Ensembl ID ENSG00000099821 Gene ID 5442 Accession 9200
Gene Symbol POLRMT Alias APOLMT;MTRNAP;MTRPOL;COXPD55;h-mtRPOL Full Name RNA polymerase mitochondrial
Position 19 : 617221 - 633537 Length 16317 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]

ENSG00000099821 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000099821 POLRMT 0.50 1.17e-16 BRCA
ENSG00000099821 POLRMT 0.77 3.08e-13 KICH
ENSG00000099821 POLRMT 0.65 2.75e-14 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000099821 POLRMT tumor 23070475
ENSG00000099821 POLRMT breast cancer 23172368
ENSG00000099821 POLRMT oral cancer 26403317
ENSG00000099821 POLRMT AML 26484416
ENSG00000099821 POLRMT cancer 27590350
ENSG00000099821 POLRMT cancer 29435159
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000099821 POLRMT STAD 0.001 low
ENSG00000099821 POLRMT PAAD 9e-04 low
ENSG00000099821 POLRMT UCEC 0.00037 low
ENSG00000099821 POLRMT ACC 0.0022 high
ENSG00000099821 POLRMT LUSC 0.04 low
ENSG00000099821 POLRMT HNSC 0.03 low
ENSG00000099821 POLRMT READ 0.0077 low
ENSG00000099821 POLRMT PCPG 0.00012 high
ENSG00000099821 POLRMT THYM 0.0094 low
ENSG00000099821 POLRMT COAD 0.0099 high
ENSG00000099821 POLRMT UCS 0.038 high
ENSG00000099821 POLRMT ESCA 0.0041 low
ENSG00000099821 POLRMT DLBC 0.003 low
ENSG00000099821 POLRMT BLCA 0.012 low
ENSG00000099821 POLRMT LAML 0.018 high
ENSG00000099821 POLRMT GBM 0.019 low
ENSG00000099821 POLRMT SKCM 0.011 high
ENSG00000099821 POLRMT CESC 0.032 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000099821 POLRMT LUSC Del 11.405771 0.159264 0.361782 0.469062
ENSG00000099821 POLRMT LUAD Del 5.356397 0.095886 0.354775 0.534884
ENSG00000099821 POLRMT LGG Amp 2.465343 0.069482 0.348686 0.247563
ENSG00000099821 POLRMT CESC Del 15.811005 0.223136 0.490602 0.349153
ENSG00000099821 POLRMT READ Del 0.637830 0.068240 0.352942 0.206061
ENSG00000099821 POLRMT COAD Del 2.155640 0.057613 0.389840 0.133038
ENSG00000099821 POLRMT UCS Del 13.285308 0.839054 0.638449 0.839286
ENSG00000099821 POLRMT SARC Del 5.546917 0.225798 0.489854 0.237354
ENSG00000099821 POLRMT GBM Amp 1.293997 0.078680 0.541549 0.422877
ENSG00000099821 POLRMT PAAD Del 1.977711 0.070608 0.352873 0.195652
ENSG00000099821 POLRMT ESCA Del 3.974428 0.177696 0.356935 0.505435
ENSG00000099821 POLRMT SKCM Del 1.625897 0.081125 0.340586 0.283379
ENSG00000099821 POLRMT HNSC Del 15.441982 0.149746 0.362801 0.329502
ENSG00000099821 POLRMT LIHC Del 6.102569 0.132551 0.460252 0.245946
ENSG00000099821 POLRMT BLCA Del 5.931746 0.143027 0.342924 0.352941
ENSG00000099821 POLRMT BRCA Del 30.100615 0.177234 0.407156 0.334259
ENSG00000099821 POLRMT STAD Del 1.560167 0.072913 0.346299 0.335601
ENSG00000099821 POLRMT UCEC Del 41.677202 0.252685 0.593975 0.267161
ENSG00000099821 POLRMT OV Del 136.511127 0.942410 0.655899 0.872193