.0354 85.5457 otolemur_garnettii ENSOGAP00000019841 92.0354 85.5457 ENSG00000108771 homo_sapiens ENSP00000251642 95.2802 90.2655 cebus_imitator ENSCCAP00000009608 95.2802 90.2655 ENSG00000108771 homo_sapiens ENSP00000251642 92.1829 84.5133 urocitellus_parryii ENSUPAP00010011691 92.1829 84.5133 ENSG00000108771 homo_sapiens ENSP00000251642 90.2655 82.5959 moschus_moschiferus ENSMMSP00000020566 90 82.3529 ENSG00000108771 homo_sapiens ENSP00000251642 91.8879 88.4956 rhinopithecus_roxellana ENSRROP00000024154 95.8462 92.3077 ENSG00000108771 homo_sapiens ENSP00000251642 87.1681 77.8761 mus_pahari MGP_PahariEiJ_P0036629 87.1681 77.8761 ENSG00000108771 homo_sapiens ENSP00000251642 91.8879 85.2507 propithecus_coquereli ENSPCOP00000019131 91.8879 85.2507 ENSG00000108771 homo_sapiens ENSP00000251642 44.9853 25.0737 caenorhabditis_elegans D2005.5.1 27.2565 15.1921 ENSG00000108771 homo_sapiens ENSP00000251642 42.4779 23.7463 caenorhabditis_elegans F15B10.2a.1 27.7724 15.5256 ENSG00000108771 homo_sapiens ENSP00000251642 16.2242 8.84956 ciona_intestinalis ENSCINP00000023858 26.8293 14.6341 ENSG00000108771 homo_sapiens ENSP00000251642 61.2094 42.6254 eptatretus_burgeri ENSEBUP00000011757 52.1357 36.3065 ENSG00000108771 homo_sapiens ENSP00000251642 70.059 51.6224 callorhinchus_milii ENSCMIP00000007195 70.059 51.6224 ENSG00000108771 homo_sapiens ENSP00000251642 66.5192 47.3451 latimeria_chalumnae ENSLACP00000012725 66.3235 47.2059 ENSG00000108771 homo_sapiens ENSP00000251642 67.6991 51.1799 lepisosteus_oculatus ENSLOCP00000015492 67.1053 50.731 ENSG00000108771 homo_sapiens ENSP00000251642 41.8879 31.2684 clupea_harengus ENSCHAP00000002045 64.3991 48.0726 ENSG00000108771 homo_sapiens ENSP00000251642 66.3717 47.7876 danio_rerio ENSDARP00000110039 66.2739 47.7172 ENSG00000108771 homo_sapiens ENSP00000251642 66.6667 49.5575 carassius_auratus ENSCARP00000047845 64.4793 47.9315 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 47.9351 carassius_auratus ENSCARP00000012461 61.9247 45.3278 ENSG00000108771 homo_sapiens ENSP00000251642 67.6991 50.1475 astyanax_mexicanus ENSAMXP00000042610 66.8122 49.4905 ENSG00000108771 homo_sapiens ENSP00000251642 65.0443 48.2301 ictalurus_punctatus ENSIPUP00000029495 65.1403 48.3013 ENSG00000108771 homo_sapiens ENSP00000251642 64.6018 46.1652 esox_lucius ENSELUP00000019028 64.4118 46.0294 ENSG00000108771 homo_sapiens ENSP00000251642 64.6018 46.1652 electrophorus_electricus ENSEEEP00000016761 65.0817 46.5082 ENSG00000108771 homo_sapiens ENSP00000251642 64.1593 46.1652 oncorhynchus_kisutch ENSOKIP00005104942 65.71 47.281 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 47.6401 oncorhynchus_kisutch ENSOKIP00005080588 64.2442 46.9477 ENSG00000108771 homo_sapiens ENSP00000251642 56.1947 41.0029 oncorhynchus_mykiss ENSOMYP00000143151 64.5763 47.1186 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 48.2301 oncorhynchus_mykiss ENSOMYP00000018640 63.7016 46.9154 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 48.2301 salmo_salar ENSSSAP00000006715 65.4867 48.2301 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 48.2301 salmo_salar ENSSSAP00000029597 65.1026 47.9472 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 