Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000099821 Gene ID 5442 Accession 9200
Symbol POLRMT Alias APOLMT;MTRNAP;MTRPOL;COXPD55;h-mtRPOL Full Name RNA polymerase mitochondrial
Status Confidence Length 16317 bases Strand Minus strand
Position 19 : 617221 - 633537 RNA binding domain RNA_pol , RPOL_N
Summary This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000465759 RNA_pol PF00940 2.7e-159 1
ENSP00000465759 RPOL_N PF14700 1.3e-53 2
ENSP00000468658 RNA_pol PF00940 5.8e-41 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34071708 Engineering Genetic Systems for Treating Mitochondrial Diseases. Yoon-Ha Jang 2021-05-28 Pharmaceutics
26586915 Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import. Jessica Nouws 2016-01-08 The Journal of biological chemistry
37182101 MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells. Xingzhao Ji 2023-05-19 iScience
29880722 Mitochondrial DNA replication in mammalian cells: overview of the pathway. Maria Falkenberg 2018-07-20 Essays in biochemistry
35278431 Phosphorylation and acetylation of mitochondrial transcription factor A promote transcription processivity without compromising initiation or DNA compaction. D Sean Reardon 2022-04-01 The Journal of biological chemistry
25612828 Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation. Rui-Feng Yang 2015-01-23 Scientific reports
27726420 Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function. Hai-Bo Li 2016-11-01 DNA and cell biology
36838782 Structural and Molecular Basis for Mitochondrial DNA Replication and Transcription in Health and Antiviral Drug Toxicity. Joon Park 2023-02-14 Molecules (Basel, Switzerland)
31195723 Organization of DNA in Mammalian Mitochondria. Géraldine Farge 2019-06-05 International journal of molecular sciences
34779571 Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen. Mara Mennuni 2022-01-05 EMBO reports
21742773 p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB. F Renée Johnson 2011-08-15 Cancer research
37371693 Targeting Mitochondrial DNA Transcription by POLRMT Inhibition or Depletion as a Potential Strategy for Cancer Treatment. D C Sabrina Daglish 2023-05-31 Biomedicines
29180528 Simple In Vitro Assay To Evaluate the Incorporation Efficiency of Ribonucleotide Analog 5'-Triphosphates into RNA by Human Mitochondrial DNA-Dependent RNA Polymerase. Gaofei Lu 2018-02-01 Antimicrobial agents and chemotherapy
33259199 Application of Molecular Dynamics Simulations to the Design of Nucleotide Inhibitors Binding to Norovirus Polymerase. Holly Freedman 2020-12-28 Journal of chemical information and modeling
26590214 Mitochondrial Involvement in Vertebrate Speciation? The Case of Mito-nuclear Genetic Divergence in Chameleons. Dan Bar-Yaacov 2015-11-19 Genome biology and evolution

Transcripts

Name Transcript ID bp Protein Translation ID
POLRMT-202 ENST00000588649 3771 1230aa ENSP00000465759
POLRMT-207 ENST00000592633 469 No protein -
POLRMT-201 ENST00000587057 1229 No protein -
POLRMT-204 ENST00000590336 380 127aa ENSP00000468658
POLRMT-203 ENST00000589961 490 No protein -
POLRMT-206 ENST00000590709 1106 No protein -
POLRMT-205 ENST00000590573 1043 347aa ENSP00000466504
