Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000100412 Gene ID 50 Accession 118
Symbol ACO2 Alias ICRD;OCA8;OPA9;ACONM;HEL-S-284 Full Name aconitase 2
Status Confidence Length 81444 bases Strand Plus strand
Position 22 : 41447830 - 41529273 RNA binding domain Aconitase , Aconitase_C
Summary The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000503590 Aconitase_C PF00694 3.7e-48 1
ENSP00000503590 Aconitase PF00330 6.4e-151 2
ENSP00000503371 Aconitase_C PF00694 3.8e-48 1
ENSP00000503371 Aconitase PF00330 6.9e-151 2
ENSP00000504453 Aconitase_C PF00694 3.8e-48 1
ENSP00000504453 Aconitase PF00330 6.9e-151 2
ENSP00000216254 Aconitase_C PF00694 4.1e-48 1
ENSP00000216254 Aconitase PF00330 7.8e-151 2
ENSP00000504684 Aconitase_C PF00694 4.1e-48 1
ENSP00000504684 Aconitase PF00330 5e-149 2
ENSP00000503471 Aconitase_C PF00694 4.3e-48 1
ENSP00000503471 Aconitase PF00330 8e-151 2
ENSP00000379769 Aconitase_C PF00694 4.3e-48 1
ENSP00000379769 Aconitase PF00330 1.6e-144 2
ENSP00000379769 Aconitase PF00330 1.6e-144 3
ENSP00000504150 Aconitase_C PF00694 4.3e-48 1
ENSP00000504150 Aconitase PF00330 1.6e-144 2
ENSP00000504150 Aconitase PF00330 1.6e-144 3
ENSP00000504513 Aconitase_C PF00694 6.5e-29 1
ENSP00000504513 Aconitase PF00330 6.2e-151 2
ENSP00000504780 Aconitase_C PF00694 6.3e-12 1
ENSP00000504780 Aconitase PF00330 6.6e-151 2
ENSP00000504377 Aconitase PF00330 3.1e-122 1
ENSP00000504719 Aconitase PF00330 1.8e-102 1
ENSP00000504634 Aconitase PF00330 1.2e-89 1
ENSP00000503370 Aconitase PF00330 5.5e-89 1
ENSP00000503990 Aconitase PF00330 4.2e-70 1
ENSP00000503709 Aconitase PF00330 2.5e-07 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36559588 Genome-Wide Identification and Expression Profiling of Aconitase Gene Family Members Reveals Their Roles in Plant Development and Adaptation to Diverse Stress in Triticum aestivum L. Singh Mahipal Kesawat 2022-12-12 Plants (Basel, Switzerland)
28819260 Thermodynamic and Kinetic Analyses of Iron Response Element (IRE)-mRNA Binding to Iron Regulatory Protein, IRP1. A Mateen Khan 2017-08-17 Scientific reports
27452465 The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease. Yalin Liao 2016-08-02 Cell reports

Transcripts

Name Transcript ID bp Protein Translation ID
ACO2-209 ENST00000676748 3170 747aa ENSP00000503371
ACO2-225 ENST00000678600 3230 No protein -
ACO2-220 ENST00000677554 2563 716aa ENSP00000504513
ACO2-232 ENST00000679320 2819 731aa ENSP00000504780
ACO2-223 ENST00000678394 3712 No protein -
ACO2-224 ENST00000678454 2501 No protein -
ACO2-216 ENST00000677427 1707 No protein -
ACO2-203 ENST00000466237 1460 422aa ENSP00000504719
ACO2-201 ENST00000216254 2734 780aa ENSP00000216254
ACO2-208 ENST00000676714 2895 80aa ENSP00000504699
ACO2-226 ENST00000678688 3130 288aa ENSP00000503990
ACO2-218 ENST00000677516 3401 324aa ENSP00000503370
ACO2-227 ENST00000678788 3012 775aa ENSP00000504684
ACO2-214 ENST00000677007 2777 324aa ENSP00000504634
ACO2-213 ENST00000676959 2948 487aa ENSP00000504377
ACO2-231 ENST00000679311 3244 No protein -
ACO2-210 ENST00000676792 3355 725aa ENSP00000503590
ACO2-215 ENST00000677153 3237 747aa ENSP00000504453
ACO2-228 ENST00000678819 3164 92aa ENSP00000503199
ACO2-202 ENST00000396512 2811 805aa ENSP00000379769
ACO2-222 ENST00000678269 2811 805aa ENSP00000504150
ACO2-219 ENST00000677532 3037 788aa ENSP00000503471
ACO2-204 ENST00000471094 699 No protein -
ACO2-229 ENST00000679264 3978 No protein -
ACO2-221 ENST00000677698 3376 69aa ENSP00000503913
ACO2-211 ENST00000676822 3251 No protein -
ACO2-207 ENST00000676664 3066 160aa ENSP00000503709
ACO2-206 ENST00000482208 624 No protein -
ACO2-205 ENST00000478010 644 No protein -
ACO2-217 ENST00000677492 3956 No protein -
ACO2-230 ENST00000679284 2890 No protein -
ACO2-212 ENST00000676883 3016 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
61634Crohn Disease2E-1026192919
82921Inflammatory Bowel Diseases3E-626192919

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000100412homo_sapiensENSP0000030947740.944925.7593homo_sapiensENSP0000021625446.666729.359
ENSG00000100412homo_sapiensENSP0000025888637.279322.3261homo_sapiensENSP0000021625446.025627.5641

