RBP Type	Canonical_RBPs
Diseases	CancerCHIKVSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granucleP-body
BulkPerturb-seq	DataSet_01_104 DataSet_01_414

Ensembl ID	ENSG00000099783	Gene ID	4670	Accession	5046
Symbol	HNRNPM	Alias	CEAR;HNRPM;HTGR1;NAGR1;HNRPM4;HNRNPM4;hnRNPM	Full Name	heterogeneous nuclear ribonucleoprotein M
Status	Confidence	Length	44348 bases	Strand	Plus strand
Position	19 : 8444767 - 8489114	RNA binding domain	RRM_1 , HnRNP_M_NLS
Summary	This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000325732	RRM_1	PF00076	4.8e-52	1
ENSP00000325732	RRM_1	PF00076	4.8e-52	2
ENSP00000325732	RRM_1	PF00076	4.8e-52	3
ENSP00000325732	HnRNP_M_NLS	PF11532	2.6e-17	4
ENSP00000325376	RRM_1	PF00076	5.9e-52	1
ENSP00000325376	RRM_1	PF00076	5.9e-52	2
ENSP00000325376	RRM_1	PF00076	5.9e-52	3
ENSP00000325376	HnRNP_M_NLS	PF11532	2.8e-17	4
ENSP00000483715	RRM_1	PF00076	2.4e-49	1
ENSP00000483715	RRM_1	PF00076	2.4e-49	2
ENSP00000483715	RRM_1	PF00076	2.4e-49	3
ENSP00000483715	HnRNP_M_NLS	PF11532	2.8e-17	4
ENSP00000470932	RRM_1	PF00076	2e-31	1
ENSP00000470932	RRM_1	PF00076	2e-31	2
ENSP00000470932	HnRNP_M_NLS	PF11532	9.9e-18	3
ENSP00000472789	RRM_1	PF00076	2.1e-31	1
ENSP00000472789	RRM_1	PF00076	2.1e-31	2
ENSP00000472789	HnRNP_M_NLS	PF11532	1e-17	3
ENSP00000471339	RRM_1	PF00076	4.1e-29	1
ENSP00000471339	RRM_1	PF00076	4.1e-29	2
ENSP00000471339	HnRNP_M_NLS	PF11532	7.9e-18	3
ENSP00000470017	RRM_1	PF00076	8.9e-23	1
ENSP00000470017	HnRNP_M_NLS	PF11532	4.7e-18	2
ENSP00000470635	RRM_1	PF00076	1.2e-09	1
ENSP00000469681	RRM_1	PF00076	0.0003	1
ENSP00000472599	RRM_1	PF00076	0.0011	1
ENSP00000471530	HnRNP_M_NLS	PF11532	3.2e-18	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
30852162	hnRNPM induces translation switch under hypoxia to promote colon cancer development.	Tsung-Ming Chen	2019-03-01	EBioMedicine
31803364	Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study.	Andro Košec	2019-11-19	Oncotarget
32023846	Poison-Exon Inclusion in DHX9 Reduces Its Expression and Sensitizes Ewing Sarcoma Cells to Chemotherapeutic Treatment.	Ramona Palombo	2020-01-31	Cells
29675578	The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.	Mariaelena Repici	2019-01-01	Molecular neurobiology
32811564	RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM.	Nandini Ramesh	2020-08-18	Acta neuropathologica communications
28716093	C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility.	L Wendy Johnston	2017-07-17	BMC biology
30813302	The Relevance of Toxic AGEs (TAGE) Cytotoxicity to NASH Pathogenesis: A Mini-Review.	Akiko Sakasai-Sakai	2019-02-22	Nutrients
36865202	LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity.	Rong Zheng	2023-02-24	bioRxiv : the preprint server for biology
33466816	Alterations in Glucose Metabolism Due to Decreased Expression of Heterogeneous Nuclear Ribonucleoprotein M in Pancreatic Ductal Adenocarcinoma.	Jun-Ichi Takino	2021-01-14	Biology
31980632	The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing.	Xiaohui Hu	2020-01-24	Nature communications
37016304	Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer's disease.	S Ravi Pandey	2023-04-04	BMC genomics
24840202	Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing.	Yilin Xu	2014-06-01	Genes & development
36417528	Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease.	Qiong Liu	2022-11-25	Science advances
32732889	Targeting QKI-7 in vivo restores endothelial cell function in diabetes.	Chunbo Yang	2020-07-30	Nature communications
35732702	SILAC kinase screen identifies potential MASTL substrates.	A Kamila Marzec	2022-06-22	Scientific reports
30042172	Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT.	E Samuel Harvey	2018-10-01	RNA (New York, N.Y.)
