Ensembl ID ENSG00000107581 Gene ID 8661 Accession 3271
Gene Symbol EIF3A Alias EIF3;P167;p180;p185;TIF32;EIF3S10;eIF3-p170;eIF3-theta Full Name eukaryotic translation initiation factor 3 subunit A
Position 10 : 119033670 - 119080823 Length 47154 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of cytoplasmic translation initiation complex; and viral translational termination-reinitiation. Located in cytosol; nucleolus; and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000107581 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000107581 EIF3A tumors 17170115
ENSG00000107581 EIF3A colon cancer 17381544
ENSG00000107581 EIF3A tumor 17557237
ENSG00000107581 EIF3A cancer 20056645
ENSG00000107581 EIF3A cancer 20647036
ENSG00000107581 EIF3A lung cancer 20818067
ENSG00000107581 EIF3A breast cancer 21607584
ENSG00000107581 EIF3A lung cancer 21610145
ENSG00000107581 EIF3A cancers 21625209
ENSG00000107581 EIF3A tumor 22619676
ENSG00000107581 EIF3A lung cancer 23127338
ENSG00000107581 EIF3A cancer 23437357
ENSG00000107581 EIF3A lung cancer 23959654
ENSG00000107581 EIF3A cancer 24386425
ENSG00000107581 EIF3A non-small cell lung cancers 24789280
ENSG00000107581 EIF3A urinary bladder cancer 25070653
ENSG00000107581 EIF3A ovarian cancer 25544161
ENSG00000107581 EIF3A lung cancer 25732572
ENSG00000107581 EIF3A ovarian cancer 26164510
ENSG00000107581 EIF3A ovarian cancer 26213845
ENSG00000107581 EIF3A gastric cancer 27333287
ENSG00000107581 EIF3A cancer 27550487
ENSG00000107581 EIF3A tumor 28074905
ENSG00000107581 EIF3A cancers 28083147
ENSG00000107581 EIF3A tumor 28359406
ENSG00000107581 EIF3A cancer 29031564
ENSG00000107581 EIF3A Epithelial Ovarian Cancer 29581788
ENSG00000107581 EIF3A tumor 30026845
ENSG00000107581 EIF3A tumor 30340049
ENSG00000107581 EIF3A cancer 31156702
ENSG00000107581 EIF3A lung cancer 31197975
ENSG00000107581 EIF3A cancers 31218114
ENSG00000107581 EIF3A tumor 31363116
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000107581 EIF3A MESO 0.031 low
ENSG00000107581 EIF3A STAD 0.043 low
ENSG00000107581 EIF3A PAAD 0.0015 high
ENSG00000107581 EIF3A ACC 0.00042 high
ENSG00000107581 EIF3A LUSC 0.021 low
ENSG00000107581 EIF3A KIRP 0.049 high
ENSG00000107581 EIF3A KICH 0.042 high
ENSG00000107581 EIF3A LUAD 0.0095 high
ENSG00000107581 EIF3A BRCA 0.032 high
ENSG00000107581 EIF3A BLCA 0.0022 high
ENSG00000107581 EIF3A LAML 0.0019 low
ENSG00000107581 EIF3A GBM 0.003 low
ENSG00000107581 EIF3A SKCM 0.046 high
ENSG00000107581 EIF3A CESC 0.017 high
ENSG00000107581 EIF3A LIHC 0.0086 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000107581 EIF3A CHOL Del 1.158303 0.249611 0.508813 0.305556
ENSG00000107581 EIF3A LGG Del 15.671509 0.132746 0.581449 0.284600
ENSG00000107581 EIF3A COAD Del 1.572257 0.051852 0.339375 0.221729
ENSG00000107581 EIF3A GBM Del 2.532479 0.072427 0.700272 0.894281
ENSG00000107581 EIF3A LIHC Del 4.517209 0.116165 0.495402 0.286486
ENSG00000107581 EIF3A BLCA Del 0.923056 0.080933 0.390257 0.392157
ENSG00000107581 EIF3A BRCA Del 6.526256 0.100045 0.394371 0.296296
ENSG00000107581 EIF3A STAD Del 0.687314 0.060147 0.338176 0.192744
ENSG00000107581 EIF3A UCEC Del 1.447427 0.057447 0.510736 0.107607
ENSG00000107581 EIF3A MESO Del 2.360088 0.189153 0.487022 0.344828
ENSG00000107581 EIF3A OV Del 3.062271 0.220270 0.505173 0.343696