RBP Type
Canonical_RBPs
Diseases
SARS-COV-OC43 Flaviviruses RV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Stress granucle
BulkPerturb-seq
Ensembl ID ENSG00000100353 Gene ID
8664 Accession
3278
Symbol
EIF3D
Alias
EIF3S7;eIF3-p66;eIF3-zeta
Full Name
eukaryotic translation initiation factor 3 subunit D
Status
Confidence
Length
18312 bases
Strand
Minus strand
Position
22 : 36510855 - 36529166
RNA binding domain
eIF-3_zeta
Summary
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000216190
eIF-3_zeta
PF05091 1.8e-215
1
ENSP00000385812
eIF-3_zeta
PF05091 1.8e-215
1
ENSP00000390438
eIF-3_zeta
PF05091 4e-84
1
ENSP00000391061
eIF-3_zeta
PF05091 2.4e-35
1
ENSP00000403584
eIF-3_zeta
PF05091 5.2e-35
1
ENSP00000385212
eIF-3_zeta
PF05091 3.2e-28
1
ENSP00000487325
eIF-3_zeta
PF05091 1.9e-05
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
30091184 Unconventional RNA-binding proteins step into the virus-host battlefront.
Manuel Garcia-Moreno
2018-11-01
Wiley interdisciplinary reviews. RNA
36997088 eIF3d: A driver of noncanonical cap-dependent translation of specific mRNAs and a trigger of biological/pathological processes.
Shijie Ma
2023-05-01
The Journal of biological chemistry
27462815 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
S Amy Lee
2016-08-04
Nature
37325473 LeishIF3d is a non-canonical cap-binding protein in Leishmania .
Priyanka Bose
2023-01-01
Frontiers in molecular biosciences
22190034 Global landscape of HIV-human protein complexes.
Stefanie Jäger
2011-12-21
Nature
25539953 The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis.
M Antonio Rezende
2014-12-23
BMC genomics
26828225 Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation.
Nehal Thakor
2017-05-04
RNA biology
37144468 Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity.
Richard She
2023-07-07
Nucleic acids research
Name
Transcript ID
bp
Protein
Translation ID
EIF3D-201
ENST00000216190
1880
548aa
ENSP00000216190
EIF3D-211
ENST00000478547
452
49aa
ENSP00000487325
EIF3D-209
ENST00000462641
887
No protein
-
EIF3D-203
ENST00000405442
1851
548aa
ENSP00000385812
EIF3D-204
ENST00000426531
710
No protein
-
EIF3D-208
ENST00000458572
883
105aa
ENSP00000391061
EIF3D-210
ENST00000462794
764
No protein
-
EIF3D-206
ENST00000455547
996
269aa
ENSP00000390438
EIF3D-207
ENST00000457241
729
173aa
ENSP00000403584
EIF3D-205
ENST00000432675
678
No protein
-
EIF3D-202
ENST00000402116
581
123aa
ENSP00000385212
EIF3D-212
ENST00000496875
604
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
8350 Heart Rate 3.11348536831894E-6 17903306 53860 Potassium 9.3710000E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000100353
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000100353 homo_sapiens ENSP00000216190 100 100 nomascus_leucogenys ENSNLEP00000017822 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 pan_paniscus ENSPPAP00000016283 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 pongo_abelii ENSPPYP00000013136 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 pan_troglodytes ENSPTRP00000024650 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 gorilla_gorilla ENSGGOP00000016872 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 98.3577 95.6204 ornithorhynchus_anatinus ENSOANP00000011913 99.2634 96.5009 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 96.8978 sarcophilus_harrisii ENSSHAP00000013112 96.9534 95.1613 ENSG00000100353 homo_sapiens ENSP00000216190 98.5401 97.2628 notamacropus_eugenii ENSMEUP00000004163 99.2647 97.9779 ENSG00000100353 homo_sapiens ENSP00000216190 96.1679 95.438 choloepus_hoffmanni ENSCHOP00000004263 97.5926 96.8519 ENSG00000100353 homo_sapiens ENSP00000216190 54.1971 53.1022 dasypus_novemcinctus ENSDNOP00000014352 95.8064 93.871 ENSG00000100353 homo_sapiens ENSP00000216190 89.9635 89.4161 erinaceus_europaeus ENSEEUP00000014403 90.293 89.7436 ENSG00000100353 homo_sapiens ENSP00000216190 70.2555 65.6934 echinops_telfairi ENSETEP00000013233 88.1007 82.3799 ENSG00000100353 homo_sapiens ENSP00000216190 73.9051 69.708 echinops_telfairi ENSETEP00000007643 88.6214 83.5886 ENSG00000100353 homo_sapiens ENSP00000216190 