31737791	Contribution of alternative splicing to breast cancer metastasis.	Xiangbing Meng	2019-01-01	Journal of cancer metastasis and treatment
36978995	Involvement of Intracellular TAGE and the TAGE-RAGE-ROS Axis in the Onset and Progression of NAFLD/NASH.	Akiko Sakasai-Sakai	2023-03-19	Antioxidants (Basel, Switzerland)
36930678	PCB: A pseudotemporal causality-based Bayesian approach to identify EMT-associated regulatory relationships of AS events and RBPs during breast cancer progression.	Liangjie Sun	2023-03-01	PLoS computational biology
35883620	Effects of Toxic AGEs (TAGE) on Human Health.	Masayoshi Takeuchi	2022-07-12	Cells
36620748	Epigenetic regulation of dental-derived stem cells and their application in pulp and periodontal regeneration.	Yuyang Chen	2023-01-01	PeerJ

Name	Transcript ID	bp	Protein	Translation ID
HNRNPM-202	ENST00000348943	2568	691aa	ENSP00000325732
HNRNPM-209	ENST00000597813	630	No protein	-
HNRNPM-213	ENST00000600092	1086	352aa	ENSP00000470932
HNRNPM-201	ENST00000325495	2477	730aa	ENSP00000325376
HNRNPM-214	ENST00000600806	2373	99aa	ENSP00000471530
HNRNPM-204	ENST00000594907	1078	357aa	ENSP00000472789
HNRNPM-206	ENST00000596984	664	219aa	ENSP00000470017
HNRNPM-215	ENST00000601645	832	275aa	ENSP00000471339
HNRNPM-203	ENST00000593293	764	No protein	-
HNRNPM-210	ENST00000598367	298	99aa	ENSP00000469906
HNRNPM-208	ENST00000597270	1147	383aa	ENSP00000470635
HNRNPM-207	ENST00000597081	1004	No protein	-
HNRNPM-211	ENST00000598603	784	No protein	-
HNRNPM-205	ENST00000596295	910	214aa	ENSP00000472599
HNRNPM-212	ENST00000598999	409	116aa	ENSP00000469681
HNRNPM-216	ENST00000602219	1809	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
34007	Tunica Media	8.9730861E-005	-
52923	Interleukin 1 Receptor Antagonist Protein	5.8410000E-005	-
52931	Interleukin 1 Receptor Antagonist Protein	4.8500000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000099783	homo_sapiens	ENSP00000316950	67	53.5	homo_sapiens	ENSP00000325376	55.0685	43.9726

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000099783	homo_sapiens	ENSP00000325376	13.0137	13.0137	nomascus_leucogenys	ENSNLEP00000002256	95	95
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.589	pan_paniscus	ENSPPAP00000033281	99.589	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	100	99.863	pongo_abelii	ENSPPYP00000010664	100	99.863
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.589	pan_troglodytes	ENSPTRP00000017736	99.589	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.589	gorilla_gorilla	ENSGGOP00000018014	99.589	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	88.9041	83.2877	ornithorhynchus_anatinus	ENSOANP00000009364	88.7825	83.1737
ENSG00000099783	homo_sapiens	ENSP00000325376	95.2055	90.6849	sarcophilus_harrisii	ENSSHAP00000034485	93.5397	89.0983
ENSG00000099783	homo_sapiens	ENSP00000325376	91.7808	87.2603	notamacropus_eugenii	ENSMEUP00000004376	92.2865	87.741
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.4931	choloepus_hoffmanni	ENSCHOP00000012063	99.0411	98.4931
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.6301	dasypus_novemcinctus	ENSDNOP00000009444	87.1084	86.747
ENSG00000099783	homo_sapiens	ENSP00000325376	47.2603	43.1507	erinaceus_europaeus	ENSEEUP00000001770	63.4191	57.9044
ENSG00000099783	homo_sapiens	ENSP00000325376	96.0274	95.0685	echinops_telfairi	ENSETEP00000016014	96.0274	95.0685
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	callithrix_jacchus	ENSCJAP00000020089	99.589	99.4521
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.589	cercocebus_atys	ENSCATP00000024136	99.589	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	99.0411	macaca_fascicularis	ENSMFAP00000045533	99.4498	99.4498
ENSG00000099783	homo_sapiens	ENSP00000325376	100	100	macaca_mulatta	ENSMMUP00000024753	100	100
ENSG00000099783	homo_sapiens	ENSP00000325376	100	100	macaca_nemestrina	ENSMNEP00000026791	100	100
ENSG00000099783	homo_sapiens	ENSP00000325376	100	100	papio_anubis	ENSPANP00000009850	100	100
