RBP Type
Non-canonical_RBPs
Diseases
Flaviviruses SARS-COV-2
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000108518 Gene ID
5216 Accession
8881
Symbol
PFN1
Alias
ALS18
Full Name
profilin 1
Status
Confidence
Length
3410 bases
Strand
Minus strand
Position
17 : 4945652 - 4949061
RNA binding domain
N.A.
Summary
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
PFN1-201
ENST00000225655
807
140aa
ENSP00000225655
PFN1-203
ENST00000574872
1173
104aa
ENSP00000465019
PFN1-202
ENST00000572383
539
165aa
ENSP00000460363
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108518 homo_sapiens ENSP00000351379 60.5839 43.7956 homo_sapiens ENSP00000225655 59.2857 42.8571 ENSG00000108518 homo_sapiens ENSP00000239940 73.5714 59.2857 homo_sapiens ENSP00000225655 73.5714 59.2857
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000108518 homo_sapiens ENSP00000225655 86.4286 85 nomascus_leucogenys ENSNLEP00000046571 94.5312 92.9688 ENSG00000108518 homo_sapiens ENSP00000225655 75.7143 75.7143 nomascus_leucogenys ENSNLEP00000040694 57.2973 57.2973 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 pan_paniscus ENSPPAP00000036892 52.1212 52.1212 ENSG00000108518 homo_sapiens ENSP00000225655 100 100 pongo_abelii ENSPPYP00000008839 63.9269 63.9269 ENSG00000108518 homo_sapiens ENSP00000225655 100 100 pan_troglodytes ENSPTRP00000014707 100 100 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 gorilla_gorilla ENSGGOP00000051542 52.1212 52.1212 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 95 ornithorhynchus_anatinus ENSOANP00000036941 97.8571 95 ENSG00000108518 homo_sapiens ENSP00000225655 96.4286 94.2857 dasypus_novemcinctus ENSDNOP00000032585 82.3171 80.4878 ENSG00000108518 homo_sapiens ENSP00000225655 76.4286 67.1429 dasypus_novemcinctus ENSDNOP00000028504 81.0606 71.2121 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 91.4286 erinaceus_europaeus ENSEEUP00000001720 95.7143 91.4286 ENSG00000108518 homo_sapiens ENSP00000225655 97.1429 94.2857 echinops_telfairi ENSETEP00000004456 97.1429 94.2857 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 cercocebus_atys ENSCATP00000009140 51.497 51.497 ENSG00000108518 homo_sapiens ENSP00000225655 100 100 macaca_fascicularis ENSMFAP00000028342 100 100 ENSG00000108518 homo_sapiens ENSP00000225655 100 100 macaca_mulatta ENSMMUP00000076194 100 100 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 60.7143 macaca_nemestrina ENSMNEP00000043029 50.8982 50.8982 ENSG00000108518 homo_sapiens ENSP00000225655 75.7143 75.7143 papio_anubis ENSPANP00000041810 56.6845 56.6845 ENSG00000108518 homo_sapiens ENSP00000225655 70 69.2857 mandrillus_leucophaeus ENSMLEP00000036177 94.2308 93.2692 ENSG00000108518 homo_sapiens ENSP00000225655 86.4286 80.7143 tursiops_truncatus ENSTTRP00000014544 86.4286 80.7143 ENSG00000108518 homo_sapiens ENSP00000225655 83.5714 78.5714 tursiops_truncatus ENSTTRP00000001219 95.9016 90.1639 ENSG00000108518 homo_sapiens ENSP00000225655 42.1429 40.7143 vulpes_vulpes ENSVVUP00000037918 81.9444 79.1667 ENSG00000108518 homo_sapiens ENSP00000225655 78.5714 69.2857 vulpes_vulpes ENSVVUP00000038518 28.6458 25.2604 ENSG00000108518 homo_sapiens ENSP00000225655 54.2857 45 vulpes_vulpes ENSVVUP00000024677 68.4685 56.7568 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 mus_spretus MGP_SPRETEiJ_P0029276 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 