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000100412homo_sapiensENSP0000021625498.076997.4359nomascus_leucogenysENSNLEP0000001884495.62595
ENSG00000100412homo_sapiensENSP0000021625498.461598.3333pan_paniscusENSPPAP000000047409695.875
ENSG00000100412homo_sapiensENSP0000021625499.35998.9744pongo_abeliiENSPPYP0000001324896.273395.9006
ENSG00000100412homo_sapiensENSP0000021625498.461598.3333pan_troglodytesENSPTRP000000248539695.875
ENSG00000100412homo_sapiensENSP0000021625499.743699.7436gorilla_gorillaENSGGOP0000000109299.743699.7436
ENSG00000100412homo_sapiensENSP0000021625496.923193.0769ornithorhynchus_anatinusENSOANP0000000562896.183292.3664
ENSG00000100412homo_sapiensENSP0000021625497.051394.6154sarcophilus_harrisiiENSSHAP0000001175496.556194.1327
ENSG00000100412homo_sapiensENSP0000021625483.589781.6667notamacropus_eugeniiENSMEUP0000000186084.45682.513
ENSG00000100412homo_sapiensENSP0000021625463.205161.1538choloepus_hoffmanniENSCHOP0000000315172.92970.5621
ENSG00000100412homo_sapiensENSP0000021625491.923187.5641dasypus_novemcinctusENSDNOP0000001408691.221486.8957
ENSG00000100412homo_sapiensENSP0000021625489.871887.4359erinaceus_europaeusENSEEUP0000000931789.756787.3239
ENSG00000100412homo_sapiensENSP0000021625474.615471.7949echinops_telfairiENSETEP0000000872575.096872.2581
ENSG00000100412homo_sapiensENSP0000021625497.948797.1795cercocebus_atysENSCATP0000001278495.859595.1067
ENSG00000100412homo_sapiensENSP0000021625496.153894.4872macaca_fascicularisENSMFAP0000005887984.175182.716
ENSG00000100412homo_sapiensENSP0000021625496.153894.4872macaca_mulattaENSMMUP0000005792084.175182.716
ENSG00000100412homo_sapiensENSP0000021625497.948797.1795macaca_nemestrinaENSMNEP0000004388395.619594.8686
ENSG00000100412homo_sapiensENSP0000021625491.923190.2564papio_anubisENSPANP0000002435883.566482.0513
ENSG00000100412homo_sapiensENSP0000021625497.948797.3077mandrillus_leucophaeusENSMLEP0000001525395.619594.9937
ENSG00000100412homo_sapiensENSP0000021625495.384693.5897tursiops_truncatusENSTTRP0000000316092.768191.0224
ENSG00000100412homo_sapiensENSP0000021625498.717996.5385vulpes_vulpesENSVVUP0000000461098.591696.4149
ENSG00000100412homo_sapiensENSP0000021625498.717996.7949mus_spretusMGP_SPRETEiJ_P004094798.717996.7949
ENSG00000100412homo_sapiensENSP0000021625498.589797.0513equus_asinusENSEASP0000505644793.325291.8689
ENSG00000100412homo_sapiensENSP0000021625498.589796.4103capra_hircusENSCHIP0000000394798.589796.4103
ENSG00000100412homo_sapiensENSP0000021625498.589796.5385loxodonta_africanaENSLAFP0000000506098.716396.6624
ENSG00000100412homo_sapiensENSP0000021625498.846297.1795panthera_leoENSPLOP0000001736698.719697.0551
ENSG00000100412homo_sapiensENSP0000021625498.076996.0256ailuropoda_melanoleucaENSAMEP0000002539587.328885.5023
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667bos_indicus_hybridENSBIXP0000502769698.589796.6667
ENSG00000100412homo_sapiensENSP0000021625498.846297.0513oryctolagus_cuniculusENSOCUP0000002085096.616594.8622
ENSG00000100412homo_sapiensENSP0000021625497.948795.5128equus_caballusENSECAP0000006200894.088791.7488
ENSG00000100412homo_sapiensENSP0000021625497.692395.2564canis_lupus_familiarisENSCAFP0084502361494.306991.9554
ENSG00000100412homo_sapiensENSP0000021625498.205196.6667panthera_pardusENSPPRP0000001243195.392393.8979
ENSG00000100412homo_sapiensENSP0000021625494.487292.9487marmota_marmota_marmotaENSMMMP0000000417298.926297.3154
ENSG00000100412homo_sapiensENSP0000021625498.589796.5385balaenoptera_musculusENSBMSP0001001917198.463596.4149
ENSG00000100412homo_sapiensENSP0000021625498.846297.0513cavia_porcellusENSCPOP0000002261898.846297.0513
ENSG00000100412homo_sapiensENSP0000021625498.846297.1795felis_catusENSFCAP0000001590898.719697.0551
ENSG00000100412homo_sapiensENSP0000021625498.974497.0513ursus_americanusENSUAMP0000002930896.620894.7434
ENSG00000100412homo_sapiensENSP0000021625497.820594.359monodelphis_domesticaENSMODP0000002067597.570394.1176
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667bison_bison_bisonENSBBBP0000000884698.589796.6667
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667monodon_monocerosENSMMNP0001502451895.409493.5484