47.9351 salmo_trutta ENSSTUP00000088068 64.8094 47.654 ENSG00000108771 homo_sapiens ENSP00000251642 65.3392 48.0826 salmo_trutta ENSSTUP00000046160 64.956 47.8006 ENSG00000108771 homo_sapiens ENSP00000251642 64.1593 44.8378 gadus_morhua ENSGMOP00000055725 64.636 45.1709 ENSG00000108771 homo_sapiens ENSP00000251642 67.2566 48.3776 fundulus_heteroclitus ENSFHEP00000010836 66.9604 48.1645 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 47.9351 poecilia_reticulata ENSPREP00000015488 67.1072 47.7239 ENSG00000108771 homo_sapiens ENSP00000251642 67.6991 48.2301 xiphophorus_maculatus ENSXMAP00000008929 67.4009 48.0176 ENSG00000108771 homo_sapiens ENSP00000251642 66.0767 48.0826 oryzias_latipes ENSORLP00000004757 61.2859 44.5964 ENSG00000108771 homo_sapiens ENSP00000251642 64.8968 46.7552 cyclopterus_lumpus ENSCLMP00005032208 64.7059 46.6176 ENSG00000108771 homo_sapiens ENSP00000251642 62.9794 45.5752 oreochromis_niloticus ENSONIP00000051536 59.8878 43.338 ENSG00000108771 homo_sapiens ENSP00000251642 64.7493 46.3127 haplochromis_burtoni ENSHBUP00000021958 64.6539 46.2445 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 47.7876 haplochromis_burtoni ENSHBUP00000000769 67.3049 47.7172 ENSG00000108771 homo_sapiens ENSP00000251642 65.3392 46.4602 astatotilapia_calliptera ENSACLP00000003814 65.4357 46.5288 ENSG00000108771 homo_sapiens ENSP00000251642 67.2566 47.4926 astatotilapia_calliptera ENSACLP00000003839 67.1576 47.4227 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.7876 sparus_aurata ENSSAUP00010053079 63.0465 45.6982 ENSG00000108771 homo_sapiens ENSP00000251642 65.6342 48.5251 lates_calcarifer ENSLCAP00010015962 65.2493 48.2405 ENSG00000108771 homo_sapiens ENSP00000251642 67.6991 51.6224 xenopus_tropicalis ENSXETP00000064786 67.3021 51.3196 ENSG00000108771 homo_sapiens ENSP00000251642 67.1091 52.6549 chrysemys_picta_bellii ENSCPBP00000008773 61.9891 48.6376 ENSG00000108771 homo_sapiens ENSP00000251642 69.174 53.6873 sphenodon_punctatus ENSSPUP00000016894 69.2762 53.7666 ENSG00000108771 homo_sapiens ENSP00000251642 70.2065 54.4248 crocodylus_porosus ENSCPRP00005007638 70.7281 54.8291 ENSG00000108771 homo_sapiens ENSP00000251642 36.8732 27.1386 laticauda_laticaudata ENSLLTP00000016121 67.0241 49.3298 ENSG00000108771 homo_sapiens ENSP00000251642 33.0383 23.7463 laticauda_laticaudata ENSLLTP00000023642 57.289 41.1765 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 50.1475 notechis_scutatus ENSNSUP00000019018 67.2059 50 ENSG00000108771 homo_sapiens ENSP00000251642 67.2566 50.1475 pseudonaja_textilis ENSPTXP00000009963 67.7563 50.5201 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 50.295 anas_platyrhynchos_platyrhynchos ENSAPLP00000012991 41.3858 31.9288 ENSG00000108771 homo_sapiens ENSP00000251642 67.9941 52.8024 gallus_gallus ENSGALP00010034227 66.6185 51.7341 ENSG00000108771 homo_sapiens ENSP00000251642 62.0944 47.7876 meleagris_gallopavo ENSMGAP00000006824 67.5762 52.0064 ENSG00000108771 homo_sapiens ENSP00000251642 64.6018 50.295 parus_major ENSPMJP00000001323 59.1892 46.0811 ENSG00000108771 homo_sapiens ENSP00000251642 69.3215 54.4248 anolis_carolinensis ENSACAP00000012358 69.1176 54.2647 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 