80.292 78.4672 echinops_telfairi ENSETEP00000001677 85.9375 83.9844 ENSG00000100353 homo_sapiens ENSP00000216190 45.9854 43.4307 echinops_telfairi ENSETEP00000016436 85.4237 80.678 ENSG00000100353 homo_sapiens ENSP00000216190 100 99.8175 callithrix_jacchus ENSCJAP00000025625 99.8178 99.6357 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 cercocebus_atys ENSCATP00000045155 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 macaca_fascicularis ENSMFAP00000045511 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 macaca_mulatta ENSMMUP00000042822 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 macaca_nemestrina ENSMNEP00000002796 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 papio_anubis ENSPANP00000040832 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 mandrillus_leucophaeus ENSMLEP00000026103 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 98.5401 tursiops_truncatus ENSTTRP00000006284 99.4505 98.9011 ENSG00000100353 homo_sapiens ENSP00000216190 99.2701 98.5401 vulpes_vulpes ENSVVUP00000032529 96.6252 95.9147 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 mus_spretus MGP_SPRETEiJ_P0040622 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.0876 equus_asinus ENSEASP00005027786 99.635 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 capra_hircus ENSCHIP00000009152 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 96.5328 loxodonta_africana ENSLAFP00000001430 97.6277 96.5328 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 panthera_leo ENSPLOP00000004035 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.2701 ailuropoda_melanoleuca ENSAMEP00000010164 99.8175 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 bos_indicus_hybrid ENSBIXP00005042367 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.7226 oryctolagus_cuniculus ENSOCUP00000005507 98.2047 97.1275 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 98.5401 equus_caballus ENSECAP00000020144 99.635 98.5401 ENSG00000100353 homo_sapiens ENSP00000216190 99.2701 98.5401 canis_lupus_familiaris ENSCAFP00845011630 96.6252 95.9147 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 panthera_pardus ENSPPRP00000014300 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.2701 marmota_marmota_marmota ENSMMMP00000018585 99.8175 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 balaenoptera_musculus ENSBMSP00010012304 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 98.7226 cavia_porcellus ENSCPOP00000002302 93.8144 92.9553 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 98.7226 felis_catus ENSFCAP00000034937 98.5481 98.1851 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 98.3577 ursus_americanus ENSUAMP00000022232 99.4505 98.7179 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 97.4453 monodelphis_domestica ENSMODP00000000978 94.5993 93.0314 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 bison_bison_bison ENSBBBP00000025404 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 monodon_monoceros ENSMMNP00015023232 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 sus_scrofa ENSSSCP00000000145 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 microcebus_murinus ENSMICP00000036741 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 octodon_degus ENSODEP00000014944 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.7226 jaculus_jaculus ENSJJAP00000006122 99.8175 98.7226 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 ovis_aries_rambouillet ENSOARP00020028004 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 ursus_maritimus ENSUMAP00000021637 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 83.7591 83.2117 ochotona_princeps ENSOPRP00000006342 93.4827 92.8717 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 delphinapterus_leucas ENSDLEP00000008648 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 physeter_catodon ENSPCTP00005029760 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 mus_caroli MGP_CAROLIEiJ_P0038819 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 mus_musculus ENSMUSP00000098053 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.0876 