ENSG00000100412homo_sapiensENSP0000021625498.846297.0513sus_scrofaENSSSCP0000007630398.846297.0513
ENSG00000100412homo_sapiensENSP0000021625492.564189.6154microcebus_murinusENSMICP0000001234894.379191.3726
ENSG00000100412homo_sapiensENSP0000021625498.461596.5385octodon_degusENSODEP0000001703198.461596.5385
ENSG00000100412homo_sapiensENSP0000021625476.666774.6154jaculus_jaculusENSJJAP0000001047894.920692.381
ENSG00000100412homo_sapiensENSP0000021625492.179588.7179ovis_aries_rambouilletENSOARP0002003175086.835783.5749
ENSG00000100412homo_sapiensENSP0000021625498.974497.0513ursus_maritimusENSUMAP0000002896498.847696.927
ENSG00000100412homo_sapiensENSP0000021625498.076996.4103ochotona_princepsENSOPRP0000000033497.204695.5527
ENSG00000100412homo_sapiensENSP0000021625495.128292.4359delphinapterus_leucasENSDLEP0000002238084.606682.2121
ENSG00000100412homo_sapiensENSP0000021625497.051395.3846physeter_catodonENSPCTP0000502459798.439596.749
ENSG00000100412homo_sapiensENSP0000021625498.717996.7949mus_caroliMGP_CAROLIEiJ_P003914398.717996.7949
ENSG00000100412homo_sapiensENSP0000021625498.846296.7949mus_musculusENSMUSP0000002311698.846296.7949
ENSG00000100412homo_sapiensENSP0000021625497.820595.2564dipodomys_ordiiENSDORP0000000207398.451695.871
ENSG00000100412homo_sapiensENSP0000021625498.846297.1795mustela_putorius_furoENSMPUP0000001629298.719697.0551
ENSG00000100412homo_sapiensENSP0000021625498.205196.1538aotus_nancymaaeENSANAP0000002323895.392393.3997
ENSG00000100412homo_sapiensENSP0000021625480.64179.1026saimiri_boliviensis_boliviensisENSSBOP0000000967198.127996.2559
ENSG00000100412homo_sapiensENSP0000021625490.512888.3333saimiri_boliviensis_boliviensisENSSBOP0000002520392.408490.1832
ENSG00000100412homo_sapiensENSP0000021625451.282149.4872vicugna_pacosENSVPAP0000000241752.770450.9235
ENSG00000100412homo_sapiensENSP0000021625499.35998.7179chlorocebus_sabaeusENSCSAP0000000211599.35998.7179
ENSG00000100412homo_sapiensENSP0000021625498.333396.7949tupaia_belangeriENSTBEP0000000960198.333396.7949
ENSG00000100412homo_sapiensENSP0000021625498.846296.9231mesocricetus_auratusENSMAUP0000000553998.846296.9231
ENSG00000100412homo_sapiensENSP0000021625498.717997.0513phocoena_sinusENSPSNP0000000949895.533593.9206
ENSG00000100412homo_sapiensENSP0000021625498.717997.0513camelus_dromedariusENSCDRP0000502505196.855395.2201
ENSG00000100412homo_sapiensENSP0000021625497.564195.5128carlito_syrichtaENSTSYP0000002296297.190395.1469
ENSG00000100412homo_sapiensENSP0000021625498.717997.0513panthera_tigris_altaicaENSPTIP0000001575998.591696.927
ENSG00000100412homo_sapiensENSP0000021625498.589796.4103rattus_norvegicusENSRNOP0000002914498.589796.4103
ENSG00000100412homo_sapiensENSP0000021625497.948796.4103prolemur_simusENSPSMP0000000188989.988288.5748
ENSG00000100412homo_sapiensENSP0000021625498.846296.6667microtus_ochrogasterENSMOCP0000000839898.846296.6667
ENSG00000100412homo_sapiensENSP0000021625454.871853.2051sorex_araneusENSSARP0000000402454.871853.2051
ENSG00000100412homo_sapiensENSP0000021625498.846297.1795peromyscus_maniculatus_bairdiiENSPEMP0000002440998.846297.1795
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667bos_mutusENSBMUP0000002180298.589796.6667
ENSG00000100412homo_sapiensENSP0000021625498.717996.9231mus_spicilegusENSMSIP0000002917198.717996.9231
ENSG00000100412homo_sapiensENSP0000021625486.153883.9744cricetulus_griseus_chok1gshdENSCGRP0000100723089.839687.5668
ENSG00000100412homo_sapiensENSP0000021625497.948795.8974cricetulus_griseus_chok1gshdENSCGRP0000102590396.954394.9239
ENSG00000100412homo_sapiensENSP0000021625498.205196.1538pteropus_vampyrusENSPVAP0000000109695.155393.1677
ENSG00000100412homo_sapiensENSP0000021625496.153893.0769myotis_lucifugusENSMLUP0000000225197.024693.9198
ENSG00000100412homo_sapiensENSP0000021625495.512892.3077vombatus_ursinusENSVURP0001000206495.025591.8367
ENSG00000100412homo_sapiensENSP0000021625498.846296.5385rhinolophus_ferrumequinumENSRFEP0001002710398.846296.5385
ENSG00000100412homo_sapiensENSP0000021625498.846297.1795neovison_visonENSNVIP0000000049198.719697.0551