POLRMT-208 ENST00000592863 966 56aa ENSP00000473524

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
42467Platelet Function Tests1.9769800E-005-
59723Blood Pressure1.8383163E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000099821

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000099821homo_sapiensENSP0000046575996.016393.8211nomascus_leucogenysENSNLEP0000000093496.016393.8211
ENSG00000099821homo_sapiensENSP0000046575997.886297.4797pan_paniscusENSPPAP0000001547298.125597.718
ENSG00000099821homo_sapiensENSP0000046575996.585494.7154pongo_abeliiENSPPYP0000004176896.585494.7154
ENSG00000099821homo_sapiensENSP0000046575997.723697.561pan_troglodytesENSPTRP0000001725793.906293.75
ENSG00000099821homo_sapiensENSP0000046575978.536677.3171gorilla_gorillaENSGGOP0000002702794.985393.5103
ENSG00000099821homo_sapiensENSP0000046575968.780553.0894ornithorhynchus_anatinusENSOANP0000004085465.177250.3082
ENSG00000099821homo_sapiensENSP0000046575966.829350.7317sarcophilus_harrisiiENSSHAP0000003863666.077250.1608
ENSG00000099821homo_sapiensENSP0000046575938.37431.7886notamacropus_eugeniiENSMEUP0000001019339.864933.0236
ENSG00000099821homo_sapiensENSP0000046575975.121964.8781echinops_telfairiENSETEP0000000285275.675765.3563
ENSG00000099821homo_sapiensENSP0000046575983.333374.7154callithrix_jacchusENSCJAP0000002371784.362175.6379
ENSG00000099821homo_sapiensENSP0000046575991.300887.4797cercocebus_atysENSCATP0000003500891.449587.6221
ENSG00000099821homo_sapiensENSP0000046575980.081375.6911macaca_fascicularisENSMFAP0000001660586.479481.7384
ENSG00000099821homo_sapiensENSP0000046575991.62687.7236macaca_mulattaENSMMUP0000006398491.775287.8664
ENSG00000099821homo_sapiensENSP0000046575990.569186.5041macaca_nemestrinaENSMNEP0000003141389.048885.052
ENSG00000099821homo_sapiensENSP0000046575961.056956.8293papio_anubisENSPANP0000000125485.535379.6128
ENSG00000099821homo_sapiensENSP0000046575979.512275.7724mandrillus_leucophaeusENSMLEP0000002641791.061586.7784
ENSG00000099821homo_sapiensENSP0000046575958.699251.5447tursiops_truncatusENSTTRP0000001075058.938851.7551
ENSG00000099821homo_sapiensENSP0000046575973.739864.4715vulpes_vulpesENSVVUP0000003105273.920164.6292
ENSG00000099821homo_sapiensENSP0000046575977.235865.7724mus_spretusMGP_SPRETEiJ_P002488378.707567.0257
ENSG00000099821homo_sapiensENSP0000046575982.43972.6829equus_asinusENSEASP0000503157282.640672.8606
ENSG00000099821homo_sapiensENSP0000046575978.780567.8049capra_hircusENSCHIP0000001097880.016568.8687
ENSG00000099821homo_sapiensENSP0000046575979.024468.8618loxodonta_africanaENSLAFP000000015578069.7119
ENSG00000099821homo_sapiensENSP0000046575974.390264.8781panthera_leoENSPLOP0000000756575.432865.7873
ENSG00000099821homo_sapiensENSP0000046575981.382170.813ailuropoda_melanoleucaENSAMEP0000000292477.838367.7294
ENSG00000099821homo_sapiensENSP0000046575979.918768.374bos_indicus_hybridENSBIXP0000502583480.441968.8216
ENSG00000099821homo_sapiensENSP0000046575980.325270.0813equus_caballusENSECAP0000005267575.766966.1043
ENSG00000099821homo_sapiensENSP0000046575980.162669.9187canis_lupus_familiarisENSCAFP0084502109377.212267.3453
ENSG00000099821homo_sapiensENSP0000046575973.658564.8781panthera_pardusENSPPRP0000000595579.265169.8163