90.7143 87.8571 equus_asinus ENSEASP00005046455 60.1896 58.2938 ENSG00000108518 homo_sapiens ENSP00000225655 72.1429 66.4286 equus_asinus ENSEASP00005017444 76.5152 70.4545 ENSG00000108518 homo_sapiens ENSP00000225655 66.4286 62.1429 equus_asinus ENSEASP00005042985 85.3211 79.8165 ENSG00000108518 homo_sapiens ENSP00000225655 94.2857 90.7143 capra_hircus ENSCHIP00000010248 94.964 91.3669 ENSG00000108518 homo_sapiens ENSP00000225655 96.4286 92.1429 capra_hircus ENSCHIP00000003969 96.4286 92.1429 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 capra_hircus ENSCHIP00000031743 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 95 92.1429 loxodonta_africana ENSLAFP00000016537 95 92.1429 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 panthera_leo ENSPLOP00000021575 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 ailuropoda_melanoleuca ENSAMEP00000029200 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 56.4286 49.2857 ailuropoda_melanoleuca ENSAMEP00000033490 71.8182 62.7273 ENSG00000108518 homo_sapiens ENSP00000225655 53.5714 47.8571 ailuropoda_melanoleuca ENSAMEP00000021289 56.391 50.3759 ENSG00000108518 homo_sapiens ENSP00000225655 82.8571 78.5714 bos_indicus_hybrid ENSBIXP00005008365 84.6715 80.292 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 bos_indicus_hybrid ENSBIXP00005044827 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 70 67.1429 oryctolagus_cuniculus ENSOCUP00000000960 94.2308 90.3846 ENSG00000108518 homo_sapiens ENSP00000225655 72.1429 66.4286 equus_caballus ENSECAP00000041482 76.5152 70.4545 ENSG00000108518 homo_sapiens ENSP00000225655 95 92.1429 equus_caballus ENSECAP00000036024 71.123 68.984 ENSG00000108518 homo_sapiens ENSP00000225655 90.7143 87.8571 equus_caballus ENSECAP00000018633 60.7655 58.8517 ENSG00000108518 homo_sapiens ENSP00000225655 55.7143 45 canis_lupus_familiaris ENSCAFP00845027426 70.2703 56.7568 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 canis_lupus_familiaris ENSCAFP00845004958 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 52.8571 41.4286 canis_lupus_familiaris ENSCAFP00845021841 74 58 ENSG00000108518 homo_sapiens ENSP00000225655 69.2857 65.7143 panthera_pardus ENSPPRP00000012075 93.2692 88.4615 ENSG00000108518 homo_sapiens ENSP00000225655 40 35 panthera_pardus ENSPPRP00000023121 83.5821 73.1343 ENSG00000108518 homo_sapiens ENSP00000225655 63.5714 61.4286 marmota_marmota_marmota ENSMMMP00000020466 97.8022 94.5055 ENSG00000108518 homo_sapiens ENSP00000225655 88.5714 84.2857 balaenoptera_musculus ENSBMSP00010025085 88.5714 84.2857 ENSG00000108518 homo_sapiens ENSP00000225655 49.2857 45 balaenoptera_musculus ENSBMSP00010024368 86.25 78.75 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 87.8571 balaenoptera_musculus ENSBMSP00010026688 95.7143 87.8571 ENSG00000108518 homo_sapiens ENSP00000225655 97.1429 93.5714 cavia_porcellus ENSCPOP00000029499 97.1429 93.5714 ENSG00000108518 homo_sapiens ENSP00000225655 49.2857 42.8571 felis_catus ENSFCAP00000030761 92 80 ENSG00000108518 homo_sapiens ENSP00000225655 39.2857 35 felis_catus ENSFCAP00000021344 85.9375 76.5625 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 felis_catus ENSFCAP00000010380 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 47.1429 39.2857 felis_catus ENSFCAP00000048298 64.0777 53.3981 ENSG00000108518 homo_sapiens ENSP00000225655 