47.1976 neolamprologus_brichardi ENSNBRP00000024153 66.7158 47.1281 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 46.3127 neolamprologus_brichardi ENSNBRP00000024582 65.0957 46.2445 ENSG00000108771 homo_sapiens ENSP00000251642 67.1091 49.705 naja_naja ENSNNAP00000017995 67.6077 50.0743 ENSG00000108771 homo_sapiens ENSP00000251642 68.7316 52.5074 podarcis_muralis ENSPMRP00000021276 68.4288 52.2761 ENSG00000108771 homo_sapiens ENSP00000251642 64.7493 50.885 taeniopygia_guttata ENSTGUP00000024602 56.5722 44.4588 ENSG00000108771 homo_sapiens ENSP00000251642 67.8466 50.295 erpetoichthys_calabaricus ENSECRP00000033723 67.7467 50.2209 ENSG00000108771 homo_sapiens ENSP00000251642 66.0767 46.7552 kryptolebias_marmoratus ENSKMAP00000027099 65.7856 46.5492 ENSG00000108771 homo_sapiens ENSP00000251642 68.7316 52.8024 salvator_merianae ENSSMRP00000020799 68.6303 52.7246 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.0501 oryzias_javanicus ENSOJAP00000032249 63.5846 45.377 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 47.7876 amphilophus_citrinellus ENSACIP00000013700 65 47.6471 ENSG00000108771 homo_sapiens ENSP00000251642 39.0855 25.2212 amphilophus_citrinellus ENSACIP00000013910 59.8194 38.6005 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.6401 dicentrarchus_labrax ENSDLAP00005048423 65.8321 47.57 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.3451 amphiprion_percula ENSAPEP00000006719 65.6388 47.1366 ENSG00000108771 homo_sapiens ENSP00000251642 66.0767 47.9351 oryzias_sinensis ENSOSIP00000001086 65.7856 47.7239 ENSG00000108771 homo_sapiens ENSP00000251642 66.2242 51.1799 pelodiscus_sinensis ENSPSIP00000018695 67.0149 51.791 ENSG00000108771 homo_sapiens ENSP00000251642 71.2389 54.5723 gopherus_evgoodei ENSGEVP00005014393 71.5556 54.8148 ENSG00000108771 homo_sapiens ENSP00000251642 70.7965 54.4248 chelonoidis_abingdonii ENSCABP00000019914 71.1111 54.6667 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 49.2625 seriola_dumerili ENSSDUP00000031986 66.5198 49.0455 ENSG00000108771 homo_sapiens ENSP00000251642 65.6342 47.4926 cottoperca_gobio ENSCGOP00000038941 65.3451 47.2834 ENSG00000108771 homo_sapiens ENSP00000251642 69.6165 54.1298 struthio_camelus_australis ENSSCUP00000018698 70.0297 54.451 ENSG00000108771 homo_sapiens ENSP00000251642 68.2891 53.2448 anser_brachyrhynchus ENSABRP00000010602 68.5926 53.4815 ENSG00000108771 homo_sapiens ENSP00000251642 67.6991 47.6401 gasterosteus_aculeatus ENSGACP00000011552 67.4009 47.4302 ENSG00000108771 homo_sapiens ENSP00000251642 64.8968 46.0177 cynoglossus_semilaevis ENSCSEP00000033316 65.0888 46.1538 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 47.6401 poecilia_formosa ENSPFOP00000011841 66.5198 47.4302 ENSG00000108771 homo_sapiens ENSP00000251642 65.7817 47.9351 myripristis_murdjan ENSMMDP00005019625 65.4919 47.7239 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 48.8201 sander_lucioperca ENSSLUP00000021226 67.2059 48.6765 ENSG00000108771 homo_sapiens ENSP00000251642 69.0266 52.2124 strigops_habroptila ENSSHBP00005013682 69.4362 52.5223 ENSG00000108771 homo_sapiens ENSP00000251642 66.0767 47.3451 amphiprion_ocellaris ENSAOCP00000012297 