dipodomys_ordii ENSDORP00000009861 99.635 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 57.4818 51.6423 mustela_putorius_furo ENSMPUP00000012487 70.3125 63.1696 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 aotus_nancymaae ENSANAP00000017970 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 saimiri_boliviensis_boliviensis ENSSBOP00000033381 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 49.635 48.5401 vicugna_pacos ENSVPAP00000000333 94.4444 92.3611 ENSG00000100353 homo_sapiens ENSP00000216190 99.2701 99.2701 chlorocebus_sabaeus ENSCSAP00000004155 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 92.1533 91.6058 tupaia_belangeri ENSTBEP00000005405 99.6055 99.0138 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 mesocricetus_auratus ENSMAUP00000013001 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 phocoena_sinus ENSPSNP00000008617 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.4526 98.9051 camelus_dromedarius ENSCDRP00005030149 99.4526 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 100 99.8175 carlito_syrichta ENSTSYP00000007835 100 99.8175 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 98.3577 panthera_tigris_altaica ENSPTIP00000012077 99.8155 99.4465 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 rattus_norvegicus ENSRNOP00000032361 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 64.5985 62.5912 prolemur_simus ENSPSMP00000035068 96.4578 93.4605 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 prolemur_simus ENSPSMP00000020770 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.7226 microtus_ochrogaster ENSMOCP00000011364 99.8175 98.7226 ENSG00000100353 homo_sapiens ENSP00000216190 78.6496 77.7372 sorex_araneus ENSSARP00000011283 88.501 87.4743 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 peromyscus_maniculatus_bairdii ENSPEMP00000014176 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 bos_mutus ENSBMUP00000033268 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 mus_spicilegus ENSMSIP00000024410 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 98.7226 cricetulus_griseus_chok1gshd ENSCGRP00001016174 99.635 98.7226 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.0876 pteropus_vampyrus ENSPVAP00000001903 99.8175 99.0876 ENSG00000100353 homo_sapiens ENSP00000216190 99.4526 98.9051 myotis_lucifugus ENSMLUP00000014448 99.4526 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 97.6277 vombatus_ursinus ENSVURP00010005682 99.0859 97.8062 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 rhinolophus_ferrumequinum ENSRFEP00010006002 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 98.1752 neovison_vison ENSNVIP00000004361 98.3666 97.6407 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 bos_taurus ENSBTAP00000037804 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 64.5985 60.9489 heterocephalus_glaber_female ENSHGLP00000000113 87.8412 82.8784 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 rhinopithecus_bieti ENSRBIP00000035894 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 99.2701 98.5401 canis_lupus_dingo ENSCAFP00020005467 96.6252 95.9147 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.2701 sciurus_vulgaris ENSSVLP00005021840 99.8175 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 97.8102 phascolarctos_cinereus ENSPCIP00000028912 99.0859 97.989 ENSG00000100353 homo_sapiens ENSP00000216190 85.5839 85.0365 procavia_capensis ENSPCAP00000007313 86.2132 85.6618 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.9051 nannospalax_galili ENSNGAP00000009305 99.8175 98.9051 ENSG00000100353 homo_sapiens ENSP00000216190 86.6788 83.9416 bos_grunniens ENSBGRP00000013369 93.8735 90.9091 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 98.7226 chinchilla_lanigera ENSCLAP00000024100 99.635 98.7226 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 cervus_hanglu_yarkandensis ENSCHYP00000017597 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.4526 catagonus_wagneri ENSCWAP00000013182 99.8175 99.4526 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.2701 ictidomys_tridecemlineatus