72.1429 62.8571 ursus_americanus ENSUAMP00000030878 68.7075 59.8639 ENSG00000108518 homo_sapiens ENSP00000225655 82.1429 75 ursus_americanus ENSUAMP00000003481 70.1219 64.0244 ENSG00000108518 homo_sapiens ENSP00000225655 41.4286 35 ursus_americanus ENSUAMP00000024618 86.5672 73.1343 ENSG00000108518 homo_sapiens ENSP00000225655 56.4286 49.2857 ursus_americanus ENSUAMP00000031931 79.798 69.697 ENSG00000108518 homo_sapiens ENSP00000225655 96.4286 90 monodelphis_domestica ENSMODP00000006533 96.4286 90 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 bison_bison_bison ENSBBBP00000005220 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 90 monodon_monoceros ENSMMNP00015028863 45.7338 43.0034 ENSG00000108518 homo_sapiens ENSP00000225655 37.8571 34.2857 monodon_monoceros ENSMMNP00015000457 80.303 72.7273 ENSG00000108518 homo_sapiens ENSP00000225655 73.5714 67.1429 sus_scrofa ENSSSCP00000048979 79.845 72.8682 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 sus_scrofa ENSSSCP00000018967 61.8834 60.0897 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 95.7143 microcebus_murinus ENSMICP00000034794 97.8571 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 79.2857 74.2857 octodon_degus ENSODEP00000018387 90.9836 85.2459 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 95 octodon_degus ENSODEP00000023402 97.8571 95 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 jaculus_jaculus ENSJJAP00000016079 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 ovis_aries_rambouillet ENSOARP00020032786 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 82.1429 75 ovis_aries_rambouillet ENSOARP00020022285 56.3725 51.4706 ENSG00000108518 homo_sapiens ENSP00000225655 69.2857 65.7143 ursus_maritimus ENSUMAP00000018962 93.2692 88.4615 ENSG00000108518 homo_sapiens ENSP00000225655 56.4286 49.2857 ursus_maritimus ENSUMAP00000029601 79.798 69.697 ENSG00000108518 homo_sapiens ENSP00000225655 41.4286 35 ursus_maritimus ENSUMAP00000029257 86.5672 73.1343 ENSG00000108518 homo_sapiens ENSP00000225655 70.7143 62.1429 ursus_maritimus ENSUMAP00000009822 42.6724 37.5 ENSG00000108518 homo_sapiens ENSP00000225655 60 57.1429 ochotona_princeps ENSOPRP00000010204 93.3333 88.8889 ENSG00000108518 homo_sapiens ENSP00000225655 63.5714 61.4286 ochotona_princeps ENSOPRP00000011646 92.7083 89.5833 ENSG00000108518 homo_sapiens ENSP00000225655 87.8571 81.4286 delphinapterus_leucas ENSDLEP00000016839 87.8571 81.4286 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 90 delphinapterus_leucas ENSDLEP00000027904 95.7143 90 ENSG00000108518 homo_sapiens ENSP00000225655 50 47.8571 delphinapterus_leucas ENSDLEP00000002408 87.5 83.75 ENSG00000108518 homo_sapiens ENSP00000225655 50 45 physeter_catodon ENSPCTP00005029363 76.087 68.4783 ENSG00000108518 homo_sapiens ENSP00000225655 95 90.7143 physeter_catodon ENSPCTP00005020435 95 90.7143 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 mus_caroli MGP_CAROLIEiJ_P0027895 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 mus_musculus ENSMUSP00000018437 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 95.7143 dipodomys_ordii ENSDORP00000022082 97.8571 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 aotus_nancymaae ENSANAP00000000313 53.75 53.75 ENSG00000108518 homo_sapiens ENSP00000225655 100 99.2857 saimiri_boliviensis_boliviensis ENSSBOP00000022238 