RBP Type
Non-canonical_RBPs
Diseases
CancerCHIKV SARS-COV-OC43 Flaviviruses HIV IAV RV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
DataSet_01_247
Ensembl ID ENSG00000107581 Gene ID
8661
Accession
3271
Symbol
EIF3A
Alias
EIF3;P167;p180;p185;TIF32;EIF3S10;eIF3-p170;eIF3-theta
Full Name
eukaryotic translation initiation factor 3 subunit A
Status
Confidence
Length
47154 bases
Strand
Minus strand
Position
10 : 119033670 - 119080823
RNA binding domain
N.A.
Summary
Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of cytoplasmic translation initiation complex; and viral translational termination-reinitiation. Located in cytosol; nucleolus; and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
31363116
Serum anti-EIF3A autoantibody as a potential diagnostic marker for hepatocellular carcinoma.
Chang-Kyu Heo
2019-07-30
Scientific reports
31088929
Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae .
E Danielle Anderson
2019-05-14
mBio
33799492
Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin Identification.
Diep-Khanh Vo
2021-03-14
Cancers
36091067
Structural and functional analysis of the small GTPase ARF1 reveals a pivotal role of its GTP-binding domain in controlling of the generation of viral inclusion bodies and replication of grass carp reovirus.
Jie Zhang
2022-01-01
Frontiers in immunology
35354796
TRIM46 activates AKT/HK2 signaling by modifying PHLPP2 ubiquitylation to promote glycolysis and chemoresistance of lung cancer cells.
Jicheng Tantai
2022-03-30
Cell death & disease
32451507
m6 A-binding YTHDF proteins promote stress granule formation.
Ye Fu
2020-09-01
Nature chemical biology
25227463
Virus-mediated compartmentalization of the host translational machinery.
A Emily Desmet
2014-09-16
mBio
Name
Transcript ID
bp
Protein
Translation ID
EIF3A-201
ENST00000369144
6659
1382aa
ENSP00000358140
EIF3A-202
ENST00000462527
1192
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
7901 Albuminuria 3.85433975361434E-17 17903292
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000107581
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000107581 homo_sapiens ENSP00000358140 92.4747 91.534 nomascus_leucogenys ENSNLEP00000020219 97.7064 96.7125 ENSG00000107581 homo_sapiens ENSP00000358140 94.1389 93.6324 pan_paniscus ENSPPAP00000010176 98.8602 98.3283 ENSG00000107581 homo_sapiens ENSP00000358140 99.7106 99.4935 pongo_abelii ENSPPYP00000003148 98.9943 98.7787 ENSG00000107581 homo_sapiens ENSP00000358140 89.6527 88.9291 pan_troglodytes ENSPTRP00000005269 95.6757 94.9035 ENSG00000107581 homo_sapiens ENSP00000358140 82.1273 81.4038 gorilla_gorilla ENSGGOP00000000035 96.5957 95.7447 ENSG00000107581 homo_sapiens ENSP00000358140 92.6917 88.5673 ornithorhynchus_anatinus ENSOANP00000011713 95.597 91.3433 ENSG00000107581 homo_sapiens ENSP00000358140 92.2576 88.6397 sarcophilus_harrisii ENSSHAP00000001510 93.2699 89.6123 ENSG00000107581 homo_sapiens ENSP00000358140 59.7685 57.0912 notamacropus_eugenii ENSMEUP00000010907 61.0044 58.2718 ENSG00000107581 homo_sapiens ENSP00000358140 94.356 92.2576 choloepus_hoffmanni ENSCHOP00000007272 96.3784 94.235 ENSG00000107581 homo_sapiens ENSP00000358140 93.6324 91.2446 dasypus_novemcinctus ENSDNOP00000005944 95.3574 92.9256 ENSG00000107581 homo_sapiens ENSP00000358140 77.7858 75.1085 erinaceus_europaeus ENSEEUP00000004548 83.6576 80.7782 ENSG00000107581 homo_sapiens ENSP00000358140 83.068 79.5224 echinops_telfairi ENSETEP00000004102 84.226 80.631 ENSG00000107581 