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667bos_taurusENSBTAP0000000843198.589796.6667
ENSG00000100412homo_sapiensENSP0000021625498.461596.1538heterocephalus_glaber_femaleENSHGLP0000002163896.847494.5776
ENSG00000100412homo_sapiensENSP0000021625488.461587.9487rhinopithecus_bietiENSRBIP0000002244695.833395.2778
ENSG00000100412homo_sapiensENSP0000021625498.717996.5385canis_lupus_dingoENSCAFP0002000231098.591696.4149
ENSG00000100412homo_sapiensENSP0000021625498.974497.4359sciurus_vulgarisENSSVLP0000502649798.974497.4359
ENSG00000100412homo_sapiensENSP0000021625495.384692.9487phascolarctos_cinereusENSPCIP0000003573895.140792.711
ENSG00000100412homo_sapiensENSP0000021625498.076996.4103procavia_capensisENSPCAP0000000914696.226494.5912
ENSG00000100412homo_sapiensENSP0000021625497.179594.6154nannospalax_galiliENSNGAP0000001459997.554794.9807
ENSG00000100412homo_sapiensENSP0000021625474.871871.0256nannospalax_galiliENSNGAP0000001211390.542685.8915
ENSG00000100412homo_sapiensENSP0000021625497.820595.641bos_grunniensENSBGRP0000001266587.585.5505
ENSG00000100412homo_sapiensENSP0000021625498.589796.4103chinchilla_lanigeraENSCLAP0000002476298.589796.4103
ENSG00000100412homo_sapiensENSP0000021625498.717996.9231cervus_hanglu_yarkandensisENSCHYP0000003369498.717996.9231
ENSG00000100412homo_sapiensENSP0000021625498.974496.7949catagonus_wagneriENSCWAP0000001550098.847696.6709
ENSG00000100412homo_sapiensENSP0000021625498.846297.3077ictidomys_tridecemlineatusENSSTOP0000002850098.846297.3077
ENSG00000100412homo_sapiensENSP0000021625488.974486.1538otolemur_garnettiiENSOGAP0000000254992.656989.7196
ENSG00000100412homo_sapiensENSP0000021625498.461596.9231cebus_imitatorENSCCAP0000002154395.641394.1469
ENSG00000100412homo_sapiensENSP0000021625498.461596.6667urocitellus_parryiiENSUPAP0001000737475.516274.1396
ENSG00000100412homo_sapiensENSP0000021625498.717997.0513moschus_moschiferusENSMMSP0000001793698.717997.0513
ENSG00000100412homo_sapiensENSP0000021625498.589797.6923rhinopithecus_roxellanaENSRROP0000000165295.646894.7761
ENSG00000100412homo_sapiensENSP0000021625498.589796.6667mus_pahariMGP_PahariEiJ_P004249398.589796.6667
ENSG00000100412homo_sapiensENSP0000021625497.307795.8974propithecus_coquereliENSPCOP0000001195595.471794.0881
ENSG00000100412homo_sapiensENSP0000021625482.564172.5641caenorhabditis_elegansF54H12.1a.182.882972.8443
ENSG00000100412homo_sapiensENSP000002162548069.1026drosophila_melanogasterFBpp008181279.693568.8378
ENSG00000100412homo_sapiensENSP0000021625482.307771.7949drosophila_melanogasterFBpp031217881.575671.1563
ENSG00000100412homo_sapiensENSP0000021625445.897439.6154ciona_intestinalisENSCINP0000001821785.645973.9234
ENSG00000100412homo_sapiensENSP0000021625438.076933.4615ciona_intestinalisENSCINP0000001821685.590875.2161
ENSG00000100412homo_sapiensENSP0000021625472.948764.4872eptatretus_burgeriENSEBUP0000001470490.174379.7147
ENSG00000100412homo_sapiensENSP0000021625489.35980callorhinchus_miliiENSCMIP0000001038085.837476.8473
ENSG00000100412homo_sapiensENSP0000021625469.743664.7436latimeria_chalumnaeENSLACP0000001346686.624280.414
ENSG00000100412homo_sapiensENSP0000021625473.461564.6154lepisosteus_oculatusENSLOCP0000001426981.276671.4894
ENSG00000100412homo_sapiensENSP0000021625488.461579.1026clupea_harengusENSCHAP0000001707586.792477.6101
ENSG00000100412homo_sapiensENSP0000021625489.615480.1282clupea_harengusENSCHAP0000003453986.832377.6398
ENSG00000100412homo_sapiensENSP0000021625490.769283.0769danio_rerioENSDARP0000012388389.620382.0253
ENSG00000100412homo_sapiensENSP0000021625490.64181.9231carassius_auratusENSCARP0000001554390.409281.7136
ENSG00000100412homo_sapiensENSP0000021625490.384682.0513carassius_auratusENSCARP0000006211787.577679.5031
ENSG00000100412homo_sapiensENSP0000021625491.025682.4359astyanax_mexicanusENSAMXP0000000905490.792882.2251
ENSG00000100412homo_sapiensENSP0000021625476.282168.2051astyanax_mexicanusENSAMXP0000001597586.734777.551
ENSG00000100412homo_sapiensENSP0000021625490.769281.9231ictalurus_punctatusENSIPUP0000000163990.65381.8182
ENSG00000100412homo_sapiensENSP0000021625487.564178.7179esox_luciusENSELUP0000002048885.481876.8461
