RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000100412	Gene ID	50	Accession	118
Symbol	ACO2	Alias	ICRD;OCA8;OPA9;ACONM;HEL-S-284	Full Name	aconitase 2
Status	Confidence	Length	81444 bases	Strand	Plus strand
Position	22 : 41447830 - 41529273	RNA binding domain	Aconitase , Aconitase_C
Summary	The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]