ENSG00000099821homo_sapiensENSP0000046575973.739865.4472marmota_marmota_marmotaENSMMMP0000001265579.631370.676
ENSG00000099821homo_sapiensENSP0000046575981.056970.7317balaenoptera_musculusENSBMSP0001000106581.122970.7893
ENSG00000099821homo_sapiensENSP0000046575972.520360.9756cavia_porcellusENSCPOP0000001558675.465363.4518
ENSG00000099821homo_sapiensENSP0000046575982.113871.5447felis_catusENSFCAP0000005748672.349663.0373
ENSG00000099821homo_sapiensENSP0000046575980.81370.5691ursus_americanusENSUAMP0000002516781.010670.7416
ENSG00000099821homo_sapiensENSP0000046575965.121949.7561monodelphis_domesticaENSMODP0000000803965.980250.4119
ENSG00000099821homo_sapiensENSP0000046575969.674858.6992bison_bison_bisonENSBBBP0000000886577.137764.9865
ENSG00000099821homo_sapiensENSP0000046575981.463470.7317monodon_monocerosENSMMNP0001500100481.529770.7893
ENSG00000099821homo_sapiensENSP0000046575981.056970.3252sus_scrofaENSSSCP0000003751681.788470.9598
ENSG00000099821homo_sapiensENSP0000046575982.764273.4959microcebus_murinusENSMICP0000001523882.495973.2577
ENSG00000099821homo_sapiensENSP0000046575975.121964.7967jaculus_jaculusENSJJAP0000000888579.109668.2363
ENSG00000099821homo_sapiensENSP0000046575958.292752.6829ochotona_princepsENSOPRP0000001240361.229755.3373
ENSG00000099821homo_sapiensENSP0000046575981.463470.7317delphinapterus_leucasENSDLEP0000001185281.529770.7893
ENSG00000099821homo_sapiensENSP0000046575973.495962.8455physeter_catodonENSPCTP0000502981868.8558.8728
ENSG00000099821homo_sapiensENSP0000046575977.073265.4472mus_caroliMGP_CAROLIEiJ_P002373478.541866.6943
ENSG00000099821homo_sapiensENSP0000046575977.317165.8537mus_musculusENSMUSP0000002058078.790467.1085
ENSG00000099821homo_sapiensENSP0000046575976.585464.6341dipodomys_ordiiENSDORP0000001328179.159766.8067
ENSG00000099821homo_sapiensENSP0000046575979.593568.9431mustela_putorius_furoENSMPUP0000000983579.528868.8871
ENSG00000099821homo_sapiensENSP0000046575985.447277.561aotus_nancymaaeENSANAP0000003031685.377777.498
ENSG00000099821homo_sapiensENSP0000046575984.06575.3659saimiri_boliviensis_boliviensisENSSBOP0000001746481.868673.3967
ENSG00000099821homo_sapiensENSP0000046575990.325286.1789chlorocebus_sabaeusENSCSAP0000000903990.398786.249
ENSG00000099821homo_sapiensENSP0000046575938.861834.7967tupaia_belangeriENSTBEP0000000157675.394367.5079
ENSG00000099821homo_sapiensENSP0000046575976.016364.2276mesocricetus_auratusENSMAUP0000002177778.046765.9432
ENSG00000099821homo_sapiensENSP0000046575981.382170.6504phocoena_sinusENSPSNP0000000991781.714370.9388
ENSG00000099821homo_sapiensENSP0000046575974.390265.3659camelus_dromedariusENSCDRP0000502745282.805472.7602
ENSG00000099821homo_sapiensENSP0000046575976.666764.2276rattus_norvegicusENSRNOP0000003244878.257365.5602
ENSG00000099821homo_sapiensENSP0000046575983.008173.7398prolemur_simusENSPSMP0000003334783.27973.9804
ENSG00000099821homo_sapiensENSP0000046575975.203362.6829microtus_ochrogasterENSMOCP0000000883276.955164.1431
ENSG00000099821homo_sapiensENSP0000046575976.991964.4715peromyscus_maniculatus_bairdiiENSPEMP0000001087778.654565.8638
ENSG00000099821homo_sapiensENSP0000046575975.93564.7967bos_mutusENSBMUP0000000414879.421867.7721