homo_sapiens ENSP00000358140 98.2634 97.5398 callithrix_jacchus ENSCJAP00000036407 99.5601 98.827 ENSG00000107581 homo_sapiens ENSP00000358140 99.1317 98.6975 cercocebus_atys ENSCATP00000028678 99.8542 99.4169 ENSG00000107581 homo_sapiens ENSP00000358140 99.8553 99.3488 macaca_fascicularis ENSMFAP00000018269 99.1379 98.6351 ENSG00000107581 homo_sapiens ENSP00000358140 89.7974 89.1462 macaca_mulatta ENSMMUP00000011779 97.6397 96.9315 ENSG00000107581 homo_sapiens ENSP00000358140 96.3097 95.152 macaca_nemestrina ENSMNEP00000003953 98.0118 96.8336 ENSG00000107581 homo_sapiens ENSP00000358140 99.8553 99.3488 papio_anubis ENSPANP00000016491 99.1379 98.6351 ENSG00000107581 homo_sapiens ENSP00000358140 97.3951 96.2373 mandrillus_leucophaeus ENSMLEP00000016089 97.7487 96.5868 ENSG00000107581 homo_sapiens ENSP00000358140 94.4284 92.547 tursiops_truncatus ENSTTRP00000001581 96.9539 95.0223 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.6324 vulpes_vulpes ENSVVUP00000014786 97.7778 95.8519 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.1983 mus_spretus MGP_SPRETEiJ_P0051308 98.1399 95.8333 ENSG00000107581 homo_sapiens ENSP00000358140 92.2576 90.4486 equus_asinus ENSEASP00005051611 97.1799 95.2744 ENSG00000107581 homo_sapiens ENSP00000358140 95.8032 93.7048 capra_hircus ENSCHIP00000016335 96.7836 94.6637 ENSG00000107581 homo_sapiens ENSP00000358140 92.1852 89.2185 loxodonta_africana ENSLAFP00000010825 96.0784 92.9864 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.4153 panthera_leo ENSPLOP00000030159 98.2143 96.0565 ENSG00000107581 homo_sapiens ENSP00000358140 91.0275 89.1462 ailuropoda_melanoleuca ENSAMEP00000010495 93.6012 91.6667 ENSG00000107581 homo_sapiens ENSP00000358140 96.3097 94.2836 bos_indicus_hybrid ENSBIXP00005016139 97.4378 95.388 ENSG00000107581 homo_sapiens ENSP00000358140 96.165 93.7771 oryctolagus_cuniculus ENSOCUP00000004327 97.5771 95.1542 ENSG00000107581 homo_sapiens ENSP00000358140 95.7308 94.1389 equus_caballus ENSECAP00000089369 95.8001 94.2071 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.6324 canis_lupus_familiaris ENSCAFP00845022013 97.8487 95.9941 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.4153 panthera_pardus ENSPPRP00000016724 98.2143 96.0565 ENSG00000107581 homo_sapiens ENSP00000358140 93.5601 92.1129 marmota_marmota_marmota ENSMMMP00000000371 97.145 95.6424 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.9942 balaenoptera_musculus ENSBMSP00010018506 96.5593 95.0952 ENSG00000107581 homo_sapiens ENSP00000358140 95.152 93.1983 cavia_porcellus ENSCPOP00000023003 96.4784 94.4974 ENSG00000107581 homo_sapiens ENSP00000358140 95.2967 93.1983 felis_catus ENSFCAP00000009894 98.064 95.9047 ENSG00000107581 homo_sapiens ENSP00000358140 94.2113 92.2576 ursus_americanus ENSUAMP00000011719 96.9471 94.9367 ENSG00000107581 homo_sapiens ENSP00000358140 86.2518 83.1404 monodelphis_domestica ENSMODP00000058505 95.2838 91.8465 ENSG00000107581 homo_sapiens ENSP00000358140 95.369 93.343 bison_bison_bison ENSBBBP00000000977 96.2044 94.1606 ENSG00000107581 homo_sapiens ENSP00000358140 94.9349 93.1259 monodon_monoceros ENSMMNP00015027357 97.2572 95.404 ENSG00000107581 homo_sapiens ENSP00000358140 95.7308 93.7771 sus_scrofa ENSSSCP00000011378 96.1483 94.186 ENSG00000107581 homo_sapiens ENSP00000358140 95.0072 93.7048 microcebus_murinus ENSMICP00000006908 98.0583 96.714 ENSG00000107581 homo_sapiens ENSP00000358140 93.1259 90.6657 octodon_degus ENSODEP00000024292 97.9452 95.3577 ENSG00000107581 