65.7856 47.1366 ENSG00000108771 homo_sapiens ENSP00000251642 70.354 55.0147 terrapene_carolina_triunguis ENSTMTP00000007798 68.3381 53.4384 ENSG00000108771 homo_sapiens ENSP00000251642 66.0767 48.3776 hucho_hucho ENSHHUP00000037311 66.0767 48.3776 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 47.9351 hucho_hucho ENSHHUP00000085546 65.4867 47.9351 ENSG00000108771 homo_sapiens ENSP00000251642 62.9794 45.7227 betta_splendens ENSBSLP00000011523 58.8154 42.6997 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 49.5575 pygocentrus_nattereri ENSPNAP00000037195 67.0118 49.7041 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.9351 anabas_testudineus ENSATEP00000002565 62.1697 45.2017 ENSG00000108771 homo_sapiens ENSP00000251642 9.73451 6.0472 ciona_savignyi ENSCSAVP00000018923 34.1969 21.2435 ENSG00000108771 homo_sapiens ENSP00000251642 6.0472 3.09735 saccharomyces_cerevisiae YHR218W-A 39.0476 20 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.8466 saccharomyces_cerevisiae YOR396W 14.1425 6.73719 ENSG00000108771 homo_sapiens ENSP00000251642 13.2743 7.07965 saccharomyces_cerevisiae YHL050C 12.9125 6.88666 ENSG00000108771 homo_sapiens ENSP00000251642 21.0914 10.767 saccharomyces_cerevisiae YPR204W 13.8566 7.07364 ENSG00000108771 homo_sapiens ENSP00000251642 26.6962 13.1268 saccharomyces_cerevisiae YLL066C 15.0207 7.38589 ENSG00000108771 homo_sapiens ENSP00000251642 17.9941 8.25959 saccharomyces_cerevisiae YHR218W 20.2322 9.2869 ENSG00000108771 homo_sapiens ENSP00000251642 37.3156 17.9941 saccharomyces_cerevisiae YJL225C 14.3914 6.9397 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.9941 saccharomyces_cerevisiae YNL339C 13.6633 6.56267 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.8466 saccharomyces_cerevisiae YLR467W 14.1425 6.73719 ENSG00000108771 homo_sapiens ENSP00000251642 9.43953 4.71976 saccharomyces_cerevisiae YBL113C 8.08081 4.0404 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.8466 saccharomyces_cerevisiae YDR545W 14.1425 6.73719 ENSG00000108771 homo_sapiens ENSP00000251642 37.3156 17.9941 saccharomyces_cerevisiae YIL177C 14.3914 6.9397 ENSG00000108771 homo_sapiens ENSP00000251642 7.66962 3.53982 saccharomyces_cerevisiae YPR202W 21.8487 10.084 ENSG00000108771 homo_sapiens ENSP00000251642 12.0944 6.34218 saccharomyces_cerevisiae YFL066C 20.9184 10.9694 ENSG00000108771 homo_sapiens ENSP00000251642 5.8997 2.80236 saccharomyces_cerevisiae YEL075C 32.7869 15.5738 ENSG00000108771 homo_sapiens ENSP00000251642 25.3687 12.2419 saccharomyces_cerevisiae YEL077C 13.4691 6.49961 ENSG00000108771 homo_sapiens ENSP00000251642 31.7109 15.0442 saccharomyces_cerevisiae YER190W 12.79 6.06782 ENSG00000108771 homo_sapiens ENSP00000251642 8.70206 4.27729 saccharomyces_cerevisiae YLR462W 29.2079 14.3564 ENSG00000108771 homo_sapiens ENSP00000251642 6.0472 3.09735 saccharomyces_cerevisiae YBL112C 39.0476 20 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.9941 saccharomyces_cerevisiae YPL283C 13.6633 6.56267 ENSG00000108771 homo_sapiens ENSP00000251642 10.472 5.16224 saccharomyces_cerevisiae YHL049C 26.1993 12.9151 ENSG00000108771 homo_sapiens ENSP00000251642 34.5133 16.8142 saccharomyces_cerevisiae YML133C 17.0306 8.29694 