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.589	mandrillus_leucophaeus	ENSMLEP00000036242	99.589	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	94.9315	94.7945	tursiops_truncatus	ENSTTRP00000009268	94.9315	94.7945
ENSG00000099783	homo_sapiens	ENSP00000325376	92.6027	91.9178	vulpes_vulpes	ENSVVUP00000034990	89.6552	88.992
ENSG00000099783	homo_sapiens	ENSP00000325376	98.3562	97.6712	mus_spretus	MGP_SPRETEiJ_P0045909	98.4911	97.8052
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	equus_asinus	ENSEASP00005032819	91.3317	91.206
ENSG00000099783	homo_sapiens	ENSP00000325376	93.9726	93.6986	capra_hircus	ENSCHIP00000032304	99.2764	98.987
ENSG00000099783	homo_sapiens	ENSP00000325376	97.8082	96.7123	loxodonta_africana	ENSLAFP00000011385	98.0769	96.978
ENSG00000099783	homo_sapiens	ENSP00000325376	99.4521	99.3151	panthera_leo	ENSPLOP00000000932	99.4521	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	99.4521	99.3151	ailuropoda_melanoleuca	ENSAMEP00000005281	99.4521	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	bos_indicus_hybrid	ENSBIXP00005030288	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	85.6164	85.0685	oryctolagus_cuniculus	ENSOCUP00000023086	98.4252	97.7953
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	equus_caballus	ENSECAP00000081627	91.3317	91.206
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.9041	canis_lupus_familiaris	ENSCAFP00845008810	92.4552	92.3274
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.9041	panthera_pardus	ENSPPRP00000017187	99.0411	98.9041
ENSG00000099783	homo_sapiens	ENSP00000325376	96.4384	96.3014	marmota_marmota_marmota	ENSMMMP00000024693	96.4384	96.3014
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	balaenoptera_musculus	ENSBMSP00010018161	99.589	99.4521
ENSG00000099783	homo_sapiens	ENSP00000325376	99.3151	98.4931	cavia_porcellus	ENSCPOP00000031827	99.3151	98.4931
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.9041	felis_catus	ENSFCAP00000014117	99.0411	98.9041
ENSG00000099783	homo_sapiens	ENSP00000325376	97.1233	96.7123	ursus_americanus	ENSUAMP00000007688	91.8394	91.4508
ENSG00000099783	homo_sapiens	ENSP00000325376	43.4247	41.3699	monodelphis_domestica	ENSMODP00000004247	87.0879	82.967
ENSG00000099783	homo_sapiens	ENSP00000325376	90.411	86.0274	monodelphis_domestica	ENSMODP00000004654	98.2143	93.4524
ENSG00000099783	homo_sapiens	ENSP00000325376	94.2466	93.9726	bison_bison_bison	ENSBBBP00000011661	94.2466	93.9726
ENSG00000099783	homo_sapiens	ENSP00000325376	90.137	88.4931	monodon_monoceros	ENSMMNP00015027556	84.359	82.8205
ENSG00000099783	homo_sapiens	ENSP00000325376	93.9726	93.6986	sus_scrofa	ENSSSCP00000014455	84.2752	84.0295
ENSG00000099783	homo_sapiens	ENSP00000325376	91.9178	91.3699	microcebus_murinus	ENSMICP00000002312	89.1102	88.579
ENSG00000099783	homo_sapiens	ENSP00000325376	12.4658	12.1918	octodon_degus	ENSODEP00000011424	86.6667	84.7619
ENSG00000099783	homo_sapiens	ENSP00000325376	83.8356	80.8219	octodon_degus	ENSODEP00000012383	92.0301	88.7218
ENSG00000099783	homo_sapiens	ENSP00000325376	12.6027	12.1918	octodon_degus	ENSODEP00000014514	93.8775	90.8163
ENSG00000099783	homo_sapiens	ENSP00000325376	13.8356	13.5616	octodon_degus	ENSODEP00000023709	99.0196	97.0588
ENSG00000099783	homo_sapiens	ENSP00000325376	98.3562	97.3973	jaculus_jaculus	ENSJJAP00000015087	98.3562	97.3973
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	ovis_aries_rambouillet	ENSOARP00020017252	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	76.4384	75.8904	ursus_maritimus	ENSUMAP00000019910	99.1119	98.4014
ENSG00000099783	homo_sapiens	ENSP00000325376	65.0685	63.9726	ochotona_princeps	ENSOPRP00000001806	68.8406	67.6812
ENSG00000099783	homo_sapiens	ENSP00000325376	94.1096	93.9726	delphinapterus_leucas	ENSDLEP00000019022	94.8895	94.7514
ENSG00000099783	homo_sapiens	ENSP00000325376	94.6575	94.5205	physeter_catodon	ENSPCTP00005010954	99.8555	99.711
ENSG00000099783	homo_sapiens	ENSP00000325376	98.3562	97.8082	mus_caroli	MGP_CAROLIEiJ_P0044005	98.4911	97.9424
ENSG00000099783	homo_sapiens	ENSP00000325376	98.3562	97.5342	mus_musculus	ENSMUSP00000120115	98.4911	97.668
