Ensembl ID ENSG00000108771 Gene ID 79132 Accession 29517
Gene Symbol DHX58 Alias LGP2;RLR-3;D11LGP2;D11lgp2e Full Name DExH-box helicase 58
Position 17 : 42101404 - 42112714 Length 11311 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary Enables double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Involved in negative regulation of defense response and negative regulation of type I interferon production. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000108771 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000108771 DHX58 0.65 1.39e-15 BRCA
ENSG00000108771 DHX58 0.87 2.51e-16 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000108771 DHX58 cancer 20930504
ENSG00000108771 DHX58 cancer 22427729
ENSG00000108771 DHX58 HNSCC 23484008
ENSG00000108771 DHX58 cancer 24029594
ENSG00000108771 DHX58 breast cancer 24336087
ENSG00000108771 DHX58 tumor 24434553
ENSG00000108771 DHX58 tumor 25205107
ENSG00000108771 DHX58 cancer 25950488
ENSG00000108771 DHX58 cancer 25997992
ENSG00000108771 DHX58 tumors 26432403
ENSG00000108771 DHX58 breast cancer 26921029
ENSG00000108771 DHX58 tumor 27034163
ENSG00000108771 DHX58 Cancer 28216575
ENSG00000108771 DHX58 cancer 28548063
ENSG00000108771 DHX58 cancer 28917654
ENSG00000108771 DHX58 cancer 29032202
ENSG00000108771 DHX58 non-small cell lung cancer 29541243
ENSG00000108771 DHX58 tumor 29686682
ENSG00000108771 DHX58 cancer 29989043
ENSG00000108771 DHX58 colorectal cancer 30004146
ENSG00000108771 DHX58 cancer 30179292
ENSG00000108771 DHX58 Tumour 30194441
ENSG00000108771 DHX58 cancer 30320341
ENSG00000108771 DHX58 cancer 30976817
ENSG00000108771 DHX58 cancer 31155231
ENSG00000108771 DHX58 tumor 31467924
ENSG00000108771 DHX58 cancer 31951181
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000108771 DHX58 MESO 0.00014 low
ENSG00000108771 DHX58 UVM 0.0033 high
ENSG00000108771 DHX58 UCEC 0.032 low
ENSG00000108771 DHX58 ACC 0.042 low
ENSG00000108771 DHX58 LUSC 0.019 high
ENSG00000108771 DHX58 HNSC 0.045 low
ENSG00000108771 DHX58 THYM 0.00047 high
ENSG00000108771 DHX58 BRCA 0.00056 low
ENSG00000108771 DHX58 COAD 0.0012 high
ENSG00000108771 DHX58 UCS 0.013 low
ENSG00000108771 DHX58 ESCA 0.0033 low
ENSG00000108771 DHX58 DLBC 0.027 high
ENSG00000108771 DHX58 TGCT 0.0012 low
ENSG00000108771 DHX58 BLCA 0.003 low
ENSG00000108771 DHX58 LAML 0.00092 high
ENSG00000108771 DHX58 GBM 0.026 high
ENSG00000108771 DHX58 SKCM 5e-04 low
ENSG00000108771 DHX58 CESC 0.0024 low
ENSG00000108771 DHX58 LIHC 0.0018 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000108771 DHX58 ACC Del 2.507733 0.164803 0.583322 0.288889
ENSG00000108771 DHX58 PCPG Del 4.244199 0.120963 0.656331 0.209877
ENSG00000108771 DHX58 BRCA Del 5.836161 0.096837 0.427044 0.332407
ENSG00000108771 DHX58 STAD Amp 1.389389 0.152930 0.449237 0.226757
ENSG00000108771 DHX58 PRAD Del 1.288530 0.079878 0.425766 0.121951
ENSG00000108771 DHX58 UCEC Del 3.233262 0.074721 0.571922 0.202226