100 99.2857 ENSG00000108518 homo_sapiens ENSP00000225655 63.5714 60.7143 saimiri_boliviensis_boliviensis ENSSBOP00000029838 88.1188 84.1584 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 57.8571 vicugna_pacos ENSVPAP00000004945 95.5556 90 ENSG00000108518 homo_sapiens ENSP00000225655 100 100 chlorocebus_sabaeus ENSCSAP00000009111 100 100 ENSG00000108518 homo_sapiens ENSP00000225655 67.1429 65 tupaia_belangeri ENSTBEP00000009000 97.9167 94.7917 ENSG00000108518 homo_sapiens ENSP00000225655 97.1429 94.2857 mesocricetus_auratus ENSMAUP00000013197 97.1429 94.2857 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 91.4286 mesocricetus_auratus ENSMAUP00000005330 95.7143 91.4286 ENSG00000108518 homo_sapiens ENSP00000225655 95.7143 90 phocoena_sinus ENSPSNP00000027006 45.5782 42.8571 ENSG00000108518 homo_sapiens ENSP00000225655 50 46.4286 phocoena_sinus ENSPSNP00000027580 87.5 81.25 ENSG00000108518 homo_sapiens ENSP00000225655 51.4286 46.4286 camelus_dromedarius ENSCDRP00005030375 76.5957 69.1489 ENSG00000108518 homo_sapiens ENSP00000225655 70 60 camelus_dromedarius ENSCDRP00005009491 57.9882 49.7041 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 camelus_dromedarius ENSCDRP00005021258 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 89.2857 82.8571 camelus_dromedarius ENSCDRP00005013971 83.8926 77.8523 ENSG00000108518 homo_sapiens ENSP00000225655 89.2857 84.2857 carlito_syrichta ENSTSYP00000016065 89.2857 84.2857 ENSG00000108518 homo_sapiens ENSP00000225655 70 65.7143 panthera_tigris_altaica ENSPTIP00000017432 94.2308 88.4615 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 rattus_norvegicus ENSRNOP00000093393 66.0287 64.1148 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 96.4286 prolemur_simus ENSPSMP00000027933 98.5714 96.4286 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 microtus_ochrogaster ENSMOCP00000002018 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 72.1429 67.8571 microtus_ochrogaster ENSMOCP00000009537 85.5932 80.5085 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 microtus_ochrogaster ENSMOCP00000003215 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 75 72.8571 microtus_ochrogaster ENSMOCP00000019612 98.1308 95.3271 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 56.4286 peromyscus_maniculatus_bairdii ENSPEMP00000003050 93.4066 86.8132 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 peromyscus_maniculatus_bairdii ENSPEMP00000030209 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 68.5714 64.2857 bos_mutus ENSBMUP00000007106 89.7196 84.1122 ENSG00000108518 homo_sapiens ENSP00000225655 72.8571 67.8571 bos_mutus ENSBMUP00000007017 74.4526 69.3431 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 mus_spicilegus ENSMSIP00000029639 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 64.2857 57.8571 cricetulus_griseus_chok1gshd ENSCGRP00001006313 86.5385 77.8846 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 cricetulus_griseus_chok1gshd ENSCGRP00001011526 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 pteropus_vampyrus ENSPVAP00000003576 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 91.4286 80.7143 myotis_lucifugus ENSMLUP00000012775 90.1408 79.5775 ENSG00000108518 homo_sapiens ENSP00000225655 59.2857 45.7143 myotis_lucifugus ENSMLUP00000022591 66.9355 51.6129 ENSG00000108518 homo_sapiens