ENSSTOP00000010167 99.8175 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 otolemur_garnettii ENSOGAP00000002668 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 cebus_imitator ENSCCAP00000019062 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 99.2701 urocitellus_parryii ENSUPAP00010006126 99.8175 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 99.635 99.2701 moschus_moschiferus ENSMMSP00000023205 99.635 99.2701 ENSG00000100353 homo_sapiens ENSP00000216190 100 100 rhinopithecus_roxellana ENSRROP00000031827 100 100 ENSG00000100353 homo_sapiens ENSP00000216190 99.8175 98.7226 mus_pahari MGP_PahariEiJ_P0042178 99.8175 98.7226 ENSG00000100353 homo_sapiens ENSP00000216190 95.2555 94.8905 propithecus_coquereli ENSPCOP00000006721 99.8088 99.4264 ENSG00000100353 homo_sapiens ENSP00000216190 63.5037 45.8029 caenorhabditis_elegans R08D7.3.1 61.0526 44.0351 ENSG00000100353 homo_sapiens ENSP00000216190 71.8978 54.3796 drosophila_melanogaster FBpp0082019 71.5064 54.0835 ENSG00000100353 homo_sapiens ENSP00000216190 73.7226 57.2993 drosophila_melanogaster FBpp0088565 72.1429 56.0714 ENSG00000100353 homo_sapiens ENSP00000216190 81.3869 65.6934 ciona_intestinalis ENSCINP00000007610 80.5054 64.9819 ENSG00000100353 homo_sapiens ENSP00000216190 48.5401 43.2482 petromyzon_marinus ENSPMAP00000008988 89.2617 79.5302 ENSG00000100353 homo_sapiens ENSP00000216190 80.292 69.708 eptatretus_burgeri ENSEBUP00000015031 88.3534 76.7068 ENSG00000100353 homo_sapiens ENSP00000216190 93.7956 84.1241 callorhinchus_milii ENSCMIP00000027178 92.2801 82.7648 ENSG00000100353 homo_sapiens ENSP00000216190 93.2482 86.8613 latimeria_chalumnae ENSLACP00000001800 94.2804 87.8229 ENSG00000100353 homo_sapiens ENSP00000216190 21.5328 20.073 lepisosteus_oculatus ENSLOCP00000014008 97.5207 90.9091 ENSG00000100353 homo_sapiens ENSP00000216190 93.6131 87.4088 clupea_harengus ENSCHAP00000007817 90.3169 84.331 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.0584 danio_rerio ENSDARP00000011011 96.7391 90.3986 ENSG00000100353 homo_sapiens ENSP00000216190 96.7153 89.9635 carassius_auratus ENSCARP00000135123 89.983 83.7012 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.0584 carassius_auratus ENSCARP00000080410 87.5205 81.9376 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 90.3285 astyanax_mexicanus ENSAMXP00000018062 96.7391 89.6739 ENSG00000100353 homo_sapiens ENSP00000216190 96.3504 89.9635 ictalurus_punctatus ENSIPUP00000025551 94.964 88.6691 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 91.0584 esox_lucius ENSELUP00000019334 96.1957 90.3986 ENSG00000100353 homo_sapiens ENSP00000216190 93.4307 87.0438 electrophorus_electricus ENSEEEP00000008935 90.1408 83.9789 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 90.8759 oncorhynchus_kisutch ENSOKIP00005004892 90.6463 84.6939 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.6934 oncorhynchus_kisutch ENSOKIP00005011304 90.6303 84.6678 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.5109 oncorhynchus_mykiss ENSOMYP00000021954 90.1695 84.0678 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 90.8759 oncorhynchus_mykiss ENSOMYP00000026996 90.6463 84.6939 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.8759 salmo_salar ENSSSAP00000175448 96.2025 90.0543 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.0584 salmo_salar ENSSSAP00000002017 96.036 89.9099 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 90.6934 salmo_trutta ENSSTUP00000042212 90.6463 84.5238 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 90.6934 salmo_trutta ENSSTUP00000009164 90.1861 84.0948 ENSG00000100353 homo_sapiens ENSP00000216190 91.7883 86.4964 gadus_morhua ENSGMOP00000038639 73.0044 68.7954 ENSG00000100353 homo_sapiens ENSP00000216190 10.219 9.48905 fundulus_heteroclitus ENSFHEP00000013490 96.5517 89.6552 ENSG00000100353 homo_sapiens ENSP00000216190 10.219 9.48905 poecilia_reticulata ENSPREP00000018816 96.5517 89.6552 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.6058 xiphophorus_maculatus ENSXMAP00000031584 89.1304 83.9465 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 90.5109 