ENSG00000099783	homo_sapiens	ENSP00000325376	99.4521	99.0411	dipodomys_ordii	ENSDORP00000007605	99.4521	99.0411
ENSG00000099783	homo_sapiens	ENSP00000325376	93.8356	93.6986	mustela_putorius_furo	ENSMPUP00000007183	85.3051	85.1806
ENSG00000099783	homo_sapiens	ENSP00000325376	99.726	99.726	aotus_nancymaae	ENSANAP00000015039	99.726	99.726
ENSG00000099783	homo_sapiens	ENSP00000325376	99.3151	99.1781	saimiri_boliviensis_boliviensis	ENSSBOP00000032916	99.3151	99.1781
ENSG00000099783	homo_sapiens	ENSP00000325376	81.6438	81.3699	vicugna_pacos	ENSVPAP00000003916	88.6905	88.3929
ENSG00000099783	homo_sapiens	ENSP00000325376	91.6438	90.8219	chlorocebus_sabaeus	ENSCSAP00000004250	96.6763	95.8092
ENSG00000099783	homo_sapiens	ENSP00000325376	66.4384	66.1644	tupaia_belangeri	ENSTBEP00000007557	70.9064	70.614
ENSG00000099783	homo_sapiens	ENSP00000325376	98.9041	98.3562	mesocricetus_auratus	ENSMAUP00000019160	98.9041	98.3562
ENSG00000099783	homo_sapiens	ENSP00000325376	99.726	99.589	phocoena_sinus	ENSPSNP00000018007	99.726	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	99.726	99.589	camelus_dromedarius	ENSCDRP00005015346	99.726	99.589
ENSG00000099783	homo_sapiens	ENSP00000325376	83.9726	82.0548	carlito_syrichta	ENSTSYP00000031573	93.4451	91.311
ENSG00000099783	homo_sapiens	ENSP00000325376	90.9589	90.8219	panthera_tigris_altaica	ENSPTIP00000001275	94.3182	94.1761
ENSG00000099783	homo_sapiens	ENSP00000325376	13.6986	12.6027	rattus_norvegicus	ENSRNOP00000069439	72.9927	67.1533
ENSG00000099783	homo_sapiens	ENSP00000325376	35.3425	33.8356	prolemur_simus	ENSPSMP00000008223	94.1606	90.146
ENSG00000099783	homo_sapiens	ENSP00000325376	98.6301	98.0822	microtus_ochrogaster	ENSMOCP00000006210	98.6301	98.0822
ENSG00000099783	homo_sapiens	ENSP00000325376	71.2329	70.6849	sorex_araneus	ENSSARP00000000242	71.1354	70.5882
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	98.4931	peromyscus_maniculatus_bairdii	ENSPEMP00000007356	99.0411	98.4931
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	bos_mutus	ENSBMUP00000034613	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	92.7397	92.0548	mus_spicilegus	ENSMSIP00000009793	87.9221	87.2727
ENSG00000099783	homo_sapiens	ENSP00000325376	69.863	69.1781	cricetulus_griseus_chok1gshd	ENSCGRP00001010047	92.3913	91.4855
ENSG00000099783	homo_sapiens	ENSP00000325376	12.8767	12.6027	cricetulus_griseus_chok1gshd	ENSCGRP00001022820	94	92
ENSG00000099783	homo_sapiens	ENSP00000325376	89.0411	88.7671	pteropus_vampyrus	ENSPVAP00000009094	98.6343	98.3308
ENSG00000099783	homo_sapiens	ENSP00000325376	93.8356	93.5616	myotis_lucifugus	ENSMLUP00000006124	97.3011	97.017
ENSG00000099783	homo_sapiens	ENSP00000325376	72.0548	71.3699	myotis_lucifugus	ENSMLUP00000017750	94.0966	93.2021
ENSG00000099783	homo_sapiens	ENSP00000325376	92.4658	88.0822	vombatus_ursinus	ENSVURP00010032413	97.4026	92.785
ENSG00000099783	homo_sapiens	ENSP00000325376	68.3562	67.3973	rhinolophus_ferrumequinum	ENSRFEP00010014807	97.4609	96.0938
ENSG00000099783	homo_sapiens	ENSP00000325376	99.4521	99.1781	neovison_vison	ENSNVIP00000021962	99.4521	99.1781
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	bos_taurus	ENSBTAP00000074476	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	13.9726	13.0137	heterocephalus_glaber_female	ENSHGLP00000006365	77.8626	72.5191
ENSG00000099783	homo_sapiens	ENSP00000325376	90.5479	90	rhinopithecus_bieti	ENSRBIP00000035755	99.5482	98.9458
ENSG00000099783	homo_sapiens	ENSP00000325376	95.0685	94.5205	canis_lupus_dingo	ENSCAFP00020028289	88.6335	88.1226
ENSG00000099783	homo_sapiens	ENSP00000325376	30.137	30.137	sciurus_vulgaris	ENSSVLP00005008239	100	100
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	sciurus_vulgaris	ENSSVLP00005024085	99.589	99.4521
ENSG00000099783	homo_sapiens	ENSP00000325376	14.1096	13.5616	sciurus_vulgaris	ENSSVLP00005008223	82.4	79.2
ENSG00000099783	homo_sapiens	ENSP00000325376	90.411	86.0274	phascolarctos_cinereus	ENSPCIP00000027132	98.2143	93.4524
ENSG00000099783	homo_sapiens	ENSP00000325376	98.6301	97.2603	procavia_capensis	ENSPCAP00000009046	98.6301	97.2603