ENSG00000099821homo_sapiensENSP0000046575977.317165.7724mus_spicilegusENSMSIP0000000146278.790467.0257
ENSG00000099821homo_sapiensENSP0000046575977.235864.8781cricetulus_griseus_chok1gshdENSCGRP0000102293879.034966.3894
ENSG00000099821homo_sapiensENSP0000046575979.593569.4309pteropus_vampyrusENSPVAP0000000793680.70970.404
ENSG00000099821homo_sapiensENSP0000046575980.81368.4553myotis_lucifugusENSMLUP0000000841581.542269.073
ENSG00000099821homo_sapiensENSP0000046575966.910652.6829vombatus_ursinusENSVURP0001000051665.525551.5924
ENSG00000099821homo_sapiensENSP0000046575980.162669.3496rhinolophus_ferrumequinumENSRFEP0001002686180.753569.8608
ENSG00000099821homo_sapiensENSP0000046575979.837469.0244neovison_visonENSNVIP0000000264379.772568.9683
ENSG00000099821homo_sapiensENSP0000046575979.674868.2927bos_taurusENSBTAP0000002003480.065468.6274
ENSG00000099821homo_sapiensENSP0000046575975.447263.9837heterocephalus_glaber_femaleENSHGLP0000002711768.94558.4695
ENSG00000099821homo_sapiensENSP0000046575992.43988.374rhinopithecus_bietiENSRBIP0000000131092.892288.8072
ENSG00000099821homo_sapiensENSP0000046575980.081369.9187canis_lupus_dingoENSCAFP0002002130680.671670.4341
ENSG00000099821homo_sapiensENSP0000046575958.699250.9756sciurus_vulgarisENSSVLP0000503099879.515469.0529
ENSG00000099821homo_sapiensENSP0000046575959.349645.5285phascolarctos_cinereusENSPCIP0000000718866.183150.7706
ENSG00000099821homo_sapiensENSP0000046575973.089462.5203procavia_capensisENSPCAP0000001019673.688563.0328
ENSG00000099821homo_sapiensENSP0000046575977.886265.935nannospalax_galiliENSNGAP0000000428579.436167.2471
ENSG00000099821homo_sapiensENSP0000046575979.756168.2927bos_grunniensENSBGRP0000000902280.34468.7961
ENSG00000099821homo_sapiensENSP0000046575975.040663.5772chinchilla_lanigeraENSCLAP0000001082664.23154.4189
ENSG00000099821homo_sapiensENSP0000046575978.37466.9919cervus_hanglu_yarkandensisENSCHYP0000001058578.951767.4857
ENSG00000099821homo_sapiensENSP0000046575980.325268.5366catagonus_wagneriENSCWAP0000000276081.0569.155
ENSG00000099821homo_sapiensENSP0000046575979.837470.813ictidomys_tridecemlineatusENSSTOP0000000308382.313573.0092
ENSG00000099821homo_sapiensENSP0000046575983.414673.9024otolemur_garnettiiENSOGAP0000000708583.144273.6629
ENSG00000099821homo_sapiensENSP0000046575985.121977.0732cebus_imitatorENSCCAP0000001441082.832375
ENSG00000099821homo_sapiensENSP0000046575981.056972.0325urocitellus_parryiiENSUPAP0001001895981.788472.6825
ENSG00000099821homo_sapiensENSP0000046575979.024467.561moschus_moschiferusENSMMSP000000270858068.3951
ENSG00000099821homo_sapiensENSP0000046575991.869987.561rhinopithecus_roxellanaENSRROP0000003452390.472486.229
ENSG00000099821homo_sapiensENSP0000046575977.317165.1219mus_pahariMGP_PahariEiJ_P008688578.725266.3079
ENSG00000099821homo_sapiensENSP0000046575979.674870.9756propithecus_coquereliENSPCOP0000000670680.525971.7338
ENSG00000099821homo_sapiensENSP0000046575942.682925.7724caenorhabditis_elegansY105E8A.23b.145.415227.4221
ENSG00000099821homo_sapiensENSP0000046575955.12237.6423drosophila_melanogasterFBpp030456249.525233.8203
ENSG00000099821homo_sapiensENSP000004657598.536595.28455ciona_intestinalisENSCINP0000003653544.680927.6596