oryzias_latipes ENSORLP00000001790 94.484 88.2562 ENSG00000100353 homo_sapiens ENSP00000216190 95.8029 90.5109 cyclopterus_lumpus ENSCLMP00005012370 94.5946 89.3694 ENSG00000100353 homo_sapiens ENSP00000216190 97.8102 92.1533 oreochromis_niloticus ENSONIP00000012201 97.1014 91.4855 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 91.9708 haplochromis_burtoni ENSHBUP00000031448 96.9203 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 80.4744 73.1752 astatotilapia_calliptera ENSACLP00000032181 89.0909 81.0101 ENSG00000100353 homo_sapiens ENSP00000216190 80.4744 73.1752 astatotilapia_calliptera ENSACLP00000032311 89.0909 81.0101 ENSG00000100353 homo_sapiens ENSP00000216190 76.0949 70.438 astatotilapia_calliptera ENSACLP00000031682 92.4612 85.5876 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 91.7883 astatotilapia_calliptera ENSACLP00000031279 96.9035 91.6211 ENSG00000100353 homo_sapiens ENSP00000216190 80.1095 72.2628 astatotilapia_calliptera ENSACLP00000032068 84.749 76.4479 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.4234 sparus_aurata ENSSAUP00010068601 96.9091 91.0909 ENSG00000100353 homo_sapiens ENSP00000216190 95.073 89.4161 lates_calcarifer ENSLCAP00010031542 94.8998 89.2532 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 89.781 xenopus_tropicalis ENSXETP00000056971 96.1957 89.1304 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.6204 chrysemys_picta_bellii ENSCPBP00000022826 99.0859 95.7952 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 95.438 sphenodon_punctatus ENSSPUP00000015128 99.2687 95.6124 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 95.2555 crocodylus_porosus ENSCPRP00005027329 96.6071 93.2143 ENSG00000100353 homo_sapiens ENSP00000216190 97.9927 94.1606 laticauda_laticaudata ENSLLTP00000018280 93.554 89.8955 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 93.9781 notechis_scutatus ENSNSUP00000007096 96.0503 92.4596 ENSG00000100353 homo_sapiens ENSP00000216190 98.1752 94.708 pseudonaja_textilis ENSPTXP00000000852 98.3547 94.8812 ENSG00000100353 homo_sapiens ENSP00000216190 67.5182 65.146 anas_platyrhynchos_platyrhynchos ENSAPLP00000002086 93.4343 90.1515 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 95.6204 gallus_gallus ENSGALP00010020822 99.0876 95.6204 ENSG00000100353 homo_sapiens ENSP00000216190 81.3869 78.4672 meleagris_gallopavo ENSMGAP00000013331 98.8913 95.3437 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.438 serinus_canaria ENSSCAP00000005082 98.9051 95.438 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.438 parus_major ENSPMJP00000010206 98.9051 95.438 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 94.5256 anolis_carolinensis ENSACAP00000016055 98.9031 94.6984 ENSG00000100353 homo_sapiens ENSP00000216190 10.4015 9.85401 neolamprologus_brichardi ENSNBRP00000014625 93.4426 88.5246 ENSG00000100353 homo_sapiens ENSP00000216190 98.1752 94.708 naja_naja ENSNNAP00000011822 98.3547 94.8812 ENSG00000100353 homo_sapiens ENSP00000216190 98.3577 93.9781 podarcis_muralis ENSPMRP00000014777 86.24 82.4 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 95.2555 geospiza_fortis ENSGFOP00000012461 98.7226 95.2555 ENSG00000100353 homo_sapiens ENSP00000216190 97.8102 94.3431 taeniopygia_guttata ENSTGUP00000011054 97.2777 93.8294 ENSG00000100353 homo_sapiens ENSP00000216190 48.1752 44.3431 erpetoichthys_calabaricus ENSECRP00000021611 95.6522 88.0435 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.9708 kryptolebias_marmoratus ENSKMAP00000009538 96.558 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.2555 salvator_merianae ENSSMRP00000020237 99.0859 95.4296 ENSG00000100353 homo_sapiens ENSP00000216190 10.7664 9.12409 oryzias_javanicus ENSOJAP00000002002 88.0597 74.6269 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 92.1533 amphilophus_citrinellus ENSACIP00000017775 95.0178 89.8577 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.6058 dicentrarchus_labrax ENSDLAP00005083580 96.7391 90.942 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.7883 amphiprion_percula ENSAPEP00000028704 96.7391 91.1232 ENSG00000100353 homo_sapiens