ENSG00000099783	homo_sapiens	ENSP00000325376	69.1781	64.9315	nannospalax_galili	ENSNGAP00000017150	89.698	84.1918
ENSG00000099783	homo_sapiens	ENSP00000325376	10.5479	9.58904	nannospalax_galili	ENSNGAP00000004176	88.5057	80.4598
ENSG00000099783	homo_sapiens	ENSP00000325376	92.6027	91.2329	bos_grunniens	ENSBGRP00000040208	91.1051	89.7574
ENSG00000099783	homo_sapiens	ENSP00000325376	75.2055	70.9589	chinchilla_lanigera	ENSCLAP00000004287	88.5484	83.5484
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	cervus_hanglu_yarkandensis	ENSCHYP00000017631	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	catagonus_wagneri	ENSCWAP00000022327	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.4521	ictidomys_tridecemlineatus	ENSSTOP00000029033	99.589	99.4521
ENSG00000099783	homo_sapiens	ENSP00000325376	40.137	37.1233	otolemur_garnettii	ENSOGAP00000021070	88.5196	81.8731
ENSG00000099783	homo_sapiens	ENSP00000325376	99.0411	99.0411	cebus_imitator	ENSCCAP00000004462	99.5868	99.5868
ENSG00000099783	homo_sapiens	ENSP00000325376	96.9863	96.8493	urocitellus_parryii	ENSUPAP00010005847	90.653	90.525
ENSG00000099783	homo_sapiens	ENSP00000325376	88.3562	88.0822	moschus_moschiferus	ENSMMSP00000006031	98.9264	98.6196
ENSG00000099783	homo_sapiens	ENSP00000325376	99.589	99.3151	moschus_moschiferus	ENSMMSP00000004741	99.589	99.3151
ENSG00000099783	homo_sapiens	ENSP00000325376	99.3151	99.1781	rhinopithecus_roxellana	ENSRROP00000029024	99.3151	99.1781
ENSG00000099783	homo_sapiens	ENSP00000325376	92.0548	91.9178	rhinopithecus_roxellana	ENSRROP00000018242	98.2456	98.0994
ENSG00000099783	homo_sapiens	ENSP00000325376	98.2192	97.6712	mus_pahari	MGP_PahariEiJ_P0043562	98.3539	97.8052
ENSG00000099783	homo_sapiens	ENSP00000325376	93.5616	93.1507	propithecus_coquereli	ENSPCOP00000016976	90.5836	90.1857
ENSG00000099783	homo_sapiens	ENSP00000325376	29.589	21.3699	caenorhabditis_elegans	C25A1.4.1	47.5771	34.3612
ENSG00000099783	homo_sapiens	ENSP00000325376	36.7123	25.4795	drosophila_melanogaster	FBpp0081601	42.4051	29.4304
ENSG00000099783	homo_sapiens	ENSP00000325376	36.5753	24.6575	ciona_intestinalis	ENSCINP00000028897	52.4558	35.3635
ENSG00000099783	homo_sapiens	ENSP00000325376	55.2055	43.9726	callorhinchus_milii	ENSCMIP00000021095	68.0743	54.223
ENSG00000099783	homo_sapiens	ENSP00000325376	61.5069	48.0822	latimeria_chalumnae	ENSLACP00000019111	72.4194	56.6129
ENSG00000099783	homo_sapiens	ENSP00000325376	68.3562	55.7534	lepisosteus_oculatus	ENSLOCP00000005330	76.2997	62.2324
ENSG00000099783	homo_sapiens	ENSP00000325376	61.9178	51.7808	clupea_harengus	ENSCHAP00000043344	69.5385	58.1538
ENSG00000099783	homo_sapiens	ENSP00000325376	66.3014	54.2466	danio_rerio	ENSDARP00000121443	67.6923	55.3846
ENSG00000099783	homo_sapiens	ENSP00000325376	66.8493	54.9315	carassius_auratus	ENSCARP00000024746	72.619	59.6726
ENSG00000099783	homo_sapiens	ENSP00000325376	66.7123	54.7945	carassius_auratus	ENSCARP00000084714	70.2742	57.7201
ENSG00000099783	homo_sapiens	ENSP00000325376	66.8493	54.9315	carassius_auratus	ENSCARP00000018407	72.619	59.6726
ENSG00000099783	homo_sapiens	ENSP00000325376	64.9315	53.8356	astyanax_mexicanus	ENSAMXP00000016570	70.1183	58.1361
ENSG00000099783	homo_sapiens	ENSP00000325376	65.0685	53.8356	ictalurus_punctatus	ENSIPUP00000037516	72.8528	60.2761
ENSG00000099783	homo_sapiens	ENSP00000325376	64.1096	53.6986	esox_lucius	ENSELUP00000040503	69.5394	58.2467
ENSG00000099783	homo_sapiens	ENSP00000325376	63.0137	52.0548	electrophorus_electricus	ENSEEEP00000035104	69.8027	57.6631
ENSG00000099783	homo_sapiens	ENSP00000325376	62.7397	52.6027	oncorhynchus_kisutch	ENSOKIP00005014993	68.8722	57.7444
ENSG00000099783	homo_sapiens	ENSP00000325376	63.8356	53.5616	oncorhynchus_kisutch	ENSOKIP00005007722	71.4724	59.9693
ENSG00000099783	homo_sapiens	ENSP00000325376	64.3836	53.5616	oncorhynchus_mykiss	ENSOMYP00000117730	67.7233	56.3401
ENSG00000099783	homo_sapiens	ENSP00000325376	63.8356	52.7397	oncorhynchus_mykiss	ENSOMYP00000036188	69.8651	57.7211
ENSG00000099783	homo_sapiens	ENSP00000325376	65.6164	55.0685	salmo_salar	ENSSSAP00000062775	71.9219	60.3604