homo_sapiens ENSP00000358140 91.3169 89.0014 jaculus_jaculus ENSJJAP00000011818 96.9278 94.47 ENSG00000107581 homo_sapiens ENSP00000358140 96.0926 94.0666 ovis_aries_rambouillet ENSOARP00020017257 96.2319 94.2029 ENSG00000107581 homo_sapiens ENSP00000358140 89.5803 86.3965 ursus_maritimus ENSUMAP00000003862 92.0446 88.7732 ENSG00000107581 homo_sapiens ENSP00000358140 81.7656 78.6541 ochotona_princeps ENSOPRP00000004420 83.7037 80.5185 ENSG00000107581 homo_sapiens ENSP00000358140 94.9349 93.0535 delphinapterus_leucas ENSDLEP00000011990 97.2572 95.3299 ENSG00000107581 homo_sapiens ENSP00000358140 95.5861 94.0666 physeter_catodon ENSPCTP00005030732 97.2754 95.729 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.1259 mus_caroli MGP_CAROLIEiJ_P0049293 97.4151 95.0517 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.1259 mus_musculus ENSMUSP00000025955 98.1399 95.7589 ENSG00000107581 homo_sapiens ENSP00000358140 95.152 92.9088 dipodomys_ordii ENSDORP00000003258 98.281 95.9641 ENSG00000107581 homo_sapiens ENSP00000358140 93.0535 90.2316 mustela_putorius_furo ENSMPUP00000003062 95.4006 92.5074 ENSG00000107581 homo_sapiens ENSP00000358140 97.3951 96.8162 aotus_nancymaae ENSANAP00000008294 99.5562 98.9645 ENSG00000107581 homo_sapiens ENSP00000358140 94.1389 93.4877 saimiri_boliviensis_boliviensis ENSSBOP00000002376 98.486 97.8047 ENSG00000107581 homo_sapiens ENSP00000358140 92.547 90.8828 vicugna_pacos ENSVPAP00000011542 96.3102 94.5783 ENSG00000107581 homo_sapiens ENSP00000358140 83.9363 82.9233 chlorocebus_sabaeus ENSCSAP00000001103 94.6939 93.551 ENSG00000107581 homo_sapiens ENSP00000358140 77.1346 76.0492 tupaia_belangeri ENSTBEP00000008825 81.5608 80.4132 ENSG00000107581 homo_sapiens ENSP00000358140 80.9696 79.0159 mesocricetus_auratus ENSMAUP00000012307 96.5488 94.2192 ENSG00000107581 homo_sapiens ENSP00000358140 95.369 93.5601 phocoena_sinus ENSPSNP00000030271 97.7745 95.9199 ENSG00000107581 homo_sapiens ENSP00000358140 96.2373 94.6454 camelus_dromedarius ENSCDRP00005024166 98.3728 96.7456 ENSG00000107581 homo_sapiens ENSP00000358140 95.9479 94.7902 carlito_syrichta ENSTSYP00000028547 97.3568 96.1821 ENSG00000107581 homo_sapiens ENSP00000358140 94.2836 92.1852 panthera_tigris_altaica ENSPTIP00000013809 96.9494 94.7917 ENSG00000107581 homo_sapiens ENSP00000358140 95.369 93.1983 rattus_norvegicus ENSRNOP00000063484 97.3412 95.1256 ENSG00000107581 homo_sapiens ENSP00000358140 95.152 93.9219 prolemur_simus ENSPSMP00000016054 98.3545 97.083 ENSG00000107581 homo_sapiens ENSP00000358140 94.6454 92.9088 microtus_ochrogaster ENSMOCP00000003045 97.4665 95.6781 ENSG00000107581 homo_sapiens ENSP00000358140 81.8379 78.9436 sorex_araneus ENSSARP00000012511 87.7424 84.6393 ENSG00000107581 homo_sapiens ENSP00000358140 95.6585 93.7771 peromyscus_maniculatus_bairdii ENSPEMP00000000123 98.29 96.3569 ENSG00000107581 homo_sapiens ENSP00000358140 95.8755 93.8495 bos_mutus ENSBMUP00000008053 96.1538 94.1219 ENSG00000107581 homo_sapiens ENSP00000358140 95.4414 93.1983 mus_spicilegus ENSMSIP00000033750 98.1399 95.8333 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.6324 cricetulus_griseus_chok1gshd ENSCGRP00001003231 96.9875 95.0771 ENSG00000107581 homo_sapiens ENSP00000358140 94.2113 91.8958 pteropus_vampyrus ENSPVAP00000002970 95.2451 92.9042 ENSG00000107581 homo_sapiens ENSP00000358140 96.4544 94.0666 myotis_lucifugus ENSMLUP00000005278 96.315 93.9306 ENSG00000107581 homo_sapiens ENSP00000358140 92.2576 88.3502 vombatus_ursinus