ENSG00000099821homo_sapiensENSP0000046575912.27649.34959ciona_intestinalisENSCINP0000000435663.983148.7288
ENSG00000099821homo_sapiensENSP0000046575946.666734.9594petromyzon_marinusENSPMAP0000000558265.450449.0308
ENSG00000099821homo_sapiensENSP0000046575948.536636.5041eptatretus_burgeriENSEBUP0000002181664.124648.2277
ENSG00000099821homo_sapiensENSP0000046575962.357744.5528callorhinchus_miliiENSCMIP0000001422962.868944.918
ENSG00000099821homo_sapiensENSP0000046575963.495945.3659latimeria_chalumnaeENSLACP0000001307564.22745.8882
ENSG00000099821homo_sapiensENSP0000046575956.74840.8943lepisosteus_oculatusENSLOCP0000000629355.617540.0797
ENSG00000099821homo_sapiensENSP0000046575963.495945.2846clupea_harengusENSCHAP0000004728260.636643.2453
ENSG00000099821homo_sapiensENSP0000046575962.682945.3659danio_rerioENSDARP0000013521360.187443.5597
ENSG00000099821homo_sapiensENSP0000046575963.25244.9594carassius_auratusENSCARP0000009017958.984141.9257
ENSG00000099821homo_sapiensENSP0000046575961.869943.9837carassius_auratusENSCARP0000001528457.132140.6156
ENSG00000099821homo_sapiensENSP0000046575963.089444.7967carassius_auratusENSCARP0000007430958.877141.8058
ENSG00000099821homo_sapiensENSP0000046575959.918742.3577carassius_auratusENSCARP0000005426855.247439.0555
ENSG00000099821homo_sapiensENSP0000046575963.008144.9594astyanax_mexicanusENSAMXP0000001881560.358343.0685
ENSG00000099821homo_sapiensENSP0000046575963.414646.9919ictalurus_punctatusENSIPUP0000000115659.907844.3932
ENSG00000099821homo_sapiensENSP0000046575961.707345.2033esox_luciusENSELUP0000002005556.557441.4307
ENSG00000099821homo_sapiensENSP0000046575961.219544.878electrophorus_electricusENSEEEP0000004776558.690643.0242
ENSG00000099821homo_sapiensENSP0000046575962.032545.6098oncorhynchus_kisutchENSOKIP0000502325557.282342.1171
ENSG00000099821homo_sapiensENSP0000046575962.682946.1789oncorhynchus_kisutchENSOKIP0000500893157.580342.4197
ENSG00000099821homo_sapiensENSP0000046575962.682946.1789oncorhynchus_mykissENSOMYP0000013729755.587640.9517
ENSG00000099821homo_sapiensENSP0000046575962.032545.6098oncorhynchus_mykissENSOMYP0000003556157.239342.0855
ENSG00000099821homo_sapiensENSP0000046575961.951244.9594salmo_salarENSSSAP0000003000454.196339.3314
ENSG00000099821homo_sapiensENSP0000046575961.951245.2033salmo_salarENSSSAP0000002949456.029440.8824
ENSG00000099821homo_sapiensENSP0000046575961.869945.3659salmo_truttaENSSTUP0000002243956.79141.6418
ENSG00000099821homo_sapiensENSP0000046575961.951245.122salmo_truttaENSSTUP0000010106856.277740.9897
ENSG00000099821homo_sapiensENSP0000046575962.43945.7724gadus_morhuaENSGMOP0000004225757.528142.1723
ENSG00000099821homo_sapiensENSP0000046575963.008144.3902fundulus_heteroclitusENSFHEP0000003385658.314541.0835
ENSG00000099821homo_sapiensENSP0000046575963.008144.5528poecilia_reticulataENSPREP0000001126958.623341.4523
ENSG00000099821homo_sapiensENSP0000046575963.008144.9594xiphophorus_maculatusENSXMAP0000001249058.667741.8622
ENSG00000099821homo_sapiensENSP0000046575962.682945.4472oryzias_latipesENSORLP0000000542457.195841.4688
ENSG00000099821homo_sapiensENSP0000046575961.869945.2846cyclopterus_lumpusENSCLMP0000500062657.175141.8482