ENSG00000108771 homo_sapiens ENSP00000251642 9.29204 4.71976 saccharomyces_cerevisiae YHR219W 10.0962 5.12821 ENSG00000108771 homo_sapiens ENSP00000251642 37.4631 17.9941 saccharomyces_cerevisiae YGR296W 13.6633 6.56267 ENSG00000108771 homo_sapiens ENSP00000251642 26.6962 13.1268 saccharomyces_cerevisiae YLL067C 15.0207 7.38589 ENSG00000108771 homo_sapiens ENSP00000251642 26.4012 12.5369 saccharomyces_cerevisiae YLR466W 12.9522 6.15051 ENSG00000108771 homo_sapiens ENSP00000251642 5.8997 2.65487 saccharomyces_cerevisiae YER189W 32.7869 14.7541 ENSG00000108771 homo_sapiens ENSP00000251642 20.649 9.88201 saccharomyces_cerevisiae YBL111C 20.9895 10.045 ENSG00000108771 homo_sapiens ENSP00000251642 7.66962 3.53982 saccharomyces_cerevisiae YFL064C 29.8851 13.7931 ENSG00000108771 homo_sapiens ENSP00000251642 66.5192 48.5251 seriola_lalandi_dorsalis ENSSLDP00000022645 66.2261 48.3113 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 48.0826 labrus_bergylta ENSLBEP00000005499 67.3049 48.0118 ENSG00000108771 homo_sapiens ENSP00000251642 58.8496 42.1829 pundamilia_nyererei ENSPNYP00000014122 68.0887 48.8055 ENSG00000108771 homo_sapiens ENSP00000251642 65.3392 46.0177 pundamilia_nyererei ENSPNYP00000014627 65.4357 46.0857 ENSG00000108771 homo_sapiens ENSP00000251642 66.6667 48.0826 mastacembelus_armatus ENSMAMP00000046316 65.8892 47.5219 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.9351 stegastes_partitus ENSSPAP00000008534 65.6388 47.7239 ENSG00000108771 homo_sapiens ENSP00000251642 66.2242 48.3776 acanthochromis_polyacanthus ENSAPOP00000030456 65.9324 48.1645 ENSG00000108771 homo_sapiens ENSP00000251642 69.3215 54.1298 aquila_chrysaetos_chrysaetos ENSACCP00020002945 69.8366 54.5319 ENSG00000108771 homo_sapiens ENSP00000251642 66.2242 46.6077 nothobranchius_furzeri ENSNFUP00015011726 67.2156 47.3054 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 47.3451 cyprinodon_variegatus ENSCVAP00000007817 65.6388 47.1366 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 48.5251 denticeps_clupeoides ENSDCDP00000006812 65.3903 48.4536 ENSG00000108771 homo_sapiens ENSP00000251642 64.8968 47.3451 larimichthys_crocea ENSLCRP00005002382 61.3668 44.7699 ENSG00000108771 homo_sapiens ENSP00000251642 64.7493 47.6401 takifugu_rubripes ENSTRUP00000083052 64.1813 47.2222 ENSG00000108771 homo_sapiens ENSP00000251642 64.0118 47.6401 ficedula_albicollis ENSFALP00000022665 67.1827 50 ENSG00000108771 homo_sapiens ENSP00000251642 63.7168 46.4602 hippocampus_comes ENSHCOP00000019409 64.1902 46.8053 ENSG00000108771 homo_sapiens ENSP00000251642 65.6342 47.9351 cyprinus_carpio_carpio ENSCCRP00000109419 64.5864 47.1698 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 48.8201 cyprinus_carpio_carpio ENSCCRP00000112015 67.0118 48.9645 ENSG00000108771 homo_sapiens ENSP00000251642 62.9794 45.5752 cyprinus_carpio_carpio ENSCCRP00000131344 63.8266 46.1883 ENSG00000108771 homo_sapiens ENSP00000251642 62.8319 46.3127 cyprinus_carpio_carpio ENSCCRP00000122666 65.9443 48.6068 ENSG00000108771 homo_sapiens ENSP00000251642 62.5369 47.7876 coturnix_japonica ENSCJPP00005005003 61.3603 46.8886 ENSG00000108771 homo_sapiens ENSP00000251642 66.8142 47.6401 poecilia_latipinna