ENSVURP00010032712 94.5846 90.5786 ENSG00000107581 homo_sapiens ENSP00000358140 97.178 94.2836 rhinolophus_ferrumequinum ENSRFEP00010019606 94.7109 91.89 ENSG00000107581 homo_sapiens ENSP00000358140 91.6064 89.508 neovison_vison ENSNVIP00000006274 94.4776 92.3134 ENSG00000107581 homo_sapiens ENSP00000358140 96.2373 94.1389 bos_taurus ENSBTAP00000053182 96.657 94.5494 ENSG00000107581 homo_sapiens ENSP00000358140 94.7902 92.6194 heterocephalus_glaber_female ENSHGLP00000018529 98.1273 95.8801 ENSG00000107581 homo_sapiens ENSP00000358140 96.165 95.6585 rhinopithecus_bieti ENSRBIP00000039328 98.8104 98.29 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.7048 canis_lupus_dingo ENSCAFP00020017274 97.7778 95.9259 ENSG00000107581 homo_sapiens ENSP00000358140 96.3821 94.8625 sciurus_vulgaris ENSSVLP00005003821 98.2301 96.6814 ENSG00000107581 homo_sapiens ENSP00000358140 89.4356 84.9493 phascolarctos_cinereus ENSPCIP00000038639 89.7603 85.2578 ENSG00000107581 homo_sapiens ENSP00000358140 91.6064 87.6266 procavia_capensis ENSPCAP00000006572 94.9737 90.8477 ENSG00000107581 homo_sapiens ENSP00000358140 91.8234 89.725 nannospalax_galili ENSNGAP00000019891 94 91.8519 ENSG00000107581 homo_sapiens ENSP00000358140 96.165 94.1389 bos_grunniens ENSBGRP00000031730 96.5843 94.5494 ENSG00000107581 homo_sapiens ENSP00000358140 93.4877 91.6064 chinchilla_lanigera ENSCLAP00000011949 96.8516 94.9025 ENSG00000107581 homo_sapiens ENSP00000358140 92.8365 90.1592 cervus_hanglu_yarkandensis ENSCHYP00000010892 90.9284 88.3062 ENSG00000107581 homo_sapiens ENSP00000358140 91.6064 89.5803 catagonus_wagneri ENSCWAP00000024540 96.4939 94.3598 ENSG00000107581 homo_sapiens ENSP00000358140 87.1201 85.3111 ictidomys_tridecemlineatus ENSSTOP00000002247 96.0128 94.0191 ENSG00000107581 homo_sapiens ENSP00000358140 95.5861 93.9942 otolemur_garnettii ENSOGAP00000004087 95.7941 94.1987 ENSG00000107581 homo_sapiens ENSP00000358140 92.9088 91.6064 cebus_imitator ENSCCAP00000027854 96.3964 95.045 ENSG00000107581 homo_sapiens ENSP00000358140 95.9479 94.6454 urocitellus_parryii ENSUPAP00010008501 96.859 95.5442 ENSG00000107581 homo_sapiens ENSP00000358140 95.5137 93.4153 moschus_moschiferus ENSMMSP00000023553 98.2143 96.0565 ENSG00000107581 homo_sapiens ENSP00000358140 99.1317 98.6252 rhinopithecus_roxellana ENSRROP00000044861 99.564 99.0552 ENSG00000107581 homo_sapiens ENSP00000358140 95.369 93.4153 mus_pahari MGP_PahariEiJ_P0022254 97.4132 95.4176 ENSG00000107581 homo_sapiens ENSP00000358140 94.0666 92.6917 propithecus_coquereli ENSPCOP00000027713 98.5595 97.119 ENSG00000107581 homo_sapiens ENSP00000358140 45.4414 29.9566 caenorhabditis_elegans C27D11.1.1 58.3643 38.4758 ENSG00000107581 homo_sapiens ENSP00000358140 53.7627 38.4949 drosophila_melanogaster FBpp0312226 65.1754 46.6667 ENSG00000107581 homo_sapiens ENSP00000358140 54.3415 40.0868 ciona_intestinalis ENSCINP00000009993 71.4558 52.7117 ENSG00000107581 homo_sapiens ENSP00000358140 74.8191 64.7612 petromyzon_marinus ENSPMAP00000006265 75.1453 65.0436 ENSG00000107581 homo_sapiens ENSP00000358140 75.1085 64.11 eptatretus_burgeri ENSEBUP00000000432 69.6644 59.4631 ENSG00000107581 homo_sapiens ENSP00000358140 73.9508 65.5572 callorhinchus_milii ENSCMIP00000045264 87.6501 77.7015 ENSG00000107581 homo_sapiens ENSP00000358140 77.7135 70.4776 latimeria_chalumnae ENSLACP00000016956 81.4253 73.8438 ENSG00000107581 homo_sapiens ENSP00000358140 80.1013 72.2865 lepisosteus_oculatus ENSLOCP00000011886 87.5791 79.0348 