ENSP00000225655 96.4286 91.4286 vombatus_ursinus ENSVURP00010001904 96.4286 91.4286 ENSG00000108518 homo_sapiens ENSP00000225655 95 90 rhinolophus_ferrumequinum ENSRFEP00010024443 94.3262 89.3617 ENSG00000108518 homo_sapiens ENSP00000225655 47.8571 40.7143 neovison_vison ENSNVIP00000026734 69.0722 58.7629 ENSG00000108518 homo_sapiens ENSP00000225655 73.5714 70 neovison_vison ENSNVIP00000004808 95.3704 90.7407 ENSG00000108518 homo_sapiens ENSP00000225655 69.2857 65.7143 neovison_vison ENSNVIP00000025135 93.2692 88.4615 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 bos_taurus ENSBTAP00000006465 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 93.5714 bos_taurus ENSBTAP00000050051 97.8571 93.5714 ENSG00000108518 homo_sapiens ENSP00000225655 92.8571 86.4286 heterocephalus_glaber_female ENSHGLP00000048035 43.6242 40.604 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 rhinopithecus_bieti ENSRBIP00000020122 51.497 51.497 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 98.5714 rhinopithecus_bieti ENSRBIP00000002165 98.5714 98.5714 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 canis_lupus_dingo ENSCAFP00020013924 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 55.7143 45 canis_lupus_dingo ENSCAFP00020007952 70.2703 56.7568 ENSG00000108518 homo_sapiens ENSP00000225655 90.7143 89.2857 sciurus_vulgaris ENSSVLP00005015227 60.7655 59.8086 ENSG00000108518 homo_sapiens ENSP00000225655 96.4286 91.4286 phascolarctos_cinereus ENSPCIP00000025471 96.4286 91.4286 ENSG00000108518 homo_sapiens ENSP00000225655 95 92.1429 procavia_capensis ENSPCAP00000000262 97.0803 94.1606 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 nannospalax_galili ENSNGAP00000017970 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 87.1429 82.1429 nannospalax_galili ENSNGAP00000015611 94.5736 89.1473 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 bos_grunniens ENSBGRP00000041866 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 chinchilla_lanigera ENSCLAP00000014970 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 80 75 cervus_hanglu_yarkandensis ENSCHYP00000003154 82.963 77.7778 ENSG00000108518 homo_sapiens ENSP00000225655 82.8571 77.8571 cervus_hanglu_yarkandensis ENSCHYP00000022482 95.8678 90.0826 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 cervus_hanglu_yarkandensis ENSCHYP00000021162 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95.7143 catagonus_wagneri ENSCWAP00000001728 98.5714 95.7143 ENSG00000108518 homo_sapiens ENSP00000225655 55.7143 50 catagonus_wagneri ENSCWAP00000009771 73.5849 66.0377 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 96.4286 ictidomys_tridecemlineatus ENSSTOP00000020460 98.5714 96.4286 ENSG00000108518 homo_sapiens ENSP00000225655 74.2857 62.8571 otolemur_garnettii ENSOGAP00000020142 76.4706 64.7059 ENSG00000108518 homo_sapiens ENSP00000225655 67.8571 65 cebus_imitator ENSCCAP00000000906 92.233 88.3495 ENSG00000108518 homo_sapiens ENSP00000225655 100 99.2857 cebus_imitator ENSCCAP00000028195 100 99.2857 ENSG00000108518 homo_sapiens ENSP00000225655 97.1429 95 urocitellus_parryii ENSUPAP00010007551 69.3878 67.8571 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 moschus_moschiferus ENSMMSP00000008936 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 61.4286 rhinopithecus_roxellana ENSRROP00000015211 51.497 51.497 ENSG00000108518 