ENSG00000099783	homo_sapiens	ENSP00000325376	64.7945	53.8356	salmo_salar	ENSSSAP00000167292	69.764	57.9646
ENSG00000099783	homo_sapiens	ENSP00000325376	62.7397	51.7808	salmo_trutta	ENSSTUP00000023405	70.4615	58.1538
ENSG00000099783	homo_sapiens	ENSP00000325376	63.2877	53.1507	salmo_trutta	ENSSTUP00000093252	69.3694	58.2583
ENSG00000099783	homo_sapiens	ENSP00000325376	59.1781	47.9452	gadus_morhua	ENSGMOP00000010398	67.5	54.6875
ENSG00000099783	homo_sapiens	ENSP00000325376	65.3425	54.5205	fundulus_heteroclitus	ENSFHEP00000005726	68.2403	56.9385
ENSG00000099783	homo_sapiens	ENSP00000325376	65.7534	54.2466	poecilia_reticulata	ENSPREP00000023868	66.39	54.7718
ENSG00000099783	homo_sapiens	ENSP00000325376	58.3562	47.6712	xiphophorus_maculatus	ENSXMAP00000037770	67.4051	55.0633
ENSG00000099783	homo_sapiens	ENSP00000325376	62.7397	52.1918	oryzias_latipes	ENSORLP00000028445	68.5629	57.0359
ENSG00000099783	homo_sapiens	ENSP00000325376	63.6986	52.3288	cyclopterus_lumpus	ENSCLMP00005049231	67.1965	55.2023
ENSG00000099783	homo_sapiens	ENSP00000325376	65.6164	55.0685	oreochromis_niloticus	ENSONIP00000002202	70.5449	59.2047
ENSG00000099783	homo_sapiens	ENSP00000325376	63.9726	53.6986	haplochromis_burtoni	ENSHBUP00000035324	72.0679	60.4938
ENSG00000099783	homo_sapiens	ENSP00000325376	62.8767	52.4658	astatotilapia_calliptera	ENSACLP00000030503	69.4402	57.9425
ENSG00000099783	homo_sapiens	ENSP00000325376	66.1644	54.5205	sparus_aurata	ENSSAUP00010067674	68.8034	56.6952
ENSG00000099783	homo_sapiens	ENSP00000325376	62.3288	50.137	lates_calcarifer	ENSLCAP00010050048	64.0845	51.5493
ENSG00000099783	homo_sapiens	ENSP00000325376	74.2466	60	xenopus_tropicalis	ENSXETP00000003692	72.8495	58.871
ENSG00000099783	homo_sapiens	ENSP00000325376	9.45205	8.35616	chrysemys_picta_bellii	ENSCPBP00000023921	83.1325	73.494
ENSG00000099783	homo_sapiens	ENSP00000325376	75.0685	67.1233	chrysemys_picta_bellii	ENSCPBP00000023919	88.6731	79.288
ENSG00000099783	homo_sapiens	ENSP00000325376	80.5479	71.2329	sphenodon_punctatus	ENSSPUP00000002943	86.3436	76.3583
ENSG00000099783	homo_sapiens	ENSP00000325376	76.3014	66.0274	laticauda_laticaudata	ENSLLTP00000000655	84.139	72.8097
ENSG00000099783	homo_sapiens	ENSP00000325376	43.4247	35.0685	notechis_scutatus	ENSNSUP00000001299	79.4486	64.1604
ENSG00000099783	homo_sapiens	ENSP00000325376	43.4247	35.0685	notechis_scutatus	ENSNSUP00000001296	79.4486	64.1604
ENSG00000099783	homo_sapiens	ENSP00000325376	25.2055	20	notechis_scutatus	ENSNSUP00000001286	88.4615	70.1923
ENSG00000099783	homo_sapiens	ENSP00000325376	25.2055	20	notechis_scutatus	ENSNSUP00000001291	88.4615	70.1923
ENSG00000099783	homo_sapiens	ENSP00000325376	74.5205	63.9726	pseudonaja_textilis	ENSPTXP00000023743	83.4356	71.6258
ENSG00000099783	homo_sapiens	ENSP00000325376	79.589	70.5479	anas_platyrhynchos_platyrhynchos	ENSAPLP00000009883	84.8175	75.1825
ENSG00000099783	homo_sapiens	ENSP00000325376	88.3562	79.4521	gallus_gallus	ENSGALP00010042185	83.5492	75.1295
ENSG00000099783	homo_sapiens	ENSP00000325376	85.3425	76.8493	meleagris_gallopavo	ENSMGAP00000000090	93.4033	84.1079
ENSG00000099783	homo_sapiens	ENSP00000325376	74.5205	66.5753	serinus_canaria	ENSSCAP00000017284	79.1849	70.7424
ENSG00000099783	homo_sapiens	ENSP00000325376	80.6849	71.9178	parus_major	ENSPMJP00000017059	83.6648	74.5739
ENSG00000099783	homo_sapiens	ENSP00000325376	66.1644	55.3425	neolamprologus_brichardi	ENSNBRP00000020916	70.8211	59.2375
ENSG00000099783	homo_sapiens	ENSP00000325376	84.3836	73.4247	naja_naja	ENSNNAP00000004271	82.9071	72.14
ENSG00000099783	homo_sapiens	ENSP00000325376	76.1644	65.4795	podarcis_muralis	ENSPMRP00000034664	86.6044	74.4548
ENSG00000099783	homo_sapiens	ENSP00000325376	12.8767	10.9589	podarcis_muralis	ENSPMRP00000034650	58.0247	49.3827
ENSG00000099783	homo_sapiens	ENSP00000325376	66.5753	60.8219	geospiza_fortis	ENSGFOP00000013235	86.631	79.1444
ENSG00000099783	homo_sapiens	ENSP00000325376	85.8904	77.2603	taeniopygia_guttata	ENSTGUP00000000966	72.3183	65.0519
ENSG00000099783	homo_sapiens	ENSP00000325376	65.0685	53.9726	erpetoichthys_calabaricus	ENSECRP00000030671	73.9875	61.3707