ENSP00000216190 60.219 57.1168 oryzias_sinensis ENSOSIP00000005210 97.3451 92.3304 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 90.5109 oryzias_sinensis ENSOSIP00000021873 95.8484 89.5307 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 95.8029 pelodiscus_sinensis ENSPSIP00000012174 99.2687 95.9781 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.9854 gopherus_evgoodei ENSGEVP00005027826 99.0859 96.1609 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.6204 chelonoidis_abingdonii ENSCABP00000024294 99.0859 95.7952 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.9708 seriola_dumerili ENSSDUP00000032332 96.558 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 96.5328 90.3285 cottoperca_gobio ENSCGOP00000001993 96.1818 90 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 95.8029 struthio_camelus_australis ENSSCUP00000022885 99.2687 95.9781 ENSG00000100353 homo_sapiens ENSP00000216190 98.5401 94.708 anser_brachyrhynchus ENSABRP00000003245 98.9011 95.0549 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.6934 gasterosteus_aculeatus ENSGACP00000019185 95.8559 89.5496 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.2409 cynoglossus_semilaevis ENSCSEP00000032016 96.3834 90.4159 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 91.9708 poecilia_formosa ENSPFOP00000007599 96.9203 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 92.5182 myripristis_murdjan ENSMMDP00005033684 97.0962 92.0145 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 91.2409 sander_lucioperca ENSSLUP00000018226 96.5455 90.9091 ENSG00000100353 homo_sapiens ENSP00000216190 99.0876 95.8029 strigops_habroptila ENSSHBP00005002622 99.0876 95.8029 ENSG00000100353 homo_sapiens ENSP00000216190 52.0073 48.7226 amphiprion_ocellaris ENSAOCP00000021275 93.4426 87.541 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.7883 amphiprion_ocellaris ENSAOCP00000017387 96.7391 91.1232 ENSG00000100353 homo_sapiens ENSP00000216190 98.9051 95.6204 terrapene_carolina_triunguis ENSTMTP00000021635 99.0859 95.7952 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 90.8759 hucho_hucho ENSHHUP00000046428 86.9494 81.2398 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 90.6934 hucho_hucho ENSHHUP00000017698 90.46 84.6678 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 91.2409 betta_splendens ENSBSLP00000018984 91.4089 85.9107 ENSG00000100353 homo_sapiens ENSP00000216190 97.8102 90.6934 pygocentrus_nattereri ENSPNAP00000022856 94.0351 87.193 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.9708 anabas_testudineus ENSATEP00000051893 96.7391 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 80.1095 63.6861 ciona_savignyi ENSCSAVP00000002456 77.9751 61.9893 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 91.7883 seriola_lalandi_dorsalis ENSSLDP00000008659 93.1579 88.2456 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.4234 labrus_bergylta ENSLBEP00000006889 96.9091 91.0909 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 91.7883 pundamilia_nyererei ENSPNYP00000015786 96.9203 91.1232 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.7883 mastacembelus_armatus ENSMAMP00000029974 96.558 91.1232 ENSG00000100353 homo_sapiens ENSP00000216190 97.4453 91.7883 stegastes_partitus ENSSPAP00000004654 96.7391 91.1232 ENSG00000100353 homo_sapiens ENSP00000216190 94.3431 87.9562 oncorhynchus_tshawytscha ENSOTSP00005065545 95.9184 89.4249 ENSG00000100353 homo_sapiens ENSP00000216190 94.3431 87.9562 oncorhynchus_tshawytscha ENSOTSP00005064308 95.9184 89.4249 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.6934 oncorhynchus_tshawytscha ENSOTSP00005074292 90.4762 84.5238 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 91.6058 acanthochromis_polyacanthus ENSAPOP00000000817 95 89.6429 ENSG00000100353 homo_sapiens ENSP00000216190 98.7226 95.438 aquila_chrysaetos_chrysaetos ENSACCP00020009276 93.2759 90.1724 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 91.9708 nothobranchius_furzeri ENSNFUP00015029299 96.9203 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 78.8321 74.4526 cyprinodon_variegatus