ENSG00000107581 homo_sapiens ENSP00000358140 74.8915 66.8596 clupea_harengus ENSCHAP00000038186 80.0464 71.4617 ENSG00000107581 homo_sapiens ENSP00000358140 79.8119 72.2142 danio_rerio ENSDARP00000102398 87.056 78.7687 ENSG00000107581 homo_sapiens ENSP00000358140 78.8712 72.1418 carassius_auratus ENSCARP00000054172 86.8526 79.4422 ENSG00000107581 homo_sapiens ENSP00000358140 76.5557 69.6816 carassius_auratus ENSCARP00000047923 79.5489 72.406 ENSG00000107581 homo_sapiens ENSP00000358140 43.6324 41.6787 carassius_auratus ENSCARP00000134312 94.2188 90 ENSG00000107581 homo_sapiens ENSP00000358140 79.7395 72.576 astyanax_mexicanus ENSAMXP00000005419 85.4264 77.7519 ENSG00000107581 homo_sapiens ENSP00000358140 80.0289 72.2142 ictalurus_punctatus ENSIPUP00000029849 86.0031 77.605 ENSG00000107581 homo_sapiens ENSP00000358140 75.5427 67.6556 esox_lucius ENSELUP00000070454 79.6947 71.374 ENSG00000107581 homo_sapiens ENSP00000358140 76.5557 69.3198 electrophorus_electricus ENSEEEP00000044608 88.4615 80.1003 ENSG00000107581 homo_sapiens ENSP00000358140 75.9045 68.8857 oncorhynchus_kisutch ENSOKIP00005038504 83.0562 75.3761 ENSG00000107581 homo_sapiens ENSP00000358140 75.4703 68.2344 oncorhynchus_kisutch ENSOKIP00005012228 82.7121 74.7819 ENSG00000107581 homo_sapiens ENSP00000358140 75.8321 68.741 oncorhynchus_mykiss ENSOMYP00000098515 82.9114 75.1582 ENSG00000107581 homo_sapiens ENSP00000358140 74.4573 67.3661 oncorhynchus_mykiss ENSOMYP00000067018 80.8962 73.1918 ENSG00000107581 homo_sapiens ENSP00000358140 75.9768 68.6686 salmo_salar ENSSSAP00000016499 83.7989 75.7382 ENSG00000107581 homo_sapiens ENSP00000358140 75.1809 68.0897 salmo_salar ENSSSAP00000053366 82.3949 74.6233 ENSG00000107581 homo_sapiens ENSP00000358140 75.2533 68.0174 salmo_trutta ENSSTUP00000028996 82.4742 74.544 ENSG00000107581 homo_sapiens ENSP00000358140 76.0492 68.741 salmo_trutta ENSSTUP00000015523 83.4127 75.3968 ENSG00000107581 homo_sapiens ENSP00000358140 70.1158 63.097 gadus_morhua ENSGMOP00000040439 79.8188 71.8287 ENSG00000107581 homo_sapiens ENSP00000358140 78.8712 71.0564 fundulus_heteroclitus ENSFHEP00000016750 86.03 77.5059 ENSG00000107581 homo_sapiens ENSP00000358140 78.0029 70.767 poecilia_reticulata ENSPREP00000002862 85.6916 77.7424 ENSG00000107581 homo_sapiens ENSP00000358140 78.0029 71.1288 xiphophorus_maculatus ENSXMAP00000007984 86.1022 78.5144 ENSG00000107581 homo_sapiens ENSP00000358140 79.3777 71.4906 oryzias_latipes ENSORLP00000017833 87.0635 78.4127 ENSG00000107581 homo_sapiens ENSP00000358140 76.0492 67.7279 cyclopterus_lumpus ENSCLMP00005015373 81.6628 72.7273 ENSG00000107581 homo_sapiens ENSP00000358140 75.9045 68.5962 oreochromis_niloticus ENSONIP00000013005 85.0081 76.8233 ENSG00000107581 homo_sapiens ENSP00000358140 75.6874 68.5962 haplochromis_burtoni ENSHBUP00000028446 84.6278 76.699 ENSG00000107581 homo_sapiens ENSP00000358140 77.5687 70.1158 astatotilapia_calliptera ENSACLP00000028993 87.2964 78.9088 ENSG00000107581 homo_sapiens ENSP00000358140 77.4964 70.9117 sparus_aurata ENSSAUP00010052266 87.0024 79.6101 ENSG00000107581 homo_sapiens ENSP00000358140 77.7135 71.6353 lates_calcarifer ENSLCAP00010018384 86.3344 79.582 ENSG00000107581 homo_sapiens ENSP00000358140 81.6932 73.7337 xenopus_tropicalis ENSXETP00000022579 81.1646 73.2567 ENSG00000107581 homo_sapiens ENSP00000358140 86.3242 79.8842 chrysemys_picta_bellii ENSCPBP00000002664 89.5646 82.8829 ENSG00000107581 homo_sapiens ENSP00000358140 84.7323 78.5094 crocodylus_porosus