ENSG00000100412homo_sapiensENSP0000021625490.256480.641esox_luciusENSELUP0000003054585.540776.4277
ENSG00000100412homo_sapiensENSP0000021625489.487278.9744electrophorus_electricusENSEEEP0000005229188.131377.7778
ENSG00000100412homo_sapiensENSP0000021625490.897482.0513electrophorus_electricusENSEEEP0000002295390.66581.8414
ENSG00000100412homo_sapiensENSP0000021625488.333380.1282oncorhynchus_kisutchENSOKIP0000501022686.994978.9141
ENSG00000100412homo_sapiensENSP0000021625488.461579.7436oncorhynchus_kisutchENSOKIP0000511738480.232672.3256
ENSG00000100412homo_sapiensENSP0000021625488.846280.3846oncorhynchus_kisutchENSOKIP0000503306482.206474.3772
ENSG00000100412homo_sapiensENSP0000021625489.35981.0256oncorhynchus_kisutchENSOKIP0000501960485.312177.3562
ENSG00000100412homo_sapiensENSP0000021625489.102680.5128oncorhynchus_mykissENSOMYP0000007872884.038775.9371
ENSG00000100412homo_sapiensENSP0000021625487.948779.359oncorhynchus_mykissENSOMYP0000003608285.857377.4718
ENSG00000100412homo_sapiensENSP0000021625488.461580.2564oncorhynchus_mykissENSOMYP0000010045487.121279.0404
ENSG00000100412homo_sapiensENSP0000021625488.846280.3846oncorhynchus_mykissENSOMYP0000001662182.894775
ENSG00000100412homo_sapiensENSP0000021625484.743677.1795salmo_salarENSSSAP0000000471182.41975.0623
ENSG00000100412homo_sapiensENSP0000021625489.743681.1538salmo_salarENSSSAP0000013887186.526678.2447
ENSG00000100412homo_sapiensENSP0000021625489.487281.0256salmo_salarENSSSAP0000008232985.854977.7368
ENSG00000100412homo_sapiensENSP0000021625487.179578.8462salmo_salarENSSSAP0000012355585.106476.9712
ENSG00000100412homo_sapiensENSP0000021625488.589780.3846salmo_truttaENSSTUP0000008113886.918278.8679
ENSG00000100412homo_sapiensENSP0000021625488.846280.5128salmo_truttaENSSTUP0000007195786.62578.5
ENSG00000100412homo_sapiensENSP0000021625487.051378.5897salmo_truttaENSSTUP0000007960885.840777.4968
ENSG00000100412homo_sapiensENSP0000021625489.35980.8974salmo_truttaENSSTUP0000006266285.943377.8052
ENSG00000100412homo_sapiensENSP0000021625488.076978.3333gadus_morhuaENSGMOP0000004745280.633871.7136
ENSG00000100412homo_sapiensENSP0000021625485.769275.7692gadus_morhuaENSGMOP0000005395383.520673.7828
ENSG00000100412homo_sapiensENSP0000021625489.743679.4872fundulus_heteroclitusENSFHEP0000001125389.514179.2839
ENSG00000100412homo_sapiensENSP0000021625487.948778.5897fundulus_heteroclitusENSFHEP0000003343486.945577.6933
ENSG00000100412homo_sapiensENSP0000021625487.692378.2051poecilia_reticulataENSPREP0000002605888.60179.0155
ENSG00000100412homo_sapiensENSP0000021625488.974478.7179poecilia_reticulataENSPREP0000003053588.633578.4163
ENSG00000100412homo_sapiensENSP0000021625489.102679.359xiphophorus_maculatusENSXMAP0000003455388.874779.156
ENSG00000100412homo_sapiensENSP0000021625487.179577.3077xiphophorus_maculatusENSXMAP0000000069186.956577.11
ENSG00000100412homo_sapiensENSP0000021625489.743679.7436oryzias_latipesENSORLP0000000326489.628779.6415
ENSG00000100412homo_sapiensENSP0000021625485.128275.641cyclopterus_lumpusENSCLMP000050089628373.75
ENSG00000100412homo_sapiensENSP0000021625489.230879.359cyclopterus_lumpusENSCLMP0000504949587.989978.2554
ENSG00000100412homo_sapiensENSP0000021625490.128279.6154oreochromis_niloticusENSONIP0000003103384.393874.5498
ENSG00000100412homo_sapiensENSP0000021625489.615479.7436haplochromis_burtoniENSHBUP0000000284689.386279.5396
ENSG00000100412homo_sapiensENSP0000021625489.615479.7436astatotilapia_callipteraENSACLP0000002832489.386279.5396
ENSG00000100412homo_sapiensENSP0000021625486.794976.2821sparus_aurataENSSAUP0001000757783.169573.0958
ENSG00000100412homo_sapiensENSP0000021625488.205178.7179sparus_aurataENSSAUP0001003149879.721971.1472
ENSG00000100412homo_sapiensENSP0000021625476.923169.4872lates_calcariferENSLCAP0001000025389.686181.0164
ENSG00000100412homo_sapiensENSP0000021625490.897481.2821lates_calcariferENSLCAP0001002521488.40479.0524
ENSG00000100412homo_sapiensENSP0000021625494.102688.3333xenopus_tropicalisENSXETP0000001508193.982188.2202
ENSG00000100412homo_sapiensENSP0000021625496.410391.9231chrysemys_picta_belliiENSCPBP0000002913496.040991.5709