ENSG00000099783	homo_sapiens	ENSP00000325376	65.7534	54.2466	kryptolebias_marmoratus	ENSKMAP00000029947	69.5652	57.3913
ENSG00000099783	homo_sapiens	ENSP00000325376	71.2329	61.0959	salvator_merianae	ENSSMRP00000025223	85.8086	73.5974
ENSG00000099783	homo_sapiens	ENSP00000325376	12.1918	11.0959	salvator_merianae	ENSSMRP00000025224	62.2378	56.6434
ENSG00000099783	homo_sapiens	ENSP00000325376	62.8767	52.8767	oryzias_javanicus	ENSOJAP00000042909	71.2733	59.9379
ENSG00000099783	homo_sapiens	ENSP00000325376	66.4384	55.7534	amphilophus_citrinellus	ENSACIP00000015424	71.1144	59.6774
ENSG00000099783	homo_sapiens	ENSP00000325376	66.7123	54.9315	dicentrarchus_labrax	ENSDLAP00005015305	69.1761	56.9602
ENSG00000099783	homo_sapiens	ENSP00000325376	66.8493	55.0685	amphiprion_percula	ENSAPEP00000005922	71.5543	58.9443
ENSG00000099783	homo_sapiens	ENSP00000325376	65.7534	54.5205	oryzias_sinensis	ENSOSIP00000010950	69.7674	57.8488
ENSG00000099783	homo_sapiens	ENSP00000325376	79.863	72.4658	pelodiscus_sinensis	ENSPSIP00000012893	87.4063	79.3103
ENSG00000099783	homo_sapiens	ENSP00000325376	10.274	9.45205	gopherus_evgoodei	ENSGEVP00005023872	79.7872	73.4043
ENSG00000099783	homo_sapiens	ENSP00000325376	77.8082	68.9041	gopherus_evgoodei	ENSGEVP00005023906	86.7176	76.7939
ENSG00000099783	homo_sapiens	ENSP00000325376	56.8493	49.4521	chelonoidis_abingdonii	ENSCABP00000006081	89.6328	77.9698
ENSG00000099783	homo_sapiens	ENSP00000325376	10.411	9.45205	chelonoidis_abingdonii	ENSCABP00000004560	76.7677	69.697
ENSG00000099783	homo_sapiens	ENSP00000325376	51.5069	43.0137	seriola_dumerili	ENSSDUP00000002880	74.1617	61.9329
ENSG00000099783	homo_sapiens	ENSP00000325376	63.4247	52.1918	cottoperca_gobio	ENSCGOP00000027309	69.6241	57.2932
ENSG00000099783	homo_sapiens	ENSP00000325376	85.7534	77.2603	struthio_camelus_australis	ENSSCUP00000003050	93.7126	84.4311
ENSG00000099783	homo_sapiens	ENSP00000325376	81.3699	72.3288	anser_brachyrhynchus	ENSABRP00000014685	84.136	74.7875
ENSG00000099783	homo_sapiens	ENSP00000325376	61.5069	50.6849	gasterosteus_aculeatus	ENSGACP00000013576	68.6544	56.5749
ENSG00000099783	homo_sapiens	ENSP00000325376	64.5205	52.7397	cynoglossus_semilaevis	ENSCSEP00000023491	68.2609	55.7971
ENSG00000099783	homo_sapiens	ENSP00000325376	55.7534	45.6164	poecilia_formosa	ENSPFOP00000013730	70.1724	57.4138
ENSG00000099783	homo_sapiens	ENSP00000325376	67.3973	56.4384	myripristis_murdjan	ENSMMDP00005023358	70.3863	58.9413
ENSG00000099783	homo_sapiens	ENSP00000325376	66.5753	55.0685	sander_lucioperca	ENSSLUP00000043712	70.0288	57.9251
ENSG00000099783	homo_sapiens	ENSP00000325376	80.9589	72.4658	strigops_habroptila	ENSSHBP00005020070	87.426	78.2544
ENSG00000099783	homo_sapiens	ENSP00000325376	65.7534	54.3836	amphiprion_ocellaris	ENSAOCP00000005063	72.9483	60.3343
ENSG00000099783	homo_sapiens	ENSP00000325376	85.4795	77.2603	terrapene_carolina_triunguis	ENSTMTP00000026027	93.5532	84.5577
ENSG00000099783	homo_sapiens	ENSP00000325376	65.3425	54.7945	hucho_hucho	ENSHHUP00000047018	71.5142	59.97
ENSG00000099783	homo_sapiens	ENSP00000325376	64.6575	53.9726	hucho_hucho	ENSHHUP00000024992	70.1337	58.5438
ENSG00000099783	homo_sapiens	ENSP00000325376	64.3836	53.2877	betta_splendens	ENSBSLP00000033648	70.5706	58.4084
ENSG00000099783	homo_sapiens	ENSP00000325376	64.2466	53.9726	pygocentrus_nattereri	ENSPNAP00000032544	71.7125	60.2446
ENSG00000099783	homo_sapiens	ENSP00000325376	65.6164	54.2466	anabas_testudineus	ENSATEP00000013001	71.8141	59.3703
ENSG00000099783	homo_sapiens	ENSP00000325376	36.4384	24.6575	ciona_savignyi	ENSCSAVP00000001355	55.7652	37.7358
ENSG00000099783	homo_sapiens	ENSP00000325376	22.7397	14.1096	saccharomyces_cerevisiae	YCL011C	38.8759	24.1218
ENSG00000099783	homo_sapiens	ENSP00000325376	20.274	11.6438	saccharomyces_cerevisiae	YNL004W	32.5991	18.7225
ENSG00000099783	homo_sapiens	ENSP00000325376	63.0137	52.4658	seriola_lalandi_dorsalis	ENSSLDP00000021544	67.9468	56.5731
ENSG00000099783	homo_sapiens	ENSP00000325376	65.7534	53.6986	labrus_bergylta	ENSLBEP00000005894	67.3212	54.979