homo_sapiens ENSP00000225655 98.5714 95 mus_pahari MGP_PahariEiJ_P0034643 98.5714 95 ENSG00000108518 homo_sapiens ENSP00000225655 97.8571 96.4286 propithecus_coquereli ENSPCOP00000016281 51.8939 51.1364 ENSG00000108518 homo_sapiens ENSP00000225655 58.5714 42.8571 eptatretus_burgeri ENSEBUP00000002153 58.9928 43.1655 ENSG00000108518 homo_sapiens ENSP00000225655 66.4286 45 clupea_harengus ENSCHAP00000058859 65.9574 44.6809 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 35 danio_rerio ENSDARP00000109185 60.2837 34.7518 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 35.7143 carassius_auratus ENSCARP00000091326 60.9929 35.461 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 37.1429 carassius_auratus ENSCARP00000011836 60.2837 36.8794 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 35.7143 carassius_auratus ENSCARP00000072323 60.9929 35.461 ENSG00000108518 homo_sapiens ENSP00000225655 60 40 astyanax_mexicanus ENSAMXP00000053794 59.5745 39.7163 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 39.2857 ictalurus_punctatus ENSIPUP00000006389 60.2837 39.0071 ENSG00000108518 homo_sapiens ENSP00000225655 64.2857 42.1429 esox_lucius ENSELUP00000054125 62.9371 41.2587 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 37.8571 electrophorus_electricus ENSEEEP00000022367 57.4468 37.5887 ENSG00000108518 homo_sapiens ENSP00000225655 62.8571 39.2857 oncorhynchus_kisutch ENSOKIP00005088006 61.5385 38.4615 ENSG00000108518 homo_sapiens ENSP00000225655 63.5714 40 oncorhynchus_mykiss ENSOMYP00000126121 62.2378 39.1608 ENSG00000108518 homo_sapiens ENSP00000225655 63.5714 36.4286 salmo_salar ENSSSAP00000169707 62.2378 35.6643 ENSG00000108518 homo_sapiens ENSP00000225655 47.1429 24.2857 salmo_trutta ENSSTUP00000058731 64.7059 33.3333 ENSG00000108518 homo_sapiens ENSP00000225655 58.5714 41.4286 gadus_morhua ENSGMOP00000062948 54.6667 38.6667 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 38.5714 oreochromis_niloticus ENSONIP00000060254 57.0423 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 38.5714 haplochromis_burtoni ENSHBUP00000031568 57.0423 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 57.1429 38.5714 astatotilapia_calliptera ENSACLP00000008187 56.338 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 35.7143 lates_calcarifer ENSLCAP00010032454 57.0423 35.2113 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 35.7143 lates_calcarifer ENSLCAP00010046400 57.0423 35.2113 ENSG00000108518 homo_sapiens ENSP00000225655 66.4286 52.8571 xenopus_tropicalis ENSXETP00000108927 67.3913 53.6232 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 47.1429 chrysemys_picta_bellii ENSCPBP00000035589 84.1584 65.3465 ENSG00000108518 homo_sapiens ENSP00000225655 52.1429 46.4286 sphenodon_punctatus ENSSPUP00000007258 91.25 81.25 ENSG00000108518 homo_sapiens ENSP00000225655 65.7143 55 crocodylus_porosus ENSCPRP00005006944 77.3109 64.7059 ENSG00000108518 homo_sapiens ENSP00000225655 43.5714 37.1429 serinus_canaria ENSSCAP00000002835 52.5862 44.8276 ENSG00000108518 homo_sapiens ENSP00000225655 75.7143 66.4286 parus_major ENSPMJP00000007080 66.25 58.125 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 38.5714 neolamprologus_brichardi ENSNBRP00000030524 57.0423 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 72.8571 61.4286 naja_naja ENSNNAP00000014161 47.2222 39.8148 