ENSG00000099821homo_sapiensENSP0000046575963.577245.3659oreochromis_niloticusENSONIP0000004988058.79741.9549
ENSG00000099821homo_sapiensENSP0000046575963.658545.2846haplochromis_burtoniENSHBUP0000002703558.739741.7854
ENSG00000099821homo_sapiensENSP0000046575963.658545.3659astatotilapia_callipteraENSACLP0000000558958.739741.8605
ENSG00000099821homo_sapiensENSP0000046575962.520344.878sparus_aurataENSSAUP0001001278158.747142.1696
ENSG00000099821homo_sapiensENSP0000046575958.861842.439lates_calcariferENSLCAP0001000610958.059341.8605
ENSG00000099821homo_sapiensENSP0000046575962.520346.2602xenopus_tropicalisENSXETP0000001432862.317746.1102
ENSG00000099821homo_sapiensENSP0000046575963.414647.7236chrysemys_picta_belliiENSCPBP0000001316068.062851.2216
ENSG00000099821homo_sapiensENSP0000046575914.55289.02439sphenodon_punctatusENSSPUP0000001195336.983522.9339
ENSG00000099821homo_sapiensENSP0000046575917.073213.6585sphenodon_punctatusENSSPUP0000001198673.943759.1549
ENSG00000099821homo_sapiensENSP0000046575952.926839.5935crocodylus_porosusENSCPRP0000502158666.906550.0514
ENSG00000099821homo_sapiensENSP0000046575944.87833.9837pseudonaja_textilisENSPTXP0000000034070.408253.3163
ENSG00000099821homo_sapiensENSP0000046575964.06547.6423anas_platyrhynchos_platyrhynchosENSAPLP0000000253662.738946.6561
ENSG00000099821homo_sapiensENSP0000046575965.691146.8293gallus_gallusENSGALP0001004080165.372246.6019
ENSG00000099821homo_sapiensENSP0000046575962.520344.5528meleagris_gallopavoENSMGAP0000000298168.053148.4956
ENSG00000099821homo_sapiensENSP0000046575963.414646.9919serinus_canariaENSSCAP0000000754864.62347.8873
ENSG00000099821homo_sapiensENSP0000046575964.146348.2114parus_majorENSPMJP0000001453462.968947.3264
ENSG00000099821homo_sapiensENSP0000046575910.08137.96748anolis_carolinensisENSACAP0000000044263.917550.5155
ENSG00000099821homo_sapiensENSP0000046575962.926844.878neolamprologus_brichardiENSNBRP0000003095158.59241.7865
ENSG00000099821homo_sapiensENSP0000046575961.463443.5772naja_najaENSNNAP0000000068761.513443.6127
ENSG00000099821homo_sapiensENSP0000046575965.691149.2683podarcis_muralisENSPMRP0000003071464.536748.4026
ENSG00000099821homo_sapiensENSP0000046575964.06547.8862geospiza_fortisENSGFOP0000000908164.590248.2787
ENSG00000099821homo_sapiensENSP0000046575963.495947.3171taeniopygia_guttataENSTGUP0000002929058.196743.3681
ENSG00000099821homo_sapiensENSP0000046575962.845544.9594erpetoichthys_calabaricusENSECRP0000002037161.741244.1693
ENSG00000099821homo_sapiensENSP0000046575962.43944.1463kryptolebias_marmoratusENSKMAP0000000582560.14142.5215
ENSG00000099821homo_sapiensENSP0000046575961.62646.4228salvator_merianaeENSSMRP0000002099164.237348.3898
ENSG00000099821homo_sapiensENSP0000046575963.25246.3415oryzias_javanicusENSOJAP0000001975960.077244.0154
ENSG00000099821homo_sapiensENSP0000046575959.756143.252amphilophus_citrinellusENSACIP0000002073564.530346.7076
ENSG00000099821homo_sapiensENSP000004657596042.6016dicentrarchus_labraxENSDLAP0000506592959.564242.2922
ENSG00000099821homo_sapiensENSP0000046575963.658546.2602amphiprion_perculaENSAPEP0000001113758.872242.782
ENSG00000099821homo_sapiensENSP0000046575959.024440.7317oryzias_sinensisENSOSIP0000005161551.857135.7857