ENSG00000100412homo_sapiensENSP0000021625495.384688.2051sphenodon_punctatusENSSPUP0000001502595.019287.8672
ENSG00000100412homo_sapiensENSP0000021625495.897490.3846crocodylus_porosusENSCPRP0000502752595.5390.0383
ENSG00000100412homo_sapiensENSP0000021625495.384689.6154laticauda_laticaudataENSLLTP0000001588695.019289.272
ENSG00000100412homo_sapiensENSP0000021625495.512889.7436notechis_scutatusENSNSUP0000000469195.146989.3997
ENSG00000100412homo_sapiensENSP0000021625495.512889.7436pseudonaja_textilisENSPTXP0000000213895.146989.3997
ENSG00000100412homo_sapiensENSP0000021625492.948788.2051anas_platyrhynchos_platyrhynchosENSAPLP0000002678687.560483.0918
ENSG00000100412homo_sapiensENSP0000021625496.282191.5385gallus_gallusENSGALP0001001767495.668890.9554
ENSG00000100412homo_sapiensENSP0000021625493.076988.5897meleagris_gallopavoENSMGAP0000002885190.7586.375
ENSG00000100412homo_sapiensENSP0000021625496.282191.5385serinus_canariaENSSCAP0000000724795.668890.9554
ENSG00000100412homo_sapiensENSP0000021625492.307787.1795parus_majorENSPMJP0000000513291.836786.7347
ENSG00000100412homo_sapiensENSP0000021625496.153890.3846anolis_carolinensisENSACAP0000000463895.785490.0383
ENSG00000100412homo_sapiensENSP0000021625489.487279.8718neolamprologus_brichardiENSNBRP0000000609789.258379.6675
ENSG00000100412homo_sapiensENSP0000021625495.64189.7436naja_najaENSNNAP0000000658895.274689.3997
ENSG00000100412homo_sapiensENSP0000021625490.384684.359podarcis_muralisENSPMRP0000003215286.080680.3419
ENSG00000100412homo_sapiensENSP0000021625492.948788.8462geospiza_fortisENSGFOP0000001151596.666792.4
ENSG00000100412homo_sapiensENSP0000021625496.282191.2821taeniopygia_guttataENSTGUP0000001024795.668890.7006
ENSG00000100412homo_sapiensENSP0000021625492.051382.9487erpetoichthys_calabaricusENSECRP0000002372291.698682.6309
ENSG00000100412homo_sapiensENSP0000021625454.230847.3077kryptolebias_marmoratusENSKMAP0000002972387.941876.7152
ENSG00000100412homo_sapiensENSP0000021625490.384680.1282kryptolebias_marmoratusENSKMAP0000001997190.268980.0256
ENSG00000100412homo_sapiensENSP0000021625495.769290.641salvator_merianaeENSSMRP0000001968395.402390.2937
ENSG00000100412homo_sapiensENSP0000021625490.128280.2564oryzias_javanicusENSOJAP0000001027190.012880.1536
ENSG00000100412homo_sapiensENSP000002162547567.5641amphilophus_citrinellusENSACIP0000002793890.277881.3272
ENSG00000100412homo_sapiensENSP0000021625488.974479.8718dicentrarchus_labraxENSDLAP0000501882988.407679.3631
ENSG00000100412homo_sapiensENSP0000021625489.615479.359dicentrarchus_labraxENSDLAP0000504421789.386279.156
ENSG00000100412homo_sapiensENSP0000021625490.256481.0256amphiprion_perculaENSAPEP0000001745190.140880.9219
ENSG00000100412homo_sapiensENSP0000021625490.128279.7436amphiprion_perculaENSAPEP0000002846689.897779.5396
ENSG00000100412homo_sapiensENSP0000021625496.410391.2821pelodiscus_sinensisENSPSIP0000000804196.040990.9323
ENSG00000100412homo_sapiensENSP0000021625496.410391.5385gopherus_evgoodeiENSGEVP0000500319996.040991.1877
ENSG00000100412homo_sapiensENSP0000021625495.128290.641chelonoidis_abingdoniiENSCABP0000003132993.805389.3805
ENSG00000100412homo_sapiensENSP0000021625490.256480.641seriola_dumeriliENSSDUP0000002050190.140880.5378
ENSG00000100412homo_sapiensENSP000002162549079.4872seriola_dumeriliENSSDUP0000001102589.769879.2839
ENSG00000100412homo_sapiensENSP0000021625489.487279.359cottoperca_gobioENSCGOP0000002100484.503674.9395
ENSG00000100412homo_sapiensENSP0000021625488.717977.4359cottoperca_gobioENSCGOP0000002567787.484276.359
ENSG00000100412homo_sapiensENSP0000021625495.256490.641struthio_camelus_australisENSSCUP0000000110995.378790.7574
ENSG00000100412homo_sapiensENSP0000021625492.564188.2051anser_brachyrhynchusENSABRP0000000503887.092982.9916
ENSG00000100412homo_sapiensENSP000002162549079.8718gasterosteus_aculeatusENSGACP0000001009990.115579.9743
ENSG00000100412homo_sapiensENSP0000021625488.974478.7179gasterosteus_aculeatusENSGACP0000000629588.407678.2166
ENSG00000100412homo_sapiensENSP0000021625473.717965.1282cynoglossus_semilaevisENSCSEP0000003195486.466276.391
ENSG00000100412homo_sapiensENSP000002162549081.4103cynoglossus_semilaevisENSCSEP0000001044389.884881.306