ENSG00000108518 homo_sapiens ENSP00000225655 61.4286 51.4286 naja_naja ENSNNAP00000011028 78.8991 66.055 ENSG00000108518 homo_sapiens ENSP00000225655 77.8571 68.5714 podarcis_muralis ENSPMRP00000028562 33.0303 29.0909 ENSG00000108518 homo_sapiens ENSP00000225655 82.8571 72.1429 taeniopygia_guttata ENSTGUP00000023125 82.8571 72.1429 ENSG00000108518 homo_sapiens ENSP00000225655 55 41.4286 erpetoichthys_calabaricus ENSECRP00000000099 58.7786 44.2748 ENSG00000108518 homo_sapiens ENSP00000225655 71.4286 51.4286 erpetoichthys_calabaricus ENSECRP00000010581 72.9927 52.5547 ENSG00000108518 homo_sapiens ENSP00000225655 70.7143 52.8571 erpetoichthys_calabaricus ENSECRP00000010568 71.223 53.2374 ENSG00000108518 homo_sapiens ENSP00000225655 55.7143 34.2857 kryptolebias_marmoratus ENSKMAP00000009853 54.9296 33.8028 ENSG00000108518 homo_sapiens ENSP00000225655 90 80.7143 salvator_merianae ENSSMRP00000001400 90 80.7143 ENSG00000108518 homo_sapiens ENSP00000225655 57.1429 36.4286 oryzias_javanicus ENSOJAP00000026797 55.1724 35.1724 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 39.2857 amphilophus_citrinellus ENSACIP00000004860 55.102 37.415 ENSG00000108518 homo_sapiens ENSP00000225655 86.4286 70 pelodiscus_sinensis ENSPSIP00000002056 86.4286 70 ENSG00000108518 homo_sapiens ENSP00000225655 49.2857 38.5714 chelonoidis_abingdonii ENSCABP00000010534 80.2326 62.7907 ENSG00000108518 homo_sapiens ENSP00000225655 57.1429 37.1429 cynoglossus_semilaevis ENSCSEP00000009197 58.3942 37.9562 ENSG00000108518 homo_sapiens ENSP00000225655 55 35.7143 poecilia_formosa ENSPFOP00000028112 53.8462 34.965 ENSG00000108518 homo_sapiens ENSP00000225655 65 46.4286 myripristis_murdjan ENSMMDP00005041127 65.4676 46.7626 ENSG00000108518 homo_sapiens ENSP00000225655 60 46.4286 terrapene_carolina_triunguis ENSTMTP00000004545 83.1683 64.3564 ENSG00000108518 homo_sapiens ENSP00000225655 57.8571 38.5714 pundamilia_nyererei ENSPNYP00000014099 57.0423 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 56.4286 34.2857 mastacembelus_armatus ENSMAMP00000043937 56.4286 34.2857 ENSG00000108518 homo_sapiens ENSP00000225655 85.7143 74.2857 aquila_chrysaetos_chrysaetos ENSACCP00020020144 85.7143 74.2857 ENSG00000108518 homo_sapiens ENSP00000225655 57.1429 37.8571 cyprinodon_variegatus ENSCVAP00000028314 55.5556 36.8056 ENSG00000108518 homo_sapiens ENSP00000225655 62.8571 42.1429 denticeps_clupeoides ENSDCDP00000037092 40.1826 26.9406 ENSG00000108518 homo_sapiens ENSP00000225655 55.7143 50.7143 ficedula_albicollis ENSFALP00000032110 61.9048 56.3492 ENSG00000108518 homo_sapiens ENSP00000225655 60 34.2857 cyprinus_carpio_carpio ENSCCRP00000152304 59.5745 34.0426 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 34.2857 cyprinus_carpio_carpio ENSCCRP00000029162 60.2837 34.0426 ENSG00000108518 homo_sapiens ENSP00000225655 55 35.7143 poecilia_latipinna ENSPLAP00000020966 53.8462 34.965 ENSG00000108518 homo_sapiens ENSP00000225655 60.7143 34.2857 sinocyclocheilus_grahami ENSSGRP00000006221 60.2837 34.0426 ENSG00000108518 homo_sapiens ENSP00000225655 60 33.5714 sinocyclocheilus_grahami ENSSGRP00000048773 59.5745 33.3333 ENSG00000108518 homo_sapiens ENSP00000225655 57.1429 38.5714 maylandia_zebra ENSMZEP00005028228 56.338 38.0282 ENSG00000108518 homo_sapiens ENSP00000225655 62.1429 47.8571 paramormyrops_kingsleyae ENSPKIP00000021256 61.7021 47.5177 ENSG00000108518 homo_sapiens ENSP00000225655 55 40 paramormyrops_kingsleyae ENSPKIP00000005438 47.2393 34.3558 ENSG00000108518 homo_sapiens ENSP00000225655 64.2857 47.1429 scleropages_formosus ENSSFOP00015035066 63.8298 46.8085 ENSG00000108518 homo_sapiens ENSP00000225655 65.7143 52.1429 leptobrachium_leishanense ENSLLEP00000049077 66.6667 52.8986 ENSG00000108518 homo_sapiens ENSP00000225655 56.4286 32.8571 oryzias_melastigma ENSOMEP00000006105 55.6338 32.3944