ENSPLAP00000016822 66.5198 47.4302 ENSG00000108771 homo_sapiens ENSP00000251642 28.3186 21.9764 sinocyclocheilus_grahami ENSSGRP00000006916 69.5652 53.9855 ENSG00000108771 homo_sapiens ENSP00000251642 35.6932 24.7788 sinocyclocheilus_grahami ENSSGRP00000002843 41.9411 29.1161 ENSG00000108771 homo_sapiens ENSP00000251642 43.6578 31.2684 sinocyclocheilus_grahami ENSSGRP00000086255 64.6288 46.2882 ENSG00000108771 homo_sapiens ENSP00000251642 65.1917 46.3127 maylandia_zebra ENSMZEP00005030520 65.288 46.3811 ENSG00000108771 homo_sapiens ENSP00000251642 67.4041 47.7876 maylandia_zebra ENSMZEP00005030518 67.3049 47.7172 ENSG00000108771 homo_sapiens ENSP00000251642 65.6342 48.0826 tetraodon_nigroviridis ENSTNIP00000014664 65.4412 47.9412 ENSG00000108771 homo_sapiens ENSP00000251642 64.8968 47.3451 paramormyrops_kingsleyae ENSPKIP00000002172 64.9926 47.4151 ENSG00000108771 homo_sapiens ENSP00000251642 65.4867 49.705 scleropages_formosus ENSSFOP00015036353 64.723 49.1254 ENSG00000108771 homo_sapiens ENSP00000251642 62.9794 44.8378 leptobrachium_leishanense ENSLLEP00000041315 65.9969 46.9861 ENSG00000108771 homo_sapiens ENSP00000251642 65.9292 48.3776 scophthalmus_maximus ENSSMAP00000045742 65.7353 48.2353 ENSG00000108771 homo_sapiens ENSP00000251642 50.7375 37.1681 oryzias_melastigma ENSOMEP00000035647 65.9004 48.2759 ENSG00000108771 homo_sapiens ENSP00000251642 63.7168 45.7227 oryzias_melastigma ENSOMEP00000021158 66.2577 47.546
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0002753 involved_in cytosolic pattern recognition receptor signaling pathway 1 IMP Homo_sapiens(9606) Process GO:0003677 enables DNA binding 1 IEA Homo_sapiens(9606) Function GO:0003724 enables RNA helicase activity 1 IMP Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0003727 enables single-stranded RNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005737 is_active_in cytoplasm 1 IBA Homo_sapiens(9606) Component GO:0008270 enables zinc ion binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0009615 involved_in response to virus 1 ISS Homo_sapiens(9606) Process GO:0009617 involved_in response to bacterium 1 IEA Homo_sapiens(9606) Process GO:0016887 enables ATP hydrolysis activity 1 IMP Homo_sapiens(9606) Function GO:0032480 involved_in negative regulation of type I interferon production 1 IDA Homo_sapiens(9606) Process GO:0032481 involved_in positive regulation of type I interferon production 1 ISS Homo_sapiens(9606) Process GO:0039534 involved_in negative regulation of MDA-5 signaling pathway 1 IMP Homo_sapiens(9606) Process GO:0039536 involved_in negative regulation of RIG-I signaling pathway 3 IBA,IDA,IMP Homo_sapiens(9606) Process GO:0045088 involved_in regulation of innate immune response 1 IDA Homo_sapiens(9606) Process GO:0045824 involved_in negative regulation of innate immune response 1 IDA Homo_sapiens(9606) Process GO:0140374 involved_in antiviral innate immune response 1 IBA Homo_sapiens(9606) Process GO:1900245 involved_in positive regulation of MDA-5 signaling pathway 1 ISS Homo_sapiens(9606) Process GO:1900246 involved_in positive regulation of RIG-I signaling pathway 1 ISS Homo_sapiens(9606) Process
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