ENSCPRP00005015103 88.8467 82.3217 ENSG00000107581 homo_sapiens ENSP00000358140 85.2388 78.8712 laticauda_laticaudata ENSLLTP00000014511 85.6727 79.2727 ENSG00000107581 homo_sapiens ENSP00000358140 87.9884 81.5485 notechis_scutatus ENSNSUP00000002471 85.3933 79.1433 ENSG00000107581 homo_sapiens ENSP00000358140 88.2055 81.8379 pseudonaja_textilis ENSPTXP00000016580 88.6545 82.2545 ENSG00000107581 homo_sapiens ENSP00000358140 76.7728 71.8524 anas_platyrhynchos_platyrhynchos ENSAPLP00000006298 88.861 83.1658 ENSG00000107581 homo_sapiens ENSP00000358140 87.3372 80.8972 gallus_gallus ENSGALP00010002903 86.5854 80.2009 ENSG00000107581 homo_sapiens ENSP00000358140 85.1664 78.7265 meleagris_gallopavo ENSMGAP00000011828 86.9919 80.4139 ENSG00000107581 homo_sapiens ENSP00000358140 86.5412 79.5948 serinus_canaria ENSSCAP00000019749 87.7476 80.7043 ENSG00000107581 homo_sapiens ENSP00000358140 87.7713 80.8249 parus_major ENSPMJP00000006662 87.0782 80.1866 ENSG00000107581 homo_sapiens ENSP00000358140 86.9754 79.8842 anolis_carolinensis ENSACAP00000021779 83.1834 76.4014 ENSG00000107581 homo_sapiens ENSP00000358140 77.7135 70.1881 neolamprologus_brichardi ENSNBRP00000022824 87.034 78.6062 ENSG00000107581 homo_sapiens ENSP00000358140 88.1331 81.9103 naja_naja ENSNNAP00000009060 87 80.8571 ENSG00000107581 homo_sapiens ENSP00000358140 87.699 81.259 podarcis_muralis ENSPMRP00000009891 85.6537 79.364 ENSG00000107581 homo_sapiens ENSP00000358140 82.7786 76.1939 geospiza_fortis ENSGFOP00000018137 86.4048 79.5317 ENSG00000107581 homo_sapiens ENSP00000358140 87.5543 80.3907 taeniopygia_guttata ENSTGUP00000011445 88.064 80.8588 ENSG00000107581 homo_sapiens ENSP00000358140 78.8712 72.2142 erpetoichthys_calabaricus ENSECRP00000023625 81.4649 74.5889 ENSG00000107581 homo_sapiens ENSP00000358140 78.5818 70.4776 kryptolebias_marmoratus ENSKMAP00000005320 85.7143 76.8745 ENSG00000107581 homo_sapiens ENSP00000358140 83.1404 75.9768 salvator_merianae ENSSMRP00000005547 86.003 78.5928 ENSG00000107581 homo_sapiens ENSP00000358140 78.5818 71.563 oryzias_javanicus ENSOJAP00000039875 86.2589 78.5544 ENSG00000107581 homo_sapiens ENSP00000358140 78.0753 70.9117 amphilophus_citrinellus ENSACIP00000003822 86.32 78.4 ENSG00000107581 homo_sapiens ENSP00000358140 77.7135 70.1881 dicentrarchus_labrax ENSDLAP00005017514 86.4734 78.0998 ENSG00000107581 homo_sapiens ENSP00000358140 78.0753 71.78 amphiprion_percula ENSAPEP00000000617 87.9381 80.8476 ENSG00000107581 homo_sapiens ENSP00000358140 82.3444 76.411 pelodiscus_sinensis ENSPSIP00000006608 90.7496 84.2105 ENSG00000107581 homo_sapiens ENSP00000358140 88.4226 82.4168 gopherus_evgoodei ENSGEVP00005028043 86.4215 80.5516 ENSG00000107581 homo_sapiens ENSP00000358140 88.4226 82.5615 chelonoidis_abingdonii ENSCABP00000012968 87.7874 81.9684 ENSG00000107581 homo_sapiens ENSP00000358140 77.4964 70.9841 seriola_dumerili ENSSDUP00000026429 86.7909 79.4976 ENSG00000107581 homo_sapiens ENSP00000358140 76.7004 68.8133 cottoperca_gobio ENSCGOP00000020822 82.8773 74.355 ENSG00000107581 homo_sapiens ENSP00000358140 85.6006 78.9436 struthio_camelus_australis ENSSCUP00000004710 89.6212 82.6515 ENSG00000107581 homo_sapiens ENSP00000358140 87.699 80.9696 anser_brachyrhynchus ENSABRP00000001237 87.5723 80.8526 ENSG00000107581 homo_sapiens ENSP00000358140 75.1809 67.8003 gasterosteus_aculeatus ENSGACP00000004184 85.0942 76.7404 ENSG00000107581 homo_sapiens ENSP00000358140 78.7265 71.1288 cynoglossus_semilaevis ENSCSEP00000012660 