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000774 enables adenyl-nucleotide exchange factor activity 1 IDA Homo_sapiens(9606) Function GO:0001784 enables phosphotyrosine residue binding 1 IPI Homo_sapiens(9606) Function GO:0001843 involved_in neural tube closure 1 IEA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003779 enables actin binding 2 IBA,IPI Homo_sapiens(9606) Function GO:0003785 enables actin monomer binding 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005546 enables phosphatidylinositol-4,5-bisphosphate binding 1 IDA Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005737 is_active_in cytoplasm 2 IBA,IDA Homo_sapiens(9606) Component GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0005856 located_in cytoskeleton 1 IEA Homo_sapiens(9606) Component GO:0005925 located_in focal adhesion 1 HDA Homo_sapiens(9606) Component GO:0005938 located_in cell cortex 1 IDA Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IEA Homo_sapiens(9606) Process GO:0010634 involved_in positive regulation of epithelial cell migration 1 IMP Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0030036 involved_in actin cytoskeleton organization 1 IEA Homo_sapiens(9606) Process GO:0030833 involved_in regulation of actin filament polymerization 1 IBA Homo_sapiens(9606) Process GO:0030837 involved_in negative regulation of actin filament polymerization 1 IDA Homo_sapiens(9606) Process GO:0030838 involved_in positive regulation of actin filament polymerization 1 IGI Homo_sapiens(9606) Process GO:0031267 enables small GTPase binding 1 IEA Homo_sapiens(9606) Function GO:0032232 involved_in negative regulation of actin filament bundle assembly 1 IMP Homo_sapiens(9606) Process GO:0032233 involved_in positive regulation of actin filament bundle assembly 1 IBA Homo_sapiens(9606) Process GO:0032781 involved_in positive regulation of ATP-dependent activity 1 IDA Homo_sapiens(9606) Process GO:0045296 enables cadherin binding 1 HDA Homo_sapiens(9606) Function GO:0050804 involved_in modulation of chemical synaptic transmission 1 IEA Homo_sapiens(9606) Process GO:0050821 involved_in protein stabilization 1 IDA Homo_sapiens(9606) Process GO:0051497 involved_in negative regulation of stress fiber assembly 1 IMP Homo_sapiens(9606) Process GO:0060074 involved_in synapse maturation 1 IEA Homo_sapiens(9606) Process GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:0070064 enables proline-rich region binding 1 IPI Homo_sapiens(9606) Function GO:0072562 located_in blood microparticle 1 HDA Homo_sapiens(9606) Component GO:0098885 involved_in modification of postsynaptic actin cytoskeleton 1 IEA Homo_sapiens(9606) Process GO:0098978 located_in glutamatergic synapse 1 IEA Homo_sapiens(9606) Component GO:1900029 involved_in positive regulation of ruffle assembly 1 IMP Homo_sapiens(9606) Process
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