ENSG00000100412homo_sapiensENSP000002162549080.2564poecilia_formosaENSPFOP0000001395489.655279.9489
ENSG00000100412homo_sapiensENSP0000021625489.35979.359poecilia_formosaENSPFOP0000001686689.130479.156
ENSG00000100412homo_sapiensENSP0000021625489.487279.2308myripristis_murdjanENSMMDP0000501498388.804178.626
ENSG00000100412homo_sapiensENSP0000021625485.897477.0513myripristis_murdjanENSMMDP0000500338385.459276.6582
ENSG00000100412homo_sapiensENSP0000021625488.846278.4615sander_luciopercaENSSLUP0000006087885.980175.9305
ENSG00000100412homo_sapiensENSP0000021625489.230879.359sander_luciopercaENSSLUP0000005459081.498872.4824
ENSG00000100412homo_sapiensENSP0000021625496.025691.2821strigops_habroptilaENSSHBP0000500455795.41490.7006
ENSG00000100412homo_sapiensENSP0000021625489.615480.3846amphiprion_ocellarisENSAOCP0000001435789.386280.179
ENSG00000100412homo_sapiensENSP0000021625490.256479.7436amphiprion_ocellarisENSAOCP0000003011090.025679.5396
ENSG00000100412homo_sapiensENSP0000021625496.410391.9231terrapene_carolina_triunguisENSTMTP0000000439996.040991.5709
ENSG00000100412homo_sapiensENSP0000021625488.076979.6154hucho_huchoENSHHUP0000008103587.627579.2092
ENSG00000100412homo_sapiensENSP0000021625489.35980.8974hucho_huchoENSHHUP0000006374589.473781.0013
ENSG00000100412homo_sapiensENSP0000021625489.230880.8974hucho_huchoENSHHUP0000009145289.922581.5246
ENSG00000100412homo_sapiensENSP0000021625487.692379.4872hucho_huchoENSHHUP0000002024587.917779.6915
ENSG00000100412homo_sapiensENSP0000021625488.589779.2308betta_splendensENSBSLP0000003717089.623980.1556
ENSG00000100412homo_sapiensENSP0000021625487.179577.9487betta_splendensENSBSLP0000003427590.185780.6366
ENSG00000100412homo_sapiensENSP0000021625489.102679.359betta_splendensENSBSLP0000004545687.20277.6663
ENSG00000100412homo_sapiensENSP0000021625490.256481.0256pygocentrus_nattereriENSPNAP0000002823590.025680.8184
ENSG00000100412homo_sapiensENSP0000021625489.743680.2564anabas_testudineusENSATEP0000000920388.383879.0404
ENSG00000100412homo_sapiensENSP0000021625489.615480.5128anabas_testudineusENSATEP0000006015787.703978.7955
ENSG00000100412homo_sapiensENSP0000021625489.743680.2564anabas_testudineusENSATEP0000006875788.383879.0404
ENSG00000100412homo_sapiensENSP0000021625483.974474.4872ciona_savignyiENSCSAVP0000001291279.975670.9402
ENSG00000100412homo_sapiensENSP0000021625478.717965.7692saccharomyces_cerevisiaeYLR304C78.920365.9383
ENSG00000100412homo_sapiensENSP000002162549080.5128seriola_lalandi_dorsalisENSSLDP0000002338389.884880.4097
ENSG00000100412homo_sapiensENSP000002162549079.4872seriola_lalandi_dorsalisENSSLDP0000001202389.769879.2839
ENSG00000100412homo_sapiensENSP0000021625489.35978.4615labrus_bergyltaENSLBEP0000000264889.130478.2609
ENSG00000100412homo_sapiensENSP0000021625489.35979.6154pundamilia_nyerereiENSPNYP0000000572289.130479.4118
ENSG00000100412homo_sapiensENSP0000021625488.717978.2051mastacembelus_armatusENSMAMP0000005867685.012374.9386
ENSG00000100412homo_sapiensENSP0000021625489.615480.1282mastacembelus_armatusENSMAMP0000005075485.34876.3126
ENSG00000100412homo_sapiensENSP0000021625490.256479.359stegastes_partitusENSSPAP0000003060690.025679.156
ENSG00000100412homo_sapiensENSP0000021625489.871881.0256stegastes_partitusENSSPAP0000002375889.756780.9219
ENSG00000100412homo_sapiensENSP0000021625488.717980.641oncorhynchus_tshawytschaENSOTSP0000503708886.608378.7234
ENSG00000100412homo_sapiensENSP0000021625485.897476.7949oncorhynchus_tshawytschaENSOTSP0000509742582.208673.4969
ENSG00000100412homo_sapiensENSP0000021625489.743681.4103oncorhynchus_tshawytschaENSOTSP0000506578087.173179.0785
ENSG00000100412homo_sapiensENSP0000021625488.717980.1282oncorhynchus_tshawytschaENSOTSP0000501696685.432177.1605
ENSG00000100412homo_sapiensENSP0000021625490.128279.8718acanthochromis_polyacanthusENSAPOP0000001478289.897779.6675
ENSG00000100412homo_sapiensENSP0000021625489.743679.8718acanthochromis_polyacanthusENSAPOP0000000916889.858879.9743
ENSG00000100412homo_sapiensENSP0000021625496.282191.7949aquila_chrysaetos_chrysaetosENSACCP0002001612195.668891.2102