85.2665 77.0376 ENSG00000107581 homo_sapiens ENSP00000358140 78.8712 71.7077 poecilia_formosa ENSPFOP00000007800 85.6918 77.9088 ENSG00000107581 homo_sapiens ENSP00000358140 78.3647 71.8524 myripristis_murdjan ENSMMDP00005029671 87.7634 80.47 ENSG00000107581 homo_sapiens ENSP00000358140 76.7728 69.4645 sander_lucioperca ENSSLUP00000005952 86.4711 78.2396 ENSG00000107581 homo_sapiens ENSP00000358140 80.3184 74.602 strigops_habroptila ENSSHBP00005003080 86.7866 80.6098 ENSG00000107581 homo_sapiens ENSP00000358140 78.437 72.1418 amphiprion_ocellaris ENSAOCP00000002023 87.8444 80.7942 ENSG00000107581 homo_sapiens ENSP00000358140 87.2648 81.042 terrapene_carolina_triunguis ENSTMTP00000024423 90.2019 83.7696 ENSG00000107581 homo_sapiens ENSP00000358140 75.1809 67.7279 hucho_hucho ENSHHUP00000054874 82.9872 74.7604 ENSG00000107581 homo_sapiens ENSP00000358140 72.7207 65.5572 hucho_hucho ENSHHUP00000058918 82.4446 74.3232 ENSG00000107581 homo_sapiens ENSP00000358140 77.7858 71.2735 betta_splendens ENSBSLP00000018658 86.6237 79.3715 ENSG00000107581 homo_sapiens ENSP00000358140 80.9696 73.2272 pygocentrus_nattereri ENSPNAP00000029214 87.014 78.6936 ENSG00000107581 homo_sapiens ENSP00000358140 78.3647 71.0564 anabas_testudineus ENSATEP00000016319 87.0579 78.9389 ENSG00000107581 homo_sapiens ENSP00000358140 46.3097 33.864 ciona_savignyi ENSCSAVP00000003589 73.7327 53.917 ENSG00000107581 homo_sapiens ENSP00000358140 36.0347 19.0304 saccharomyces_cerevisiae YBR079C 51.6598 27.2822 ENSG00000107581 homo_sapiens ENSP00000358140 77.6411 71.0564 seriola_lalandi_dorsalis ENSSLDP00000026874 86.3929 79.066 ENSG00000107581 homo_sapiens ENSP00000358140 78.7988 70.9117 labrus_bergylta ENSLBEP00000030963 86.36 77.7161 ENSG00000107581 homo_sapiens ENSP00000358140 77.5687 70.1158 pundamilia_nyererei ENSPNYP00000005763 87.725 79.2962 ENSG00000107581 homo_sapiens ENSP00000358140 77.7135 70.9841 mastacembelus_armatus ENSMAMP00000021030 87.034 79.4976 ENSG00000107581 homo_sapiens ENSP00000358140 78.22 71.4906 stegastes_partitus ENSSPAP00000000374 87.6013 80.0648 ENSG00000107581 homo_sapiens ENSP00000358140 74.6744 67.4385 oncorhynchus_tshawytscha ENSOTSP00005092194 82.035 74.0859 ENSG00000107581 homo_sapiens ENSP00000358140 74.602 67.0767 oncorhynchus_tshawytscha ENSOTSP00005017956 81.1811 72.9921 ENSG00000107581 homo_sapiens ENSP00000358140 78.22 71.78 acanthochromis_polyacanthus ENSAPOP00000012069 87.2478 80.0646 ENSG00000107581 homo_sapiens ENSP00000358140 87.3372 81.1143 aquila_chrysaetos_chrysaetos ENSACCP00020011406 88.0379 81.7651 ENSG00000107581 homo_sapiens ENSP00000358140 76.7004 69.0304 nothobranchius_furzeri ENSNFUP00015054378 85.2776 76.7498 ENSG00000107581 homo_sapiens ENSP00000358140 75.6151 68.8857 cyprinodon_variegatus ENSCVAP00000003719 87.0108 79.2673 ENSG00000107581 homo_sapiens ENSP00000358140 77.9305 70.9117 denticeps_clupeoides ENSDCDP00000048540 83.618 76.087 ENSG00000107581 homo_sapiens ENSP00000358140 78.1476 71.4182 larimichthys_crocea ENSLCRP00005054008 86.3309 78.8969 ENSG00000107581 homo_sapiens ENSP00000358140 79.0883 72.1418 takifugu_rubripes ENSTRUP00000045687 86.54 78.939 ENSG00000107581 homo_sapiens ENSP00000358140 86.4689 79.0883 ficedula_albicollis ENSFALP00000002280 86.4689 79.0883 ENSG00000107581 homo_sapiens ENSP00000358140 76.411 69.2475 hippocampus_comes ENSHCOP00000003756 88.1469 79.8831 ENSG00000107581 homo_sapiens ENSP00000358140 78.0753 71.563 cyprinus_carpio_carpio ENSCCRP00000064891 86.32 79.12 