Ensembl ID
ENSG00000099783
Gene ID
4670
Accession
5046
Gene Symbol
HNRNPM
Alias
CEAR;HNRPM;HTGR1;NAGR1;HNRPM4;HNRNPM4;hnRNPM
Full Name
heterogeneous nuclear ribonucleoprotein M
Position
19 : 8444767 - 8489114
Length
44348 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
ENSG00000099783 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000099783
HNRNPM
0.40
1.88e-26
BRCA
ENSG00000099783
HNRNPM
0.42
1.25e-13
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000099783
HNRNPM
breast cancer
16280054
ENSG00000099783
HNRNPM
cancer
23812426
ENSG00000099783
HNRNPM
cancer
24381081
ENSG00000099783
HNRNPM
breast cancer
24840202
ENSG00000099783
HNRNPM
tumor
26273588
ENSG00000099783
HNRNPM
breast cancer
26728853
ENSG00000099783
HNRNPM
breast cancer
28393427
ENSG00000099783
HNRNPM
epithelial ovarian cancer
28609484
ENSG00000099783
HNRNPM
breast cancer
29036465
ENSG00000099783
HNRNPM
breast cancer
30021377
ENSG00000099783
HNRNPM
Triple-Negative Breast Cancer
30093560
ENSG00000099783
HNRNPM
colorectal cancer
30852162
ENSG00000099783
HNRNPM
prostate cancer
31251827
ENSG00000099783
HNRNPM
breast cancer
31666932
ENSG00000099783
HNRNPM
breast cancer
31737791
ENSG00000099783
HNRNPM
Tumor
31803364
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000099783
HNRNPM
MESO
0.016
high
show
ENSG00000099783
HNRNPM
SARC
0.0075
high
show
ENSG00000099783
HNRNPM
STAD
9e-04
low
show
ENSG00000099783
HNRNPM
UVM
0.0036
low
show
ENSG00000099783
HNRNPM
PAAD
0.014
low
show
ENSG00000099783
HNRNPM
UCEC
0.02
low
show
ENSG00000099783
HNRNPM
THCA
0.023
high
show
ENSG00000099783
HNRNPM
HNSC
0.00019
low
show
ENSG00000099783
HNRNPM
READ
0.0032
low
show
ENSG00000099783
HNRNPM
KIRP
0.032
high
show
ENSG00000099783
HNRNPM
KICH
0.04
high
show
ENSG00000099783
HNRNPM
LUAD
0.02
high
show
ENSG00000099783
HNRNPM
THYM
0.00094
low
show
ENSG00000099783
HNRNPM
UCS
0.015
low
show
ENSG00000099783
HNRNPM
ESCA
6e-04
high
show
ENSG00000099783
HNRNPM
OV
0.012
low
show
ENSG00000099783
HNRNPM
DLBC
0.0047
low
show
ENSG00000099783
HNRNPM
KIRC
0.00023
low
show
ENSG00000099783
HNRNPM
PRAD
0.005
high
show
ENSG00000099783
HNRNPM
SKCM
0.025
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000099783
HNRNPM
LUSC
Del
1.069566
0.071096
0.337074
0.403194
ENSG00000099783
HNRNPM
LUAD
Del
0.760384
0.052034
0.337995
0.529070
ENSG00000099783
HNRNPM
CESC
Del
2.873041
0.103861
0.433016
0.291525
ENSG00000099783
HNRNPM
UCS
Del
4.293397
0.436927
0.598644
0.589286
ENSG00000099783
HNRNPM
ESCA
Del
1.472601
0.118856
0.330513
0.472826
ENSG00000099783
HNRNPM
HNSC
Del
2.288452
0.071140
0.321984
0.260536
ENSG00000099783
HNRNPM
LIHC
Del
4.642669
0.117628
0.457286
0.232432
ENSG00000099783
HNRNPM
BRCA
Del
0.680331
0.063054
0.348116
0.237963
ENSG00000099783
HNRNPM
STAD
Del
1.951969
0.077823
0.359715
0.344671
ENSG00000099783
HNRNPM
UCEC
Del
17.961561
0.159686
0.566170
0.194805
ENSG00000099783
HNRNPM
OV
Amp
1.122579
0.344373
0.746872
0.293610
ENSG00000099783
HNRNPM
OV
Del
16.493852
0.355835
0.576375
0.478411
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