ENSG00000100412homo_sapiensENSP0000021625489.615479.6154nothobranchius_furzeriENSNFUP0001503978289.500679.5134
ENSG00000100412homo_sapiensENSP0000021625475.128266.9231nothobranchius_furzeriENSNFUP0001501962285.923876.5396
ENSG00000100412homo_sapiensENSP0000021625490.256480.1282cyprinodon_variegatusENSCVAP0000000885790.140880.0256
ENSG00000100412homo_sapiensENSP0000021625484.102673.8462cyprinodon_variegatusENSCVAP0000000473088.17277.4194
ENSG00000100412homo_sapiensENSP0000021625490.256481.6667denticeps_clupeoidesENSDCDP0000002837490.025681.4578
ENSG00000100412homo_sapiensENSP0000021625490.256481.6667denticeps_clupeoidesENSDCDP0000001822786.168977.9682
ENSG00000100412homo_sapiensENSP0000021625488.589778.4615larimichthys_croceaENSLCRP0000501901687.690477.665
ENSG00000100412homo_sapiensENSP0000021625486.410376.6667larimichthys_croceaENSLCRP0000503554585.424675.7921
ENSG00000100412homo_sapiensENSP0000021625488.076978.0769takifugu_rubripesENSTRUP0000007448387.404677.4809
ENSG00000100412homo_sapiensENSP0000021625496.025691.4103ficedula_albicollisENSFALP0000002455095.41490.828
ENSG00000100412homo_sapiensENSP000002162549080.7692hippocampus_comesENSHCOP0000002060989.884880.6658
ENSG00000100412homo_sapiensENSP000002162549079.8718hippocampus_comesENSHCOP0000002243889.769879.6675
ENSG00000100412homo_sapiensENSP0000021625490.769282.3077cyprinus_carpio_carpioENSCCRP0000005460090.537182.0972
ENSG00000100412homo_sapiensENSP0000021625490.512882.0513cyprinus_carpio_carpioENSCCRP0000005396890.05181.6327
ENSG00000100412homo_sapiensENSP0000021625496.410391.5385coturnix_japonicaENSCJPP0000501045195.796290.9554
ENSG00000100412homo_sapiensENSP0000021625490.128280.1282poecilia_latipinnaENSPLAP0000001386690.012880.0256
ENSG00000100412homo_sapiensENSP0000021625489.102678.9744poecilia_latipinnaENSPLAP0000000046688.874778.7724
ENSG00000100412homo_sapiensENSP0000021625490.384681.9231sinocyclocheilus_grahamiENSSGRP0000010661987.795879.5766
ENSG00000100412homo_sapiensENSP0000021625489.102681.2821sinocyclocheilus_grahamiENSSGRP0000007247186.658479.0524
ENSG00000100412homo_sapiensENSP0000021625489.615479.7436maylandia_zebraENSMZEP0000502572689.386279.5396
ENSG00000100412homo_sapiensENSP0000021625489.102679.1026tetraodon_nigroviridisENSTNIP0000001591888.874778.9003
ENSG00000100412homo_sapiensENSP0000021625482.435973.7179paramormyrops_kingsleyaeENSPKIP0000001697284.716775.7576
ENSG00000100412homo_sapiensENSP0000021625490.256481.5385paramormyrops_kingsleyaeENSPKIP0000002589490.025681.3299
ENSG00000100412homo_sapiensENSP0000021625490.128281.2821scleropages_formosusENSSFOP0001504214588.205879.5483
ENSG00000100412homo_sapiensENSP0000021625494.743686.6667leptobrachium_leishanenseENSLLEP0000003922094.501386.445
ENSG00000100412homo_sapiensENSP0000021625489.230878.7179scophthalmus_maximusENSSMAP0000001151287.547277.2327
ENSG00000100412homo_sapiensENSP0000021625489.230879.4872scophthalmus_maximusENSSMAP0000006060183.054973.9857
ENSG00000100412homo_sapiensENSP0000021625490.128280.1282oryzias_melastigmaENSOMEP0000002660990.012880.0256

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001889involved_in liver development1IEAHomo_sapiens(9606)Process
GO:0003994enables aconitate hydratase activity2EXP,IBAHomo_sapiens(9606)Function
GO:0005506enables iron ion binding1IDAHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion2HDA,IBAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1TASHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol1IBAHomo_sapiens(9606)Component
GO:0006091involved_in generation of precursor metabolites and energy1TASHomo_sapiens(9606)Process
GO:0006099involved_in tricarboxylic acid cycle4IBA,IDA,IEA,TASHomo_sapiens(9606)Process
GO:0006101acts_upstream_of_or_within citrate metabolic process1IDAHomo_sapiens(9606)Process
GO:0006102involved_in isocitrate metabolic process1IEAHomo_sapiens(9606)Process
GO:0035900involved_in response to isolation stress1IEAHomo_sapiens(9606)Process
GO:0047780enables citrate dehydratase activity1IEAHomo_sapiens(9606)Function
GO:0051538enables 3 iron, 4 sulfur cluster binding1IEAHomo_sapiens(9606)Function
GO:0051539enables 4 iron, 4 sulfur cluster binding1IBAHomo_sapiens(9606)Function

Expression