ENSG00000107581 homo_sapiens ENSP00000358140 79.1606 71.7077 cyprinus_carpio_carpio ENSCCRP00000096198 85.4688 77.4219 ENSG00000107581 homo_sapiens ENSP00000358140 87.5543 81.1143 coturnix_japonica ENSCJPP00005025682 87.2386 80.8219 ENSG00000107581 homo_sapiens ENSP00000358140 78.7988 71.563 poecilia_latipinna ENSPLAP00000019325 86.36 78.4298 ENSG00000107581 homo_sapiens ENSP00000358140 62.9522 57.0188 sinocyclocheilus_grahami ENSSGRP00000022859 83.0153 75.1908 ENSG00000107581 homo_sapiens ENSP00000358140 78.437 71.6353 sinocyclocheilus_grahami ENSSGRP00000049283 87.4194 79.8387 ENSG00000107581 homo_sapiens ENSP00000358140 77.5687 70.1158 maylandia_zebra ENSMZEP00005015572 87.2964 78.9088 ENSG00000107581 homo_sapiens ENSP00000358140 65.1954 57.8871 tetraodon_nigroviridis ENSTNIP00000005545 84.127 74.6965 ENSG00000107581 homo_sapiens ENSP00000358140 67.5109 60.9262 tetraodon_nigroviridis ENSTNIP00000006423 83.7522 75.5835 ENSG00000107581 homo_sapiens ENSP00000358140 76.9899 69.3922 paramormyrops_kingsleyae ENSPKIP00000000325 87.6441 78.9951 ENSG00000107581 homo_sapiens ENSP00000358140 78.22 71.2735 scleropages_formosus ENSSFOP00015009754 87.8148 80.0163 ENSG00000107581 homo_sapiens ENSP00000358140 78.2923 70.8394 leptobrachium_leishanense ENSLLEP00000036511 77.7299 70.3305 ENSG00000107581 homo_sapiens ENSP00000358140 77.3517 69.9711 scophthalmus_maximus ENSSMAP00000021892 84.4392 76.3823 ENSG00000107581 homo_sapiens ENSP00000358140 74.4573 68.3792 oryzias_melastigma ENSOMEP00000014783 87.4257 80.2889
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0001732 involved_in formation of cytoplasmic translation initiation complex 3 IBA,IDA,NAS Homo_sapiens(9606) Process GO:0002188 involved_in translation reinitiation 1 IBA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 2 HDA,IDA Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 IBA Homo_sapiens(9606) Function GO:0003743 contributes_to translation initiation factor activity 3 IBA,IC,IDA Homo_sapiens(9606) Function GO:0005198 enables structural molecule activity 1 NAS Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 NAS Homo_sapiens(9606) Component GO:0005829 located_in cytosol 2 IDA,TAS Homo_sapiens(9606) Component GO:0005852 part_of eukaryotic translation initiation factor 3 complex 2 IDA,IPI Homo_sapiens(9606) Component GO:0005874 located_in microtubule 1 IEA Homo_sapiens(9606) Component GO:0006413 involved_in translational initiation 1 IC Homo_sapiens(9606) Process GO:0014069 located_in postsynaptic density 1 IEA Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0016282 part_of eukaryotic 43S preinitiation complex 1 IEA Homo_sapiens(9606) Component GO:0030971 enables receptor tyrosine kinase binding 1 IEA Homo_sapiens(9606) Function GO:0033290 part_of eukaryotic 48S preinitiation complex 1 IEA Homo_sapiens(9606) Component GO:0043614 part_of multi-eIF complex 1 IBA Homo_sapiens(9606) Component GO:0070373 involved_in negative regulation of ERK1 and ERK2 cascade 1 IEA Homo_sapiens(9606) Process GO:0071540 part_of eukaryotic translation initiation factor 3 complex, eIF3e 1 IBA Homo_sapiens(9606) Component GO:0071541 part_of eukaryotic translation initiation factor 3 complex, eIF3m 1 IBA Homo_sapiens(9606) Component GO:0075522 involved_in IRES-dependent viral translational initiation 1 IDA Homo_sapiens(9606) Process GO:0075525 involved_in viral translational termination-reinitiation 1 IDA Homo_sapiens(9606) Process
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