Ensembl ID ENSG00000100353 Gene ID 8664 Accession 3278
Gene Symbol EIF3D Alias EIF3S7;eIF3-p66;eIF3-zeta Full Name eukaryotic translation initiation factor 3 subunit D
Position 22 : 36510855 - 36529166 Length 18312 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]

ENSG00000100353 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100353 EIF3D 0.33 3.63e-13 KIRC
ENSG00000100353 EIF3D -0.3 1.64e-12 BRCA
ENSG00000100353 EIF3D 0.66 1.51e-18 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100353 EIF3D colon cancer 25370813
ENSG00000100353 EIF3D non-small cell lung cancer 26008152
ENSG00000100353 EIF3D prostate cancer 26036682
ENSG00000100353 EIF3D tumor 27035563
ENSG00000100353 EIF3D cancer 27477275
ENSG00000100353 EIF3D cancers 28083147
ENSG00000100353 EIF3D ovarian cancer 28203520
ENSG00000100353 EIF3D gallbladder cancer 28594409
ENSG00000100353 EIF3D cancer 28801778
ENSG00000100353 EIF3D cancers 29050215
ENSG00000100353 EIF3D gastric cancer 29123423
ENSG00000100353 EIF3D colon cancer 30096129
ENSG00000100353 EIF3D tumour 31118081
ENSG00000100353 EIF3D cancer 31280863
ENSG00000100353 EIF3D tumor 31669222
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100353 EIF3D MESO 0.009 low
ENSG00000100353 EIF3D STAD 0.034 low
ENSG00000100353 EIF3D UVM 0.0028 low
ENSG00000100353 EIF3D PAAD 0.0052 high
ENSG00000100353 EIF3D UCEC 0.00026 low
ENSG00000100353 EIF3D THCA 0.038 low
ENSG00000100353 EIF3D ACC 7e-04 high
ENSG00000100353 EIF3D LUSC 0.016 low
ENSG00000100353 EIF3D HNSC 0.0021 high
ENSG00000100353 EIF3D KIRP 0.0051 high
ENSG00000100353 EIF3D KICH 0.042 high
ENSG00000100353 EIF3D LUAD 0.0023 high
ENSG00000100353 EIF3D PCPG 0.021 low
ENSG00000100353 EIF3D THYM 0.026 low
ENSG00000100353 EIF3D BRCA 0.036 low
ENSG00000100353 EIF3D ESCA 0.0058 low
ENSG00000100353 EIF3D KIRC 0.0083 low
ENSG00000100353 EIF3D PRAD 0.021 high
ENSG00000100353 EIF3D GBM 0.005 low
ENSG00000100353 EIF3D LIHC 0.00017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100353 EIF3D THYM Del 0.970980 0.043130 0.436505 0.130081