ENSG00000099821homo_sapiensENSP0000046575962.520346.9106gopherus_evgoodeiENSGEVP0000500600765.670449.2741
ENSG00000099821homo_sapiensENSP0000046575962.113847.2358chelonoidis_abingdoniiENSCABP0000000445466.900250.8757
ENSG00000099821homo_sapiensENSP0000046575962.764245.0406seriola_dumeriliENSSDUP0000000603657.741241.4361
ENSG00000099821homo_sapiensENSP0000046575961.788644.2276cottoperca_gobioENSCGOP0000000555856.505640.4461
ENSG00000099821homo_sapiensENSP0000046575962.195146.1789struthio_camelus_australisENSSCUP0000001653368.671550.9874
ENSG00000099821homo_sapiensENSP0000046575963.414648.1301anser_brachyrhynchusENSABRP0000000521662.903247.7419
ENSG00000099821homo_sapiensENSP0000046575960.162643.9024gasterosteus_aculeatusENSGACP0000001713362.978745.9574
ENSG00000099821homo_sapiensENSP0000046575962.113845.2846cynoglossus_semilaevisENSCSEP0000000419458.814542.8791
ENSG00000099821homo_sapiensENSP0000046575944.390228.6992poecilia_formosaENSPFOP0000002415652.958334.2386
ENSG00000099821homo_sapiensENSP0000046575962.926845.5285myripristis_murdjanENSMMDP0000500601757.847541.8535
ENSG00000099821homo_sapiensENSP0000046575962.926845.3659sander_luciopercaENSSLUP0000003235857.847541.704
ENSG00000099821homo_sapiensENSP0000046575963.333346.8293strigops_habroptilaENSSHBP0000500838763.957347.2906
ENSG00000099821homo_sapiensENSP0000046575963.495946.0976amphiprion_ocellarisENSAOCP0000002969858.721842.6316
ENSG00000099821homo_sapiensENSP0000046575963.577247.3984terrapene_carolina_triunguisENSTMTP0000001183467.823150.5637
ENSG00000099821homo_sapiensENSP0000046575962.682945.8537hucho_huchoENSHHUP0000004684457.666442.184
ENSG00000099821homo_sapiensENSP0000046575961.463445.122hucho_huchoENSHHUP0000006566354.822340.2466
ENSG00000099821homo_sapiensENSP0000046575961.951244.2276betta_splendensENSBSLP0000000352557.466141.0256
ENSG00000099821homo_sapiensENSP0000046575962.764245.8537pygocentrus_nattereriENSPNAP0000001383958.132542.4699
ENSG00000099821homo_sapiensENSP0000046575962.195144.7967anabas_testudineusENSATEP0000003495957.692341.5535
ENSG00000099821homo_sapiensENSP0000046575938.211428.1301ciona_savignyiENSCSAVP0000000078059.720543.9644
ENSG00000099821homo_sapiensENSP0000046575942.682926.1789saccharomyces_cerevisiaeYFL036W38.860123.8342
ENSG00000099821homo_sapiensENSP0000046575963.008144.7967seriola_lalandi_dorsalisENSSLDP0000001339357.965641.2117
ENSG00000099821homo_sapiensENSP0000046575963.25245.6098labrus_bergyltaENSLBEP0000002150158.277242.0225
ENSG00000099821homo_sapiensENSP0000046575963.414645.122pundamilia_nyerereiENSPNYP0000002760158.514641.6354
ENSG00000099821homo_sapiensENSP0000046575962.601644.9594mastacembelus_armatusENSMAMP0000002870358.069441.7044
ENSG00000099821homo_sapiensENSP0000046575962.926845.6911stegastes_partitusENSSPAP0000002484457.718141.909
ENSG00000099821homo_sapiensENSP0000046575961.951245.5285oncorhynchus_tshawytschaENSOTSP0000500029056.865741.791
ENSG00000099821homo_sapiensENSP0000046575962.845546.3415oncorhynchus_tshawytschaENSOTSP0000505772155.731841.0959
ENSG00000099821homo_sapiensENSP0000046575963.577245.6911acanthochromis_polyacanthusENSAPOP0000000254358.79742.2556