ENSCVAP00000001048 85.2071 80.4734 ENSG00000100353 homo_sapiens ENSP00000216190 96.7153 90.6934 denticeps_clupeoides ENSDCDP00000019864 95.8409 89.8734 ENSG00000100353 homo_sapiens ENSP00000216190 97.2628 91.4234 larimichthys_crocea ENSLCRP00005040393 95.6912 89.9461 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 90.8759 takifugu_rubripes ENSTRUP00000086141 94.1489 88.2979 ENSG00000100353 homo_sapiens ENSP00000216190 98.5401 95.073 ficedula_albicollis ENSFALP00000030143 95.2381 91.8871 ENSG00000100353 homo_sapiens ENSP00000216190 96.7153 91.0584 hippocampus_comes ENSHCOP00000021181 96.3636 90.7273 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 90.8759 cyprinus_carpio_carpio ENSCCRP00000094455 96.3768 90.2174 ENSG00000100353 homo_sapiens ENSP00000216190 96.1679 89.5985 cyprinus_carpio_carpio ENSCCRP00000094444 92.4561 86.1404 ENSG00000100353 homo_sapiens ENSP00000216190 89.5985 85.7664 coturnix_japonica ENSCJPP00005016663 96.2745 92.1569 ENSG00000100353 homo_sapiens ENSP00000216190 93.4307 88.1387 poecilia_latipinna ENSPLAP00000026983 90.1408 85.0352 ENSG00000100353 homo_sapiens ENSP00000216190 48.3577 43.0657 sinocyclocheilus_grahami ENSSGRP00000004704 80.0604 71.2991 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 91.2409 sinocyclocheilus_grahami ENSSGRP00000026360 91.4089 85.9107 ENSG00000100353 homo_sapiens ENSP00000216190 13.6861 12.0438 sinocyclocheilus_grahami ENSSGRP00000024024 75.7576 66.6667 ENSG00000100353 homo_sapiens ENSP00000216190 92.8832 87.5912 maylandia_zebra ENSMZEP00005032225 94.6097 89.2193 ENSG00000100353 homo_sapiens ENSP00000216190 97.6277 91.9708 maylandia_zebra ENSMZEP00005031240 96.9203 91.3043 ENSG00000100353 homo_sapiens ENSP00000216190 95.9854 89.4161 tetraodon_nigroviridis ENSTNIP00000000100 95.1175 88.6076 ENSG00000100353 homo_sapiens ENSP00000216190 97.0803 91.4234 paramormyrops_kingsleyae ENSPKIP00000034674 93.4974 88.0492 ENSG00000100353 homo_sapiens ENSP00000216190 97.8102 92.1533 scleropages_formosus ENSSFOP00015037394 96.2298 90.6643 ENSG00000100353 homo_sapiens ENSP00000216190 96.5328 90.6934 leptobrachium_leishanense ENSLLEP00000043007 95.8333 90.0362 ENSG00000100353 homo_sapiens ENSP00000216190 96.8978 91.2409 scophthalmus_maximus ENSSMAP00000044287 94.484 88.968 ENSG00000100353 homo_sapiens ENSP00000216190 51.8248 46.3504 oryzias_melastigma ENSOMEP00000015715 94.0397 84.106 ENSG00000100353 homo_sapiens ENSP00000216190 50.365 46.1679 oryzias_melastigma ENSOMEP00000015740 92.3077 84.6154
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0001732 involved_in formation of cytoplasmic translation initiation complex 1 NAS Homo_sapiens(9606) Process GO:0002191 involved_in cap-dependent translational initiation 1 IDA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 2 HDA,IDA Homo_sapiens(9606) Function GO:0003743 contributes_to translation initiation factor activity 2 IC,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005829 located_in cytosol 1 TAS Homo_sapiens(9606) Component GO:0005852 part_of eukaryotic translation initiation factor 3 complex 3 IBA,IDA,IPI Homo_sapiens(9606) Component GO:0006413 involved_in translational initiation 3 IBA,IC,IDA Homo_sapiens(9606) Process GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0016282 part_of eukaryotic 43S preinitiation complex 1 IEA Homo_sapiens(9606) Component GO:0033290 part_of eukaryotic 48S preinitiation complex 1 IEA Homo_sapiens(9606) Component GO:0045202 located_in synapse 1 IEA Homo_sapiens(9606) Component GO:0045727 involved_in positive regulation of translation 1 IPI Homo_sapiens(9606) Process GO:0071541 part_of eukaryotic translation initiation factor 3 complex, eIF3m 1 IEA Homo_sapiens(9606) Component GO:0075522 involved_in IRES-dependent viral translational initiation 1 IDA Homo_sapiens(9606) Process GO:0075525 involved_in viral translational termination-reinitiation 1 IDA Homo_sapiens(9606) Process GO:0098808 enables mRNA cap binding 1 IDA Homo_sapiens(9606) Function GO:1902416 involved_in positive regulation of mRNA binding 1 IPI Homo_sapiens(9606) Process
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