ENSG00000099783	homo_sapiens	ENSP00000325376	62.7397	52.3288	pundamilia_nyererei	ENSPNYP00000008768	68.8722	57.4436
ENSG00000099783	homo_sapiens	ENSP00000325376	65.0685	53.8356	mastacembelus_armatus	ENSMAMP00000008241	70.3704	58.2222
ENSG00000099783	homo_sapiens	ENSP00000325376	64.3836	53.2877	stegastes_partitus	ENSSPAP00000030869	71.8654	59.4801
ENSG00000099783	homo_sapiens	ENSP00000325376	63.9726	53.6986	oncorhynchus_tshawytscha	ENSOTSP00005071189	71.6258	60.1227
ENSG00000099783	homo_sapiens	ENSP00000325376	64.1096	53.5616	oncorhynchus_tshawytscha	ENSOTSP00005073704	70.0599	58.5329
ENSG00000099783	homo_sapiens	ENSP00000325376	60	48.9041	acanthochromis_polyacanthus	ENSAPOP00000021093	69.5238	56.6667
ENSG00000099783	homo_sapiens	ENSP00000325376	64.5205	52.3288	nothobranchius_furzeri	ENSNFUP00015054871	62.2193	50.4624
ENSG00000099783	homo_sapiens	ENSP00000325376	65.8904	53.8356	cyprinodon_variegatus	ENSCVAP00000017708	69.8113	57.0392
ENSG00000099783	homo_sapiens	ENSP00000325376	63.9726	53.2877	denticeps_clupeoides	ENSDCDP00000051722	70.9726	59.1185
ENSG00000099783	homo_sapiens	ENSP00000325376	66.1644	54.1096	larimichthys_crocea	ENSLCRP00005057632	68.608	56.108
ENSG00000099783	homo_sapiens	ENSP00000325376	65.3425	52.8767	takifugu_rubripes	ENSTRUP00000069160	69.1304	55.942
ENSG00000099783	homo_sapiens	ENSP00000325376	80.274	71.3699	ficedula_albicollis	ENSFALP00000001105	85.1744	75.7267
ENSG00000099783	homo_sapiens	ENSP00000325376	63.8356	52.3288	hippocampus_comes	ENSHCOP00000016203	72.3602	59.3168
ENSG00000099783	homo_sapiens	ENSP00000325376	67.5342	55.6164	cyprinus_carpio_carpio	ENSCCRP00000108934	73.4724	60.5067
ENSG00000099783	homo_sapiens	ENSP00000325376	67.1233	55.6164	cyprinus_carpio_carpio	ENSCCRP00000135164	73.3533	60.7784
ENSG00000099783	homo_sapiens	ENSP00000325376	82.8767	74.1096	coturnix_japonica	ENSCJPP00005006472	85.8156	76.7376
ENSG00000099783	homo_sapiens	ENSP00000325376	63.5616	52.1918	poecilia_latipinna	ENSPLAP00000008475	69.5652	57.1214
ENSG00000099783	homo_sapiens	ENSP00000325376	65.6164	53.1507	sinocyclocheilus_grahami	ENSSGRP00000056108	70.0292	56.7251
ENSG00000099783	homo_sapiens	ENSP00000325376	63.4247	51.6438	sinocyclocheilus_grahami	ENSSGRP00000108454	67.4927	54.9563
ENSG00000099783	homo_sapiens	ENSP00000325376	66.9863	56.1644	maylandia_zebra	ENSMZEP00005003236	70.1578	58.8235
ENSG00000099783	homo_sapiens	ENSP00000325376	64.2466	51.7808	tetraodon_nigroviridis	ENSTNIP00000018601	70	56.4179
ENSG00000099783	homo_sapiens	ENSP00000325376	65.4795	54.6575	paramormyrops_kingsleyae	ENSPKIP00000014164	73.8794	61.6692
ENSG00000099783	homo_sapiens	ENSP00000325376	65.2055	54.1096	scleropages_formosus	ENSSFOP00015013912	73.3436	60.8629
ENSG00000099783	homo_sapiens	ENSP00000325376	57.1233	43.8356	leptobrachium_leishanense	ENSLLEP00000007275	62.3318	47.8326
ENSG00000099783	homo_sapiens	ENSP00000325376	66.7123	55.2055	scophthalmus_maximus	ENSSMAP00000006457	68.4951	56.6807
ENSG00000099783	homo_sapiens	ENSP00000325376	66.1644	55.0685	oryzias_melastigma	ENSOMEP00000011752	69.1977	57.5931

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000380	involved_in alternative mRNA splicing, via spliceosome	1	IMP	Homo_sapiens(9606)	Process
GO:0000398	involved_in mRNA splicing, via spliceosome	1	IC	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	2	HDA,NAS	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005681	part_of spliceosomal complex	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IEA	Homo_sapiens(9606)	Component
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016363	located_in nuclear matrix	1	IDA	Homo_sapiens(9606)	Component
GO:0019904	enables protein domain specific binding	1	IPI	Homo_sapiens(9606)	Function
GO:0042382	located_in paraspeckles	1	IDA	Homo_sapiens(9606)	Component
GO:0045202	located_in synapse	1	IEA	Homo_sapiens(9606)	Component
GO:0062023	located_in collagen-containing extracellular matrix	1	HDA	Homo_sapiens(9606)	Component
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0071013	part_of catalytic step 2 spliceosome	1	IDA	Homo_sapiens(9606)	Component