ENSG00000099821homo_sapiensENSP0000046575962.032545.7724aquila_chrysaetos_chrysaetosENSACCP0002000467465.269548.1608
ENSG00000099821homo_sapiensENSP0000046575962.520344.6341nothobranchius_furzeriENSNFUP0001505022456.96340.6667
ENSG00000099821homo_sapiensENSP0000046575963.414644.4715cyprinodon_variegatusENSCVAP0000000458658.956941.3454
ENSG00000099821homo_sapiensENSP0000046575962.357745.122denticeps_clupeoidesENSDCDP0000002677459.781843.258
ENSG00000099821homo_sapiensENSP0000046575962.195144.6341larimichthys_croceaENSLCRP0000503554455.798740.0438
ENSG00000099821homo_sapiensENSP0000046575961.707344.3089takifugu_rubripesENSTRUP0000006182556.768940.7629
ENSG00000099821homo_sapiensENSP0000046575963.821147.7236ficedula_albicollisENSFALP0000002817864.609148.3128
ENSG00000099821homo_sapiensENSP0000046575960.569144.2276hippocampus_comesENSHCOP0000000068961.065644.5902
ENSG00000099821homo_sapiensENSP0000046575962.845544.5528cyprinus_carpio_carpioENSCCRP0000013412658.03341.1411
ENSG00000099821homo_sapiensENSP0000046575962.764244.4715cyprinus_carpio_carpioENSCCRP0000012750557.827740.9738
ENSG00000099821homo_sapiensENSP0000046575963.008145.4472coturnix_japonicaENSCJPP0000501214967.041548.3564
ENSG00000099821homo_sapiensENSP0000046575953.495936.5854poecilia_latipinnaENSPLAP0000002173457.068539.0286
ENSG00000099821homo_sapiensENSP0000046575951.544737.3171sinocyclocheilus_grahamiENSSGRP0000002234358.272142.1875
ENSG00000099821homo_sapiensENSP0000046575963.089444.9594sinocyclocheilus_grahamiENSSGRP0000005132757.867341.2379
ENSG00000099821homo_sapiensENSP0000046575963.658545.3659maylandia_zebraENSMZEP0000501321758.739741.8605
ENSG00000099821homo_sapiensENSP0000046575955.528541.5447tetraodon_nigroviridisENSTNIP0000001355767.35750.3945
ENSG00000099821homo_sapiensENSP0000046575962.764246.0163paramormyrops_kingsleyaeENSPKIP0000000948260.265444.1842
ENSG00000099821homo_sapiensENSP0000046575963.414646.0163scleropages_formosusENSSFOP0001500771360.985144.2533
ENSG00000099821homo_sapiensENSP0000046575961.219543.9024leptobrachium_leishanenseENSLLEP0000000071860.433443.3387
ENSG00000099821homo_sapiensENSP0000046575961.788644.2276scophthalmus_maximusENSSMAP0000001931154.363438.9127
ENSG00000099821homo_sapiensENSP0000046575963.414646.0163oryzias_melastigmaENSOMEP0000000720560.046243.572

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0001018enables mitochondrial promoter sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003896enables DNA primase activity1IDAHomo_sapiens(9606)Function
GO:0003899enables DNA-directed 5-3 RNA polymerase activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix3IDA,NAS,TASHomo_sapiens(9606)Component
GO:0006269involved_in DNA replication, synthesis of RNA primer1IEAHomo_sapiens(9606)Process
GO:0006390involved_in mitochondrial transcription3IBA,IDA,TASHomo_sapiens(9606)Process
GO:0006391involved_in transcription initiation at mitochondrial promoter1IDAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0034245part_of mitochondrial DNA-directed RNA polymerase complex1IBAHomo_sapiens(9606)Component
GO:0042645located_in mitochondrial nucleoid1IDAHomo_sapiens(9606)Component
GO:0043565enables sequence-specific DNA binding1IDAHomo_sapiens(9606)Function

Expression