Ensembl ID ENSG00000099783 Gene ID 4670 Accession 5046
Gene Symbol HNRNPM Alias CEAR;HNRPM;HTGR1;NAGR1;HNRPM4;HNRNPM4;hnRNPM Full Name heterogeneous nuclear ribonucleoprotein M
Position 19 : 8444767 - 8489114 Length 44348 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

ENSG00000099783 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000099783 HNRNPM 0.40 1.88e-26 BRCA
ENSG00000099783 HNRNPM 0.42 1.25e-13 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000099783 HNRNPM breast cancer 16280054
ENSG00000099783 HNRNPM cancer 23812426
ENSG00000099783 HNRNPM cancer 24381081
ENSG00000099783 HNRNPM breast cancer 24840202
ENSG00000099783 HNRNPM tumor 26273588
ENSG00000099783 HNRNPM breast cancer 26728853
ENSG00000099783 HNRNPM breast cancer 28393427
ENSG00000099783 HNRNPM epithelial ovarian cancer 28609484
ENSG00000099783 HNRNPM breast cancer 29036465
ENSG00000099783 HNRNPM breast cancer 30021377
ENSG00000099783 HNRNPM Triple-Negative Breast Cancer 30093560
ENSG00000099783 HNRNPM colorectal cancer 30852162
ENSG00000099783 HNRNPM prostate cancer 31251827
ENSG00000099783 HNRNPM breast cancer 31666932
ENSG00000099783 HNRNPM breast cancer 31737791
ENSG00000099783 HNRNPM Tumor 31803364
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000099783 HNRNPM MESO 0.016 high
ENSG00000099783 HNRNPM SARC 0.0075 high
ENSG00000099783 HNRNPM STAD 9e-04 low
ENSG00000099783 HNRNPM UVM 0.0036 low
ENSG00000099783 HNRNPM PAAD 0.014 low
ENSG00000099783 HNRNPM UCEC 0.02 low
ENSG00000099783 HNRNPM THCA 0.023 high
ENSG00000099783 HNRNPM HNSC 0.00019 low
ENSG00000099783 HNRNPM READ 0.0032 low
ENSG00000099783 HNRNPM KIRP 0.032 high
ENSG00000099783 HNRNPM KICH 0.04 high
ENSG00000099783 HNRNPM LUAD 0.02 high
ENSG00000099783 HNRNPM THYM 0.00094 low
ENSG00000099783 HNRNPM UCS 0.015 low
ENSG00000099783 HNRNPM ESCA 6e-04 high
ENSG00000099783 HNRNPM OV 0.012 low
ENSG00000099783 HNRNPM DLBC 0.0047 low
ENSG00000099783 HNRNPM KIRC 0.00023 low
ENSG00000099783 HNRNPM PRAD 0.005 high
ENSG00000099783 HNRNPM SKCM 0.025 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000099783 HNRNPM LUSC Del 1.069566 0.071096 0.337074 0.403194
ENSG00000099783 HNRNPM LUAD Del 0.760384 0.052034 0.337995 0.529070
ENSG00000099783 HNRNPM CESC Del 2.873041 0.103861 0.433016 0.291525
ENSG00000099783 HNRNPM UCS Del 4.293397 0.436927 0.598644 0.589286
ENSG00000099783 HNRNPM ESCA Del 1.472601 0.118856 0.330513 0.472826
ENSG00000099783 HNRNPM HNSC Del 2.288452 0.071140 0.321984 0.260536
ENSG00000099783 HNRNPM LIHC Del 4.642669 0.117628 0.457286 0.232432
ENSG00000099783 HNRNPM BRCA Del 0.680331 0.063054 0.348116 0.237963
ENSG00000099783 HNRNPM STAD Del 1.951969 0.077823 0.359715 0.344671
ENSG00000099783 HNRNPM UCEC Del 17.961561 0.159686 0.566170 0.194805
ENSG00000099783 HNRNPM OV Amp 1.122579 0.344373 0.746872 0.293610
ENSG00000099783 HNRNPM OV Del 16.493852 0.355835 0.576375 0.478411